CHEMBL286527


SMILES C#CCn1c(=O)[nH]c2[nH]c(-c3ccc(Br)cc3)nc2c1=O
InChIKey MZKFWENNHZOFBS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 344.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
A2A AA2AR Rat Adenosine A pKi 6.7 6.7 6.7 ChEMBL
A1 AA1R Rat Adenosine A pKi 7.22 7.22 7.22 ChEMBL
A2B AA2BR Human Adenosine A pKi 8.17 8.17 8.17 ChEMBL
A3 AA3R Human Adenosine A pKi 6.32 6.32 6.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database