Ligand source activities (1 row/activity)



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Ligands (move mouse cursor over ligand name to see structure) Receptor Assay information Chemical information
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ligand		 Fold
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GPCRs		 Species

 p-value
(-log)		 Activity
Type		 Activity
Relation		 Activity
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 Assay
Description		 Source

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 DOI
90012275 133651 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
CHEMBL3714858 133651 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 416 6 2 3 5.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(C)(C)C)c1 nan
56593334 134121 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716462 134121 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011833 134301 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
CHEMBL3717071 134301 0 None - 1 Human 6.0 pAC50 = 6.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc([N+](=O)[O-])c1 nan
56593330 134386 0 None - 1 Human 6.9 pAC50 = 6.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134386 0 None - 1 Human 6.9 pAC50 = 6.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593346 134331 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
CHEMBL3717178 134331 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F nan
90010727 133814 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
CHEMBL3715451 133814 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 487 6 2 4 4.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cncc(I)c1 nan
118037864 133882 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
CHEMBL3715676 133882 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 3 3 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2nc[nH]c12 nan
2806493 134118 4 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
CHEMBL3716450 134118 4 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 nan
118037922 134686 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718384 134686 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 612 8 2 6 6.1 CC(C)(C)OC(=O)N1CCN(CCOc2ccccc2C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
90010869 134865 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
CHEMBL3718995 134865 0 None - 1 Human 5.9 pAC50 = 5.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 392 6 2 4 4.9 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC)c1 nan
38269206 134680 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718363 134680 0 None - 1 Human 4.9 pAC50 = 4.9 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90010751 134372 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3717338 134372 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C\c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
90012348 134586 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3718077 134586 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc([N+](=O)[O-])cc1 nan
90010773 133911 0 None -1 2 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
CHEMBL3715750 133911 0 None -1 2 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 375 4 2 4 4.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccno1 nan
90011033 134873 0 None - 1 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
CHEMBL3719015 134873 0 None - 1 Human 4.8 pAC50 = 4.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2ccccc2c1 nan
56593309 133762 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715203 133762 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90011788 133826 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3715489 133826 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
90012098 134580 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
CHEMBL3718061 134580 0 None - 1 Human 5.8 pAC50 = 5.8 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Br)c1 nan
56593314 134340 0 None - 1 Human 6.7 pAC50 = 6.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134340 0 None - 1 Human 6.7 pAC50 = 6.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593340 134100 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3716394 134100 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1313624 134448 8 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
CHEMBL3717590 134448 8 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(Cl)c1 nan
56593311 134487 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717723 134487 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
24671974 134792 2 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
CHEMBL3718728 134792 2 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 3 5.3 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccs1 nan
90012130 133685 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3714976 133685 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 409 4 2 3 5.1 N#Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
90010778 134213 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
CHEMBL3716808 134213 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 7 2 3 5.6 C/C=C/c1cccc(NC(=O)c2ccccc2NC(=O)c2ccccc2OCC)c1 nan
56593317 134948 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
CHEMBL3719257 134948 0 None - 1 Human 5.7 pAC50 = 5.7 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 nan
40622265 133880 2 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
CHEMBL3715664 133880 2 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 374 4 2 3 4.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccco1 nan
127024729 134476 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717683 134476 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 500 7 2 6 4.0 CCOc1ccccc1C(=O)NC1SC=CC1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010630 134797 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
CHEMBL3718740 134797 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 404 4 2 2 5.7 CC1CCC(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)CC1 nan
5298634 134958 10 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
CHEMBL3719295 134958 10 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 nan
56593335 134305 0 None - 1 Human 6.6 pAC50 = 6.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134305 0 None - 1 Human 6.6 pAC50 = 6.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011775 133672 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
CHEMBL3714926 133672 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Cl)cc1 nan
90011735 133770 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
CHEMBL3715244 133770 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 511 8 2 4 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCCCC1 nan
56593308 134159 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716596 134159 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593324 134216 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3716811 134216 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 478 8 2 5 5.2 CCOc1ccccc1C(=O)Nc1ccccc1CNc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593333 134235 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716871 134235 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593350 134647 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718273 134647 0 None - 1 Human 5.6 pAC50 = 5.6 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593315 134312 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134312 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010752 133695 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3714999 133695 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 448 4 2 2 5.1 O=C(Nc1cccc(I)c1)c1ccccc1NC(=O)C1CCCCC1 nan
90011874 133712 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
CHEMBL3715040 133712 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)c1 nan
56593323 133736 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715105 133736 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593318 134132 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
CHEMBL3716512 134132 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 nan
90010791 134272 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
CHEMBL3716987 134272 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccccn1 nan
56593313 134851 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
CHEMBL3718895 134851 0 None - 1 Human 4.5 pAC50 = 4.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 nan
56593329 134433 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717553 134433 0 None - 1 Human 6.5 pAC50 = 6.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593336 133843 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715551 133843 0 None - 1 Human 5.5 pAC50 = 5.5 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593337 133732 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
CHEMBL3715097 133732 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl nan
127024591 133743 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715139 133743 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 457 8 3 4 4.8 CNCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
2233108 134469 9 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3717655 134469 9 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1511185 133837 12 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3715535 133837 12 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
4795548 134237 5 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716878 134237 5 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
32157880 134243 4 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3716901 134243 4 None - 1 Human 4.4 pAC50 = 4.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1ccc(F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010785 133687 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3714984 133687 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 574 5 2 4 5.1 O=C(Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1I nan
118043134 133735 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
CHEMBL3715104 133735 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 4 2 2 7.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
21179517 133949 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715901 133949 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 4 2 2 6.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1cccc(C(F)(F)F)c1 nan
56593306 134294 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717045 134294 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90012794 134512 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
CHEMBL3717803 134512 0 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(Br)cc1 nan
54784887 134682 2 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
CHEMBL3718373 134682 2 None - 1 Human 5.4 pAC50 = 5.4 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 356 4 2 2 5.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1Nc1ccccc1 nan
1313916 40096 8 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40096 8 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593322 133725 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133725 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593331 134726 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718541 134726 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011206 133809 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
CHEMBL3715429 133809 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 513 8 2 5 4.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCCN1CCOCC1 nan
56593347 133839 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715539 133839 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010797 133865 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
CHEMBL3715615 133865 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 442 4 2 2 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C12CC3CC(CC(C3)C1)C2 nan
4484023 134269 6 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3716976 134269 6 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593338 134731 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3718557 134731 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 8 2 5 3.1 CCOc1ccccc1C(=O)NCCC(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593307 134821 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718811 134821 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 386 5 2 3 5.7 COc1ccccc1Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011315 134205 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
CHEMBL3716765 134205 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 370 5 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1ccccc1 nan
127024076 134489 1 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717734 134489 1 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 308 4 2 2 3.5 O=CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010896 134529 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
CHEMBL3717869 134529 0 None - 1 Human 4.3 pAC50 = 4.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 438 5 2 2 6.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCc1cccc(C(F)(F)F)c1 nan
56593316 133768 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133768 0 None - 1 Human 7.3 pAC50 = 7.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593341 133835 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715526 133835 0 None - 1 Human 6.3 pAC50 = 6.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 508 7 2 5 5.6 CCSc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
90010758 133817 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
CHEMBL3715462 133817 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 5 2 2 6.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccccc2)c1 nan
56593299 134013 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3716127 134013 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
56593339 134125 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716488 134125 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593319 134217 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716813 134217 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010729 134223 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
CHEMBL3716829 134223 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 429 6 2 4 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(N2CCCCC2)c1 nan
90010865 134722 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3718514 134722 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 380 3 2 3 5.3 CC(C)(C)OC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010599 134962 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3719301 134962 0 None - 1 Human 5.3 pAC50 = 5.3 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 364 5 2 2 5.6 CC(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
90011364 134059 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
CHEMBL3716260 134059 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 376 5 2 2 6.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCC1CCCCC1 nan
90011496 134149 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
CHEMBL3716563 134149 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 434 4 2 2 6.4 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1cccc2ccccc12 nan
90011579 134270 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
CHEMBL3716978 134270 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)cc1 nan
56593303 134617 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
CHEMBL3718178 134617 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 nan
60288826 134648 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718279 134648 1 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 426 5 2 3 5.4 CC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
56593326 134747 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718612 134747 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 nan
56593302 133776 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715266 133776 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011338 133792 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715346 133792 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 485 9 2 4 5.5 CN(C)CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593298 134482 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717700 134482 0 None - 1 Human 4.2 pAC50 = 4.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 400 6 2 3 5.6 COc1ccccc1CNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90010708 134295 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
CHEMBL3717047 134295 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 6 2 4 4.5 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C#N)c1 nan
118043136 134925 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3719197 134925 0 None - 1 Human 6.2 pAC50 = 6.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 460 7 2 4 6.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
90010848 133734 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
CHEMBL3715101 133734 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 424 6 2 5 3.6 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(C)(=O)=O)c1 nan
90010777 134577 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
CHEMBL3718054 134577 0 None - 1 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 346 4 2 2 4.4 C#Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 nan
118037818 134709 0 None -1 2 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
CHEMBL3718470 134709 0 None -1 2 Human 5.2 pAC50 = 5.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 428 4 2 4 4.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)OCO2 nan
56593305 134690 0 None - 1 Human 7.2 pAC50 = 7.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134690 0 None - 1 Human 7.2 pAC50 = 7.2 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
90010645 133791 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
CHEMBL3715345 133791 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 486 6 2 3 5.2 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(I)c1 nan
56593345 133907 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715743 133907 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593320 134142 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716540 134142 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011367 134774 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
CHEMBL3718664 134774 0 None - 1 Human 6.1 pAC50 = 6.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 476 6 2 3 7.0 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1Oc1ccccc1 nan
56593296 134157 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3716581 134157 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
90011087 134273 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
CHEMBL3716990 134273 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 452 4 2 2 6.2 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1C(F)(F)F nan
90011219 134658 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
CHEMBL3718291 134658 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 510 4 2 2 5.8 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1I nan
90011247 134716 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
CHEMBL3718498 134716 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 4 2 2 6.0 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Br nan
52764307 134868 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
CHEMBL3719005 134868 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccncc1 nan
90010748 133737 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715107 133737 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1ccc([N+](=O)[O-])cc1)c1ccccc1NC(=O)C1CCCCC1 nan
90010731 133894 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
CHEMBL3715708 133894 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 361 6 2 4 4.0 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1ccncc1 nan
3348337 134449 1 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717591 134449 1 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 3 2 2 3.9 CC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
29448220 134862 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3718975 134862 0 None - 1 Human 4.1 pAC50 = 4.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 366 4 2 4 4.2 O=C(Nc1ccc2c(c1)OCO2)c1ccccc1NC(=O)C1CCCCC1 nan
56593344 133697 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3715001 133697 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593325 134767 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
CHEMBL3718643 134767 0 None - 1 Human 5.1 pAC50 = 5.1 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 nan
56593349 2571 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2571 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2571 30 None - 1 Human 7.0 pAC50 = 7.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
90011702 133752 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3715166 133752 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 362 4 2 2 4.9 O=C(Nc1ccc2c(c1)CCC2)c1ccccc1NC(=O)C1CCCCC1 nan
56593321 134486 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717718 134486 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 nan
90011489 134599 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
CHEMBL3718114 134599 0 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 384 6 2 2 5.6 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NCCc1ccccc1 nan
60589025 134795 1 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
CHEMBL3718735 134795 1 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 462 5 2 4 4.6 CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 nan
1320335 134822 9 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
CHEMBL3718813 134822 9 None - 1 Human 5.0 pAC50 = 5.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 nan
730108 41539 17 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1491180 41539 17 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 nan
56593342 134417 0 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL3717485 134417 0 None - 1 Human 4.0 pAC50 = 4.0 Functional
Agonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assayAgonist activity at RXFP1 receptor (unknown origin) expressed in HEK293 cells assessed as stimulation of cAMP production incubated for 30 mins by TR-FRET based HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 nan
162654489 180635 0 None 4 2 Human 10.5 pEC50 = 10.5 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180635 0 None 4 2 Human 10.5 pEC50 = 10.5 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162648163 179873 0 None - 1 Human 10.0 pEC50 = 10 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179873 0 None - 1 Human 10.0 pEC50 = 10 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183199 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183199 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162667576 182484 0 None - 1 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182484 0 None - 1 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654489 180635 0 None 4 2 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180635 0 None 4 2 Human 9.4 pEC50 = 9.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162677247 183530 0 None - 1 Human 9.2 pEC50 = 9.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183530 0 None - 1 Human 9.2 pEC50 = 9.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162661030 181449 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181449 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183352 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183352 0 None - 1 Human 9.0 pEC50 = 9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133768 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715235 133768 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593334 134121 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716462 134121 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 454 5 2 4 4.8 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593305 134690 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
CHEMBL3718400 134690 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F nan
56593346 134331 0 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3717178 134331 0 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 468 5 2 3 6.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OC(F)(F)F 10.1016/j.ejmech.2018.06.008
162664297 182081 0 None -2 2 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781560 182081 0 None -2 2 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593322 133725 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3715081 133725 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162649438 180052 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4747756 180052 0 None - 1 Human 6.9 pEC50 = 6.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3412 125 54 48 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
2806493 134118 4 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
CHEMBL3716450 134118 4 None - 1 Human 5.9 pEC50 = 5.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 384 4 2 2 5.2 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1 10.1016/j.ejmech.2018.06.008
38269206 134680 0 None - 1 Human 4.9 pEC50 = 4.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718363 134680 0 None - 1 Human 4.9 pEC50 = 4.9 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 340 4 2 2 4.6 O=C(Nc1cccc(F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162659815 181200 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761130 181200 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2785 100 45 39 -13.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162666079 182313 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4784237 182313 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2855 106 46 40 -12.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162656358 180889 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757578 180889 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3355 121 53 47 -14.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677445 183543 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4800116 183543 0 None - 1 Human 6.8 pEC50 = 6.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3139 113 49 43 -12.2 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593309 133762 0 None - 1 Human 5.8 pEC50 = 5.8 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715203 133762 0 None - 1 Human 5.8 pEC50 = 5.8 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ncccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162646950 179679 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4743539 179679 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3195 119 50 44 -12.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162643258 181742 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
CHEMBL4777259 181742 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3411 126 53 47 -12.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NCC(C)C(=O)NCC(C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O 10.1021/acs.jmedchem.0c01533
162674863 183313 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797258 183313 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3509 135 52 47 -9.4 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162662427 181958 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4779982 181958 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3383 123 53 47 -14.2 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162648609 179815 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744987 179815 0 None - 1 Human 7.8 pEC50 = 7.8 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3292 122 50 45 -12.0 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672427 183199 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4795810 183199 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4880 202 66 67 -10.3 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593314 134340 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717211 134340 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593330 134386 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717389 134386 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1313916 40096 8 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1479446 40096 8 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593340 134100 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716394 134100 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1cccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)c1 10.1016/j.ejmech.2018.06.008
56593311 134487 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717723 134487 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 422 5 2 3 6.1 O=C(Nc1cccc(SC(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
162650672 180156 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748931 180156 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3152 116 49 43 -12.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162648163 179873 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4745611 179873 0 None - 1 Human 7.7 pEC50 = 7.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4895 203 66 67 -9.3 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2571 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
8322 2571 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
CHEMBL3716980 2571 30 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C nan
162659417 181226 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4761424 181226 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3257 114 52 46 -15.6 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670766 182952 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4792874 182952 0 None - 1 Human 6.7 pEC50 = 6.7 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3097 111 49 43 -13.1 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593317 134948 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719257 134948 0 None - 1 Human 5.7 pEC50 = 5.7 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 404 4 2 2 5.9 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCCC1 10.1016/j.ejmech.2018.06.008
162654519 180670 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4755239 180670 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2828 103 46 40 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654037 180674 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4755289 180674 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3424 126 53 47 -12.7 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
5298634 134958 10 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3719295 134958 10 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 376 4 2 2 5.1 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCC1 10.1016/j.ejmech.2018.06.008
56593332 162251 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4163593 162251 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 498 7 2 6 4.9 CCOc1ccccc1C(=O)Nc1sccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162667576 182484 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4786789 182484 0 None - 1 Human 7.6 pEC50 = 7.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 5414 233 69 76 -9.5 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)COCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593335 134305 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717089 134305 0 None - 1 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593308 134159 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716596 134159 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 466 5 2 2 7.1 O=C(Nc1cccc(-c2ccccc2C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593333 134235 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716871 134235 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 400 4 2 2 5.2 O=C(Nc1cccc(Br)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593350 134647 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718273 134647 0 None - 1 Human 5.6 pEC50 = 5.6 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 4 2 2 5.8 CC(C)(C)c1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162672610 183016 0 None -35 2 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 183016 0 None -35 2 Human 6.6 pEC50 = 6.6 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593323 133736 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715105 133736 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cnccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593318 134132 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3716512 134132 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 362 4 2 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCC1 10.1016/j.ejmech.2018.06.008
56593313 134851 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718895 134851 0 None - 1 Human 4.5 pEC50 = 4.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 428 5 1 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)N(C)c1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162652974 180417 0 None - 1 Human 8.5 pEC50 = 8.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4752287 180417 0 None - 1 Human 8.5 pEC50 = 8.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4163 175 54 60 -9.4 CCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162672610 183016 0 None -35 2 Human 8.4 pEC50 = 8.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 183016 0 None -35 2 Human 8.4 pEC50 = 8.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162674882 183352 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4797641 183352 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4191 177 54 60 -8.7 CCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162669540 182639 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4788675 182639 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2867 105 45 40 -11.9 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162670803 182836 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4791290 182836 0 None - 1 Human 7.5 pEC50 = 7.5 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3314 119 53 47 -14.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593329 134433 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717553 134433 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593336 133843 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3715551 133843 0 None - 1 Human 5.5 pEC50 = 5.5 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 356 4 2 2 5.1 O=C(Nc1cccc(Cl)c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593314 134340 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717211 134340 0 None - 1 Human 6.5 pEC50 = 6.5 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 478 6 2 5 4.5 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
56593330 134386 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
CHEMBL3717389 134386 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 492 7 2 5 4.9 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 nan
162648114 179915 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4746080 179915 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4489 180 64 59 -8.3 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162649375 180120 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4748601 180120 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3327 120 53 47 -15.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593337 133732 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
CHEMBL3715097 133732 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 418 4 2 2 5.9 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1ccccc1Cl 10.1016/j.ejmech.2018.06.008
56593300 162201 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL4162685 162201 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 471 8 2 4 5.2 CN(C)CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
1511185 133837 12 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715535 133837 12 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 336 4 2 2 4.8 Cc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
4795548 134237 5 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716878 134237 5 None - 1 Human 4.4 pEC50 = 4.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 352 5 2 3 4.5 COc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
162646638 179714 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4743958 179714 0 None - 1 Human 6.4 pEC50 = 6.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3055 109 49 43 -14.1 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593306 134294 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3717045 134294 0 None - 1 Human 5.4 pEC50 = 5.4 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 4 2 2 5.5 Cc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162644941 179400 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4739969 179400 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2883 107 46 40 -11.8 CC[C@H](C)[C@H](NC(=O)C(C)CNC(=O)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162649856 180139 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4748830 180139 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3481 130 54 48 -12.8 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
162663002 182048 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781139 182048 0 None - 1 Human 7.4 pEC50 = 7.4 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3122 115 48 43 -11.7 CCCC[C@H](OC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162655145 180758 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4756139 180758 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3166 116 49 43 -11.4 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593322 133725 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715081 133725 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 520 9 2 5 5.7 CCCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
47936 193422 88 None 25 6 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
CHEMBL52606 193422 88 None 25 6 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 410 2 3 7 1.5 C=C[C@@]1(C)CC(=O)[C@@]2(O)[C@](C)(O1)[C@@H](OC(C)=O)[C@@H](O)[C@H]1C(C)(C)CC[C@H](O)[C@@]12C 10.1016/j.ejmech.2018.06.008
56593331 134726 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3718541 134726 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 442 6 2 3 6.0 CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593335 134305 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL3717089 134305 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 428 6 2 3 5.6 CCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
56593347 133839 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715539 133839 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1cccnc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654330 179754 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4744303 179754 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3299 116 52 46 -14.6 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593316 133768 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715235 133768 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 8 2 5 5.3 CCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162654892 180620 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4754697 180620 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3083 110 49 43 -13.3 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593315 134312 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
CHEMBL3717103 134312 0 None - 1 Human 6.3 pEC50 = 6.3 Functional
Agonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assayAgonist activity at RXFP1 receptor in human THP1 cells assessed as stimulation of cAMP production incubated for 30 mins by HTRF assay
ChEMBL 446 6 2 4 5.8 COc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(SC(F)(F)F)c1 nan
56593299 134013 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716127 134013 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 368 5 2 3 5.2 CSc1cccc(NC(=O)c2ccccc2NC(=O)C2CCCCC2)c1 10.1016/j.ejmech.2018.06.008
56593339 134125 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716488 134125 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 378 6 2 2 5.3 CCC(CC)C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593319 134217 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716813 134217 0 None - 1 Human 5.3 pEC50 = 5.3 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 364 6 2 2 5.1 CCCCC(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162670817 182849 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
CHEMBL4791486 182849 0 None - 1 Human 7.3 pEC50 = 7.3 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3209 121 50 44 -11.0 CC[C@H](C)[C@H](NC[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O 10.1021/acs.jmedchem.0c01533
56593303 134617 1 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718178 134617 1 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 385 4 2 3 4.6 O=C(Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1 10.1016/j.ejmech.2018.06.008
56593326 134747 0 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718612 134747 0 None - 1 Human 5.2 pEC50 = 5.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 367 5 2 4 4.4 O=C(Nc1cccc([N+](=O)[O-])c1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593302 133776 0 None - 1 Human 4.2 pEC50 = 4.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715266 133776 0 None - 1 Human 4.2 pEC50 = 4.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 338 6 2 3 4.0 COCCNc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593305 134690 0 None - 1 Human 7.2 pEC50 = 7.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
CHEMBL3718400 134690 0 None - 1 Human 7.2 pEC50 = 7.2 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 546 7 2 5 5.4 O=C(Nc1cccc(S(=O)(=O)C(F)(F)F)c1)c1ccccc1NC(=O)c1ccccc1OCC(F)(F)F 10.1016/j.ejmech.2018.06.008
162656612 180917 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4757890 180917 0 None - 1 Human 6.2 pEC50 = 6.2 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3041 106 48 42 -13.3 CC[C@H](C)[C@H](NC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593345 133907 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715743 133907 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 493 7 2 6 4.3 CCOc1ccccc1C(=O)Nc1ccncc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593320 134142 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716540 134142 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 458 8 2 4 5.2 COCCOc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593296 134157 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3716581 134157 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 444 6 2 4 5.2 COc1cccc(OC)c1C(=O)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
162662592 181969 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4780098 181969 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in human HEK-293T cells co-transfected with pCRE beta-galactosidase reporter plasmid assessed as inhibition of IBMX-induced cAMP accumulation incubated for 30 mins by HTRF assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162675717 183277 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4796713 183277 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4461 178 64 59 -9.0 CCCC[C@H](NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCCNC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(N)=O)C(=O)CCCCCCCCCCCCCCCC(=O)O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593344 133697 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
CHEMBL3715001 133697 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 398 5 2 2 5.1 O=C(Cc1ccccc1)Nc1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 10.1016/j.ejmech.2018.06.008
56593325 134767 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
CHEMBL3718643 134767 0 None - 1 Human 5.1 pEC50 = 5.1 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 348 4 2 2 4.3 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CC1 10.1016/j.ejmech.2018.06.008
162661030 181449 0 None - 1 Human 7.1 pEC50 = 7.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4764326 181449 0 None - 1 Human 7.1 pEC50 = 7.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 4866 201 66 67 -10.6 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)COCCOCCNC(=O)COCCOCCNC(=O)COCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCC)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162661521 181530 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4765167 181530 0 None - 1 Human 6.1 pEC50 = 6.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3341 120 53 47 -14.6 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162677247 183530 0 None - 1 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
CHEMBL4799907 183530 0 None - 1 Human 8.1 pEC50 = 8.1 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins in presence of 2 % HSA by HTRF assay
ChEMBL 3441 156 40 48 -1.9 CCCCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCCCCNC(C)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC 10.1021/acs.jmedchem.0c01533
162666829 182425 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4785899 182425 0 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3069 110 49 43 -13.8 CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)C(=O)NC[C@H](C)C(=O)NC[C@H](C)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162664515 182075 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781482 182075 0 None - 1 Human 6.0 pEC50 = 6.0 Functional
Agonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at RXFP1 endogenously expressed in human OVCAR-5 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 3027 105 48 42 -13.5 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(C)=O)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
56593349 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
8322 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
CHEMBL3716980 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 10.1016/j.ejmech.2018.06.008
56593321 134486 0 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717718 134486 0 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 445 7 3 4 5.0 O=C(NCc1ccco1)c1ccccc1NC(=O)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
1320335 134822 9 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
CHEMBL3718813 134822 9 None - 1 Human 5.0 pEC50 = 5.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 414 5 2 3 5.2 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)cc1 10.1016/j.ejmech.2018.06.008
730108 41539 17 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL1491180 41539 17 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 322 4 2 2 4.5 O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
56593342 134417 0 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
CHEMBL3717485 134417 0 None - 1 Human 4.0 pEC50 = 4.0 Functional
Agonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assayAgonist activity at human RXFP1 expressed in HEK293 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay
ChEMBL 390 4 2 2 5.5 O=C(Nc1ccc(C(F)(F)F)cc1)c1ccccc1NC(=O)C1CCCCC1 10.1016/j.ejmech.2018.06.008
820020 21826 7 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
CHEMBL1319564 21826 7 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 2 2 3 1.6 O=C(NN=C1CCCC1)c1[nH]nc2c1CCC2 nan
2146184 44566 10 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
CHEMBL1519935 44566 10 None - 1 Human 7.0 pPotency = 7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 4 2.4 CN(C)c1ccc(C(=S)N2CCN(S(=O)(=O)c3ccccc3)CC2)cc1 nan
1761 99676 10 None - 1 Human 6.0 pPotency = 6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
CHEMBL28449 99676 10 None - 1 Human 6.0 pPotency = 6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 4 9 -1.7 Nc1ncnc2c1ncn2C1OC(C(=O)NC2CC2)C(O)C1O nan
16019574 10881 11 None -14 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
CHEMBL1172596 10881 11 None -14 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(F)cc1)c1sccc12 nan
4132952 19671 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
CHEMBL1300691 19671 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 11 0.2 CCOP1(=O)OCC2OC(n3cnc4c(N)ncnc43)C(O)C2O1 nan
54677759 21090 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
CHEMBL1312172 21090 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 3 4.1 O=c1c(Cc2ccccc2)c(O)c2cccc3c4c(n1c23)CCCC4 nan
16027480 21523 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
CHEMBL1316197 21523 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
941768 22091 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
CHEMBL1321879 22091 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 3 7 -0.5 O=C1NC(=O)C(=NNc2ccc3c(c2)COC3=O)C(=O)N1 nan
2764158 22647 30 None -2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
CHEMBL1326901 22647 30 None -2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 2 1 5 2.7 CSc1ccccc1-c1nnc(S)o1 nan
2810145 25936 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
CHEMBL1354031 25936 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 3.6 COc1cc2nc(NC(=O)c3ccc(Cl)cc3)sc(=O)c2cc1OC nan
16010496 26110 2 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
CHEMBL1356009 26110 2 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 6 0.6 Cc1ccc2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c(=O)n2c1 nan
2140949 26111 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
CHEMBL1356037 26111 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 7 4.8 COc1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1OC nan
2137373 27256 15 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
CHEMBL1366864 27256 15 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 7 4.5 Cc1cccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccccc23)c1C nan
16027547 27544 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
CHEMBL1369113 27544 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 8 4.5 CC(C)CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CCCCC4)sc3n2)cc1 nan
16009802 27878 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1371530 27878 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 5 4.9 CCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
17581362 28834 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
CHEMBL1379032 28834 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1cccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)c1 nan
4875840 29637 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
CHEMBL1386021 29637 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 2 4 2.5 COc1ccc(CNC(=O)CN2C(=O)NC(C)(c3cccc(Br)c3)C2=O)cc1 nan
1486264 30005 14 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
CHEMBL1388862 30005 14 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 Cc1ccc(Sc2ccc(NC(=O)c3ccc(S(C)(=O)=O)cc3Cl)cc2)cc1 nan
2810230 30435 6 None 2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
CHEMBL1392489 30435 6 None 2 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 1 4 3.9 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)C1CCC1 nan
16012884 30916 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
CHEMBL1397962 30916 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 7 3.1 COc1ccc(-n2ncc3c2ncn2nc(Cc4ccccc4)nc32)cc1 nan
16021838 30946 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
CHEMBL1398407 30946 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cccc(Cl)c2C)c(-c2ccccc2)n1 nan
2135605 31123 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
CHEMBL1400053 31123 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 4.6 c1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
15990902 31846 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
CHEMBL1406771 31846 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 2 3 5.7 Cc1cc(C)cc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
963186 32274 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
CHEMBL1410023 32274 8 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 3 4.2 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 nan
15989908 32276 9 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32276 9 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
15988850 32377 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
CHEMBL1410908 32377 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 3.6 O=C(Nc1ccc(F)cc1F)c1cc(-c2ccc3c(c2)OCO3)on1 nan
1128972 32485 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1411854 32485 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 0 5 4.3 CCOC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)c1C#N nan
3361436 34255 2 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
CHEMBL1426572 34255 2 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 4 4 4.2 Cc1ccc(NC(=S)NC(=O)c2ccccc2)cc1NC(=S)NC(=O)c1ccccc1 nan
1627636 34934 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1432353 34934 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 6 1.6 NN=C(S)Nc1cccc(-c2nnc(S)o2)c1 nan
8087251 35086 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1433615 35086 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccc(F)cc2)CC1 nan
16023146 35245 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
CHEMBL1435835 35245 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 7 4.9 CCOc1ccc(CNC(=O)CSc2nnc(C)c3c(C)n(-c4ccc(Cl)cc4)nc23)cc1 nan
1741544 37661 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
CHEMBL1457270 37661 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccccc1C(=O)Nc1ccc2oc(-c3cccc4c(Br)cccc34)nc2c1 nan
2136370 38147 4 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
CHEMBL1461369 38147 4 None -1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 3.3 CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccccc12 nan
3594053 39570 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
CHEMBL1473447 39570 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Cl)c1 nan
16241285 40485 2 None 1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
CHEMBL1482781 40485 2 None 1 2 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 2.3 CN(C)C=O.CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
1241177 41274 12 None -1 3 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
CHEMBL1489236 41274 12 None -1 3 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 0 8 2.4 c1ccc(COn2nnc3ccccc32)c(COn2nnc3ccccc32)c1 nan
16009541 41998 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
CHEMBL1495115 41998 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccc(F)cc4)cc3)cc(=O)n12 nan
2978485 42718 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1501669 42718 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 2 4.1 CCC(C)NC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
7514097 42765 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1502018 42765 10 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 4 6 2.2 O=C(O)CCNc1ccc(NCCC(=O)O)c2c1C(=O)c1ccccc1C2=O nan
5777938 42860 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1502864 42860 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 10 1 8 4.1 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
1256983 43592 14 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
CHEMBL1509228 43592 14 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 3 5.3 O=C(Nc1ccc(F)cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
16017574 43925 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1512435 43925 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 8 1 6 2.5 CCCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
15988274 44026 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1513838 44026 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
4921215 44181 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
CHEMBL1516149 44181 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 2 4 6.7 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)Nc3ccc(C)c(C)c3)sc2n1 nan
135466071 46256 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
CHEMBL1535161 46256 1 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 6 4.5 CCc1cc2c(s1)N1Cc3ccccc3C(C(=O)c3cccc([N+](=O)[O-])c3)=C1NC2=O nan
16024942 48259 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1553067 48259 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.7 CCc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16015892 48273 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
CHEMBL1553238 48273 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(-c2nc3cc(NC(=O)COc4ccc(C)c(C)c4)ccc3o2)cc1 nan
16028168 48942 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
CHEMBL1560108 48942 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 nan
16009056 49396 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
CHEMBL1564251 49396 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 3.7 COC(=O)c1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(C(=O)OC)c1 nan
626021 50344 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1572204 50344 12 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 4 3.0 CNC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
2462898 50766 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
CHEMBL1576381 50766 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 0 5 3.4 COc1ccc(C(C)=O)cc1COc1ncnc2ccccc12 nan
16024893 52413 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
CHEMBL1590399 52413 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 4.2 COc1ccc(OC)c(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
16010832 52444 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
CHEMBL1590845 52444 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.0 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3cccnc32)cc1C nan
16019294 52528 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
CHEMBL1591857 52528 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 1 8 5.2 Cc1cc(C)cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)c1 nan
3854561 52605 16 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
CHEMBL1592912 52605 16 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 5.5 N#Cc1c(C(F)(F)F)cc(-c2ccc(F)cc2)nc1SCC(=O)Nc1ccccc1 nan
16018208 53508 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1601478 53508 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
16025642 53660 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
CHEMBL1603009 53660 6 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 6 1 6 5.9 Cc1cccc(C)c1NC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
4402705 54735 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
CHEMBL1611899 54735 11 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 8 -0.5 CN1C(=O)C(=NNc2cccc(S(=O)(=O)N3CCOCC3)c2)C(=O)N(C)C1=O nan
16018210 54749 3 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1612043 54749 3 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 1 4 5.8 Cc1ccccc1NC(=O)c1oc2c(c1C)-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
2795741 79880 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
CHEMBL212314 79880 5 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 5 5.4 Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(Br)cc3Cl)s2)cs1 nan
3127110 107747 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
CHEMBL3191381 107747 13 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 1 8 2.9 C/C(=N\CCCn1ccnc1)c1c(C)nn(-c2ccc([N+](=O)[O-])cc2)c1O nan
1528721 108354 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
CHEMBL3198106 108354 7 None - 1 Human 5.0 pPotency = 5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 3.4 CC(=O)/N=c1\scc(-c2ccccc2)n1-c1cccc(O)c1 nan
414 3382 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
93205 3382 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
CHEMBL139000 3382 33 None -1445 5 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 4 9 0.5 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N[C@@H](Cc1ccccc1)C nan
24818570 21203 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
CHEMBL1312949 21203 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 3 4 3.8 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)cc1 nan
3138147 21672 14 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
CHEMBL1318270 21672 14 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 0 5 5.7 O=C(CSc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1)c1ccccc1 nan
5428505 23065 27 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
CHEMBL1330383 23065 27 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 0 1 3 3.3 O=c1oc2cc(O)c(Cl)cc2c2ccccc12 nan
5913370 24009 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1337918 24009 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 6 1 5 2.8 COCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
3694202 24357 19 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
CHEMBL1341012 24357 19 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Cl)c2)no1 nan
7190321 24732 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
CHEMBL1344120 24732 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 7 2.6 O=C(CSc1ccc2nnc(-c3cccs3)n2n1)N1CCCC1 nan
661441 24778 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24778 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24778 7 None -2 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
16017580 25313 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
CHEMBL1349094 25313 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 7 2.9 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Cl)s1 nan
3239502 26969 10 None 1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
CHEMBL1364442 26969 10 None 1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 9 0.3 COc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
7189863 29332 11 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
CHEMBL1383330 29332 11 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.9 O=C(Nc1nc2cc3c(cc2s1)OCO3)c1ccc(N2C(=O)CCC2=O)cc1 nan
16189478 29366 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1383621 29366 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 0 6 2.2 CCCCN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
2457625 30329 1 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
CHEMBL1391543 30329 1 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 7 -0.0 CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 nan
686152 30505 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30505 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30505 41 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
16009717 30805 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
CHEMBL1396454 30805 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 Fc1ccc(CNc2nc3c(-c4ccc(F)cc4)nnn3c3ccccc23)cc1 nan
24892133 30986 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1398694 30986 8 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 11 1.7 COc1ccccc1-c1nc(SCC(=O)Nc2cc(C)on2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
1115170 33178 15 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
CHEMBL1417596 33178 15 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 5 4.8 Cc1cccc(OCC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)c1 nan
15988646 35377 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
CHEMBL1437533 35377 2 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 4.9 COc1ccccc1NC(=O)c1sc(-c2ccc(Cl)cc2)cc1N nan
1341231 35493 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
CHEMBL1438558 35493 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 5 5.5 COc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
2999623 36590 7 None -1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
CHEMBL1448461 36590 7 None -1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 9 0 8 2.9 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(CCC(=O)OCc1c(C)noc1C)n2C nan
2609971 38759 6 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
CHEMBL1466287 38759 6 None -1 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 7 3.2 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O nan
16024828 41667 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
CHEMBL1492051 41667 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5F)CC4)ccc3c2)CC1 nan
3276076 42364 9 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1498535 42364 9 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 7 3.1 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
3494087 43808 4 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
CHEMBL1511159 43808 4 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 7 2.0 Cc1sc2ncnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)c2c1C nan
22513173 44131 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
CHEMBL1515462 44131 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 7 2.0 COc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccccc4F)ncn3n2)cc1 nan
16025349 44671 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
CHEMBL1520822 44671 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.6 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccccc1)S2(=O)=O)Nc1ccccc1 nan
16017252 45925 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
CHEMBL1532051 45925 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.1 Cc1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
659886 46231 13 None 1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
CHEMBL1534846 46231 13 None 1 3 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 5 5.4 CCc1ccccc1NC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCCC2 nan
790785 46271 11 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
CHEMBL1535349 46271 11 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 3 2 3 3.5 CCCc1c(C)nc2ccc(C(=O)O)cc2c1S nan
3767937 46712 13 None -3 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
CHEMBL1539280 46712 13 None -3 2 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 6 5.6 N#Cc1c(N)nc(SCC(=O)C23CC4CC(CC(C4)C2)C3)c(C#N)c1-c1ccc(Cl)cc1 nan
24792845 50386 3 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
CHEMBL1572639 50386 3 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 1.3 Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3ccccc3n12 nan
319257 50404 5 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
CHEMBL1572793 50404 5 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 4 2 2 3.0 C=C(C)C(=O)Nc1ccc(NC(C)C)cc1 nan
2100389 51698 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
CHEMBL1584231 51698 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 2.5 O=C(COc1ncnc2scc(-c3ccccc3)c12)NCCN1C(=O)CSC1=O nan
16019541 52442 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
CHEMBL1590799 52442 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 8 5.1 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(Nc2ccc(C)c(C)c2)c2sccc23)c1 nan
16025640 52500 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1591452 52500 6 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 5.6 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
1189472 52955 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
CHEMBL1596394 52955 13 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 2.9 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCN1CCOCC1 nan
1115820 54699 23 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1611566 54699 23 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 6 5.4 COc1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
9581898 72587 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
CHEMBL1992883 72587 10 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 5 2.0 Cc1cccc(C(=O)N/N=C2\CS(=O)(=O)N(C)c3ccsc32)c1 nan
17584449 109112 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL3213657 109112 7 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 0 7 2.6 COc1cc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2c2ccccc2)cc(OC)c1OC nan
CHEMBL1411485 208764 0 None - 1 Human 5.0 pPotency = 5.0 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL None None None None nan
377 2758 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
425 2758 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
448222 2758 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
CHEMBL464859 2758 53 None -371 10 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 4 9 -1.8 CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N nan
135415429 41306 7 None 2 3 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
CHEMBL1489478 41306 7 None 2 3 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 8 1 9 4.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)nc(SCc1nc(O)c3sccc3n1)n2CC nan
6076 107266 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL1363683 107266 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
CHEMBL316966 107266 67 None 1 2 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 3 10 -0.8 Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1O nan
20923189 19794 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
CHEMBL1301594 19794 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 0 6 2.1 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1 nan
613860 20213 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
CHEMBL1305078 20213 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 6 2.9 Cc1noc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)c1C nan
2480606 20423 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
CHEMBL1306773 20423 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 2 7 0.6 Cc1cccc(NCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
224672 22708 48 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
CHEMBL1327484 22708 48 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 3 1 3 3.1 O=C(O)CSc1ccnc2cc(Cl)ccc12 nan
2384232 22776 31 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
CHEMBL1327902 22776 31 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 4.2 Cc1sc2ncnc(Sc3ccccc3C(=O)O)c2c1C nan
1442817 23252 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
CHEMBL1331799 23252 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.6 Cc1nnc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)s1 nan
6103449 23873 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
CHEMBL1336606 23873 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 0 3 4.0 CCN1/C(=C2\C(=O)N(C)C(=S)N2c2ccccc2)C=Cc2ccccc21 nan
662886 23906 9 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
CHEMBL1336927 23906 9 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 7 3.5 Brc1ccc(-c2nn3c(-c4ccco4)nnc3s2)o1 nan
16011044 26695 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
CHEMBL1362040 26695 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)NC(=O)c2ccccc2S3)cc1 nan
826482 26817 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1363060 26817 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 250 1 2 6 1.8 CC1(C)Cc2c(sc3ncnc(NN)c23)CO1 nan
16024887 27225 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1366554 27225 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 4.6 CCOc1ccccc1CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
3207679 29153 4 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
CHEMBL1381650 29153 4 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1cccc2cc(C#N)c(SCC(=O)NCc3cccs3)nc12 nan
2445448 29644 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1386075 29644 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 0 7 1.4 COc1ccc(C(C)=O)cc1Cn1cnc2c(cnn2C)c1=O nan
15988012 30003 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1388847 30003 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
2917979 30083 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
CHEMBL1389475 30083 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 9 4.0 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)nc1C nan
686152 30505 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1393131 30505 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
CHEMBL1576064 30505 41 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 4.0 O=C(O)c1cc(-c2ccco2)nc2ccc(Br)cc12 nan
15987889 33214 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1417926 33214 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 8 1 4 5.4 CCN(CC)CC(C)CNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
20904552 33812 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1422972 33812 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 8 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
2375468 34933 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
CHEMBL1432350 34933 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 -0.2 Cn1c(N)c(C(=O)COc2ccc(C#N)cc2)c(=O)n(C)c1=O nan
16024881 35078 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1433473 35078 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 4 2.6 CNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
15991045 35087 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1433636 35087 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 3 1 3 7.0 Cc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
16015278 35174 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
CHEMBL1434956 35174 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 6 5.3 CC(=O)c1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4)c3C)nc2C)cc1 nan
5078950 35533 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1438931 35533 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
5310383 35968 11 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
CHEMBL1442757 35968 11 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 0.3 O=C(Cn1cnc2c(nnn2-c2ccccc2)c1=O)NCC1CCCO1 nan
948433 35981 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
CHEMBL1442938 35981 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 1 4 3.7 COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 nan
16019658 36242 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
CHEMBL1445403 36242 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 7 3.2 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1C nan
3208298 38826 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
CHEMBL1466770 38826 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 3.7 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1nccs1)OCO3 nan
6623284 39479 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
CHEMBL1472373 39479 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 0 7 3.0 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCCC2)s1 nan
5302642 39608 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1474011 39608 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 2 4 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2)cc1 nan
1203028 39633 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1474423 39633 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 2 8 0.0 CC(=O)Nc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
15988309 39966 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
CHEMBL1478365 39966 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 8 2.1 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
1387364 40803 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40803 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40803 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
4238273 40857 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
CHEMBL1485997 40857 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 6 2.9 Cn1c(SCC(=O)c2ccc3c(c2)NC(=O)CO3)nc2ccccc21 nan
16025632 41756 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
CHEMBL1492743 41756 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
1252362 42527 15 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
CHEMBL1499911 42527 15 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 5 5.2 COc1ccc(-n2c(-c3cccc(OC)c3)nc(=S)c3c2CCCC3)cc1 nan
3173852 42619 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
CHEMBL1500673 42619 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 4 3.8 CNC(=S)N(Cc1ccc(OC)cc1)Cc1cc2cc(C)ccc2nc1O nan
16189472 43255 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
CHEMBL1506287 43255 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 2.1 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)Nc1cccnc1Cl)C(=O)CO2 nan
20953562 43593 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
CHEMBL1509249 43593 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 7 2.9 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)ncn3n2)cc1 nan
20923188 43760 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
CHEMBL1510719 43760 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 6 2.4 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccccc1 nan
16025766 44035 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
CHEMBL1514065 44035 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 4 5.8 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccccc3Cl)CC2)s1 nan
5206706 44045 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
CHEMBL1514233 44045 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.8 CN(C)c1ccc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)cc1 nan
15988349 44162 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
CHEMBL1515965 44162 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccc(F)cc3)c2n1 nan
4458977 44388 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1518407 44388 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 11 0.7 CCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
15989681 44486 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
CHEMBL1519224 44486 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 7 1 7 4.1 COc1cc2c(=O)n(Cc3ccccc3Cl)c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)c2cc1OC nan
16019398 45198 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1525727 45198 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 0 9 2.6 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Cl)cc4)nnn3c3ccsc23)CC1 nan
16009804 45548 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
CHEMBL1528709 45548 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 7 4.3 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1C nan
2808993 45662 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
CHEMBL1529717 45662 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 0 5 3.4 CCc1nc2ccccc2nc1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 nan
588806 46469 23 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
CHEMBL1537195 46469 23 None -1 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 4 1 4 2.5 Cc1nc(SCCC(=O)O)c2ccccc2n1 nan
2810142 47185 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
CHEMBL1543276 47185 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 5 3.6 O=C(Nc1nc2ccsc2c(=O)s1)c1ccc(Cl)cc1 nan
2158355 47606 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1546597 47606 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 7 0 7 1.6 COCCN(CCOC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
1304353 48285 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
CHEMBL1553391 48285 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 3 5.4 Cc1ccc(-c2sc(C(=O)Nc3ccc(Br)cc3)cc2CC(=O)O)cc1 nan
3725217 48696 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
CHEMBL1557963 48696 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 2 2 6 2.1 CC(C)C1Cc2c(sc3ncnc(NN)c23)CO1 nan
16017731 49480 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
CHEMBL1565042 49480 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 5 1.5 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)NCCc1ccccc1 nan
7184630 51585 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1583340 51585 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1ccccc1CNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
24856176 52148 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
CHEMBL1587934 52148 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 4 3.3 CN(CC(=O)Nc1ccccc1Cl)C(=O)COC(=O)Cc1c(F)cccc1Cl nan
16033298 52408 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1590310 52408 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 5.5 Cc1c(C(=O)NCc2ccc(OC(C)C)cc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16010771 52572 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
CHEMBL1592455 52572 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 6 3.5 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 nan
16029563 52698 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
CHEMBL1594200 52698 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 6 4.2 COc1ccc(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(C)ccc32)cc1Cl nan
18553656 52890 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
CHEMBL1595812 52890 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 9 1.0 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(CC(C)(C)C)nc2n(C)c1=O nan
773677 53522 29 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
CHEMBL1601668 53522 29 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 1 1 4 3.9 Cc1ccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCC4)cc1 nan
1414561 53892 31 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1604975 53892 31 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 5 4.0 C=CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
135693221 54980 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1359119 54980 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1615929 54980 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.7 Oc1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
6476987 55347 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1385494 55347 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL1618897 55347 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(/c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
135502886 121676 24 None -2 4 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
CHEMBL358644 121676 24 None -2 4 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 221 1 2 4 1.1 NC(=S)c1cc2ccc(O)cc2oc1=O nan
24360 203344 106 None -12 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL65 203344 106 None -12 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 6 2.1 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
5359 207709 75 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
CHEMBL956 207709 75 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 4 1 3 3.2 CC(C(=O)O)c1ccc(C(=O)c2cccs2)cc1 nan
2647611 52652 13 None - 1 Human 3.9 pPotency = 3.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
CHEMBL1593590 52652 13 None - 1 Human 3.9 pPotency = 3.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 6 3.0 CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)c1C nan
126054 43937 40 None - 1 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
CHEMBL1512545 43937 40 None - 1 Human 5.9 pPotency = 5.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 11 7 12 -0.0 NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)cc2)cc1 nan
380 1287 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
657378 1287 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
CHEMBL68738 1287 54 None -7413 5 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 4 9 -0.2 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NC1CCCC1 nan
191 13174 59 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
CHEMBL11909 13174 59 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 4 9 -2.0 Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
15988009 19711 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1300978 19711 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
1246444 19758 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
CHEMBL1301318 19758 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 2 8 2.6 COc1cc(OC)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)cc1OC nan
5733367 19796 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
CHEMBL1301612 19796 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 9 1 6 3.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCN3CCOCC3)C2c2ccc(F)cc2)cc1C nan
3207945 19836 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
CHEMBL1302034 19836 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 5 2.9 CCOC(=O)CNC(=O)CSc1nc2c(C)cccc2cc1CC nan
2978035 20062 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
CHEMBL1303768 20062 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 4 1.3 O=C(CN1C(=O)c2ccc(Br)cc2C1=O)NCC1CCCO1 nan
16194904 21227 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
CHEMBL1313100 21227 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)CC1 nan
127136 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549067 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549068 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
