Ligand source activities (1 row/activity)
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Common name
| GPCRdb ID
| #Vendors | Reference ligand
| Fold selectivity | # Tested GPCRs | Species
| p-value (-log) | Activity Type
| Activity Relation
| Activity Value
| AssayType
| Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
|
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Assay information
| Chemical information
| ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Common name
| GPCRdb ID
| #Vendors | Reference ligand
| Fold selectivity | # Tested GPCRs | Species
| p-value (-log) | Activity Type
| Activity Relation
| Activity Value
| AssayType
| Assay Description
| Source
| Mol weight | Rot Bonds | H don | H acc | LogP | Smiles
| DOI
|
| 1499 | 2091 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | |
| 3779 | 2091 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | |
| 536 | 2091 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | |
| CHEMBL434 | 2091 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | |
| DB01064 | 2091 | 47 | None | -63 | 38 | Human | 8.3 | pEC50 | = | 8.3 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
ChEMBL | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | nan | |
| 1499 | 2091 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | |
| 3779 | 2091 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | |
| 536 | 2091 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | |
| CHEMBL434 | 2091 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | |
| DB01064 | 2091 | 47 | None | -63 | 38 | Human | 8.1 | pEC50 | = | 8.1 | Functional | Agonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assayAgonist activity at human TAS2R9 expressed in HEK293T cells co-expressing Galpha15 assessed as increase in intracellular calcium level by Calcium-3 dye based fluorescence assay |
Drug Central | 211 | 4 | 4 | 4 | 1.1 | CC(NCC(c1ccc(c(c1)O)O)O)C | None | |
| 2270 | 3171 | 69 | None | -446 | 3 | Human | 2.6 | pEC50 | = | 2.6 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 235 | 6 | 2 | 3 | 1.3 | CCN(CCNC(=O)c1ccc(cc1)N)CC | 19092995 | |
| 4811 | 3171 | 69 | None | -446 | 3 | Human | 2.6 | pEC50 | = | 2.6 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 235 | 6 | 2 | 3 | 1.3 | CCN(CCNC(=O)c1ccc(cc1)N)CC | 19092995 | |
| 4913 | 3171 | 69 | None | -446 | 3 | Human | 2.6 | pEC50 | = | 2.6 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 235 | 6 | 2 | 3 | 1.3 | CCN(CCNC(=O)c1ccc(cc1)N)CC | 19092995 | |
| CHEMBL640 | 3171 | 69 | None | -446 | 3 | Human | 2.6 | pEC50 | = | 2.6 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 235 | 6 | 2 | 3 | 1.3 | CCN(CCNC(=O)c1ccc(cc1)N)CC | 19092995 | |
| DB01035 | 3171 | 69 | None | -446 | 3 | Human | 2.6 | pEC50 | = | 2.6 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 235 | 6 | 2 | 3 | 1.3 | CCN(CCNC(=O)c1ccc(cc1)N)CC | 19092995 | |
| 2200 | 3131 | 46 | None | -239883 | 10 | Human | 2.7 | pEC50 | = | 2.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 351 | 2 | 1 | 5 | 1.6 | CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 | 19092995 | |
| 328 | 3131 | 46 | None | -239883 | 10 | Human | 2.7 | pEC50 | = | 2.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 351 | 2 | 1 | 5 | 1.6 | CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 | 19092995 | |
| 4848 | 3131 | 46 | None | -239883 | 10 | Human | 2.7 | pEC50 | = | 2.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 351 | 2 | 1 | 5 | 1.6 | CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 | 19092995 | |
| CHEMBL9967 | 3131 | 46 | None | -239883 | 10 | Human | 2.7 | pEC50 | = | 2.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 351 | 2 | 1 | 5 | 1.6 | CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 | 19092995 | |
| DB00670 | 3131 | 46 | None | -239883 | 10 | Human | 2.7 | pEC50 | = | 2.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 351 | 2 | 1 | 5 | 1.6 | CN1CCN(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1nccc2 | 19092995 | |
| 10918 | 2909 | 118 | None | -45708 | 3 | Human | 3.7 | pEC50 | = | 3.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 361 | 2 | 1 | 6 | 1.5 | CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C | 19092995 | |
| 1981 | 2909 | 118 | None | -45708 | 3 | Human | 3.7 | pEC50 | = | 3.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 361 | 2 | 1 | 6 | 1.5 | CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C | 19092995 | |
| 4583 | 2909 | 118 | None | -45708 | 3 | Human | 3.7 | pEC50 | = | 3.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 361 | 2 | 1 | 6 | 1.5 | CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C | 19092995 | |
| CHEMBL4 | 2909 | 118 | None | -45708 | 3 | Human | 3.7 | pEC50 | = | 3.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 361 | 2 | 1 | 6 | 1.5 | CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C | 19092995 | |
| DB01165 | 2909 | 118 | None | -45708 | 3 | Human | 3.7 | pEC50 | = | 3.7 | Functional | UnclassifiedUnclassified |
Guide to Pharmacology | 361 | 2 | 1 | 6 | 1.5 | CN1CCN(CC1)c1c(F)cc2c3c1OCC(n3cc(c2=O)C(=O)O)C | 19092995 | |
Showing 1 to 25 of 25 entries
| Ligands (move mouse cursor over ligand name to see structure) | Receptor | Assay information | Chemical information | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sel. page | Similar- ity
| Common name
| GPCRdb ID | #Vendors
| Reference ligand | Fold selectivity | # Tested GPCRs
| Species | p-value (-log)
| Activity Type
| Activity Relation
| Activity Value
| Assay Type
| Assay Description
| Source | Mol weight | Rot Bonds | H don | H acc | LogP
| Smiles
| DOI |
Ligands (move mouse cursor over ligand name to see structure)
| Receptor
| Assay information
| Chemical information
| |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sel. page | Similar- ity
| Common name
| GPCRdb ID | #Vendors
| Reference ligand | Fold selectivity | # Tested GPCRs
| Species | p-value (-log)
| Activity Type
| Activity Relation
| Activity Value
| Assay Type
| Assay Description
| Source | Mol weight | Rot Bonds | H don | H acc | LogP
| Smiles
| DOI |
| No data available in table | ||||||||||||||||||||||
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