CHEMBL28437


SMILES CCCN(CCC)C1CCc2cccc(OS(=O)(=O)C(F)(F)F)c2C1
InChIKey YEEMKPJFAQAHOW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 379.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Mouse 5-Hydroxytryptamine A pKi 9.1 9.1 9.1 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.9 7.41 7.92 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.17 6.17 6.17 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.02 8.02 8.02 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.56 6.56 6.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database