1549069 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1314043 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
CHEMBL1556805 21342 16 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 5 0 2 5.0 CC[n+]1c(/C=C/C=C/c2ccc(N(C)C)cc2)sc2ccccc21 nan
3151367 21379 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1314339 21379 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 1.8 CCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
16009645 21465 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
CHEMBL1315511 21465 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 2 5 5.9 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)cc1OCC nan
16009682 21506 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
CHEMBL1315996 21506 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1cccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)c1 nan
16023134 21630 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
CHEMBL1317674 21630 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 6 2.4 CNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)C1 nan
16019581 21665 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1318189 21665 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 3 0 9 2.7 CN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
16017720 21675 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
CHEMBL1318320 21675 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 0 4 3.1 O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 nan
2458272 21698 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
CHEMBL1318506 21698 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3ccc4c(c3)OCCO4)nc2n1 nan
15988341 21731 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
CHEMBL1318769 21731 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 2 5 5.3 COc1ccc(-c2cc(C(=O)NCCc3ccccc3)c3c(-c4ccccc4)[nH]nc3n2)cc1OC nan
3245692 21743 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
CHEMBL1318873 21743 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.3 c1ccc(CCNc2nc3ccccc3n3nnnc23)cc1 nan
16009520 22122 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
CHEMBL1322132 22122 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3ccc(NC(=O)c4ccccc4F)cc3)cc(=O)n12 nan
1003845 22154 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
CHEMBL1322400 22154 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)c(F)c4)sc3n2)c1 nan
1021427 22659 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
CHEMBL1327019 22659 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 2 4 4.5 Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(=O)Nc1ccc(Br)cc1 nan
1386649 23465 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1386650 23465 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1333441 23465 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 5 1 5 4.2 O=C(O)CCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
24503354 23611 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
CHEMBL1334480 23611 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 3 2.5 O=C(c1ccc(S(=O)(=O)Nc2ccccc2F)cc1)N1CCC1 nan
15988003 23701 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
CHEMBL1335235 23701 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)c(F)c3)nnc12 nan
135416637 24088 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
CHEMBL1338446 24088 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 2 7 5.8 Cc1ccc(C)c(NC(=O)CSc2nc(O)c3c(C(F)(F)F)cc(-c4cccs4)nc3n2)c1 nan
1023823 24331 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
CHEMBL1340736 24331 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 4 3.3 NS(=O)(=O)c1c(Sc2ccccc2C(=O)O)ccc2ccccc12 nan
3420063 24482 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
CHEMBL1342030 24482 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 2 7 3.4 COc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)c(OC)c1 nan
2023917 25058 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1346887 25058 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 3 4 4.5 O=C(NC(=S)Nc1ccccc1C(=O)O)c1ccc(-c2ccc(Br)cc2)o1 nan
6145649 25148 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
CHEMBL1347564 25148 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 7 1 6 2.9 N#Cc1nc(/C=C/c2ccccc2)oc1NCCCN1CCOCC1 nan
3099832 25207 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
CHEMBL1348101 25207 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 3.7 Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)cc1 nan
16033268 26056 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
CHEMBL1355268 26056 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1cccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
16004219 26115 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
CHEMBL1356105 26115 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 7 4.6 Brc1ccc(-c2ccc(CNCCSc3nnnn3-c3ccccc3)o2)cc1 nan
16033294 26127 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1356206 26127 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 6 5.1 CCOc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
16018776 26190 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
CHEMBL1357046 26190 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 6 4.8 Cc1cc2c(cc3c(SCC(=O)Nc4cccc(Cl)c4C)nnc(C)n32)o1 nan
16014983 26321 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1358814 26321 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2cccc(C)c2)c(C#N)c(-c2ccccc2)n1 nan
7190674 26690 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
CHEMBL1361981 26690 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1F nan
2138626 26774 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
CHEMBL1362650 26774 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1ccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)cc1 nan
4152428 27029 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 27029 7 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
15988005 27186 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1366276 27186 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 2.6 Cc1ccc(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
15996111 27278 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1367087 27278 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 4 4.9 CCOCCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
659844 27364 14 None -11 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
CHEMBL1367765 27364 14 None -11 3 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 8 3.9 CCCCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OCC)cc2)c1C#N nan
5287091 27392 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
CHEMBL1367954 27392 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 2 4.7 Cc1ccc2nc(/C(C#N)=C/c3cccc(Br)c3)[nH]c2c1 nan
15991106 27422 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
CHEMBL1368193 27422 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 1 5 6.0 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1C nan
3544515 27452 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1368416 27452 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 6 1 9 2.2 O=C(O)CCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
4191572 27521 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
CHEMBL1368980 27521 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 COc1ccccc1Cn1c(=S)[nH]c2ccc(F)cc2c1=O nan
2743471 28463 22 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
CHEMBL1375507 28463 22 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 2 1 4 3.7 CSc1cc(-c2ccc(Cl)cc2)nc(O)c1C#N nan
1175821 28467 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1375543 28467 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 0 10 0.7 CC(C)n1c(SCC(=O)N2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
3241220 28505 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
CHEMBL1375857 28505 6 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 1.4 O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 nan
5733045 28762 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
CHEMBL1378340 28762 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 5 4.5 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2cccc(Cl)c2)cc1 nan
3746307 29285 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1382865 29285 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 1 1 5 3.4 Cn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
2939274 29344 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
CHEMBL1383461 29344 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 7 4.5 CC(C)c1nnc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)s1 nan
16194976 29417 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
CHEMBL1384046 29417 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)CC1 nan
15987888 29460 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29460 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2944910 29535 10 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
CHEMBL1385074 29535 10 None -3 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 6 4.2 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccnc1)c1cc2ccccc2o1 nan
1928929 29787 12 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1387110 29787 12 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 3 2 7 5.5 Nc1c(C(=O)Nc2nc3ccccc3s2)sc2nc(-c3cccs3)ccc12 nan
2237376 29809 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
CHEMBL1387290 29809 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 2 8 3.0 CSc1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
2779879 30193 30 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
CHEMBL1390399 30193 30 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 3 4.1 Cc1c(C(=O)c2ccccc2C(=O)O)sc2ccccc12 nan
5088202 30691 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
CHEMBL1394959 30691 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cccc(C)c4)sc3n2)cc1 nan
16018778 30786 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
CHEMBL1396136 30786 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4ccc(Cl)cc4)nnc(C)n32)o1 nan
15987656 30850 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
CHEMBL1397047 30850 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 12 1 6 5.8 CCOc1ccc(CCNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1OCC nan
16018052 30872 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1397347 30872 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 4 3.8 Cc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
15987604 30891 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
CHEMBL1397611 30891 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1ccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)cc1 nan
866239 30944 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
CHEMBL1398397 30944 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 2.9 Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 nan
15990870 31101 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
CHEMBL1399859 31101 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 2 3 5.3 Cc1ccc(C)c(Nc2cc(C(=O)NC3CCCC3)c3ccccc3n2)c1 nan
20904142 31203 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
CHEMBL1400806 31203 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 0 9 1.3 COc1ccc(N2CCN(C(=O)CCc3nnc4ccc(N5CCOCC5)nn34)CC2)cc1 nan
2859630 32007 19 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
CHEMBL1408014 32007 19 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 0.9 O=C(CN1C(=O)c2cccc3cccc(c23)C1=O)NCCN1CCOCC1 nan
22553366 32056 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
CHEMBL1408318 32056 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 7 1.5 CCOC(=O)C1CCN(C(=O)Cn2c(=O)c3cccn3c3cccnc32)CC1 nan
2911470 32731 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1413736 32731 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 8 3.8 C=CCOc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
663378 32756 8 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
CHEMBL1413946 32756 8 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 3 0 5 3.4 N#CCCSc1ncnc2c1oc1ccccc12 nan
1175547 32841 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
CHEMBL1414657 32841 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 9 2.6 COc1cc(OC)cc(-n2nnnc2SCC(=O)Nc2ccc(C(C)=O)cc2)c1 nan
2152512 32865 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
CHEMBL1414820 32865 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1ccccc1OC nan
16033750 32991 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
CHEMBL1416012 32991 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 3 5.8 CC(C)c1ccc(N2C(=O)N(Cc3ccccc3Cl)c3ccccc3S2(=O)=O)cc1 nan
1138440 33030 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1416338 33030 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 10 1.8 CCCn1c(SCC(=O)c2ccc(OC)c(OC)c2)nc2c1c(=O)n(C)c(=O)n2C nan
135445597 33119 22 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1417116 33119 22 None -5 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 2 1 6 2.5 CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
24892379 33279 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
CHEMBL1418535 33279 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 9 1.7 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3Cl)nc2n(C)c1=O nan
24789790 33325 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
CHEMBL1418824 33325 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 0 8 0.8 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3scc(C)n3c2=O)CC1 nan
5220580 33424 15 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
CHEMBL1419730 33424 15 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 5 4.0 CC(=O)c1sc(NC(=O)COc2ccc(Cl)cc2Cl)nc1C nan
3699048 33429 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
CHEMBL1419826 33429 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 2 6 3.5 Cc1ccc[n+](C2C(c3cccs3)C(C#N)=C([C-](C#N)C#N)NC2(O)c2ccccc2)c1 nan
5790281 33562 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
CHEMBL1420847 33562 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 10 1 7 3.7 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2cccnc2)cc1 nan
2974740 33570 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
CHEMBL1420938 33570 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 4 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3cccs3)nc12 nan
824727 33602 12 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
CHEMBL1421240 33602 12 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 2 0 4 2.2 CCOC(=O)c1cc(Br)c(=O)n2ccccc12 nan
6411582 33707 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
CHEMBL1422131 33707 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 10 2 10 4.3 CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CSc1nnc2c3cc(Br)ccc3n(C)c2n1 nan
4910054 33752 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
CHEMBL1422462 33752 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 9 1.1 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(CCO)CC4)o3)nnc2c2ccccc12 nan
2945586 33883 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
CHEMBL1423531 33883 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.6 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1ccncc1)c1cc2ccccc2o1 nan
614539 33920 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
CHEMBL1423802 33920 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 2 4.7 O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Br)cc2c1OCC2 nan
5928009 34239 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
CHEMBL1426470 34239 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 9 -0.1 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CCC(C(N)=O)CC3)nc12 nan
20957179 34335 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1427296 34335 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 9 0.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
2376694 34340 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
CHEMBL1427343 34340 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 8 0.5 Cn1c(N)c(C(=O)CSc2nc3ccccc3[nH]2)c(=O)n(C)c1=O nan
20970067 34565 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
CHEMBL1429318 34565 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 9 1 8 2.4 COc1ccc(OC)c(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)c1 nan
2950264 34584 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
CHEMBL1429474 34584 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 6 2.6 O=C(CSc1ncnc2sc3c(c12)CCC3)NCC1CCCO1 nan
135436945 35082 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
CHEMBL1433539 35082 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 2 4 5.5 Cc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c(C)c1 nan
16030485 35183 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1435046 35183 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
1775325 35242 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
CHEMBL1435817 35242 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 0 6 4.3 COc1ccc(CN2COc3ccc4c(oc(=O)c5ccccc54)c3C2)cc1OC nan
135433305 35747 1 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1440872 35747 1 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 3 8 1.3 CNC(=O)NC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
2816654 36388 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
CHEMBL1446784 36388 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 1 6 1.9 CCOC(=O)N1CCc2c(sc3ncnc(O)c23)C1 nan
749058 36452 28 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1447245 36452 28 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 5 4.8 O=c1c2c(-c3cccs3)csc2[nH]c(=S)n1-c1ccccc1 nan
739884 36546 81 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
CHEMBL1448105 36546 81 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 1 1 2 3.9 O=C(O)c1sc2cc(Cl)ccc2c1Cl nan
16033236 36727 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1449453 36727 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2ccccc2Cl)sc2ncnc(N(C)C3CCCCC3)c12 nan
2572725 36889 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
CHEMBL1450791 36889 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 6 2.8 Cc1cc(C(=O)OCC(=O)c2ccc(Br)s2)no1 nan
2787753 37108 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
CHEMBL1452524 37108 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 4 3 8 0.6 CC(C)OC(=O)C(C)Nc1nnc(S)nc1O nan
4984225 37587 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
CHEMBL1456558 37587 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.8 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)Nc2cccnc2Cl)cc1 nan
764734 37959 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
CHEMBL1459809 37959 28 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 5 3.6 C=CCn1c(=S)[nH]c2scc(-c3ccco3)c2c1=O nan
2822524 38059 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
CHEMBL1460605 38059 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 5 3.5 CCOC(=O)c1c(SC)nc2c(Cl)cccc2c1O nan
2973900 38381 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
CHEMBL1463377 38381 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 3 4.9 Cc1cc(Br)cc2c(C(=O)NCC3CCCO3)cc(-c3ccccc3)nc12 nan
5637963 38461 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
CHEMBL1464025 38461 5 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 0 5 3.7 CCOC(=O)/C(C#N)=C/c1cc2ccccc2nc1N1CCCCC1 nan
1005162 38505 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
CHEMBL1464360 38505 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.9 N#Cc1ccc(-c2ccc(F)cc2)nc1SCC(=O)Nc1sc2c(c1C#N)CCC2 nan
2087618 38519 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
CHEMBL1464466 38519 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 6 2.8 CCOc1cc(C=O)ccc1OCc1cc(=O)n2cc(C)ccc2n1 nan
20904553 38730 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
CHEMBL1466036 38730 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.8 CC(NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12)c1ccccc1 nan
20923124 38732 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1466048 38732 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
16681736 38900 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
CHEMBL1467358 38900 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 2 5 3.1 C1COCCO1.O=C(Nc1cccc2ccccc12)C(=O)C1C(=O)Nc2ccccc21 nan
2788467 38942 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1467713 38942 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 2 6 3.4 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
4224805 38970 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
CHEMBL1468056 38970 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 2.0 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCCCC3)c(=O)c2c1C nan
22334123 39118 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
CHEMBL1469191 39118 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1OC nan
5016620 39574 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
CHEMBL1473482 39574 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 5 3.5 COc1ccc(-c2cc(C(=O)Nc3ccc(C#N)cc3)no2)cc1 nan
775363 39715 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
CHEMBL1475499 39715 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 7 0.7 Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C nan
16009659 39774 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1476377 39774 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 7 4.1 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
5730013 39823 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
CHEMBL1476964 39823 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 4.0 CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)Nc1nnc(C(C)C)s1 nan
1782877 39883 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
CHEMBL1477517 39883 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 2 6 3.9 COc1ccc(-c2cc3ccc(OCC(=O)NCC4CCC(C(=O)O)CC4)cc3oc2=O)cc1 nan
20957466 40135 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1479770 40135 1 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 7 1.7 CC1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
5378436 40137 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
CHEMBL1479779 40137 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 6 1.4 Cn1c(=O)[nH]c2nnc(-c3ccc(Cl)c(Cl)c3)nc2c1=O nan
7207545 40945 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
CHEMBL1486756 40945 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)cc3F)nn2)s1 nan
974443 41165 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1488414 41165 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 7 0.5 COc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
250222 41204 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
CHEMBL1488698 41204 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 1 3 2.9 O=C1c2ccccc2C(O)(c2ccccc2)N1c1ccncc1 nan
2158358 41254 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1489076 41254 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 2 0 7 1.8 CCOC(=O)N1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
4000951 41388 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1490219 41388 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 11 1.8 Cn1c(N)c(C(=O)CSc2nn(-c3ccc(F)cc3)c(=S)s2)c(=O)n(C)c1=O nan
5310114 41448 3 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
CHEMBL1490578 41448 3 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 7 2.1 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)O nan
135436946 41458 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
CHEMBL1490651 41458 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 2 5 5.6 CSc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)cc1 nan
2857238 41627 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
CHEMBL1491753 41627 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 2 3 4.3 CC(Oc1ccccc1)C(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 nan
3913191 41792 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
CHEMBL1493081 41792 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 2 6 2.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(O)nc2)c1 nan
16009715 41950 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1494680 41950 11 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
252183 42123 18 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
CHEMBL1496411 42123 18 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 3 3 7 -0.3 O=C1NC(=O)C(=NNc2ccc([N+](=O)[O-])cc2)C(=O)N1 nan
4023603 42607 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
4921719 42607 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
CHEMBL1500596 42607 10 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 3.5 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)c2ccccc21 nan
2100904 43121 5 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
CHEMBL1505221 43121 5 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 6 3.9 Cc1nn(CCc2nn[nH]n2)c2nc(-c3ccc(Br)cc3)cc(C(F)(F)F)c12 nan
1103129 43551 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
CHEMBL1508887 43551 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 1 3 4.1 O=C(O)c1cccc(N2C(=O)c3cc4cccc(Br)c4cc3C2=O)c1 nan
15990473 43972 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1513016 43972 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.6 CCOc1ccccc1NC(=O)c1cn(C2CCCCC2)c(=O)c2c1c1ccccc1n2C nan
3858365 43992 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1513368 43992 13 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 6 5.7 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
16018934 44017 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
CHEMBL1513698 44017 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 5.9 CCc1nnc(SCc2ccc(F)cc2Cl)c2cc3sc(C)cc3n12 nan
16025722 44169 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
CHEMBL1516031 44169 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 6 6.2 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3Cl)s1)C2 nan
5110655 44539 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1519696 44539 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 3.8 Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2161841 44886 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
CHEMBL1522742 44886 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.5 Cc1nc(SCC(=O)N2CC(=O)Nc3ccccc32)nc(C)c1C nan
1238361 45018 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL1523965 45018 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 1 5 6.5 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(C(F)(F)F)c1 nan
20904542 45154 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
CHEMBL1525378 45154 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 1.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccco3)nnc12 nan
2592811 45197 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
CHEMBL1525704 45197 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 4 0 7 2.5 O=[N+]([O-])c1cc2c(c(CSc3ncccn3)c1)OCOC2 nan
6078768 45210 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
CHEMBL1525799 45210 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 5 4.9 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(C)cc2)c(C)c1 nan
1147569 45218 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1525877 45218 17 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 7 3.6 COc1cc(SC)ccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
4181953 45340 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
CHEMBL1526825 45340 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 1 0 3 3.9 Cn1/c(=N\C(=O)c2ccc(F)cc2)sc2cc(Br)ccc21 nan
5380406 45357 85 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
CHEMBL1526978 45357 85 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 0 1 3 2.7 O=c1oc2cc(O)ccc2c2ccccc12 nan
5641185 45568 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
CHEMBL1528897 45568 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 8 0.1 Cc1c(C(=O)NNc2cc(=O)n(C)c(=O)n2C)cccc1[N+](=O)[O-] nan
1016791 45621 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1529358 45621 13 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 3 5.0 CC(C)c1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
7411882 45770 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
CHEMBL1530681 45770 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)cc1 nan
16017598 45891 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
CHEMBL1531718 45891 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)c1 nan
16025817 45983 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1532579 45983 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 1 5 5.3 CCOc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
20939726 46063 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
CHEMBL1533261 46063 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 0 7 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCOc2ccccc21 nan
16033292 46213 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1534658 46213 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 6 5.4 CSc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
135521540 46349 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
CHEMBL1536204 46349 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 2 6 4.5 O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc(-c2nc3ccccc3s2)c(O)c1 nan
2729862 46931 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1541137 46931 5 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 2 8 0.2 Cc1ccc(NCC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
2487501 46978 30 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
CHEMBL1541468 46978 30 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 2 6 1.3 Oc1nc2ccccc2n2c(S)nnc12 nan
16194809 47323 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
CHEMBL1544280 47323 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1nnc2ccc(-c3ccccn3)nn12)NCC1CCCO1 nan
1866349 47443 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47443 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47443 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47443 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
15988305 48240 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1552888 48240 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 2.5 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
1327631 48403 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
CHEMBL1555206 48403 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CCc1ccc(OCC(=O)Nc2ccc3oc(-c4ccc(OC)cc4)nc3c2)cc1 nan
16033300 48416 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1555399 48416 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 5.3 CCc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
20970028 48496 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
CHEMBL1556192 48496 0 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 5 1.7 CC(C)NS(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
5202629 48714 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1558116 48714 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 7 2.4 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
7411867 49014 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
CHEMBL1560888 49014 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 0 4 4.3 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2)CC1 nan
20923142 49200 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
CHEMBL1562552 49200 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 1.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC(C)C nan
3505859 49202 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
CHEMBL1562557 49202 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 8 2.3 CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)Cn2cnc3cc([N+](=O)[O-])ccc3c2=O)c1 nan
7524261 49302 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1563485 49302 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 2.6 CCS(=O)(=O)Nc1cccc(-c2ccc3nnc(-c4cccnc4)n3n2)c1 nan
5389817 49472 8 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
CHEMBL1564945 49472 8 None 1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 1 6 3.2 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(CCCOC)C23C(=O)N(C)c2ccccc23)cc1 nan
1111955 49487 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
CHEMBL1565140 49487 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 4.1 COc1ccc(-n2nc3ccc(NC(=O)COc4ccc(C)c(C)c4)cc3n2)cc1 nan
15988272 49822 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
CHEMBL1567650 49822 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 0 9 2.0 COC(=O)c1ccc(OC)c(Cn2c(=O)n(-c3ccc(C)cc3)c(=O)c3c2cnn3C)c1 nan
15991345 50018 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
CHEMBL1569335 50018 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 0 5 5.1 CSc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2ccc(C)cn2)cc1 nan
15988962 50305 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1571921 50305 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCN(CCC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
2483422 50809 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
CHEMBL1576699 50809 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 6 1.1 Cn1c(CCC(=O)OCC(=O)NCC(F)(F)F)nc(=O)c2ccccc21 nan
5070065 51287 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
CHEMBL1580853 51287 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 1 8 5.1 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(C)=O)s2)c1 nan
4295307 51361 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1581437 51361 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1ccccc1C1C(C(=O)c2cc3ccccc3o2)=C(O)C(=O)N1c1cc(C)on1 nan
4808157 51554 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1583111 51554 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 0.5 COc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
6530035 52065 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
CHEMBL1587266 52065 3 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 2.6 CCN(CC)S(=O)(=O)c1ccc(C(=O)NCCN2C(=O)S/C(=C\c3cccnc3)C2=O)cc1 nan
15988968 52468 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
CHEMBL1591154 52468 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)c(OC)c1 nan
16024517 52485 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1591352 52485 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 5.0 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C(C)C)cc3)c3nc(C)ccc3c2=O)cc1 nan
16018826 52549 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1592153 52549 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 6 4.2 CCc1cccc(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16010502 52629 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1593224 52629 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 2 0 4 4.4 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccc2F)CC1 nan
1191851 53172 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
CHEMBL1598484 53172 11 None -1 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.0 CCc1ccccc1NC(=O)COc1ccc2oc(-c3ccc(OC)cc3)cc(=O)c2c1 nan
20888741 53363 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
CHEMBL1600180 53363 14 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 7 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCCC2)s1 nan
16018860 53570 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
CHEMBL1602197 53570 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 6 4.6 Cc1ccc(NC(=O)CSc2nnc(C)n3c2cc2sccc23)c(C)c1 nan
135460554 53809 7 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
CHEMBL1604187 53809 7 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 7 2.5 CC(=O)CSc1nc(O)c(C#N)c(-c2cccs2)n1 nan
16194880 53888 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
CHEMBL1604935 53888 9 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 8 2.2 CCC(Sc1ccc2nnc(-c3cccnc3)n2n1)C(=O)OC nan
2939815 54163 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1607085 54163 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2ccccc2n2c(SCC(=O)NCC3CCCO3)nnc12 nan
16017570 54527 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
CHEMBL1610070 54527 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 6 3.3 CN(Cc1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2cccc(Cl)c2)s1 nan
7184628 54631 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
CHEMBL1611000 54631 7 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccccc3)nnc12 nan
20957175 54923 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
CHEMBL1613668 54923 6 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 0 8 1.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)N1CCCCC1 nan
11077 55036 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1353221 55036 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
CHEMBL1616414 55036 35 None -4 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 0 1 4 1.2 O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1 nan
686692 55056 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1309275 55056 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
CHEMBL1616571 55056 10 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 8 -0.5 Cn1c(=O)c2c(ncn2CCCC(=N)N2CCOCC2)n(C)c1=O nan
694704 55344 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1373811 55344 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1618856 55344 58 None -2 2 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 3 3.8 O=C(O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
3246720 55664 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1445386 55664 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
CHEMBL1621717 55664 2 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 3 8 1.0 CC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(NC(=O)CN)cccc3nc2-1 nan
135439671 72201 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
CHEMBL1980641 72201 8 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 2 9 0.1 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/c2c[nH]nc2-c2ccc(F)cc2)n(C)c1=O nan
6187702 72773 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
CHEMBL1999641 72773 4 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 6 2.6 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1ccc(N2CCOCC2)cc1 nan
2058613 108368 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
CHEMBL3198223 108368 11 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 9 3.2 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1cccc(OC)c1 nan
2947382 176316 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
CHEMBL459529 176316 12 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 1 5 1.8 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)C2CCCO2)c1 nan
3151452 199584 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL592554 199584 16 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 8 1.8 COCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3cccc(C)c3nc21 nan
3159270 201604 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
CHEMBL605753 201604 15 None - 1 Human 4.9 pPotency = 4.9 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 0 5 2.6 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCN(C)C)CC2 nan
9687 185335 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1522836 185335 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL485980 185335 25 None 1 4 Human 6.8 pPotency = 6.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.7 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2COP(=O)(O)O[C@H]2[C@H]1OC(=O)CCC nan
16682183 25346 1 None - 1 Human 5.8 pPotency = 5.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
CHEMBL1349353 25346 1 None - 1 Human 5.8 pPotency = 5.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 2 0 5 4.6 CC(C)C(=O)N1CCC2(CC1)Oc1ccc(F)cc1C(=O)C21CC(c2ccc(Cl)cc2)=NO1 nan
123807 871 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
374 871 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
379 871 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
CHEMBL284969 871 54 None -2630 7 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 4 9 0.4 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2NC1CCCC1 nan
2099 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
123683 3121 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
422 3121 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
CHEMBL119709 3121 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
DB05511 3121 63 None -33884 5 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 4 9 0.4 CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I nan
2808307 10385 5 None -9 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
CHEMBL1162415 10385 5 None -9 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 4 4.2 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)c1ccccc1C(=O)O nan
16019490 11000 5 None -8 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
CHEMBL1173709 11000 5 None -8 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)c1 nan
2729861 20406 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1306604 20406 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 8 0.0 Cn1c(=O)c2c(ncn2CC(O)CNc2ccc(F)cc2)n(C)c1=O nan
713572 20509 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1307433 20509 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 0 2 4 3.0 CC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
20884214 20796 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
CHEMBL1309746 20796 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 1.4 CCC(C(=O)NCCN1CCOCC1)n1nc(C)n2c(cc3sccc32)c1=O nan
1831123 20849 8 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
CHEMBL1310276 20849 8 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 3 1 7 5.2 Cc1nc2c(sc3nc(N4CCOCC4)c4c(c32)CC(C)(C)OC4)c(-c2ccccc2)c1C(=O)O nan
16194788 21036 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
CHEMBL1311747 21036 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.2 O=C(CSc1nnc2ccc(-c3ccccc3)nn12)NCC1CCCO1 nan
2820129 21134 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
CHEMBL1312452 21134 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 2 4 2.2 CSc1sc(C(=O)NNC(C)=O)c2c1C=CCC2 nan
622563 21207 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
CHEMBL1312974 21207 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 0 4 3.1 CN1c2ccc(C=O)c3c(C=O)ccc(c23)N(C)C1(C)C nan
4584575 21274 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
CHEMBL1313487 21274 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 2 5 3.7 CC(C)N=C(S)n1cc(C(=O)c2cc(Cl)cc(Cl)c2O)cn1 nan
16029652 21503 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
CHEMBL1315982 21503 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 6 5.0 CCOc1ccc(NC(=O)c2sc3nc(-c4ccc(OC)cc4)cn3c2C)cc1 nan
1116235 21563 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
CHEMBL1316844 21563 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 9 0.7 COc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)cc1Cl nan
16030395 21584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1317102 21584 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 4 4.5 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16018828 21589 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
CHEMBL1317182 21589 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.1 Cc1ccc(NC(=O)CSc2nncn3c2cc2sccc23)cc1F nan
16018832 21619 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1317561 21619 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.3 Cc1ccc(C)c(NC(=O)CSc2nncn3c2cc2sccc23)c1 nan
16025821 21656 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318005 21656 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 1 5 4.9 CN(C)c1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
1482206 21733 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
CHEMBL1318777 21733 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 5 2.1 CS(=O)(=O)c1ccc(-c2cn3cc(C(=O)O)ccc3n2)cc1 nan
1115262 21754 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1318956 21754 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 2 4 5.5 O=C(O)c1ccc(Nc2nc(-c3ccccc3)c3cc(Br)ccc3n2)cc1 nan
16025794 21756 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1318960 21756 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.2 Cc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
16021547 21770 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
CHEMBL1319081 21770 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 6 2 8 1.8 NS(=O)(=O)c1ccc(CCNC(=O)C2CCN(c3ncnc4c3nc3n4CCCCC3)CC2)cc1 nan
6287803 21775 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
CHEMBL1319132 21775 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 6 4.6 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(Br)cc3)ccc2O1 nan
15988299 21798 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
CHEMBL1319322 21798 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
3152547 21984 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
CHEMBL1320921 21984 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 3.2 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1F)c1ccco1 nan
829953 22096 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1321896 22096 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 5 2.4 CCN(CC)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
3147388 22262 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
CHEMBL1323473 22262 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 1 4 2.9 Cc1cc(SCC(=O)NCC2CCCO2)nc2ccccc12 nan
3154196 22363 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
CHEMBL1324245 22363 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 8 -0.1 CN(CC(O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 nan
16019851 22424 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
CHEMBL1324764 22424 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 11 1 9 1.9 CCOCCCNC(=O)CCc1nnc2ccc(N3CCN(c4cccc(OC)c4)CC3)nn12 nan
16018924 22449 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
CHEMBL1324960 22449 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 0 5 5.2 CCc1nnc(SCc2cccc(F)c2)c2cc3sc(C)cc3n12 nan
4156222 22508 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
CHEMBL1325527 22508 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 6 2.5 O=C(c1cccc([N+](=O)[O-])c1)N1CCCN(C(=O)c2cccc([N+](=O)[O-])c2)CC1 nan
16012102 22650 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
CHEMBL1326931 22650 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
342695 22843 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
CHEMBL1328402 22843 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 8 0.6 Cn1c([N+](=O)[O-])cnc1N1CCN(c2nncs2)C1=O nan
5048043 22868 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1328648 22868 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
16195662 22960 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
CHEMBL1329498 22960 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 9 1.6 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(-c4ccncc4)n3n2)CC1 nan
15988282 22997 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1329775 22997 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.0 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(F)cc3)nnc12 nan
753118 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
15989826 23306 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
CHEMBL1332222 23306 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 1 6 3.2 Cc1ccc2nc(NCc3ccccc3Cl)c3nnnn3c2c1 nan
7120050 23903 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
CHEMBL1336910 23903 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 4 3.9 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccc(F)cc1 nan
2997990 23941 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
CHEMBL1337270 23941 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 10 -0.2 Cc1cc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)n1C nan
5827230 24020 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1338023 24020 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 9 3.4 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
4385163 24201 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1339561 24201 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 2 4 4.5 COc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
8030040 24374 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
CHEMBL1341144 24374 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 2 5 3.2 O=C(NCCNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1)c1cnccn1 nan
661441 24778 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1344527 24778 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
CHEMBL1530959 24778 7 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 3 2.8 CC(Sc1ccc2ccccc2n1)C(=O)O nan
865623 24783 2 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
CHEMBL1344555 24783 2 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 3 0 5 3.5 CN(C)c1ccc(-c2nnc(-c3cccs3)o2)cc1 nan
2937580 24900 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
CHEMBL1345579 24900 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 5 3.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(CC3CCCO3)C2c2ccccc2F)o1 nan
1375907 25040 6 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1346739 25040 6 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 0 7 1.4 CCOC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
5037672 25097 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
CHEMBL1347181 25097 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 8 1.4 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cn2ccccc2n1 nan
3748480 25163 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1347701 25163 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 7 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
6463240 25185 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1347878 25185 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 9 0.6 CC(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
4046369 25322 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
CHEMBL1349141 25322 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 7 1.8 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCCC4)c3)nc2n1 nan
5810234 25357 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1349428 25357 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
664152 25403 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
CHEMBL1349799 25403 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 6 3.1 Cc1nc(SCC(=O)NCC2CCCO2)c2oc3ccccc3c2n1 nan
4648816 25445 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1350189 25445 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 8 2.4 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
2081076 25476 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
CHEMBL1350435 25476 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 1 5 3.3 O=c1c2c3c(sc2[nH]c(=S)n1Cc1ccco1)CCC3 nan
6618816 25541 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1351035 25541 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
3117452 25546 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
CHEMBL1351071 25546 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 3 1.4 Cc1c2ccccc2cc[n+]1CCCS(=O)(=O)[O-] nan
5809890 25670 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1352143 25670 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 1 6 3.8 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
24794131 25682 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
CHEMBL1352219 25682 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 0 8 2.7 CSc1ccccc1OCc1cc(C(=O)N2CCN(c3ncccn3)CC2)no1 nan
20903685 25729 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
CHEMBL1352523 25729 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 0 8 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCC(C)CC4)nn23)CC1 nan
2322442 25768 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
CHEMBL1352855 25768 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 5 3.3 Cc1noc(NS(=O)(=O)c2ccc(N3Cc4ccccc4C3=O)cc2)c1C nan
135490313 25916 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
CHEMBL1353870 25916 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -0.6 Cc1cc(O)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 nan
20923143 26028 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1354972 26028 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 6 1.6 CCCNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1116268 26042 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1355136 26042 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 9 -0.1 COC(=O)c1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
1003440 26158 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1356669 26158 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 2 5 5.9 Nc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)sc2nc(-c3cccs3)ccc12 nan
16024861 26238 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1357771 26238 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 4 3.0 CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
25162722 26309 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
CHEMBL1358718 26309 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 9 1.4 CCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nncn1C nan
4312795 26470 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
CHEMBL1360045 26470 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 4 2.2 CC(Sc1cnc2ccccc2n1)C(=O)O nan
3704657 26482 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
CHEMBL1360163 26482 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 6 3.2 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2ncccn2)cc1 nan
24000844 26498 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
CHEMBL1360279 26498 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.9 Cn1c2ccccc2c2nnc(SCC(=O)Nc3cccc(C(=O)O)c3)nc21 nan
791500 26520 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
CHEMBL1360458 26520 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 5 3.4 CCOC(=O)c1c(C)nc(S)c(C#N)c1-c1ccccc1 nan
3178481 26699 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1362095 26699 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
5309057 26780 2 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
CHEMBL1362711 26780 2 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 5 3.7 O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCN(c2ccccn2)CC1 nan
16022478 26801 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
CHEMBL1362937 26801 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 9 4.3 COc1cccc(NC(=O)c2ccc3c(=O)n4nc(Nc5ccccc5OC)sc4nc3c2)c1 nan
20917857 27093 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
CHEMBL1365432 27093 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.4 Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)o1 nan
2999882 27271 21 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
CHEMBL1367025 27271 21 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 7 1 5 2.9 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1ccccc1 nan
1914729 27359 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
CHEMBL1367732 27359 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 11 1 3 4.7 CC(=O)c1ccc(CCCCCCCCCC(=O)O)s1 nan
3820161 27410 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
CHEMBL1368082 27410 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccccc2F)o1 nan
135419062 27457 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
CHEMBL1368444 27457 6 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 7 4.5 N#Cc1c(O)nc(SCC(=O)c2ccc(Br)cc2)nc1-c1cccs1 nan
3154099 27575 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1369329 27575 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 4.1 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
2443232 27811 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
CHEMBL1370986 27811 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 1 5 6.4 O=C(COC(=O)c1cc(-c2ccccc2Cl)nc2ccccc12)Nc1ncc(C(F)(F)F)cc1Cl nan
22548207 27843 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
CHEMBL1371227 27843 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 0.8 CCOC(=O)CNC(=O)Cn1cnc2c(oc3ccccc32)c1=O nan
663879 28271 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
CHEMBL1374204 28271 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 9 1 7 4.2 Cc1ccc(C(=O)C2=C(O)C(=O)N(CCCn3ccnc3)C2c2ccc(OC(C)C)cc2)o1 nan
20917681 28276 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
CHEMBL1374225 28276 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 2.0 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)s1 nan
4855374 28551 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
CHEMBL1376372 28551 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 0 10 -0.3 CN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1(C#N)CCCCC1 nan
20917816 28988 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
CHEMBL1380363 28988 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 0 5 2.4 CC1CCN(S(=O)(=O)c2cc(F)ccc2CN2C(=O)c3cccnc3C2=O)CC1 nan
661999 29073 14 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
CHEMBL1380975 29073 14 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
4342649 29186 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
5027943 29186 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
CHEMBL1381980 29186 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(F)c1)c1cc2ccccc2o1 nan
135431552 29254 10 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
CHEMBL1382616 29254 10 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 6 4.7 N#Cc1c(O)nc(SCc2ccc(Cl)cc2)nc1-c1cccs1 nan
921583 29647 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1386089 29647 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 1 1 3 4.3 Sc1nc(-c2ccccc2)nc2ccc(Br)cc12 nan
5428525 29968 25 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
CHEMBL1388510 29968 25 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 1 5 1.8 COC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
5824610 30016 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1388949 30016 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 7 1 5 3.1 CN(C)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
16194879 30364 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
CHEMBL1391905 30364 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c(OC)c1 nan
1256976 30425 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
CHEMBL1392432 30425 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 2 5 3.6 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccc(Br)cc23)cc1 nan
7222624 30720 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
CHEMBL1395178 30720 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 6 4.2 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(F)c(F)c3)nn2)s1 nan
16018363 30744 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
CHEMBL1395439 30744 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 6 5.5 COc1ccc(NC(=O)c2ccc3c(c2)sc2nc(-c4ccc(OC)cc4)cn23)cc1 nan
15990211 30895 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
CHEMBL1397707 30895 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 6 3.1 Fc1ccc(CNc2nc3ccc(Cl)cc3n3nnnc23)cc1 nan
7151328 30956 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
CHEMBL1398475 30956 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 5 3.1 CCS(=O)(=O)Nc1ccc(-c2cn3c(C)csc3n2)cc1 nan
20939725 31058 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
CHEMBL1399426 31058 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 0 7 2.9 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)Oc2ccccc21 nan
16452548 31309 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
CHEMBL1401713 31309 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)c1 nan
3709623 31419 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
CHEMBL1402642 31419 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)o1 nan
5212778 31447 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
661982 31447 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
CHEMBL1402874 31447 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 6 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccn1 nan
3152754 31530 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
CHEMBL1403767 31530 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 5 4.2 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccs1)c1ccco1 nan
2816622 31607 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
CHEMBL1404356 31607 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 4.8 COc1ccc(-n2c(=S)[nH]c3sc(-c4ccccc4)cc3c2=O)c(OC)c1 nan
7245568 31733 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1405733 31733 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 2.2 COc1ccc(NC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4184357 31751 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
CHEMBL1405932 31751 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 6 1 9 4.3 O=C(O)c1ccc(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)cc1 nan
757946 31987 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
CHEMBL1407788 31987 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 2 4.7 Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O nan
3160259 32060 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
CHEMBL1408356 32060 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 7 2.2 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCC(C)O nan
1071246 32133 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1408937 32133 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 8 0.6 CCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
744304 32168 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
CHEMBL1409203 32168 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 2 4 2.4 COc1ccc2[nH]c3c(S)ncnc3c2c1 nan
3240452 32170 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
CHEMBL1409223 32170 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 0.4 O=C(Cn1cnc2c(nnn2-c2ccc(F)cc2)c1=O)NCC1CCCO1 nan
15989908 32276 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1410062 32276 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 0 7 2.2 CCOC(=O)CSc1nc2ccccc2n2c(C)nnc12 nan
20923121 32316 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
CHEMBL1410345 32316 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 2.0 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1 nan
3998353 32509 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
CHEMBL1412011 32509 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 8 1.0 Cc1cc(C)n2nc(C(=O)Nc3cccc(S(=O)(=O)N4CCOCC4)c3)nc2n1 nan
16034646 32602 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
CHEMBL1412706 32602 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 7 3.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(Cl)cc3)nnc12 nan
1145396 32700 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
5026856 32700 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1413474 32700 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 3 1 4 4.4 O=C(O)C1CCN(c2nc(-c3ccccc3)c3cc(Br)ccc3n2)CC1 nan
652152 32843 19 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
CHEMBL1414671 32843 19 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 2 1 3 2.7 COc1ccc2c(Cl)c(C(N)=O)sc2c1 nan
1004109 32961 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
CHEMBL1415733 32961 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 2 4 5.4 Cc1ccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1F nan
22334931 33021 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
CHEMBL1416271 33021 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 4 3.5 O=C(O)CSc1nc2ccccc2nc1Cc1ccccc1F nan
3953394 33126 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1417177 33126 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 8 1.5 O=C(CSc1nnc2ccccn12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
24687828 33141 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
CHEMBL1417257 33141 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 0 11 -0.1 COc1ccc(C(=O)COC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1 nan
7184635 33394 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1419486 33394 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 2.3 COc1cccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
4796292 33439 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
CHEMBL1419907 33439 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 6 1.1 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 nan
744542 33462 37 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
CHEMBL1420044 33462 37 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 3 3.4 Cc1cc(SCCC(=O)O)nc2c(C)cccc12 nan
3789487 33532 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
CHEMBL1420588 33532 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 3.0 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(F)cc1)c1ccco1 nan
1473006 33586 15 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
CHEMBL1421084 33586 15 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 1 0 2 4.1 COc1cc2cc(Br)cc(Br)c2nc1C nan
22421602 33641 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
CHEMBL1421499 33641 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 9 2 8 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1 nan
20957484 33648 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
CHEMBL1421579 33648 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 9 1.3 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)CC1 nan
7190683 33663 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1421703 33663 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
7190642 33806 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1422914 33806 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1cccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
741274 34036 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
CHEMBL1424800 34036 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 0 7 0.6 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCC3 nan
3816425 34122 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1425600 34122 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
7299201 34130 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
CHEMBL1425693 34130 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.6 Cc1cccc(C)c1Nc1c(-c2ccc(N3CCOCC3)cc2)nc2cnccn12 nan
5739077 34306 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1427088 34306 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 8 2.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3830309 34439 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
CHEMBL1428271 34439 18 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 6 4.7 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1)c1cc2ccccc2o1 nan
20903609 34690 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
CHEMBL1430241 34690 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 9 1 10 3.0 COc1cc(NC(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)cc(OC)c1 nan
990446 34717 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
CHEMBL1430459 34717 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 9 2.1 COc1cccc(-n2nc3c(-n4ncc(C#N)c4N)nnc(C)c3c2C)c1 nan
2809114 34866 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
CHEMBL1431741 34866 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 4 4.7 CC(=O)c1sc(-c2ccccc2)cc1NS(=O)(=O)c1ccc(C)cc1 nan
4968705 35018 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1433054 35018 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 0 10 -0.5 CN(C)S(=O)(=O)c1ccc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
16019549 35112 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
CHEMBL1433993 35112 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 3 0 9 2.8 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(N1CCOCC1)c1sccc12 nan
20885693 35220 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
CHEMBL1435443 35220 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 1 6 2.0 Cc1nn(CCCC(=O)NCCc2ccc(Cl)cc2)c(=O)c2nccn12 nan
4380857 35226 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
CHEMBL1435516 35226 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1c(CN(C)C(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cnn1C nan
5066674 35238 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
CHEMBL1435676 35238 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 2.7 COC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc3c2N(C(C)=O)CC3)cc(C(=O)OC)c1 nan
3993922 35304 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1436555 35304 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 7 1.2 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2ccsc2n1 nan
16018682 35321 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
CHEMBL1436824 35321 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.1 CCc1ccccc1NC(=O)CSc1nncn2c1cc1oc(C)cc12 nan
16026770 35342 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
CHEMBL1437080 35342 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 7 1.7 Cc1csc2nc(COC(=O)CNC(=O)c3ccc(F)cc3)cc(=O)n12 nan
90660425 35467 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
CHEMBL1438291 35467 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 5 5.1 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccccc2F)cc1C nan
663438 35636 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
CHEMBL1439795 35636 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 6 1.4 O=S(=O)(c1cccc(-c2cn3cccnc3n2)c1)N1CCOCC1 nan
135544645 35645 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
CHEMBL1439904 35645 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 7 3.7 N#Cc1c(O)nc(SCC(=O)Nc2cccc(Cl)c2)nc1-c1ccco1 nan
3363660 35785 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
4976974 35785 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
CHEMBL1441169 35785 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 7 3.3 CCN1C(=O)C2(C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN2CCOCC2)c2ccccc21 nan
2854626 35793 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
CHEMBL1441242 35793 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 5 5.1 CC(=O)C1=C(C)NC(SCC(=O)c2ccc(Cl)cc2)=C(C#N)C1CC(C)C nan
20957185 35948 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
CHEMBL1442625 35948 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 1 8 1.9 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccc(F)cc1 nan
812443 36142 47 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1444467 36142 47 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 2 1 4 3.2 C=CCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
20923160 36144 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1444486 36144 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 8 1 7 2.4 COc1ccccc1CNS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
16745544 36522 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
CHEMBL1447877 36522 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 2 1 5 2.5 COc1ccc(C2=CC3=C(Br)C(=O)C(C)(O)C(=O)C3=CO2)cc1 nan
2376086 36586 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1448425 36586 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 5 2.6 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
16745680 36736 0 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
CHEMBL1449527 36736 0 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 0 7 5.7 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1CC(C)C nan
16018684 36737 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
CHEMBL1449543 36737 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 4.4 Cc1cc(C)c(NC(=O)CSc2nncn3c2cc2oc(C)cc23)c(C)c1 nan
1094076 36750 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
CHEMBL1449615 36750 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 6 3.0 CC(=O)c1ccc(Nc2nc(=O)c3cccnc3s2)cc1 nan
3514089 36895 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1450861 36895 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
6619005 37113 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
CHEMBL1452549 37113 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 5 1 7 4.4 Cc1c(N2C(=O)C(O)=C(C(=O)c3ccc(Br)cc3)C2c2cccnc2)c(=O)n(-c2ccccc2)n1C nan
16194575 37290 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
CHEMBL1453968 37290 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)s1 nan
3178522 37355 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1454485 37355 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 0 9 0.2 CCCCn1c(SCC(=O)N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
2613266 37427 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
CHEMBL1455089 37427 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 0 8 2.8 O=[N+]([O-])c1cc2c(c(CSc3nnc4ccccn34)c1)OCOC2 nan
1084466 37539 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
CHEMBL1456125 37539 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 6 2.5 COc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
20885676 37591 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1456629 37591 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 6 1.6 Cc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
3715206 37600 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
CHEMBL1456701 37600 22 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 5 3.9 CCn1c(=S)[nH]c2scc(-c3cccs3)c2c1=O nan
3252203 37753 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
CHEMBL1457998 37753 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.2 O=C(CSc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl nan
2939635 37856 38 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
CHEMBL1458912 37856 38 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 247 3 1 3 3.1 Cc1cc(SC(C)C(=O)O)nc2ccccc12 nan
1442575 38096 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1460883 38096 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 6 1 4 3.7 CCCc1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
4412828 38195 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
CHEMBL1461851 38195 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 9 1 7 2.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)COc2ccc(C#N)cc2)c1 nan
1838049 38260 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1462354 38260 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 0.4 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
15945416 39004 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
CHEMBL1468328 39004 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 3.5 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CSc1ncnc2ccccc12 nan
4905842 39023 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
CHEMBL1468444 39023 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 9 4.4 CSc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(SC)s2)cc1 nan
6498441 39133 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
CHEMBL1469364 39133 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 2.7 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NC1CCCC1 nan
4356276 39236 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1470300 39236 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 8 4.1 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
3776625 39291 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
CHEMBL1470725 39291 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Br)c2)no1 nan
3186626 39312 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
CHEMBL1470851 39312 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 9 1.1 CCC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
7256722 39636 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
CHEMBL1474450 39636 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 2.4 Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3F)nc(=O)n2c1 nan
15990395 39784 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
CHEMBL1476510 39784 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1cccc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 nan
1506838 39829 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
CHEMBL1477044 39829 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 4 3.1 Cc1cc(CNC(=O)COc2ccc(C#N)cc2)c2ccccc2n1 nan
1471774 39872 24 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
CHEMBL1477426 39872 24 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 3.0 CSc1cc(-c2ccccc2)nc(O)c1C#N nan
20970002 39882 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
CHEMBL1477514 39882 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1 nan
2931382 40176 14 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1480089 40176 14 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 2 5 2.1 COC(=O)c1sccc1NC(=O)C1CC=CCC1C(=O)O nan
7120051 40183 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1480178 40183 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
16018856 40203 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
CHEMBL1480328 40203 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 0 8 5.5 COc1ccc(-c2nc(CSc3nnc(C)n4c3cc3sccc34)c(C)o2)cc1 nan
3451317 40216 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
CHEMBL1480436 40216 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 7 0.8 CN(C)S(=O)(=O)c1cccc(NC(=O)CSc2nncn2C)c1 nan
3535142 40338 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
CHEMBL1481365 40338 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 9 1 9 3.4 O=C(O)CCCCCn1c(SCc2cc(=O)n3ccccc3n2)nc2ccsc2c1=O nan
3574141 40389 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1481920 40389 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 0 6 2.1 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(C(=O)OCC(=O)N2CCCC2)c1 nan
5736472 40681 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
CHEMBL1484332 40681 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 6 1 7 2.5 O=c1c2ccccc2nc(/C=C/c2ccc([N+](=O)[O-])o2)n1CCCO nan
5304429 40710 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1484671 40710 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 1 4 2.4 CC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 nan
16012070 40746 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
CHEMBL1484919 40746 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 7 2.9 Cc1cc(=O)n2nc(N3CCC(C(=O)Nc4c(C)cccc4C)CC3)sc2n1 nan
4399091 40748 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1484932 40748 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1ccccc1C1C(C(=O)c2ccc(C)o2)=C(O)C(=O)N1c1cc(C)on1 nan
1387364 40803 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1485560 40803 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1576237 40803 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.2 CNS(=O)(=O)c1ccc(OC)c(-c2nnc3c4ccccc4c(C)nn23)c1 nan
6622721 41074 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
CHEMBL1487831 41074 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 5 3.6 CNc1nc2c(-c3ccc(Cl)cc3)nnn2c2ccccc12 nan
1002526 41115 11 None -2 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
CHEMBL1488092 41115 11 None -2 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 4 4.1 O=C(O)c1cc(-c2ccc3c(c2)OCO3)nc2ccc(Br)cc12 nan
7190684 41173 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1488468 41173 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
5881431 41272 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1489225 41272 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 1 7 4.2 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2032322 41387 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
CHEMBL1490215 41387 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 8 1 7 3.5 CCN(CC)CCCNc1nc(SC)nc2sc3c(c12)CCN(C)C3 nan
755499 41494 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
CHEMBL1490891 41494 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 7 1.0 COC(=O)Cn1cnc2c(C#N)c3n(c2c1=O)CCCCC3 nan
1283516 41686 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
CHEMBL1492212 41686 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 7 0.9 O=c1[nH]n2cc(-n3cc([N+](=O)[O-])cn3)cnc2c1Br nan
774862 41754 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
CHEMBL1492732 41754 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 0 4 3.1 Cn1c(-c2ccc([N+](=O)[O-])cc2)nc2ccccc21 nan
3279901 41850 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
CHEMBL1493652 41850 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 4 3.0 CC(=O)NC(CSc1cc(C)nc2ccc(Br)cc12)C(=O)O nan
4795978 41853 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
CHEMBL1493688 41853 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 3.8 CN(C)S(=O)(=O)c1cccc(COc2ncnc3c(Cl)cc(Cl)cc23)c1 nan
15988336 41934 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1494501 41934 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1cccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
664285 41951 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1494683 41951 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 3 0 5 3.1 CC(=O)CSc1ncnc2c1oc1ccccc12 nan
748270 41993 46 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
CHEMBL1495086 41993 46 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 218 0 0 4 2.2 Cc1nnc2c3ccccc3c(Cl)nn12 nan
3186635 42103 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1496152 42103 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 0 9 -0.8 CCN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
2561752 42339 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
CHEMBL1498284 42339 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 3.2 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCS3 nan
21552 42383 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
CHEMBL1498782 42383 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 7 0.1 Cn1c(=O)c2c(nc(Cc3ccc(N)cc3)n2C)n(C)c1=O nan
7677140 42436 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
CHEMBL1499143 42436 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 5 2.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1cccnc1 nan
2816379 42600 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
CHEMBL1500551 42600 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 0 8 2.1 CCOC(=O)c1nnn2c1nc(SCC(C)=O)c1ccccc12 nan
18554434 42637 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
CHEMBL1500823 42637 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 1 8 1.8 O=C(CSc1ncnc2c1nnn2Cc1ccccc1F)NCC1CCCO1 nan
5077853 42721 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
CHEMBL1501692 42721 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 1 8 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1 nan
7120056 42726 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1501734 42726 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1 nan
3884053 42882 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
661074 42882 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
CHEMBL1503060 42882 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 1 5 4.0 CN(C)CCCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1ccccc1 nan
20957430 42919 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
CHEMBL1503367 42919 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 3.2 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(NCc4ccc5c(c4)OCO5)nn23)c1 nan
16452701 43025 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
CHEMBL1504372 43025 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)n1 nan
3457991 43155 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
CHEMBL1505540 43155 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 5 1 8 3.2 Cc1ccc(F)cc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
5198374 43169 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1505625 43169 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 7 2.4 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
986582 43271 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
CHEMBL1506399 43271 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 2 4 3.2 CCc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C)c2c1 nan
1811810 43304 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1506727 43304 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 2 3.5 C=CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
135528107 43828 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
CHEMBL1511291 43828 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 5 3.2 CCN(CC(=O)NC(C)C)Cc1nc(O)c2cc(Br)cc(Br)c2n1 nan
16496658 43946 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
CHEMBL1512634 43946 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.1 CC1CCCN(C(=O)COC(=O)CNC(=O)c2sc3ccccc3c2Cl)C1 nan
15988304 44024 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
CHEMBL1513808 44024 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 0 8 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)N3CCN(c4ccccc4)CC3)nnc12 nan
16026221 44140 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
