OR1F1 (or1f1_human)

FAMILY

Class O2 (tetrapod specific odorant) Odorant receptors Odorant family 1 OR1F1

GENE

OR1F1 (OLFMF, OR1F10, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9)

ORGANISM

Human (Homo sapiens)

ALT. NAMES

Olfactory receptor 1F1, Olfactory receptor 16-35, OR16-35, Olfactory receptor 1F10, Olfactory receptor 1F4, Olfactory receptor 1F5, Olfactory receptor 1F6, Olfactory receptor 1F7, Olfactory receptor 1F8, Olfactory receptor 1F9, Olfactory receptor OR16-4

SOURCE

SWISSPROT

SEQUENCE

N-term        
M
S
G
T
N
Q
S
S
V
S
10
                   
E
F
L
L
L
G
L
S
R
Q
20
TM1              
P
Q
Q
Q
H
L
L
F
V
F
30
                   
F
L
S
M
Y
L
A
T
V
L
40
                   
G
N
L
L
I
I
L
S
V
S
50
    ICL1 TM2  
I
D
S
C
L
H
T
P
M
Y
60
                   
F
F
L
S
N
L
S
F
V
D
70
                   
I
C
F
S
F
T
T
V
P
K
80
                   
M
L
A
N
H
I
L
E
T
Q
90
ECL1 TM3      
T
I
S
F
C
G
C
L
T
Q
100
                   
M
Y
F
V
F
M
F
V
D
M
110
                   
D
N
F
L
L
A
V
M
A
Y
120
                   
D
H
F
V
A
V
C
H
P
L
130
ICL2     TM4  
H
Y
T
A
K
M
T
H
Q
L
140
                   
C
A
L
L
V
A
G
L
W
V
150
                   
V
A
N
L
N
V
L
L
H
T
160
        ECL2    
L
L
M
A
P
L
S
F
C
A
170
                   
D
N
A
I
T
H
F
F
C
D
180
                   
V
T
P
L
L
K
L
S
C
S
190
  TM5            
D
T
H
L
N
E
V
I
I
L
200
                   
S
E
G
A
L
V
M
I
T
P
210
                   
F
L
C
I
L
A
S
Y
M
H
220
                   
I
T
C
T
V
L
K
V
P
S
230
TM6              
T
K
G
R
W
K
A
F
S
T
240
                   
C
G
S
H
L
A
V
V
L
L
250
                   
F
Y
S
T
I
I
A
V
Y
F
260
ECL3     TM7  
N
P
L
S
S
H
S
A
E
K
270
                   
D
T
M
A
T
V
L
Y
T
V
280
                   
V
T
P
M
L
N
P
F
I
Y
290
      H8          
S
L
R
N
R
Y
L
K
G
A
300
                   
L
K
K
V
V
G
R
V
V
F
310
  C-term
S
V

LINKS

UniProt

DIAGRAMS

7TM

ICL1 S C L H ICL1ECL1 E T Q T I ECL1ICL2 P L H Y T A K M ICL2ECL2 P L S F C A D N A I T H F F C D V T P L L K L S C S D ECL2ICL3 V P ICL3ECL3 N P L S S H ECL3N-term M S G T N Q S S V S E F L L L G L S R N-termC-term V C-term Q P Q Q Q H L L F V F F L S M Y L A T V L G N L L I I L S V S I D T P M Y F F L S N L S F V D I C F S F T T V P K M L A N H I L S F C G C L T Q M Y F V F M F V D M D N F L L A V M A Y D H F V A V C H T H Q L C A L L V A G L W V V A N L N V L L H T L L M A T H L N E V I I L S E G A L V M I T P F L C I L A S Y M H I T C T V L K S T K G R W K A F S T C G S H L A V V L L F Y S T I I A V Y F S A E K D T M A T V L Y T V V T P M L N P F I Y S L R N R Y L K K V V F L K G A V V G R S
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

L N G L V T A L Y M S L F F V F L L H Q 1 S N L S F V D I C F S F T T V P K M L A 2 V A L L F N D M D V F M F V F Y M Q T L 3 C A L L V A G L W V V A N L N V L L H T 4 Y S A L I C L F P T I M V L A G E S L I 5 G S H L A V V L L F Y S T I I A V Y F 6 F P N L M P T V V T Y L V T A M T D K 7
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Invitro Mutant Data: Increased binding/potency: >5-fold, >10-fold; Reduced binding/potency: >5-fold, >10-fold; No/low effect (<5-fold); and N/A

MUTATIONS

0 mutation data points available.

PHYSIOLOGICAL LIGANDS

No physiological ligands available

STRUCTURE MODELS

or1f1_human inactive,

or1f1_human active

STRUCTURES

Found 1 structure(s) - view all details on the Structures page

PDBs: 8UXY