CHEMBL1515615 44140 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 1.2 CCOC(=O)C1CCN(C(=O)Cn2c(=O)cc(C)c3c(C)nn(C)c32)CC1 nan
662069 44293 9 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
CHEMBL1517409 44293 9 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 1.8 COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 nan
3489758 44351 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
CHEMBL1518029 44351 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 2 9 0.9 Cn1c(=O)c2ncn(CC(=O)N=Nc3c(O)[nH]c4ccccc34)c2n(C)c1=O nan
16018686 44514 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
CHEMBL1519470 44514 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 6 4.3 Cc1cc2c(cc3c(SCC(=O)Nc4ccc(Cl)cc4F)nncn32)o1 nan
20957225 44532 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
CHEMBL1519640 44532 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 9 1.7 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)nc1 nan
2991435 44550 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
CHEMBL1519787 44550 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 6 2.8 COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2ccc(Br)o2)c1 nan
5959865 44665 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
CHEMBL1520789 44665 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 6 4.0 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccc(F)cc3)ccc2O1 nan
4197564 44831 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
CHEMBL1522190 44831 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 11 1 8 3.9 COc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
5064245 44849 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
CHEMBL1522316 44849 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 5 1 5 1.3 O=C(COc1ncnc2ccccc12)NCC1CCCO1 nan
3317909 44852 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
3536112 44852 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
CHEMBL1522365 44852 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(CCN4CCOCC4)C3c3ccc(C(C)(C)C)cc3)oc12 nan
20957467 44927 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
CHEMBL1523099 44927 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 9 1 8 1.8 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4)CC3)n2n1 nan
3242118 44940 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
CHEMBL1523214 44940 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 1 5 2.6 Cc1nn(C(C)C(=O)O)c(=O)c2c1sc1ccccc12 nan
3178468 44998 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1523743 44998 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 8 0.6 CCn1c(SCC(=O)N2CCCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
774385 45221 55 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
CHEMBL1525902 45221 55 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 192 1 1 4 2.3 Cc1ccccc1-c1nnc(S)o1 nan
6156848 45234 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
CHEMBL1525999 45234 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 6 3.9 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3ccccc3)ccc2O1 nan
20923115 45494 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1528270 45494 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 0 6 3.1 CCN(c1ccccc1)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
1173803 45604 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1529195 45604 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 0 9 0.3 CCCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
1150969 45605 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
CHEMBL1529199 45605 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 2 6 3.2 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1 nan
20957502 45672 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
CHEMBL1529803 45672 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1cccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)c1 nan
3146230 45857 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
CHEMBL1531505 45857 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 6 2.7 Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C nan
20888842 46122 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1533752 46122 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 9 1.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
7677714 46124 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
CHEMBL1533761 46124 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 5 3.2 Cc1ccc(C(=O)NCc2nnc3c(C(F)(F)F)cc(Cl)cn23)o1 nan
16018626 46171 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
CHEMBL1534283 46171 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1ccc(NC(=O)CSc2nncn3c2cc2occc23)c(OC)c1 nan
2415319 46173 28 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1534296 46173 28 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 5 4.0 O=C(O)c1ccccc1Sc1ncnc2sc3c(c12)CCC3 nan
15988400 46202 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
CHEMBL1534534 46202 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 7 3.0 CCn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccc(Cl)cc3)nnc12 nan
3559456 46305 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
CHEMBL1535636 46305 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccc(Br)c2)no1 nan
752859 46328 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
CHEMBL1535864 46328 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 6 2.6 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccccc2)n1 nan
1258096 46364 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
CHEMBL1536340 46364 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 7 3.1 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)c(Cl)c1 nan
5911396 46388 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
CHEMBL1536589 46388 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 8 3.5 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)OCCO4)C2c2ccc(F)cc2)s1 nan
2968508 46490 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
CHEMBL1537461 46490 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 3.4 O=C(COc1ccccc1)NC(=S)Nc1cccc2cc(O)ccc12 nan
973903 46650 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
CHEMBL1538711 46650 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 3 7 1.5 O=C(NNc1nc(=O)c2cccnc2s1)c1ccccc1O nan
4786350 46703 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
CHEMBL1539182 46703 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 4 0 6 2.6 COC(=O)c1ccc(COc2ncnc3ccccc23)o1 nan
4199276 46710 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
CHEMBL1539261 46710 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 10 -0.3 Cn1c(=O)c2nc(NNC(=O)c3ccc([N+](=O)[O-])cc3)cnc2n(C)c1=O nan
20957177 46735 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
CHEMBL1539515 46735 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 8 2.4 O=C(CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)NCc1ccccc1Cl nan
775376 47020 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
CHEMBL1541812 47020 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 7 -0.1 Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCC2)n(C)c1=O nan
2027988 47110 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
CHEMBL1542663 47110 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccc(F)cc1 nan
7190638 47281 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
CHEMBL1544038 47281 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 7 2.9 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccccc1 nan
5291252 47338 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1544399 47338 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 4 4.3 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3531704 47398 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
CHEMBL1544885 47398 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 5.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccc(Oc3ccccc3)c2)no1 nan
1254436 47435 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1545144 47435 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 2 1 10 -0.3 Cn1c(=O)c2c(nc(Br)n2Cc2nnc(N)s2)n(C)c1=O nan
20923178 47478 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
CHEMBL1545457 47478 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)o1 nan
2827527 47491 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
CHEMBL1545583 47491 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 0 2 3.2 Cc1ccc2c(ccc(=S)n2C)c1 nan
4114707 47543 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
CHEMBL1546017 47543 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 6 2.6 Cc1cc2nnc(SCC(=O)NCC3CCCO3)n2c2ccccc12 nan
6620293 47621 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
CHEMBL1546743 47621 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 0 5 3.8 O=C(C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1)N1CCCC1 nan
2341870 47631 2 None -3 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
CHEMBL1546820 47631 2 None -3 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 0 5 4.1 Cc1ccc(C)n1-c1ccc(-c2nnc3n2CCCCC3)s1 nan
2150404 47874 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1549101 47874 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 1 1 4 3.8 O=c1c2oc3ccccc3c2[nH]c(=S)n1-c1ccccc1 nan
2482804 47977 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
CHEMBL1549963 47977 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 5 2 8 -0.4 C=CCNC(=O)NC(=O)COC(=O)c1nc2nccc(C)n2n1 nan
7184632 48106 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1550958 48106 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
16030519 48124 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
CHEMBL1551209 48124 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)cc1 nan
1116231 48228 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
CHEMBL1552691 48228 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.4 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(Cl)c2Cl)n(C)c1=O nan
16031533 48238 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
CHEMBL1552858 48238 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 6 4.5 CCc1ccccc1NC(=O)CSc1nnc(-c2ccc(OC)cc2)s1 nan
16033232 48248 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1552980 48248 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.4 Cc1c(C(=O)NCc2cccc(Cl)c2)sc2ncnc(N(C)C3CCCCC3)c12 nan
2136319 48270 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1553213 48270 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
16018758 48329 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
CHEMBL1554096 48329 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 5 4.5 Cc1cc2c(cc3c(SCc4cccc(F)c4)nnc(C)n32)o1 nan
4808155 48507 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1556293 48507 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 7 0.7 Cn1c(=O)c2c(ncn2CCOc2ccc(F)cc2)n(C)c1=O nan
664905 48646 16 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
CHEMBL1557499 48646 16 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 3.4 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 nan
846378 48760 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
CHEMBL1558527 48760 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 5 3.8 CN(C)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
20970070 48896 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
CHEMBL1559703 48896 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 7 2.8 CCOc1ccc(CNS(=O)(=O)c2cc(CN3C(=O)c4cccnc4C3=O)ccc2OC)cc1 nan
749967 49097 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
CHEMBL1561641 49097 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 208 2 1 5 2.0 COc1ccccc1-c1nnc(S)o1 nan
2816163 49268 22 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
CHEMBL1563125 49268 22 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 2 0 7 0.8 CCOC(=O)c1nnn2c3ccccc3c(=O)n(C)c12 nan
754624 49362 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
CHEMBL1563900 49362 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 0 6 3.0 O=c1c2c(-c3ccc([N+](=O)[O-])cc3)csc2nc2n1CCC2 nan
20923125 49503 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
CHEMBL1565225 49503 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccc(C)cc1 nan
5818870 49512 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
CHEMBL1565288 49512 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4cccnc4)C3c3ccccc3F)ccc2O1 nan
702333 49999 16 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1569119 49999 16 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 0 1 3 2.9 Cn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
1072636 50337 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1572163 50337 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 1.0 CCn1c(SCC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)nc2c1c(=O)n(C)c(=O)n2C nan
4912148 50345 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
CHEMBL1572210 50345 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 8 3.6 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2)s1 nan
719137 50366 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
CHEMBL1572461 50366 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 1 1 3 3.4 CCn1c(=S)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 nan
22518619 50571 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
CHEMBL1574369 50571 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 9 1 8 3.8 CC(C)OCCCn1c(SCC(=O)Nc2ccccc2C(F)(F)F)nc2nccnc2c1=O nan
3516975 50660 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
CHEMBL1575467 50660 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2sccc2Br)nc(-n2cccc2)n1 nan
2109682 50686 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1575697 50686 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 11 0.2 Cc1ccc(C)c(-n2nnnc2SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
16189479 50805 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
CHEMBL1576683 50805 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 0 8 -0.2 Cn1c(=O)c(=O)n(C)c2cc(S(=O)(=O)N3CC(=O)N(CCc4ccccc4)C(=O)C3)ccc21 nan
1173783 50840 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
CHEMBL1577034 50840 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCC(=O)Nc1ccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2CC)cc1 nan
2960985 51051 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
5740252 51051 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
9587839 51051 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
CHEMBL1578738 51051 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1cccnc1 nan
3221467 51063 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1578803 51063 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 8 1 6 3.0 CCOC(=O)CNC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6409200 51199 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
CHEMBL1580121 51199 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 2 5 3.4 O=C(O)c1ccccc1CSc1n[nH]c2c3ccccc3nc-2n1 nan
20957463 51215 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
CHEMBL1580225 51215 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 10 2 7 2.5 O=C(CCc1nnc2ccc(NCCCN3CCCC3=O)nn12)NCc1ccccc1Cl nan
929935 51299 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
CHEMBL1580962 51299 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 1 2 6 4.2 CC(C)c1nc2sc3c(O)nc(S)nc3c2c2c1CCCC2 nan
3220371 51307 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1581023 51307 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 6 2.9 CC(C)C(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
2916260 51384 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1581657 51384 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 10 0.1 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
1324776 51480 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
CHEMBL1582422 51480 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 9 2 8 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2cc(OC)nc(OC)n2)cc1 nan
4976300 51653 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
CHEMBL1583844 51653 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 9 4.0 CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(OC)c2)s1 nan
5083492 51792 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
CHEMBL1585012 51792 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 13 1 5 5.1 CC[N+](CC)(CCCCS(=O)(=O)[O-])CCNP1(=O)C=C(c2ccccc2)OC(c2ccccc2)=C1 nan
6624747 52023 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
CHEMBL1586923 52023 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 2.6 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccccc3)nnc12 nan
2384712 52332 23 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
CHEMBL1589567 52332 23 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 3 4.8 Brc1ccc(-c2nc3ccccc3s2)s1 nan
16030403 52407 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
CHEMBL1590296 52407 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 4 4.8 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCC(C)C)cc1 nan
16022890 52458 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
CHEMBL1590948 52458 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 2 6 5.2 COc1cc2cc(CNc3ccccc3)c(=O)n(CC(=O)Nc3cccc(Cl)c3C)c2cc1OC nan
16029271 52544 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
CHEMBL1592100 52544 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 4 0 8 1.5 CCOC(=O)c1noc2ncn(Cc3cccc(C#N)c3)c(=O)c12 nan
3431356 52565 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1592367 52565 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 9 2 4 5.8 CCc1ccc(Nc2cc(C(=O)NCCCN(C)c3ccccc3)c3ccccc3n2)cc1 nan
16331440 52590 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
CHEMBL1592707 52590 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 0 6 1.9 CC(C(=O)OCC(=O)N(C)C1(C#N)CCCCC1)N1C(=O)c2ccccc2C1=O nan
22518595 52721 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
CHEMBL1594419 52721 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.0 COc1ccccc1NC(=O)CSc1nc2nccnc2c(=O)n1Cc1cccs1 nan
3630300 52733 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
CHEMBL1594498 52733 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 5 4.9 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(Cl)cc2)n1 nan
16018788 52854 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
CHEMBL1595485 52854 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 CCc1cccc(C)c1NC(=O)CSc1nnc(CC)n2c1cc1occc12 nan
135454734 52933 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
CHEMBL1596208 52933 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 3 9 1.2 Nc1cc(O)nc(SCC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc2Cl)n1 nan
3151377 52950 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
CHEMBL1596336 52950 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCCC1 nan
2743162 53048 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
CHEMBL1597261 53048 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)cc(Cl)c2)n1 nan
5175738 53094 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
CHEMBL1597711 53094 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 3 2 5 6.0 Nc1c(C(=O)Nc2ccc(F)cc2)sc2nc(-c3cccs3)cc(C(F)(F)F)c12 nan
16018618 53107 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
CHEMBL1597835 53107 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)cc(NC(=O)CSc2nncn3c2cc2occc23)c1 nan
2931308 53211 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
CHEMBL1598795 53211 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 2.4 COC(=O)c1cc(C)sc1NC(=O)C1CC=CCC1C(=O)O nan
16033260 53227 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1598947 53227 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccc(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
7202413 53395 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
CHEMBL1600469 53395 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 8 1.2 Cc1nnc2sc(SCC(=O)N3CCC(C)CC3)nn2c1=O nan
893043 53419 13 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
CHEMBL1600661 53419 13 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 3 2.4 O=c1[nH]c(=S)c2c(n1-c1ccccc1)CCC2 nan
15988297 53581 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
CHEMBL1602305 53581 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.1 Cc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1F nan
20923199 53614 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
CHEMBL1602602 53614 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 7 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N(C)Cc1ccco1 nan
2138501 53618 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
CHEMBL1602628 53618 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 7 1.0 COc1ccc(C=O)cc1Cn1cnc2c(cnn2C)c1=O nan
16301839 53620 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
CHEMBL1602634 53620 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 11 1.2 Cn1c(N)c(C(=O)CSc2nnc(NC3CCCCC3)s2)c(=O)n(C)c1=O nan
2960993 53831 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5740253 53831 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
9587840 53831 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
CHEMBL1604402 53831 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccccn1 nan
5925277 53848 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
CHEMBL1604541 53848 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 8 1.2 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCCOC)CC1 nan
2928283 53896 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
CHEMBL1605019 53896 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCC4)c3nc12 nan
6460757 54483 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
CHEMBL1609708 54483 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 6 2.4 Cc1cc2c(SCC(=O)NCC3CCCO3)ncnc2s1 nan
15991073 54614 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
CHEMBL1610897 54614 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1cccc(C(=O)Nc2ccc3oc(-c4cccc5c(Br)cccc45)nc3c2)c1 nan
7889635 54672 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
CHEMBL1611331 54672 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 7 1.5 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3)cc(=O)n12 nan
778300 54847 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
CHEMBL1612871 54847 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 2 1 10 -1.1 Cn1c(=O)c2c(ncn2Cc2nnc(N)s2)n(C)c1=O nan
705485 55244 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1321656 55244 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
CHEMBL1617945 55244 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 5 3.9 CCOC(=O)c1cnc2ccccc2c1Nc1cccc(C(=O)O)c1 nan
20279 55357 98 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
CHEMBL1619 55357 98 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
1187262 55631 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1462585 55631 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
CHEMBL1621394 55631 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 6 3.7 CN1CCC(N(C)c2nc(-c3ccc([N+](=O)[O-])cc3)nc3ccccc23)CC1 nan
44143728 60247 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1553539 60247 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
CHEMBL1741041 60247 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 2 11 -0.4 CC1(C)O[C@@H]2[C@@H](COS(=O)(=O)O)O[C@@H](n3cnc4c(N)ncnc43)[C@@H]2O1 nan
135641876 72165 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
CHEMBL1979668 72165 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 2 10 -0.7 COc1cc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1O nan
135475570 72658 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
CHEMBL1995496 72658 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 7 2.3 CCN(CC)S(=O)(=O)c1cccc(N/N=C2/C(=O)Oc3ccccc3C2=O)c1 nan
9632269 72921 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
CHEMBL2004582 72921 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2cccnc2)n(C)c1=O nan
9553490 107997 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
CHEMBL3194107 107997 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 9 -0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C/c2ccco2)n(C)c1=O nan
6905987 108339 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
CHEMBL3198000 108339 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.5 Sc1nnc(-c2ccccn2)n1/N=C/c1ccc(-c2ccccc2Br)o1 nan
540540 108420 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
CHEMBL3198706 108420 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 7 1.1 CC(=O)/N=c1\sc2nc3ccccc3nc2n1N(C(C)=O)C(C)=O nan
5339637 108509 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
CHEMBL3199816 108509 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 7 2 5 1.4 O=C(COc1ccccc1)NCC(=O)N/N=C/c1cccs1 nan
9553411 108902 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
CHEMBL3210887 108902 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 8 -0.0 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccccc2)n(C)c1=O nan
9634938 108912 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
CHEMBL3211064 108912 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 9 -0.6 Cn1c(=O)c2c(ncn2CCC(=O)N/N=C/c2ccncc2)n(C)c1=O nan
1116825 184263 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
CHEMBL483773 184263 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 2.4 Cc1ccnc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
7190719 200946 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL601822 200946 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1ccc(CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
3259 23360 55 None - 1 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
CHEMBL1332616 23360 55 None - 1 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 836 0 2 5 6.1 O=C1OC2(c3ccccc31)c1cc(I)c(O)c(I)c1Oc1c2cc(I)c(O)c1I nan
3228920 29738 5 None -31 2 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
CHEMBL1386739 29738 5 None -31 2 Human 3.8 pPotency = 3.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 2 5 5.9 O=C(CSc1nc(-c2ccccc2F)nc2nc[nH]c12)Nc1c(Cl)cc(Cl)cc1Cl nan
2099 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
4740 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
7095 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
CHEMBL628 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
DB00806 3046 81 None -234 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1c(=O)c2n(C)cnc2n(c1=O)C nan
3220395 19627 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1300380 19627 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 6 2.7 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
16452711 19749 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
CHEMBL1301248 19749 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 8 2.9 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccccc4)ccc3=O)cc2)c1C nan
4134237 20027 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
CHEMBL1303471 20027 9 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 4 3.0 CC1CCCN(C(=O)CSc2cnc3ccccc3n2)C1 nan
2816749 20236 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
CHEMBL1305245 20236 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 0 6 1.5 CCOC(=O)N1CCc2c(sc3ncn(C)c(=O)c23)C1 nan
225068 20339 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
CHEMBL1306052 20339 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 2 6 0.5 CC(=O)Nc1ccc(Cc2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)cc1 nan
2377168 20677 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
CHEMBL1308771 20677 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 6 1.7 NS(=O)(=O)c1ccc(CCNC(=O)CSc2ncnc3ccccc23)cc1 nan
6311448 20896 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
CHEMBL1310631 20896 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 2 6 2.6 CNc1ccc(/C=C(\C#N)C(=O)Nc2ccccn2)cc1[N+](=O)[O-] nan
4454085 21102 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1312229 21102 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 8 1.1 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
3269960 21164 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
CHEMBL1312645 21164 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 9 3.7 O=C(O)CCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
5811072 21197 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
CHEMBL1312900 21197 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 7 3.8 O=C(C1=C(O)C(=O)N(c2nccs2)C1c1ccccc1F)c1ccc2c(c1)OCCO2 nan
3719872 21278 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
CHEMBL1313510 21278 16 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 3.8 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)no1 nan
7151338 21357 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
CHEMBL1314161 21357 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 2.8 CCS(=O)(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 nan
16010497 21399 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
CHEMBL1314605 21399 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.0 COc1ccc(CCNC(=O)c2cnc3ccc(C)cn3c2=O)cc1OC nan
4119285 21481 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
CHEMBL1315733 21481 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
16020283 21519 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
CHEMBL1316147 21519 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 5 4.1 CCOc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3s2)cc1 nan
2645859 21552 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
CHEMBL1316688 21552 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 6 2.6 Cc1cnc(C(=O)OCC(=O)c2ccc(Br)s2)cn1 nan
16019079 21626 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1317634 21626 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.2 CCc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
16025698 21654 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
CHEMBL1317991 21654 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 6.1 CC(NC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1)c1ccccc1 nan
16018836 21711 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
CHEMBL1318579 21711 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 1 6 4.6 O=C(CSc1nncn2c1cc1sccc12)Nc1ccc(Br)cc1F nan
658390 22134 23 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
CHEMBL132222 22134 23 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 4 2.7 CSc1sc(C(=O)O)c2c1C(=O)CCC2 nan
4302597 22368 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
CHEMBL1324305 22368 13 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 6 3.1 Cc1c(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)nn1C nan
16825458 22623 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
CHEMBL1326698 22623 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1OC nan
961104 22930 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
CHEMBL1329229 22930 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 5 2 5 1.8 CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1OC nan
753118 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1331202 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
CHEMBL1532594 23179 57 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 1 3 4.7 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)s1 nan
5302178 23653 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
CHEMBL1334923 23653 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
4213677 23754 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1335629 23754 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 5 2 9 2.3 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc5c(c4)OCO5)c(=N)n(CC4CCCO4)c3nc12 nan
2410320 23989 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
CHEMBL1337652 23989 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 6 2.5 Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
6624813 24307 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
CHEMBL1340556 24307 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 7 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCCCC3)nnc12 nan
16189291 24459 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1341871 24459 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 0 8 2.6 CCOC(=O)C(CC)Sc1ccc2nnc(-c3cccnc3)n2n1 nan
2835302 24645 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
CHEMBL1343308 24645 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 1 2 4 3.4 CCC1(C)Cc2ccccc2-c2nc(S)nc(O)c21 nan
9115295 24679 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
CHEMBL1343609 24679 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 3 1 4 4.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1C(F)(F)F nan
874496 24739 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
CHEMBL1344171 24739 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 4 2 2 4.0 CC(C)C(=O)Nc1ccc(Nc2ccccc2)cc1 nan
5040775 24759 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
CHEMBL1344340 24759 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 5 1.5 CC1CCCCC1NC(=O)Cn1nnc2ccccc2c1=O nan
7190697 24828 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1344913 24828 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 9 1.0 CCOC(=O)CNC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
1279973 24873 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
CHEMBL1345308 24873 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 10 0.8 COCc1cc(C)nc(Sc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1C#N nan
16187878 24953 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
CHEMBL1346041 24953 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 8 3.6 CCOC(=O)CC(NC(=O)CCc1c(C)nc2nc(C)nn2c1C)c1ccc(OC(C)C)cc1 nan
4911180 24955 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1346060 24955 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 8 4.3 C=CCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
6626039 25037 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
CHEMBL1346717 25037 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 7 1 8 2.2 CCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3cccnc3)nnc12 nan
4884017 25060 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
CHEMBL1346905 25060 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 0 6 2.9 CCN1c2ccc(S(=O)(=O)N3CCOCC3)cc2N(Cc2ccc(OC)cc2)C1C nan
5916900 25354 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1349404 25354 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2421577 25447 5 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
CHEMBL1350197 25447 5 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 0 5 3.2 COC(=O)CCc1c(C)c(C(=O)c2ccco2)c2ccccn12 nan
2429966 25503 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
CHEMBL1350669 25503 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 0 7 2.8 COc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1OC nan
5921143 25692 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
CHEMBL1352285 25692 17 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 10 1.5 CCCN1C(=O)/C(=C/c2c(N3CCNC(=O)C3CC(=O)OC)nc3c(C)cccn3c2=O)SC1=S nan
2926991 25723 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
CHEMBL1352465 25723 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 4.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)n1 nan
16015204 25988 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
CHEMBL1354415 25988 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 7 4.5 COC(=O)c1c(-c2cccs2)csc1NC(=O)c1ccc(OC)c(OC)c1 nan
16030461 26040 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1355113 26040 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 4 4.2 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
23602530 26122 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
CHEMBL1356159 26122 0 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 5 2.2 Cc1ccc(Cn2c(CCC(=O)O)nc3ncccc3c2=O)cc1 nan
16018072 26175 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1356862 26175 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 7 1 4 3.8 Cc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
1077055 26217 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1357427 26217 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 8 0.3 CC(=O)c1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
16021425 26230 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
CHEMBL1357639 26230 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 4 6.3 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(Cl)c4)cc(C)c3c2)c1 nan
16030521 26244 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
CHEMBL1357883 26244 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 4.6 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2)c1 nan
16030369 26269 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
CHEMBL1358199 26269 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 4.9 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(C)cc2)c1 nan
15987639 26295 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
CHEMBL1358546 26295 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 4 5.5 Cc1ccc(NC(=O)CSc2nc3ccccc3nc2Cc2ccccc2F)cc1F nan
881482 26824 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
CHEMBL1363117 26824 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 3 3.7 O=S(=O)(Nc1ccccn1)c1ccc(Cl)c2ccccc12 nan
3193431 26871 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
CHEMBL1363552 26871 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 7 0 8 4.3 COc1ccc(Cn2nnnc2C(c2ccc3ncccc3c2)N2CCN(C3CCCCC3)CC2)cc1 nan
1261960 26875 9 None -7 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
CHEMBL1363571 26875 9 None -7 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 5 3.5 NS(=O)(=O)c1ccc(CNC(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)cc1 nan
7190718 26987 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1364582 26987 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 0 6 3.6 Fc1cccc(CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
20884309 26994 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
CHEMBL1364643 26994 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 8 1.1 CCc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
4152428 27029 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1364957 27029 7 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 5.0 CCOc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
5109926 27063 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
CHEMBL1365247 27063 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 2 8 2.6 COc1ccc(CCn2c(=N)c(C(=O)NCC3CCCO3)cc3c(=O)n4cccc(C)c4nc32)cc1 nan
2959558 27066 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
CHEMBL1365264 27066 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 3.3 CCOC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2Br)CC1 nan
15988059 27122 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
CHEMBL1365674 27122 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 1 10 2.6 COC(=O)c1cccc(Nc2nn3c(=O)c4cc5c(cc4nc3s2)OCO5)c1 nan
16015914 27128 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
CHEMBL1365703 27128 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 2 0 4 6.1 Cc1c(C(=O)N2CCC(c3nc4ccccc4s3)CC2)oc2cc(Br)ccc12 nan
912209 27141 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
CHEMBL1365893 27141 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 3 5 1.9 NC(S)=Nc1cccc(-c2nnc(S)o2)c1 nan
3719648 27717 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
CHEMBL1370349 27717 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 4.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc3ccccc23)s1 nan
1775727 27996 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
CHEMBL1372393 27996 16 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 0 5 4.3 COc1ccccc1CN1COc2ccc3c(oc(=O)c4ccccc43)c2C1 nan
16193912 28438 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
CHEMBL1375345 28438 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 10 1 6 4.8 CCCCN(CC)CCCNC(=O)C1CCN(c2ncnc3c2sc2cccc(F)c23)CC1 nan
2818996 28584 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
CHEMBL1376612 28584 5 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.9 COc1ccc(-c2c(C#N)c(N)nc(Sc3ccc(Cl)cc3)c2C#N)cc1 nan
20876288 29192 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
CHEMBL1382060 29192 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 7 1 5 3.5 Cc1ccc(CN2CCSc3ccc(C(=O)NCCCN4CCN(C)CC4)cc32)cc1 nan
4902824 29264 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1382669 29264 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
408543 29617 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
CHEMBL1385852 29617 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 3 1 3 2.4 O=C(O)CSc1ccc2ccccc2n1 nan
16452903 29642 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
CHEMBL1386060 29642 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 8 2.7 Cc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(S(=O)(=O)Nc4nccc(C)n4)cc3)n2)cc1 nan
5866058 29667 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
CHEMBL1386260 29667 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)c1 nan
2219052 30144 10 None -3 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
CHEMBL1389959 30144 10 None -3 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 6 4.2 CCCCn1nnc(NC(=O)c2sc3cc(Cl)ccc3c2Cl)n1 nan
974402 30272 14 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
CHEMBL1391097 30272 14 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 2 2 3.4 CC(C)NC(=S)NC(=O)c1ccc(-c2ccccc2)cc1 nan
4385170 30416 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1392345 30416 12 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 4 4.9 CCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
2492440 30449 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1392606 30449 26 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 3.4 Cc1ccccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
7207181 30497 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
CHEMBL1393087 30497 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 7 2.9 O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccc2c(c1)OCO2 nan
16025764 30709 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
CHEMBL1395096 30709 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 0 3 4.6 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCCCC2)s1 nan
5839687 30852 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
CHEMBL1397071 30852 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 1.7 COCCNC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O nan
5789902 30914 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1397920 30914 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 5 4.0 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(F)cc2)cc1 nan
3288231 30935 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
CHEMBL1398189 30935 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 4 5.7 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
15991174 30965 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
CHEMBL1398548 30965 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 3 3 7 1.6 Cc1cc(Nc2ccc(C(=O)O)c(O)c2)n2ncnc2n1 nan
16025760 31097 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1399794 31097 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
135444909 31157 10 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
CHEMBL1400344 31157 10 None -4 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 8 3 10 3.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)cc2)n1 nan
16023027 31184 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1400601 31184 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
2005962 31190 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
CHEMBL1400661 31190 8 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 7 3.5 CC(C)OCCCN1CN(S(=O)(=O)c2cccs2)c2nc3ccccc3nc21 nan
4176332 31227 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
CHEMBL1401042 31227 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 3 1 5 3.6 CN1CCN(NC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)CC1 nan
7693269 31267 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
CHEMBL1401345 31267 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 1 1 4.1 O=C(c1cc2cc(Br)ccc2[nH]1)N1CCc2ccccc21 nan
1842681 32616 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1412841 32616 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 0 8 1.2 CCOC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
3159273 32804 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
CHEMBL1414335 32804 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 5 3.0 Cc1c2c(n3c(nc4ccccc43)c1C#N)N(CCCN(C)C)CC2 nan
773430 32920 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
CHEMBL1415344 32920 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 O=C(O)c1ccc2nc3c(nc2c1)-c1ccccc1C3=O nan
1172271 33217 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1417950 33217 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 0 9 0.1 CCCn1c(SCC(=O)N2CCN(CC)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
20957513 33386 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1419386 33386 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 12 2 8 2.6 CSc1ccc(CCNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
656126 34338 5 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
CHEMBL1427319 34338 5 None -1 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 4.1 CCOC(=O)c1c(NC(=O)CSc2nc(C)cc(C)c2C#N)sc(C(C)=O)c1C nan
24792443 34414 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
CHEMBL1428040 34414 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 5 3.1 CCc1nc(SCC(=O)NNC(=O)c2ccc(C)cc2)c2ccccc2n1 nan
5295519 35115 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
CHEMBL1434105 35115 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 10 0.1 COC(=O)c1cc(OC)c(OC)c(OC)c1NC(=O)c1cc(=O)n(C)c(=O)n1C nan
16959503 35199 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
CHEMBL1435220 35199 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 9 2.5 CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
2448286 35222 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
CHEMBL1435449 35222 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 11 1.6 Cn1c(N)c(C(=O)CSc2nn(-c3ccccc3)c(=S)s2)c(=O)n(C)c1=O nan
16018790 35347 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
CHEMBL1437127 35347 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.6 CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2F)c2cc3occc3n12 nan
135401612 35609 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
CHEMBL1439558 35609 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 3 7 1.5 Nc1cc(O)nc(SCC(=O)Nc2cccnc2Cl)n1 nan
15990899 35719 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
CHEMBL1440596 35719 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 9 1 10 5.2 COc1cc2nc(SCC(=O)Nc3cccc(C)c3)n3nc(CCn4c(C)nc5ccccc54)nc3c2cc1OC nan
16034663 35744 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
CHEMBL1440811 35744 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 7 2.3 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3)nnc12 nan
5898351 35915 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
CHEMBL1442346 35915 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 6 4.2 Cc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
986518 35974 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
CHEMBL1442810 35974 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 4 3.3 Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccc(Cl)cc12 nan
16009462 35983 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1442959 35983 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.6 CC(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
7245567 36007 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1443187 36007 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 1.9 COc1ccc(CNC(=O)CCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4920871 36396 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
CHEMBL1446831 36396 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 7 1.9 O=C(Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3)NCC1CCCO1 nan
139030 36419 33 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
CHEMBL1446983 36419 33 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 196 0 1 2 2.9 O=C1C=C(O)c2cccc3cccc1c23 nan
771978 36430 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
CHEMBL1447058 36430 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 234 3 1 6 1.2 O=C(Nc1ncccn1)c1ccc([N+](=O)[O-])o1 nan
1511203 36508 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
CHEMBL1447724 36508 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 2 7 2.6 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NC(C)(C)CO nan
5310565 36908 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
CHEMBL1450965 36908 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 8 1.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCOCC1 nan
16457956 37025 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
CHEMBL1451892 37025 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 4 8 1.1 CCN(CC)S(=O)(=O)c1cccc(C(=O)NNC(=O)c2ccc3nc(O)c(O)nc3c2)c1 nan
2173828 37617 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
CHEMBL1456908 37617 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 0 3 5.6 CCN(CC)c1nc(-c2ccccc2Cl)c2cc(Br)ccc2n1 nan
20904573 37924 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
CHEMBL1459467 37924 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 1 8 2.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCN(Cc4ccccc4)CC3)nnc12 nan
734076 37953 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
CHEMBL1459745 37953 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 4 1 4 2.4 CCCC(=O)Nc1nc(C)c(C(C)=O)s1 nan
1511643 37954 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
CHEMBL1459750 37954 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 8 1.3 Cc1cc([N+](=O)[O-])nn1CC(=O)Nc1cccc2nonc12 nan
1838806 38084 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
CHEMBL1460751 38084 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 7 3.6 CCOc1cccc(Nc2cc3n(c(=O)n2)CCc2cc(OC)c(OC)cc2-3)c1 nan
16188836 38309 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
CHEMBL1462764 38309 3 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 0 4 4.0 CC1=NOC(=O)/C1=C\c1ccc(-c2ccccc2Br)o1 nan
3332154 38649 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
CHEMBL1465412 38649 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 8 3.2 Cc1nc(N)sc1N=Nc1c(C)n(C)n(-c2ccccc2)c1=O nan
20957223 38756 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1466244 38756 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 8 2.0 Cc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
2350819 38762 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
CHEMBL1466307 38762 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.3 Cc1cc(Br)ccc1SCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
7190691 39103 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1469069 39103 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 8 3.1 CC(=O)c1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
1179824 39283 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
CHEMBL1470707 39283 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 2 7 3.6 CCOC(=O)c1sc2ncnc(Nc3cccc(C(=O)O)c3)c2c1C nan
7207497 39298 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
CHEMBL1470773 39298 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 5 4.2 Cc1c(Cl)cccc1NC(=O)CSc1ccc(-c2cccnc2)nn1 nan
16012892 39512 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
CHEMBL1472696 39512 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 7 2.9 CCNC(=O)c1c(NC(=O)c2nc(S(=O)(=O)CC)ncc2Cl)sc2c1CCCC2 nan
16030433 39655 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
CHEMBL1474670 39655 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 1 6 5.0 COc1cccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)c1OC nan
4547893 39831 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
CHEMBL1477066 39831 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 6 3.3 COc1ccccc1C(=O)Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1 nan
1313916 40096 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
CHEMBL1479446 40096 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 2 5.5 O=C(Nc1cccc(C(F)(F)F)c1)c1ccccc1NC(=O)C1CCCCC1 nan
16021977 40464 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
CHEMBL1482573 40464 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 6 4.5 CCOC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2-n2cccc2)cc1 nan
16025700 40683 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
CHEMBL1484349 40683 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1cccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
4969640 40714 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
CHEMBL1484709 40714 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 1.5 COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1nncs1 nan
2267309 41219 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
CHEMBL1488814 41219 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.8 Cc1cc(N)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
3157588 41489 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
CHEMBL1490855 41489 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 3.7 CC(=O)C1=C(O)C(=O)N(CCc2c[nH]c3ccccc23)C1c1ccccc1 nan
3755909 42074 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
CHEMBL1495948 42074 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 2 0 4 4.1 Cc1cc(-c2ccc(Br)s2)nc(-n2cccc2)n1 nan
6501461 42693 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
CHEMBL1501425 42693 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 9 2.7 CCC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nnc(C)s1 nan
20968950 42743 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
CHEMBL1501847 42743 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 0.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCC(C(N)=O)CC1)C(=O)CO2 nan
7692847 42884 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
CHEMBL1503072 42884 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 6 3.1 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc2c(c1)OCO2 nan
1243282 43002 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
CHEMBL1504174 43002 14 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 2 1 5 4.6 Fc1ccc(-n2c(S)nnc2-c2ccc3ccccc3n2)cc1Cl nan
20888797 43223 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1506053 43223 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 9 1.5 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCN(CCO)CC2)s1 nan
3965652 43245 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
CHEMBL1506226 43245 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 5 3.6 Oc1nc(S)ncc1Oc1ccc(Cl)cc1Cl nan
664243 43484 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
CHEMBL1508235 43484 11 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.7 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cccs2)no1 nan
1564171 43566 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
CHEMBL1509018 43566 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 8 3.9 C=CCn1c(SCC(=O)Nc2sccc2C#N)nc2sc(C)c(C)c2c1=O nan
660816 43730 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
CHEMBL1510509 43730 54 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 5 3.2 COc1ccccc1-c1nnc(S)n1-c1ccccc1 nan
4736989 43889 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1511802 43889 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 7 1.4 O=C(O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
16407031 43907 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1512174 43907 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 9 1 9 3.2 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCCN4CCOCC4)cc3c3ccnc2c31 nan
16021393 43914 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
CHEMBL1512269 43914 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 6 2 4 6.6 Cc1cccc(OCC(=O)Nc2ccc3nc(Nc4cccc(C(F)(F)F)c4)cc(C)c3c2)c1 nan
16018932 44059 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
CHEMBL1514500 44059 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 0 7 6.7 CCc1nnc(SCc2nc(-c3cccc(Cl)c3)oc2C)c2cc3sc(C)cc3n12 nan
20885685 44126 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
CHEMBL1515364 44126 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccccc1CNC(=O)CCCn1nc(C)n2ccnc2c1=O nan
16018754 44153 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
CHEMBL1515810 44153 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 8 3.8 COc1cc(NC(=O)CSc2nnc(C)n3c2cc2oc(C)cc23)cc(OC)c1 nan
4350514 45211 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
CHEMBL1525803 45211 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 1.9 Cc1nc2ccccc2c(=O)n1NC(=O)Cc1ccc([N+](=O)[O-])cc1 nan
135455188 45521 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
CHEMBL1528492 45521 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 9 3.3 N#Cc1c(O)nc(SCC(=O)Nc2nnc(C(F)(F)F)s2)nc1-c1ccccc1 nan
3535143 45685 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
CHEMBL1529863 45685 4 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 9 3.6 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4ccccc4n3)nc3ccsc3c2=O)CC1 nan
16030435 45708 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
CHEMBL1530187 45708 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 4 5.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccccc2Cl)cc1 nan
54677747 45975 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
CHEMBL1532491 45975 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 1 2 7 4.6 O=c1oc2ccccc2c(O)c1[C@H]1c2ccc(O)cc2Oc2c1c(=O)oc1ccccc21 nan
6498569 46009 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
CHEMBL1532759 46009 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 7 2 5 1.0 Cc1ccc(OCC(=O)NCCNC(=O)c2cnccn2)cc1C nan
6060971 46013 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
CHEMBL1532782 46013 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 8 1 6 3.4 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(CCN3CCOCC3)C2c2ccccc2)cc1 nan
3262927 46334 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
CHEMBL1535967 46334 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 1.3 O=C(OCN1C(=O)c2ccccc2C1=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F nan
6018171 46336 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
CHEMBL1535987 46336 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 6 3.9 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1 nan
7120055 46398 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
CHEMBL1536665 46398 10 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 4.4 Cc1ccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)cc1C nan
2086676 46468 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
CHEMBL1537193 46468 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 8 1.3 Cn1c(=O)c(C(=O)COc2ccc(C#N)cc2)c(N)n(Cc2ccccc2)c1=O nan
20888841 46500 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
CHEMBL1537517 46500 12 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 0 8 2.6 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CC)CC2)s1 nan
22334156 46719 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
CHEMBL1539318 46719 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 6 1 9 1.5 COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1OC nan
3151316 46722 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1539382 46722 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CC4CCCO4)c3nc12 nan
17581317 46940 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
CHEMBL1541200 46940 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 1 5 3.7 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccc(Br)o1 nan
6228228 47054 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
CHEMBL1542130 47054 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 7 4.0 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2)s1 nan
2359872 47083 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
CHEMBL1542457 47083 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 4 1 4 2.8 O=C(CSc1cnc2ccccc2n1)NC1CCCC1 nan
2346972 47102 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1542615 47102 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 10 -1.0 CN(C)S(=O)(=O)c1cccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
135420430 47107 11 None -4 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
CHEMBL1542646 47107 11 None -4 3 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 8 3.5 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1cc(C)on1 nan
1866349 47443 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
661670 47443 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1406059 47443 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
CHEMBL1545185 47443 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 4 1 3 2.8 O=C(O)CCSc1ccc2ccccc2n1 nan
4876432 47468 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
CHEMBL1545378 47468 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 2 6 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2cc(O)nc3ccccc23)c1 nan
2595072 47469 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
CHEMBL1545386 47469 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 6 1 4 3.1 O=C(CSc1ncnc2ccccc12)NCCc1ccccc1 nan
2115012 47536 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
CHEMBL1545973 47536 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 10 0.2 CCCn1c(N)c(C(=O)COC(=O)c2c(C)noc2C)c(=O)n(C)c1=O nan
241512 47839 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
CHEMBL1548782 47839 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 1 2 2 3.2 c1ccc(-c2ccc3c(c2)NCCN3)cc1 nan
16189384 48058 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
CHEMBL1550614 48058 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 573 10 2 9 1.4 CSCCC(NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C)C(=O)NC1CCN(Cc2ccccc2)CC1 nan
16019521 48130 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
CHEMBL1551283 48130 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 9 2.5 Cc1ccc(C)c(S(=O)(=O)c2nnn3c2nc(N2CCN(C)CC2)c2sccc23)c1 nan
6414933 48162 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
CHEMBL1551836 48162 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 4.2 CCOC(=O)c1ccc(NC(=O)C(CC)Sc2nnc3c4ccccc4n(C)c3n2)cc1 nan
16018808 48174 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
CHEMBL1551969 48174 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 8 1 7 2.7 CCc1nnc(SC(CC)C(=O)NCCOC)c2cc3occc3n12 nan
5301786 48198 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
CHEMBL1552221 48198 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 1 8 1.0 Cc1ccc(-c2c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc3n2CCO)cc1 nan
1622536 48261 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
CHEMBL1553105 48261 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 4.7 CCCCOC(=O)c1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 nan
16020969 48297 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
CHEMBL1553552 48297 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 5.0 Cc1oc(-c2cccc(Br)c2)nc1CSc1nc2cccnc2[nH]1 nan
4291583 48332 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
CHEMBL1554139 48332 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 14 4 8 2.2 CSCCC(NS(=O)(=O)c1ccc2c(c1)Cc1cc(S(=O)(=O)NC(CCSC)C(=O)O)ccc1-2)C(=O)O nan
20877874 48371 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1554696 48371 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 0 4 3.5 CCCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
16011310 48438 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
CHEMBL1555647 48438 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 0 5 5.5 CCc1nnc(SCc2cccc(Cl)c2)c2cc3sccc3n12 nan
16030467 48966 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
CHEMBL1560326 48966 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 4 5.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)NCc1ccccc1Cl nan
2415608 49018 25 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
CHEMBL1560923 49018 25 None -5 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 2 7 2.8 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3cc4c(cc3nc2Cl)OCCO4)cc1 nan
15988392 49244 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
CHEMBL1562908 49244 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 1 7 2.8 CCn1c(=O)c2sccc2n2c(CCC(=O)Nc3ccc(F)cc3)nnc12 nan
3805026 49357 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
CHEMBL1563863 49357 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 6 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Cl)cc2)no1 nan
6228410 49420 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
CHEMBL1564525 49420 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 4 1 7 4.1 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc4c(c3)CC(C)O4)C2c2ccccc2F)s1 nan
4802105 49589 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
CHEMBL1565823 49589 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 2.8 Cn1cnnc1SCC(=O)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl nan
225436 49836 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
CHEMBL1567800 49836 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 198 0 1 3 1.2 O=C1c2ccccc2C(=O)c2[nH]cnc21 nan
2054020 49946 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
CHEMBL1568611 49946 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 7 4.7 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nc2ccccc2s1 nan
2883018 50109 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
CHEMBL1570092 50109 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 0 1 5 1.6 N#Cc1c2n(c3c(N)ncnc13)CCCCC2 nan
16018256 50243 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
CHEMBL1571269 50243 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 CCOc1ccc(CCNC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)cc1OCC nan
25163648 50377 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
CHEMBL1572593 50377 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 4 4.3 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1c(F)cccc1Cl nan
20957176 50455 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
CHEMBL1573164 50455 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 0 9 0.2 CN1CCN(C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)CC1 nan
4200979 50781 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1576536 50781 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 7 1.0 COC(=O)CCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1132498 50993 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
CHEMBL1578314 50993 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 5 5.1 Cc1ccc2nsnc2c1NC(=O)c1sc2ccccc2c1Cl nan
3220367 51249 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
CHEMBL1580567 51249 3 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 1 6 2.4 COCCNC(=O)C(OC(=O)c1nsc(Cl)c1Cl)C(C)C nan
4343313 51449 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
CHEMBL1582134 51449 15 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.2 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccccc2)n1 nan
3338549 51465 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1582307 51465 14 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 5.3 CCCOc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
20917770 51621 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
CHEMBL1583626 51621 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 7 2.4 CN(Cc1ccco1)S(=O)(=O)c1ccc(CN2C(=O)c3cccnc3C2=O)s1 nan
18562929 51770 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
CHEMBL1584882 51770 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 9 1.1 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCOCC4)nn23)cc1 nan
2427540 52193 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1588321 52193 5 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 10 1.4 Cn1c(N)c(C(=O)CSc2nc3ccccc3c(=O)n2Cc2ccccc2)c(=O)n(C)c1=O nan
20923114 52218 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1588547 52218 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 9 0 6 2.7 CCCN(CCC)S(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
20885679 52422 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
CHEMBL1590561 52422 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 1.9 Cc1nn(CCCC(=O)NCc2ccccc2Cl)c(=O)c2nccn12 nan
16023172 52446 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
CHEMBL1590852 52446 1 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 3.4 CCCCNC(=O)CSc1nnc(C)c2c(C)n(-c3ccccc3)nc12 nan
16016417 52487 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
CHEMBL1591358 52487 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 3.4 Cc1cc(O)c(CN2CCN(c3ccccc3)CC2)c2oc(=O)cc(C)c12 nan
16009611 52645 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
CHEMBL1593455 52645 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1cccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c1)c1ccc(F)cc1 nan
16453157 53103 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
CHEMBL1597782 53103 13 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 8 2.7 O=C(Nc1ccc(S(=O)(=O)Nc2nccs2)cc1)c1nn(-c2ccccc2)ccc1=O nan
15990388 53310 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
CHEMBL1599627 53310 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.4 Cc1c(NC(=O)c2nc3ccccc3n(C)c2=O)cccc1[N+](=O)[O-] nan
20917744 53389 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
CHEMBL1600418 53389 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 1 7 2.3 Cc1ccc(CNS(=O)(=O)c2ccc(CN3C(=O)c4cccnc4C3=O)s2)o1 nan
3252667 53405 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1600566 53405 18 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 4.8 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
5389427 53485 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
CHEMBL1601252 53485 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 1 7 4.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3cc(C)on3)C2c2ccccc2OC)cc1 nan
723168 53811 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
CHEMBL1604196 53811 42 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 4 1 4 4.2 O=C(O)Cc1sc(-c2ccccc2)nc1-c1cccs1 nan
2235547 53950 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
CHEMBL1605444 53950 32 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 3 1 5 2.4 CCOc1ccccc1-c1nnc(S)o1 nan
2927721 54100 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1606632 54100 19 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 2 7 2.6 CCOCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
3417563 54190 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3983329 54190 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1607267 54190 17 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 1 7 3.4 COc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3146573 54415 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1609156 54415 20 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 7 3.5 Cc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
1941998 54448 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
CHEMBL1609358 54448 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4F)sc3n2)c1 nan
5389862 54580 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1610515 54580 6 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 9 1 6 3.5 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
9550945 54743 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1611989 54743 6 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 2 0 5 3.2 CCOC(=O)N1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
2120111 55703 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1484562 55703 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
CHEMBL1622008 55703 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 3 4.3 COc1ccc(Br)cc1-c1nc(CCl)cs1 nan
1724830 55849 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1520781 55849 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
CHEMBL1623209 55849 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 2 8 1.8 NN1C(=O)/C(=C2/Sc3ccccc3N2CCCS(=O)(=O)O)SC1=S nan
9619025 71969 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
CHEMBL1973418 71969 8 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 10 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1OC nan
5065598 72586 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1992834 72586 11 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 0 8 2.9 CCOC(=O)Cn1/c(=N/C(=O)c2cccs2)sc2cc(C(=O)OC)ccc21 nan
5286961 72837 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
9915251 72837 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
CHEMBL2001904 72837 9 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 3 2 4 5.3 CC1=C/C(=C(\c2cc(C)c(O)c(Br)c2)c2ccccc2S(=O)(=O)O)C=C(Br)C1=O nan
95028 93808 31 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
CHEMBL24759 93808 31 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 2 0 6 0.5 Cn1c(=O)c2c(ncn2Cc2ccccc2)n(C)c1=O nan
135723776 107584 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
CHEMBL3189383 107584 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 2 5 2.6 Cc1cc(O)nc(N/N=C/c2c(F)c(F)c(F)c(F)c2F)n1 nan
5342833 107594 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
CHEMBL3189560 107594 10 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 3 9 -2.3 Cn1c(=O)c2nc(N/N=C(/C#N)C(N)=O)[nH]c2n(C)c1=O nan
4564145 107847 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
CHEMBL3192424 107847 11 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(Br)cc2)n(C)c1C nan
135526880 108267 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
135643494 108267 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
137199718 108267 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
CHEMBL3197292 108267 5 None 1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 2 6 3.0 O=C1CC(C(=O)Nc2ccc(Br)cc2)SC(N/N=C/c2ccco2)=N1 nan
9660607 108293 5 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
CHEMBL3197507 108293 5 None -2 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 3 3.8 Cc1ccc(N2C(=O)CS/C2=N\C(=S)Nc2ccccc2)cc1 nan
9583775 108894 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
CHEMBL3210811 108894 2 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 2 7 2.1 Nc1c(C(=O)N/N=C/c2ccc([N+](=O)[O-])cc2)cnn1-c1ccccc1 nan
3669734 198721 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
CHEMBL582737 198721 7 None - 1 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 2.6 CCOC(=O)N1CCN(C(=O)CCCCn2c(=S)[nH]c3ccsc3c2=O)CC1 nan
3324 206438 115 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
CHEMBL880 206438 115 None -1 2 Human 4.8 pPotency = 4.8 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 7 1 9 0.5 CC(=O)OCC(CCn1cnc2cnc(N)nc21)COC(C)=O nan
1028 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
139148732 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
479 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
5816 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
CHEMBL679 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
DB00668 291 71 None -1096 19 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 3 4 4 0.4 CNC[C@@H](c1ccc(c(c1)O)O)O nan
3289443 7065 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1084955 7065 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 5 5.0 Nc1c(C(=O)Nc2cccc(F)c2)sc2nc(-c3cccs3)ccc12 nan
4112670 10480 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
CHEMBL1165197 10480 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 3 4 5.5 O=C(NCCc1ccc(Cl)cc1)C1CCC(CNc2nc(=S)[nH]c3ccccc23)CC1 nan
1003890 18361 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
CHEMBL1271075 18361 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)c1 nan
790786 19769 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
CHEMBL1301385 19769 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 1 4.5 CCc1c(C)nc2ccc(Br)cc2c1Cl nan
6621843 19858 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
CHEMBL1302226 19858 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 1 5 2.4 CCCNc1nc2ccccc2n2c(C)nnc12 nan
926200 20082 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
CHEMBL1303908 20082 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 4 4.0 Fc1cnc(N2CCc3ccccc32)nc1N1CCc2ccccc21 nan
20881176 20370 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1306246 20370 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 1 7 2.3 CC(C)CCn1c(=O)c2ccccc2n2c(CCC(=O)NCC3CCCO3)nnc12 nan
2220688 20521 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
CHEMBL1307526 20521 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 0 6 4.3 Cc1ccc(-c2cc(C(=O)N3CCN(c4ncccn4)CC3)c3cc(Br)ccc3n2)o1 nan
2962628 20612 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
CHEMBL1308267 20612 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 5 5.0 CCOc1cc(C2NC(=O)NC(c3ccccc3)=C2C(=O)c2ccccc2)c(Br)cc1OCC(=O)O nan
3774396 20830 3 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
CHEMBL1310138 20830 3 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 1 3 6 1.7 CSc1nc(S)c2[nH]c(S)nc2n1 nan
6247103 21143 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
CHEMBL1312514 21143 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 4.4 COc1cc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc(OC)c1OC nan
2927414 21500 23 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1315953 21500 23 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 8 1.9 CCOCCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
16187669 21848 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1319736 21848 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 11 2 7 3.0 CCC1CCCCN1CCCNC(=O)CCCNC(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 nan
1473386 21956 24 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
CHEMBL1320637 21956 24 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 4 0 7 0.7 CCOC(=O)CSc1nc(=O)n2ccccc2n1 nan
2363935 21997 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
CHEMBL1321001 21997 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 1 8 0.0 Cn1c(N)c(C(=O)COC(=O)CCc2ccccc2)c(=O)n(C)c1=O nan
1485315 22014 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
CHEMBL1321144 22014 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 5 1.6 CS(=O)(=O)NNC(=O)c1cc2cc3ccccc3nc2s1 nan
20903731 22033 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
CHEMBL1321331 22033 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 9 1 7 2.2 CC1CCN(c2ccc3nnc(CCC(=O)NCCCOC(C)C)n3n2)CC1 nan
16014625 22065 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
CHEMBL1321666 22065 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.3 CC(=O)Nc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 nan
16031994 22240 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
CHEMBL1323264 22240 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 6 5.3 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Cl)c(Cl)c3)nn2)s1 nan
857564 22297 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1323763 22297 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cccc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
1955570 22398 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
CHEMBL1324540 22398 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 5 5.1 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccccc4C)sc3n2)c1 nan
16019112 22422 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
CHEMBL1324746 22422 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 1 8 3.6 Cc1ccccc1NC(=O)Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
20957487 22500 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
CHEMBL1325415 22500 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1 nan
654648 22531 13 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
CHEMBL1325819 22531 13 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.4 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
16411657 22686 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
CHEMBL1327209 22686 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 4 0.9 CC1=NN(c2ccccc2)C(=O)C1/C=C1/NC(=S)NC1=O nan
3725176 22909 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
CHEMBL1329088 22909 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3cccc(C)c3)n2)cc1 nan
2965680 23812 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
CHEMBL1336138 23812 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 4 4.4 CC(NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12)C1CCCO1 nan
2928436 23841 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
CHEMBL1336360 23841 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 2 8 1.7 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1Cc1ccco1 nan
16023198 24066 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1338308 24066 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.0 Cc1nnc(SCC(=O)NCc2cccc(F)c2)c2nn(-c3ccccc3)c(C)c12 nan
4907461 24184 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
CHEMBL1339392 24184 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 5 3.7 CCCCNc1ncnc2sc3c(c12)CCN(CCC)C3 nan
4173573 24629 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1343182 24629 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 2 8 0.8 Cc1cccn2c(=O)c3cc(C(N)=S)c(=N)n(CCCN4CCOCC4)c3nc12 nan
2439152 24642 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
CHEMBL1343295 24642 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 0 5 2.2 Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1 nan
4918386 24992 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
CHEMBL1346435 24992 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 6 2.5 Cc1cc(CNC(=O)C(C)n2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
20904584 25008 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
CHEMBL1346578 25008 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 9 1.7 Cn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccccn4)CC3)nnc12 nan
6112144 25023 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1346652 25023 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 9 1 7 3.5 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
5181544 25341 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1349309 25341 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 8 3.5 COC(=O)c1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
663780 25419 13 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
CHEMBL1349978 25419 13 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 2 8 2.2 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CCCOC(C)C)c(=O)n2c1 nan
860395 25428 47 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
CHEMBL1350037 25428 47 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 3 3.8 O=C(O)c1cc(-c2cccs2)nc2ccc(F)cc12 nan
1013700 25619 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
CHEMBL1351652 25619 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 0 3 3.6 O=C(COc1ccc2cc(Br)ccc2c1Br)N1CCOCC1 nan
4137672 25763 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
CHEMBL1352828 25763 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 4 4.1 O=C(O)c1ccccc1SCc1cn2cc(Br)ccc2n1 nan
15991076 26060 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
CHEMBL1355303 26060 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 6.6 COc1cc2ccccc2cc1C(=O)Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1 nan
16019626 26144 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
CHEMBL1356419 26144 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 8 3.2 Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c(C)c1 nan
16033238 26196 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
CHEMBL1357134 26196 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 5 5.6 Cc1cccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1C nan
4084525 26513 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
CHEMBL1360386 26513 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 0 6 3.9 CCOC(=O)c1sc2nc(C)nc(N3CCCCC3C)c2c1C nan
1130278 26543 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
CHEMBL1360712 26543 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 7 1 6 4.0 Cc1ccc(NC(=O)CSc2nnc(COc3ccccc3C)o2)cc1 nan
2112396 26985 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
CHEMBL1364577 26985 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 7 4.0 CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccc(-c3nc4ccc(C)cc4s3)cc2)c1 nan
3244890 27770 14 None -5 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1370669 27770 14 None -5 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.7 O=C(O)CCc1ccc(-c2ccc(Br)cc2)o1 nan
135443907 28115 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
CHEMBL1373145 28115 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 2 9 4.5 CCOc1ccc2nc(NC(=O)CSc3nc(O)c(C#N)c(-c4ccccc4)n3)sc2c1 nan
16018180 28117 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
CHEMBL1373157 28117 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(OC)c(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)c1 nan
2727621 28219 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
CHEMBL1373780 28219 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 7 3.3 CSc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 nan
16019289 28461 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
CHEMBL1375486 28461 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 5 4.9 Cc1ccc(NC(=O)CSc2ccc(-c3cccs3)nn2)cc1Cl nan
2361888 28622 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
CHEMBL1377052 28622 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc(O)c(C(=O)OCC(=O)N2CCCC2)c1 nan
887924 28706 9 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
CHEMBL1377850 28706 9 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 4 4.8 Cc1ccc2c(Cl)c(C(=O)Nc3ccc4c(c3)OCO4)sc2c1 nan
135527311 29195 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
CHEMBL1382080 29195 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 8 3.7 COC(=O)CSc1nc(O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n1 nan
15987888 29460 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1384448 29460 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 4.8 CCN(CC)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
54710218 29757 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
CHEMBL1386873 29757 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 4 3.7 Cc1ccc(Sc2c(O)c3ccccc3n(C)c2=O)cc1 nan
4047539 29956 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1388441 29956 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 8 0.8 CCOC(=O)CC1C(=O)NCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
733870 30072 37 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
CHEMBL1389324 30072 37 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 1 4 3.6 CC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C nan
829950 30186 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
CHEMBL1390362 30186 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 5 1.6 CN(C)S(=O)(=O)c1cccc(-c2cn3cccnc3n2)c1 nan
5027542 30230 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1390760 30230 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 7 1.5 O=C(CN1C(=O)C2CC=CCC2C1=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
3634961 30344 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
4315628 30344 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
CHEMBL1391748 30344 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 6 3.7 Cc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)cc1 nan
5898126 30376 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
CHEMBL1392030 30376 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 6 4.1 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1 nan
4531942 30413 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1392325 30413 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 11 0.0 CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
1102249 30473 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
CHEMBL1392808 30473 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 2 4 4.5 O=C(Nc1ccc(Br)cn1)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 nan
16018254 30974 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
CHEMBL1398599 30974 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 2 1 4 1.1 CNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
16873489 31105 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
CHEMBL1399932 31105 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 8 2.5 O=[N+]([O-])c1ccccc1S(=O)(=O)Nc1cccc(-c2ccc3nncn3n2)c1 nan
20957244 31260 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1401299 31260 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 0 9 2.5 CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
5053439 31275 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
CHEMBL1401405 31275 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 6 1.2 COC(CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1)OC nan
5734701 31472 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
CHEMBL1403145 31472 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1 nan
5302177 31558 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
CHEMBL1404020 31558 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 0 5 2.0 O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 nan
1504305 31761 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
CHEMBL1405977 31761 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 5 0 7 1.7 Cc1cc(C)n(C(=O)CCCn2cc([N+](=O)[O-])cn2)n1 nan
5221227 31991 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
CHEMBL1407863 31991 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 10 -0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCN4CCOCC4)c3nc12 nan
975666 32128 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
CHEMBL1408899 32128 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 7 1.6 Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
3152548 32144 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
CHEMBL1409014 32144 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1)c1ccco1 nan
3147984 32225 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
CHEMBL1409671 32225 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 2.5 CCN(CC)C(=O)CSc1nnc2c3ccccc3n(C)c2n1 nan
2740105 32294 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
CHEMBL1410151 32294 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 0 4 3.3 N#Cc1c(N2CCCC2)nsc1-c1ccccc1 nan
2965406 32299 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1410223 32299 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 5 4.1 O=C(NCCCn1ccnc1)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
609181 32483 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
CHEMBL1411818 32483 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 1 3 4.1 CC1(C(=O)Nc2nc3ccccc3s2)CC1(Br)Br nan
2328662 32604 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
CHEMBL1412731 32604 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 7 2.6 CCOC(=O)Cc1csc(-n2sc3ccccc3c2=O)n1 nan
716956 32845 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
CHEMBL1414686 32845 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.5 COc1cc(-c2oc3ccc(C)cc3c(=O)c2O)cc(OC)c1OC nan
16019291 33188 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
CHEMBL1417757 33188 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 0 4 5.2 Clc1cccc(CSc2ccc(-c3cccs3)nn2)c1 nan
17581531 33210 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
CHEMBL1417902 33210 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 7 3.5 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCCS3 nan
1505908 33411 11 None -21 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
CHEMBL1419634 33411 11 None -21 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 1.5 Cc1c(F)cccc1NS(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C nan
2138543 33698 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
CHEMBL1422079 33698 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
3937026 34261 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
CHEMBL1426645 34261 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.5 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCC1 nan
5909825 34904 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1432124 34904 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 1 9 2.5 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
16011119 35184 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
CHEMBL1435058 35184 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.2 Cc1ccc(CNC(=O)C(C)n2nc(C)n3c(cc4sccc43)c2=O)cc1 nan
16018536 35310 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
CHEMBL1436706 35310 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 5 5.2 O=C(NCc1cccs1)c1ccc2c(c1)sc1nc(-c3ccccc3)cn12 nan
16011654 35316 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
CHEMBL1436776 35316 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 5.8 Cc1ccc(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)cc1 nan
790330 35541 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
CHEMBL1439016 35541 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2nc(C)cc(S)c2c1 nan
22333977 35562 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
CHEMBL1439223 35562 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 10 2 9 1.0 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)c(OC)c1 nan
974773 35727 8 None -19 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
CHEMBL1440675 35727 8 None -19 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 1 2 2 2.9 O=C(O)c1ccc2cccc(Cl)c2c1O nan
1048151 36224 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1445229 36224 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 3.8 COc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
16407102 36230 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
CHEMBL1445287 36230 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 8 1 9 2.8 COc1ccc2c(c1OC)c(=O)n1c3ccc(OC(C)C(=O)NCCN4CCOCC4)cc3c3ccnc2c31 nan
3244615 36639 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
CHEMBL1448799 36639 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 8 1.2 O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)NCCC(=O)N1CCC2(CC1)OCCO2 nan
5333438 36740 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
CHEMBL1449557 36740 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 3 5 0.9 O=C(O)/C=C\C(=O)Nc1cc(O)ccc1[N+](=O)[O-] nan
946874 37155 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
CHEMBL1452913 37155 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 8 2.2 COC(=O)CSc1nc2ccccc2nc1SCC(=O)OC nan
15990397 37221 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
CHEMBL1453389 37221 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 7 2.2 COc1cc(NC(=O)c2nc3ccccc3n(C)c2=O)cc(OC)c1OC nan
2072948 37366 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
CHEMBL1454562 37366 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 4 3.4 Brc1ccc2ncnc(NCc3cccnc3)c2c1 nan
20957239 37714 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
CHEMBL1457707 37714 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 5 1 8 2.5 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1F nan
8031083 37910 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
CHEMBL1459326 37910 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 7 2.1 CCOC(=O)CCc1c(C)c2ccc3c(c2oc1=O)CN(CCCO)CO3 nan
1947745 38324 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
1947746 38324 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
CHEMBL1462881 38324 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 7 1 3 4.5 CCCCc1c(C)nc2ccccc2c1SCCC(=O)O nan
3593326 38346 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
CHEMBL1463045 38346 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 0 8 1.1 CCOC(=O)C1=NN(c2ccc([N+](=O)[O-])cc2)CC1C(=O)OC nan
3889908 38430 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
663903 38430 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
CHEMBL1463781 38430 15 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 10 1 7 4.1 CCN(CC)CCCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1ccncc1 nan
4834173 38652 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
CHEMBL1465419 38652 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 6 2.7 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cccc(C#N)c2)c1 nan
2124679 38742 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
CHEMBL1466120 38742 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.7 O=C(COc1ncnc2ccc(Br)cc12)NCc1ccco1 nan
5840379 38878 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
CHEMBL1467214 38878 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 4 1 9 0.8 Cc1cccn2c(=O)c(/C=C(\C#N)C(=O)NC3CCS(=O)(=O)C3)c(N3CC(C)OC(C)C3)nc12 nan
2824481 39030 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
CHEMBL1468502 39030 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 5 3.9 N#Cc1c(N2CCSCC2)nsc1-c1ccccc1Cl nan
5911323 39154 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
CHEMBL1469507 39154 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.0 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(C)cc2)cc1 nan
3186594 39335 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1471097 39335 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
5302637 39544 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
CHEMBL1473111 39544 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 4 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2)cc1 nan
16009440 39609 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
CHEMBL1474025 39609 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 7 4.0 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1C nan
16018838 39612 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
CHEMBL1474070 39612 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 0 5 4.9 Clc1cccc(CSc2nncn3c2cc2sccc23)c1 nan
16033266 39734 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1475712 39734 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.3 Cc1c(C(=O)NC(C)c2ccccc2)sc2ncnc(N(C)C3CCCCC3)c12 nan
16030277 39738 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
CHEMBL1475778 39738 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 nan
16018142 39761 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
CHEMBL1476187 39761 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 6 1 2 4.0 Cn1cc(CCCC(=O)NCc2ccc(F)cc2)c2ccccc21 nan
16018630 39769 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
CHEMBL1476304 39769 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 6 4.0 O=C(CSc1nncn2c1cc1occc12)Nc1ccc(F)c(Cl)c1 nan
16018040 39782 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1476501 39782 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 6 3.1 COc1ccc(OC)c(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
135407487 39796 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
CHEMBL1476621 39796 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(CNC(=O)CSc2nc3[nH]nc(C)c3c(=N)n2-c2ccccc2Cl)cc1 nan
676907 39895 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
CHEMBL1477596 39895 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 205 1 1 3 2.8 COc1ccc2c(C)cc(S)nc2c1 nan
16018964 40133 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1479750 40133 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.2 CCC(C)NC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16018270 40629 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
CHEMBL1484019 40629 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 5 5.5 CC(=O)Nc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
4613858 41025 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
CHEMBL1487438 41025 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 1 2 7 0.9 COC(=O)c1sc2[nH]c(=S)n(N)c(=O)c2c1C nan
1173795 41174 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1488482 41174 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 2 9 1.9 CCCn1c(SCC(=O)Nc2ccc(NC(=O)CC)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
3152454 41206 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
CHEMBL1488709 41206 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 3 8 0.4 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1CCCO nan
1294912 41645 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
CHEMBL1491898 41645 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 2 8 3.8 COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
3944710 41652 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
CHEMBL1491951 41652 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 5 2 8 2.1 O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCOCC1)c1cc(O)nc2ccccc12 nan
2958357 41978 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
CHEMBL1494894 41978 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 6 2.9 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCC3 nan
3601528 42012 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
CHEMBL1495241 42012 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 2 7 5.3 COc1ccc(C(=O)Nc2nc3n(n2)C(c2ccc(Cl)cc2)C=C(c2ccccc2)N3)cc1OC nan
3120647 42019 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
CHEMBL1495306 42019 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 3 1 4 6.9 O=C(Nc1ccc2oc(-c3cc(Br)ccc3Cl)nc2c1)c1cc2ccccc2o1 nan
3296097 42116 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
CHEMBL1496299 42116 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 5 1 9 4.1 CCc1ccc(-n2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3nncc-3c2O)cc1 nan
2175955 42602 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
CHEMBL1500554 42602 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3cccnc3)cc2)c1C nan
2868511 42630 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
CHEMBL1500746 42630 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 4 3.5 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(C)cc2)cc1 nan
3146565 42865 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1502935 42865 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 4.0 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
2998667 43037 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1504458 43037 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 1 9 -1.9 CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
2497236 43235 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
CHEMBL1506154 43235 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 6 4.6 CCOc1ccc(-c2nc(-c3cccs3)c(CC(=O)O)s2)cc1OC nan
1442564 43642 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1509687 43642 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 3.5 COC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
6305743 43653 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1509795 43653 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 7 1 5 3.2 COCCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
15988981 43936 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1512541 43936 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 8 2 7 4.1 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(=O)NCc3ccccc3Cl)c(=O)c3sccc32)c(C)c1 nan
1116224 44054 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
CHEMBL1514415 44054 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 7 1.1 Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(C(F)(F)F)c2)n(C)c1=O nan
16018038 44128 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1515402 44128 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 5 3.8 CSc1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
16016056 44158 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
CHEMBL1515947 44158 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 7 5.0 COc1ccccc1-c1noc(-c2ccc(NCCc3ccccc3)c([N+](=O)[O-])c2)n1 nan
5069160 44232 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
CHEMBL1516839 44232 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
5389765 44446 9 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
CHEMBL1518887 44446 9 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 8 1 6 3.1 COCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)cc2)C1c1cccnc1 nan
1238913 44590 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
CHEMBL1520162 44590 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 0 9 -1.1 Cn1c(=O)c2c(nc(SCC(=O)N3CCOCC3)n2C)n(C)c1=O nan
2165182 44715 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
CHEMBL1521212 44715 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 5 2.9 Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)o1 nan
3111808 44767 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
CHEMBL1521616 44767 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1 nan
20957509 44889 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1522776 44889 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 11 2 8 1.8 COc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
4126696 44904 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
CHEMBL1522905 44904 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 5 5.9 COc1ccc(-n2cc(-c3ccccc3)nc2SCC(=O)Nc2ccccc2)cc1Cl nan
2561590 45263 6 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
CHEMBL1526230 45263 6 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 0 8 4.1 Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 nan
15991183 45414 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1527553 45414 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 1 4 6.8 O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccc(-c2ccc(Br)cc2)o1 nan
16014288 45766 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
CHEMBL1530646 45766 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 2 8 3.8 Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)c3nc(SC(C)C)ncc3Cl)cc2)n1 nan
6078364 45775 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
CHEMBL1530717 45775 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)cc1 nan
950608 46161 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
CHEMBL1534139 46161 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 1.5 N#C/C(=C\c1c(N2CCCCCC2)nc2ccccn2c1=O)C(N)=O nan
5310696 46175 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
CHEMBL1534309 46175 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 10 1 6 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OCC(C)C)cc2C)C1c1cccnc1 nan
1856407 46411 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
CHEMBL1536792 46411 20 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 1.1 CCOC(=O)N1CCN(c2nc3c(C)cccn3c(=O)c2C=O)CC1 nan
1442728 46466 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
CHEMBL1537182 46466 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 4 4.3 CC(C)c1nc(SCC(=O)NC2CCCCC2)c2ccccc2n1 nan
6165328 46711 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
CHEMBL1539268 46711 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 6 4.3 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Cl)cc2)cc1 nan
2944889 46907 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
CHEMBL1540923 46907 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 10 1 7 5.1 CCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccco2)cc1OCC nan
1867273 47385 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
CHEMBL1544770 47385 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
3600899 47416 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
CHEMBL1545051 47416 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 9 4.3 O=c1cc(CSc2nc3nncc-3c(O)n2-c2ccc(Br)cc2)nc2ccc(Br)cn12 nan
135514845 47615 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
CHEMBL1546713 47615 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 8 2.7 CN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
1442627 47822 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
CHEMBL1548632 47822 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 2 6 3.1 CCCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
16016034 48202 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
CHEMBL1552261 48202 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 1 7 4.1 COc1ccccc1-c1noc(-c2ccc(NC(C)C)c([N+](=O)[O-])c2)n1 nan
16017890 48219 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
CHEMBL1552564 48219 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 1.5 COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
16023050 48220 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
CHEMBL1552569 48220 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 3.1 CCNC(=O)C1CCCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)C1 nan
3260331 48277 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
CHEMBL1553312 48277 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 3 4.6 O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)Nc1ccc(Br)cc1 nan
16030436 48352 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
CHEMBL1554451 48352 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 2.9 CC(C)C(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 nan
16016784 48410 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
CHEMBL1555295 48410 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 5.4 CCOC(=O)C1CCCN(C(=O)c2[nH]c3ccccc3c2Sc2ccc(Cl)cc2)C1 nan
16196698 48433 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
CHEMBL1555603 48433 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 7 1.9 Cc1cc2nnc(SCC(=O)N(C)C3CCS(=O)(=O)C3)n2c2ccccc12 nan
2869543 48602 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
CHEMBL1557161 48602 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 3.9 CCOC(=O)c1ccc(Nc2nnc(C)c3ccccc23)cc1 nan
1272771 48642 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
CHEMBL1557478 48642 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 6 5.4 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C)cc4C)sc3n2)cc1OC nan
3239737 48779 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
CHEMBL1558668 48779 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 7 1.4 Cc1nn(C(C)C(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 nan
1503106 48970 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
CHEMBL1560348 48970 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 5 3.1 Cc1cc(CNC(=O)COc2ccc([N+](=O)[O-])cc2)c2ccccc2n1 nan
2456723 49255 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
CHEMBL1562996 49255 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 8 2 8 3.7 CCOC(=O)c1cc(-c2ccccc2)sc1NC(=O)COC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 nan
3221518 49364 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1563919 49364 5 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 8 1 5 3.8 CCCNC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
2952819 49429 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
CHEMBL1564585 49429 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.3 O=C(Cn1nc(-c2cccc([N+](=O)[O-])c2)c2ccccc2c1=O)NCC1CCCO1 nan
2869470 49626 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
CHEMBL1566109 49626 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 0 5 3.6 Cc1nnc(Oc2ccc([N+](=O)[O-])cc2)c2ccccc12 nan
16008434 49716 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
CHEMBL1566810 49716 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 5 4.7 O=C(c1ccc(Cl)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCCO3 nan
1017457 49824 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
CHEMBL1567667 49824 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 11 0.2 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC3CCCCC3)n2C)n(C)c1=O nan
2912191 49914 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
CHEMBL1568384 49914 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 4.4 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)cc2)o1 nan
665555 50211 8 None -1 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1570874 50211 8 None -1 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 5 4.9 Cc1nc(SCC(=O)Nc2ccc(C)c(F)c2)c2oc3ccccc3c2n1 nan
4333346 50410 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
CHEMBL1572841 50410 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 4 4.3 COc1ccc(CCNC(=O)CSc2ccc3ccccc3c2)cc1OC nan
20957497 50616 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
CHEMBL1574892 50616 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 10 2 7 2.1 Cc1ccc(CNC(=O)CCc2nnc3ccc(NCCCN4CCCC4=O)nn23)cc1 nan
1938572 50832 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1576963 50832 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 1 6 3.6 O=C(COc1ccccc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
1632391 50986 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
CHEMBL1578274 50986 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 3 4 2.0 O=C(O)CCC(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
3504887 51038 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
CHEMBL1578618 51038 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 7 1.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC1 nan
20903631 51044 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
CHEMBL1578662 51044 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 0 9 1.2 COc1cccc(N2CCN(c3ccc4nnc(CCC(=O)N5CCN(C)CC5)n4n3)CC2)c1 nan
16475 51687 43 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
CHEMBL1584156 51687 43 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 4 4 1.9 Nc1ccc(-c2ccc(N)c(C(=O)O)c2)cc1C(=O)O nan
1997175 51734 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
CHEMBL1584587 51734 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 0 7 0.9 CN1CCN(c2nc3ccccn3c(=O)c2C=C(C#N)C#N)CC1 nan
20881207 51978 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
CHEMBL1586569 51978 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 10 1 8 2.5 CC(C)OCCCn1c(=O)c2ccccc2n2c(CCC(=O)NCc3ccccn3)nnc12 nan
3186634 51979 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1586576 51979 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 0 9 -1.2 CN1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
658021 52253 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
CHEMBL1588879 52253 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 0 5 3.0 CSC1=NP(=S)(SC)N(C)c2nc3n(c21)CCC3 nan
7190667 52363 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
CHEMBL1589799 52363 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1cccc(F)c1 nan
16030609 52406 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
CHEMBL1590288 52406 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 0 5 5.7 CCN(C(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1)c1cccc(C)c1 nan
6221827 52436 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
CHEMBL1590750 52436 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.0 COc1ccc(CNC(=O)Cc2c(C)c3c(O)cc(C)cc3oc2=O)cc1 nan
16030275 52518 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1591718 52518 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 0 4 4.9 CCCCN(C)C(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16031876 52570 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
CHEMBL1592401 52570 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 0 5 5.0 CCC1CCCCN1Cc1cn2c(-c3ccc(Br)cc3)nnc2s1 nan
5768121 52782 11 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
CHEMBL1594882 52782 11 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 6 4.6 Cc1cc(OCC(C)C)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
4968658 52892 6 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1595841 52892 6 None -5 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3ccc(Cl)cc3)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
4875333 53517 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
CHEMBL1601617 53517 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 4 3.5 CCn1c2ccccc2c2nc3cc(C(=O)O)ccc3nc21 nan
15988911 53834 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 7 4.2 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3c(C)cc(C)cc3C)c2=O)c1 nan
CHEMBL1604412 53834 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 7 4.2 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3c(C)cc(C)cc3C)c2=O)c1 nan
824096 53926 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 220 0 2 5 1.2 N=c1c2c3c(sc2ncn1N)CCCC3 nan
CHEMBL1605294 53926 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 220 0 2 5 1.2 N=c1c2c3c(sc2ncn1N)CCCC3 nan
16020886 54014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1ccc(CSc2nc3cccnc3n2Cc2ccc(C(=O)NC3CCCCC3)cc2)cc1 nan
CHEMBL1605955 54014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1ccc(CSc2nc3cccnc3n2Cc2ccc(C(=O)NC3CCCCC3)cc2)cc1 nan
3973561 54387 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 7 4.1 COc1ccc2cc(C(=O)COC(=O)COc3ccc4c(C)cc(=O)oc4c3)ccc2c1 nan
CHEMBL1608925 54387 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 7 4.1 COc1ccc2cc(C(=O)COC(=O)COc3ccc4c(C)cc(=O)oc4c3)ccc2c1 nan
4916122 54506 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.7 Cc1cccc(NC(=O)C(C)n2cc([N+](=O)[O-])cn2)n1 nan
CHEMBL1609905 54506 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.7 Cc1cccc(NC(=O)C(C)n2cc([N+](=O)[O-])cn2)n1 nan
3151454 54691 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 2 8 1.4 COCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1611459 54691 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 2 8 1.4 COCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
2810155 54882 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 5 3.6 Cc1ccccc1C(=O)Nc1nc2c(C)csc2c(=O)s1 nan
CHEMBL1613272 54882 6 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 5 3.6 Cc1ccccc1C(=O)Nc1nc2c(C)csc2c(=O)s1 nan
6489921 55350 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1384004 55350 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1618913 55350 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 0 2 3.4 CCCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
135415554 55781 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
CHEMBL1494334 55781 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
CHEMBL1622628 55781 3 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 7 4.4 Cc1nn(CCc2nc(-c3ccco3)cs2)c2nc(O)cc(C(F)(F)F)c12 nan
24792259 55841 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1517470 55841 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
CHEMBL1623157 55841 1 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 3 6 2.5 Nc1c(S(=O)(=O)O)cc(NC(=O)c2ccccc2)c2c1C(=O)c1ccccc1C2=O nan
4323731 107697 4 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 3 3 4 5.9 Oc1c(Br)cc(/C=N/c2ccc3[nH]c(-c4ccccc4)nc3c2)c(O)c1Br nan
CHEMBL3190756 107697 4 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 3 3 4 5.9 Oc1c(Br)cc(/C=N/c2ccc3[nH]c(-c4ccccc4)nc3c2)c(O)c1Br nan
4073001 108714 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 8 2.6 COC(=O)Cn1/c(=N/C(=O)c2ccc(OC)c(OC)c2)sc2cc(OC)ccc21 nan
CHEMBL3208346 108714 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 8 2.6 COC(=O)Cn1/c(=N/C(=O)c2ccc(OC)c(OC)c2)sc2cc(OC)ccc21 nan
6870745 109096 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 0 7 2.1 Cc1nc2ccccc2c(=O)n1/N=C/c1ccc([N+](=O)[O-])o1 nan
CHEMBL3213340 109096 10 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 0 7 2.1 Cc1nc2ccccc2c(=O)n1/N=C/c1ccc([N+](=O)[O-])o1 nan
2941245 146849 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.8 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccccc3)C2c2cccnc2)o1 nan
CHEMBL392515 146849 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 3.8 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccccc3)C2c2cccnc2)o1 nan
1016096 191795 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
CHEMBL519824 191795 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 2.7 Cc1cc(C)nc(NS(=O)(=O)c2ccc(N3C(=O)c4ccccc4C3=O)cc2)n1 nan
726062 197039 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
CHEMBL1583656 197039 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
CHEMBL567206 197039 48 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 0 2 5 2.6 Oc1nc(S)nc2sc3c(c12)CCCC3 nan
2998030 31518 6 None - 1 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 3 6 0.5 COCCNC(=O)NC(=O)COC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 nan
CHEMBL1403647 31518 6 None - 1 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 3 6 0.5 COCCNC(=O)NC(=O)COC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 nan
975392 42471 9 None -1 2 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 1 2 4.3 Cc1cc(Br)c2nc3c(c(C(=O)O)c2c1)CCCCC3 nan
CHEMBL1499411 42471 9 None -1 2 Human 5.7 pPotency = 5.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 1 2 4.3 Cc1cc(Br)c2nc3c(c(C(=O)O)c2c1)CCCCC3 nan
16019550 10707 14 None -131 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.3 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
CHEMBL1170886 10707 14 None -131 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.3 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
4204374 19573 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 6 2 6 3.4 COc1cc2nc(S)nc(NCCC(C)C)c2cc1OC nan
CHEMBL1299978 19573 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 6 2 6 3.4 COc1cc2nc(S)nc(NCCC(C)C)c2cc1OC nan
2421557 19722 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 0 7 3.6 COC(=O)CCc1c(C)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccn12 nan
CHEMBL1301080 19722 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 8 0 7 3.6 COC(=O)CCc1c(C)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccccn12 nan
22548258 20293 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1 nan
CHEMBL1305765 20293 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1 nan
16194269 20482 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 7 1 8 2.4 O=C(CSC1=Nc2ccccc2C2=NC(CC(=O)N3CCN(c4ccccc4)CC3)C(=O)N12)NCC1CCCO1 nan
CHEMBL1307199 20482 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 7 1 8 2.4 O=C(CSC1=Nc2ccccc2C2=NC(CC(=O)N3CCN(c4ccccc4)CC3)C(=O)N12)NCC1CCCO1 nan
3740686 21110 14 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)no1 nan
CHEMBL1312274 21110 14 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(F)cc2)no1 nan
4465171 21258 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCCC2)c1 nan
CHEMBL1313361 21258 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 O=C(CSc1ncnc2ccccc12)Nc1cccc(S(=O)(=O)N2CCCC2)c1 nan
2197541 21309 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.3 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCC3)c2C#N)cc1 nan
CHEMBL1313695 21309 10 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.3 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCC3)c2C#N)cc1 nan
2679228 21364 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 7 4.0 COc1ccc2oc(C(=O)Nc3nc4ccc(S(C)(=O)=O)cc4s3)c(C)c2c1 nan
CHEMBL1314240 21364 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 4 1 7 4.0 COc1ccc2oc(C(=O)Nc3nc4ccc(S(C)(=O)=O)cc4s3)c(C)c2c1 nan
16034516 21396 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.6 Cc1nnc(SCC(=O)NCc2ccccc2F)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1314574 21396 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.6 Cc1nnc(SCC(=O)NCc2ccccc2F)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
135419125 21427 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 3 5.7 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2ccccc2)C1 nan
CHEMBL1315137 21427 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 3 5.7 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2ccccc2)C1 nan
16012610 21434 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 4 0 10 4.0 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(Cl)cc5)s4)c3nc12 nan
CHEMBL1315199 21434 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 4 0 10 4.0 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(Cl)cc5)s4)c3nc12 nan
4119285 21481 13 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
CHEMBL1315733 21481 13 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 2 0 7 2.2 Cn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(C)(=O)=O)ccc21 nan
24892214 21497 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 8 2.2 COc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1315929 21497 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 8 2.2 COc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
7599144 21505 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 5 3.1 Cc1cc(NC(=O)c2cccn(Cc3cccc(Cl)c3)c2=O)no1 nan
CHEMBL1315995 21505 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 5 3.1 Cc1cc(NC(=O)c2cccn(Cc3cccc(Cl)c3)c2=O)no1 nan
16018244 21669 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3ccccc3Cl)cc1CC2 nan
CHEMBL1318247 21669 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 1 5 3.5 Cc1c(C(=O)NCCN(C)C)oc2c1-c1nn(Cc3ccccc3Cl)cc1CC2 nan
15944876 21790 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1319259 21790 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16010992 21874 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 2.6 CCc1cc2c(cc3c(=O)n(CC(=O)NCCc4ccc(OC)c(OC)c4)ncn32)s1 nan
CHEMBL1319991 21874 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 2.6 CCc1cc2c(cc3c(=O)n(CC(=O)NCCc4ccc(OC)c(OC)c4)ncn32)s1 nan
4164390 21961 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 5 6.1 CC(C)OC(=O)c1c(NC(=O)C2c3ccccc3Oc3ccccc32)sc2c1CCCC2 nan
CHEMBL1320657 21961 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 5 6.1 CC(C)OC(=O)c1c(NC(=O)C2c3ccccc3Oc3ccccc32)sc2c1CCCC2 nan
25102515 21983 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 4 4.1 Cc1cc(=O)oc2cc(NC(=O)COc3cccc(C(F)(F)F)c3)ccc12 nan
CHEMBL1320916 21983 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 1 4 4.1 Cc1cc(=O)oc2cc(NC(=O)COc3cccc(C(F)(F)F)c3)ccc12 nan
794839 22038 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 4 2.8 Sc1nnc(-c2cccc(Br)c2)o1 nan
CHEMBL1321356 22038 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 4 2.8 Sc1nnc(-c2cccc(Br)c2)o1 nan
16018780 22040 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4cccc(Cl)c4)nnc(C)n32)o1 nan
CHEMBL1321426 22040 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 0 5 5.0 Cc1cc2c(cc3c(SCc4cccc(Cl)c4)nnc(C)n32)o1 nan
3996443 22090 6 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 10 -0.7 Cn1c(N)c(C(=O)COC(=O)COc2ccccc2C#N)c(=O)n(C)c1=O nan
CHEMBL1321877 22090 6 None -7 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 10 -0.7 Cn1c(N)c(C(=O)COC(=O)COc2ccccc2C#N)c(=O)n(C)c1=O nan
16009867 22332 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.5 CCOc1ccccc1NC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1324000 22332 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.5 CCOc1ccccc1NC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21 nan
1442375 22438 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 4.1 CC(C)(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1324849 22438 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 4.1 CC(C)(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
22517548 22553 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 1.6 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Br nan
CHEMBL1326013 22553 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 1.6 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Br nan
20927538 22667 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 0 7 1.3 CN(Cc1ccco1)C(=O)Cn1cc(S(=O)(=O)N2CCCC2)c(S(=O)(=O)N2CCCC2)c1 nan
CHEMBL1327078 22667 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 0 7 1.3 CN(Cc1ccco1)C(=O)Cn1cc(S(=O)(=O)N2CCCC2)c(S(=O)(=O)N2CCCC2)c1 nan
2645777 22762 15 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 3 4.4 N#Cc1c(S)nc(-c2ccccc2Cl)c2c1CCCC2 nan
CHEMBL1327817 22762 15 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 3 4.4 N#Cc1c(S)nc(-c2ccccc2Cl)c2c1CCCC2 nan
2816375 22990 28 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 1 7 1.7 CCOC(=O)c1nnn2c1nc(S)c1ccccc12 nan
CHEMBL1329724 22990 28 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 1 7 1.7 CCOC(=O)c1nnn2c1nc(S)c1ccccc12 nan
3151322 22999 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.0 N=c1c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1329807 22999 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.0 N=c1c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
16030826 23148 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 2 5 2.9 NC(=O)C1CCN(C(=O)c2ccccc2NC(=O)c2nsc3ccccc23)CC1 nan
CHEMBL1330985 23148 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 2 5 2.9 NC(=O)C1CCN(C(=O)c2ccccc2NC(=O)c2nsc3ccccc23)CC1 nan
2815453 23387 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 0 5 0.3 Cn1c2c(c(=O)n3ncnc13)CCCC2 nan
CHEMBL1332830 23387 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 0 5 0.3 Cn1c2c(c(=O)n3ncnc13)CCCC2 nan
16019110 23396 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 3.3 O=C(Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21)Nc1ccccc1 nan
CHEMBL1332893 23396 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 3.3 O=C(Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21)Nc1ccccc1 nan
16018748 23399 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 0 5 4.7 Cc1nnc(SCc2ccc(Cl)cc2)c2cc3occc3n12 nan
CHEMBL1332908 23399 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 0 5 4.7 Cc1nnc(SCc2ccc(Cl)cc2)c2cc3occc3n12 nan
876371 23463 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 4 2.2 Cc1cc(/C=C2/C(=O)NC(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
CHEMBL1333432 23463 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 4 2.2 Cc1cc(/C=C2/C(=O)NC(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
16031513 23869 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.0 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(C(F)(F)F)c3)s2)cc1 nan
CHEMBL1336578 23869 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.0 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(C(F)(F)F)c3)s2)cc1 nan
16011266 24051 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 3.5 Cc1cccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)c1 nan
CHEMBL1338231 24051 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 3.5 Cc1cccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)c1 nan
16009346 24125 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 4 5.1 CCc1ccc2c(c1)c(=O)c(C(=O)c1ccc(C)cc1)cn2CC(=O)Nc1ccccc1C nan
CHEMBL1338819 24125 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 4 5.1 CCc1ccc2c(c1)c(=O)c(C(=O)c1ccc(C)cc1)cn2CC(=O)Nc1ccccc1C nan
1451340 24244 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 7 1 7 4.2 Cc1nonc1NC(=O)CSc1nc(CCC2CCCC2)nc2ccccc12 nan
CHEMBL1339937 24244 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 7 1 7 4.2 Cc1nonc1NC(=O)CSc1nc(CCC2CCCC2)nc2ccccc12 nan
1173483 24454 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 7 4.1 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1nc(C)c(C)s1)OCO3 nan
CHEMBL1341833 24454 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 7 4.1 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1nc(C)c(C)s1)OCO3 nan
3208214 24724 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2cc(C)cc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1344061 24724 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2cc(C)cc(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
1442646 24912 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 CCCc1nc(SCC(=O)N2CCc3ccccc3C2)c2ccccc2n1 nan
CHEMBL1345722 24912 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 CCCc1nc(SCC(=O)N2CCc3ccccc3C2)c2ccccc2n1 nan
2322587 24932 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 9 1 6 1.7 CCN(CC)S(=O)(=O)c1ccc(C(=O)OCCNC(=O)c2cccnc2)cc1 nan
CHEMBL1345885 24932 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 9 1 6 1.7 CCN(CC)S(=O)(=O)c1ccc(C(=O)OCCNC(=O)c2cccnc2)cc1 nan
3475758 24952 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc(OC)c1OC nan
CHEMBL1346015 24952 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc(OC)c1OC nan
911360 24995 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 0 1 4 1.3 Cn1c(O)nc2c(Cl)nccc21 nan
CHEMBL1346457 24995 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 183 0 1 4 1.3 Cn1c(O)nc2c(Cl)nccc21 nan
745324 25049 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 5 4.4 Cc1ccc(NC(S)=Nc2cccc(-c3nnc(S)o3)c2)cc1 nan
CHEMBL1346824 25049 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 5 4.4 Cc1ccc(NC(S)=Nc2cccc(-c3nnc(S)o3)c2)cc1 nan
664458 25090 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 4 0 6 4.4 O=C(CSc1ncnc2c1oc1ccccc12)c1cccs1 nan
CHEMBL1347130 25090 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 4 0 6 4.4 O=C(CSc1ncnc2c1oc1ccccc12)c1cccs1 nan
866600 25126 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 0 6 1.7 CCN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1347433 25126 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 0 6 1.7 CCN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
2158422 25291 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 7 2.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)CC1 nan
CHEMBL1348934 25291 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 7 2.6 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)CC1 nan
7711373 25327 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 2.9 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccco1 nan
CHEMBL1349179 25327 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 1 5 2.9 O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)c1ccco1 nan
20920345 25674 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1352171 25674 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
3742858 25885 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Br)cc2)no1 nan
CHEMBL1353643 25885 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(Br)cc2)no1 nan
16009768 26014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 9 2 6 5.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)COc2cccc(OC)c2)cc1 nan
CHEMBL1354836 26014 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 9 2 6 5.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)COc2cccc(OC)c2)cc1 nan
16022445 26021 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 1 3 4.8 CC1Cn2c(C(=O)NCc3cccc(Br)c3)cc3cccc(c32)S1 nan
CHEMBL1354873 26021 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 3 1 3 4.8 CC1Cn2c(C(=O)NCc3cccc(Br)c3)cc3cccc(c32)S1 nan
16024821 26095 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccc(Cl)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1355809 26095 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccc(Cl)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
5292880 26105 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 4 6.5 COc1cc(/C=C(\C#N)c2nc3ccccc3[nH]2)cc(Cl)c1OCc1ccccc1Cl nan
CHEMBL1355927 26105 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 4 6.5 COc1cc(/C=C(\C#N)c2nc3ccccc3[nH]2)cc(Cl)c1OCc1ccccc1Cl nan
7878585 26109 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.9 O=C(CNC(=O)c1ccc(Cl)cc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1356005 26109 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.9 O=C(CNC(=O)c1ccc(Cl)cc1)OCc1cc(=O)n2ccsc2n1 nan
6200344 26181 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 7 1 6 2.7 COc1cccc(/C=C/c2nc(C#N)c(NCCN(C)C)o2)c1 nan
CHEMBL1356982 26181 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 7 1 6 2.7 COc1cccc(/C=C/c2nc(C#N)c(NCCN(C)C)o2)c1 nan
1004107 26369 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 2 5 5.3 CCOc1cccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)c1 nan
CHEMBL1359199 26369 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 2 5 5.3 CCOc1cccc(NC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)c1 nan
16009637 26671 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 6 4.5 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1ccccc1 nan
CHEMBL1361843 26671 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 6 4.5 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1ccccc1 nan
4114478 27023 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.1 COc1cccc(NC(=O)Cn2cc(C(=O)C3CCCCC3)c3ccccc32)c1 nan
CHEMBL1364874 27023 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.1 COc1cccc(NC(=O)Cn2cc(C(=O)C3CCCCC3)c3ccccc32)c1 nan
22641 27272 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 7 0.8 CC(=O)OCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(C)cc21 nan
CHEMBL1367036 27272 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 1 7 0.8 CC(=O)OCCn1c2nc(=O)[nH]c(=O)c-2nc2cc(C)c(C)cc21 nan
2378240 27377 29 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 2 1 4 2.7 Fc1ccccc1-c1nnc(S)n1C1CC1 nan
CHEMBL1367871 27377 29 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 2 1 4 2.7 Fc1ccccc1-c1nnc(S)n1C1CC1 nan
12006141 27705 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 4 4.8 Cc1ccc(CSc2ccc(-c3cccs3)nn2)cc1 nan
CHEMBL1370265 27705 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 0 4 4.8 Cc1ccc(CSc2ccc(-c3cccs3)nn2)cc1 nan
16455091 27817 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 2 8 3.0 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccc(F)cc4)ccc3=O)cc2)c1C nan
CHEMBL1371016 27817 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 2 8 3.0 Cc1noc(NS(=O)(=O)c2ccc(NC(=O)c3nn(-c4ccc(F)cc4)ccc3=O)cc2)c1C nan
135406328 28016 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 1 7 1.3 Cc1cc(C)c2c(O)nc(SCC(=O)N3CCOCC3)nc2n1 nan
CHEMBL1372508 28016 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 1 7 1.3 Cc1cc(C)c2c(O)nc(SCC(=O)N3CCOCC3)nc2n1 nan
2138011 28398 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3ccccc3c2=O)cc1 nan
CHEMBL1375055 28398 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3ccccc3c2=O)cc1 nan
3571741 28403 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 4.6 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1375116 28403 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 4.6 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3)c3cc(Br)ccc3n2)cc1 nan
16025702 28434 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 5.9 CCOc1ccccc1CNC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1 nan
CHEMBL1375311 28434 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 5.9 CCOc1ccccc1CNC(=O)c1ccc(N2Cc3ccccc3Oc3ncccc32)s1 nan
2874807 28924 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 7 4.6 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccc(C)cc3c2=O)C2=C(O)CCCC2=N1 nan
CHEMBL1379763 28924 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 7 4.6 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccc(C)cc3c2=O)C2=C(O)CCCC2=N1 nan
1564382 29104 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 7 1 7 5.8 CCCCn1c(NC(=O)c2ccc(Br)o2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
CHEMBL1381243 29104 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 7 1 7 5.8 CCCCn1c(NC(=O)c2ccc(Br)o2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
666048 29308 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 9 2.0 c1cncc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 nan
CHEMBL1383055 29308 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 9 2.0 c1cncc(-c2nn3c(Cn4nnc5ccccc54)nnc3s2)c1 nan
220464 29310 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 0 2 2.9 Cn1ccc(=S)c2ccccc21 nan
CHEMBL1383064 29310 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 0 2 2.9 Cn1ccc(=S)c2ccccc21 nan
4805097 29323 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 2 0 7 0.4 CC1Cc2ccccc2N1C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1383239 29323 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 2 0 7 0.4 CC1Cc2ccccc2N1C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1186390 29544 12 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 1 0 3 4.7 O=C(Oc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
CHEMBL1385192 29544 12 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 1 0 3 4.7 O=C(Oc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
4877595 29747 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 5 3.8 O=C(CSc1nnc(-c2ccc(F)cc2)c2ccccc12)NCC1CCCO1 nan
CHEMBL1386797 29747 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 5 3.8 O=C(CSc1nnc(-c2ccc(F)cc2)c2ccccc12)NCC1CCCO1 nan
865072 30004 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 4.0 CCOC(=O)CSc1nc(-c2ccccc2)nc2ccccc12 nan
CHEMBL1388860 30004 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 0 5 4.0 CCOC(=O)CSc1nc(-c2ccccc2)nc2ccccc12 nan
2406693 30027 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 8 2.5 COC(=O)c1sc2nc(C)nc(SCC(=O)N3CCC(C(=O)O)CC3)c2c1C nan
CHEMBL1389013 30027 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 8 2.5 COC(=O)c1sc2nc(C)nc(SCC(=O)N3CCC(C(=O)O)CC3)c2c1C nan
1261479 30174 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 2 5 3.5 Cc1cc(C)c2nc(-c3ccccn3)cc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c2c1 nan
CHEMBL1390223 30174 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 2 5 3.5 Cc1cc(C)c2nc(-c3ccccn3)cc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c2c1 nan
16033258 30623 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1c(C(=O)Nc2ccccc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1394084 30623 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1c(C(=O)Nc2ccccc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
16019740 30625 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 8 2.9 CCn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
CHEMBL1394098 30625 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 0 8 2.9 CCn1c(=O)c2sccc2n2c(CCCC(=O)N3CCN(c4ccc(F)cc4)CC3)nnc12 nan
16019075 30653 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 4.4 CC(C)Oc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1394443 30653 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 4.4 CC(C)Oc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
1179391 30815 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(=O)(=O)N4CCCC4)cc3s2)cc1 nan
CHEMBL1396599 30815 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(=O)(=O)N4CCCC4)cc3s2)cc1 nan
16031181 30881 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.3 COc1cc(NC(=O)c2cc3cc4cc(OC)ccc4nc3o2)cc(OC)c1 nan
CHEMBL1397472 30881 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.3 COc1cc(NC(=O)c2cc3cc4cc(OC)ccc4nc3o2)cc(OC)c1 nan
16028170 30919 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 2 3 4.2 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(Cl)c3)cc21 nan
CHEMBL1397995 30919 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 2 3 4.2 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3cccc(Cl)c3)cc21 nan
729756 30942 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 1 3 3.9 Cc1ccc(/C=C(\C#N)C(=O)Nc2ccc(Br)cc2)o1 nan
CHEMBL1398350 30942 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 1 3 3.9 Cc1ccc(/C=C(\C#N)C(=O)Nc2ccc(Br)cc2)o1 nan
16031340 30949 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 3 4.7 CCc1ccc(CNC(=O)c2cnc(N3CCCCC3)c3ccccc23)cc1 nan
CHEMBL1398430 30949 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 3 4.7 CCc1ccc(CNC(=O)c2cnc(N3CCCCC3)c3ccccc23)cc1 nan
15989002 30950 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2cccc(F)c2)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1398440 30950 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2cccc(F)c2)c1=O)NCc1ccc2c(c1)OCO2 nan
16026774 30953 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 2.2 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3Cl)cc(=O)n12 nan
CHEMBL1398452 30953 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 2.2 Cc1csc2nc(COC(=O)CNC(=O)c3ccccc3Cl)cc(=O)n12 nan
24790947 31243 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccc(F)cc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1401193 31243 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccc(F)cc4)CC3)ccc2c1)N1CCCCC1 nan
16017881 31523 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 2.3 CCOc1ccc(NC(=O)Cn2ccn(-c3ccc(F)c(F)c3)c(=O)c2=O)cc1 nan
CHEMBL1403689 31523 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 2.3 CCOc1ccc(NC(=O)Cn2ccn(-c3ccc(F)c(F)c3)c(=O)c2=O)cc1 nan
654955 31789 5 None -4 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 4.7 CS(=O)(=O)c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N nan
CHEMBL1406204 31789 5 None -4 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 1 6 4.7 CS(=O)(=O)c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N nan
135416200 31791 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
45369539 31791 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
CHEMBL1406220 31791 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.9 CCN(CC)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
16025790 31841 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 4 4.5 CCC(C)NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1406711 31841 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 4 4.5 CCC(C)NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
1257542 31909 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.4 Cc1cccnc1NC(=O)Cn1nc([N+](=O)[O-])cc1C nan
CHEMBL1407331 31909 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 6 1.4 Cc1cccnc1NC(=O)Cn1nc([N+](=O)[O-])cc1C nan
5834534 31965 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(Cl)cc2)c(C)c1 nan
CHEMBL1407665 31965 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 5 5.2 CCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(Cl)cc2)c(C)c1 nan
1509257 31986 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 2 1 5 3.5 CCN1CCc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2C1 nan
CHEMBL1407777 31986 12 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 2 1 5 3.5 CCN1CCc2nc3sc(C(=O)N4CCc5ccccc5C4)c(N)c3cc2C1 nan
981045 32178 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 0 9 -0.1 CCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1409260 32178 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 0 9 -0.1 CCn1c(SCCN2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C nan
2649456 32287 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 2 0 5 2.7 O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1410109 32287 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 2 0 5 2.7 O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2cc(Br)ccc2n1 nan
1191742 32310 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 4.3 O=C(O)CSc1ncnc2scc(-c3ccc(Br)cc3)c12 nan
CHEMBL1410306 32310 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 4.3 O=C(O)CSc1ncnc2scc(-c3ccc(Br)cc3)c12 nan
15990415 32524 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 5 5.5 COc1ccc(Cl)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1412135 32524 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 1 5 5.5 COc1ccc(Cl)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
3151320 32558 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.4 N=c1c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1412407 32558 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.4 N=c1c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
1484210 32563 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 0 5 3.6 CCSc1nnc(-c2ccccc2SC)o1 nan
CHEMBL1412417 32563 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 4 0 5 3.6 CCSc1nnc(-c2ccccc2SC)o1 nan
4433827 33069 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 2.8 CSc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CN(C)CC3 nan
CHEMBL1416667 33069 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 2.8 CSc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CN(C)CC3 nan
3245881 33615 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 9 2.6 COc1cc2nc(S)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
CHEMBL1421316 33615 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 9 2.6 COc1cc2nc(S)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
5102370 33911 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 9 1 5 1.7 CCN(CC)S(=O)(=O)c1cccc(C(=O)NCCCn2ccnc2)c1 nan
CHEMBL1423739 33911 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 9 1 5 1.7 CCN(CC)S(=O)(=O)c1cccc(C(=O)NCCCn2ccnc2)c1 nan
4872167 34138 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 7 5.2 CCCCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1425797 34138 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 7 5.2 CCCCCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
2968003 34193 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 5 3.3 COc1ccc(-c2cc3ccc(OC(C)C(=O)O)cc3oc2=O)cc1 nan
CHEMBL1426170 34193 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 5 3.3 COc1ccc(-c2cc3ccc(OC(C)C(=O)O)cc3oc2=O)cc1 nan
5933014 34805 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 10 2 6 2.7 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccccc2)cc1 nan
CHEMBL1431128 34805 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 10 2 6 2.7 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccccc2)cc1 nan
2365417 34826 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 1 6 5.2 Cc1ccc2nc(-c3ccc(NC(=O)COC(=O)c4cncc(Br)c4)cc3)sc2c1 nan
CHEMBL1431340 34826 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 5 1 6 5.2 Cc1ccc2nc(-c3ccc(NC(=O)COC(=O)c4cncc(Br)c4)cc3)sc2c1 nan
2317063 35021 7 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 2 5 5.6 CCCCOc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2)cc1 nan
CHEMBL1433074 35021 7 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 2 5 5.6 CCCCOc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2)cc1 nan
16016637 35075 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 1 5 5.0 CCOc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-n2cccc2)cc1 nan
CHEMBL1433449 35075 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 1 5 5.0 CCOc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2-n2cccc2)cc1 nan
16012551 35122 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 5 5.5 CCOc1ccc(-c2cc(NC(=O)c3cccc(Cl)c3)c(C(=O)OC)s2)cc1 nan
CHEMBL1434218 35122 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 5 5.5 CCOc1ccc(-c2cc(NC(=O)c3cccc(Cl)c3)c(C(=O)OC)s2)cc1 nan
16033555 35171 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 0 4 4.8 Cc1nc(Oc2ccccc2C)c2oc3ccccc3c2n1 nan
CHEMBL1434916 35171 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 0 4 4.8 Cc1nc(Oc2ccccc2C)c2oc3ccccc3c2n1 nan
16025666 35294 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 7 4.3 Cc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1 nan
CHEMBL1436433 35294 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 7 4.3 Cc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1 nan
16015798 35315 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 4 5.6 Cc1ccc(-c2nc3cc(Cl)ccc3o2)cc1NC(=O)COc1ccc(F)cc1 nan
CHEMBL1436774 35315 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 4 5.6 Cc1ccc(-c2nc3cc(Cl)ccc3o2)cc1NC(=O)COc1ccc(F)cc1 nan
16018841 35364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 4 5.0 Cc1c(C(=O)Nc2ccc(F)cc2F)oc2ccc3c(c12)C(=O)CC(C)(C)O3 nan
CHEMBL1437356 35364 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 2 1 4 5.0 Cc1c(C(=O)Nc2ccc(F)cc2F)oc2ccc3c(c12)C(=O)CC(C)(C)O3 nan
1004026 35394 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 6 5.2 CCOc1ccccc1NC(=O)c1sc2nc(-c3ccc(OC)cc3)ccc2c1N nan
CHEMBL1437726 35394 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 6 5.2 CCOc1ccccc1NC(=O)c1sc2nc(-c3ccc(OC)cc3)ccc2c1N nan
16022287 35495 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 1 4 3.3 CCCCNC(=O)c1cccc(-n2c(C)nc3cccnc32)c1 nan
CHEMBL1438563 35495 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 1 4 3.3 CCCCNC(=O)c1cccc(-n2c(C)nc3cccnc32)c1 nan
5809896 35556 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 4.0 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1439160 35556 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 4.0 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
15988173 35576 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 4 2.9 Cc1ccc(CNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
CHEMBL1439335 35576 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 4 2.9 Cc1ccc(CNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
1454908 36067 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 1 4 3.5 Sc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1443793 36067 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 1 4 3.5 Sc1nc(COc2ccccc2)nc2ccccc12 nan
1234247 36310 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 5 2.7 Cc1nnc(S)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1446078 36310 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 1 1 5 2.7 Cc1nnc(S)c2nn(-c3ccccc3)c(C)c12 nan
16026772 36367 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 1.8 Cc1ccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
CHEMBL1446594 36367 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 1.8 Cc1ccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
2957415 36735 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 2.5 CC(=O)c1nc(N2C(=O)C3CC=C(C)CC3C2=O)sc1C nan
CHEMBL1449518 36735 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 2.5 CC(=O)c1nc(N2C(=O)C3CC=C(C)CC3C2=O)sc1C nan
2334194 36786 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 8 3.6 CCOC(=O)c1c(NS(=O)(=O)c2ccccc2)n(CCCOC)c2nc3ccccc3nc12 nan
CHEMBL1449923 36786 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 1 8 3.6 CCOC(=O)c1c(NS(=O)(=O)c2ccccc2)n(CCCOC)c2nc3ccccc3nc12 nan
4977513 36823 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(OC(C)C)cc2)no1 nan
CHEMBL1450219 36823 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 5.3 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2ccc(OC(C)C)cc2)no1 nan
2945668 36998 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 1.8 CCc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
CHEMBL1451692 36998 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 1.8 CCc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 nan
24792337 37076 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 7 1.6 Cc1cc2nnc(SCC(=O)NC3CCCCC3)n2c(N)n1 nan
CHEMBL1452223 37076 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 7 1.6 Cc1cc2nnc(SCC(=O)NC3CCCCC3)n2c(N)n1 nan
15988498 37116 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 11 2 9 2.9 CCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
CHEMBL1452564 37116 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 11 2 9 2.9 CCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
2298970 37122 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3ccncc3)cc2)c1C nan
CHEMBL1452655 37122 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C/C(=O)c3ccncc3)cc2)c1C nan
24790128 37414 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 5 3.2 COc1ccc(-c2[nH]ncc2CN2CCN(C(=O)c3cccs3)CC2)c(F)c1 nan
CHEMBL1454939 37414 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 5 3.2 COc1ccc(-c2[nH]ncc2CN2CCN(C(=O)c3cccs3)CC2)c(F)c1 nan
16030361 37474 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 9 1 5 4.7 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)c1 nan
CHEMBL1455531 37474 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 9 1 5 4.7 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)c1 nan
16025668 37673 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 8 4.6 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1Cl nan
CHEMBL1457411 37673 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 8 4.6 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4ccc(C)c(C)c4)n3)c2C)cc1Cl nan
1355891 37789 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 11 1 7 3.2 COc1ccc(OC)c(N(CC(=O)NCc2ccccc2)S(=O)(=O)c2ccc(OC)c(OC)c2)c1 nan
CHEMBL1458278 37789 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 11 1 7 3.2 COc1ccc(OC)c(N(CC(=O)NCc2ccccc2)S(=O)(=O)c2ccc(OC)c(OC)c2)c1 nan
2949787 37887 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.4 COc1ccccc1C1C(C(=O)c2ccco2)=C(O)C(=O)N1c1cc(C)on1 nan
CHEMBL1459163 37887 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.4 COc1ccccc1C1C(C(=O)c2ccco2)=C(O)C(=O)N1c1cc(C)on1 nan
1445336 37891 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 8 3.9 COc1ccccc1N1CCN(C(=O)CSc2ncnc3c2cnn3-c2ccc(C)c(C)c2)CC1 nan
CHEMBL1459184 37891 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 8 3.9 COc1ccccc1N1CCN(C(=O)CSc2ncnc3c2cnn3-c2ccc(C)c(C)c2)CC1 nan
6033330 38031 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 11 1 8 3.9 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1460387 38031 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 11 1 8 3.9 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
5160710 38071 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 2 2 4.5 CCCOc1ccc(NC(=O)c2cc3cc(C)ccc3[nH]2)cc1 nan
CHEMBL1460665 38071 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 5 2 2 4.5 CCCOc1ccc(NC(=O)c2cc3cc(C)ccc3[nH]2)cc1 nan
3502512 38157 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 8 1.0 N#Cc1c(N2CCOCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
CHEMBL1461443 38157 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 8 1.0 N#Cc1c(N2CCOCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
2810150 38240 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 4.1 Cc1csc2c(=O)sc(NC(=O)c3ccc(F)cc3Cl)nc12 nan
CHEMBL1462227 38240 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 4.1 Cc1csc2c(=O)sc(NC(=O)c3ccc(F)cc3Cl)nc12 nan
4524521 38275 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 7 0.2 Cn1c(C(=O)NCCN2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1462442 38275 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 7 0.2 Cn1c(C(=O)NCCN2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
1491130 38332 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 5 1 5 3.3 O=C(O)COc1ccc(-c2nccc(-c3cccs3)n2)cc1 nan
CHEMBL1462936 38332 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 5 1 5 3.3 O=C(O)COc1ccc(-c2nccc(-c3cccs3)n2)cc1 nan
135464100 38445 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 2 6 3.3 N#Cc1c(O)nc(SCC(=O)NC2CCCCC2)nc1-c1ccccc1 nan
CHEMBL1463888 38445 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 2 6 3.3 N#Cc1c(O)nc(SCC(=O)NC2CCCCC2)nc1-c1ccccc1 nan
2808819 38696 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 4.1 Cc1csc2ncnc(NC3CCN(Cc4ccccc4)CC3)c12 nan
CHEMBL1465720 38696 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 4.1 Cc1csc2ncnc(NC3CCN(Cc4ccccc4)CC3)c12 nan
1100812 38737 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 6 4.4 CCOC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
CHEMBL1466098 38737 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 6 4.4 CCOC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
665758 38757 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 7 4.3 COc1cc(OC)cc(-c2nc(-c3cc4cc(C)ccc4nc3OC)no2)c1 nan
CHEMBL1466279 38757 8 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 7 4.3 COc1cc(OC)cc(-c2nc(-c3cc4cc(C)ccc4nc3OC)no2)c1 nan
20953708 39059 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.2 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)nc(C)n3n2)cc1 nan
CHEMBL1468743 39059 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.2 COc1ccc(-c2cc3c(=O)n(CC(=O)Nc4cccc(Cl)c4)nc(C)n3n2)cc1 nan
2913184 39156 15 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 7 3.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
CHEMBL1469528 39156 15 None -3 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 7 3.4 Cc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
1226649 39180 14 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 2 4 4.1 CC(=O)NC(=S)Nc1ccc(-c2nc3ccc(C)cc3s2)cc1 nan
CHEMBL1469733 39180 14 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 2 4 4.1 CC(=O)NC(=S)Nc1ccc(-c2nc3ccc(C)cc3s2)cc1 nan
794237 39307 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 5 3.5 COc1ccc(C(=O)Nc2nnc(-c3ccccc3)s2)cc1 nan
CHEMBL1470825 39307 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 5 3.5 COc1ccc(C(=O)Nc2nnc(-c3ccccc3)s2)cc1 nan
1025062 39491 9 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 7 1 5 5.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c(C#N)c(C)c1CC(=O)c1ccc(Br)cc1 nan
CHEMBL1472426 39491 9 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 7 1 5 5.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c(C#N)c(C)c1CC(=O)c1ccc(Br)cc1 nan
16025800 39613 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 5 3.7 COCCCNC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1474073 39613 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 5 3.7 COCCCNC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
16017955 39630 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 5 3.3 Cc1ccc(NC(=O)c2nc(-c3ccncc3)no2)c(Cl)c1 nan
CHEMBL1474407 39630 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 5 3.3 Cc1ccc(NC(=O)c2nc(-c3ccncc3)no2)c(Cl)c1 nan
923699 39812 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 1 4 4.8 Cc1cc(C)cc(C(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c1 nan
CHEMBL1476840 39812 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 3 1 4 4.8 Cc1cc(C)cc(C(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c1 nan
16030273 39853 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccccc3F)CC2)cc1 nan
CHEMBL1477298 39853 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 6 0 5 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCN(c3ccccc3F)CC2)cc1 nan
3492613 40101 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 4.6 COc1ccc(-n2cc(-c3ccc(Br)cc3)nc2S)cc1 nan
CHEMBL1479477 40101 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 4.6 COc1ccc(-n2cc(-c3ccc(Br)cc3)nc2S)cc1 nan
1077503 40129 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 7 1.9 CCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1479731 40129 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 2 7 1.9 CCCn1c(=N)c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc21 nan
2059287 40410 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 5 3.5 CCCCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1482087 40410 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 5 3.5 CCCCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
2490618 40429 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 9 0.0 CCc1ccc(OCC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1 nan
CHEMBL1482290 40429 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 7 1 9 0.0 CCc1ccc(OCC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1 nan
16020212 40880 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 7 2 8 3.8 Cc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
CHEMBL1486218 40880 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 7 2 8 3.8 Cc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
5835099 41345 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 1 6 5.0 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1C nan
CHEMBL1489865 41345 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 8 1 6 5.0 CCCOc1ccc(C(=O)C2=C(O)C(=O)N(c3ccccn3)C2c2ccc(OC)cc2)cc1C nan
24791694 41442 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 4 4.0 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cccnc4)C3)ccc2c1 nan
CHEMBL1490547 41442 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 4 4.0 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cccnc4)C3)ccc2c1 nan
135438626 41708 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 3 9 0.8 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nc(N)cc(O)n1 nan
CHEMBL1492401 41708 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 3 9 0.8 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nc(N)cc(O)n1 nan
16018070 41745 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 4 3.5 O=C(CCCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1 nan
CHEMBL1492679 41745 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 4 3.5 O=C(CCCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1 nan
1327115 41836 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 1 5 4.8 COc1cccc(-c2cc3c(=O)n(-c4ccccc4)c(=S)[nH]c3s2)c1 nan
CHEMBL1493481 41836 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 3 1 5 4.8 COc1cccc(-c2cc3c(=O)n(-c4ccccc4)c(=S)[nH]c3s2)c1 nan
3034554 41944 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 7 1.5 Cn1c(=S)c2nc(SCCN3CCCC3)[nH]c2n(C)c1=O nan
CHEMBL1494615 41944 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 7 1.5 Cn1c(=S)c2nc(SCCN3CCCC3)[nH]c2n(C)c1=O nan
976285 42341 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 0 5 2.1 Cc1csc2nc(=O)c(-c3ccccc3)nn12 nan
CHEMBL1498297 42341 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 0 5 2.1 Cc1csc2nc(=O)c(-c3ccccc3)nn12 nan
3127165 42611 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 0.5 CC(C(O)c1ccccc1)N(C)CCn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1500612 42611 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 8 0.5 CC(C(O)c1ccccc1)N(C)CCn1cnc2c1c(=O)n(C)c(=O)n2C nan
135413586 42691 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 2 10 3.0 CCOC(=O)Cc1csc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)n1 nan
CHEMBL1501394 42691 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 2 10 3.0 CCOC(=O)Cc1csc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)n1 nan
5903312 42830 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 8 0.1 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2ccccn2c1=O nan
CHEMBL1502541 42830 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 8 0.1 COCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2ccccn2c1=O nan
790333 43264 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1cc(S)c2cccc(C)c2n1 nan
CHEMBL1506363 43264 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1cc(S)c2cccc(C)c2n1 nan
2146623 43596 17 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 4 5.0 CC(=O)c1ccc(NC(=O)c2ccc(CSc3ccccc3)o2)cc1 nan
CHEMBL1509267 43596 17 None 1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 4 5.0 CC(=O)c1ccc(NC(=O)c2ccc(CSc3ccccc3)o2)cc1 nan
4617873 43912 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 2 3 4.4 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccccc3Br)cc2)cc1 nan
CHEMBL1512241 43912 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 2 3 4.4 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccccc3Br)cc2)cc1 nan
7877577 44012 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 7 1.4 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1513627 44012 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 7 1.4 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2ccsc2n1 nan
7598873 44050 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 3 3.9 CCc1ccccc1NC(=O)c1cccn(Cc2ccccc2F)c1=O nan
CHEMBL1514321 44050 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 3 3.9 CCc1ccccc1NC(=O)c1cccn(Cc2ccccc2F)c1=O nan
16030561 44063 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 6 0 5 5.5 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1514538 44063 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 6 0 5 5.5 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCN(c2ccccc2F)CC1 nan
16009347 44066 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cc(C)cc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
CHEMBL1514567 44066 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cc(C)cc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
16018206 44076 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1cc(NC(=O)c2oc3c(c2C)-c2nn(Cc4cccc(Cl)c4)cc2CC3)cc(OC)c1 nan
CHEMBL1514692 44076 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1cc(NC(=O)c2oc3c(c2C)-c2nn(Cc4cccc(Cl)c4)cc2CC3)cc(OC)c1 nan
3207800 44325 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2nc(SCC(=O)Nc3cc(C)on3)c(C#N)cc2c1 nan
CHEMBL1517790 44325 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2nc(SCC(=O)Nc3cc(C)on3)c(C#N)cc2c1 nan
2091511 44377 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 0 8 2.5 Cc1ccc2nc(CSc3nnc(-c4ccncc4)n3C)cc(=O)n2c1 nan
CHEMBL1518274 44377 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 0 8 2.5 Cc1ccc2nc(CSc3nnc(-c4ccncc4)n3C)cc(=O)n2c1 nan
24818303 44379 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 1 3 4.4 CN(C)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
CHEMBL1518303 44379 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 1 3 4.4 CN(C)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
5151092 44382 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 1 2 3.2 CNC(=O)c1c2c(nc3ccc(Br)cc13)CCCC2 nan
CHEMBL1518360 44382 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 1 1 2 3.2 CNC(=O)c1c2c(nc3ccc(Br)cc13)CCCC2 nan
16019804 44546 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 9 1 8 1.6 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCCOC)nnc12 nan
CHEMBL1519737 44546 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 9 1 8 1.6 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCCOC)nnc12 nan
4917226 44612 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 2 4 5.8 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(OC2CCCC2)cc1 nan
CHEMBL1520355 44612 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 2 4 5.8 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(OC2CCCC2)cc1 nan
24677542 44689 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 8 4 5 3.0 CCCCCNC(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(O)nc3c2)cc1 nan
CHEMBL1520946 44689 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 8 4 5 3.0 CCCCCNC(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(O)nc3c2)cc1 nan
902803 44855 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 5 1 2 4.5 O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1 nan
CHEMBL1522424 44855 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 5 1 2 4.5 O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1 nan
15988611 45062 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 8 3.9 CC(=O)c1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1524392 45062 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 8 3.9 CC(=O)c1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1 nan
3239863 45222 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 0 8 2.4 CCOC(=O)CC(=O)CSc1ccc2nnc(-c3ccccc3)n2n1 nan
CHEMBL1525909 45222 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 7 0 8 2.4 CCOC(=O)CC(=O)CSc1ccc2nnc(-c3ccccc3)n2n1 nan
2930800 45302 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 7 2.5 COC(=O)c1sc(NC(=O)C2CCCCC2C(=O)O)c(C(=O)OC)c1C nan
CHEMBL1526492 45302 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 7 2.5 COC(=O)c1sc(NC(=O)C2CCCCC2C(=O)O)c(C(=O)OC)c1C nan
2349018 45484 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 2 1 4 3.4 CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1528175 45484 22 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 2 1 4 3.4 CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
1355435 45498 11 None -22 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 3.3 Cc1cn(S(=O)(=O)c2ccc(Br)c3ccccc23)cn1 nan
CHEMBL1528299 45498 11 None -22 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 3.3 Cc1cn(S(=O)(=O)c2ccc(Br)c3ccccc23)cn1 nan
5073065 45596 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 6 -0.6 O=C(Cn1cnc2ccccc2c1=O)NCC(=O)N1CCOCC1 nan
CHEMBL1529152 45596 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 6 -0.6 O=C(Cn1cnc2ccccc2c1=O)NCC(=O)N1CCOCC1 nan
3240741 45689 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 9 1 8 4.6 COc1ccc(CC(=O)Nc2ccc(-c3noc(-c4cc(OC)c(OC)c(OC)c4)n3)cc2)cc1 nan
CHEMBL1529936 45689 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 9 1 8 4.6 COc1ccc(CC(=O)Nc2ccc(-c3noc(-c4cc(OC)c(OC)c(OC)c4)n3)cc2)cc1 nan
3212225 45714 2 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1530244 45714 2 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
16024952 45716 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.0 CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)c1 nan
CHEMBL1530263 45716 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.0 CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)c1 nan
16017576 45727 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 7 2.2 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1530393 45727 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 7 2.2 CN(Cc1ccco1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
4907979 45736 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 6 3.0 OCCCNc1ncnc2sc3c(c12)CCN(Cc1ccccc1)C3 nan
CHEMBL1530465 45736 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 6 3.0 OCCCNc1ncnc2sc3c(c12)CCN(Cc1ccccc1)C3 nan
1161207 45817 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 8 2 7 3.1 COc1ccccc1OCC(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1531098 45817 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 8 2 7 3.1 COc1ccccc1OCC(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
1355556 45881 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 1 3 3.8 O=S(=O)(Nc1cccnc1)c1ccc(Br)c2ccccc12 nan
CHEMBL1531651 45881 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 1 3 3.8 O=S(=O)(Nc1cccnc1)c1ccc(Br)c2ccccc12 nan
16025786 46102 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 4 5.3 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccc(F)cc3)CC2)s1 nan
CHEMBL1533608 46102 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 4 5.3 Cc1cc2ccccc2n1-c1ccc(C(=O)N2CCC(C(=O)NCc3ccc(F)cc3)CC2)s1 nan
3151323 46188 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.3 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1534442 46188 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 2 7 2.3 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CC4CCCO4)c3nc12 nan
3238163 46429 7 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 8 0.6 Cc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
CHEMBL1536880 46429 7 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 8 0.6 Cc1ccc(-n2nnc3c(=O)n(CC(=O)NCC4CCCO4)cnc32)cc1 nan
2989967 46512 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 3.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)no1 nan
CHEMBL1537625 46512 19 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 3.5 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)no1 nan
767265 46767 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 5 3.5 Sc1nnc(-c2ccco2)n1-c1ccc(Cl)cc1 nan
CHEMBL1539766 46767 34 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 5 3.5 Sc1nnc(-c2ccco2)n1-c1ccc(Cl)cc1 nan
891408 47203 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 4 0 6 1.7 O=C(OCc1cccc([N+](=O)[O-])c1)c1cnccn1 nan
CHEMBL1543385 47203 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 4 0 6 1.7 O=C(OCc1cccc([N+](=O)[O-])c1)c1cnccn1 nan
4634206 47295 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 10 -0.9 CCOc1ccccc1OCC(=O)NNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1544116 47295 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 10 -0.9 CCOc1ccccc1OCC(=O)NNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1487485 47299 21 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 3 3.1 Cc1ccc(-n2ncc(Br)c(Br)c2=O)cc1 nan
CHEMBL1544131 47299 21 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 3 3.1 Cc1ccc(-n2ncc(Br)c(Br)c2=O)cc1 nan
1867273 47385 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
CHEMBL1544770 47385 18 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 7 1.8 Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)NCCO nan
3781367 47437 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 2 8 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
CHEMBL1545158 47437 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 2 8 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CC(C)(C)OC4)cc1 nan
28358049 47684 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
5398465 47684 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
CHEMBL1547311 47684 21 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 4 3.3 CCN(CC)Cc1c(O)c(Cl)cc2c(C)cc(=O)oc12 nan
7080334 47695 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 3.6 Cc1c(-c2cccc(NC(=O)c3ccco3)c2)nc2ncccn12 nan
CHEMBL1547414 47695 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 3.6 Cc1c(-c2cccc(NC(=O)c3ccco3)c2)nc2ncccn12 nan
1476696 47722 24 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 0 4 4.8 CSc1cc(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)c1C#N nan
CHEMBL1547693 47722 24 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 0 4 4.8 CSc1cc(-c2ccc(Cl)cc2)n(Cc2ccccc2)c(=O)c1C#N nan
3830390 47816 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 2 8 -1.2 CN(N)N=Nc1nc2c(=O)n(C)c(=O)n(C)c2[nH]1 nan
CHEMBL1548599 47816 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 2 2 8 -1.2 CN(N)N=Nc1nc2c(=O)n(C)c(=O)n(C)c2[nH]1 nan
20885691 48117 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 7 1 6 1.9 CCc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1551091 48117 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 7 1 6 1.9 CCc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
2053967 48136 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 0 5 4.3 CCCCN(CCCC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
CHEMBL1551348 48136 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 0 5 4.3 CCCCN(CCCC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 nan
7151074 48193 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.1 O=C(CSc1nccn1Cc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2 nan
CHEMBL1552167 48193 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 4.1 O=C(CSc1nccn1Cc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2 nan
16025798 48385 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 4 5.0 O=C(NCc1ccc(F)cc1)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
CHEMBL1554965 48385 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 4 5.0 O=C(NCc1ccc(F)cc1)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1 nan
16019077 48443 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1555692 48443 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2913061 48549 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 6 3.8 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1556761 48549 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 6 3.8 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
4158621 48595 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(F)cc1Cl nan
CHEMBL1557087 48595 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(F)cc1Cl nan
2448835 48982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 9 1.4 CCCn1c(N)c(C(=O)CSc2nc3cc(Cl)c[nH]c-3n2)c(=O)n(C)c1=O nan
CHEMBL1560544 48982 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 9 1.4 CCCn1c(N)c(C(=O)CSc2nc3cc(Cl)c[nH]c-3n2)c(=O)n(C)c1=O nan
20921616 49029 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 2.6 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccccc3)s2)cc1OC nan
CHEMBL1561011 49029 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 2.6 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccccc3)s2)cc1OC nan
7190686 49204 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccccc1NC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1562578 49204 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccccc1NC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
3152540 49214 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.0 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1)c1ccco1 nan
CHEMBL1562668 49214 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.0 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1)c1ccco1 nan
4367682 49624 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 1 3 2.6 Cc1nc2ccc(Br)cc2c2c1CC(CO)O2 nan
CHEMBL1566103 49624 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 1 1 3 2.6 Cc1nc2ccc(Br)cc2c2c1CC(CO)O2 nan
1569279 49698 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 3.3 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCCN1CCOCC1 nan
CHEMBL1566690 49698 17 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 3.3 CCOC(=O)c1cnc2ccc(Br)cc2c1NCCCN1CCOCC1 nan
7881996 49706 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 1 8 1.2 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1566736 49706 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 1 8 1.2 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
3146574 49772 15 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 8 3.2 COc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1567207 49772 15 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 8 3.2 COc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
1226038 49943 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 3 0 3 5.3 CC(C)c1ccc(-c2cc(C(=O)N3CCOCC3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1568600 49943 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 3 0 3 5.3 CC(C)c1ccc(-c2cc(C(=O)N3CCOCC3)c3cc(Br)ccc3n2)cc1 nan
20904702 50034 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 8 2.1 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1569451 50034 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 8 2.1 CCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
16017333 50086 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 7 1.6 COc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCCC3)s2)c1 nan
CHEMBL1569922 50086 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 7 1.6 COc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCCC3)s2)c1 nan
1840878 50097 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 2 7 1.8 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NC1CCCCC1 nan
CHEMBL1570011 50097 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 2 7 1.8 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NC1CCCCC1 nan
2134950 50214 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3sccc32)c1 nan
CHEMBL1570886 50214 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3sccc32)c1 nan
16017067 50543 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.8 CCC(C(=O)NCc1ccccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1574126 50543 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.8 CCC(C(=O)NCc1ccccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
860331 50651 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc2ccccc2nc1SCC(=O)NC1CCCC1 nan
CHEMBL1575355 50651 2 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc2ccccc2nc1SCC(=O)NC1CCCC1 nan
3771682 50741 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 5 5.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(C(C)C)cc2)n1 nan
CHEMBL1576217 50741 12 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 5 5.4 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2ccc(C(C)C)cc2)n1 nan
20957197 50808 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 9 2.0 COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1576697 50808 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 9 2.0 COc1ccc(NC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
5738492 50997 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 7 1 6 3.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc3c(c2)CC(C)O3)C1c1cccnc1 nan
CHEMBL1578334 50997 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 7 1 6 3.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc3c(c2)CC(C)O3)C1c1cccnc1 nan
2503775 51050 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 1 5 2.3 O=C(CSc1nnc2ccccn12)NCCc1ccc(F)cc1 nan
CHEMBL1578723 51050 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 1 5 2.3 O=C(CSc1nnc2ccccn12)NCCc1ccc(F)cc1 nan
4605879 51072 10 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.3 C=CCSc1nc(O)c2c(n1)OC(N)=C(C#N)C2C(C)C nan
CHEMBL1578918 51072 10 None -3 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.3 C=CCSc1nc(O)c2c(n1)OC(N)=C(C#N)C2C(C)C nan
2366506 51242 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc2c(c1)OCCO2 nan
CHEMBL1580473 51242 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc2c(c1)OCCO2 nan
135433335 51456 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
1426566 51456 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
CHEMBL1582229 51456 16 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.7 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccn1 nan
5310097 51477 1 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.7 Cc1ccc(-c2nnc3ccc(SC(C)C(=O)O)nn23)cc1 nan
CHEMBL1582406 51477 1 None -4 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.7 Cc1ccc(-c2nnc3ccc(SC(C)C(=O)O)nn23)cc1 nan
4099137 51544 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccccc1Cl nan
CHEMBL1583052 51544 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccccc1Cl nan
661828 52122 14 None -14 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(OC)c(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1587683 52122 14 None -14 3 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(OC)c(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2004544 52257 16 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1F nan
CHEMBL1588950 52257 16 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1F nan
1003437 52463 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 3 2 5 5.3 Cc1cc(F)ccc1NC(=O)c1sc2nc(-c3cccs3)ccc2c1N nan
CHEMBL1591017 52463 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 3 2 5 5.3 Cc1cc(F)ccc1NC(=O)c1sc2nc(-c3cccs3)ccc2c1N nan
16019053 52472 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 6 4.0 CCCSCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1591213 52472 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 6 4.0 CCCSCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16015858 52476 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.3 O=C(COc1ccccc1Cl)Nc1ccc2oc(-c3ccccc3F)nc2c1 nan
CHEMBL1591250 52476 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.3 O=C(COc1ccccc1Cl)Nc1ccc2oc(-c3ccccc3F)nc2c1 nan
16027414 52535 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 3.6 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1ccccc1 nan
CHEMBL1591957 52535 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 3.6 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1ccccc1 nan
16029938 52581 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 6 2.8 Cc1ccn2c(=O)c(NC(=O)c3cccc([N+](=O)[O-])c3C)c(C)nc2c1 nan
CHEMBL1592574 52581 10 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 6 2.8 Cc1ccn2c(=O)c(NC(=O)c3cccc([N+](=O)[O-])c3C)c(C)nc2c1 nan
15990931 52601 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 2 3 6.1 CC(C)c1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1592841 52601 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 2 3 6.1 CC(C)c1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)cc1 nan
801483 52718 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 2 4 5.2 Oc1cccc(-c2nc(-c3cccs3)c(-c3cccs3)[nH]2)c1 nan
CHEMBL1594404 52718 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 2 4 5.2 Oc1cccc(-c2nc(-c3cccs3)c(-c3cccs3)[nH]2)c1 nan
7189836 52912 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 7 3.3 COc1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)c(OC)c1 nan
CHEMBL1596046 52912 11 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 7 3.3 COc1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)c(OC)c1 nan
4137685 52958 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 5.8 COc1cccc(C(=O)c2sc3nc(-c4ccccc4)cc(C(F)(F)F)c3c2N)c1 nan
CHEMBL1596431 52958 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 5.8 COc1cccc(C(=O)c2sc3nc(-c4ccccc4)cc(C(F)(F)F)c3c2N)c1 nan
3916490 53081 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.7 CCN(CC)S(=O)(=O)c1cccc(NC(=O)COc2ncnc3sccc23)c1 nan
CHEMBL1597614 53081 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.7 CCN(CC)S(=O)(=O)c1cccc(NC(=O)COc2ncnc3sccc23)c1 nan
16195124 53276 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 2.4 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC)cc2)C12C(=O)N(C)c1ccccc12 nan
CHEMBL1599313 53276 8 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 2.4 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC)cc2)C12C(=O)N(C)c1ccccc12 nan
135419123 53417 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 1 3 5.5 Cc1ccc(C2=Nc3ccccc3N=C(c3ccc(F)cc3)C2)c(O)c1 nan
CHEMBL1600651 53417 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 1 3 5.5 Cc1ccc(C2=Nc3ccccc3N=C(c3ccc(F)cc3)C2)c(O)c1 nan
16018987 53428 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 3.7 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1OC nan
CHEMBL1600729 53428 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 3.7 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1OC nan
16009272 53677 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 3.2 COc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 nan
CHEMBL1603189 53677 1 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 6 3.2 COc1ccc(CNC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 nan
2816428 53795 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 2 0 5 2.8 C=CCn1c2ccccc2c2nn(C)c(=S)nc21 nan
CHEMBL1604034 53795 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 256 2 0 5 2.8 C=CCn1c2ccccc2c2nn(C)c(=S)nc21 nan
3765596 53968 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1605561 53968 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 4.5 COc1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
4524651 54459 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 5 2.5 CC1CCCCC1NC(=O)c1cc2c(=O)n3ccccc3nc2n1C nan
CHEMBL1609461 54459 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 1 5 2.5 CC1CCCCC1NC(=O)c1cc2c(=O)n3ccccc3nc2n1C nan
901441 54470 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 1 1 3 3.3 Cc1cc2sc(C(=O)O)c(C)c2s1 nan
CHEMBL1609556 54470 10 None -1 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 212 1 1 3 3.3 Cc1cc2sc(C(=O)O)c(C)c2s1 nan
6498451 54551 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 9 1.8 COc1cc2c3nc4n(c(=O)c3n(CC(=O)NCC3CCCO3)c2cc1OC)CCS4 nan
CHEMBL1610295 54551 4 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 9 1.8 COc1cc2c3nc4n(c(=O)c3n(CC(=O)NCC3CCCO3)c2cc1OC)CCS4 nan
16022543 54609 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 2 8 4.1 CCN(CC)CCNC(=O)c1ccc2c(=O)n3nc(Nc4cccc(Cl)c4C)sc3nc2c1 nan
CHEMBL1610849 54609 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 8 2 8 4.1 CCN(CC)CCNC(=O)c1ccc2c(=O)n3nc(Nc4cccc(Cl)c4C)sc3nc2c1 nan
16013346 54732 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 1 5 4.2 Cc1cc2oc(C(=O)Nc3ccc(S(=O)(=O)N4CCCCCC4)cc3)cc(=O)c2cc1C nan
CHEMBL1611855 54732 9 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 1 5 4.2 Cc1cc2oc(C(=O)Nc3ccc(S(=O)(=O)N4CCCCCC4)cc3)cc(=O)c2cc1C nan
2816611 54796 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 2 7 2.8 CCOC(=O)N1CCc2c(sc3nc(S)nc(S)c23)C1 nan
CHEMBL1612443 54796 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 2 7 2.8 CCOC(=O)N1CCc2c(sc3nc(S)nc(S)c23)C1 nan
2967714 54830 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 4.5 COc1ccc(C(=O)Nc2ccc(C(=O)Nc3cccc(C)c3)cc2)cc1 nan
CHEMBL1612735 54830 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 3 4.5 COc1ccc(C(=O)Nc2ccc(C(=O)Nc3cccc(C)c3)cc2)cc1 nan
16019073 54868 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 1 6 4.1 CCOc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1613149 54868 6 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 1 6 4.1 CCOc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
4723782 55271 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
CHEMBL1342613 55271 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
CHEMBL1618192 55271 15 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 3 4.4 Brc1ccc(-c2ccc(CNCc3ccccn3)o2)cc1 nan
20279 55357 98 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
CHEMBL1619 55357 98 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 2 3 8 -0.3 Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1 nan
1712157 55583 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
CHEMBL1455081 55583 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
CHEMBL1620984 55583 11 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 6 1.6 O=C(NCCOC(=O)c1ccc([N+](=O)[O-])cc1)c1cccnc1 nan
616262 55721 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
CHEMBL1505364 55721 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
CHEMBL1622190 55721 13 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 3 1 5 2.8 CC(=O)c1sc(Nc2ccccn2)nc1C nan
1554378 56156 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1577432 56156 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1625977 56156 14 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 6 1 5 3.7 CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12 nan
3098134 72088 5 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.6 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\c1cccc(O)c1 nan
CHEMBL1977502 72088 5 None -2 2 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 4 1 7 4.6 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\c1cccc(O)c1 nan
9687993 107803 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 6 2.7 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1cccc([N+](=O)[O-])c1 nan
CHEMBL3191955 107803 3 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 6 2.7 C/C(=N\NC(=O)c1c(C)nc2ccccn12)c1cccc([N+](=O)[O-])c1 nan
3095208 107992 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 4 2.6 O=C1C=C(Nc2ccccc2C(=O)O)c2ccccc2C1=O nan
CHEMBL3194086 107992 5 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 4 2.6 O=C1C=C(Nc2ccccc2C(=O)O)c2ccccc2C1=O nan
9638310 108172 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 6 1.5 C/C(=N\NC(=O)c1cnccn1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3196238 108172 7 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 6 1.5 C/C(=N\NC(=O)c1cnccn1)c1ccc([N+](=O)[O-])cc1 nan
102175 141272 72 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 4 9 -1.5 CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O nan
CHEMBL383144 141272 72 None - 1 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 3 4 9 -1.5 CNc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O nan
6083 204815 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
CHEMBL1315633 204815 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
CHEMBL752 204815 95 None -44 7 Human 4.7 pPotency = 4.7 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O nan
4324298 28627 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 0.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccc(=O)n(C)n2)c1 nan
CHEMBL1377104 28627 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 0.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccc(=O)n(C)n2)c1 nan
15988970 44057 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 3 6.2 CCc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
CHEMBL1514445 44057 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 3 6.2 CCc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
15988960 48524 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 3 5.5 CC(C)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1556439 48524 7 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 3 5.5 CC(C)CCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
3119935 52705 19 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 2 6 3.7 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
CHEMBL1594298 52705 19 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 2 6 3.7 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 nan
735254 10458 80 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 178 1 1 3 2.4 S=c1[nH]nc(-c2ccccc2)o1 nan
CHEMBL1164316 10458 80 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 178 1 1 3 2.4 S=c1[nH]nc(-c2ccccc2)o1 nan
5904441 11351 14 None -6 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 3.1 N#C/C(=C\c1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 nan
CHEMBL117966 11351 14 None -6 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 3.1 N#C/C(=C\c1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 nan
1004068 18362 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)cc1 nan
CHEMBL1271076 18362 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 5 5.1 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(Cl)cc4)sc3n2)cc1 nan
3626929 19542 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.7 CC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCCCC3)c3ccccc23)cc1 nan
CHEMBL1299573 19542 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.7 CC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCCCC3)c3ccccc23)cc1 nan
5852174 19632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 4.0 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1300425 19632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 4.0 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
15988009 19711 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
CHEMBL1300978 19711 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 9 1 9 2.3 COc1ccc(OC)c(CCNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)c1 nan
3688325 19802 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 6 2.9 CC(=O)Nc1cccc(C2=CC(c3ccco3)n3ncnc3N2)c1 nan
CHEMBL1301688 19802 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 2 6 2.9 CC(=O)Nc1cccc(C2=CC(c3ccco3)n3ncnc3N2)c1 nan
20957233 19842 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 2.3 CC(CNC(=O)CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)c1ccccc1 nan
CHEMBL1302111 19842 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 2.3 CC(CNC(=O)CCc1nnc2ccc(N3CCC4(CC3)OCCO4)nn12)c1ccccc1 nan
17584169 19955 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 5 3.3 O=C(COc1cc2oc(=O)c3c(c2cc1Cl)CCC3)Nc1ccccn1 nan
CHEMBL1302915 19955 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 5 3.3 O=C(COc1cc2oc(=O)c3c(c2cc1Cl)CCC3)Nc1ccccn1 nan
852288 20118 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 5 0.9 Cn1c(C(=O)O)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1304220 20118 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 5 0.9 Cn1c(C(=O)O)cc2c(=O)n3ccccc3nc21 nan
4145244 20127 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 0.6 Cn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1304271 20127 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 0.6 Cn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 nan
2429052 20227 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 5 5.8 O=C(COC(=O)CSc1cccc2cccc(Cl)c12)Nc1ncc(C(F)(F)F)cc1Cl nan
CHEMBL1305188 20227 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 5 5.8 O=C(COC(=O)CSc1cccc2cccc(Cl)c12)Nc1ncc(C(F)(F)F)cc1Cl nan
353380 20397 2 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 2 2 2 5.7 O=C(Nc1ccc(Br)c2ccccc12)c1ccc2ccccc2c1O nan
CHEMBL1306524 20397 2 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 2 2 2 5.7 O=C(Nc1ccc(Br)c2ccccc12)c1ccc2ccccc2c1O nan
4300736 20525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 3 2 7 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2c1 nan
CHEMBL1307550 20525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 3 2 7 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2c1 nan
16194293 20557 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 1 8 3.4 CCc1nnc(NC(=O)CSc2ccc(-c3cccs3)nn2)s1 nan
CHEMBL1307806 20557 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 1 8 3.4 CCc1nnc(NC(=O)CSc2ccc(-c3cccs3)nn2)s1 nan
24819826 20582 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 6 2 3 4.1 O=C(NCCCSc1ccccc1)c1cc(Br)ccc1O nan
CHEMBL1307980 20582 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 6 2 3 4.1 O=C(NCCCSc1ccccc1)c1cc(Br)ccc1O nan
713805 20638 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 0 9 0.6 COc1nc(N2CCCC2)nc(-n2nnc(C(C)=O)c2C)n1 nan
CHEMBL1308437 20638 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 0 9 0.6 COc1nc(N2CCCC2)nc(-n2nnc(C(C)=O)c2C)n1 nan
935829 20656 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 0 4 3.3 Cc1nc2ccccc2nc1SCC(=O)N1CCC(C)CC1 nan
CHEMBL1308605 20656 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 0 4 3.3 Cc1nc2ccccc2nc1SCC(=O)N1CCC(C)CC1 nan
2815890 20701 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 5 10 -1.9 CNc1nc2c(N)ncnc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O nan
CHEMBL1308946 20701 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 5 10 -1.9 CNc1nc2c(N)ncnc2n1[C@H]1O[C@@H](CO)[C@H](O)[C@@H]1O nan
4619601 20708 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 0 7 2.2 CCN(C(=O)CSC1=Nc2ccccc2C2CC=NN12)C1CCS(=O)(=O)C1 nan
CHEMBL1309010 20708 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 0 7 2.2 CCN(C(=O)CSC1=Nc2ccccc2C2CC=NN12)C1CCS(=O)(=O)C1 nan
4038913 20801 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.9 CCN(C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12)C1CCS(=O)(=O)C1 nan
CHEMBL1309767 20801 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.9 CCN(C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12)C1CCS(=O)(=O)C1 nan
20923170 20898 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1C nan
CHEMBL1310648 20898 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 2.7 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NC1CCCCC1C nan
3163618 20935 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.6 Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)s2)cc1 nan
CHEMBL1310953 20935 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.6 Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)s2)cc1 nan
1504615 20984 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 6 2.0 Cc1cc(CNC(=O)Cn2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
CHEMBL1311384 20984 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 6 2.0 Cc1cc(CNC(=O)Cn2cc([N+](=O)[O-])cn2)c2ccccc2n1 nan
652682 21043 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 8 1 6 4.3 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1311808 21043 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 8 1 6 4.3 C=CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2ccncc2)c1 nan
24892134 21060 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 2.7 Cn1c(=O)c2c(SCC(=O)Nc3ccccc3F)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1311956 21060 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 2.7 Cn1c(=O)c2c(SCC(=O)Nc3ccccc3F)nc(-c3ccccc3F)nc2n(C)c1=O nan
2769005 21233 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 4 0 7 1.1 CCOC(=O)CSc1nc(=O)n2cc(C)ccc2n1 nan
CHEMBL1313156 21233 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 4 0 7 1.1 CCOC(=O)CSc1nc(=O)n2cc(C)ccc2n1 nan
20914264 21236 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.9 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)cc1 nan
CHEMBL1313185 21236 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 1.9 O=C1c2cccnc2C(=O)N1Cc1ccc(S(=O)(=O)NCc2ccco2)cc1 nan
4002385 21259 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
662194 21259 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1313374 21259 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CC(C)Oc1ccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
16033288 21384 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 5.3 Cc1ccc(C)c(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
CHEMBL1314411 21384 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 5.3 Cc1ccc(C)c(CNC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)c1 nan
1046209 21452 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 2 1 8 2.8 Cn1c(=O)c2c(nc3n(-c4ccc(O)cc4)c(-c4ccc(Br)cc4)cn23)n(C)c1=O nan
CHEMBL1315398 21452 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 2 1 8 2.8 Cn1c(=O)c2c(nc3n(-c4ccc(O)cc4)c(-c4ccc(Br)cc4)cn23)n(C)c1=O nan
16014663 21463 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 6 3.8 COc1ccc(-c2nsc(NC(=O)COc3ccc(C)c(C)c3)n2)cc1 nan
CHEMBL1315498 21463 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 1 6 3.8 COc1ccc(-c2nsc(NC(=O)COc3ccc(C)c(C)c3)n2)cc1 nan
16017636 21511 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 5 2 8 4.3 COc1ccc(NC(=O)c2sc3nc(-c4cc5ccc(OC)cc5oc4=O)[nH]c(=O)c3c2C)cc1 nan
CHEMBL1316057 21511 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 5 2 8 4.3 COc1ccc(NC(=O)c2sc3nc(-c4cc5ccc(OC)cc5oc4=O)[nH]c(=O)c3c2C)cc1 nan
16018724 21517 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 7 4.2 COc1ccc(Cl)cc1NC(=O)CSc1nnc(C)n2c1cc1occc12 nan
CHEMBL1316127 21517 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 7 4.2 COc1ccc(Cl)cc1NC(=O)CSc1nnc(C)n2c1cc1occc12 nan
16009825 21570 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc(OC)c1 nan
CHEMBL1316937 21570 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc(OC)c1 nan
24980344 21573 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 5 3.0 Cc1ccc(C(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
CHEMBL1316966 21573 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 5 3.0 Cc1ccc(C(=O)NCC(=O)OCC(=O)c2ccc(Br)s2)cc1 nan
7159295 21592 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 6 1 9 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O nan
CHEMBL1317213 21592 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 6 1 9 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O nan
17757011 21597 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 2 1 4 5.3 O=C1COc2ccc(-c3cc(-c4ccccc4)c4c(n3)-c3ccccc3OC4)cc2N1 nan
CHEMBL1317304 21597 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 2 1 4 5.3 O=C1COc2ccc(-c3cc(-c4ccccc4)c4c(n3)-c3ccccc3OC4)cc2N1 nan
1215486 21598 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 5.6 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1317307 21598 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 5.6 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(F)cc1 nan
4318326 21751 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 1 6 3.1 COc1ccc2nc(C)cc(SCC(NC(C)=O)C(=O)OC(C)C)c2c1 nan
CHEMBL1318910 21751 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 1 6 3.1 COc1ccc2nc(C)cc(SCC(NC(C)=O)C(=O)OC(C)C)c2c1 nan
621902 21755 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 5 0 5 3.5 CCSc1cnn(-c2ccccc2)c(=O)c1SCC nan
CHEMBL1318957 21755 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 5 0 5 3.5 CCSc1cnn(-c2ccccc2)c(=O)c1SCC nan
3152777 21881 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3cccc(O)c3)sc2c1 nan
CHEMBL1320029 21881 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3cccc(O)c3)sc2c1 nan
15990516 22001 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.1 COc1ccc2nc3sc(C(=O)NCCc4ccc(Cl)cc4)cc3cc2c1 nan
CHEMBL1321040 22001 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 4 5.1 COc1ccc2nc3sc(C(=O)NCCc4ccc(Cl)cc4)cc3cc2c1 nan
2158383 22230 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1323129 22230 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
864393 22290 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.1 Cc1cc(SCC(=O)NC2CCCCC2)nc2ccccc12 nan
CHEMBL1323679 22290 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.1 Cc1cc(SCC(=O)NC2CCCCC2)nc2ccccc12 nan
2138908 22318 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 5.0 CCOC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1323878 22318 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 5.0 CCOC(=O)c1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
716947 22373 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 3.9 CCOc1ccc(-c2oc3ccc(C)cc3c(=O)c2O)cc1 nan
CHEMBL1324368 22373 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 3.9 CCOc1ccc(-c2oc3ccc(C)cc3c(=O)c2O)cc1 nan
2929091 22382 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.2 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCC1 nan
CHEMBL1324435 22382 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 7 2.2 N=c1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc2n1C1CCCC1 nan
16017079 22404 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 4 1 5 6.2 CCC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1324580 22404 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 4 1 5 6.2 CCC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)n1nc(C)c2sc3ccccc3c2c1=O nan
6619868 22437 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 2 5 3.4 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)cc1 nan
CHEMBL1324841 22437 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 2 5 3.4 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)cc1 nan
135415532 22511 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 7 2.6 Cc1cc(O)nc(SCc2nc3ncccn3c2Br)n1 nan
CHEMBL1325556 22511 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 7 2.6 Cc1cc(O)nc(SCc2nc3ncccn3c2Br)n1 nan
1086445 22634 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 6 3.7 COc1ccc(-c2ccc3c(N)c(C(=O)NC(C)C)sc3n2)cc1OC nan
CHEMBL1326816 22634 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 6 3.7 COc1ccc(-c2ccc3c(N)c(C(=O)NC(C)C)sc3n2)cc1OC nan
5739163 22693 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1327274 22693 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCO2 nan
2128134 22716 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 0 5 2.3 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cccnc2Cl)c1 nan
CHEMBL1327541 22716 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 0 5 2.3 CN(C)S(=O)(=O)c1cccc(COC(=O)c2cccnc2Cl)c1 nan
5899385 22773 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 1 7 3.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3cccnc3)ccc2O1 nan
CHEMBL1327895 22773 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 1 7 3.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(CCCn4ccnc4)C3c3cccnc3)ccc2O1 nan
3464558 22808 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 5 3.3 COc1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)CC2)cc1 nan
CHEMBL1328124 22808 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 5 3.3 COc1ccc(S(=O)(=O)N2CCN(CC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)CC2)cc1 nan
1779937 22973 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 1 4 4.3 COc1ccc2sc3c(O)nc4ccccc4c3c2c1 nan
CHEMBL1329604 22973 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 1 4 4.3 COc1ccc2sc3c(O)nc4ccccc4c3c2c1 nan
16013718 23095 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 3.7 CCc1nonc1NC(=O)c1oc2ccc(Br)cc2c1C nan
CHEMBL1330644 23095 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 3.7 CCc1nonc1NC(=O)c1oc2ccc(Br)cc2c1C nan
2991043 23302 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 0.4 Cn1c(=O)c2c(nc(CN3CCc4ccccc4C3)n2CCCO)n(C)c1=O nan
CHEMBL1332170 23302 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 8 0.4 Cn1c(=O)c2c(nc(CN3CCc4ccccc4C3)n2CCCO)n(C)c1=O nan
1861856 23375 13 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 2 6 2.5 COc1cc2[nH]c(=S)n(NC(=O)c3ccccc3)c(=O)c2cc1OC nan
CHEMBL1332727 23375 13 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 2 6 2.5 COc1cc2[nH]c(=S)n(NC(=O)c3ccccc3)c(=O)c2cc1OC nan
5302228 23746 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 0 6 3.3 COc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccc(Cl)cn23)cc1 nan
CHEMBL1335569 23746 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 0 6 3.3 COc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccc(Cl)cn23)cc1 nan
16018981 23825 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 4.3 O=C(NCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1336206 23825 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 4.3 O=C(NCc1ccccc1Cl)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2807849 23847 69 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 2 1 3 3.2 CC(=O)c1sc(-c2ccccc2)cc1N nan
CHEMBL1336437 23847 69 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 2 1 3 3.2 CC(=O)c1sc(-c2ccccc2)cc1N nan
2222525 23867 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 7 3.0 CC(=O)c1sc2nc(SCC(=O)N3CCCCC3)nc(O)c2c1C nan
CHEMBL1336564 23867 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 7 3.0 CC(=O)c1sc2nc(SCC(=O)N3CCCCC3)nc(O)c2c1C nan
2844395 23926 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 4 2 3 1.3 CC(C)NC(=O)CC(=O)NN=C1CCCCC1 nan
CHEMBL1337153 23926 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 4 2 3 1.3 CC(C)NC(=O)CC(=O)NN=C1CCCCC1 nan
1480701 24038 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 2.0 COC(=O)c1nc2ccc(N3CCOCC3)cc2c(C)c1C(=O)OC nan
CHEMBL1338156 24038 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 7 2.0 COC(=O)c1nc2ccc(N3CCOCC3)cc2c(C)c1C(=O)OC nan
861738 24076 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc(SCC(=O)NC2CCCC2)nc2ccccc12 nan
CHEMBL1338383 24076 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 4 1 3 3.7 Cc1cc(SCC(=O)NC2CCCC2)nc2ccccc12 nan
4677074 24442 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 1 3 2.8 Sc1nc2ccccc2n2cccc12 nan
CHEMBL1341748 24442 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 1 3 2.8 Sc1nc2ccccc2n2cccc12 nan
2334933 24512 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 4 3.5 O=C(COC(=O)CSc1ccc2ccccc2c1Br)NC1CC1 nan
CHEMBL1342297 24512 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 4 3.5 O=C(COC(=O)CSc1ccc2ccccc2c1Br)NC1CC1 nan
650550 24577 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 0 6 3.4 COc1ccc(-c2nsc3c(N4CCCC4)ncnc23)cc1 nan
CHEMBL1342739 24577 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 0 6 3.4 COc1ccc(-c2nsc3c(N4CCCC4)ncnc23)cc1 nan
16445815 24738 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
CHEMBL1344160 24738 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 8 3.8 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(F)cc2)s1 nan
7190688 24764 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1344377 24764 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
3106500 24789 9 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 7 1.5 CC1=NN(C(N)=S)C(=O)C1N=Nc1ccc([N+](=O)[O-])cc1 nan
CHEMBL1344603 24789 9 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 3 1 7 1.5 CC1=NN(C(N)=S)C(=O)C1N=Nc1ccc([N+](=O)[O-])cc1 nan
20907339 24848 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 5 2.6 CCOCCCNC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
CHEMBL1345074 24848 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 6 1 5 2.6 CCOCCCNC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
6103434 24988 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 7 3.7 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1346374 24988 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 7 3.7 CCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
2122298 25123 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 1 5 2.7 CC(=O)c1sc(NC(=O)COc2ccccc2)nc1C nan
CHEMBL1347404 25123 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 1 5 2.7 CC(=O)c1sc(NC(=O)COc2ccccc2)nc1C nan
899068 25171 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 1 6 3.6 CSc1nc(S)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1347767 25171 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 1 6 3.6 CSc1nc(S)c2c3c(sc2n1)COC(C)(C)C3 nan
1481616 25237 21 None -15 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 0 4 4.3 COc1cccc(CSc2nc3ccccc3cc2C=O)c1 nan
CHEMBL1348389 25237 21 None -15 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 0 4 4.3 COc1cccc(CSc2nc3ccccc3cc2C=O)c1 nan
1378026 25257 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.2 COc1ccc(NC(=O)c2ccc(C(=O)c3cc(OC)ccc3OC)cc2)cc1 nan
CHEMBL1348606 25257 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.2 COc1ccc(NC(=O)c2ccc(C(=O)c3cc(OC)ccc3OC)cc2)cc1 nan
2205361 25260 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 4 3 9 2.3 COC(=O)c1sc(N=C(S)NNC(=O)c2c(Br)c(C)nn2C)c(C(=O)OC)c1C nan
CHEMBL1348642 25260 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 4 3 9 2.3 COC(=O)c1sc(N=C(S)NNC(=O)c2c(Br)c(C)nn2C)c(C(=O)OC)c1C nan
2084877 25274 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 1 5 3.8 COCCNC(=O)CSc1cc(-c2ccccc2)c2ccc(OC)cc2n1 nan
CHEMBL1348812 25274 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 8 1 5 3.8 COCCNC(=O)CSc1cc(-c2ccccc2)c2ccc(OC)cc2n1 nan
1256964 25280 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 1 4 5.1 O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
CHEMBL1348841 25280 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 1 4 5.1 O=C(NCc1cccs1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
3783556 25360 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.0 C=CCN1C(=O)NC(=O)/C(=C\Nc2c(C)n(C)n(-c3ccccc3)c2=O)C1=O nan
CHEMBL1349443 25360 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 2 7 1.0 C=CCN1C(=O)NC(=O)/C(=C\Nc2c(C)n(C)n(-c3ccccc3)c2=O)C1=O nan
24746879 25373 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.5 COC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1349543 25373 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.5 COC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
4831863 25453 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 0.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)Cn1nnc2ccccc2c1=O nan
CHEMBL1350232 25453 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 0.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)Cn1nnc2ccccc2c1=O nan
663661 25489 16 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 5 4.5 c1ccc2[nH]c(CSc3ncnc4c3oc3ccccc34)nc2c1 nan
CHEMBL1350581 25489 16 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 5 4.5 c1ccc2[nH]c(CSc3ncnc4c3oc3ccccc34)nc2c1 nan
2881707 25618 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 3.2 Cc1nnc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2ccccc12 nan
CHEMBL1351647 25618 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 3.2 Cc1nnc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2ccccc12 nan
5308898 25635 63 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 1 3 2.4 CCc1cc(=O)oc2cc(C)cc(O)c12 nan
CHEMBL1351746 25635 63 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 1 3 2.4 CCc1cc(=O)oc2cc(C)cc(O)c12 nan
2802516 25690 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.2 Sc1nc(-c2ccccc2)n(-c2ccccc2)n1 nan
CHEMBL1352266 25690 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.2 Sc1nc(-c2ccccc2)n(-c2ccccc2)n1 nan
1435022 25780 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 6 4.3 CCc1nc(SCC(=O)Nc2nc3c(s2)CCCC3)c2ccccc2n1 nan
CHEMBL1352936 25780 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 6 4.3 CCc1nc(SCC(=O)Nc2nc3c(s2)CCCC3)c2ccccc2n1 nan
7285290 25814 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 2 3.5 Cc1nc(-c2ccc(Br)cc2)ccc1C(=O)O nan
CHEMBL1353200 25814 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 2 1 2 3.5 Cc1nc(-c2ccc(Br)cc2)ccc1C(=O)O nan
15989677 25977 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc(OC)c1 nan
CHEMBL1354335 25977 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1cc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc(OC)c1 nan
16030401 26013 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 8 1 4 5.0 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)cc1 nan
CHEMBL1354835 26013 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 8 1 4 5.0 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCCc2ccccc2)cc1 nan
16010860 26016 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 2.8 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1 nan
CHEMBL1354858 26016 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 2.8 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1 nan
15988167 26079 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.9 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 nan
CHEMBL1355668 26079 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.9 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 nan
16024817 26179 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1356900 26179 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 1 4 5.2 O=C(Nc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
1165987 26285 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 6 4.0 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCC(C)C)n2)cc1OC nan
CHEMBL1358322 26285 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 6 4.0 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCC(C)C)n2)cc1OC nan
1003453 26300 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 2 5 5.6 Nc1c(C(=O)Nc2ccccc2Br)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1358598 26300 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 2 5 5.6 Nc1c(C(=O)Nc2ccccc2Br)sc2nc(-c3cccs3)ccc12 nan
663400 26347 13 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.8 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(Cl)c1 nan
CHEMBL1359009 26347 13 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.8 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(Cl)c1 nan
5104589 26428 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 3 6.6 O=C(Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1)c1ccc2ccccc2c1 nan
CHEMBL1359625 26428 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 3 1 3 6.6 O=C(Nc1ccc2oc(-c3ccc(Cl)cc3)nc2c1)c1ccc2ccccc2c1 nan
4438847 26555 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 1.1 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1cccc[n+]1[O-] nan
CHEMBL1360781 26555 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 1.1 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1cccc[n+]1[O-] nan
15989315 26557 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 10 1 7 4.6 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4ccccc4n(Cc4cccc(C)c4)c3=O)cc2)cc1OC nan
CHEMBL1360796 26557 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 10 1 7 4.6 COc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4ccccc4n(Cc4cccc(C)c4)c3=O)cc2)cc1OC nan
15991495 26593 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 3 5 3.9 O=C(O)Cc1sc(Nc2ccc(C(=O)O)cc2)nc1-c1ccccc1 nan
CHEMBL1361126 26593 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 3 5 3.9 O=C(O)Cc1sc(Nc2ccc(C(=O)O)cc2)nc1-c1ccccc1 nan
2816171 26641 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 8 1.3 CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1ccccc12 nan
CHEMBL1361598 26641 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 0 8 1.3 CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1ccccc12 nan
6238059 26712 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 2 6 2.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccc(F)cc2)cc1 nan
CHEMBL1362160 26712 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 2 6 2.8 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2ccc(F)cc2)cc1 nan
15988824 26728 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 7 4.2 COc1ccc(-c2cc(C(=O)Nc3ccn(Cc4ccc(C)cc4)n3)no2)cc1OC nan
CHEMBL1362337 26728 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 7 4.2 COc1ccc(-c2cc(C(=O)Nc3ccn(Cc4ccc(C)cc4)n3)no2)cc1OC nan
6625370 27048 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 7 2.2 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(F)c3)sc2n1 nan
CHEMBL1365096 27048 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 7 2.2 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(F)c3)sc2n1 nan
1315619 27081 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 3 5 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1C(=O)NCc1ccco1)c1ccco1 nan
CHEMBL1365331 27081 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 3 5 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1C(=O)NCc1ccco1)c1ccco1 nan
2138525 27100 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 7 4.6 Cc1ccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)cc1 nan
CHEMBL1365483 27100 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 7 4.6 Cc1ccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)cc1 nan
5068934 27149 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 3 3.0 O=C(CCS(=O)(=O)Cc1cccc(Cl)c1)NCCc1ccccc1 nan
CHEMBL1365953 27149 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 8 1 3 3.0 O=C(CCS(=O)(=O)Cc1cccc(Cl)c1)NCCc1ccccc1 nan
7190319 27151 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 3 0 6 3.0 CCSc1ccc2nnc(-c3cccs3)n2n1 nan
CHEMBL1365969 27151 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 3 0 6 3.0 CCSc1ccc2nnc(-c3cccs3)n2n1 nan
16194607 27329 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 10 1 7 1.7 CCN(CC)CCCNC(=O)Cn1cnc2ccc(S(=O)(=O)N3CCC(C)CC3)cc2c1=O nan
CHEMBL1367480 27329 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 10 1 7 1.7 CCN(CC)CCCNC(=O)Cn1cnc2ccc(S(=O)(=O)N3CCC(C)CC3)cc2c1=O nan
16033554 27460 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 4 1.7 CC(=O)Nc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 nan
CHEMBL1368494 27460 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 4 1.7 CC(=O)Nc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 nan
16009410 27551 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 5.2 CCC(CC)c1nn2c(=O)cc(COc3ccc(NC(=O)c4ccccc4C)cc3)nc2s1 nan
CHEMBL1369161 27551 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 5.2 CCC(CC)c1nn2c(=O)cc(COc3ccc(NC(=O)c4ccccc4C)cc3)nc2s1 nan
20880788 27711 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 3.4 CC1CCCC(C)N1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
CHEMBL1370306 27711 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 3.4 CC1CCCC(C)N1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
2622707 27781 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 0 6 2.9 O=[N+]([O-])c1cccc(CSc2nnc3ccccn23)c1 nan
CHEMBL1370729 27781 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 0 6 2.9 O=[N+]([O-])c1cccc(CSc2nnc3ccccn23)c1 nan
3178485 27834 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCn1c(SCC(=O)N2CCCCC2C)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1371157 27834 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.9 CCn1c(SCC(=O)N2CCCCC2C)nc2c1c(=O)n(C)c(=O)n2C nan
2155682 28025 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 4 0 5 3.1 CC1CCN(C(=O)CSc2nnc(-c3ccccc3)o2)CC1 nan
CHEMBL1372587 28025 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 4 0 5 3.1 CC1CCN(C(=O)CSc2nnc(-c3ccccc3)o2)CC1 nan
2965534 28047 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 5 5.1 CCOc1ccc(-c2cc(C(=O)NCCCn3ccnc3)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1372738 28047 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 1 5 5.1 CCOc1ccc(-c2cc(C(=O)NCCCn3ccnc3)c3cc(Br)ccc3n2)cc1 nan
2562079 28223 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 1 5 2.6 O=C(O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1373813 28223 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 1 5 2.6 O=C(O)CSc1ncnc2c1oc1ccccc12 nan
2478421 28378 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 1 7 0.8 CC1(C)NC(=O)N(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)C1=O nan
CHEMBL1374872 28378 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 1 7 0.8 CC1(C)NC(=O)N(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)C1=O nan
3122786 28447 19 None -10 4 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 4 5.1 COc1ccc(C2CC(c3cccs3)=NN2c2ccccc2)cc1 nan
CHEMBL1375375 28447 19 None -10 4 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 0 4 5.1 COc1ccc(C2CC(c3cccs3)=NN2c2ccccc2)cc1 nan
4077805 28529 30 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 5 3.9 C=CCn1c(=S)[nH]c2scc(-c3ccc(C)o3)c2c1=O nan
CHEMBL1376201 28529 30 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 5 3.9 C=CCn1c(=S)[nH]c2scc(-c3ccc(C)o3)c2c1=O nan
2815476 28612 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 4 4.6 O=S(=O)(Nc1ccccc1C(F)(F)F)c1ccc(-c2ccccn2)s1 nan
CHEMBL1376936 28612 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 4 4.6 O=S(=O)(Nc1ccccc1C(F)(F)F)c1ccc(-c2ccccn2)s1 nan
16016416 28648 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 5 3.6 Cc1cc(O)c(CN2CCN(c3ccc(F)cc3)CC2)c2oc(=O)cc(C)c12 nan
CHEMBL1377283 28648 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 5 3.6 Cc1cc(O)c(CN2CCN(c3ccc(F)cc3)CC2)c2oc(=O)cc(C)c12 nan
2400757 28682 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 2.1 O=C(CNC(=O)c1cccc(F)c1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1377678 28682 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 2.1 O=C(CNC(=O)c1cccc(F)c1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
2864532 28735 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 3 4.2 CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccccc2)C1c1ccccc1 nan
CHEMBL1378083 28735 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 3 4.2 CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccccc2)C1c1ccccc1 nan
3522811 28791 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 8 0.8 Cc1nc(SCC(=O)NCCc2ccccc2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1378692 28791 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 8 0.8 Cc1nc(SCC(=O)NCCc2ccccc2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
4647380 28866 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 12 1 9 0.8 COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(COC)o2)cc1 nan
CHEMBL1379293 28866 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 12 1 9 0.8 COCCN(CCOC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(COC)o2)cc1 nan
5904589 28968 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 2 6 3.9 O=C(C1=C(O)C(=O)N(Cc2ccccc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1380259 28968 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 2 6 3.9 O=C(C1=C(O)C(=O)N(Cc2ccccc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
2768996 29017 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 6 2.2 O=c1c2ccccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
CHEMBL1380557 29017 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 6 2.2 O=c1c2ccccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
2815634 29033 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 4 5.8 O=C(Nc1ccc(F)cc1)Nc1sccc1-c1nc2ccccc2s1 nan
CHEMBL1380666 29033 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 2 4 5.8 O=C(Nc1ccc(F)cc1)Nc1sccc1-c1nc2ccccc2s1 nan
3604840 29043 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
CHEMBL1380782 29043 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
723113 29063 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 2 4 4 3.9 Nc1ccc2[nH]c(-c3ccc(-c4nc5cc(N)ccc5[nH]4)cc3)nc2c1 nan
CHEMBL1380889 29063 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 2 4 4 3.9 Nc1ccc2[nH]c(-c3ccc(-c4nc5cc(N)ccc5[nH]4)cc3)nc2c1 nan
866607 29116 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1381324 29116 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
1247739 29296 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 6 4.6 Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Nc1nnc(C(F)(F)F)s1 nan
CHEMBL1382928 29296 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 6 4.6 Cc1onc(-c2c(F)cccc2Cl)c1C(=O)Nc1nnc(C(F)(F)F)s1 nan
4908738 29318 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 1 8 4.6 CCCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
CHEMBL1383134 29318 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 1 8 4.6 CCCSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccccc2F)s1 nan
4196061 29484 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 10 2 5 3.4 CCCCCNC(=O)c1ccc2c(=O)n(CCCOCC)c(=S)[nH]c2c1 nan
CHEMBL1384631 29484 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 10 2 5 3.4 CCCCCNC(=O)c1ccc2c(=O)n(CCCOCC)c(=S)[nH]c2c1 nan
1392125 29571 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 6 2.0 O=C1NC(=S)N(Cc2ccc(F)cc2)C(=O)/C1=C/NCc1ccc2c(c1)OCO2 nan
CHEMBL1385415 29571 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 6 2.0 O=C1NC(=S)N(Cc2ccc(F)cc2)C(=O)/C1=C/NCc1ccc2c(c1)OCO2 nan
20876328 29668 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 5 3.3 CN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(F)cc2)CCS3)CC1 nan
CHEMBL1386262 29668 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 1 5 3.3 CN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(F)cc2)CCS3)CC1 nan
17584980 29710 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 1 7 2.2 Cc1cc(O)c2c(C)c(CC(=O)N3CCN(C(=O)C4COc5ccccc5O4)CC3)c(=O)oc2c1 nan
CHEMBL1386530 29710 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 1 7 2.2 Cc1cc(O)c2c(C)c(CC(=O)N3CCN(C(=O)C4COc5ccccc5O4)CC3)c(=O)oc2c1 nan
3254139 29744 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.8 CSc1nc(SC(C)C(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1386773 29744 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 4 1 7 3.8 CSc1nc(SC(C)C(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
3220391 29795 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 7 1 6 2.1 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCCOC nan
CHEMBL1387168 29795 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 7 1 6 2.1 CCC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCCOC nan
16189864 29828 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 0 5 4.4 O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(Cc2cccn2-c2ncccn2)C1 nan
CHEMBL1387467 29828 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 0 5 4.4 O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(Cc2cccn2-c2ncccn2)C1 nan
899135 29871 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 3 3.2 NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
CHEMBL1387789 29871 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 3 3.2 NC(=O)c1cc(-c2cccnc2)nc2ccc(Br)cc12 nan
2360761 29872 26 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 1 5 2.5 COc1ccc2c(C)cc3nnc(S)n3c2c1 nan
CHEMBL1387791 29872 26 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 1 5 2.5 COc1ccc2c(C)cc3nnc(S)n3c2c1 nan
2377721 29915 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 0 6 3.9 Cc1cc(C)nc(Sc2ncnc3c2oc2ccccc23)n1 nan
CHEMBL1388175 29915 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 0 6 3.9 Cc1cc(C)nc(Sc2ncnc3c2oc2ccccc23)n1 nan
3303130 30079 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 6.0 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Oc3ccccc3)c2)n1 nan
CHEMBL1389429 30079 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 6.0 Cc1cccc(N2C(=O)C(O)=C(C(=O)c3cccs3)C2c2cccc(Oc3ccccc3)c2)n1 nan
5047557 30125 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 5 2.7 COC(=O)c1cc(C)sc1NC(=O)C1C2C=CC(CC2)C1C(=O)O nan
CHEMBL1389758 30125 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 5 2.7 COC(=O)c1cc(C)sc1NC(=O)C1C2C=CC(CC2)C1C(=O)O nan
671729 30188 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 4 3.8 O=C(Nc1ccc2c(c1)C(=O)N(c1ccccc1)C2=O)c1cccs1 nan
CHEMBL1390374 30188 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 4 3.8 O=C(Nc1ccc2c(c1)C(=O)N(c1ccccc1)C2=O)c1cccs1 nan
576025 30209 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 0 0 4 1.6 O=c1c2ccccc2c(=O)n2n1Cc1ccccc1C2 nan
CHEMBL1390537 30209 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 0 0 4 1.6 O=c1c2ccccc2c(=O)n2n1Cc1ccccc1C2 nan
1245900 30262 11 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 6 3.8 CCSc1nnc(NC(=O)c2cc3c(s2)CCCC3)s1 nan
CHEMBL1391017 30262 11 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 6 3.8 CCSc1nnc(NC(=O)c2cc3c(s2)CCCC3)s1 nan
5260648 30286 37 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 1 1 3 2.1 Cc1cc(Br)cn2cc(C(=O)O)nc12 nan
CHEMBL1391195 30286 37 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 254 1 1 3 2.1 Cc1cc(Br)cn2cc(C(=O)O)nc12 nan
6619983 30372 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 0 7 2.4 COC(=O)C(C)Sc1ccc2nnc(-c3ccccc3)n2n1 nan
CHEMBL1391987 30372 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 0 7 2.4 COC(=O)C(C)Sc1ccc2nnc(-c3ccccc3)n2n1 nan
3236381 30471 3 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 8 2.5 CCOC(=O)c1sc2ncnc(N3CCN(C(=O)OCC)CC3)c2c1C nan
CHEMBL1392800 30471 3 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 8 2.5 CCOC(=O)c1sc2ncnc(N3CCN(C(=O)OCC)CC3)c2c1C nan
135414599 30569 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 4 0.2 O=C1CC2C(=O)NCCN2C(NC(=O)c2ccc(Cl)cc2)=N1 nan
CHEMBL1393609 30569 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 4 0.2 O=C1CC2C(=O)NCCN2C(NC(=O)c2ccc(Cl)cc2)=N1 nan
950424 30667 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 0 7 1.6 CCN1CCN(c2nc3c(C)cccn3c(=O)c2C=C(C#N)C#N)CC1 nan
CHEMBL1394651 30667 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 0 7 1.6 CCN1CCN(c2nc3c(C)cccn3c(=O)c2C=C(C#N)C#N)CC1 nan
1689018 30681 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.2 CCOC(=O)c1sc2ncn(CC(=O)Nc3cc(C)cc(C)c3)c(=O)c2c1C nan
CHEMBL1394885 30681 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 7 3.2 CCOC(=O)c1sc2ncn(CC(=O)Nc3cc(C)cc(C)c3)c(=O)c2c1C nan
8087252 30745 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 0 5 4.3 COc1cccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)c1 nan
CHEMBL1395507 30745 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 0 5 4.3 COc1cccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3OC4)CC2)c1 nan
16009438 30754 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1 nan
CHEMBL1395616 30754 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1 nan
16017578 30789 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)cc1 nan
CHEMBL1396189 30789 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 7 2.5 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccco3)s2)cc1 nan
24819156 30806 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 0 6 6.1 COc1ccc(-c2oc3ccc(N4CCOCC4)cc3c2/C=C/c2ccc(OC)c(OC)c2)cc1 nan
CHEMBL1396464 30806 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 0 6 6.1 COc1ccc(-c2oc3ccc(N4CCOCC4)cc3c2/C=C/c2ccc(OC)c(OC)c2)cc1 nan
16022449 30843 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 4 4.9 CC(C)Oc1ccc(CNC(=O)c2cc3cccc4c3n2CC(C)S4)cc1 nan
CHEMBL1396952 30843 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 4 4.9 CC(C)Oc1ccc(CNC(=O)c2cc3cccc4c3n2CC(C)S4)cc1 nan
2017205 30863 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 2 6 5.8 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C(F)(F)F)cc4)sc3n2)cc1OC nan
CHEMBL1397215 30863 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 2 6 5.8 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(C(F)(F)F)cc4)sc3n2)cc1OC nan
16019456 30932 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 2.5 COc1cc(NS(=O)(=O)c2c(C)nc3sc(C)c(C)n3c2=O)cc(OC)c1 nan
CHEMBL1398166 30932 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 2.5 COc1cc(NS(=O)(=O)c2c(C)nc3sc(C)c(C)n3c2=O)cc(OC)c1 nan
2964735 30973 11 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cccc(C2C(C(=O)c3cc4cccc(OC)c4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
CHEMBL1398596 30973 11 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 7 1 9 4.5 COc1cccc(C2C(C(=O)c3cc4cccc(OC)c4o3)=C(O)C(=O)N2c2cc(C)on2)c1OC nan
16012160 30991 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 2.0 Cc1cc(=O)n2nc(N(C)CC(=O)NCc3cccc(Br)c3)sc2n1 nan
CHEMBL1398785 30991 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 2.0 Cc1cc(=O)n2nc(N(C)CC(=O)NCc3cccc(Br)c3)sc2n1 nan
20888752 31088 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 9 1.2 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
CHEMBL1399722 31088 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 9 1.2 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(CCO)CC2)s1 nan
7997207 31130 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 5 3.3 Cc1ccc(NC(=O)COC(=O)c2ccc(-n3cccn3)cc2)cc1C nan
CHEMBL1400115 31130 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 5 3.3 Cc1ccc(NC(=O)COC(=O)c2ccc(-n3cccn3)cc2)cc1C nan
2874407 31153 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.0 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CC(C)(C)CC2=N1 nan
CHEMBL1400295 31153 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.0 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CC(C)(C)CC2=N1 nan
2157035 31238 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 5.0 Cc1ccc(-c2nc(S(=O)(=O)c3ccccc3)c(SCC(=O)NC3CCCCC3)o2)cc1 nan
CHEMBL1401131 31238 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 5.0 Cc1ccc(-c2nc(S(=O)(=O)c3ccccc3)c(SCC(=O)NC3CCCCC3)o2)cc1 nan
5389771 31241 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 6 2.9 C=CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOC)C2c2cccnc2)cc1 nan
CHEMBL1401159 31241 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 6 2.9 C=CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOC)C2c2cccnc2)cc1 nan
20876293 31431 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 5 3.9 CCN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(C)cc2)CCS3)CC1 nan
CHEMBL1402721 31431 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 5 3.9 CCN1CCN(CCCNC(=O)c2ccc3c(c2)N(Cc2ccc(C)cc2)CCS3)CC1 nan
16025411 31434 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 7 3.3 COC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
CHEMBL1402769 31434 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 7 3.3 COC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
1091654 31541 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 2 5 4.5 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)COc1ccc(Cl)cc1C nan
CHEMBL1403849 31541 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 2 5 4.5 COc1ccc(NC(=O)c2ccco2)cc1NC(=O)COc1ccc(Cl)cc1C nan
2405342 31677 24 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2cc3c(cc2nc1Cl)OCCO3)c1ccccc1 nan
CHEMBL1405208 31677 24 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 6 2.9 O=S(=O)(Nc1nc2cc3c(cc2nc1Cl)OCCO3)c1ccccc1 nan
16018264 31712 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.7 CCOC(=O)c1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
CHEMBL1405564 31712 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.7 CCOC(=O)c1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1 nan
3258366 31821 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 2 6 3.5 CCC1(C)Cc2c(sc3nc(S)nc(S)c23)CO1 nan
CHEMBL1406514 31821 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 1 2 6 3.5 CCC1(C)Cc2c(sc3nc(S)nc(S)c23)CO1 nan
5739089 31869 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.7 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(F)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1407014 31869 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 6 3.7 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(F)c1)c1ccc2c(c1)OCO2 nan
20877853 32082 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 0 5 3.7 CCOC(=O)C1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
CHEMBL1408512 32082 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 0 5 3.7 CCOC(=O)C1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 nan
704023 32235 42 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 4 3.6 Sc1ncnc2sc(-c3ccccc3)cc12 nan
CHEMBL1409776 32235 42 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 1 1 4 3.6 Sc1ncnc2sc(-c3ccccc3)cc12 nan
4197372 32254 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.5 O=C(Nc1nc(-c2cccs2)c(C(=O)C(F)(F)F)s1)c1ccco1 nan
CHEMBL1409901 32254 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.5 O=C(Nc1nc(-c2cccs2)c(C(=O)C(F)(F)F)s1)c1ccco1 nan
1348850 32267 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cc(-c3nc4ccccc4s3)ccc2C)cc1 nan
CHEMBL1409994 32267 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cc(-c3nc4ccccc4s3)ccc2C)cc1 nan
6472686 32296 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 1.5 COc1cccc2cc(C(=O)NCCN3CCOCC3)oc12 nan
CHEMBL1410184 32296 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 1.5 COc1cccc2cc(C(=O)NCCN3CCOCC3)oc12 nan
16019689 32372 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 1 8 2.9 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
CHEMBL1410849 32372 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 1 8 2.9 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc(F)cc3)nnc12 nan
16025704 32459 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.5 COc1ccc(OC)c(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
CHEMBL1411590 32459 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.5 COc1ccc(OC)c(CNC(=O)c2ccc(N3Cc4ccccc4Oc4ncccc43)s2)c1 nan
15988174 32560 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 2 4 3.0 Cc1ccc(CCNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
CHEMBL1412411 32560 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 2 4 3.0 Cc1ccc(CCNC(=O)c2ccc3c(=O)n(-c4ccccc4)c(=O)[nH]c3c2)cc1 nan
972224 32613 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 5 3.8 CCc1c(C)sc(N=C(S)Nc2cccnc2)c1C(=O)OC nan
CHEMBL1412818 32613 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 5 3.8 CCc1c(C)sc(N=C(S)Nc2cccnc2)c1C(=O)OC nan
16018140 32623 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 2 4.5 Cn1cc(CCCC(=O)NCc2ccccc2Cl)c2ccccc21 nan
CHEMBL1412876 32623 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 2 4.5 Cn1cc(CCCC(=O)NCc2ccccc2Cl)c2ccccc21 nan
646994 32659 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.4 Cc1ccc(S(=O)(=O)N(Cc2cc3cc4c(cc3nc2O)OCCO4)CC2CCCO2)cc1 nan
CHEMBL1413144 32659 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.4 Cc1ccc(S(=O)(=O)N(Cc2cc3cc4c(cc3nc2O)OCCO4)CC2CCCO2)cc1 nan
16018722 32697 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 4.1 Cc1ccc(C)c(NC(=O)CSc2nnc(C)n3c2cc2occc23)c1 nan
CHEMBL1413449 32697 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 4.1 Cc1ccc(C)c(NC(=O)CSc2nnc(C)n3c2cc2occc23)c1 nan
4149556 32733 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 3 4.3 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1F nan
CHEMBL1413747 32733 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 3 4.3 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1F nan
16018046 32852 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 4 3.8 O=C(CCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1Cl nan
CHEMBL1414743 32852 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 4 3.8 O=C(CCn1c(=O)c2cccn2c2ccc(F)cc21)NCCc1ccccc1Cl nan
16187993 32909 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)NCc1ccccn1)C(=O)CO2 nan
CHEMBL1415247 32909 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 6 1.2 CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)NCc1ccccn1)C(=O)CO2 nan
2910208 33074 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.3 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(F)cc1)c1ccco1 nan
CHEMBL1416738 33074 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.3 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(F)cc1)c1ccco1 nan
5014048 33118 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 3 5.9 Cc1ccc(CCNC(=O)c2cc(Nc3ccc(C)c(C)c3)nc3ccccc23)cc1 nan
CHEMBL1417106 33118 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 3 5.9 Cc1ccc(CCNC(=O)c2cc(Nc3ccc(C)c(C)c3)nc3ccccc23)cc1 nan
8901980 33149 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 5 4.1 CCOC(=O)Nc1ccc2c(CN(C)Cc3ccc(F)cc3)cc(=O)oc2c1 nan
CHEMBL1417351 33149 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 5 4.1 CCOC(=O)Nc1ccc2c(CN(C)Cc3ccc(F)cc3)cc(=O)oc2c1 nan
2911345 33262 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
3999653 33262 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
CHEMBL1418370 33262 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 5 4.5 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Br)cc2)o1 nan
1388232 33334 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 1 1 4 5.2 Cc1cccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCc2ccccc2-4)c1 nan
CHEMBL1418971 33334 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 1 1 4 5.2 Cc1cccc(-n2c(=S)[nH]c3sc4c(c3c2=O)CCc2ccccc2-4)c1 nan
2077572 33380 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 1 6 1.9 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1419336 33380 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 5 1 6 1.9 O=C(CNC(=O)c1ccccc1)OCc1cc(=O)n2cc(Br)ccc2n1 nan
2370216 33717 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 0 3 4.2 O=C(COc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
CHEMBL1422190 33717 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 0 3 4.2 O=C(COc1c(Br)cc(Br)c2cccnc12)N1CCCCC1 nan
2035062 33740 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 2.6 CC(=O)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1422374 33740 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 2.6 CC(=O)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
16187581 33743 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 8 0 7 2.8 C=CCN(Cc1nc(-c2cc(OC)ccc2OC)oc1C)C1CCS(=O)(=O)C1 nan
CHEMBL1422392 33743 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 8 0 7 2.8 C=CCN(Cc1nc(-c2cc(OC)ccc2OC)oc1C)C1CCS(=O)(=O)C1 nan
5931057 33799 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 7 4.0 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1422871 33799 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 7 4.0 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
1609403 33898 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 0 5 4.7 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Br)cc2)c1 nan
CHEMBL1423632 33898 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 0 5 4.7 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Br)cc2)c1 nan
2308387 33933 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 0 8 2.6 Cc1c(CCOC(=O)c2cc([N+](=O)[O-])ccc2Cl)sc[n+]1CCCCS(=O)(=O)[O-] nan
CHEMBL1423887 33933 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 0 8 2.6 Cc1c(CCOC(=O)c2cc([N+](=O)[O-])ccc2Cl)sc[n+]1CCCCS(=O)(=O)[O-] nan
3546539 33998 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 1.2 O=C1NC(=S)N(C2CC2)C(=O)/C1=C/NCc1ccc(F)cc1 nan
CHEMBL1424530 33998 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 1.2 O=C1NC(=S)N(C2CC2)C(=O)/C1=C/NCc1ccc(F)cc1 nan
16192280 34144 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 4 4.2 CSc1ccc(C(=O)C2CCCN(C(=O)c3ccsc3)C2)cc1 nan
CHEMBL1425858 34144 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 4 4.2 CSc1ccc(C(=O)C2CCCN(C(=O)c3ccsc3)C2)cc1 nan
1229909 34420 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 6 2.7 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)n1 nan
CHEMBL1428119 34420 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 6 2.7 Cn1cc(Cl)c(-c2nnc(S)n2-c2ccc(F)cc2)n1 nan
20903654 34571 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 0 9 1.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
CHEMBL1429390 34571 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 0 9 1.6 CCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
3259805 34576 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 7 1.9 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COC(=O)c1cccnc1Cl nan
CHEMBL1429423 34576 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 7 1.9 Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COC(=O)c1cccnc1Cl nan
18562990 34623 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 2.0 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccc(F)cc1 nan
CHEMBL1429771 34623 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 2.0 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccc(F)cc1 nan
11834440 34642 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
4030418 34642 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
CHEMBL1429883 34642 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 4.9 CC(C)(C)c1ccc(/C(O)=C(/C([S-])=NCc2ccco2)[n+]2ccccc2)cc1 nan
3402414 34663 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -2.3 Cn1c(N)c(C(=O)COC(=O)C2=NNC(=O)CC2)c(=O)n(C)c1=O nan
CHEMBL1430091 34663 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 10 -2.3 Cn1c(N)c(C(=O)COC(=O)C2=NNC(=O)CC2)c(=O)n(C)c1=O nan
2578265 34667 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 6 1.8 CC1CCC2(CC1)NC(=O)N(Cc1cc(=O)n3ccsc3n1)C2=O nan
CHEMBL1430109 34667 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 1 6 1.8 CC1CCC2(CC1)NC(=O)N(Cc1cc(=O)n3ccsc3n1)C2=O nan
4987698 34938 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(O)c1)c1cc2ccccc2o1 nan
CHEMBL1432401 34938 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(O)c1)c1cc2ccccc2o1 nan
657881 34949 10 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 2 1 5 1.9 CCOC(=O)c1c(C)nsc1S nan
CHEMBL1432472 34949 10 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 2 1 5 1.9 CCOC(=O)c1c(C)nsc1S nan
5123174 34969 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 3.3 COCCCn1c(=S)[nH]c2c(sc3ccccc32)c1=O nan
CHEMBL1432655 34969 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 3.3 COCCCn1c(=S)[nH]c2c(sc3ccccc32)c1=O nan
16019017 35118 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 3.9 Cc1cccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c1 nan
CHEMBL1434147 35118 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 5 3.9 Cc1cccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c1 nan
3566323 35166 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 9 1 9 4.0 CCOC(=O)CC(NC(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)c1ccc(OCC)c(OC)c1 nan
CHEMBL1434864 35166 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 9 1 9 4.0 CCOC(=O)CC(NC(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)c1ccc(OCC)c(OC)c1 nan
16015297 35271 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.3 CCn1c(CN2CCC(C)CC2)nc2cc(NC(=O)COc3ccc(Cl)c(C)c3)ccc21 nan
CHEMBL1436095 35271 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.3 CCn1c(CN2CCC(C)CC2)nc2cc(NC(=O)COc3ccc(Cl)c(C)c3)ccc21 nan
7526401 35284 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 4 2.2 N#Cc1ccccc1NS(=O)(=O)c1cc2c3c(c1)CCN3C(=O)CC2 nan
CHEMBL1436243 35284 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 4 2.2 N#Cc1ccccc1NS(=O)(=O)c1cc2c3c(c1)CCN3C(=O)CC2 nan
16019444 35286 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.9 Cc1nc2sc(C)c(C)n2c(=O)c1S(=O)(=O)NCCc1ccc(Cl)cc1 nan
CHEMBL1436274 35286 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.9 Cc1nc2sc(C)c(C)n2c(=O)c1S(=O)(=O)NCCc1ccc(Cl)cc1 nan
1743255 35288 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 3 1 5 3.4 N#CCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccccc3)nc2c1Br nan
CHEMBL1436298 35288 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 3 1 5 3.4 N#CCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccccc3)nc2c1Br nan
1004082 35335 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 5 4.8 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(C)cc4)sc3n2)cc1 nan
CHEMBL1437042 35335 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 5 4.8 COc1ccc(-c2ccc3c(N)c(C(=O)NCc4ccc(C)cc4)sc3n2)cc1 nan
16030497 35365 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.8 CCc1cccc(C)c1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1437361 35365 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.8 CCc1cccc(C)c1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
5297283 35400 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 5 2.5 COc1ccc(C2CC(=O)Nc3c2c(=O)nc2c(C)cccn32)cc1 nan
CHEMBL1437774 35400 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 5 2.5 COc1ccc(C2CC(=O)Nc3c2c(=O)nc2c(C)cccn32)cc1 nan
2980985 35488 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 2 3 3.2 CC(C)(C)C(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
CHEMBL1438501 35488 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 2 3 3.2 CC(C)(C)C(=O)NNC(=O)COc1ccc2ccccc2c1Br nan
16027383 35521 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
CHEMBL1438820 35521 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 nan
16030423 35660 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.2 Cc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1 nan
CHEMBL1440057 35660 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 4 5.2 Cc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccc(C)cc2)cc1 nan
24816825 35670 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 3 3.4 O=C(c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1)N1CCC1 nan
CHEMBL1440121 35670 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 3 3.4 O=C(c1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1)N1CCC1 nan
22583638 35790 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 7 3.9 C=CCn1c(SCC(=O)N2CCN(c3ccccc3)CC2)nc2c3ccccc3nc-2c1O nan
CHEMBL1441228 35790 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 7 3.9 C=CCn1c(SCC(=O)N2CCN(c3ccccc3)CC2)nc2c3ccccc3nc-2c1O nan
4066521 35802 12 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 6 2.4 CC(=O)c1sc(NC(=O)C2COc3ccccc3O2)nc1C nan
CHEMBL1441350 35802 12 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 6 2.4 CC(=O)c1sc(NC(=O)C2COc3ccccc3O2)nc1C nan
2965654 35872 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 5 5.1 O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
CHEMBL1441978 35872 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 5 5.1 O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(-c2ccccn2)nc2c(Cl)cccc12 nan
16008702 35997 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 10 1 8 3.3 CCOC(=O)CC(NC(=O)CCc1c(C)nc2ncnn2c1C)c1ccc(OC(C)C)cc1 nan
CHEMBL1443046 35997 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 10 1 8 3.3 CCOC(=O)CC(NC(=O)CCc1c(C)nc2ncnn2c1C)c1ccc(OC(C)C)cc1 nan
2854033 36080 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 3 5.2 Fc1ccc(N2N=C(c3cccs3)CC2c2ccccc2)cc1 nan
CHEMBL1443903 36080 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 3 5.2 Fc1ccc(N2N=C(c3cccs3)CC2c2ccccc2)cc1 nan
5904887 36098 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
CHEMBL1444052 36098 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)cc1 nan
16249191 36259 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 2 10 0.0 CC(C)[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
CHEMBL1445550 36259 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 2 10 0.0 CC(C)[C@H](NS(=O)(=O)c1ccc(Cl)cc1)C(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O nan
6236858 36380 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccncc4)C3c3ccccc3F)ccc2O1 nan
CHEMBL1446709 36380 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 1 5 4.3 CC1Cc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccncc4)C3c3ccccc3F)ccc2O1 nan
2946413 36480 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 4 4.9 OC(COc1ccc2ccccc2c1Br)Cn1cnc(-c2ccccc2)c1 nan
CHEMBL1447526 36480 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 4 4.9 OC(COc1ccc2ccccc2c1Br)Cn1cnc(-c2ccccc2)c1 nan
5168521 36498 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 3.7 Cc1cc(C)c(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)c(C)c1 nan
CHEMBL1447670 36498 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 3.7 Cc1cc(C)c(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)c(C)c1 nan
975514 36648 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 2 3.7 COc1ccc2cc(Br)ccc2c1CC(=O)NC(C)C nan
CHEMBL1448872 36648 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 2 3.7 COc1ccc2cc(Br)ccc2c1CC(=O)NC(C)C nan
5003875 36977 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1Cl)c1cc(-c2ccc(Cl)cc2)on1 nan
CHEMBL1451527 36977 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1Cl)c1cc(-c2ccc(Cl)cc2)on1 nan
16009656 37040 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 6 4.8 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)cc2)c1 nan
CHEMBL1451944 37040 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 6 4.8 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)cc2)c1 nan
8087990 37056 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 0 8 1.3 Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)N1CCN(c2ccccn2)CC1 nan
CHEMBL1452085 37056 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 0 8 1.3 Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)N1CCN(c2ccccn2)CC1 nan
2172625 37065 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 2 6 2.6 Cc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)c(C)s1 nan
CHEMBL1452137 37065 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 2 6 2.6 Cc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)c(C)s1 nan
2874437 37124 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 0 10 -0.3 Cn1c(=O)c2c(ncn2CC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)n(C)c1=O nan
CHEMBL1452667 37124 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 0 10 -0.3 Cn1c(=O)c2c(ncn2CC(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)n(C)c1=O nan
3242606 37223 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 9 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc4c(c3)OCO4)nnc12 nan
CHEMBL1453430 37223 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 9 2.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccc4c(c3)OCO4)nnc12 nan
5924128 37270 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1453845 37270 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 6 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
16025308 37280 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 3.1 O=C(Cn1c2ncccc2c(=O)n1-c1ccccc1)Nc1ccc(F)c(F)c1 nan
CHEMBL1453921 37280 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 5 3.1 O=C(Cn1c2ncccc2c(=O)n1-c1ccccc1)Nc1ccc(F)c(F)c1 nan
16009318 37324 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 5 3.3 Cc1cc(C)cc(OCc2cc(=O)n3cc(C)sc3n2)c1 nan
CHEMBL1454181 37324 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 0 5 3.3 Cc1cc(C)cc(OCc2cc(=O)n3cc(C)sc3n2)c1 nan
16015117 37344 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccccc1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
CHEMBL1454422 37344 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccccc1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
20920416 37413 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1454925 37413 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
35802 37415 104 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 3 2 4 3.1 COC(=O)Nc1nc2cc(C(=O)c3ccc(F)cc3)ccc2[nH]1 nan
CHEMBL1454946 37415 104 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 3 2 4 3.1 COC(=O)Nc1nc2cc(C(=O)c3ccc(F)cc3)ccc2[nH]1 nan
5739327 37469 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCO2 nan
CHEMBL1455509 37469 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCO2 nan
20923165 37566 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 1 6 2.4 CCC(C)(C)NS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
CHEMBL1456385 37566 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 1 6 2.4 CCC(C)(C)NS(=O)(=O)c1cc(CN2C(=O)c3cccnc3C2=O)ccc1OC nan
3356561 37644 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.9 CCC1(C)Cc2c(sc3nc(SC)nc(S)c23)CO1 nan
CHEMBL1457175 37644 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.9 CCC1(C)Cc2c(sc3nc(SC)nc(S)c23)CO1 nan
16018620 37655 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.2 O=C(CSc1nncn2c1cc1occc12)Nc1ccccc1C(F)(F)F nan
CHEMBL1457242 37655 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 1 6 4.2 O=C(CSc1nncn2c1cc1occc12)Nc1ccccc1C(F)(F)F nan
24686163 37746 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 3 5.1 CCN(CC)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
CHEMBL1457962 37746 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 3 5.1 CCN(CC)C(=O)c1ccc(NC(=O)c2sccc2-c2ccccc2)cc1 nan
3927980 37783 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 6 3.1 CCCN1C(=O)C2(C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCCOC)c2ccccc21 nan
CHEMBL1458233 37783 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 6 3.1 CCCN1C(=O)C2(C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCCOC)c2ccccc21 nan
4962629 37817 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 4 3.5 Cc1cc(F)ccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1458588 37817 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 1 4 3.5 Cc1cc(F)ccc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
6460246 37818 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 5 3.1 Cc1nnc2c(SC(C)C)nc3ccccc3n12 nan
CHEMBL1458589 37818 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 5 3.1 Cc1nnc2c(SC(C)C)nc3ccccc3n12 nan
7475827 37897 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 0 9 0.2 CC(C)Cc1nc(SCC(=O)N2CCOCC2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1459222 37897 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 0 9 0.2 CC(C)Cc1nc(SCC(=O)N2CCOCC2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
3239559 38006 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 2 0 3 3.4 CCn1c(=S)ccc2ccc(OC)cc21 nan
CHEMBL1460186 38006 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 219 2 0 3 3.4 CCn1c(=S)ccc2ccc(OC)cc21 nan
4091063 38113 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 7 2.1 COC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
CHEMBL1461057 38113 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 7 2.1 COC(=O)c1ccc(NC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
135413805 38221 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 3 9 1.2 N#Cc1cc(Nc2c(N)ncnc2O)c([N+](=O)[O-])cc1C#N nan
CHEMBL1462053 38221 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 3 9 1.2 N#Cc1cc(Nc2c(N)ncnc2O)c([N+](=O)[O-])cc1C#N nan
4636986 38304 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 2 10 0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1462720 38304 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 2 10 0.2 Cc1cccn2c(=O)c3cc(C(=O)NCCN4CCOCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
993137 38341 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 3.4 CC(=O)c1sc(NC(=O)COc2ccc(Br)cc2)nc1C nan
CHEMBL1463012 38341 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 3.4 CC(=O)c1sc(NC(=O)COc2ccc(Br)cc2)nc1C nan
2225463 38396 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 3 3.3 O=C(NCCCN1CCCC1=O)c1sc2ccccc2c1Cl nan
CHEMBL1463545 38396 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 3 3.3 O=C(NCCCN1CCCC1=O)c1sc2ccccc2c1Cl nan
6184422 38467 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 10 1 8 3.5 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1464067 38467 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 10 1 8 3.5 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
135449395 38474 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 3.1 CCN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
CHEMBL1464106 38474 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 3.1 CCN(Cc1nc(O)c2ccccc2n1)Cc1nc(O)c2sccc2n1 nan
5778449 38562 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCOC)CC1 nan
CHEMBL1464778 38562 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NCCOC)CC1 nan
2457314 38573 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 10 0.1 COc1ccc(OC)c(/C=C/C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
CHEMBL1464838 38573 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 1 10 0.1 COc1ccc(OC)c(/C=C/C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 nan
3791918 38584 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)ccc2Cl)n1 nan
CHEMBL1464872 38584 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 1 2 3 3.1 Sc1n[nH]c(-c2cc(Cl)ccc2Cl)n1 nan
985269 38629 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 0 5 4.7 c1ccc(-c2cc3c(N4CCN(c5ccccc5)CC4)ncnc3s2)cc1 nan
CHEMBL1465210 38629 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 0 5 4.7 c1ccc(-c2cc3c(N4CCN(c5ccccc5)CC4)ncnc3s2)cc1 nan
1435001 38705 5 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 2 6 2.8 CCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
CHEMBL1465814 38705 5 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 2 6 2.8 CCc1nc(SCC(=O)NNC(=O)c2ccc(OC)cc2)c2ccccc2n1 nan
1479844 38743 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 4 5.2 CSc1nc(Sc2ccccc2Cl)c2ccccc2n1 nan
CHEMBL1466134 38743 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 4 5.2 CSc1nc(Sc2ccccc2Cl)c2ccccc2n1 nan
1836205 38746 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1466152 38746 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 8 0.8 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(C)CC2)nc2c(C)cccn2c1=O nan
2982726 38781 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 7 1.1 CCOC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1cccc([N+](=O)[O-])c1 nan
CHEMBL1466461 38781 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 7 1.1 CCOC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1cccc([N+](=O)[O-])c1 nan
5831389 38846 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 6 3.9 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1466919 38846 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 6 3.9 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
2161641 38902 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 2 7 3.0 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 nan
CHEMBL1467371 38902 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 7 2 7 3.0 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nccs2)cc1 nan
2146410 38904 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 2 3.3 CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
CHEMBL1467397 38904 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 2 3.3 CCNC(=O)Cc1c(OC)ccc2cc(Br)ccc12 nan
5028075 38940 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.9 COc1ccc(NC(=O)COC(=O)c2cc(SC)ccc2Cl)c(OC)c1 nan
CHEMBL1467702 38940 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 7 1 6 3.9 COc1ccc(NC(=O)COC(=O)c2cc(SC)ccc2Cl)c(OC)c1 nan
5786830 38951 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 3.4 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)cc1 nan
CHEMBL1467854 38951 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 3.4 COc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(F)cc2)cc1 nan
652110 39039 5 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 4 0 5 3.0 COC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
CHEMBL1468599 39039 5 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 4 0 5 3.0 COC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
20904121 39114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCOCC4)nn23)c1 nan
CHEMBL1469174 39114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCOCC4)nn23)c1 nan
5726945 39128 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 4 3.5 CC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
CHEMBL1469326 39128 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 4 3.5 CC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
3812545 39234 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(OC)c(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1470290 39234 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(OC)c(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2964736 39250 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(c4cc(C)on4)C3c3cccs3)oc12 nan
CHEMBL1470378 39250 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 4.6 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(c4cc(C)on4)C3c3cccs3)oc12 nan
15988466 39507 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.3 COc1ccc(NC(=O)Cn2c(=O)c3cc(Cl)ccc3n3nncc23)cc1 nan
CHEMBL1472605 39507 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.3 COc1ccc(NC(=O)Cn2c(=O)c3cc(Cl)ccc3n3nncc23)cc1 nan
16011470 39523 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(CCNC(=O)c2ccc(Cn3c(SCc4ccccc4)nc4cccnc43)cc2)cc1 nan
CHEMBL1472792 39523 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(CCNC(=O)c2ccc(Cn3c(SCc4ccccc4)nc4cccnc43)cc2)cc1 nan
6229347 39604 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 3.0 COc1ccccc1CCNC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
CHEMBL1473886 39604 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 3.0 COc1ccccc1CCNC(=O)Cc1c(C)c2c(O)cc(C)cc2oc1=O nan
20886471 39616 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 4 4.3 CCCOc1ccc(CNC(=O)c2ccc3c(c2)N(CC)CCS3)cc1 nan
CHEMBL1474147 39616 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 4 4.3 CCCOc1ccc(CNC(=O)c2ccc3c(c2)N(CC)CCS3)cc1 nan
15988056 39677 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 2 4 3.5 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(Cl)cc3)ccc2c1=O nan
CHEMBL1475000 39677 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 2 4 3.5 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(Cl)cc3)ccc2c1=O nan
5297460 39688 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 1 5 4.0 CCOc1ccc(-c2oc3ccccc3c(=O)c2O)cc1OCC nan
CHEMBL1475143 39688 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 1 5 4.0 CCOc1ccc(-c2oc3ccccc3c(=O)c2O)cc1OCC nan
16018222 39697 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 3.0 COc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1475268 39697 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 3.0 COc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
135410479 39707 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 2 4 5.5 Cc1ccc(NC(=O)c2cnn3c2NC(c2ccccc2)=CC3c2ccccc2)cc1 nan
CHEMBL1475406 39707 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 2 4 5.5 Cc1ccc(NC(=O)c2cnn3c2NC(c2ccccc2)=CC3c2ccccc2)cc1 nan
16031507 39708 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(F)c3)s2)cc1 nan
CHEMBL1475415 39708 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3cccc(F)c3)s2)cc1 nan
16015334 39771 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 6 5.7 COc1ccc(Cc2c(C)nn(-c3nc(C)c(C(=O)Nc4ccc(C)cc4C)s3)c2C)cc1 nan
CHEMBL1476342 39771 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 6 5.7 COc1ccc(Cc2c(C)nn(-c3nc(C)c(C(=O)Nc4ccc(C)cc4C)s3)c2C)cc1 nan
2033254 39818 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 7 2.8 CSc1nc(NCCCN(C)C)c2c3c(sc2n1)CN(C)CC3 nan
CHEMBL1476899 39818 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 6 1 7 2.8 CSc1nc(NCCCN(C)C)c2c3c(sc2n1)CN(C)CC3 nan
1138445 39917 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1477799 39917 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 2 9 1.5 CCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2c1c(=O)n(C)c(=O)n2C nan
1442565 39960 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 5 3.9 CCOC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
CHEMBL1478306 39960 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 6 0 5 3.9 CCOC(=O)CSc1nc(Cc2ccccc2)nc2ccccc12 nan
1005239 40054 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 2 1 5 5.8 N#Cc1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
CHEMBL1479144 40054 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 2 1 5 5.8 N#Cc1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
16018188 40082 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 1 5 3.8 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccccc32)cc1 nan
CHEMBL1479369 40082 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 1 5 3.8 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccccc32)cc1 nan
5914213 40573 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1483546 40573 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2ccncc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
796660 40657 4 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 5 2.9 COc1cc2oc(=O)c(Br)c(C)c2c(OC)c1OC nan
CHEMBL1484186 40657 4 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 5 2.9 COc1cc2oc(=O)c(Br)c(C)c2c(OC)c1OC nan
16025365 40731 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 7 1 7 5.4 CC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1484843 40731 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 7 1 7 5.4 CC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2)S3(=O)=O)c1 nan
2881633 40757 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 5 2.3 Cc1nnc(Nc2ccc(S(N)(=O)=O)cc2)c2ccccc12 nan
CHEMBL1485038 40757 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 5 2.3 Cc1nnc(Nc2ccc(S(N)(=O)=O)cc2)c2ccccc12 nan
16020293 40789 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 8 2 7 4.3 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(C)cc3)c2=O)cc1 nan
CHEMBL1485379 40789 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 562 8 2 7 4.3 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(C)cc3)c2=O)cc1 nan
866572 40837 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 6 1.3 CN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1485808 40837 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 6 1.3 CN1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
15991110 40856 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1c(F)cccc1F nan
CHEMBL1485996 40856 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1c(F)cccc1F nan
20869704 40860 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2cccc(OC)c2)c1=O nan
CHEMBL1486007 40860 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2cccc(OC)c2)c1=O nan
2951279 40861 13 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 7 4.2 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccco4)C3c3cccnc3)oc12 nan
CHEMBL1486010 40861 13 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 7 4.2 COc1cccc2cc(C(=O)C3=C(O)C(=O)N(Cc4ccco4)C3c3cccnc3)oc12 nan
3647805 40948 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 2 4 3.1 CCCCC(CC)CNC(=O)CC1N=C2c3ccccc3NC(=S)N2C1=O nan
CHEMBL1486794 40948 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 2 4 3.1 CCCCC(CC)CNC(=O)CC1N=C2c3ccccc3NC(=S)N2C1=O nan
3149629 40999 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 1 5 2.4 O=C(O)CSc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1487236 40999 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 1 5 2.4 O=C(O)CSc1ncnc2sc3c(c12)CCC3 nan
6296199 41010 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 8 2.9 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1487315 41010 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 9 1 8 2.9 C=CCOc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
3494131 41203 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccs2)no1 nan
CHEMBL1488696 41203 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 4.6 Cc1cc(N2C(=O)C(O)=C(C(=O)c3cc4ccccc4o3)C2c2cccs2)no1 nan
16016559 41257 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 1 4 3.7 Cc1ccc(-c2nonc2NC(=O)c2ccc(F)cc2)cc1C nan
CHEMBL1489095 41257 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 1 4 3.7 Cc1ccc(-c2nonc2NC(=O)c2ccc(F)cc2)cc1C nan
4604410 41423 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1c(Cl)cccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1490398 41423 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1c(Cl)cccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
15992220 41432 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
3862718 41432 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
5941821 41432 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
CHEMBL1490493 41432 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 1 2 4 0.9 CC(=O)N=C(N)Nc1nc(=O)c2ccccc2s1 nan
5307465 41565 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 0 6 2.5 Cc1sc2nc3ccc(N4CCCC4)nn3c(=O)c2c1C nan
CHEMBL1491386 41565 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 0 6 2.5 Cc1sc2nc3ccc(N4CCCC4)nn3c(=O)c2c1C nan
648659 41632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 8 1.5 CCCn1c(SCC(=O)N2CCc3ccccc3C2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1491811 41632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 8 1.5 CCCn1c(SCC(=O)N2CCc3ccccc3C2)nc2c1c(=O)n(C)c(=O)n2C nan
3240716 41647 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 11 2 7 3.9 CCOc1cc2[nH]c(=S)n(CCCCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
CHEMBL1491907 41647 10 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 11 2 7 3.9 CCOc1cc2[nH]c(=S)n(CCCCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
20917809 41672 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.1 O=C1c2cccnc2C(=O)N1Cc1ccc(F)cc1S(=O)(=O)NCc1ccco1 nan
CHEMBL1492082 41672 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 2.1 O=C1c2cccnc2C(=O)N1Cc1ccc(F)cc1S(=O)(=O)NCc1ccco1 nan
6533452 41685 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.4 COc1ccc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc1OC nan
CHEMBL1492209 41685 17 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.4 COc1ccc(/C=C2\CCc3c2nc2ccccc2c3C(=O)O)cc1OC nan
135414697 41698 14 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 3.7 N#Cc1c(O)nc(SCc2ccc(F)cc2)nc1-c1ccco1 nan
CHEMBL1492324 41698 14 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 6 3.7 N#Cc1c(O)nc(SCc2ccc(F)cc2)nc1-c1ccco1 nan
3151464 41736 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.1 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1492596 41736 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.1 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
3241814 41742 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 6 1.1 Cn1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1492641 41742 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 6 1.1 Cn1c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
4118355 41830 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 4 4.7 Cc1ccc(C(C)(C)C)cc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
CHEMBL1493417 41830 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 4 4.7 Cc1ccc(C(C)(C)C)cc1S(=O)(=O)Nc1nc2ccccc2nc1Cl nan
7899292 41837 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 8 1.5 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)c1 nan
CHEMBL1493482 41837 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 8 1.5 COc1cccc(C(=O)NCC(=O)OCc2cc(=O)n3c(C)csc3n2)c1 nan
16014523 41898 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 4.8 Cc1cc(Nc2ccc(C)c(Cl)c2)n2nc(-c3ccccc3)nc2n1 nan
CHEMBL1494140 41898 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 5 4.8 Cc1cc(Nc2ccc(C)c(Cl)c2)n2nc(-c3ccccc3)nc2n1 nan
4578483 41926 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 6 6.0 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(Cl)c4Cl)cc3n2)cc1OC nan
CHEMBL1494437 41926 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 6 6.0 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(Cl)c4Cl)cc3n2)cc1OC nan
2740372 41941 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 5 3.8 CCOC(=O)c1csc(-c2sccc2Br)n1 nan
CHEMBL1494595 41941 11 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 5 3.8 CCOC(=O)c1csc(-c2sccc2Br)n1 nan
6245779 41966 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 6 5.1 Cc1cc(OCc2ccccc2)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
CHEMBL1494772 41966 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 6 5.1 Cc1cc(OCc2ccccc2)ccc1C(=O)C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccncc1 nan
2961508 42016 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
5740308 42016 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
9587859 42016 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
CHEMBL1495283 42016 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.4 N=C(NOC(=O)COc1ccc2ccccc2c1Br)c1ccncc1 nan
7743649 42121 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 4 4.3 Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2c(C)cccc12 nan
CHEMBL1496365 42121 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 4 4.3 Cc1cc(SCC(=O)NC2(C#N)CCCCC2)nc2c(C)cccc12 nan
7709279 42178 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 3.1 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCS3 nan
CHEMBL1496847 42178 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 7 3.1 COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(=O)Nc1ccccc1)CCS3 nan
5760983 42179 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 4 1 4 5.4 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(Br)cc1)c1ccc(Br)cc1 nan
CHEMBL1496850 42179 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 4 1 4 5.4 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(Br)cc1)c1ccc(Br)cc1 nan
16195573 42212 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 2 7 3.2 CCOc1cc2[nH]c(=S)n(CCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
CHEMBL1497122 42212 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 9 2 7 3.2 CCOc1cc2[nH]c(=S)n(CCC(=O)NCc3ccco3)c(=O)c2cc1OCC nan
265605 42377 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 236 1 0 6 0.1 CC(C)c1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1498670 42377 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 236 1 0 6 0.1 CC(C)c1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
20875207 42556 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 3 4.2 O=C(Nc1ccccc1F)c1oc2ccccc2c1NC(=O)C1CC1 nan
CHEMBL1500175 42556 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 3 4.2 O=C(Nc1ccccc1F)c1oc2ccccc2c1NC(=O)C1CC1 nan
17583267 42627 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 3.8 COc1cc(NC(=O)COc2cc(C)cc3oc(=O)c(C)c(C)c23)cc(OC)c1OC nan
CHEMBL1500728 42627 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 7 3.8 COc1cc(NC(=O)COc2cc(C)cc3oc(=O)c(C)c(C)c23)cc(OC)c1OC nan
2768366 42825 59 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 3 2 4 2.2 COc1ccc(-c2ccc(C(=O)O)c(O)n2)cc1 nan
CHEMBL1502516 42825 59 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 245 3 2 4 2.2 COc1ccc(-c2ccc(C(=O)O)c(O)n2)cc1 nan
859554 42877 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 7 3.3 Cc1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)no1 nan
CHEMBL1503032 42877 17 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 1 7 3.3 Cc1cc(NC(=O)CSc2ncnc3sc(C)c(C)c23)no1 nan
5294012 42957 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 7 4.0 CC(C)n1c2ccccc2c2nnc(SCC(=O)Nc3ccccc3C(=O)O)nc21 nan
CHEMBL1503589 42957 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 7 4.0 CC(C)n1c2ccccc2c2nnc(SCC(=O)Nc3ccccc3C(=O)O)nc21 nan
20956972 43138 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 1.9 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)cc1F nan
CHEMBL1505377 43138 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 1.9 Cc1ccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)cc1F nan
4157311 43148 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 5 0 9 4.0 O=c1c2sccc2nc(SCc2cc(=O)n3cc(Br)ccc3n2)n1Cc1ccccn1 nan
CHEMBL1505478 43148 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 511 5 0 9 4.0 O=c1c2sccc2nc(SCc2cc(=O)n3cc(Br)ccc3n2)n1Cc1ccccn1 nan
5936247 43149 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccccc1C1C(C(=O)c2ccc3c(c2)OCCO3)=C(O)C(=O)N1Cc1cccnc1 nan
CHEMBL1505481 43149 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccccc1C1C(C(=O)c2ccc3c(c2)OCCO3)=C(O)C(=O)N1Cc1cccnc1 nan
3152549 43378 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1Cl)c1ccco1 nan
CHEMBL1507420 43378 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccccc1Cl)c1ccco1 nan
2905772 43395 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 11 -0.4 CCOC(=O)Cc1csc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 nan
CHEMBL1507551 43395 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 11 -0.4 CCOC(=O)Cc1csc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 nan
20888750 43407 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 8 1.8 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
CHEMBL1507635 43407 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 8 1.8 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
664007 43505 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 5 5.5 Cc1cc(NC(=O)c2ccc3nc(-c4ccccc4)c(-c4ccccc4)nc3c2)no1 nan
CHEMBL1508441 43505 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 5 5.5 Cc1cc(NC(=O)c2ccc3nc(-c4ccccc4)c(-c4ccccc4)nc3c2)no1 nan
1862355 43534 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1ccc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)cc1 nan
CHEMBL1508668 43534 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1ccc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)cc1 nan
6224737 43604 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 8 4.0 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1509331 43604 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 8 4.0 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
22514400 43682 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 7 0.6 CCOC(=O)C1CCN(C(=O)Cn2nc(C)n3cccc3c2=O)CC1 nan
CHEMBL1510088 43682 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 7 0.6 CCOC(=O)C1CCN(C(=O)Cn2nc(C)n3cccc3c2=O)CC1 nan
4547589 43706 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 3 4.9 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1Cl nan
CHEMBL1510328 43706 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 3 4.9 CC(C)(C)C(=O)C1=C(O)C(=O)N(Cc2ccccc2)C1c1ccccc1Cl nan
24792485 43727 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1cc2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2cc1OC nan
CHEMBL1510493 43727 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 1 8 3.2 COc1cc2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2cc1OC nan
6042599 43851 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)cc1 nan
CHEMBL1511435 43851 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CC2CCCO2)cc1 nan
16027534 43902 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)cc1 nan
CHEMBL1512013 43902 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)cc1 nan
16024951 43921 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 2 6 4.8 CCOc1ccc(Nc2nc(N)c(C(=O)c3ccccc3Cl)s2)cc1 nan
CHEMBL1512414 43921 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 6 2 6 4.8 CCOc1ccc(Nc2nc(N)c(C(=O)c3ccccc3Cl)s2)cc1 nan
4395410 44033 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 0 4 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCc1ccc(F)cc1 nan
CHEMBL1514024 44033 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 0 4 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCc1ccc(F)cc1 nan
16018164 44062 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 5 3.4 COc1ccccc1CNC(=O)CCCn1c(=O)c2cccn2c2ccccc21 nan
CHEMBL1514529 44062 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 7 1 5 3.4 COc1ccccc1CNC(=O)CCCn1c(=O)c2cccn2c2ccccc21 nan
4081154 44143 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 3 5.1 O=C(Nc1c(C(=O)c2ccccc2)oc2ccccc12)c1ccc(F)cc1 nan
CHEMBL1515694 44143 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 3 5.1 O=C(Nc1c(C(=O)c2ccccc2)oc2ccccc12)c1ccc(F)cc1 nan
135546812 44160 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 5 3.6 CCc1ccc(NC(=O)CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)cc1 nan
CHEMBL1515954 44160 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 2 5 3.6 CCc1ccc(NC(=O)CSc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)cc1 nan
16022285 44219 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 2 6 2.3 Cc1nc2cccnc2n1-c1cccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c1 nan
CHEMBL1516713 44219 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 2 6 2.3 Cc1nc2cccnc2n1-c1cccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c1 nan
1466061 44230 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 5 3.8 CCOc1ccc2nc(O)c(CN(CCc3ccccc3)C(=O)N3CCOCC3)cc2c1 nan
CHEMBL1516817 44230 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 5 3.8 CCOc1ccc2nc(O)c(CN(CCc3ccccc3)C(=O)N3CCOCC3)cc2c1 nan
3433386 44318 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
CHEMBL1517698 44318 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1cccc(NC(=O)CSc2ncnc3ccccc23)c1 nan
16018535 44459 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 1 4 4.2 CC(=O)N1CCOc2cc(S(=O)(=O)Nc3cc(C(F)(F)F)ccc3Cl)c(C)cc21 nan
CHEMBL1518991 44459 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 3 1 4 4.2 CC(=O)N1CCOc2cc(S(=O)(=O)Nc3cc(C(F)(F)F)ccc3Cl)c(C)cc21 nan
2135572 44474 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1519131 44474 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
16025796 44529 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.4 CC(NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1)c1ccccc1 nan
CHEMBL1519614 44529 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 4 5.4 CC(NC(=O)C1CCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)CC1)c1ccccc1 nan
16030429 44672 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(F)cc2)cc1 nan
CHEMBL1520828 44672 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 4 5.1 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)NCc2ccc(F)cc2)cc1 nan
15988916 44683 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 8 2 8 4.4 Cc1cc(C)c(NC(=O)Cn2c(=O)n(Cc3ccc(C(=O)NCc4ccco4)cc3)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1520905 44683 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 8 2 8 4.4 Cc1cc(C)c(NC(=O)Cn2c(=O)n(Cc3ccc(C(=O)NCc4ccco4)cc3)c(=O)c3sccc32)c(C)c1 nan
289464 44731 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 1 4.5 O=C(O)c1cc2ccccc2c2cc(Br)ccc12 nan
CHEMBL1521339 44731 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 1 1 1 4.5 O=C(O)c1cc2ccccc2c2cc(Br)ccc12 nan
2745168 44791 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 1 6 1.2 COCc1nc(S)c(C#N)cc1C(=O)OC nan
CHEMBL1521853 44791 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 1 6 1.2 COCc1nc(S)c(C#N)cc1C(=O)OC nan
689389 44837 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 6 1 5 3.4 CCN(CC)CCNc1cc(C)c(C#N)c2nc3ccccc3n12 nan
CHEMBL1522224 44837 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 6 1 5 3.4 CCN(CC)CCNc1cc(C)c(C#N)c2nc3ccccc3n12 nan
1167955 44971 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 5 5.0 O=C(CSc1nc(-c2ccc(F)cc2)nc2ccc(F)cc12)Nc1cccc(C(=O)O)c1 nan
CHEMBL1523483 44971 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 5 5.0 O=C(CSc1nc(-c2ccc(F)cc2)nc2ccc(F)cc12)Nc1cccc(C(=O)O)c1 nan
17201681 45033 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 2 2.4 O=C(C1CC(=O)N(c2ccc(Br)cc2)C1)N1CCCC1 nan
CHEMBL1524084 45033 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 2 2.4 O=C(C1CC(=O)N(c2ccc(Br)cc2)C1)N1CCCC1 nan
16018239 45077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 3 3.5 CCOc1ccc(NC(=O)N2CCOc3ccccc32)cc1 nan
CHEMBL1524566 45077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 3 3.5 CCOc1ccc(NC(=O)N2CCOc3ccccc32)cc1 nan
818605 45102 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 0 4 2.3 COc1ccc(C=O)cc1CN1C(=O)c2ccccc2C1=O nan
CHEMBL1524802 45102 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 0 4 2.3 COc1ccc(C=O)cc1CN1C(=O)c2ccccc2C1=O nan
16015121 45122 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
CHEMBL1525000 45122 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 4.0 COc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
4624396 45148 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.1 CCOc1ccc(-c2csc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)n2)cc1 nan
CHEMBL1525327 45148 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 6 4.1 CCOc1ccc(-c2csc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)n2)cc1 nan
551547 45165 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 3 4.6 O=C(NCC1CCCO1)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1525441 45165 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 1 3 4.6 O=C(NCC1CCCO1)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
2904040 45192 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 2 3 3.0 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(-c3ccccc3)cc2)cc1 nan
CHEMBL1525655 45192 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 2 3 3.0 NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(-c3ccccc3)cc2)cc1 nan
2868184 45213 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 nan
CHEMBL1525829 45213 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 nan
16018537 45250 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 1.6 CCOC(=O)C1CCCN(C(=O)CCS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)C1 nan
CHEMBL1526153 45250 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 1.6 CCOC(=O)C1CCCN(C(=O)CCS(=O)(=O)c2cc3c(cc2Cl)NC(=O)CO3)C1 nan
3151412 45384 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 8 0.7 COCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1527265 45384 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 8 0.7 COCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3ccccc3nc21 nan
3772745 45428 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 4 4.9 COc1cccc(-c2cc(C(=O)NCC3CCCO3)c3cc(Br)cc(C)c3n2)c1 nan
CHEMBL1527660 45428 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 4 4.9 COc1cccc(-c2cc(C(=O)NCC3CCCO3)c3cc(Br)cc(C)c3n2)c1 nan
1253448 45442 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
CHEMBL1527795 45442 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC1 nan
661360 45449 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 7 1.5 COc1ccc(-n2ncc3c(N4CCC(C(N)=O)CC4)ncnc32)cc1 nan
CHEMBL1527862 45449 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 7 1.5 COc1ccc(-n2ncc3c(N4CCC(C(N)=O)CC4)ncnc32)cc1 nan
1077518 45540 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 6 2.5 CCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1528629 45540 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 6 2.5 CCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3cccc(C)c3nc21 nan
16813521 45584 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 1.8 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCC4)nn23)cc1 nan
CHEMBL1529059 45584 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 1 8 1.8 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCC4)nn23)cc1 nan
54694033 45609 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 2 5 2.6 CCCn1c(=O)c(C(=O)NCc2ccco2)c(O)c2ccccc21 nan
CHEMBL1529241 45609 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 5 2 5 2.6 CCCn1c(=O)c(C(=O)NCc2ccco2)c(O)c2ccccc21 nan
625773 45776 57 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 3 4.3 O=C(O)c1cc(-c2ccc(Cl)s2)nc2ccccc12 nan
CHEMBL153072 45776 57 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 3 4.3 O=C(O)c1cc(-c2ccc(Cl)s2)nc2ccccc12 nan
3151486 45794 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 2 8 1.8 CCOCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL1530888 45794 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 2 8 1.8 CCOCCCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cccc(C)c3nc21 nan
4216259 45834 6 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 2.0 CCCCn1c(=O)[nH]c(=O)c2c1nc(Cn1ncc(Cl)c(Cl)c1=O)n2CCC nan
CHEMBL1531245 45834 6 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 2.0 CCCCn1c(=O)[nH]c(=O)c2c1nc(Cn1ncc(Cl)c(Cl)c1=O)n2CCC nan
2737056 45921 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 191 1 0 4 1.4 O=C1CC(=O)c2c1cccc2[N+](=O)[O-] nan
CHEMBL1532031 45921 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 191 1 0 4 1.4 O=C1CC(=O)c2c1cccc2[N+](=O)[O-] nan
2085635 45972 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 2 0 5 2.9 Cc1ccc2nc(Cn3cc(C(F)(F)F)cc(Cl)c3=O)cc(=O)n2c1 nan
CHEMBL1532467 45972 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 2 0 5 2.9 Cc1ccc2nc(Cn3cc(C(F)(F)F)cc(Cl)c3=O)cc(=O)n2c1 nan
3721626 46003 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 5 3.9 COc1ccc2c(c1)c1ncnc(N(C)C3CCCCC3)c1n2C nan
CHEMBL1532723 46003 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 5 3.9 COc1ccc2c(c1)c1ncnc(N(C)C3CCCCC3)c1n2C nan
3312243 46246 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4ccc(F)cc4)c3nc12 nan
CHEMBL1535016 46246 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.5 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4ccc(F)cc4)c3nc12 nan
135403580 46347 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 7 4.6 N#Cc1c(O)nc(SCC(=O)Nc2ccc(OC(F)(F)Cl)cc2)nc1-c1ccccc1 nan
CHEMBL1536174 46347 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 7 4.6 N#Cc1c(O)nc(SCC(=O)Nc2ccc(OC(F)(F)Cl)cc2)nc1-c1ccccc1 nan
5310128 46363 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1ccc2nnc(-c3ccncc3)n2n1)NCC1CCCO1 nan
CHEMBL1536319 46363 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 8 1.6 O=C(CSc1ccc2nnc(-c3ccncc3)n2n1)NCC1CCCO1 nan
20878456 46396 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 8 2.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2ccccc23)cc1 nan
CHEMBL1536657 46396 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 8 2.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2ccccc23)cc1 nan
5059230 46407 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 2.5 N#CC1=C([C-](C#N)C#N)NC(O)(C2CC2)C([n+]2ccccc2)C1c1ccccc1F nan
CHEMBL1536738 46407 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 2.5 N#CC1=C([C-](C#N)C#N)NC(O)(C2CC2)C([n+]2ccccc2)C1c1ccccc1F nan
5235682 46476 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)no1 nan
CHEMBL1537295 46476 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)no1 nan
7190492 46647 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1538682 46647 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 8 3.3 CCOc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
3220383 46721 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 3.3 CC(C)CC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
CHEMBL1539378 46721 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 6 3.3 CC(C)CC(OC(=O)c1nsc(Cl)c1Cl)C(=O)NCC1CCCO1 nan
6133031 46749 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 7 2.4 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1539594 46749 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 7 2.4 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccccc1)c1ccc2c(c1)OCCO2 nan
1567287 46854 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 6 -1.0 CN1C(=O)C(=CNCCN2CCOCC2)C(=O)N(C)C1=S nan
CHEMBL1540479 46854 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 6 -1.0 CN1C(=O)C(=CNCCN2CCOCC2)C(=O)N(C)C1=S nan
2983027 46871 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 1.8 O=C(NCc1cccnc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
CHEMBL1540590 46871 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 1.8 O=C(NCc1cccnc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1 nan
2431987 46896 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 1 5 3.0 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
CHEMBL1540855 46896 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 1 5 3.0 COCCCn1c(=S)[nH]c2sc3c(c2c1=O)CCCC3 nan
3833515 46921 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 7 5.1 C=CCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1541029 46921 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 7 5.1 C=CCOc1cccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
6273159 47008 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
CHEMBL1541682 47008 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2ccncc2)c1 nan
659524 47195 7 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 1 0 3 4.1 Brc1cc(Br)c2ncnc(N3CCCCC3)c2c1 nan
CHEMBL1543331 47195 7 None -3 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 1 0 3 4.1 Brc1cc(Br)c2ncnc(N3CCCCC3)c2c1 nan
16194876 47441 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(OC)c(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
CHEMBL1545182 47441 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 9 2.9 COc1ccc(OC)c(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)c1 nan
2997987 47472 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.0 Cc1sc2ncnc(OCC(=O)NCC3CCCO3)c2c1C nan
CHEMBL1545423 47472 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.0 Cc1sc2ncnc(OCC(=O)NCC3CCCO3)c2c1C nan
16188698 47562 0 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 2 4.2 Cc1ccccc1CC1(CO)CCCN(C(=O)c2cc(Cl)ccc2F)C1 nan
CHEMBL1546168 47562 0 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 2 4.2 Cc1ccccc1CC1(CO)CCCN(C(=O)c2cc(Cl)ccc2F)C1 nan
5389436 47683 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 3.8 COc1cccc(C2C(C(=O)c3ccc(OC)c(OC)c3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1547272 47683 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 8 3.8 COc1cccc(C2C(C(=O)c3ccc(OC)c(OC)c3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
16437942 48011 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 9 2.2 CCCS(=O)(=O)c1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)n1 nan
CHEMBL1550174 48011 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 9 2.2 CCCS(=O)(=O)c1ncc(Cl)c(C(=O)Nc2ccc(S(=O)(=O)Nc3ncccn3)cc2)n1 nan
3579665 48056 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 7 2.3 COC(=O)c1c(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c1CCN(C(C)=O)C2 nan
CHEMBL1550602 48056 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 7 2.3 COC(=O)c1c(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c1CCN(C(C)=O)C2 nan
5308895 48111 1 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 0 5 4.0 N#CC1=C2SCN(Cc3ccccc3)CN2C(=O)CC1c1cccs1 nan
CHEMBL1551015 48111 1 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 0 5 4.0 N#CC1=C2SCN(Cc3ccccc3)CN2C(=O)CC1c1cccs1 nan
16031535 48151 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)s2)cc1 nan
CHEMBL1551622 48151 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)s2)cc1 nan
16015115 48160 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.3 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
CHEMBL1551830 48160 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.3 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1 nan
15989679 48216 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1OC nan
CHEMBL1552471 48216 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 9 1 9 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1OC nan
16030838 48235 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
53229832 48235 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
CHEMBL1552774 48235 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 2 8 2.3 COc1ccc(-c2cc3ccc(O)c(CN4CCN(CCO)CC4)c3oc2=O)cc1OC nan
1004132 48269 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 2 4 4.9 Cc1ccc(CNC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1 nan
CHEMBL1553209 48269 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 2 4 4.9 Cc1ccc(CNC(=O)c2sc3nc(-c4ccc(F)cc4)ccc3c2N)cc1 nan
15988065 48272 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 2 1 8 3.6 O=c1c2cc3c(cc2nc2sc(Nc4ccc(F)c(Cl)c4)nn12)OCO3 nan
CHEMBL1553232 48272 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 2 1 8 3.6 O=c1c2cc3c(cc2nc2sc(Nc4ccc(F)c(Cl)c4)nn12)OCO3 nan
16008431 48279 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 5 4.1 O=C(c1ccc(F)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCO3 nan
CHEMBL1553329 48279 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 5 4.1 O=C(c1ccc(F)cc1)c1cn(Cc2ccccc2)c2cc3c(cc2c1=O)OCO3 nan
16018243 48282 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 1 1 2 4.1 Cc1c(Cl)cccc1NC(=O)N1CCOc2ccccc21 nan
CHEMBL1553372 48282 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 1 1 2 4.1 Cc1c(Cl)cccc1NC(=O)N1CCOc2ccccc21 nan
1364295 48312 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 2 5 5.3 O=C(COc1ccc(Cl)cc1)Nc1ccc(O)c(-c2nc3ccccc3s2)c1 nan
CHEMBL1553843 48312 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 2 5 5.3 O=C(COc1ccc(Cl)cc1)Nc1ccc(O)c(-c2nc3ccccc3s2)c1 nan
5302298 48322 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 2 2 5 5.5 Nc1c(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)sc2nc3c(cc12)N1CCC3CC1 nan
CHEMBL1554006 48322 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 2 2 5 5.5 Nc1c(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)sc2nc3c(cc12)N1CCC3CC1 nan
16018784 48336 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 1 8 3.8 CCc1nnc(SCC(=O)Nc2ccc(OC)c(OC)c2)c2cc3occc3n12 nan
CHEMBL1554189 48336 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 7 1 8 3.8 CCc1nnc(SCC(=O)Nc2ccc(OC)c(OC)c2)c2cc3occc3n12 nan
16018201 48377 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 3 3.8 Cc1ccc2c(c1)N(C(=O)N1CCC(C(=O)NCCc3ccccc3)CC1)CC(C)O2 nan
CHEMBL1554848 48377 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 3 3.8 Cc1ccc2c(c1)N(C(=O)N1CCC(C(=O)NCCc3ccccc3)CC1)CC(C)O2 nan
3151378 48453 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 2 7 2.9 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCCC4)c3nc12 nan
CHEMBL1555780 48453 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 2 7 2.9 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(C4CCCCC4)c3nc12 nan
16019891 48655 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 0 9 5.1 CCC(=O)Oc1cc(C(C)(C)C)cc2cc(-c3nc(-c4ccc(OC)cc4OC)no3)c(=O)oc12 nan
CHEMBL1557596 48655 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 0 9 5.1 CCC(=O)Oc1cc(C(C)(C)C)cc2cc(-c3nc(-c4ccc(OC)cc4OC)no3)c(=O)oc12 nan
3239255 48745 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 3.8 COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC nan
CHEMBL1558431 48745 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 3.8 COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC nan
662047 48908 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 7 3.8 COc1cccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1559829 48908 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 7 3.8 COc1cccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
2612492 49061 5 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 7 3.9 Cc1nc(SCC(=O)Nc2cc(C)on2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1561287 49061 5 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 7 3.9 Cc1nc(SCC(=O)Nc2cc(C)on2)c2c3c(sc2n1)CCCC3 nan
670483 49071 38 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 2 1 4 3.4 Fc1cccc(-c2nnc(S)n2-c2ccccc2)c1 nan
CHEMBL1561393 49071 38 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 2 1 4 3.4 Fc1cccc(-c2nnc(S)n2-c2ccccc2)c1 nan
16025728 49178 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 6 5.8 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3C)s1)C2 nan
CHEMBL1562331 49178 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 1 6 5.8 COc1cccc2c1Oc1ncccc1N(c1ccc(C(=O)NCc3ccccc3C)s1)C2 nan
135788252 49225 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 8 3.1 COC(=O)c1cc(-c2ccc(OC)cc2F)nc2nc(SC)nc(O)c12 nan
CHEMBL1562765 49225 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 8 3.1 COC(=O)c1cc(-c2ccc(OC)cc2F)nc2nc(SC)nc(O)c12 nan
20956964 49226 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 9 0.6 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)CC1 nan
CHEMBL1562772 49226 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 9 0.6 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)CC1 nan
15988783 49271 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 7 1 10 2.8 Cc1sc2ncn(CC(=O)Nc3ccc(C(C)C)cc3)c(=O)c2c1S(=O)(=O)N1CCN(c2ncccn2)CC1 nan
CHEMBL1563146 49271 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 7 1 10 2.8 Cc1sc2ncn(CC(=O)Nc3ccc(C(C)C)cc3)c(=O)c2c1S(=O)(=O)N1CCN(c2ncccn2)CC1 nan
20923169 49328 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 0 6 2.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)CC(C)C1 nan
CHEMBL1563711 49328 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 0 6 2.6 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CC(C)CC(C)C1 nan
16009570 49464 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cn2c(=O)cc(COc3cccc(NC(=O)c4ccccc4C)c3)nc2s1 nan
CHEMBL1564898 49464 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cn2c(=O)cc(COc3cccc(NC(=O)c4ccccc4C)c3)nc2s1 nan
22517528 49476 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 3.0 CC1CCN(S(=O)(=O)c2nnc(NC(=O)c3ccccc3Br)s2)CC1 nan
CHEMBL1564984 49476 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 4 1 6 3.0 CC1CCN(S(=O)(=O)c2nnc(NC(=O)c3ccccc3Br)s2)CC1 nan
16001900 49918 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 8 2 8 3.6 COc1ccc(CCNc2nc(S)nc3cc(OC)c(OC)cc23)cc1OC nan
CHEMBL1568426 49918 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 8 2 8 3.6 COc1ccc(CCNc2nc(S)nc3cc(OC)c(OC)cc23)cc1OC nan
2952518 49987 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 571 9 3 9 6.0 CCOc1ccccc1NC(=O)CSC1=C(C#N)C(c2ccco2)C(C(=O)Nc2nc3ccccc3s2)=C(C)N1 nan
CHEMBL1569028 49987 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 571 9 3 9 6.0 CCOc1ccccc1NC(=O)CSC1=C(C#N)C(c2ccco2)C(C(=O)Nc2nc3ccccc3s2)=C(C)N1 nan
18562928 50001 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 8 1 8 2.2 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCCC4)nn23)cc1 nan
CHEMBL1569159 50001 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 8 1 8 2.2 COc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)N4CCCCC4)nn23)cc1 nan
3152775 50226 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3ccc(O)cc3)sc2c1 nan
CHEMBL1571071 50226 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 4 2 7 5.0 Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccc(C)o4)C3c3ccc(O)cc3)sc2c1 nan
3564285 50519 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
5036767 50519 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
CHEMBL1573867 50519 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 5 4.3 CN(C)CCN1C(=O)C(O)=C(C(=O)c2cc3ccccc3o2)C1c1cccc(Br)c1 nan
1325969 50531 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 0 7 5.3 COc1cc(-c2nnc(COc3ccc4cc(Br)ccc4c3)o2)cc(OC)c1OC nan
CHEMBL1574014 50531 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 0 7 5.3 COc1cc(-c2nnc(COc3ccc4cc(Br)ccc4c3)o2)cc(OC)c1OC nan
3613213 50696 11 None -1000 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 2 3 4.6 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(F)cc1 nan
CHEMBL1575774 50696 11 None -1000 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 2 3 4.6 O=C(O)CC(NC(=O)c1sc2ccccc2c1Cl)c1ccc(F)cc1 nan
2352763 50724 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 1 4 2.6 NC(=O)COC(=O)CSc1cccc2cccc(Cl)c12 nan
CHEMBL1576037 50724 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 5 1 4 2.6 NC(=O)COC(=O)CSc1cccc2cccc(Cl)c12 nan
135433192 51016 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 4 3.8 Oc1nc(SCc2ccccc2F)nc2ccccc12 nan
CHEMBL1578484 51016 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 4 3.8 Oc1nc(SCc2ccccc2F)nc2ccccc12 nan
18107118 51034 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 5 2.9 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccccn1 nan
CHEMBL1578588 51034 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 5 2.9 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccccn1 nan
1838209 51080 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 2 8 1.2 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NCc1ccco1 nan
CHEMBL1578976 51080 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 2 8 1.2 N#C/C(=C\c1c(N2CCC(C(N)=O)CC2)nc2ccccn2c1=O)C(=O)NCc1ccco1 nan
3802907 51147 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
4542697 51147 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
CHEMBL1579576 51147 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 1 6 4.1 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Br)c1)c1cc2ccccc2o1 nan
16196197 51159 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
3610394 51159 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
CHEMBL1579745 51159 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 4 6.4 Cc1cc(/C(O)=C(/C([S-])=Nc2ccc(F)cc2)[n+]2ccccc2)c(C)n1Cc1ccccc1Cl nan
2357568 51177 6 None -5 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 6 4.7 O=C(CSc1nnc(-c2cccs2)n1-c1ccccc1)Nc1ccccc1 nan
CHEMBL1579942 51177 6 None -5 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 6 4.7 O=C(CSc1nnc(-c2cccs2)n1-c1ccccc1)Nc1ccccc1 nan
4831734 51207 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 7 1 6 3.8 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2c3c(nc4ccccc24)CCC3)c1 nan
CHEMBL1580173 51207 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 7 1 6 3.8 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2c3c(nc4ccccc24)CCC3)c1 nan
1476967 51239 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 0 6 2.0 c1cn(-c2ccc(-c3ccnc4ncnn34)cc2)cn1 nan
CHEMBL1580435 51239 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 262 2 0 6 2.0 c1cn(-c2ccc(-c3ccnc4ncnn34)cc2)cn1 nan
7190795 51252 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 0 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)c1ccccc1 nan
CHEMBL1580576 51252 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 0 7 3.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)c1ccccc1 nan
16194926 51327 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 2.5 Cc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1581174 51327 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 2.5 Cc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
3357076 51404 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 5 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccncc2)c1 nan
CHEMBL1581844 51404 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 5 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2)c(NC(=O)c2ccncc2)c1 nan
3151315 51558 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.9 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1583158 51558 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.9 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CC4CCCO4)c3nc12 nan
3721854 51676 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 2 1 7 2.1 Nc1c(C(=O)N2CCOCC2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1584034 51676 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 2 1 7 2.1 Nc1c(C(=O)N2CCOCC2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
3911608 51784 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.5 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
CHEMBL1584955 51784 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.5 Cc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
7207569 51963 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 1 7 1.8 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccccc1 nan
CHEMBL1586420 51963 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 7 1 7 1.8 O=C(NCCc1nnc2ccc(SCC(=O)N3CCCC3)nn12)c1ccccc1 nan
7190486 52061 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1587249 52061 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 8 2.9 COc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
5225306 52097 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.9 CC1CCCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1587533 52097 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.9 CC1CCCCN1C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
4975167 52110 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 7 1 5 3.1 CCCc1cc(=O)oc2c(C)c(OCC(=O)NCc3ccccn3)ccc12 nan
CHEMBL1587597 52110 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 7 1 5 3.1 CCCc1cc(=O)oc2c(C)c(OCC(=O)NCc3ccccn3)ccc12 nan
5236958 52291 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 2.7 CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)CSc2cccc[n+]2[O-])c1 nan
CHEMBL1589189 52291 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 8 1 5 2.7 CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)CSc2cccc[n+]2[O-])c1 nan
16022898 52376 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 7 1 6 2.7 CCOCCCNc1nc2ccccc2n2c(CC)nnc12 nan
CHEMBL1589922 52376 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 7 1 6 2.7 CCOCCCNc1nc2ccccc2n2c(CC)nnc12 nan
16009827 52387 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1OC nan
CHEMBL1590063 52387 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1OC nan
1391194 52457 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
1391195 52457 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
CHEMBL1590944 52457 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 2 4 3.9 O=C(O)CCNc1nc(-c2ccccc2)c2cc(Br)ccc2n1 nan
18572144 52480 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 2 6 2.6 Cn1c(SCC(=O)NCCc2ccccc2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
CHEMBL1591283 52480 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 8 2 6 2.6 Cn1c(SCC(=O)NCCc2ccccc2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
20903635 52504 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 0 9 1.9 CCCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
CHEMBL1591509 52504 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 0 9 1.9 CCCN1CCN(C(=O)CCc2nnc3ccc(N4CCN(c5cccc(OC)c5)CC4)nn23)CC1 nan
16012276 52527 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.3 Cc1cc(C)n2nc(CNC(=O)c3ccc(Cl)cc3)nc2n1 nan
CHEMBL1591819 52527 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 2.3 Cc1cc(C)n2nc(CNC(=O)c3ccc(Cl)cc3)nc2n1 nan
5303336 52561 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 4.2 CCOc1ccc(-c2oc3cc(Cl)ccc3c(=O)c2O)cc1OC nan
CHEMBL1592283 52561 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 4.2 CCOc1ccc(-c2oc3cc(Cl)ccc3c(=O)c2O)cc1OC nan
2790635 52671 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 2 4 4.1 Cc1ccc(OCCCC(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)cc1 nan
CHEMBL1593935 52671 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 2 4 4.1 Cc1ccc(OCCCC(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)cc1 nan
3476583 52855 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1595488 52855 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.8 Cc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
1958370 52873 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 2.5 COCCNS(=O)(=O)c1cc(-c2nn3c(C)nnc3c3ccccc23)ccc1C nan
CHEMBL1595653 52873 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 2.5 COCCNS(=O)(=O)c1cc(-c2nn3c(C)nnc3c3ccccc23)ccc1C nan
4601439 53047 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 2 7 3.9 COc1cccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c1 nan
CHEMBL1597228 53047 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 2 7 3.9 COc1cccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c1 nan
4151069 53260 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 10 0.6 COC(=O)c1cc(NS(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)cc(C(=O)OC)c1 nan
CHEMBL1599214 53260 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 10 0.6 COC(=O)c1cc(NS(=O)(=O)c2ccc3c(c2)c(=O)n(C)c(=O)n3C)cc(C(=O)OC)c1 nan
2890665 53332 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 3 1 3 3.6 CC(=O)C1=C(O)C(=O)N(c2ccc(F)cc2)C1c1ccc(C)cc1 nan
CHEMBL1599834 53332 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 3 1 3 3.6 CC(=O)C1=C(O)C(=O)N(c2ccc(F)cc2)C1c1ccc(C)cc1 nan
16020305 53650 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 12 1 6 4.3 CCCN(CCC)C(=O)Cn1c(=O)n(-c2ccc(CC)cc2)c(=O)c2ccc(C(=O)NCCc3ccccc3)cc21 nan
CHEMBL1602912 53650 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 554 12 1 6 4.3 CCCN(CCC)C(=O)Cn1c(=O)n(-c2ccc(CC)cc2)c(=O)c2ccc(C(=O)NCCc3ccccc3)cc21 nan
910705 53737 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 2 0 4 2.4 O=[N+]([O-])c1ccc(-c2cn3c(n2)CCC3)cc1 nan
CHEMBL1603668 53737 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 2 0 4 2.4 O=[N+]([O-])c1ccc(-c2cn3c(n2)CCC3)cc1 nan
1146176 53886 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 0 4 4.7 CC1CCN(C(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)n2)CC1 nan
CHEMBL1604923 53886 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 0 4 4.7 CC1CCN(C(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)n2)CC1 nan
16019480 53976 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 0 9 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCN(CC)CC2)c2sccc23)cc1 nan
CHEMBL1605620 53976 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 0 9 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCN(CC)CC2)c2sccc23)cc1 nan
1410148 54091 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.5 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccnc4)nc3c2)cc1 nan
CHEMBL1606536 54091 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.5 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccnc4)nc3c2)cc1 nan
2918495 54123 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 8 2.5 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1OC nan
CHEMBL1606762 54123 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 1 8 2.5 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1OC nan
5730347 54173 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 4 0 4 3.9 CCC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
CHEMBL1607132 54173 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 4 0 4 3.9 CCC(=O)c1ccc(/C=C/c2nc3ccccc3n2C)o1 nan
4426797 54257 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 10 -0.6 Cn1c(=O)c2c(nc(CN3CCN(C(=O)c4ccco4)CC3)n2CCCO)n(C)c1=O nan
CHEMBL1607800 54257 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 10 -0.6 Cn1c(=O)c2c(nc(CN3CCN(C(=O)c4ccco4)CC3)n2CCCO)n(C)c1=O nan
1325691 54290 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 1 1 7 3.2 Sc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1608119 54290 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 1 1 7 3.2 Sc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CCCC3 nan
2966904 54294 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 7 2 7 3.4 CC(=O)c1sc2nc(SCC(=O)NCCc3ccccc3)nc(O)c2c1C nan
CHEMBL1608140 54294 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 7 2 7 3.4 CC(=O)c1sc2nc(SCC(=O)NCCc3ccccc3)nc(O)c2c1C nan
16406841 54300 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 6 3.1 Cc1c(Br)c(=O)oc2cc(OCC(=O)N3C[C@@H]4C[C@H](C3)Cn3c4cccc3=O)ccc12 nan
CHEMBL1608190 54300 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 6 3.1 Cc1c(Br)c(=O)oc2cc(OCC(=O)N3C[C@@H]4C[C@H](C3)Cn3c4cccc3=O)ccc12 nan
54686430 54365 31 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 2 4 1.8 CCCNC(=O)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
CHEMBL1608771 54365 31 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 2 4 1.8 CCCNC(=O)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
6107794 54423 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 7 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c(OC)c1 nan
CHEMBL1609202 54423 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 7 4.2 COc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c(OC)c1 nan
2576098 54455 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 2.7 Cc1sc2ncnc(NCCCN3CCCC3=O)c2c1C nan
CHEMBL1609414 54455 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 5 1 5 2.7 Cc1sc2ncnc(NCCCN3CCCC3=O)c2c1C nan
3641030 54511 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 3 5.1 CC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc1 nan
CHEMBL1609950 54511 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 3 5.1 CC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc1 nan
2868074 54529 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccc(Br)cc1 nan
CHEMBL1610073 54529 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccc(Br)cc1 nan
2790804 54640 18 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 6 3.8 O=[N+]([O-])c1ccc(-c2nc(NCC3CCCO3)c3ccccc3n2)cc1 nan
CHEMBL1611050 54640 18 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 6 3.8 O=[N+]([O-])c1ccc(-c2nc(NCC3CCCO3)c3ccccc3n2)cc1 nan
2934073 54891 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccc(Cl)c1)c1ccco1 nan
CHEMBL1613356 54891 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 5 3.7 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccc(Cl)c1)c1ccco1 nan
4581262 55327 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
CHEMBL1377318 55327 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
CHEMBL1618739 55327 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 4.4 CC1CCN(CCCn2c(=S)[nH]c3c(sc4ccccc43)c2=O)CC1 nan
1099157 55353 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
CHEMBL1389219 55353 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
CHEMBL1618947 55353 12 None -3 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 4 4.4 O=C(CN1CCCCC1)Nc1c2c(nc3ccccc13)N(c1ccccc1)CC2 nan
4055296 55480 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
CHEMBL1420869 55480 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
CHEMBL1620041 55480 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 5.8 O=[N+]([O-])c1cccc(-c2cc3sc4ccccc4[n+]3cc2-c2cccc([N+](=O)[O-])c2)c1 nan
655842 55628 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
CHEMBL1466356 55628 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
CHEMBL1621365 55628 11 None -12 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 5 3.0 CSCCC(Nc1ncnc2ccc(Br)cc12)C(=O)O nan
3848238 56004 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
CHEMBL1548688 56004 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
CHEMBL1624498 56004 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 5 5.5 N#Cc1c(SC(C(=O)O)c2ccccc2)nc2c(c1-c1cccs1)CCCC2 nan
3589783 56017 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
CHEMBL1566042 56017 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
CHEMBL1624662 56017 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 2 2 6 5.1 CC1(C)CC2=NC3=C(C(=O)c4ccccc43)C(c3cc([N+](=O)[O-])ccc3O)C2=C(O)C1 nan
9560158 72198 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
CHEMBL1980603 72198 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1cccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 nan
9624156 72272 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 4.4 N#CCC(=O)N/N=C/c1ccc(N2N=C(c3ccccc3)CC2c2ccccc2)cc1 nan
CHEMBL1982521 72272 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 4.4 N#CCC(=O)N/N=C/c1ccc(N2N=C(c3ccccc3)CC2c2ccccc2)cc1 nan
1995859 72803 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 7 1.3 COCCCn1/c(=N/C(C)=O)c(C#N)cc2c(=O)n3cccc(C)c3nc21 nan
CHEMBL2000901 72803 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 7 1.3 COCCCn1/c(=N/C(C)=O)c(C#N)cc2c(=O)n3cccc(C)c3nc21 nan
65599 105422 45 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL311948 105422 45 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 5 0 7 0.2 CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C nan
2864416 106886 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 1.6 Cc1[nH]n(-c2ccc([N+](=O)[O-])cc2)c(=O)c1/C=N/CCN1CCN(C(=O)C(C)C)CC1 nan
CHEMBL3145301 106886 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 7 1.6 Cc1[nH]n(-c2ccc([N+](=O)[O-])cc2)c(=O)c1/C=N/CCN1CCN(C(=O)C(C)C)CC1 nan
5935610 107607 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 1 1 3 3.9 CCn1c2c(c3cc(Br)ccc31)CCC/C2=N\O nan
CHEMBL3189713 107607 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 1 1 3 3.9 CCn1c2c(c3cc(Br)ccc31)CCC/C2=N\O nan
6279969 107884 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 0 6 2.1 CN(C)/C=N/c1nc2nccc(-c3cccs3)n2n1 nan
CHEMBL3192852 107884 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 0 6 2.1 CN(C)/C=N/c1nc2nccc(-c3cccs3)n2n1 nan
6860035 108116 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 8 3.0 COc1ccc(OC)c(/C=N/n2c(S)nnc2COc2ccccc2)c1 nan
CHEMBL3195667 108116 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 7 1 8 3.0 COc1ccc(OC)c(/C=N/n2c(S)nnc2COc2ccccc2)c1 nan
135467322 108697 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 6 4.3 COC(=O)/C(Nc1ccccc1)=C(\C(=O)C(=O)N(C)c1ccccc1)C(=O)c1ccc(Cl)cc1 nan
CHEMBL3208147 108697 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 8 1 6 4.3 COC(=O)/C(Nc1ccccc1)=C(\C(=O)C(=O)N(C)c1ccccc1)C(=O)c1ccc(Cl)cc1 nan
2805193 108810 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 5 1 7 2.6 CCO/C(O)=C(C#N)/C=N/c1ccsc1C(=O)OC nan
CHEMBL3209558 108810 4 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 5 1 7 2.6 CCO/C(O)=C(C#N)/C=N/c1ccsc1C(=O)OC nan
5867179 109018 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.1 C/C(N)=C(/C#N)C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL3212349 109018 3 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.1 C/C(N)=C(/C#N)C(=O)COC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
3221537 112619 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
CHEMBL3209727 112619 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
CHEMBL3302425 112619 6 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 0 5 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\C)S3 nan
264006 178563 13 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 4 9 -1.0 C=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
CHEMBL46703 178563 13 None 1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 4 9 -1.0 C=CCNc1ncnc2c1ncn2C1OC(CO)C(O)C1O nan
833435 197670 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 3 4 2.9 Cc1sc(NC(=S)NC(=O)C2CCCCC2)c(C(N)=O)c1C nan
CHEMBL571065 197670 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 3 4 2.9 Cc1sc(NC(=S)NC(=O)C2CCCCC2)c(C(N)=O)c1C nan
22334103 200909 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 9 2 8 1.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1Cl nan
CHEMBL601585 200909 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 9 2 8 1.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCCCN3CCOCC3)c3ccccc3c2=O)cc1Cl nan
4167655 28250 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.3 Brc1ccc(-c2nnc3sc(CNC4CCCC4)cn23)cc1 nan
CHEMBL1374064 28250 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.3 Brc1ccc(-c2nnc3sc(CNC4CCCC4)cn23)cc1 nan
16018920 28485 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 6 4.8 CCc1nnc(SCC(=O)Nc2ccc(F)cc2F)c2cc3sc(C)cc3n12 nan
CHEMBL1375688 28485 6 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 6 4.8 CCc1nnc(SCC(=O)Nc2ccc(F)cc2F)c2cc3sc(C)cc3n12 nan
3348974 39192 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 11 0.5 CCc1nnc(NC(=O)CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1469832 39192 10 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 11 0.5 CCc1nnc(NC(=O)CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)s1 nan
4351083 47167 8 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 8 3.0 O=C(NN1C(=O)c2ccccc2NC1c1ccc([N+](=O)[O-])o1)c1ccc([N+](=O)[O-])cc1 nan
CHEMBL1543122 47167 8 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 2 8 3.0 O=C(NN1C(=O)c2ccccc2NC1c1ccc([N+](=O)[O-])o1)c1ccc([N+](=O)[O-])cc1 nan
3241486 49924 6 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 6 4.2 COc1ccc(C(=O)Nc2ccc(N3CCN(c4ccc(OC)cc4)CC3)c(C#N)c2)cc1 nan
CHEMBL1568468 49924 6 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 6 4.2 COc1ccc(C(=O)Nc2ccc(N3CCN(c4ccc(OC)cc4)CC3)c(C#N)c2)cc1 nan
1261644 50080 10 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 1 4 4.7 O=C(Nc1ccncc1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
CHEMBL1569872 50080 10 None 1 2 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 1 4 4.7 O=C(Nc1ccncc1)c1cc(-c2ccccn2)nc2ccc(Br)cc12 nan
759120 52563 34 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1592299 52563 34 None - 1 Human 5.6 pPotency = 5.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
16010305 7673 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 3.2 COCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccc(Cl)cc12 nan
CHEMBL1088575 7673 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 7 1 8 3.2 COCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccc(Cl)cc12 nan
16019548 10882 10 None -23 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 8 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(Cl)cc1)c1sccc12 nan
CHEMBL1172597 10882 10 None -23 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 8 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccc(Cl)cc1)c1sccc12 nan
16019364 10957 6 None -53 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 8 4.5 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1C nan
CHEMBL1173283 10957 6 None -53 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 8 4.5 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1C nan
5721990 14826 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 0 2 4.5 CN(C)c1ccc(/C=C/c2ccc3ccccc3n2)cc1 nan
CHEMBL120734 14826 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 0 2 4.5 CN(C)c1ccc(/C=C/c2ccc3ccccc3n2)cc1 nan
3565 19372 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
CHEMBL129177 19372 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
CHEMBL1473205 19372 51 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 200 0 2 2 2.2 CC1=NCCc2c1[nH]c1cc(O)ccc21 nan
2803232 19519 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 2 4.3 S=C(Nc1ccccc1)Nc1ccccc1-n1cccc1 nan
CHEMBL1299459 19519 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 2 2 4.3 S=C(Nc1ccccc1)Nc1ccccc1-n1cccc1 nan
1305405 19675 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 3 4 4.4 O=C(O)c1ccccc1NC(=S)NC(=O)c1sc2ccccc2c1Cl nan
CHEMBL1300720 19675 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 3 4 4.4 O=C(O)c1ccccc1NC(=S)NC(=O)c1sc2ccccc2c1Cl nan
24790327 19710 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 5 4.4 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cnn(C(C)C)c4)C3)ccc2c1 nan
CHEMBL1300972 19710 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 5 4.4 COc1ccc2cc(C(=O)C3CCCN(C(=O)c4cnn(C(C)C)c4)C3)ccc2c1 nan
5826640 19778 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 7 4.1 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1301431 19778 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 7 4.1 CCCCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
2410711 19797 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 3.5 CCOc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
CHEMBL1301615 19797 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 3.5 CCOc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
5918716 19866 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 7 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NC)CC1 nan
CHEMBL1302267 19866 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 7 0.8 CCN1CCN(c2nc3c(C)cccn3c(=O)c2/C=C(\C#N)C(=O)NC)CC1 nan
910973 19993 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 1 2 6 1.6 N#CC(C#N)=C1NC(N)=C(C#N)C(c2ccccc2)=C1C#N nan
CHEMBL1303255 19993 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 1 2 6 1.6 N#CC(C#N)=C1NC(N)=C(C#N)C(c2ccccc2)=C1C#N nan
2472728 20167 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 7 2.7 Cc1sc2ncnc(SCC(=O)NC(=O)c3cccn3C)c2c1C nan
CHEMBL1304667 20167 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 7 2.7 Cc1sc2ncnc(SCC(=O)NC(=O)c3cccn3C)c2c1C nan
3544771 20189 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 0 9 3.2 O=c1c2sccc2nc(SCc2cc(=O)n3ccccc3n2)n1Cc1ccccn1 nan
CHEMBL1304859 20189 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 0 9 3.2 O=c1c2sccc2nc(SCc2cc(=O)n3ccccc3n2)n1Cc1ccccn1 nan
7295015 20329 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.6 CSc1ccccc1-c1nnc(NC(=O)Cc2ccccc2)o1 nan
CHEMBL1305973 20329 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.6 CSc1ccccc1-c1nnc(NC(=O)Cc2ccccc2)o1 nan
654420 20332 5 None -28 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 5 0 5 2.8 CCOC(=O)CSc1nc(CC)nc2ccccc12 nan
CHEMBL1305990 20332 5 None -28 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 5 0 5 2.8 CCOC(=O)CSc1nc(CC)nc2ccccc12 nan
4021231 20342 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.7 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc(F)cc4)c(=N)n(CC4CCCO4)c3nc12 nan
CHEMBL1306067 20342 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 2 7 2.7 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccc(F)cc4)c(=N)n(CC4CCCO4)c3nc12 nan
833786 20393 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 3 1 4 4.2 Sc1nc(SCc2ccccc2)nc2ccccc12 nan
CHEMBL1306480 20393 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 3 1 4 4.2 Sc1nc(SCc2ccccc2)nc2ccccc12 nan
865618 20404 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 0 4 3.6 CN(C)c1ccc(-c2nnc(-c3ccccc3F)o2)cc1 nan
CHEMBL1306590 20404 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 0 4 3.6 CN(C)c1ccc(-c2nnc(-c3ccccc3F)o2)cc1 nan
6078291 20511 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1307444 20511 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 6 4.6 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2Cc2cccnc2)c1 nan
2820469 20590 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 3.4 CSc1sc(C(=O)NCC2CC2)c2c1S(=O)(=O)N(C)c1ccccc1-2 nan
CHEMBL1308054 20590 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 3.4 CSc1sc(C(=O)NCC2CC2)c2c1S(=O)(=O)N(C)c1ccccc1-2 nan
5012705 20600 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 9 2 6 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCCc1ccccc1 nan
CHEMBL1308124 20600 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 9 2 6 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCCc1ccccc1 nan
1201985 20750 9 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 6 3.8 O=C(CSc1nc2ccccc2nc1SCC(=O)N1CCCCC1)N1CCCCC1 nan
CHEMBL1309335 20750 9 None -2 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 6 3.8 O=C(CSc1nc2ccccc2nc1SCC(=O)N1CCCCC1)N1CCCCC1 nan
24891893 20758 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 9 -0.0 CCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1309394 20758 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 9 -0.0 CCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
1596915 20772 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 7 4.6 Cc1csc(NC(=O)c2sc3nc(-c4cccs4)ccc3c2N)n1 nan
CHEMBL1309478 20772 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 7 4.6 Cc1csc(NC(=O)c2sc3nc(-c4cccs4)ccc3c2N)n1 nan
3236246 20854 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 7 1 8 2.8 CCC(Sc1ccc2nnc(-c3ccc(OC)c(OC)c3)n2n1)C(=O)O nan
CHEMBL1310295 20854 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 7 1 8 2.8 CCC(Sc1ccc2nnc(-c3ccc(OC)c(OC)c3)n2n1)C(=O)O nan
4881170 20961 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 0 6 3.0 Cc1nc(SC2CCOC2=O)c2c(C)c(C)sc2n1 nan
CHEMBL1311178 20961 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 0 6 3.0 Cc1nc(SC2CCOC2=O)c2c(C)c(C)sc2n1 nan
5813760 21007 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccc(Br)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1311567 21007 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 5 1 6 4.4 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccc(Br)cc1)c1ccc2c(c1)OCCO2 nan
3682235 21082 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
CHEMBL1312109 21082 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 7 3.7 COc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)c1 nan
3588555 21161 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 580 5 1 8 3.8 Cc1cc(Br)ccc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
CHEMBL1312634 21161 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 580 5 1 8 3.8 Cc1cc(Br)ccc1NC(=O)c1sc2ncn(CC(=O)N3CCN(c4ccccn4)CC3)c(=O)c2c1C nan
2332949 21172 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 2 5 4.7 Cc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2C)o1 nan
CHEMBL1312698 21172 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 2 5 4.7 Cc1ccc(-c2c(C#N)c(S)nc(C)c2C(=O)Nc2ccccc2C)o1 nan
20957089 21181 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 9 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCc4ccco4)nn23)CC1 nan
CHEMBL1312760 21181 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 9 2.1 CCOC(=O)C1CCN(C(=O)CCc2nnc3ccc(NCc4ccco4)nn23)CC1 nan
7064857 21473 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 5.1 CCc1cccc(C)c1Nc1c(-c2ccc(N(C)C)cc2)nc2cnccn12 nan
CHEMBL1315626 21473 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 5 5.1 CCc1cccc(C)c1Nc1c(-c2ccc(N(C)C)cc2)nc2cnccn12 nan
16299684 21484 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NC(=O)c2nn(C)c(=O)c3ccccc23)c1 nan
CHEMBL1315774 21484 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(NC(=O)c2nn(C)c(=O)c3ccccc23)c1 nan
16010795 21494 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 1 8 2.8 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
CHEMBL1315899 21494 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 1 8 2.8 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
16018148 21574 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 4 4.4 CCn1cc2c(n1)-c1c(oc(C(=O)Nc3cccc(C)c3C)c1C)CC2 nan
CHEMBL1316992 21574 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 4 4.4 CCn1cc2c(n1)-c1c(oc(C(=O)Nc3cccc(C)c3C)c1C)CC2 nan
5921518 21632 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 8 2.1 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(c3ccccc3)CC2)nc2ccccn2c1=O nan
CHEMBL1317700 21632 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 8 2.1 COCCCNC(=O)/C(C#N)=C/c1c(N2CCN(c3ccccc3)CC2)nc2ccccn2c1=O nan
4062026 21679 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 6 4.5 Cc1ccc(Cl)cc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCC4(CC3)OCCO4)cc2c1C nan
CHEMBL1318364 21679 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 6 4.5 Cc1ccc(Cl)cc1NC(=O)c1oc2ccc(S(=O)(=O)N3CCC4(CC3)OCCO4)cc2c1C nan
16027568 21680 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
CHEMBL1318374 21680 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
16028281 21694 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 7 3.4 CCc1cccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)c1 nan
CHEMBL1318465 21694 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 7 3.4 CCc1cccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)c1 nan
16017220 21715 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 8 1 6 4.8 Cc1nn(CCCC(=O)NCc2ccc(OC(C)C)cc2)c(=O)c2c1sc1ccccc12 nan
CHEMBL1318645 21715 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 8 1 6 4.8 Cc1nn(CCCC(=O)NCc2ccc(OC(C)C)cc2)c(=O)c2c1sc1ccccc12 nan
16027652 21766 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 8 4.3 CC(C)Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1319006 21766 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 8 4.3 CC(C)Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
2998240 21873 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 5 4.2 O=C(NCc1ccc(Cl)cc1)c1cc2c(nc3sccn32)s1 nan
CHEMBL1319990 21873 5 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 5 4.2 O=C(NCc1ccc(Cl)cc1)c1cc2c(nc3sccn32)s1 nan
16007411 21891 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 2 3 4.4 CC(C)c1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 nan
CHEMBL1320105 21891 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 2 3 4.4 CC(C)c1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1 nan
7692481 21929 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 3 3.4 COc1cc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2cc1OC nan
CHEMBL1320436 21929 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 3 3.4 COc1cc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2cc1OC nan
16019337 21999 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)cc1C nan
CHEMBL1321011 21999 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 3 0 9 2.6 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N2CCOCC2)c2sccc23)cc1C nan
16017632 22042 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 3 2 6 5.0 Cc1c(C(=O)Nc2ccccc2)sc2nc(-c3cc4cc(Cl)ccc4oc3=O)[nH]c(=O)c12 nan
CHEMBL1321440 22042 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 3 2 6 5.0 Cc1c(C(=O)Nc2ccccc2)sc2nc(-c3cc4cc(Cl)ccc4oc3=O)[nH]c(=O)c12 nan
15988428 22044 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 5 3.6 Cn1c(=O)n(-c2cccc(Cl)c2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1321495 22044 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 1 0 5 3.6 Cn1c(=O)n(-c2cccc(Cl)c2)c(=O)c2sc3ccccc3c21 nan
2988303 22046 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 6 3.2 Cn1c2ccc(F)cc2c2nnc(SCCN3CCCCC3)nc21 nan
CHEMBL1321509 22046 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 0 6 3.2 Cn1c2ccc(F)cc2c2nnc(SCCN3CCCCC3)nc21 nan
16017566 22077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1321733 22077 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
2158383 22230 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1323129 22230 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 6 1 6 2.1 CCOCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
6076700 22362 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 10 2 7 2.1 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2cccnc2)cc1 nan
CHEMBL1324242 22362 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 10 2 7 2.1 CCOc1ccc(C(=O)C2=C(O)C(=O)N(CCOCCO)C2c2cccnc2)cc1 nan
16805712 22406 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 2 9 1.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nnc12 nan
CHEMBL1324587 22406 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 8 2 9 1.0 Cn1c(=O)c2sccc2n2c(CCCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nnc12 nan
3152453 22645 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 8 1.1 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CCCO)c3nc12 nan
CHEMBL1326883 22645 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 8 1.1 Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)c(=N)n(CCCO)c3nc12 nan
5048043 22868 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1328648 22868 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 4 5.0 Cc1nn(C)cc1CN(C)C(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
135706200 22891 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 3.2 CN(Cc1nc(O)c2ccccc2n1)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 nan
CHEMBL1328897 22891 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 3.2 CN(Cc1nc(O)c2ccccc2n1)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 nan
5730619 22916 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C\C(=O)c3ccncc3)cc2)c1C nan
CHEMBL1329130 22916 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 7 3.3 Cc1noc(NS(=O)(=O)c2ccc(N/C=C\C(=O)c3ccncc3)cc2)c1C nan
2937900 22951 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 4.3 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1ccccc1F)c1cccs1 nan
CHEMBL1329400 22951 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 4.3 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1ccccc1F)c1cccs1 nan
2765497 22965 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 2.4 Cc1ccc(S(=O)(=O)C(C)C(=O)NCCS(=O)(=O)c2ccc(Cl)cc2)cc1 nan
CHEMBL1329544 22965 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 2.4 Cc1ccc(S(=O)(=O)C(C)C(=O)NCCS(=O)(=O)c2ccc(Cl)cc2)cc1 nan
44142302 22968 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 2.8 CN(C)c1ccc(C#Cc2ccc3cc(CCO)oc(=O)c3c2)cc1 nan
CHEMBL1329575 22968 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 2.8 CN(C)c1ccc(C#Cc2ccc3cc(CCO)oc(=O)c3c2)cc1 nan
16011595 23021 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 7 4.7 CCCCOc1ccc(CNC(=O)C2CCCN(c3nnc(-n4c(C)ccc4C)s3)C2)cc1 nan
CHEMBL1330008 23021 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 7 4.7 CCCCOc1ccc(CNC(=O)C2CCCN(c3nnc(-n4c(C)ccc4C)s3)C2)cc1 nan
4181210 23045 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 3.9 Cc1ccc(NC(=O)CSc2nnc3ccc4ccccc4n23)cc1 nan
CHEMBL1330254 23045 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 3.9 Cc1ccc(NC(=O)CSc2nnc3ccc4ccccc4n23)cc1 nan
1548033 23047 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 3 3 7 -0.6 CN(C)C(=O)CNc1nnc(S)nc1O nan
CHEMBL1330266 23047 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 229 3 3 7 -0.6 CN(C)C(=O)CNc1nnc(S)nc1O nan
1960924 23139 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 4 6 2.4 COc1ccc(C(=O)NC(=S)Nc2ccc3[nH]c(O)nc3c2)c(OC)c1 nan
CHEMBL1330933 23139 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 4 6 2.4 COc1ccc(C(=O)NC(=S)Nc2ccc3[nH]c(O)nc3c2)c(OC)c1 nan
16022880 23209 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 2 7 4.3 COc1ccccc1NC(=O)Cn1c(=O)c(CNc2ccccc2)cc2cc(OC)c(OC)cc21 nan
CHEMBL1331405 23209 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 9 2 7 4.3 COc1ccccc1NC(=O)Cn1c(=O)c(CNc2ccccc2)cc2cc(OC)c(OC)cc21 nan
995088 23248 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 4 4.9 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3C)c3cc(Br)ccc3n2)cc1 nan
CHEMBL1331738 23248 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 1 4 4.9 Cc1ccc(-c2cc(C(=O)NCc3cnn(C)c3C)c3cc(Br)ccc3n2)cc1 nan
4975488 23431 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 0 8 1.8 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(C)CC4)o3)nnc2c2ccccc12 nan
CHEMBL1333127 23431 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 0 8 1.8 Cc1nn2c(-c3ccc(S(=O)(=O)N4CCN(C)CC4)o3)nnc2c2ccccc12 nan
5219389 23490 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 2.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc3ccccc3oc2=O)c1 nan
CHEMBL1333624 23490 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 2.9 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc3ccccc3oc2=O)c1 nan
1298840 23500 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.1 CCn1c(SCC(=O)Nc2nc3ccccc3s2)nnc1-c1ccc(Br)cc1 nan
CHEMBL1333690 23500 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 7 5.1 CCn1c(SCC(=O)Nc2nc3ccccc3s2)nnc1-c1ccc(Br)cc1 nan
3586634 23521 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 5.2 CCCCn1c(SCC(=O)Nc2cccc(OC)c2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1333854 23521 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 5.2 CCCCn1c(SCC(=O)Nc2cccc(OC)c2)nc2c(sc3ccccc32)c1=O nan
1088584 23526 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 3 3.8 CC(=O)c1cn(CC(=O)Nc2ccc(C)cc2)c2ccccc12 nan
CHEMBL1333897 23526 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 3 3.8 CC(=O)c1cn(CC(=O)Nc2ccc(C)cc2)c2ccccc12 nan
1912959 23636 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5728937 23636 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5925428 23636 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
CHEMBL1334749 23636 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 4 7 2.5 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nccc(C)n3)cc2)n1 nan
5302178 23653 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
CHEMBL1334923 23653 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 0 5 2.3 CC1CCCN(S(=O)(=O)c2ccc3c(c2)c(=O)nc2ccccn23)C1 nan
15988344 23743 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 7 4.6 COc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2Cl)cc1 nan
CHEMBL1335550 23743 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 7 4.6 COc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2Cl)cc1 nan
3236871 23783 7 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 0 2 3.7 CCn1c(C)cc(=S)c2ccccc21 nan
CHEMBL1335833 23783 7 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 0 2 3.7 CCn1c(C)cc(=S)c2ccccc21 nan
3323389 23802 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 2 7 4.0 CC(=O)c1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
CHEMBL1336041 23802 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 2 7 4.0 CC(=O)c1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
135413771 23893 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 4.9 COc1cc(C2CC(c3c(C)cc(C)nc3O)=NN2c2ccccc2F)cc(OC)c1OC nan
CHEMBL1336821 23893 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 4.9 COc1cc(C2CC(c3c(C)cc(C)nc3O)=NN2c2ccccc2F)cc(OC)c1OC nan
2140203 23898 1 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 3 0 7 2.9 COc1ccc(-n2nnnc2-c2nc3ccccc3s2)cc1 nan
CHEMBL1336848 23898 1 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 3 0 7 2.9 COc1ccc(-n2nnnc2-c2nc3ccccc3s2)cc1 nan
2088251 23944 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 6 3.1 CCOc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1 nan
CHEMBL1337298 23944 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 0 6 3.1 CCOc1ccc(CC(=O)OCc2cc(=O)n3cc(Br)ccc3n2)cc1 nan
1301366 23959 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 5 4.1 O=C(CCSc1nnc2ccc3ccccc3n12)Nc1ccc(F)cc1 nan
CHEMBL1337428 23959 14 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 5 4.1 O=C(CCSc1nnc2ccc3ccccc3n12)Nc1ccc(F)cc1 nan
16015123 24001 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1cccc(C)c1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
CHEMBL1337810 24001 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1cccc(C)c1OCC(=O)Nc1nc(-c2ccc(Br)cc2)ns1 nan
16034823 24026 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 1 4 4.9 Cc1oc(-c2cccc(Br)c2)nc1CN1CCC(C(=O)NCc2ccccc2)CC1 nan
CHEMBL1338052 24026 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 1 4 4.9 Cc1oc(-c2cccc(Br)c2)nc1CN1CCC(C(=O)NCc2ccccc2)CC1 nan
2137854 24130 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1338842 24130 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
16023227 24144 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 2 6 4.7 O=C(Cn1c(=O)c(CNc2ccccc2)cc2cc3c(cc21)OCCO3)Nc1ccccc1Cl nan
CHEMBL1339042 24144 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 2 6 4.7 O=C(Cn1c(=O)c(CNc2ccccc2)cc2cc3c(cc21)OCCO3)Nc1ccccc1Cl nan
4012037 24214 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 5 4.3 c1coc(CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1339672 24214 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 5 4.3 c1coc(CSc2ncnc3c2oc2ccccc23)c1 nan
16406923 24353 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 3 6 2.3 Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NCC(=O)N[C@H](C(=O)O)C(C)C)c(C)c12 nan
CHEMBL1340985 24353 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 7 3 6 2.3 Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NCC(=O)N[C@H](C(=O)O)C(C)C)c(C)c12 nan
1859832 24400 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 0 7 4.3 COc1ccc(CCn2c(-c3ccc(F)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1OC nan
CHEMBL1341311 24400 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 0 7 4.3 COc1ccc(CCn2c(-c3ccc(F)cc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1OC nan
6402475 24635 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 4 4.2 Nc1nc(-c2ccc(Cl)cc2)nnc1-c1ccc(Br)cc1 nan
CHEMBL1343242 24635 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 4 4.2 Nc1nc(-c2ccc(Cl)cc2)nnc1-c1ccc(Br)cc1 nan
1831284 24665 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
4401304 24665 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
CHEMBL1343474 24665 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 Cc1cc(C)n(-c2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)n1 nan
3238813 24678 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 5 3.8 COc1ccc(-c2cc(C(=O)Nc3cccc(C(C)=O)c3)no2)cc1 nan
CHEMBL1343596 24678 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 1 5 3.8 COc1ccc(-c2cc(C(=O)Nc3cccc(C(C)=O)c3)no2)cc1 nan
2821813 24747 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 3 4.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc2ncsc2c1 nan
CHEMBL1344238 24747 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 2 1 3 4.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc2ncsc2c1 nan
3158796 24823 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 2 2 5 2.9 Cc1cccc(N2C(S)=C(C#N)C(=O)NC2c2ccco2)c1 nan
CHEMBL1344888 24823 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 2 2 5 2.9 Cc1cccc(N2C(S)=C(C#N)C(=O)NC2c2ccco2)c1 nan
2558333 24891 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 9 4.8 CCc1cc2c(SCc3nc(O)c4c(C)c(C(C)=O)sc4n3)ncnc2s1 nan
CHEMBL1345471 24891 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 9 4.8 CCc1cc2c(SCc3nc(O)c4c(C)c(C(C)=O)sc4n3)ncnc2s1 nan
7708092 24948 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 7 2.8 COc1ccc(C(=O)Nc2nnc(S(=O)(=O)Cc3ccccc3)s2)cc1 nan
CHEMBL1346001 24948 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 6 1 7 2.8 COc1ccc(C(=O)Nc2nnc(S(=O)(=O)Cc3ccccc3)s2)cc1 nan
4519571 25099 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 6 2.9 O=c1c2cc(Cl)ccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
CHEMBL1347185 25099 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 6 2.9 O=c1c2cc(Cl)ccc2nc(-c2ccc([N+](=O)[O-])cc2)n1O nan
24790251 25263 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 4 4.2 O=C(NCC1CCOCC1)c1ccc2nc(Cc3cccc(Cl)c3)oc2c1 nan
CHEMBL1348671 25263 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 4 4.2 O=C(NCC1CCOCC1)c1ccc2nc(Cc3cccc(Cl)c3)oc2c1 nan
16194270 25369 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.6 COc1cccc(CNC(=O)CSc2ccc(-c3cccs3)nn2)c1 nan
CHEMBL1349515 25369 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.6 COc1cccc(CNC(=O)CSc2ccc(-c3cccs3)nn2)c1 nan
2308471 25444 6 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 0 5 5.7 N#Cc1c(-c2ccc(F)cc2)cc(C2CC2)nc1SCC(=O)c1cccs1 nan
CHEMBL1350179 25444 6 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 0 5 5.7 N#Cc1c(-c2ccc(F)cc2)cc(C2CC2)nc1SCC(=O)c1cccs1 nan
1246228 25518 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 4.5 Cc1sc(NC(=O)c2oc3ccccc3c2C)c(C#N)c1C nan
CHEMBL1350806 25518 12 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 4 4.5 Cc1sc(NC(=O)c2oc3ccccc3c2C)c(C#N)c1C nan
3810755 25696 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
5224304 25696 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
CHEMBL1352306 25696 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 3.5 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(F)cc1)c1cc2ccccc2o1 nan
3710699 25808 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 0 5 3.2 CSc1nnc(-c2ccccc2SC)o1 nan
CHEMBL1353167 25808 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 3 0 5 3.2 CSc1nnc(-c2ccccc2SC)o1 nan
2408978 25903 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 4 3.8 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(Br)cc1 nan
CHEMBL1353794 25903 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 4 3.8 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(Br)cc1 nan
2137114 25993 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 5 4.4 Cc1ccc(C)c(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)c1 nan
CHEMBL1354500 25993 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 5 4.4 Cc1ccc(C)c(NC(=O)Cn2cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c3cc(F)ccc32)c1 nan
7177775 26022 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 4 0 7 1.8 Cc1ccc2nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc(=O)n2c1 nan
CHEMBL1354880 26022 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 4 0 7 1.8 Cc1ccc2nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc(=O)n2c1 nan
16015313 26026 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 5.8 COc1cccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4Cl)c3C)nc2C)c1 nan
CHEMBL1354922 26026 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 5.8 COc1cccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccccc4Cl)c3C)nc2C)c1 nan
16019333 26027 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.8 CCc1ccc(Nc2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)cc1 nan
CHEMBL1354928 26027 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.8 CCc1ccc(Nc2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)cc1 nan
15988332 26057 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 0 9 2.1 CC(=O)c1ccc(N2CCN(C(=O)CCc3nnc4n(C)c(=O)c5sccc5n34)CC2)cc1 nan
CHEMBL1355272 26057 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 0 9 2.1 CC(=O)c1ccc(N2CCN(C(=O)CCc3nnc4n(C)c(=O)c5sccc5n34)CC2)cc1 nan
15988502 26090 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 4 4.5 O=C(Cn1c(=O)nc(-c2ccccc2)c2ccccc21)Nc1ccc(Cl)cc1F nan
CHEMBL1355773 26090 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 4 4.5 O=C(Cn1c(=O)nc(-c2ccccc2)c2ccccc21)Nc1ccc(Cl)cc1F nan
2893260 26195 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 9 4.0 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc1nnc(C(C)C)s1 nan
CHEMBL1357131 26195 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 9 4.0 CCC(Sc1nnc2c3ccccc3n(C)c2n1)C(=O)Nc1nnc(C(C)C)s1 nan
16018894 26203 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 0 7 5.8 CCc1nnc(SCc2nc(-c3ccccc3)oc2C)c2cc3sccc3n12 nan
CHEMBL1357169 26203 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 0 7 5.8 CCc1nnc(SCc2nc(-c3ccccc3)oc2C)c2cc3sccc3n12 nan
16012142 26239 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 5.0 CC(CNC(=O)Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)c1ccccc1 nan
CHEMBL1357797 26239 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 5.0 CC(CNC(=O)Cn1ncc2c3ccccc3n(Cc3cccc(Cl)c3)c2c1=O)c1ccccc1 nan
16018042 26257 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 5 3.2 CN(C)c1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
CHEMBL1358052 26257 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 5 3.2 CN(C)c1ccc(CNC(=O)CCn2c(=O)c3cccn3c3ccc(F)cc32)cc1 nan
7711889 26317 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 0.2 Cn1c(CNS(=O)(=O)c2ccc(Cl)cc2)cc(=O)n(C)c1=O nan
CHEMBL1358800 26317 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 0.2 Cn1c(CNS(=O)(=O)c2ccc(Cl)cc2)cc(=O)n(C)c1=O nan
16018591 26380 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.7 COc1cc(NS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc(OC)c1OC nan
CHEMBL1359260 26380 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 7 2.7 COc1cc(NS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc(OC)c1OC nan
4302860 26391 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
4302861 26391 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1359331 26391 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.2 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
1270409 26401 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 11 -0.4 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC(C)(C)C)n2C)n(C)c1=O nan
CHEMBL1359403 26401 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 11 -0.4 Cn1c(=O)c2c(nc(Sc3ncnn3CC(=O)NC(C)(C)C)n2C)n(C)c1=O nan
1472977 26468 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 3 5.3 Brc1cc(Br)c2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 nan
CHEMBL1360031 26468 16 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 3 5.3 Brc1cc(Br)c2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 nan
5910118 26503 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1360299 26503 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 7 3.3 O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1cccc(O)c1)c1ccc2c(c1)OCCO2 nan
2519123 26562 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 1 5 2.2 Cc1cccc(-c2nnc(SCC(=O)NC3CC3)n2C)c1 nan
CHEMBL1360828 26562 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 1 5 2.2 Cc1cccc(-c2nnc(SCC(=O)NC3CC3)n2C)c1 nan
1637639 26620 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 7 1 5 3.8 CC(=O)c1sc(NC(=O)CCCOc2ccccc2C)nc1C nan
CHEMBL1361423 26620 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 7 1 5 3.8 CC(=O)c1sc(NC(=O)CCCOc2ccccc2C)nc1C nan
16029936 26632 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.5 Cc1cc(C(=O)Nc2c(C)nc3ccccn3c2=O)ccc1[N+](=O)[O-] nan
CHEMBL1361527 26632 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 2.5 Cc1cc(C(=O)Nc2c(C)nc3ccccn3c2=O)ccc1[N+](=O)[O-] nan
16021826 26648 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cc(Cl)ccc2C)c(-c2ccccc2)n1 nan
CHEMBL1361623 26648 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 4 5.1 CSc1ncc(C(=O)Nc2cc(Cl)ccc2C)c(-c2ccccc2)n1 nan
135399263 26771 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 3.7 Cc1cccc(C)c1NC(=O)CSc1nc(O)c2ccccc2n1 nan
CHEMBL1362620 26771 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 3.7 Cc1cccc(C)c1NC(=O)CSc1nc(O)c2ccccc2n1 nan
5225696 26885 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 2 3 2.3 CC1=C(C#N)C(NC(=O)c2ccccc2Cl)(C(F)(F)F)C(=O)N1 nan
CHEMBL1363628 26885 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 2 3 2.3 CC1=C(C#N)C(NC(=O)c2ccccc2Cl)(C(F)(F)F)C(=O)N1 nan
1300378 26937 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 5 3.9 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc2ccc(C)cn2)cc1 nan
CHEMBL1364136 26937 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 7 2 5 3.9 CC(=O)c1ccc(NC(=O)COc2ccccc2C(=O)Nc2ccc(C)cn2)cc1 nan
1207158 26961 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 2 5 4.7 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1cccc(C(=O)O)c1 nan
CHEMBL1364382 26961 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 2 5 4.7 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1cccc(C(=O)O)c1 nan
658008 26963 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.7 CCN(CC)C(=O)CSC1=C(C#N)C(c2cccs2)C=C(C)N1 nan
CHEMBL1364397 26963 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.7 CCN(CC)C(=O)CSC1=C(C#N)C(c2cccs2)C=C(C)N1 nan
1071060 27183 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 2 6 3.1 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2OC)c1C nan
CHEMBL1366254 27183 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 2 6 3.1 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2OC)c1C nan
711643 27232 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.7 Cc1ccc(C(=O)Nc2nnc(COc3ccccc3)s2)cc1 nan
CHEMBL1366637 27232 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 5 1 5 3.7 Cc1ccc(C(=O)Nc2nnc(COc3ccccc3)s2)cc1 nan
16030455 27233 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 4 6.0 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)Nc1ccccc1C(F)(F)F nan
CHEMBL1366645 27233 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 4 6.0 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)Nc1ccccc1C(F)(F)F nan
16010113 27241 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 3.3 CC(C)Oc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
CHEMBL1366755 27241 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 3.3 CC(C)Oc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
2115552 27266 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 3.2 Cc1[nH]c2ccccc2c1C(=O)COC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
CHEMBL1366975 27266 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 3.2 Cc1[nH]c2ccccc2c1C(=O)COC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
868037 27367 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 4 3.4 COc1cccc2c(S)c(CCC(C)=O)c(C)nc12 nan
CHEMBL1367790 27367 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 4 1 4 3.4 COc1cccc2c(S)c(CCC(C)=O)c(C)nc12 nan
1086871 27504 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 1 8 3.4 COc1ccc(Cc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2)cc1OC nan
CHEMBL1368875 27504 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 1 8 3.4 COc1ccc(Cc2nnc(NC(=O)c3ccc(OC)c(OC)c3)s2)cc1OC nan
2054025 27791 10 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 7 4.0 COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1 nan
CHEMBL1370794 27791 10 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 0 7 4.0 COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1 nan
2951249 27853 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
4590179 27853 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
CHEMBL1371319 27853 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(OC)c(C2C(C(=O)c3ccco3)=C(O)C(=O)N2Cc2cccnc2)c1 nan
1520515 27943 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 3 0 7 4.4 COc1ccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)cc1 nan
CHEMBL1372041 27943 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 3 0 7 4.4 COc1ccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)cc1 nan
15988500 28005 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 584 13 2 9 3.7 CCCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
CHEMBL1372455 28005 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 584 13 2 9 3.7 CCCCCNC(=O)C1CCC(Cn2c(=O)c3sccc3n(CC(=O)NCc3cccc(OC)c3OC)c2=O)CC1 nan
16030415 28088 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.0 Cc1ccc2nc(COc3ccccc3NC(=O)c3ccccc3F)cc(=O)n2c1 nan
CHEMBL1372965 28088 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 4.0 Cc1ccc2nc(COc3ccccc3NC(=O)c3ccccc3F)cc(=O)n2c1 nan
3141921 28114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 4 4.1 N#CCSc1nc(-c2ccccc2)nc2ccc(F)cc12 nan
CHEMBL1373143 28114 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 4 4.1 N#CCSc1nc(-c2ccccc2)nc2ccc(F)cc12 nan
5740603 28226 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 3.3 COc1ccc2[nH]c(/C(C#N)=C\c3ccc(C(=O)O)cc3)nc2c1 nan
CHEMBL1373830 28226 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 2 4 3.3 COc1ccc2[nH]c(/C(C#N)=C\c3ccc(C(=O)O)cc3)nc2c1 nan
4965542 28255 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 11 0.2 C=CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
CHEMBL1374122 28255 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 11 0.2 C=CCSc1nnc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)s1 nan
3496625 28256 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 7 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OCc3ccccc3)cc2)no1 nan
CHEMBL1374123 28256 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 7 5.2 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OCc3ccccc3)cc2)no1 nan
2945949 28352 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 5 2.5 O=C(CCN1C(=O)c2cccc3cccc(c23)C1=O)Nc1ccon1 nan
CHEMBL1374764 28352 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 1 5 2.5 O=C(CCN1C(=O)c2cccc3cccc(c23)C1=O)Nc1ccon1 nan
15989514 28392 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 535 8 1 7 3.7 O=C(Cn1c(=O)n(CCCS(=O)(=O)C2CCCCC2)c(=O)c2ccccc21)Nc1ccc(F)c(Cl)c1 nan
CHEMBL1375013 28392 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 535 8 1 7 3.7 O=C(Cn1c(=O)n(CCCS(=O)(=O)C2CCCCC2)c(=O)c2ccccc21)Nc1ccc(F)c(Cl)c1 nan
2212703 28458 10 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 4 3.0 O=C(O)Cn1cc(C(=O)c2cccs2)c2ccccc21 nan
CHEMBL1375453 28458 10 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 4 1 4 3.0 O=C(O)Cn1cc(C(=O)c2cccs2)c2ccccc21 nan
2471579 28482 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 9 2 7 5.5 COc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
CHEMBL1375669 28482 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 9 2 7 5.5 COc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
3167528 28498 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 7 2.9 Cc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
CHEMBL1375776 28498 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 7 2.9 Cc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
2397772 28530 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 10 1.1 COc1cc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)ccc1OCCC(C)C nan
CHEMBL1376204 28530 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 10 1.1 COc1cc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)ccc1OCCC(C)C nan
1767629 28594 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1ccccc1Cl)C3 nan
CHEMBL1376703 28594 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1ccccc1Cl)C3 nan
16024679 28680 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 3.3 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)c1 nan
CHEMBL1377672 28680 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 3.3 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)c1 nan
135520779 28696 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 6 3.3 CCCc1nc2oc3c(O)ncnc3c2c2c1COC(C)(C)C2 nan
CHEMBL1377764 28696 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 6 3.3 CCCc1nc2oc3c(O)ncnc3c2c2c1COC(C)(C)C2 nan
16194561 28704 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)s1 nan
CHEMBL1377828 28704 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 10 2.1 Cc1nnc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)s1 nan
16025409 28710 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 2.6 NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
CHEMBL1377886 28710 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 2.6 NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1cccc(F)c1)S2(=O)=O nan
2816168 28744 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 8 1.2 CCOC(=O)c1nnn2c1nc(N1CCN(C)CC1)c1ccccc12 nan
CHEMBL1378192 28744 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 8 1.2 CCOC(=O)c1nnn2c1nc(N1CCN(C)CC1)c1ccccc12 nan
16021577 28771 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 2.3 CCCNC(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
CHEMBL1378416 28771 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 2.3 CCCNC(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
20886481 28912 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 4 3.9 CC(C)Oc1ccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)cc1 nan
CHEMBL1379683 28912 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 5 1 4 3.9 CC(C)Oc1ccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)cc1 nan
2731492 28913 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 3 2 3 3.7 COc1cccc(NC(S)=Nc2cc(C)cc(C)n2)c1 nan
CHEMBL1379684 28913 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 3 2 3 3.7 COc1cccc(NC(S)=Nc2cc(C)cc(C)n2)c1 nan
614385 28959 83 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 2 4 2.7 Nc1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
CHEMBL1380161 28959 83 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 2 4 2.7 Nc1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
16187343 28998 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 0 7 4.1 CC(=O)c1ccc(-c2nnc(CCC(=O)N(C)Cc3cccc4cnccc34)o2)s1 nan
CHEMBL1380413 28998 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 0 7 4.1 CC(=O)c1ccc(-c2nnc(CCC(=O)N(C)Cc3cccc4cnccc34)o2)s1 nan
705209 29000 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 2 6 2.7 N#Cc1c(N)n(-c2ccc(C(=O)O)cc2)c2nc3ccccc3nc12 nan
CHEMBL1380440 29000 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 2 6 2.7 N#Cc1c(N)n(-c2ccc(C(=O)O)cc2)c2nc3ccccc3nc12 nan
3724835 29026 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
5033543 29026 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1380602 29026 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 3.3 CCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
1445317 29030 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 1 2 3.4 CCc1cc2ccc(C)cc2nc1S nan
CHEMBL1380640 29030 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 203 1 1 2 3.4 CCc1cc2ccc(C)cc2nc1S nan
4430260 29221 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 4 0 6 2.2 O=[N+]([O-])c1cccc(OCc2cn3cccnc3n2)c1 nan
CHEMBL1382302 29221 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 4 0 6 2.2 O=[N+]([O-])c1cccc(OCc2cn3cccnc3n2)c1 nan
3785801 29317 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 1 6 4.6 CCCCN(CCCC)C(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
CHEMBL1383130 29317 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 8 1 6 4.6 CCCCN(CCCC)C(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
3151314 29324 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 2 8 1.6 N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
CHEMBL1383245 29324 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 2 8 1.6 N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1 nan
16241852 29382 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.6 CCc1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1.CN(C)C=O nan
CHEMBL1383752 29382 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 7 2.6 CCc1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1.CN(C)C=O nan
9550688 29416 2 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 0 6 3.2 O=c1sc(N2CCN(c3ccc(F)cc3)CC2)nc2ccsc12 nan
CHEMBL1384034 29416 2 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 2 0 6 3.2 O=c1sc(N2CCN(c3ccc(F)cc3)CC2)nc2ccsc12 nan
23004552 29440 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 0 8 0.5 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3sccn3c2=O)CC1 nan
CHEMBL1384314 29440 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 0 8 0.5 CCOC(=O)N1CCN(S(=O)(=O)c2c(C)nc3sccn3c2=O)CC1 nan
1830897 29513 12 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 5 2.7 O=c1c(Cl)c(NS(=O)(=O)c2ccccc2)cnn1-c1ccccc1 nan
CHEMBL1384824 29513 12 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 5 2.7 O=c1c(Cl)c(NS(=O)(=O)c2ccccc2)cnn1-c1ccccc1 nan
2488909 29638 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 7 1.6 COC(=O)CNC(=O)CSc1nnc2cc(C)c3ccccc3n12 nan
CHEMBL1386026 29638 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 7 1.6 COC(=O)CNC(=O)CSc1nnc2cc(C)c3ccccc3n12 nan
1301168 29801 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.6 Cc1ccc(S(=O)(=O)c2nc(Nc3ccccc3C#N)sc2Cl)cc1 nan
CHEMBL1387246 29801 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 6 4.6 Cc1ccc(S(=O)(=O)c2nc(Nc3ccccc3C#N)sc2Cl)cc1 nan
6264256 29814 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 1 8 4.1 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)cc1OC nan
CHEMBL1387384 29814 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 1 8 4.1 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)cc1OC nan
20904611 29899 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 10 1 9 1.8 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
CHEMBL1388050 29899 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 10 1 9 1.8 COCCCn1c(=O)c2sccc2n2c(CCCC(=O)NCC3CCCO3)nnc12 nan
2819135 29977 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 3.3 COc1cccc(-c2c(C#N)c(SC)nc3cc(C)nn23)c1 nan
CHEMBL1388609 29977 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 3.3 COc1cccc(-c2c(C#N)c(SC)nc3cc(C)nn23)c1 nan
900107 30060 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 6 -1.0 NC(=O)Cn1cnc2nc3n(c2c1=O)CCC3 nan
CHEMBL1389257 30060 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 6 -1.0 NC(=O)Cn1cnc2nc3n(c2c1=O)CCC3 nan
1934247 30087 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 9 2 6 5.3 COCCCNC(=O)c1c(NC(=O)c2ccccc2Cl)n(Cc2ccccc2)c2nc3ccccc3nc12 nan
CHEMBL1389486 30087 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 9 2 6 5.3 COCCCNC(=O)c1c(NC(=O)c2ccccc2Cl)n(Cc2ccccc2)c2nc3ccccc3nc12 nan
2012798 30177 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 4.4 Cc1ccc(Cn2c(N)c(S(=O)(=O)c3cccs3)c3nc4ccccc4nc32)cc1 nan
CHEMBL1390254 30177 9 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 4.4 Cc1ccc(Cn2c(N)c(S(=O)(=O)c3cccs3)c3nc4ccccc4nc32)cc1 nan
6290194 30287 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 1 7 3.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
CHEMBL1391210 30287 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 1 7 3.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCN2CCOCC2)c1 nan
16193052 30347 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(Br)cc1 nan
CHEMBL1391769 30347 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 1 4 2.9 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccc(Br)cc1 nan
886207 30503 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.3 CCNc1nc(C)c2cc(Br)c(=O)n(CC)c2n1 nan
CHEMBL1393118 30503 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.3 CCNc1nc(C)c2cc(Br)c(=O)n(CC)c2n1 nan
2889346 30518 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 1 4 3.5 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cn2)C1c1ccc(F)cc1 nan
CHEMBL1393200 30518 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 1 4 3.5 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cn2)C1c1ccc(F)cc1 nan
6622405 30522 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 2.9 CCn1c(=O)c2cc(C(=O)N(C)CC(OC)OC)sc2c2ccccc21 nan
CHEMBL1393223 30522 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 2.9 CCn1c(=O)c2cc(C(=O)N(C)CC(OC)OC)sc2c2ccccc21 nan
5181542 30550 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(Cl)cc2)no1 nan
CHEMBL1393467 30550 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 6 4.0 Cc1cc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2ccc(Cl)cc2)no1 nan
20917879 30557 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 6 2.4 CN(Cc1ccco1)S(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
CHEMBL1393505 30557 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 0 6 2.4 CN(Cc1ccco1)S(=O)(=O)c1cc(F)ccc1CN1C(=O)c2cccnc2C1=O nan
20888749 30590 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CC(C)OC(C)C2)s1 nan
CHEMBL1393784 30590 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 2.7 CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CC(C)OC(C)C2)s1 nan
2135574 30660 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 9 1 8 4.4 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OCC)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1394559 30660 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 9 1 8 4.4 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OCC)cc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
16033270 30661 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 5.3 Cc1ccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
CHEMBL1394566 30661 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 5 5.3 Cc1ccc(NC(=O)c2sc3ncnc(N(C)C4CCCCC4)c3c2C)cc1 nan
16025819 30666 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 4 5.4 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1394644 30666 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 1 4 5.4 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
16018820 30674 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 8 4.7 CCc1nnc(SCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2cc3oc(C)cc3n12 nan
CHEMBL1394778 30674 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 8 4.7 CCc1nnc(SCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2cc3oc(C)cc3n12 nan
5144289 30697 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 4 3.4 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1394997 30697 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 4 3.4 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 nan
16031990 30711 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.7 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Br)cc3)nn2)s1 nan
CHEMBL1395113 30711 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 1 6 4.7 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(Br)cc3)nn2)s1 nan
6200398 30730 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 7 2.8 CNc1oc(/C=C/c2cc(OC)c(OC)c(OC)c2)nc1C#N nan
CHEMBL1395288 30730 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 6 1 7 2.8 CNc1oc(/C=C/c2cc(OC)c(OC)c(OC)c2)nc1C#N nan
16033416 30739 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 5 5.8 CCOc1ccc(-c2cc(C(=O)NCc3ccc(OC)cc3)c3c(-c4ccc(F)cc4)[nH]nc3n2)cc1 nan
CHEMBL1395414 30739 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 5 5.8 CCOc1ccc(-c2cc(C(=O)NCc3ccc(OC)cc3)c3c(-c4ccc(F)cc4)[nH]nc3n2)cc1 nan
5323079 30765 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 4 5.2 CCOc1ccc(NC(=O)CSc2c3c(nc4ccccc24)CCCC3)cc1 nan
CHEMBL1395837 30765 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 6 1 4 5.2 CCOc1ccc(NC(=O)CSc2c3c(nc4ccccc24)CCCC3)cc1 nan
16024553 30768 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1395881 30768 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
5296856 30790 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 4 2.6 Cc1cccn2c3c(c(=O)nc12)C(c1cccc(F)c1)CC(=O)N3 nan
CHEMBL1396255 30790 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 4 2.6 Cc1cccn2c3c(c(=O)nc12)C(c1cccc(F)c1)CC(=O)N3 nan
1730979 30793 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 3 6.9 O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc(-c2cccs2)nc2ccccc12 nan
CHEMBL1396294 30793 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 3 6.9 O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc(-c2cccs2)nc2ccccc12 nan
16019329 30797 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 0 9 2.6 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1396323 30797 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 0 9 2.6 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(C)cc4)nnn3c3ccsc23)CC1 nan
16018658 30808 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.9 CCc1cccc(C)c1NC(=O)C(CC)Sc1nncn2c1cc1occc12 nan
CHEMBL1396473 30808 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.9 CCc1cccc(C)c1NC(=O)C(CC)Sc1nncn2c1cc1occc12 nan
20885686 30874 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 6 1.4 Cc1nn(CCCC(=O)NCc2ccc(F)cc2)c(=O)c2nccn12 nan
CHEMBL1397376 30874 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 6 1.4 Cc1nn(CCCC(=O)NCc2ccc(F)cc2)c(=O)c2nccn12 nan
4904384 30892 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 1 3 3.5 COc1cc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2cc1OC nan
CHEMBL1397630 30892 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 1 3 3.5 COc1cc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2cc1OC nan
22517504 30943 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 2.3 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
CHEMBL1398370 30943 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 6 2.3 Cc1ccccc1C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
15989335 30958 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 13 2 7 4.4 CCOc1ccc(NC(=O)Cn2c(=O)n(CCCCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3ccccc32)cc1 nan
CHEMBL1398481 30958 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 13 2 7 4.4 CCOc1ccc(NC(=O)Cn2c(=O)n(CCCCC(=O)NCCc3ccc(Cl)cc3)c(=O)c3ccccc32)cc1 nan
16022088 30967 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 0 6 4.8 COc1ccc2c(c1)c1c(c(=O)n(-c3cc(Cl)ccc3C)c(=O)n1Cc1ccc(F)cc1)n2C nan
CHEMBL1398563 30967 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 0 6 4.8 COc1ccc2c(c1)c1c(c(=O)n(-c3cc(Cl)ccc3C)c(=O)n1Cc1ccc(F)cc1)n2C nan
3594054 31062 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 5 6.2 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Br)c1 nan
CHEMBL1399458 31062 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 5 6.2 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1cccc(Br)c1 nan
16017733 31075 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 5 2.8 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccccc1C(F)(F)F nan
CHEMBL1399598 31075 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 5 2.8 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccccc1C(F)(F)F nan
16023027 31184 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
CHEMBL1400601 31184 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 6 2.8 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2)s1 nan
2992172 31325 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 5 1 7 2.8 CCOC(=O)c1sc(NC(=O)c2ccc(OC(C)=O)cc2)nc1C nan
CHEMBL1401867 31325 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 5 1 7 2.8 CCOC(=O)c1sc(NC(=O)c2ccc(OC(C)=O)cc2)nc1C nan
3124205 31379 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 4 3.3 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(F)cc2)cc1 nan
CHEMBL1402337 31379 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 4 3.3 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(F)cc2)cc1 nan
3833466 31420 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 8 4.3 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
CHEMBL1402650 31420 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 8 4.3 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2c2cc(C)on2)cc1 nan
1451311 31433 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 0 5 3.4 CCOC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
CHEMBL1402735 31433 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 5 0 5 3.4 CCOC(=O)CSc1nc(C(C)C)nc2ccccc12 nan
698553 31459 35 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1 nan
CHEMBL1403001 31459 35 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.1 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccccc1 nan
2679217 31509 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 5 3.5 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 nan
CHEMBL1403552 31509 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 5 3.5 COc1ccc2oc(C(=O)Nc3nccs3)c(C)c2c1 nan
3705005 31597 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 0 0 1 4.2 Brc1cc(Br)c2nc3c(cc2c1)CCC3 nan
CHEMBL1404252 31597 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 0 0 1 4.2 Brc1cc(Br)c2nc3c(cc2c1)CCC3 nan
738260 31658 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.1 COc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cn1 nan
CHEMBL1404986 31658 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.1 COc1cc2ccccc2cc1C(=O)Nc1ccc(Cl)cn1 nan
16406961 31669 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 2 1 6 2.8 Cc1c(CC(=O)N2C[C@@H]3C[C@H](C2)Cn2c3cccc2=O)c(=O)oc2cc(O)c(Cl)cc12 nan
CHEMBL1405140 31669 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 2 1 6 2.8 Cc1c(CC(=O)N2C[C@@H]3C[C@H](C2)Cn2c3cccc2=O)c(=O)oc2cc(O)c(Cl)cc12 nan
1277429 31730 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 0 7 3.5 c1ccc(-c2cc3c(N4CCN(c5ncccn5)CC4)ncnc3s2)cc1 nan
CHEMBL1405710 31730 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 0 7 3.5 c1ccc(-c2cc3c(N4CCN(c5ncccn5)CC4)ncnc3s2)cc1 nan
135681062 31745 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 2 6 0.1 O=C(NCCCN1CCCC1=O)c1c(O)nc2ccccn2c1=O nan
CHEMBL1405883 31745 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 2 6 0.1 O=C(NCCCN1CCCC1=O)c1c(O)nc2ccccn2c1=O nan
2479912 31756 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 7 1.2 Cn1c(N)c(C(=O)COc2ccc(Cl)cc2Cl)c(=O)n(C)c1=O nan
CHEMBL1405949 31756 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 7 1.2 Cn1c(N)c(C(=O)COc2ccc(Cl)cc2Cl)c(=O)n(C)c1=O nan
665818 31919 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.2 CNc1ncnc2c3cc(OC)ccc3n(C)c12 nan
CHEMBL1407387 31919 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.2 CNc1ncnc2c3cc(OC)ccc3n(C)c12 nan
2956880 31924 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 4 2.7 O=C(Nc1ccc(N2CCOCC2)cc1)C1CC(=O)N(c2ccc(F)cc2)C1 nan
CHEMBL1407427 31924 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 4 2.7 O=C(Nc1ccc(N2CCOCC2)cc1)C1CC(=O)N(c2ccc(F)cc2)C1 nan
7080333 31971 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 3.9 Cc1c(-c2cccc(NC(=O)Cc3ccccc3)c2)nc2ncccn12 nan
CHEMBL1407681 31971 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 3.9 Cc1c(-c2cccc(NC(=O)Cc3ccccc3)c2)nc2ncccn12 nan
16016996 32076 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 6 2.4 Cc1ccc(Cl)cc1N1CCN(C(=O)C(C)n2ncn3cccc3c2=O)CC1 nan
CHEMBL1408470 32076 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 3 0 6 2.4 Cc1ccc(Cl)cc1N1CCN(C(=O)C(C)n2ncn3cccc3c2=O)CC1 nan
236431 32105 68 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 1 1 3.6 CC(=O)Nc1ccc(Br)c2ccccc12 nan
CHEMBL1408731 32105 68 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 1 1 3.6 CC(=O)Nc1ccc(Br)c2ccccc12 nan
16019396 32205 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 10 4.2 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1ccc3c(c1)OCO3)c1sccc12 nan
CHEMBL1409519 32205 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 10 4.2 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1ccc3c(c1)OCO3)c1sccc12 nan
6625357 32220 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 6 1.3 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c2nccn12 nan
CHEMBL1409636 32220 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 6 1.3 Cc1nn(CCCC(=O)NCCc2ccccc2)c(=O)c2nccn12 nan
302041 32573 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 7 1.9 Cn1c2ccccc2c2nnc(SCCN3CCOCC3)nc21 nan
CHEMBL1412491 32573 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 0 7 1.9 Cn1c2ccccc2c2nnc(SCCN3CCOCC3)nc21 nan
2100500 32585 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1c(Cl)cccc1NC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O nan
CHEMBL1412600 32585 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1c(Cl)cccc1NC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O nan
2059848 32710 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 8 3.2 Cc1cc(C)nc(SCC(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)n1 nan
CHEMBL1413582 32710 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 8 3.2 Cc1cc(C)nc(SCC(=O)Nc2ccc(S(=O)(=O)Nc3onc(C)c3C)cc2)n1 nan
16017166 32769 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 4.0 COc1cccc(CNC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
CHEMBL1414014 32769 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 6 4.0 COc1cccc(CNC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
2919306 32799 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(C)o2)C1c1cccc(Br)c1 nan
CHEMBL1414306 32799 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 4.0 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(C)o2)C1c1cccc(Br)c1 nan
16015068 32806 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1c(Cl)cccc1NC(=O)CSc1cc(-c2ccccc2)ncn1 nan
CHEMBL1414379 32806 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1c(Cl)cccc1NC(=O)CSc1cc(-c2ccccc2)ncn1 nan
16010393 32817 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 2 0 3 5.9 Cc1cccc2c1-c1sc(C(=O)N(C)c3cccc(C(F)(F)F)c3)cc1CO2 nan
CHEMBL1414451 32817 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 2 0 3 5.9 Cc1cccc2c1-c1sc(C(=O)N(C)c3cccc(C(F)(F)F)c3)cc1CO2 nan
3245690 33137 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 7 4.2 Cc1nc2ccc3nc(NC(=O)c4ccc5c(c4)OCCO5)sc3c2s1 nan
CHEMBL1417231 33137 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 7 4.2 Cc1nc2ccc3nc(NC(=O)c4ccc5c(c4)OCCO5)sc3c2s1 nan
24792497 33222 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 8 2.5 COc1ccc2cc(C#N)c(SCC(=O)Nc3nonc3C)nc2c1 nan
CHEMBL1417975 33222 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 8 2.5 COc1ccc2cc(C#N)c(SCC(=O)Nc3nonc3C)nc2c1 nan
2473907 33381 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.1 CCOC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
CHEMBL1419339 33381 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.1 CCOC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
2980984 33473 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 1 6 4.3 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccccc2)CO1 nan
CHEMBL1420144 33473 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 2 1 6 4.3 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccccc2)CO1 nan
16745931 33620 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 3 2 6 3.9 Cc1ccc(-c2csc3nc4cc(C(=O)NC5CCC(O)CC5)ccc4c(=O)n23)cc1 nan
CHEMBL1421354 33620 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 3 2 6 3.9 Cc1ccc(-c2csc3nc4cc(C(=O)NC5CCC(O)CC5)ccc4c(=O)n23)cc1 nan
2138543 33698 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
CHEMBL1422079 33698 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 2 7 3.6 Cc1cccc(-c2nnn3c2nc(NCCc2ccc(S(N)(=O)=O)cc2)c2ccccc23)c1 nan
6045016 33859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 9 1 7 4.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1423355 33859 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 9 1 7 4.3 CCOc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
3725185 33896 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 4 5.2 CN(C)c1ccc(P(=O)(OCc2ccccc2)C(O)c2ccc(Cl)cc2)cc1 nan
CHEMBL1423606 33896 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 4 5.2 CN(C)c1ccc(P(=O)(OCc2ccccc2)C(O)c2ccc(Cl)cc2)cc1 nan
135420429 33900 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 9 3.4 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1nnc(C)s1 nan
CHEMBL1423657 33900 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 9 3.4 CCC(Sc1nc(O)c(C#N)c(-c2ccccc2)n1)C(=O)Nc1nnc(C)s1 nan
950417 34046 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 0 7 1.2 Cc1cccn2c(=O)c(C=C(C#N)C#N)c(N3CCN(C)CC3)nc12 nan
CHEMBL1424893 34046 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 0 7 1.2 Cc1cccn2c(=O)c(C=C(C#N)C#N)c(N3CCN(C)CC3)nc12 nan
4008202 34367 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 9 1.9 CCOC(=O)c1sc2nc(C)nc(SCC(=O)NC3CCS(=O)(=O)C3)c2c1C nan
CHEMBL1427679 34367 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 9 1.9 CCOC(=O)c1sc2nc(C)nc(SCC(=O)NC3CCS(=O)(=O)C3)c2c1C nan
2810151 34395 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 1 4 3.7 O=C(Nc1nc2ccccc2c(=O)s1)c1ccc(F)cc1Cl nan
CHEMBL1427961 34395 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 1 4 3.7 O=C(Nc1nc2ccccc2c(=O)s1)c1ccc(F)cc1Cl nan
4603734 34590 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 2.3 O=C(COc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl nan
CHEMBL1429555 34590 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 2.3 O=C(COc1ncnc2ccccc12)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl nan
2369101 34597 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 5 3.2 CCN1C(=O)C(=C2C=C(C)N(Cc3ccco3)C(C)=C2)C(=O)N(CC)C1=S nan
CHEMBL1429586 34597 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 0 5 3.2 CCN1C(=O)C(=C2C=C(C)N(Cc3ccco3)C(C)=C2)C(=O)N(CC)C1=S nan
6110891 34607 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.4 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1429670 34607 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.4 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 nan
3186593 34830 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.3 CC1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
CHEMBL1431426 34830 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.3 CC1CCN(C(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)CC1 nan
4836291 34930 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 3 4.9 CCC1CCCCN1C(=O)COc1c(Br)cc(Br)c2cccnc12 nan
CHEMBL1432322 34930 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 3 4.9 CCC1CCCCN1C(=O)COc1c(Br)cc(Br)c2cccnc12 nan
3236746 34947 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 7 2 4 3.9 CCOc1ccc(OCC)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
CHEMBL1432463 34947 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 7 2 4 3.9 CCOc1ccc(OCC)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
5186080 35032 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 0 5 3.1 CC1(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)CC1(Cl)Cl nan
CHEMBL1433143 35032 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 3 0 5 3.1 CC1(C(=O)OCc2cc(=O)n3cc(Br)ccc3n2)CC1(Cl)Cl nan
16025762 35071 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)C1 nan
CHEMBL1433427 35071 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 5 4.1 CCOC(=O)C1CCCN(C(=O)c2ccc(-n3ccc4ccccc43)s2)C1 nan
16031695 35141 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 2.7 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 nan
CHEMBL1434575 35141 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 4 1 5 2.7 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 nan
1003863 35158 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 2 5 5.6 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(Cl)cc4F)sc3n2)c1 nan
CHEMBL1434727 35158 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 2 5 5.6 COc1cccc(-c2ccc3c(N)c(C(=O)Nc4ccc(Cl)cc4F)sc3n2)c1 nan
16404473 35189 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 545 8 1 8 3.7 COc1cc(OC)c(OC)cc1/C=C1\Oc2cc(OCC(=O)N3Cc4ccccc4C[C@H]3C(=O)O)ccc2C1=O nan
CHEMBL1435093 35189 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 545 8 1 8 3.7 COc1cc(OC)c(OC)cc1/C=C1\Oc2cc(OCC(=O)N3Cc4ccccc4C[C@H]3C(=O)O)ccc2C1=O nan
24891925 35208 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 7 2.3 O=C(CSc1nnc2ccc(-c3ccc(F)cc3)nn12)NCC1CCCO1 nan
CHEMBL1435281 35208 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 7 2.3 O=C(CSc1nnc2ccc(-c3ccc(F)cc3)nn12)NCC1CCCO1 nan
16416480 35212 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
5457481 35212 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
CHEMBL1435346 35212 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 6 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1 nan
16034509 35216 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.6 CN(C)c1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1435377 35216 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.6 CN(C)c1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
15989215 35229 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 8 2.8 COc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc32)cc1 nan
CHEMBL1435575 35229 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 1 8 2.8 COc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc32)cc1 nan
4281326 35287 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 4 5.3 Cc1cccc(C)c1OCC(=O)Nc1c(C(=O)c2ccccc2)oc2ccccc12 nan
CHEMBL1436278 35287 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 4 5.3 Cc1cccc(C)c1OCC(=O)Nc1c(C(=O)c2ccccc2)oc2ccccc12 nan
16009492 35379 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3cccc(NC(=O)c4ccccc4F)c3)cc(=O)n12 nan
CHEMBL1437588 35379 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.0 Cc1csc2nc(COc3cccc(NC(=O)c4ccccc4F)c3)cc(=O)n12 nan
16015683 35381 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 1 5 5.9 O=C(Nc1ccc2nc(SCC(=O)N3CCc4ccccc43)sc2c1)c1ccc(Cl)cc1 nan
CHEMBL1437631 35381 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 5 1 5 5.9 O=C(Nc1ccc2nc(SCC(=O)N3CCc4ccccc43)sc2c1)c1ccc(Cl)cc1 nan
16025792 35393 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 5 4.9 COc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
CHEMBL1437725 35393 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 1 5 4.9 COc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4ccc5ccccc54)s3)CC2)cc1 nan
4523316 35498 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 0 5 2.6 CN(C(=O)c1cc2c(=O)n3ccccc3nc2n1C)C1CCCCC1 nan
CHEMBL1438580 35498 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 0 5 2.6 CN(C(=O)c1cc2c(=O)n3ccccc3nc2n1C)C1CCCCC1 nan
16012068 35557 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 2.6 Cc1cc(=O)n2nc(N3CCC(C(=O)NCc4ccc(Cl)cc4)CC3)sc2n1 nan
CHEMBL1439177 35557 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 1 7 2.6 Cc1cc(=O)n2nc(N3CCC(C(=O)NCc4ccc(Cl)cc4)CC3)sc2n1 nan
3846910 35578 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 2 6 4.2 Cc1ccccc1NC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
CHEMBL1439341 35578 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 2 6 4.2 Cc1ccccc1NC(=O)c1sc2nc(N3CCOCC3)c3c(c2c1N)CCCC3 nan
4246549 35741 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 4 5.2 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCCCCC4)cc3c2C)c(C)c1 nan
CHEMBL1440777 35741 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 4 5.2 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCCCCC4)cc3c2C)c(C)c1 nan
4230097 35760 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 9 4.1 O=C(O)CCCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
CHEMBL1440951 35760 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 9 1 9 4.1 O=C(O)CCCCCn1c(SCc2cc(=O)n3cc(Cl)ccc3n2)nc2ccsc2c1=O nan
3272255 35894 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 2 7 0.7 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCC(C(N)=O)CC3)c(=O)c2c1C nan
CHEMBL1442168 35894 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 2 7 0.7 Cc1sc2ncn(CC(=O)NCCCC(=O)N3CCC(C(N)=O)CC3)c(=O)c2c1C nan
1077468 35923 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
CHEMBL1442429 35923 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CCCN4CCOCC4)c3nc12 nan
20876076 35937 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 0.8 COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1442544 35937 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 0.8 COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
7217841 35982 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 6 2.9 Cc1nnc2ccc(-c3ccc(NC(=O)c4ccco4)cc3)nn12 nan
CHEMBL1442956 35982 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 6 2.9 Cc1nnc2ccc(-c3ccc(NC(=O)c4ccco4)cc3)nn12 nan
2975734 35991 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
CHEMBL1443010 35991 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 0 7 2.3 CCOC(=O)C1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
4611621 36147 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 4.8 COc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(c3ccc(OC)c(OC)c3)C2)cc1 nan
CHEMBL1444507 36147 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 4.8 COc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(c3ccc(OC)c(OC)c3)C2)cc1 nan
817359 36164 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 3 3.6 CC(=O)c1ccc(NC(=S)NC(=O)Cc2ccc(Cl)cc2)cc1 nan
CHEMBL1444699 36164 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 3 3.6 CC(=O)c1ccc(NC(=S)NC(=O)Cc2ccc(Cl)cc2)cc1 nan
4051948 36167 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 4.6 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccc(Cl)c2)o1 nan
CHEMBL1444743 36167 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 4.6 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccc(Cl)c2)o1 nan
3186591 36204 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.5 CC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1445043 36204 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 8 0.5 CC1CCCCN1C(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
16187836 36298 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 10 1.1 COc1ccccc1-c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1445914 36298 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 10 1.1 COc1ccccc1-c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16017757 36414 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 2.9 CCc1ccc(NC(=O)Cn2ccn(-c3cccc(Cl)c3)c(=O)c2=O)cc1 nan
CHEMBL1446963 36414 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 1 5 2.9 CCc1ccc(NC(=O)Cn2ccn(-c3cccc(Cl)c3)c(=O)c2=O)cc1 nan
2769301 36571 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 4 3.7 COc1ccc(-c2cc(C(=O)Nc3ccccc3F)on2)cc1 nan
CHEMBL1448341 36571 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 4 3.7 COc1ccc(-c2cc(C(=O)Nc3ccccc3F)on2)cc1 nan
3658309 36725 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 11 1 8 4.8 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
CHEMBL1449439 36725 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 11 1 8 4.8 COc1cc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCN2CCOCC2)ccc1OCCC(C)C nan
3652194 36790 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 1 0 2 5.5 Brc1cc(Br)c2nc(-c3cccs3)ccc2c1 nan
CHEMBL1449966 36790 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 1 0 2 5.5 Brc1cc(Br)c2nc(-c3cccs3)ccc2c1 nan
3244704 36898 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 7 3.3 COc1ccc(C2C=C(c3cccs3)Nc3nc(CCCO)nn32)cc1 nan
CHEMBL1450888 36898 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 7 3.3 COc1ccc(C2C=C(c3cccs3)Nc3nc(CCCO)nn32)cc1 nan
1774540 37075 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1cccc(Cl)c1)C3 nan
CHEMBL1452222 37075 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 0 4 5.0 O=c1oc2c3c(ccc2c2ccccc12)OCN(Cc1cccc(Cl)c1)C3 nan
649434 37163 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 4.2 CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
CHEMBL1452945 37163 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 4.2 CCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nccs2)c1 nan
16187616 37313 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 10 2.8 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4cc(C)on4)nn23)cc1OC nan
CHEMBL1454124 37313 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 10 2.8 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4cc(C)on4)nn23)cc1OC nan
17580690 37350 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 1 1 2 3.5 Cc1c(C(=O)N2CC(C)OC(C)C2)[nH]c2ccc(Br)cc12 nan
CHEMBL1454451 37350 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 1 1 2 3.5 Cc1c(C(=O)N2CC(C)OC(C)C2)[nH]c2ccc(Br)cc12 nan
18204435 37445 5 None -48 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 2 6 3.5 CNC(=O)c1ccc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)cc1 nan
CHEMBL1455259 37445 5 None -48 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 4 2 6 3.5 CNC(=O)c1ccc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)cc1 nan
1265180 37552 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 8 1.0 CCCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1456231 37552 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 8 1.0 CCCn1c(SCC(=O)NC2CCCC2)nc2c1c(=O)n(C)c(=O)n2C nan
24793479 37670 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 6 3.3 COc1ccc(C(=O)NNC(=O)CSc2nc(C(C)C)nc3ccccc23)cc1 nan
CHEMBL1457367 37670 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 2 6 3.3 COc1ccc(C(=O)NNC(=O)CSc2nc(C(C)C)nc3ccccc23)cc1 nan
24819691 37762 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 3 4 3.2 COc1ccc2cc(OCC(=O)NNC(=O)Nc3ccc(F)cc3)ccc2c1 nan
CHEMBL1458070 37762 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 3 4 3.2 COc1ccc2cc(OCC(=O)NNC(=O)Nc3ccc(F)cc3)ccc2c1 nan
675984 37867 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 0 2 4.0 O=C(COc1ccc2ccccc2c1Br)N1CCCCC1 nan
CHEMBL1458979 37867 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 0 2 4.0 O=C(COc1ccc2ccccc2c1Br)N1CCCCC1 nan
866601 37999 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 5 3.4 O=C(NC1CCCCCC1)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1460115 37999 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 1 5 3.4 O=C(NC1CCCCCC1)c1cc2c(=O)n3ccccc3nc2s1 nan
20912606 38188 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 0 7 3.4 CN(C)CCN(Cc1ccccc1)C(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
CHEMBL1461808 38188 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 0 7 3.4 CN(C)CCN(Cc1ccccc1)C(=O)C1CCN(c2ncnc3c2nc2n3CCCCC2)CC1 nan
2745719 38413 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 2.8 CC(=O)Nc1nccc(-c2cc(-c3ccccc3)no2)n1 nan
CHEMBL1463690 38413 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 1 5 2.8 CC(=O)Nc1nccc(-c2cc(-c3ccccc3)no2)n1 nan
741378 38569 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 3.4 COC(=O)Sc1nnc(-c2ccc(Br)cc2)o1 nan
CHEMBL1464821 38569 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 0 6 3.4 COC(=O)Sc1nnc(-c2ccc(Br)cc2)o1 nan
203396 38600 88 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 3 2.8 O=c1c(Br)c(Br)cnn1-c1ccccc1 nan
CHEMBL1465040 38600 88 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 1 0 3 2.8 O=c1c(Br)c(Br)cnn1-c1ccccc1 nan
3518230 38620 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
4024784 38620 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
CHEMBL1465171 38620 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 6 4.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccc(Cl)cc1)c1cc2ccccc2o1 nan
24791767 38672 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 0 6 3.5 CCN(Cc1cnn(C)c1)C(=O)c1cc(COc2ccc3c(c2)CCCC3)on1 nan
CHEMBL1465549 38672 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 0 6 3.5 CCN(Cc1cnn(C)c1)C(=O)c1cc(COc2ccc3c(c2)CCCC3)on1 nan
16241464 38885 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 8 2.7 CN(C)C=O.O=[N+]([O-])c1cccc(COc2ncnc3cc([N+](=O)[O-])ccc23)c1 nan
CHEMBL1467247 38885 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 8 2.7 CN(C)C=O.O=[N+]([O-])c1cccc(COc2ncnc3cc([N+](=O)[O-])ccc23)c1 nan
1244301 38984 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 2 3.8 Cc1c(C(=O)NCc2ccccc2F)oc2ccccc12 nan
CHEMBL1468217 38984 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 2 3.8 Cc1c(C(=O)NCc2ccccc2F)oc2ccccc12 nan
18561646 39032 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 9 0.6 CC(C)Cc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1468525 39032 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 9 0.6 CC(C)Cc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
4257704 39090 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 1 7 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)c1 nan
CHEMBL1468952 39090 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 1 7 3.4 CCN(CC)S(=O)(=O)c1ccc(N2CCOCC2)c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)c1 nan
20957237 39226 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 9 1.7 COc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
CHEMBL1470126 39226 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 9 1.7 COc1ccc(CNC(=O)CCc2nnc3ccc(N4CCC5(CC4)OCCO5)nn23)cc1 nan
1261892 39229 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 2 5 3.7 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3ccc(Br)cc23)cc1 nan
CHEMBL1470208 39229 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 6 2 5 3.7 NS(=O)(=O)c1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3ccc(Br)cc23)cc1 nan
2725142 39341 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 7 2.4 COc1nc(N)c(C#N)c(-c2ccc(N(C)CCC#N)cc2)c1C#N nan
CHEMBL1471123 39341 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 7 2.4 COc1nc(N)c(C#N)c(-c2ccc(N(C)CCC#N)cc2)c1C#N nan
15988569 39526 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 6 5.5 Cc1ccc(-c2nc(-c3cc4cccc(OCc5ccc(F)cc5)c4oc3=O)no2)cc1 nan
CHEMBL1472849 39526 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 6 5.5 Cc1ccc(-c2nc(-c3cc4cccc(OCc5ccc(F)cc5)c4oc3=O)no2)cc1 nan
1166244 39537 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1cccc(C)c1NC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
CHEMBL1472996 39537 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1cccc(C)c1NC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
16025417 39555 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 8 1 7 5.3 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)cc1 nan
CHEMBL1473284 39555 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 8 1 7 5.3 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)cc1 nan
16009695 39621 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 4 1 6 4.5 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCCC1 nan
CHEMBL1474245 39621 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 4 1 6 4.5 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCCC1 nan
2158398 39627 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 6 3.8 COc1ccc(Cl)cc1NC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1474329 39627 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 6 3.8 COc1ccc(Cl)cc1NC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
16009720 39632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(CNc2nc3c(-c4ccc(C)cc4)nnn3c3ccccc23)cc1 nan
CHEMBL1474419 39632 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(CNc2nc3c(-c4ccc(C)cc4)nnn3c3ccccc23)cc1 nan
16016110 39670 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 1 7 4.8 Cc1ccc(CNc2ccc(-c3nc(-c4ccco4)no3)cc2[N+](=O)[O-])cc1 nan
CHEMBL1474896 39670 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 1 7 4.8 Cc1ccc(CNc2ccc(-c3nc(-c4ccco4)no3)cc2[N+](=O)[O-])cc1 nan
16033296 39672 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccccc1CNC(=O)c1sc2ncnc(N(C)C3CCCCC3)c2c1C nan
CHEMBL1474937 39672 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 5.0 Cc1ccccc1CNC(=O)c1sc2ncnc(N(C)C3CCCCC3)c2c1C nan
3155029 39723 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 5 2.1 COc1ccc(CCNC(=O)CN2C(=O)COc3ccc(C)cc32)cc1OC nan
CHEMBL1475587 39723 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 7 1 5 2.1 COc1ccc(CCNC(=O)CN2C(=O)COc3ccc(C)cc32)cc1OC nan
16020275 39726 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 9 2 7 4.6 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)cc3)c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc32)cc1 nan
CHEMBL1475630 39726 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 9 2 7 4.6 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccc(OC)cc3)c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc32)cc1 nan
16415433 39728 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
5513689 39728 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
CHEMBL1475648 39728 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 7 3.0 COc1ccc(-c2cc3ccc(O)c(CN4CCOCC4)c3oc2=O)cc1OC nan
3646895 39746 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 7 4.9 CCOCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1475830 39746 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 7 4.9 CCOCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
16020214 39750 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 644 7 2 8 4.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc21)Nc1ccc(Br)cc1F nan
CHEMBL1475923 39750 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 644 7 2 8 4.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc21)Nc1ccc(Br)cc1F nan
15990518 39763 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.9 CCOC(=O)c1cccc(NC(=O)c2cc3cc4cc(OC)ccc4nc3s2)c1 nan
CHEMBL1476197 39763 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.9 CCOC(=O)c1cccc(NC(=O)c2cc3cc4cc(OC)ccc4nc3s2)c1 nan
16018050 39803 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC nan
CHEMBL1476725 39803 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)cc1OC nan
18572231 39827 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 8 2.6 CCOc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
CHEMBL1477019 39827 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 8 2.6 CCOc1ccc(-c2ccc3nnc(SCC(=O)NCC4CCCO4)n3n2)cc1 nan
5294687 39859 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 8 2 4 5.3 CCCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1477360 39859 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 8 2 4 5.3 CCCOc1ccc(C(CC(=O)O)NC(=O)c2sc3ccccc3c2Cl)cc1 nan
3096467 39931 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
5751261 39931 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
CHEMBL1477993 39931 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 8 0 5 4.2 CCn1c(/C=C/N(C(C)=O)c2ccccc2)[n+](CCCS(=O)(=O)[O-])c2cc(Cl)c(Cl)cc21 nan
2027019 39998 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 7 5.3 CSc1nc(SCC(=O)O)c2sc3nc(-c4ccccc4)c4c(c3c2n1)CCC4 nan
CHEMBL1478587 39998 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 7 5.3 CSc1nc(SCC(=O)O)c2sc3nc(-c4ccccc4)c4c(c3c2n1)CCC4 nan
2487220 40113 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 3.8 CCn1cc(C(=O)OCC(=O)Nc2cccc(Cl)c2Cl)c(=O)c2ccc(C)nc21 nan
CHEMBL1479594 40113 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 3.8 CCn1cc(C(=O)OCC(=O)Nc2cccc(Cl)c2Cl)c(=O)c2ccc(C)nc21 nan
16024523 40174 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 5 3.6 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1480079 40174 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 5 3.6 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
16019201 40188 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3cc(C)cc(C)c3)c2=O)cc1 nan
CHEMBL1480191 40188 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3cc(C)cc(C)c3)c2=O)cc1 nan
5925055 40383 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1481881 40383 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 7 3.0 O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1cccc(Cl)c1)c1ccc2c(c1)OCCO2 nan
7258994 40391 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 8 1.9 Cc1ccc2nc(SCC(=O)Nc3ccc4c(c3)OCCO4)nc(=O)n2c1 nan
CHEMBL1481935 40391 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 1 8 1.9 Cc1ccc2nc(SCC(=O)Nc3ccc4c(c3)OCCO4)nc(=O)n2c1 nan
1470918 40473 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 3.7 Cc1ccccc1C(=O)NN(C)c1nc2ccccc2nc1C(F)(F)F nan
CHEMBL1482653 40473 20 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 4 3.7 Cc1ccccc1C(=O)NN(C)c1nc2ccccc2nc1C(F)(F)F nan
3122172 40517 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccccc1Cl nan
CHEMBL1483069 40517 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 3 4.6 CC(=O)C1=C(O)C(=O)N(c2cccc(Br)c2)C1c1ccccc1Cl nan
1093408 40567 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 2 5 4.3 COCc1cc(C)nc2sc(C(=O)Nc3ccccc3Br)c(N)c12 nan
CHEMBL1483523 40567 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 2 5 4.3 COCc1cc(C)nc2sc(C(=O)Nc3ccccc3Br)c(N)c12 nan
1868051 40599 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 3.4 CSc1nc(SCC(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
CHEMBL1483727 40599 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 3.4 CSc1nc(SCC(=O)O)c2c3c(sc2n1)COC(C)(C)C3 nan
4968512 40698 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 209 1 2 5 2.1 Nc1ccccc1-c1nnc(S)s1 nan
CHEMBL1484500 40698 8 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 209 1 2 5 2.1 Nc1ccccc1-c1nnc(S)s1 nan
1130974 40733 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 6 3.5 CCOc1ccc(NC(=O)c2sc(NC(C)=O)c(C(=O)OC)c2C)cc1 nan
CHEMBL1484851 40733 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 6 3.5 CCOc1ccc(NC(=O)c2sc(NC(C)=O)c(C(=O)OC)c2C)cc1 nan
16023029 40865 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 6 2.9 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccc(F)cc2)s1 nan
CHEMBL1486082 40865 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 6 2.9 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccc(F)cc2)s1 nan
2122608 40889 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 6 1 5 4.1 CC(=O)c1sc(NC(=O)COc2ccc(C(C)C)c(C)c2)nc1C nan
CHEMBL1486351 40889 7 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 6 1 5 4.1 CC(=O)c1sc(NC(=O)COc2ccc(C(C)C)c(C)c2)nc1C nan
15988496 40931 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 0 6 5.2 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(-c2ccc(F)c(Cl)c2)c(=O)c2sc3ccccc3c21 nan
CHEMBL1486634 40931 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 0 6 5.2 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(-c2ccc(F)c(Cl)c2)c(=O)c2sc3ccccc3c21 nan
5058050 41037 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 0 5 4.0 CCCCN(CCCC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1487547 41037 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 0 5 4.0 CCCCN(CCCC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
1120443 41161 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 7 5.9 CCOc1cc(-c2nc3c(c(CC)nn3-c3ccccc3)c3cc(OC)c(OC)cc23)ccc1O nan
CHEMBL1488401 41161 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 7 5.9 CCOc1cc(-c2nc3c(c(CC)nn3-c3ccccc3)c3cc(OC)c(OC)cc23)ccc1O nan
1415522 41240 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 6.4 CCN(CC)C(=O)c1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
CHEMBL1488995 41240 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 6.4 CCN(CC)C(=O)c1sc2nc(-c3cccs3)cc(-c3ccc(Cl)cc3)c2c1N nan
2014552 41356 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 9 2.0 CCOc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)ccc1OCCN1CCOCC1 nan
CHEMBL1489906 41356 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 9 2.0 CCOc1cc(C2C(C#N)=C(N)SC(N)=C2C#N)ccc1OCCN1CCOCC1 nan
2873834 41431 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 7 4.3 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CCCC2=N1 nan
CHEMBL1490473 41431 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 7 4.3 CC1=C(C(=O)OCC2CCCO2)C(c2coc3ccccc3c2=O)C2=C(O)CCCC2=N1 nan
1536777 41675 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 4.4 Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C nan
CHEMBL1492096 41675 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 4.4 Cc1sc2ncnc(NC3CCN(Cc4ccccc4)CC3)c2c1C nan
2419865 41775 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 5 0 5 3.7 COc1ccc(C(C)=O)cc1COc1nc(C)nc2ccccc12 nan
CHEMBL1492888 41775 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 5 0 5 3.7 COc1ccc(C(C)=O)cc1COc1nc(C)nc2ccccc12 nan
1102906 41783 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 2 4 3.0 O=C(O)c1ccc(N2C(=O)c3cccc4c(C(=O)O)ccc(c34)C2=O)cc1 nan
CHEMBL1492995 41783 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 2 4 3.0 O=C(O)c1ccc(N2C(=O)c3cccc4c(C(=O)O)ccc(c34)C2=O)cc1 nan
3467703 41863 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 2 0 2 3.4 C=CCN1C(=O)c2cccc3c(Br)ccc(c23)C1=O nan
CHEMBL1493801 41863 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 2 0 2 3.4 C=CCN1C(=O)c2cccc3c(Br)ccc(c23)C1=O nan
7711621 41884 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 2 7 -0.5 CC(=O)Nc1ccc(S(=O)(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1 nan
CHEMBL1494013 41884 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 2 7 -0.5 CC(=O)Nc1ccc(S(=O)(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1 nan
681202 41953 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 3 3 3 3.6 Cc1sc(N=C(S)Nc2ccc(F)cc2)c(C(N)=O)c1C nan
CHEMBL1494694 41953 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 3 3 3 3.6 Cc1sc(N=C(S)Nc2ccc(F)cc2)c(C(N)=O)c1C nan
2451170 42033 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 6 2.8 CCOC(=O)c1sc2nc(C)nc(S)c2c1C nan
CHEMBL1495560 42033 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 6 2.8 CCOC(=O)c1sc2nc(C)nc(S)c2c1C nan
16017877 42075 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 4 2.6 Cc1ccccc1Cn1ccn(-c2ccc(F)c(F)c2)c(=O)c1=O nan
CHEMBL1495957 42075 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 3 0 4 2.6 Cc1ccccc1Cn1ccn(-c2ccc(F)c(F)c2)c(=O)c1=O nan
2917647 42198 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 6 3.5 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(Cl)cc1)c1ccco1 nan
CHEMBL1497016 42198 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 6 3.5 O=C(C1=C(O)C(=O)N(c2ncccn2)C1c1ccc(Cl)cc1)c1ccco1 nan
3493986 42219 8 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 8 1 6 5.3 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccccc3C)cc2)cc1 nan
CHEMBL1497174 42219 8 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 8 1 6 5.3 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccccc3C)cc2)cc1 nan
4260589 42256 5 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 9 2 6 4.8 CCCC1(c2ccccc2)NC(=O)N(CC(=O)Nc2sc(-c3ccccc3)cc2C(=O)OCC)C1=O nan
CHEMBL1497431 42256 5 None -5 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 9 2 6 4.8 CCCC1(c2ccccc2)NC(=O)N(CC(=O)Nc2sc(-c3ccccc3)cc2C(=O)OCC)C1=O nan
1234241 42317 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 1 1 5 2.9 Cc1nnc(S)c2nn(-c3ccccc3F)c(C)c12 nan
CHEMBL1498110 42317 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 1 1 5 2.9 Cc1nnc(S)c2nn(-c3ccccc3F)c(C)c12 nan
4056802 42520 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 2.8 Cc1cccn2c(=O)c3cc(C(=O)NCCCOC(C)C)sc3nc12 nan
CHEMBL1499876 42520 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 6 1 6 2.8 Cc1cccn2c(=O)c3cc(C(=O)NCCCOC(C)C)sc3nc12 nan
2908462 42525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 1 6 3.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1)c1ccco1 nan
CHEMBL1499902 42525 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 1 6 3.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccccc1)c1ccco1 nan
2551439 42657 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 0 8 1.7 COc1ccc(OCCOC(=O)c2nc3nccc(C)n3n2)cc1 nan
CHEMBL1501099 42657 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 0 8 1.7 COc1ccc(OCCOC(=O)c2nc3nccc(C)n3n2)cc1 nan
716763 42681 29 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 3.3 O=C(O)c1ccc(N2C(=O)c3cccc4cccc(c34)C2=O)cc1 nan
CHEMBL1501298 42681 29 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 3 3.3 O=C(O)c1ccc(N2C(=O)c3cccc4cccc(c34)C2=O)cc1 nan
5012247 42732 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 11 -2.0 CCN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1CCS(=O)(=O)C1 nan
CHEMBL1501780 42732 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 11 -2.0 CCN(C(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1CCS(=O)(=O)C1 nan
2816746 43071 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 2 6 4.1 CCOC(=O)c1c(N=C(S)NCc2ccccc2)sc2c1CCN(C(=O)OCC)C2 nan
CHEMBL1504775 43071 9 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 2 6 4.1 CCOC(=O)c1c(N=C(S)NCc2ccccc2)sc2c1CCN(C(=O)OCC)C2 nan
2363951 43085 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 9 0.2 Cn1c(N)c(C(=O)COC(=O)CCC(=O)c2ccc(F)cc2)c(=O)n(C)c1=O nan
CHEMBL1504909 43085 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 9 0.2 Cn1c(N)c(C(=O)COC(=O)CCC(=O)c2ccc(F)cc2)c(=O)n(C)c1=O nan
3238944 43132 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.4 Cc1cccc(Nc2nn3c(=O)c4ccccc4nc3s2)c1 nan
CHEMBL1505300 43132 13 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.4 Cc1cccc(Nc2nn3c(=O)c4ccccc4nc3s2)c1 nan
7190519 43178 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 9 2.4 O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1nccs1 nan
CHEMBL1505657 43178 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 9 2.4 O=C(CSc1ccc2nnc(-c3ccccn3)n2n1)Nc1nccs1 nan
3154081 43391 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 8 4.0 CCCOc1cccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1507529 43391 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 8 4.0 CCCOc1cccc(C2C(C(=O)c3ccco3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
1803037 43578 9 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 5 6.1 Cc1cccc(NC(=O)CSc2nc(C)c(CC(=O)c3ccc(Br)cc3)c(C)c2C#N)c1C nan
CHEMBL1509120 43578 9 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 7 1 5 6.1 Cc1cccc(NC(=O)CSc2nc(C)c(CC(=O)c3ccc(Br)cc3)c(C)c2C#N)c1C nan
3772923 43590 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 1 3 2.4 Cc1nc(S)c(C#N)c2c1CCCC2 nan
CHEMBL1509207 43590 23 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 0 1 3 2.4 Cc1nc(S)c(C#N)c2c1CCCC2 nan
3150659 43723 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.3 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1510456 43723 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 3.3 Cc1nc(SCC(=O)NCC2CCCO2)c2c3c(sc2n1)CCCC3 nan
2318166 43757 7 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 4.7 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCCC3)c2C#N)cc1 nan
CHEMBL1510689 43757 7 None -4 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 6 4.7 CC(C)c1ccc(-c2c(C#N)c(N)nc(SCC(=O)N3CCCCCC3)c2C#N)cc1 nan
4382156 43831 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 4 2.2 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccccc1F nan
CHEMBL1511309 43831 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 1 4 2.2 O=C(CCCN1C(=O)c2cccnc2C1=O)Nc1ccccc1F nan
5825936 43888 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 8 3.3 C=CCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
CHEMBL1511801 43888 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 520 10 1 8 3.3 C=CCOc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCN2CCOCC2)cc1 nan
1234706 43919 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 6 3.5 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nc(C)cc(C)n2)cc1 nan
CHEMBL1512389 43919 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 6 3.5 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2nc(C)cc(C)n2)cc1 nan
18572258 43930 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 7 2.9 O=C(CSc1nnc2ccc(-c3ccc(Br)cc3)nn12)NCC1CCCO1 nan
CHEMBL1512477 43930 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 7 2.9 O=C(CSc1nnc2ccc(-c3ccc(Br)cc3)nn12)NCC1CCCO1 nan
7205055 43959 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 6 3.3 CCN1CCN(Cc2c(O)ccc3cc(-c4ccc(OC)cc4)c(=O)oc23)CC1 nan
CHEMBL1512819 43959 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 6 3.3 CCN1CCN(Cc2c(O)ccc3cc(-c4ccc(OC)cc4)c(=O)oc23)CC1 nan
53229784 43961 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
5457315 43961 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
CHEMBL1512839 43961 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 5 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1 nan
16026424 43995 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 0 7 3.4 COC(=O)c1sc2ccccc2c1S(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1513424 43995 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 0 7 3.4 COC(=O)c1sc2ccccc2c1S(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
16019493 44010 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(S(=O)(=O)NCCc2nnc3ccc(SCc4ccccc4C)nn23)cc1 nan
CHEMBL1513611 44010 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(S(=O)(=O)NCCc2nnc3ccc(SCc4ccccc4C)nn23)cc1 nan
15989126 44014 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 11 2 7 4.7 Cc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1513634 44014 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 11 2 7 4.7 Cc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
1252356 44030 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 6 5.5 Cc1cc(C)cc(NC(=O)CSc2oc(-c3ccccc3)nc2S(=O)(=O)c2ccccc2)c1 nan
CHEMBL1513969 44030 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 6 5.5 Cc1cc(C)cc(NC(=O)CSc2oc(-c3ccccc3)nc2S(=O)(=O)c2ccccc2)c1 nan
16406807 44034 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 3 6 2.7 CC[C@@H](C)[C@H](NC(=O)CNC(=O)Cc1c(C)c2c(cc(C)c3c(C)coc32)oc1=O)C(=O)O nan
CHEMBL1514043 44034 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 8 3 6 2.7 CC[C@@H](C)[C@H](NC(=O)CNC(=O)Cc1c(C)c2c(cc(C)c3c(C)coc32)oc1=O)C(=O)O nan
2135573 44065 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 8 1 8 4.1 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1514550 44065 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 8 1 8 4.1 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
16018084 44107 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
CHEMBL1515147 44107 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 9 1 6 3.6 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1 nan
4302940 44108 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 5.4 CCn1cc(CNC(=O)c2cc(-c3ccc(C)cc3)nc3ccc(Br)cc23)c(C)n1 nan
CHEMBL1515178 44108 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 5.4 CCn1cc(CNC(=O)c2cc(-c3ccc(C)cc3)nc3ccc(Br)cc23)c(C)n1 nan
15989010 44123 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 1 8 3.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c1 nan
CHEMBL1515330 44123 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 1 8 3.0 Cc1cccc(Cn2c(=O)n(CCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c1 nan
20885696 44284 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 9 1 8 1.4 COc1ccc(CCNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1OC nan
CHEMBL1517314 44284 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 9 1 8 1.4 COc1ccc(CCNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1OC nan
1488779 44508 23 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 4 4.6 COc1ccc(Oc2nccc(-c3ccc(F)cc3)c2C#N)cc1 nan
CHEMBL1519391 44508 23 None -1 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 4 4.6 COc1ccc(Oc2nccc(-c3ccc(F)cc3)c2C#N)cc1 nan
3154197 44509 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 8 0.6 Cn1c(=O)c2c(ncn2CC(O)CNc2cccc(Cl)c2)n(C)c1=O nan
CHEMBL1519401 44509 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 8 0.6 Cn1c(=O)c2c(ncn2CC(O)CNc2cccc(Cl)c2)n(C)c1=O nan
5309980 44551 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 1 6 2.5 CC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
CHEMBL1519790 44551 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 1 6 2.5 CC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
20873023 44640 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccc(OC)cc2)c1=O nan
CHEMBL1520622 44640 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 7 1 10 -0.3 CCOC(=O)CNC(=O)Cn1cnc2c(nnn2-c2ccc(OC)cc2)c1=O nan
135407280 44668 35 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 2 1 5 2.4 CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1520797 44668 35 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 2 1 5 2.4 CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
2868262 44732 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Br)cc1 nan
CHEMBL1521342 44732 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 1 3 4.7 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1ccc(Br)cc1 nan
646901 44783 3 None -4 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 3.6 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cc(C)on1)OCO3 nan
CHEMBL1521729 44783 3 None -4 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 3.6 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cc(C)on1)OCO3 nan
16012248 44799 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.0 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)Nc3ccc(C)c(Cl)c3)c(C)nc21 nan
CHEMBL1521906 44799 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.0 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)Nc3ccc(C)c(Cl)c3)c(C)nc21 nan
5086217 44821 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.6 CCOC(=O)c1c(N=C(S)Nc2ccc(F)cc2)sc2c1CCC2 nan
CHEMBL1522109 44821 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 4 4.6 CCOC(=O)c1c(N=C(S)Nc2ccc(F)cc2)sc2c1CCC2 nan
2929681 44893 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 2 7 2.6 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CCc4ccccc4)c3nc12 nan
CHEMBL1522811 44893 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 2 7 2.6 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(CCc4ccccc4)c3nc12 nan
352022 44935 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 0 7 0.5 CCCSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
CHEMBL1523163 44935 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 3 0 7 0.5 CCCSc1nc2c(c(=O)n(C)c(=O)n2C)n1C nan
861889 44945 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.0 Cc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
CHEMBL1523239 44945 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 3 4.0 Cc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
4099138 44950 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 9 2 8 3.5 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1523295 44950 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 9 2 8 3.5 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1ccc2c(c1)OCO2 nan
5760985 45231 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 4 4.8 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(F)cc1)c1ccc(Br)cc1 nan
CHEMBL1525962 45231 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 4 4.8 O=C(C1=C(O)C(=O)N(c2ccccn2)C1c1ccc(F)cc1)c1ccc(Br)cc1 nan
3186625 45454 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 2 9 0.7 CC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
CHEMBL1527889 45454 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 2 9 0.7 CC(=O)Nc1cccc(NC(=O)CSc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 nan
1166606 45526 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 8 1 6 5.3 COc1ccc(NC(=O)CCSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)n2)cc1 nan
CHEMBL1528550 45526 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 8 1 6 5.3 COc1ccc(NC(=O)CCSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)n2)cc1 nan
1109837 45607 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 nan
CHEMBL1529226 45607 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 nan
4413149 45630 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1ccc(Cl)cc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1529453 45630 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 1 4 3.1 Cc1ccc(Cl)cc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
6086754 45693 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1529980 45693 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.9 COc1cccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
4881121 45733 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 0 7 2.0 CCc1cc2c(SCC(=O)N(C)C3CCS(=O)(=O)C3)ncnc2s1 nan
CHEMBL1530432 45733 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 5 0 7 2.0 CCc1cc2c(SCC(=O)N(C)C3CCS(=O)(=O)C3)ncnc2s1 nan
15988929 45786 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 12 2 8 3.7 COc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1530799 45786 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 12 2 8 3.7 COc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
2956077 45853 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 3 3.4 COc1ccc2cc(Br)ccc2c1CC(=O)NCC1CCCO1 nan
CHEMBL1531449 45853 21 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 3 3.4 COc1ccc2cc(Br)ccc2c1CC(=O)NCC1CCCO1 nan
646794 46273 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 6 2.4 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccnc1)c1ccco1 nan
CHEMBL1535358 46273 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 1 6 2.4 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1cccnc1)c1ccco1 nan
9551120 46409 0 None -14 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 3.0 CCOC(=O)Cn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
CHEMBL1536779 46409 0 None -14 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 3 1 6 3.0 CCOC(=O)Cn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
5297702 46510 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 1 3 4.2 Nc1c2c(nc3cccc(Cl)c13)N(c1ccccc1)CC2 nan
CHEMBL1537611 46510 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 1 3 4.2 Nc1c2c(nc3cccc(Cl)c13)N(c1ccccc1)CC2 nan
5069161 46704 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
CHEMBL1539200 46704 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 2 6 3.5 O=C(CCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
1373674 46774 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 8 0.1 Cn1c(=O)c2c(nc(SCC(=O)NC3CCCC3)n2C)n(C)c1=O nan
CHEMBL1539818 46774 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 1 8 0.1 Cn1c(=O)c2c(nc(SCC(=O)NC3CCCC3)n2C)n(C)c1=O nan
20888840 46815 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 0 8 2.2 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
CHEMBL1540109 46815 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 0 8 2.2 CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCN(C)CC2)s1 nan
2823604 46895 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 3 0 4 3.2 COC(=O)CSc1ccnc2cc(Cl)ccc12 nan
CHEMBL1540846 46895 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 3 0 4 3.2 COC(=O)CSc1ccnc2cc(Cl)ccc12 nan
2502748 46929 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 7 3.0 COc1cc(CN(C)Cc2cc(=O)n3ccsc3n2)ccc1OC(F)F nan
CHEMBL1541111 46929 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 7 3.0 COc1cc(CN(C)Cc2cc(=O)n3ccsc3n2)ccc1OC(F)F nan
3119316 46988 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 4 3.9 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(Br)cc2)cc1 nan
CHEMBL1541516 46988 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 4 3.9 COc1ccc(C2C(C(C)=O)=C(O)C(=O)N2c2ccc(Br)cc2)cc1 nan
4885704 47041 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccccc1F nan
CHEMBL1541978 47041 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 1 7 2.5 O=c1c2ccccc2cnn1Cc1nnc(S)n1-c1ccccc1F nan
20884256 47223 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 0.5 Cc1nn(CC(=O)NCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
CHEMBL1543621 47223 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 0.5 Cc1nn(CC(=O)NCCN2CCOCC2)c(=O)c2cc3sccc3n12 nan
1451421 47324 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 0 6 3.9 CCOC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
CHEMBL1544289 47324 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 7 0 6 3.9 CCOC(=O)CSc1nc(COc2ccccc2)nc2ccccc12 nan
7120054 47400 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
CHEMBL1544911 47400 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 2 1 5 3.8 COc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
3192298 47420 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 2 0 5 1.3 Cc1nc2ccccn2c1C(=O)OCC#N nan
CHEMBL1545062 47420 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 2 0 5 1.3 Cc1nc2ccccn2c1C(=O)OCC#N nan
976399 47428 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 4 4.1 Cc1ccc(OC(=O)c2ccc3nc(C)sc3c2)cc1 nan
CHEMBL1545103 47428 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 4 4.1 Cc1ccc(OC(=O)c2ccc3nc(C)sc3c2)cc1 nan
3455851 47526 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 3.2 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(F)cc1 nan
CHEMBL1545899 47526 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 3.2 O=S(=O)(Nc1nc2ccccc2nc1Cl)c1ccc(F)cc1 nan
2431161 47735 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 6 3.6 CC(C)[C@H](NC(=O)c1ccccc1Cl)C(=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
CHEMBL1547817 47735 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 6 1 6 3.6 CC(C)[C@H](NC(=O)c1ccccc1Cl)C(=O)OCc1cc(=O)n2cc(Br)ccc2n1 nan
3111438 47791 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 0 4 3.2 CC(=O)OCCCN1C(=O)c2cccc3cc(Br)cc(c23)C1=O nan
CHEMBL1548381 47791 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 0 4 3.2 CC(=O)OCCCN1C(=O)c2cccc3cc(Br)cc(c23)C1=O nan
24792694 47792 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 6 1.9 Cn1c2ccccc2c2nnc(SCC(=O)NC3CC3)nc21 nan
CHEMBL1548382 47792 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 6 1.9 Cn1c2ccccc2c2nnc(SCC(=O)NC3CC3)nc21 nan
664646 47807 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 3.6 COc1ccc(C(=O)OCc2cc3cccc(C)c3nc2O)cc1 nan
CHEMBL1548510 47807 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 3.6 COc1ccc(C(=O)OCc2cc3cccc(C)c3nc2O)cc1 nan
839503 47828 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 3 3 3.0 O=C(Nc1ccccc1C(=O)O)c1ccc(NC(=O)C2CC2)cc1 nan
CHEMBL1548673 47828 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 3 3 3.0 O=C(Nc1ccccc1C(=O)O)c1ccc(NC(=O)C2CC2)cc1 nan
4839425 47921 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 10 0.2 CN(C)S(=O)(=O)c1cc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1Cl nan
CHEMBL1549482 47921 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 10 0.2 CN(C)S(=O)(=O)c1cc(C(=O)OCCn2cnc3c2c(=O)n(C)c(=O)n3C)ccc1Cl nan
838258 48004 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 1 1 3 3.6 Sc1nc(-c2ccccc2)nc2ccccc12 nan
CHEMBL1550135 48004 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 238 1 1 3 3.6 Sc1nc(-c2ccccc2)nc2ccccc12 nan
2794423 48033 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 2 2.3 NC1=CC(=O)c2cccc3cccc1c23 nan
CHEMBL1550366 48033 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 2 2.3 NC1=CC(=O)c2cccc3cccc1c23 nan
16187761 48057 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 7 2.2 Cc1cc(C)n2nc(C(=O)N3CCCC(CNS(=O)(=O)c4cccs4)C3)cc2n1 nan
CHEMBL1550610 48057 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 7 2.2 Cc1cc(C)n2nc(C(=O)N3CCCC(CNS(=O)(=O)c4cccs4)C3)cc2n1 nan
4969856 48132 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 2 6 2.1 CC(=O)Nc1ccc(Nc2ncnc3c2cnn3C)cc1 nan
CHEMBL1551291 48132 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 2 6 2.1 CC(=O)Nc1ccc(Nc2ncnc3c2cnn3C)cc1 nan
16009663 48135 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 7 4.8 CSc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1551326 48135 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 7 4.8 CSc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)c1 nan
7184893 48211 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 8 3.7 CCCCNc1nc2c(S(=O)(=O)c3ccc(C)cc3)nnn2c2ccsc12 nan
CHEMBL1552371 48211 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 8 3.7 CCCCNc1nc2c(S(=O)(=O)c3ccc(C)cc3)nnn2c2ccsc12 nan
1003444 48222 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 2 5 5.7 Nc1c(C(=O)Nc2ccc(Cl)cc2F)sc2nc(-c3cccs3)ccc12 nan
CHEMBL1552586 48222 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 2 5 5.7 Nc1c(C(=O)Nc2ccc(Cl)cc2F)sc2nc(-c3cccs3)ccc12 nan
1841026 48252 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 0 8 1.6 CCOC(=O)/C(C#N)=C/c1c(N2CCN(CC)CC2)nc2c(C)cccn2c1=O nan
CHEMBL1553005 48252 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 0 8 1.6 CCOC(=O)/C(C#N)=C/c1c(N2CCN(CC)CC2)nc2c(C)cccn2c1=O nan
15988107 48254 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 0 7 3.8 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(Cc2ccccc2)c(=O)c2c1c1cc(OC)ccc1n2C nan
CHEMBL1553031 48254 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 0 7 3.8 CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(Cc2ccccc2)c(=O)c2c1c1cc(OC)ccc1n2C nan
16009750 48258 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 Cc1cccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)c1 nan
CHEMBL1553063 48258 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 Cc1cccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)c1 nan
15988172 48276 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 2 4 2.2 CCCCNC(=O)c1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1 nan
CHEMBL1553275 48276 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 2 4 2.2 CCCCNC(=O)c1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1 nan
135697665 48286 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 9 1.8 O=C(OCc1nc(O)c2sccc2n1)c1cccc(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1553392 48286 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 9 1.8 O=C(OCc1nc(O)c2sccc2n1)c1cccc(S(=O)(=O)N2CCOCC2)c1 nan
5927505 48480 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 7 4.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCCO2 nan
CHEMBL1556043 48480 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 7 4.1 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccc2c(c1)OCCO2 nan
2195056 48513 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 2 4.7 O=C(Nc1ccc(F)cc1)c1ccc(COc2ccccc2)cc1 nan
CHEMBL1556330 48513 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 2 4.7 O=C(Nc1ccc(F)cc1)c1ccc(COc2ccccc2)cc1 nan
5301777 48530 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 2 6 5.9 COC(=O)c1ccccc1NC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)c1ccccc1Cl nan
CHEMBL1556556 48530 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 2 6 5.9 COC(=O)c1ccccc1NC(=O)c1sc2nc(C)cc(C)c2c1NC(=O)c1ccccc1Cl nan
3404081 48553 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2c(C)cc(S)nc2c1 nan
CHEMBL1556798 48553 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 189 0 1 2 3.1 Cc1ccc2c(C)cc(S)nc2c1 nan
1348154 48560 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 4 4.9 O=C(Cc1ccc(Cl)cc1)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 nan
CHEMBL1556858 48560 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 4 4.9 O=C(Cc1ccc(Cl)cc1)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 nan
3708288 48572 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 1 4 7 2.3 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1ccccc1 nan
CHEMBL1556915 48572 7 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 1 4 7 2.3 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1ccccc1 nan
285470 48613 29 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CCNc1nc(Cl)nc(-c2cn(-c3ccccc3)c3ccccc23)n1 nan
CHEMBL1557270 48613 29 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CCNc1nc(Cl)nc(-c2cn(-c3ccccc3)c3ccccc23)n1 nan
16009846 48658 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 8 1.7 COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)c(OC)c1 nan
CHEMBL1557614 48658 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 8 1.7 COc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)c(OC)c1 nan
16010737 48667 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 CCc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(C)cc3)c(=O)c3cccnc32)cc1 nan
CHEMBL1557693 48667 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 6 1 6 3.1 CCc1ccc(NC(=O)Cn2c(=O)n(Cc3ccc(C)cc3)c(=O)c3cccnc32)cc1 nan
3333649 48826 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cccs1 nan
CHEMBL1559037 48826 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cccs1 nan
1166246 48881 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)c(C)c1 nan
CHEMBL1559537 48881 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 5.6 Cc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)c(C)c1 nan
16009080 49084 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 7 1 7 6.7 CCOc1ccc(-c2cc3nc(C4CCN(C(=O)OC(C)(C)C)CC4)c(C(=O)Nc4cccc(CC)c4)cn3n2)cc1 nan
CHEMBL1561508 49084 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 7 1 7 6.7 CCOc1ccc(-c2cc3nc(C4CCN(C(=O)OC(C)(C)C)CC4)c(C(=O)Nc4cccc(CC)c4)cn3n2)cc1 nan
3141845 49142 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 4 6.0 COc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1-c1cc2ccccc2oc1=O nan
CHEMBL1562003 49142 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 4 6.0 COc1cc(NC(=O)c2ccc(Cl)cc2Cl)ccc1-c1cc2ccccc2oc1=O nan
2510921 49248 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 5 2.8 O=C(CNC(=O)C1CCCCC1)OCC(=O)c1ccc(Cl)s1 nan
CHEMBL1562941 49248 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 6 1 5 2.8 O=C(CNC(=O)C1CCCCC1)OCC(=O)c1ccc(Cl)s1 nan
4800554 49370 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 6 3.8 COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc2nc(C)sc2c1 nan
CHEMBL1563979 49370 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 6 1 6 3.8 COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc2nc(C)sc2c1 nan
16009343 49389 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 0 5 4.3 Cc1ccccc1OCc1cc(=O)n2c(-c3ccccc3)csc2n1 nan
CHEMBL1564149 49389 3 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 0 5 4.3 Cc1ccccc1OCc1cc(=O)n2c(-c3ccccc3)csc2n1 nan
4911790 49500 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 1 2 3.4 COc1ccc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2c1 nan
CHEMBL1565220 49500 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 1 2 3.4 COc1ccc2cc(C(=O)N3CCc4ccccc4C3)[nH]c2c1 nan
974361 49556 12 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 3.9 Cc1onc(-c2ccccc2)c1C(=O)Nc1cccc2nsnc12 nan
CHEMBL1565576 49556 12 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 3.9 Cc1onc(-c2ccccc2)c1C(=O)Nc1cccc2nsnc12 nan
15989682 49583 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 1 8 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1565778 49583 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 8 1 8 3.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
1977639 49586 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 5 5.2 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1ccccc1Cl nan
CHEMBL1565785 49586 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 6 1 5 5.2 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1ccccc1Cl nan
789538 49723 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 0 1 4 2.0 CC1=C(C)C(C)=C(C#N)C(=C(C#N)C#N)N1 nan
CHEMBL1566885 49723 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 210 0 1 4 2.0 CC1=C(C)C(C)=C(C#N)C(=C(C#N)C#N)N1 nan
3442888 49829 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 1 0 5 3.1 Cc1cccn2c(=O)c3cc(C(=O)N4CCCC(C)C4)sc3nc12 nan
CHEMBL1567700 49829 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 1 0 5 3.1 Cc1cccn2c(=O)c3cc(C(=O)N4CCCC(C)C4)sc3nc12 nan
16009353 50141 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1C nan
CHEMBL1570398 50141 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 0 5 4.6 Cc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1C nan
16019299 50155 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 1 5 4.2 Cc1cc(C)c(NC(=O)CSc2ccc(-c3ccccn3)nn2)c(C)c1 nan
CHEMBL1570518 50155 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 1 5 4.2 Cc1cc(C)c(NC(=O)CSc2ccc(-c3ccccn3)nn2)c(C)c1 nan
4917201 50227 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 6 1.4 CC(C(=O)Nc1cccnc1)n1cc([N+](=O)[O-])cn1 nan
CHEMBL1571073 50227 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 4 1 6 1.4 CC(C(=O)Nc1cccnc1)n1cc([N+](=O)[O-])cn1 nan
15990163 50229 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 7 3.3 COc1ccc(S(=O)(=O)Nc2cc3c(cc2NCc2ccccc2)n(C)c(=O)n3C)cc1 nan
CHEMBL1571094 50229 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 7 3.3 COc1ccc(S(=O)(=O)Nc2cc3c(cc2NCc2ccccc2)n(C)c(=O)n3C)cc1 nan
16194623 50315 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 0 8 1.8 CC(=O)C(Sc1ccc2nnc(-c3cccnc3)n2n1)C(C)=O nan
CHEMBL1572020 50315 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 0 8 1.8 CC(=O)C(Sc1ccc2nnc(-c3cccnc3)n2n1)C(C)=O nan
135408736 50370 43 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 228 1 1 5 2.1 Sc1ncnc2c1cnn2-c1ccccc1 nan
CHEMBL1572500 50370 43 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 228 1 1 5 2.1 Sc1ncnc2c1cnn2-c1ccccc1 nan
2769007 50687 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 0 7 1.4 CCOC(=O)C(C)Sc1nc(=O)n2cc(C)ccc2n1 nan
CHEMBL1575703 50687 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 0 7 1.4 CCOC(=O)C(C)Sc1nc(=O)n2cc(C)ccc2n1 nan
2808306 50703 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 5 2 4 3.1 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)CCC(=O)O nan
CHEMBL1575844 50703 25 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 5 2 4 3.1 CC(=O)c1sc(C(C)(C)C)cc1NC(=O)CCC(=O)O nan
4356534 50806 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 4.4 COc1ccc2nc(Cl)c(C3CC(c4ccco4)=NN3C(=O)CCCC(=O)O)cc2c1 nan
CHEMBL1576687 50806 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 6 4.4 COc1ccc2nc(Cl)c(C3CC(c4ccco4)=NN3C(=O)CCCC(=O)O)cc2c1 nan
22517522 50930 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 7 2.1 CC(Oc1ccccc1)C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
CHEMBL1577822 50930 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 7 2.1 CC(Oc1ccccc1)C(=O)Nc1nnc(S(=O)(=O)N2CCCCC2)s1 nan
20856926 51120 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 4 3.0 CC(=O)c1cccc(NC(=O)CNC(=O)c2cc3ccccc3o2)c1 nan
CHEMBL1579387 51120 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 5 2 4 3.0 CC(=O)c1cccc(NC(=O)CNC(=O)c2cc3ccccc3o2)c1 nan
4368409 51212 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 8 4.7 CCCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
CHEMBL1580198 51212 17 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 8 4.7 CCCCOc1cccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nnc(C)s2)c1 nan
990451 51277 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 0 7 3.2 Cc1ccc(-n2nc3c(SCCN4CCOCC4)nnc(C)c3c2C)cc1 nan
CHEMBL1580766 51277 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 0 7 3.2 Cc1ccc(-n2nc3c(SCCN4CCOCC4)nnc(C)c3c2C)cc1 nan
661914 51365 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
CHEMBL1581469 51365 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 8 3.7 COc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2cc(C)on2)cc1OC nan
679340 51377 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 2 6 1.8 Cc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)o1 nan
CHEMBL1581638 51377 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 2 6 1.8 Cc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)o1 nan
990454 51396 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 7 3.0 Cc1nnc(SCCN2CCOCC2)c2nn(-c3ccccc3F)c(C)c12 nan
CHEMBL1581794 51396 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 0 7 3.0 Cc1nnc(SCCN2CCOCC2)c2nn(-c3ccccc3F)c(C)c12 nan
2666708 51442 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 7 3.3 COc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc(OC)c1C nan
CHEMBL1582108 51442 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 7 3.3 COc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc(OC)c1C nan
1943119 51719 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 0 10 2.9 COCCn1c(-c2cc(OC)c(OC)c(OC)c2)nc2oc3cc(OC)ccc3c(=O)c2c1=O nan
CHEMBL1584456 51719 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 0 10 2.9 COCCn1c(-c2cc(OC)c(OC)c(OC)c2)nc2oc3cc(OC)ccc3c(=O)c2c1=O nan
5923696 51898 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 1 9 -0.3 N#C/C(=C\c1c(N2CCOCC2)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1 nan
CHEMBL1585817 51898 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 1 9 -0.3 N#C/C(=C\c1c(N2CCOCC2)nc2ccccn2c1=O)C(=O)NC1CCS(=O)(=O)C1 nan
11957204 51945 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 5.1 O=C(Nc1nccs1)c1cc2sccc2n1Cc1ccc(Cl)cc1 nan
CHEMBL1586282 51945 10 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 5 5.1 O=C(Nc1nccs1)c1cc2sccc2n1Cc1ccc(Cl)cc1 nan
2534667 51957 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 0 6 2.4 COc1ccc(C(C)=O)cc1COC(=O)c1cnc(C)cn1 nan
CHEMBL1586370 51957 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 0 6 2.4 COc1ccc(C(C)=O)cc1COC(=O)c1cnc(C)cn1 nan
2048070 51961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 4 4.0 Cc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1C nan
CHEMBL1586414 51961 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 2 4 4.0 Cc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1C nan
4382155 52007 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 6 1 4 2.7 CCc1ccccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
CHEMBL1586776 52007 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 6 1 4 2.7 CCc1ccccc1NC(=O)CCCN1C(=O)c2cccnc2C1=O nan
3548898 52042 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 2 6 1.7 CC(=O)N1CCc2c(sc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)c2C(N)=O)C1 nan
CHEMBL1587022 52042 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 2 6 1.7 CC(=O)N1CCc2c(sc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)c2C(N)=O)C1 nan
3565925 52114 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.9 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC(C)C3 nan
CHEMBL1587609 52114 19 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 1 5 2.9 COCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC(C)C3 nan
661736 52133 14 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 6 3.5 Cc1ccccc1N1C(=O)CC(Sc2nnc(-c3ccccc3)o2)C1=O nan
CHEMBL1587764 52133 14 None -1 3 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 0 6 3.5 Cc1ccccc1N1C(=O)CC(Sc2nnc(-c3ccccc3)o2)C1=O nan
5919084 52186 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 2.9 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(F)cc1)c1ccc2c(c1)OCCO2 nan
CHEMBL1588231 52186 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 2.9 O=C(C1=C(O)C(=O)N(CCCN2CCOCC2)C1c1ccc(F)cc1)c1ccc2c(c1)OCCO2 nan
859793 52214 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 9 -0.6 Cn1c(=O)c2c(nc(SCCN3CCOCC3)n2C)n(C)c1=O nan
CHEMBL1588519 52214 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 9 -0.6 Cn1c(=O)c2c(nc(SCCN3CCOCC3)n2C)n(C)c1=O nan
4203923 52284 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
4573010 52284 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
CHEMBL1589149 52284 15 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 9 1 7 4.4 CCN(CC)CCN1C(=O)C(O)=C(C(=O)c2cc3cccc(OC)c3o2)C1c1cccs1 nan
16016946 52365 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 5 4.5 Cc1c(Cl)cccc1NC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1589855 52365 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 5 4.5 Cc1c(Cl)cccc1NC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O nan
16014998 52367 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2ccc(C)cc2)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1589876 52367 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 5 4.8 CSc1nc(Nc2ccc(C)cc2)c(C#N)c(-c2ccccc2)n1 nan
16017572 52379 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.7 CCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
CHEMBL1589962 52379 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.7 CCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccccc2)s1 nan
16019870 52384 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.8 COc1ccc(OC)c(NC(=O)CSc2cn(CC(=O)N3CCCCCC3)c3ccccc23)c1 nan
CHEMBL1590046 52384 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 6 4.8 COc1ccc(OC)c(NC(=O)CSc2cn(CC(=O)N3CCCCCC3)c3ccccc23)c1 nan
8070199 52396 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 8 1 7 3.5 Cn1nnnc1SCCCNCc1ccc(-c2ccc(Br)cc2)o1 nan
CHEMBL1590182 52396 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 8 1 7 3.5 Cn1nnnc1SCCCNCc1ccc(-c2ccc(Br)cc2)o1 nan
1252599 52415 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 1.9 COC(=O)c1cc(CN2C(=O)c3ccccc3C2=O)c(O)c([N+](=O)[O-])c1 nan
CHEMBL1590469 52415 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 7 1.9 COC(=O)c1cc(CN2C(=O)c3ccccc3C2=O)c(O)c([N+](=O)[O-])c1 nan
3438312 52434 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 5 3.3 COc1ccccc1Cn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
CHEMBL1590737 52434 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 5 2 5 3.3 COc1ccccc1Cn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
8391566 52462 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 0 7 2.5 Cc1nnc(SCc2cc(=O)n3c(C)cccc3n2)s1 nan
CHEMBL1590986 52462 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 0 7 2.5 Cc1nnc(SCc2cc(=O)n3c(C)cccc3n2)s1 nan
16017932 52490 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 1 6 5.8 CCN(CC)c1ccc2cc(-c3nc4sc5c(c4c(=O)[nH]3)CCC(C(C)(C)C)C5)c(=O)oc2c1 nan
CHEMBL1591378 52490 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 4 1 6 5.8 CCN(CC)c1ccc2cc(-c3nc4sc5c(c4c(=O)[nH]3)CCC(C(C)(C)C)C5)c(=O)oc2c1 nan
7152123 52588 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 4.3 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccccc4F)ccc3n2)cc1 nan
CHEMBL1592684 52588 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 4.3 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccccc4F)ccc3n2)cc1 nan
20885677 52612 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 6 1 6 1.3 Cc1nn(CCCC(=O)NCc2ccccc2)c(=O)c2nccn12 nan
CHEMBL1592977 52612 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 6 1 6 1.3 Cc1nn(CCCC(=O)NCc2ccccc2)c(=O)c2nccn12 nan
16403621 52615 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 7 3.0 COc1ccc(OC)c(/C=C2\Oc3cc(OCC(=O)N4CCC(C(=O)O)CC4)ccc3C2=O)c1 nan
CHEMBL1593051 52615 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 7 3.0 COc1ccc(OC)c(/C=C2\Oc3cc(OCC(=O)N4CCC(C(=O)O)CC4)ccc3C2=O)c1 nan
20893093 52624 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 1 7 3.0 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(Cl)c3C)sc2n1 nan
CHEMBL1593179 52624 1 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 3 1 7 3.0 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3cccc(Cl)c3C)sc2n1 nan
16018628 52684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 0 7 5.4 Cc1oc(-c2ccccc2Cl)nc1CSc1nncn2c1cc1occc12 nan
CHEMBL1594061 52684 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 0 7 5.4 Cc1oc(-c2ccccc2Cl)nc1CSc1nncn2c1cc1occc12 nan
16025303 52835 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.2 Cc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1595335 52835 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.2 Cc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
5310070 52843 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 0 8 1.8 CCOC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
CHEMBL1595390 52843 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 0 8 1.8 CCOC(=O)CSc1ccc2nnc(-c3cccnc3)n2n1 nan
15991139 52875 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 0 4 5.2 CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2cccc(C(F)(F)F)c2)o1 nan
CHEMBL1595672 52875 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 0 4 5.2 CCC(C)OC(=O)/C(C#N)=C\c1ccc(-c2cccc(C(F)(F)F)c2)o1 nan
5135766 52967 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 3 5.0 O=C(COc1ccc2oc3c(c2c1)CCCC3)Nc1ccc(Cl)cc1 nan
CHEMBL1596555 52967 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 3 5.0 O=C(COc1ccc2oc3c(c2c1)CCCC3)Nc1ccc(Cl)cc1 nan
3653425 53056 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
661006 53056 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
CHEMBL1597383 53056 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 7 3.7 COC(=O)c1ccc(C2C(C(=O)c3cc4ccccc4o3)=C(O)C(=O)N2CCCN(C)C)cc1 nan
2991609 53060 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 7 2 4 1.6 Cc1ccc(OCC(=O)NCCNC(=O)c2cccnc2)cc1C nan
CHEMBL1597415 53060 16 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 7 2 4 1.6 Cc1ccc(OCC(=O)NCCNC(=O)c2cccnc2)cc1C nan
20893092 53119 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.4 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3ccccc3C)sc2n1 nan
CHEMBL1597947 53119 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.4 Cc1cc(=O)n2nc(N3CCCC3C(=O)Nc3ccccc3C)sc2n1 nan
44666769 53141 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
5289738 53141 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
CHEMBL1598157 53141 22 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 6 0.9 Cc1cc(=O)oc2c(CN3CCN(CCO)CC3)c(O)ccc12 nan
5310246 53152 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.0 COc1ccc(-c2cn3c(C)c(C(=O)Nc4ccncc4)sc3n2)cc1 nan
CHEMBL1598249 53152 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.0 COc1ccc(-c2cn3c(C)c(C(=O)Nc4ccncc4)sc3n2)cc1 nan
2807627 53208 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 1 0 5 1.4 CC1CCCN(c2ccc3nncn3n2)C1 nan
CHEMBL1598761 53208 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 217 1 0 5 1.4 CC1CCCN(c2ccc3nncn3n2)C1 nan
22514515 53292 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 0 7 0.9 CCOC(=O)C1CCN(C(=O)Cn2nc(CC)n3cccc3c2=O)CC1 nan
CHEMBL1599442 53292 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 0 7 0.9 CCOC(=O)C1CCN(C(=O)Cn2nc(CC)n3cccc3c2=O)CC1 nan
2913046 53478 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 5.1 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)c(Cl)c2)o1 nan
CHEMBL1601179 53478 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 5 5.1 Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccc(Cl)c(Cl)c2)o1 nan
3152554 53505 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.3 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1Cl)c1ccco1 nan
CHEMBL1601448 53505 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.3 O=C(C1=C(O)C(=O)N(CC2CCCO2)C1c1ccc(Cl)cc1Cl)c1ccco1 nan
3733422 53552 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.2 COc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
CHEMBL1602024 53552 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 4.2 COc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1 nan
3185717 53555 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 8 3.2 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1C nan
CHEMBL1602063 53555 5 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 9 3 8 3.2 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1C nan
1541054 53883 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 5 4.3 CCOc1cccc(NC(=O)CSc2nc(C)c3c(c2C#N)CCCC3)c1 nan
CHEMBL1604887 53883 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 5 4.3 CCOc1cccc(NC(=O)CSc2nc(C)c3c(c2C#N)CCCC3)c1 nan
20885689 53948 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
CHEMBL1605440 53948 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 7 1.3 COc1ccc(CNC(=O)CCCn2nc(C)n3ccnc3c2=O)cc1 nan
2890303 54049 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 2.7 CC(=O)C1=C(O)C(=O)N(c2ccccn2)C1c1cccc(F)c1 nan
CHEMBL1606210 54049 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 2.7 CC(=O)C1=C(O)C(=O)N(c2ccccn2)C1c1cccc(F)c1 nan
16030495 54090 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 5.9 Cc1ccc(Cl)cc1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
CHEMBL1606531 54090 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 5.9 Cc1ccc(Cl)cc1NC(=O)CSc1nc2ccccc2nc1Cc1ccccc1 nan
855274 54222 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 0 5 2.0 COc1ccc2cc(C#N)c(N3CCOCC3)nc2c1 nan
CHEMBL1607471 54222 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 0 5 2.0 COc1ccc2cc(C#N)c(N3CCOCC3)nc2c1 nan
3663093 54246 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.6 CCc1nnc(NC(=O)CSc2nc3c([nH]c4ccccc43)c(=O)n2-c2cc(C)cc(C)c2)s1 nan
CHEMBL1607685 54246 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.6 CCc1nnc(NC(=O)CSc2nc3c([nH]c4ccccc43)c(=O)n2-c2cc(C)cc(C)c2)s1 nan
889917 54347 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 5 1 3 3.7 CCc1c(SCCC(=O)O)nc2ccccc2c1C nan
CHEMBL1608598 54347 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 5 1 3 3.7 CCc1c(SCCC(=O)O)nc2ccccc2c1C nan
7120053 54498 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
CHEMBL1609827 54498 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 1 1 4 4.1 Cc1cccc(-n2c(=S)[nH]c3c(oc4ccccc43)c2=O)c1 nan
2371304 54537 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 6 2.8 O=C(CSc1ncnc2ccccc12)NCc1ccc2c(c1)OCO2 nan
CHEMBL1610145 54537 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 6 2.8 O=C(CSc1ncnc2ccccc12)NCc1ccc2c(c1)OCO2 nan
4380426 54584 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1nnc(-c2ccccc2Cl)s1)c1ccccc1F nan
CHEMBL1610533 54584 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1nnc(-c2ccccc2Cl)s1)c1ccccc1F nan
2813334 54668 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 6 3.2 CCOC(=O)C1CCCN(C(=O)c2csc(-c3ccc4c(c3)CCO4)n2)C1 nan
CHEMBL1611317 54668 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 6 3.2 CCOC(=O)C1CCCN(C(=O)c2csc(-c3ccc4c(c3)CCO4)n2)C1 nan
16014906 54714 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc(CNC(=O)c2cc3cc(C)ccc3n2C)cc1 nan
CHEMBL1611737 54714 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc(CNC(=O)c2cc3cc(C)ccc3n2C)cc1 nan
4853715 54725 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.6 CC(=O)c1sc(NC(=O)c2cnc(Cl)c(Cl)c2)nc1C nan
CHEMBL1611812 54725 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.6 CC(=O)c1sc(NC(=O)c2cnc(Cl)c(Cl)c2)nc1C nan
16009370 54738 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 0 5 5.3 O=c1cc(COc2ccc(Cl)cc2Cl)nc2scc(-c3ccccc3)n12 nan
CHEMBL1611935 54738 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 0 5 5.3 O=c1cc(COc2ccc(Cl)cc2Cl)nc2scc(-c3ccccc3)n12 nan
24892471 55035 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
CHEMBL1356182 55035 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
CHEMBL1616404 55035 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 9 1 5 6.4 CCCCNc1c(-c2ccc(SC(C)CC)c(OC)c2)nc2ccc(C)cn12 nan
24789689 55395 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
CHEMBL1395742 55395 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
CHEMBL1619301 55395 0 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 2 4 3.3 CC(=O)Nc1ccc(-c2sc(Nc3ccccc3)n[n+]2C)cc1 nan
6489920 55542 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1428082 55542 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
CHEMBL1620517 55542 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 264 3 0 2 3.1 CCn1c(/C=C/c2cc[n+](C)cc2)nc2ccccc21 nan
5064206 55590 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
CHEMBL1455685 55590 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
CHEMBL1621049 55590 7 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.9 Cc1cc[n+]2cc(-c3cccc([N+](=O)[O-])c3)c(-c3cccc([N+](=O)[O-])c3)cc2c1 nan
820476 55844 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
CHEMBL1522563 55844 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
CHEMBL1623170 55844 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 195 0 1 1 2.2 Nc1ccc2ccc3cccc[n+]3c2c1 nan
1560419 55848 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
CHEMBL1517106 55848 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
CHEMBL1623202 55848 18 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 7 2 4 3.4 O=C(O)CCCCCNc1ncnc2ccc(Br)cc12 nan
1567753 55860 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
CHEMBL1534121 55860 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
CHEMBL1623318 55860 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 7 1 5 3.7 COc1ccc(-c2nc(NCCCN(C)C)c3ccccc3n2)cc1 nan
818329 56025 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
CHEMBL1568356 56025 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
CHEMBL1624703 56025 28 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 4 4.0 Sc1nnc(-c2ccc(Br)cc2)n1-c1ccccc1 nan
3146476 69811 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
5767654 69811 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
6248042 69811 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
CHEMBL193627 69811 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
CHEMBL584458 69811 5 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 0 2 4.9 CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2cccc(C)c21 nan
2152519 71987 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 7 0 9 3.6 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1ccccc1OCC nan
CHEMBL1973861 71987 11 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 7 0 9 3.6 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N/C(=O)c1ccccc1OCC nan
2003230 72241 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 0 8 1.2 CCOC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CCOC)/c1=N\C(C)=O nan
CHEMBL1981685 72241 13 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 0 8 1.2 CCOC(=O)c1cc2c(=O)n3cccc(C)c3nc2n(CCOC)/c1=N\C(C)=O nan
9580624 72390 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 6 1 7 2.5 COc1cccc(/C=N/Nc2ncccc2[N+](=O)[O-])c1OC nan
CHEMBL1986514 72390 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 6 1 7 2.5 COc1cccc(/C=N/Nc2ncccc2[N+](=O)[O-])c1OC nan
9564678 72534 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1991163 72534 12 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 9 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 nan
135406177 72558 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 2 2 4 3.6 Cc1ccc(O)c(/N=C/C2=C(O)c3ccccc3C2=O)c1 nan
CHEMBL1991885 72558 6 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 2 2 4 3.6 Cc1ccc(O)c(/N=C/C2=C(O)c3ccccc3C2=O)c1 nan
9583975 72645 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 2 6 5.8 Nc1c(C(=O)N/N=C/c2ccccc2Cl)oc2nc(-c3ccccc3)cc(-c3ccco3)c12 nan
CHEMBL1995041 72645 2 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 2 6 5.8 Nc1c(C(=O)N/N=C/c2ccccc2Cl)oc2nc(-c3ccccc3)cc(-c3ccco3)c12 nan
5936993 72816 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 0 2 6.9 CCN(CC)c1ccc(/C=C/c2cc(-c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL2001294 72816 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 0 2 6.9 CCN(CC)c1ccc(/C=C/c2cc(-c3ccccc3)c3ccccc3n2)cc1 nan
735993 88010 41 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.1 CN(C)c1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
CHEMBL234378 88010 41 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 2 1 4 3.1 CN(C)c1ccc(-c2nc3cc(N)ccc3o2)cc1 nan
9638128 107753 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 7 0 5 3.4 CCN(CC)c1ccc(C(=O)c2cnc(/N=C/N(C)C)s2)cc1 nan
CHEMBL3191439 107753 14 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 7 0 5 3.4 CCN(CC)c1ccc(C(=O)c2cnc(/N=C/N(C)C)s2)cc1 nan
24892228 107857 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 0 8 2.7 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3192568 107857 9 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 9 0 8 2.7 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
46497908 108017 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 10 0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C\c2ccccc2[N+](=O)[O-])n(C)c1=O nan
CHEMBL3194459 108017 4 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 10 0.2 Cn1c(=O)c2c(ncn2CC(=O)N/N=C/C=C\c2ccccc2[N+](=O)[O-])n(C)c1=O nan
135412189 108242 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 3 10 1.0 COc1cc(/C=N/Nc2nc(O)nnc2C)cc([N+](=O)[O-])c1O nan
CHEMBL3197005 108242 11 None -2 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 3 10 1.0 COc1cc(/C=N/Nc2nc(O)nnc2C)cc([N+](=O)[O-])c1O nan
4122444 108506 11 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 2.4 CCOC(=O)c1s/c(=N\C(=O)c2cccs2)n(C)c1C nan
CHEMBL3199794 108506 11 None -8 2 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 6 2.4 CCOC(=O)c1s/c(=N\C(=O)c2cccs2)n(C)c1C nan
5343366 108511 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 4 0 7 1.8 CSc1nncn1/N=C/c1ccc([N+](=O)[O-])cc1 nan
CHEMBL3199842 108511 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 4 0 7 1.8 CSc1nncn1/N=C/c1ccc([N+](=O)[O-])cc1 nan
135411619 108521 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 4 1 8 1.5 Cc1nn(-c2ccc([N+](=O)[O-])cc2)c(O)c1/C=N/N1CCOCC1 nan
CHEMBL3199911 108521 8 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 4 1 8 1.5 Cc1nn(-c2ccc([N+](=O)[O-])cc2)c(O)c1/C=N/N1CCOCC1 nan
9955 142337 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
CHEMBL1356616 142337 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
CHEMBL388594 142337 101 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 135 0 2 4 -0.1 Nc1nc2ncnc-2c[nH]1 nan
154730799 167676 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
65191 167676 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
CHEMBL1306565 167676 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
CHEMBL4302011 167676 44 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 8 1 7 4.0 CCN(CC)c1ccc2c(-c3ccc(S(=O)(=O)O)cc3S(=O)(=O)[O-])c3ccc(=[N+](CC)CC)cc-3oc2c1 nan
21551 184250 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 2 0 6 0.6 Cn1c(=O)c2c(nc(Cc3ccccc3)n2C)n(C)c1=O nan
CHEMBL483661 184250 6 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 284 2 0 6 0.6 Cn1c(=O)c2c(nc(Cc3ccccc3)n2C)n(C)c1=O nan
4380636 201006 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 5.3 CC(C)c1ccc(Nc2c(-c3ccccn3)nc3ccccn23)cc1 nan
CHEMBL602150 201006 10 None - 1 Human 4.6 pPotency = 4.6 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 5.3 CC(C)c1ccc(Nc2c(-c3ccccn3)nc3ccccn23)cc1 nan
1499 2091 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3779 2091 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
536 2091 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
CHEMBL434 2091 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
DB01064 2091 47 None -31622 38 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(NCC(c1ccc(c(c1)O)O)O)C nan
3762 14472 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
CHEMBL1201153 14472 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
CHEMBL1201213 14472 27 None 1 3 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 5 4 4 1.9 CCC(NC(C)C)C(O)c1ccc(O)c(O)c1 nan
1214032 19762 13 None -2 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 6 1 7 6.1 CC1(C)Cc2nc3sc4c(SCC(=O)NC(c5ccccc5)c5ccccc5)ncnc4c3cc2CO1 nan
CHEMBL1301335 19762 13 None -2 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 6 1 7 6.1 CC1(C)Cc2nc3sc4c(SCC(=O)NC(c5ccccc5)c5ccccc5)ncnc4c3cc2CO1 nan
15990933 21773 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 3 6.2 CC(C)c1ccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)cc1 nan
CHEMBL1319127 21773 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 3 6.2 CC(C)c1ccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)cc1 nan
1716420 22072 14 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 5 6.5 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(C(F)(F)F)c4)c(Br)c3n2)cc1 nan
CHEMBL1321710 22072 14 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 558 4 1 5 6.5 COc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)Nc4cccc(C(F)(F)F)c4)c(Br)c3n2)cc1 nan
2919028 24373 15 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 10 3.9 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OC)c(OC)c2)nc1C nan
CHEMBL1341127 24373 15 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 10 3.9 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(OC)c(OC)c2)nc1C nan
16019314 30900 12 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 5 1 9 4.9 COc1ccc(C)cc1Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
CHEMBL1397774 30900 12 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 5 1 9 4.9 COc1ccc(C)cc1Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
944832 31560 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 0 2 3 3.0 Sc1[nH]cnc2c3cc(Cl)ccc3nc1-2 nan
CHEMBL1404042 31560 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 0 2 3 3.0 Sc1[nH]cnc2c3cc(Cl)ccc3nc1-2 nan
4024853 31701 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.6 CCCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc(N(C)C)cc4)nc3c2)cc1 nan
CHEMBL1405437 31701 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.6 CCCOc1ccc(C(=O)Nc2ccc3oc(-c4ccc(N(C)C)cc4)nc3c2)cc1 nan
24892224 34104 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 9 0.5 CC(C)c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1425449 34104 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 9 0.5 CC(C)c1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16033262 36273 1 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 1 5 5.9 Cc1c(C(=O)Nc2ccc(Br)cc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
CHEMBL1445708 36273 1 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 1 5 5.9 Cc1c(C(=O)Nc2ccc(Br)cc2F)sc2ncnc(N(C)C3CCCCC3)c12 nan
4179349 39595 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 8 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1473745 39595 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 8 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3ccc(OC)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
2810065 42959 6 None 1 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 2 1 5 4.0 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)c1ccco1 nan
CHEMBL1503612 42959 6 None 1 2 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 2 1 5 4.0 O=C(Nc1nc2c(Br)cc(Br)cc2c(=O)s1)c1ccco1 nan
16019583 44088 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 4 0 9 3.1 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
CHEMBL1514816 44088 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 4 0 9 3.1 CCN1CCN(c2nc3c(S(=O)(=O)c4ccc(Br)cc4)nnn3c3ccsc23)CC1 nan
16023031 44622 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 3.1 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(F)cc3)s2)cc1 nan
CHEMBL1520434 44622 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 3.1 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(F)cc3)s2)cc1 nan
16030551 48122 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 4 5.1 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
CHEMBL1551173 48122 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 8 1 4 5.1 CC(C)CCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
16009713 53978 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(-c2nnn3c2nc(NCc2ccc(C)cc2)c2ccccc23)cc1 nan
CHEMBL1605623 53978 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 4.9 COc1ccc(-c2nnn3c2nc(NCc2ccc(C)cc2)c2ccccc23)cc1 nan
49858523 89534 0 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 0 5 5.0 CCCC[C@]12Cc3cc(C#N)ccc3[C@H](O1)c1c(cc(C)n(Cc3ccccc3)c1=O)O2 nan
CHEMBL2373613 89534 0 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 0 5 5.0 CCCC[C@]12Cc3cc(C#N)ccc3[C@H](O1)c1c(cc(C)n(Cc3ccccc3)c1=O)O2 nan
16010255 5972 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.1 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccc(Cl)cc23)c(C)c1 nan
CHEMBL1079970 5972 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 7 5.1 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccc(Cl)cc23)c(C)c1 nan
16010278 6131 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 7 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1cc(Cl)ccc12 nan
CHEMBL1080898 6131 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 7 4.4 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1cc(Cl)ccc12 nan
18560284 6346 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 7 1 8 3.3 O=C1CCCN1CCCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccccc12 nan
CHEMBL1082027 6346 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 7 1 8 3.3 O=C1CCCN1CCCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccccc12 nan
16010337 6384 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 4.1 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2cc(Cl)ccc23)cc1 nan
CHEMBL1082207 6384 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 4.1 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2cc(Cl)ccc23)cc1 nan
7185123 10677 6 None -851 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
CHEMBL1170673 10677 6 None -851 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 1 8 3.9 O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
16019553 10706 6 None -912 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 8 4.4 CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 nan
CHEMBL1170871 10706 6 None -912 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 8 4.4 CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 nan
16019312 10898 1 None -144 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 9 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1172727 10898 1 None -144 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 9 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
4968664 19699 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3cc(C)ccc3C)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1300883 19699 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 2 6 6.2 COc1cc(C(=O)Nc2nc(-c3cc(C)ccc3C)c(C)s2)ccc1OCC(=O)Nc1ccc(F)cc1 nan
16435505 19735 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CC3CCCO3)c(=O)n2c1 nan
CHEMBL1301161 19735 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 2 8 1.5 Cc1ccc2nc3c(cc(C(=O)NCC4CCCO4)c(=N)n3CC3CCCO3)c(=O)n2c1 nan
1451395 19761 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.6 Cc1cccc(NC(=O)CSc2nc(COc3ccccc3)nc3ccccc23)c1C nan
CHEMBL1301326 19761 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 5 5.6 Cc1cccc(NC(=O)CSc2nc(COc3ccccc3)nc3ccccc23)c1C nan
1019237 19922 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 6 2 5 3.6 COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)n1 nan
CHEMBL1302646 19922 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 6 2 5 3.6 COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)n1 nan
1176215 20105 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 7 3.7 CCc1nnc(NC(=O)CSc2nc3cc(OC)ccc3cc2C)s1 nan
CHEMBL1304139 20105 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 7 3.7 CCc1nnc(NC(=O)CSc2nc3cc(OC)ccc3cc2C)s1 nan
706653 20111 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 5 3.5 N#Cc1c(-c2ccccc2)c(C#N)c2nc3ccccc3n2c1N nan
CHEMBL1304187 20111 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 5 3.5 N#Cc1c(-c2ccccc2)c(C#N)c2nc3ccccc3n2c1N nan
2060107 20157 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.7 COc1ccc(NC(=O)CSc2nnc(-c3cccs3)n2-c2ccccc2)cc1 nan
CHEMBL1304585 20157 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 7 1 7 4.7 COc1ccc(NC(=O)CSc2nnc(-c3cccs3)n2-c2ccccc2)cc1 nan
16034541 20368 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 6 3.5 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Br)s1 nan
CHEMBL1306241 20368 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 6 1 6 3.5 CN(Cc1ccc(F)cc1)S(=O)(=O)c1nnc(NC(=O)c2ccccc2Br)s1 nan
12005386 20450 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 6 4.7 CCCCOc1ccc(C(=O)Nn2c(-c3cccs3)nc3ccccc3c2=O)cc1 nan
CHEMBL1306967 20450 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 6 4.7 CCCCOc1ccc(C(=O)Nn2c(-c3cccs3)nc3ccccc3c2=O)cc1 nan
24818410 20702 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 6 0 6 4.2 COc1cccc(COC(=O)c2c(C)nn(-c3ccccc3)c2Cl)c1OC nan
CHEMBL1308959 20702 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 6 0 6 4.2 COc1cccc(COC(=O)c2c(C)nn(-c3ccccc3)c2Cl)c1OC nan
2081889 20975 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(Cc3ccccc3)c(=O)c2c1C nan
CHEMBL1311321 20975 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(Cc3ccccc3)c(=O)c2c1C nan
2102674 21001 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 3.6 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(F)cc2)no1 nan
CHEMBL1311532 21001 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 3.6 Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2ccc(F)cc2)no1 nan
651309 21339 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
CHEMBL1314039 21339 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
16028453 21406 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 3 4 5.4 CCc1ccccc1NC(=O)Nc1cc(C(=O)NCc2ccc(OC)cc2)ccc1N1CCCC1 nan
CHEMBL1314777 21406 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 3 4 5.4 CCc1ccccc1NC(=O)Nc1cc(C(=O)NCc2ccc(OC)cc2)ccc1N1CCCC1 nan
15990013 21419 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 2 8 3.4 COc1ccccc1CNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1314976 21419 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 2 8 3.4 COc1ccccc1CNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
16025439 21440 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 7 1 6 4.6 Cc1ccccc1CN1c2ccccc2-c2nc(SCC(=O)NCc3ccccc3)ncc2S1(=O)=O nan
CHEMBL1315303 21440 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 7 1 6 4.6 Cc1ccccc1CN1c2ccccc2-c2nc(SCC(=O)NCc3ccccc3)ncc2S1(=O)=O nan
18579745 21462 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 2.9 CCOC(=O)c1nn(-c2ccc(F)cc2)c(=O)cc1OCC(=O)Nc1cccc(C)c1 nan
CHEMBL1315496 21462 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 2.9 CCOC(=O)c1nn(-c2ccc(F)cc2)c(=O)cc1OCC(=O)Nc1cccc(C)c1 nan
135455826 21513 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 1 5 4.9 Cc1ccc(-c2cc(C(F)F)nc3sc4c(O)ncnc4c23)cc1 nan
CHEMBL1316104 21513 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 2 1 5 4.9 Cc1ccc(-c2cc(C(F)F)nc3sc4c(O)ncnc4c23)cc1 nan
16008870 21527 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 2 1 4 3.9 Cn1c(C(=O)Nc2cccc(Cl)c2)cc2c(=O)n(C)c3ccccc3c21 nan
CHEMBL1316241 21527 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 2 1 4 3.9 Cn1c(C(=O)Nc2cccc(Cl)c2)cc2c(=O)n(C)c3ccccc3c21 nan
16024585 21532 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1316336 21532 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
16023032 21536 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 2 5 4.7 CC(=O)c1ccc(NC(=O)c2cccc(NC(=O)N3CCSc4ncccc43)c2)cc1 nan
CHEMBL1316423 21536 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 2 5 4.7 CC(=O)c1ccc(NC(=O)c2cccc(NC(=O)N3CCSc4ncccc43)c2)cc1 nan
937929 21549 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 4 3.6 Cc1nc(N)c(C#N)c(-c2cccnc2)c1-c1ccccc1 nan
CHEMBL1316609 21549 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 4 3.6 Cc1nc(N)c(C#N)c(-c2cccnc2)c1-c1ccccc1 nan
16009522 21586 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4)cc3)cc(=O)n12 nan
CHEMBL1317126 21586 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4)cc3)cc(=O)n12 nan
16020239 21651 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 6 1 5 5.2 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(Cc3cccc(F)c3)c2=O)cc1 nan
CHEMBL1317963 21651 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 527 6 1 5 5.2 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(Cc3cccc(F)c3)c2=O)cc1 nan
16022974 21652 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.8 Cc1nnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1317977 21652 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 5 1 6 4.8 Cc1nnc(N2CCC(C(=O)NCc3ccc(F)cc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
3450154 21688 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.6 CC(=O)c1sc(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2F)nc1C nan
CHEMBL1318435 21688 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 6 2.6 CC(=O)c1sc(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2F)nc1C nan
15988872 21689 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 5.4 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Cl)cc3)on2)sc2c1CCCC2 nan
CHEMBL1318439 21689 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 5 1 6 5.4 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Cl)cc3)on2)sc2c1CCCC2 nan
16008607 21692 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 6 1.6 Cc1nc2c(c(C)c1CCC(=O)NCc1ccc(F)cc1)c(=O)n(C)c(=O)n2C nan
CHEMBL1318457 21692 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 5 1 6 1.6 Cc1nc2c(c(C)c1CCC(=O)NCc1ccc(F)cc1)c(=O)n(C)c(=O)n2C nan
15991398 21710 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 4 6.3 Cc1ccc(NC(=O)c2cc3c(-c4ccccc4)nn(-c4ccccc4)c3s2)cc1 nan
CHEMBL1318575 21710 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 4 1 4 6.3 Cc1ccc(NC(=O)c2cc3c(-c4ccccc4)nn(-c4ccccc4)c3s2)cc1 nan
3144686 21737 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 4 4.3 CCC(C)NC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 nan
CHEMBL1318807 21737 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 4 4.3 CCC(C)NC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 nan
1329083 21783 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 4 4.7 Cc1cccc(C)c1NC(=O)COc1ccccc1C(=O)Nc1ccc(Br)cn1 nan
CHEMBL1319204 21783 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 2 4 4.7 Cc1cccc(C)c1NC(=O)COc1ccccc1C(=O)Nc1ccc(Br)cn1 nan
1983515 21811 8 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 1 6 5.3 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccs1 nan
CHEMBL1319447 21811 8 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 6 1 6 5.3 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)cc1)c1cccs1 nan
20889080 21857 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 4.1 CC(CNc1nc2ccc(Cl)cc2n2cnnc12)c1ccccc1 nan
CHEMBL1319804 21857 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 4.1 CC(CNc1nc2ccc(Cl)cc2n2cnnc12)c1ccccc1 nan
16017559 21963 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCC(C)CC3)s2)c1 nan
CHEMBL1320668 21963 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 2.5 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N3CCC(C)CC3)s2)c1 nan
16029569 22101 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 5 4.5 Cc1cc2c(=O)c(C(=O)c3ccncc3)cn(CC(=O)Nc3cccc(C)c3C)c2cc1C nan
CHEMBL1321921 22101 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 5 4.5 Cc1cc2c(=O)c(C(=O)c3ccncc3)cn(CC(=O)Nc3cccc(C)c3C)c2cc1C nan
15989030 22133 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 3.9 Cc1ccc(CNC(=O)CCCn2c(=O)c3sccc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
CHEMBL1322214 22133 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 3.9 Cc1ccc(CNC(=O)CCCn2c(=O)c3sccc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
4412940 22198 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 5.1 CCOc1ccc(-n2cc(C(=O)Nc3ccccc3OCC)c3cc(OC)c(OC)cc3c2=O)cc1 nan
CHEMBL1322786 22198 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 9 1 7 5.1 CCOc1ccc(-n2cc(C(=O)Nc3ccccc3OCC)c3cc(OC)c(OC)cc3c2=O)cc1 nan
3197538 22246 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 5.3 CCCc1nc(SCC(=O)N2c3ccccc3CC2C)c2c(C)c(C)sc2n1 nan
CHEMBL1323376 22246 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 0 5 5.3 CCCc1nc(SCC(=O)N2c3ccccc3CC2C)c2c(C)c(C)sc2n1 nan
3223224 22375 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.5 Cc1ccnc(N2CCC(C(=O)NCc3ccccc3F)CC2)n1 nan
CHEMBL1324395 22375 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.5 Cc1ccnc(N2CCC(C(=O)NCc3ccccc3F)CC2)n1 nan
16025301 22386 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 594 8 1 8 5.4 CCOC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1324479 22386 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 594 8 1 8 5.4 CCOC(=O)c1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
24818748 22429 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 3 5 3.9 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)c(OC)c1 nan
CHEMBL1324786 22429 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 3 5 3.9 COc1ccc(NC(=O)NNC(=O)COc2ccc3cc(Br)ccc3c2)c(OC)c1 nan
15991180 22504 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 4 6.4 CCOc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4cc(C)cc(C)c4o3)c2)cc1 nan
CHEMBL1325481 22504 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 4 6.4 CCOc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4cc(C)cc(C)c4o3)c2)cc1 nan
794333 22628 61 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 0 2 3.7 COc1ccc(C(=O)c2ccc(Br)cc2)cc1 nan
CHEMBL1326786 22628 61 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 0 2 3.7 COc1ccc(C(=O)c2ccc(Br)cc2)cc1 nan
16012102 22650 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
CHEMBL1326931 22650 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 4 1 7 3.2 CCc1cccc(C)c1NC(=O)C1CCN(c2nn3c(=O)cc(C)nc3s2)CC1 nan
2097459 22666 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1ccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)cc1Cl nan
CHEMBL1327066 22666 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 3 1 3 4.1 Cc1ccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)cc1Cl nan
15988236 22687 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 7 2.1 CCC(C)NC(=O)Cn1c(=O)n(-c2cc(OC)cc(OC)c2)c(=O)c2ccccc21 nan
CHEMBL1327218 22687 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 7 2.1 CCC(C)NC(=O)Cn1c(=O)n(-c2cc(OC)cc(OC)c2)c(=O)c2ccccc21 nan
6825246 22724 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 8 2 8 1.9 CCOc1ccc(-n2c([S-])c(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)[n+]3cc(C(N)=O)ccc23)cc1 nan
CHEMBL1327580 22724 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 8 2 8 1.9 CCOc1ccc(-n2c([S-])c(C(=O)Nc3ccc(S(=O)(=O)N4CCOCC4)cc3)[n+]3cc(C(N)=O)ccc23)cc1 nan
3192843 22756 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 6 2.8 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccccc2F)n1)NC1CCCC1 nan
CHEMBL1327798 22756 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 2 6 2.8 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccccc2F)n1)NC1CCCC1 nan
2816102 22818 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 2 0 5 3.3 CCOc1ncnc2c1sc1nc(C)cc(C)c12 nan
CHEMBL1328179 22818 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 259 2 0 5 3.3 CCOc1ncnc2c1sc1nc(C)cc(C)c12 nan
16009635 22964 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 8 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1OC nan
CHEMBL1329536 22964 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 8 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1OC nan
753116 23025 57 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 3 4.3 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)o1 nan
CHEMBL1330042 23025 57 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 2 1 3 4.3 Cc1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)o1 nan
4246541 23134 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 4 4.9 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3ccc(Br)cc3F)c(C)c2c1 nan
CHEMBL1330918 23134 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 4 4.9 CCN(CC)S(=O)(=O)c1ccc2oc(C(=O)Nc3ccc(Br)cc3F)c(C)c2c1 nan
701957 23200 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 3 3.4 CCOc1cc(C)cc2oc(=O)c3c(c12)CCCC3 nan
CHEMBL1331353 23200 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 2 0 3 3.4 CCOc1cc(C)cc2oc(=O)c3c(c12)CCCC3 nan
16014559 23201 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.9 COc1ccc(-c2nc3nc(C)cc(Nc4cccc(C(F)(F)F)c4)n3n2)cc1 nan
CHEMBL1331359 23201 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 6 4.9 COc1ccc(-c2nc3nc(C)cc(Nc4cccc(C(F)(F)F)c4)n3n2)cc1 nan
16009329 23276 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 1 7 3.3 O=C(Cn1cc(S(=O)(=O)c2ccc(F)cc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
CHEMBL1331963 23276 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 1 7 3.3 O=C(Cn1cc(S(=O)(=O)c2ccc(F)cc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
2151601 23323 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1332323 23323 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
5310234 23416 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 8 2.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)NCc1ccco1 nan
CHEMBL1333013 23416 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 1 8 2.2 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)NCc1ccco1 nan
16018028 23535 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 4 2.6 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccccc1 nan
CHEMBL1333957 23535 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 4 2.6 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccccc1 nan
3174233 23593 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 10 3 7 3.1 CCCCOc1ccc(N(CC(=O)NC2CCCCC2)C(=O)c2snc(C(N)=O)c2N)cc1 nan
CHEMBL1334365 23593 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 10 3 7 3.1 CCCCOc1ccc(N(CC(=O)NC2CCCCC2)C(=O)c2snc(C(N)=O)c2N)cc1 nan
2237458 23601 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.3 COCc1cc(C)nc(SCC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1C#N nan
CHEMBL1334406 23601 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.3 COCc1cc(C)nc(SCC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1C#N nan
16030555 23657 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 5.9 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCCc2ccccc21 nan
CHEMBL1334948 23657 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 5.9 O=C(CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1)N1CCCc2ccccc21 nan
1257917 23677 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 1 4 3.0 O=C(Nc1ccc(F)cc1F)c1cc2ncc(Br)cn2n1 nan
CHEMBL1335101 23677 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 1 4 3.0 O=C(Nc1ccc(F)cc1F)c1cc2ncc(Br)cn2n1 nan
16010812 23709 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 0 7 3.8 Fc1ccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)cc1 nan
CHEMBL1335280 23709 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 0 7 3.8 Fc1ccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)cc1 nan
16015336 23738 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccc5c(c4)OCO5)c3C)nc2C)cc1 nan
CHEMBL1335512 23738 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccc(NC(=O)c2sc(-n3nc(C)c(Cc4ccc5c(c4)OCO5)c3C)nc2C)cc1 nan
1450291 23815 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
CHEMBL1336163 23815 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 6 3.8 Cc1cc(C)c2cc(C#N)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
5115564 23819 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 3 7 5.7 N#Cc1ccccc1NC(=O)C1SC(Nc2ccccc2)=C(c2nc3ccccc3s2)C1=N nan
CHEMBL1336187 23819 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 3 7 5.7 N#Cc1ccccc1NC(=O)C1SC(Nc2ccccc2)=C(c2nc3ccccc3s2)C1=N nan
1366812 24158 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 4 5.3 Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)COc1ccccc1 nan
CHEMBL1339140 24158 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 4 5.3 Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)COc1ccccc1 nan
1860843 24285 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 2 5 5.2 Nc1c(C(=O)Nc2ccc(Br)cc2)sc2nc(-c3ccco3)ccc12 nan
CHEMBL1340363 24285 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 2 5 5.2 Nc1c(C(=O)Nc2ccc(Br)cc2)sc2nc(-c3ccco3)ccc12 nan
1258323 24351 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 2 6 3.6 Nc1c(C(=O)NCCc2ccccc2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
CHEMBL1340956 24351 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 2 6 3.6 Nc1c(C(=O)NCCc2ccccc2)sc2nc(N3CCOCC3)c3c(c12)CCCC3 nan
1248113 24363 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 0 7 3.3 CCOC(=O)c1cc(OC(=O)c2cccs2)n(-c2ccccc2)n1 nan
CHEMBL1341066 24363 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 0 7 3.3 CCOC(=O)c1cc(OC(=O)c2cccs2)n(-c2ccccc2)n1 nan
2478762 24611 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 3.3 Cc1c(C(=O)OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2c1ccc1ccccc12 nan
CHEMBL1343023 24611 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 3.3 Cc1c(C(=O)OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2c1ccc1ccccc12 nan
3243891 24624 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 6 2.6 Cc1ccc(CNc2nc3ccccc3n3nnnc23)cc1 nan
CHEMBL1343134 24624 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 3 1 6 2.6 Cc1ccc(CNc2nc3ccccc3n3nnnc23)cc1 nan
2242090 24817 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 2 5 3.5 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 nan
CHEMBL1344848 24817 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 2 5 3.5 CS(=O)(=O)c1ccc2nc(NC(=O)Nc3ccccc3F)sc2c1 nan
665134 24853 7 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.7 O=C1CC(c2ccc(F)cc2)Cc2nc(NCc3ccco3)ncc21 nan
CHEMBL1345142 24853 7 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.7 O=C1CC(c2ccc(F)cc2)Cc2nc(NCc3ccco3)ncc21 nan
1096895 24902 48 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 2 5 0.6 O=C(O)c1nn2cc(CCO)cnc2c1Cl nan
CHEMBL1345601 24902 48 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 3 2 5 0.6 O=C(O)c1nn2cc(CCO)cnc2c1Cl nan
3640616 24973 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 6 3.4 O=C(OC1CCOC1=O)c1cc(-c2cccs2)nc2ccccc12 nan
CHEMBL1346240 24973 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 6 3.4 O=C(OC1CCOC1=O)c1cc(-c2cccs2)nc2ccccc12 nan
4846975 25145 22 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1-c1ccccc1 nan
CHEMBL1347553 25145 22 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1-c1ccccc1 nan
5219047 25191 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 5 2 4 2.1 CCC(C)NC(=O)COC(=O)c1ccc(Cl)cc1O nan
CHEMBL1347937 25191 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 285 5 2 4 2.1 CCC(C)NC(=O)COC(=O)c1ccc(Cl)cc1O nan
16193959 25227 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 11 2 9 2.0 NS(=O)(=O)c1ccc(CCNC(=O)CCCn2c(SCC(=O)N3CCCC3)nc3ccsc3c2=O)cc1 nan
CHEMBL1348274 25227 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 563 11 2 9 2.0 NS(=O)(=O)c1ccc(CCNC(=O)CCCn2c(SCC(=O)N3CCCC3)nc3ccsc3c2=O)cc1 nan
3342394 25472 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 1 5 3.3 C=CCN1C(=O)c2ccccc2Sc2ccc(C(=O)NCC(OC)OC)cc21 nan
CHEMBL1350401 25472 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 1 5 3.3 C=CCN1C(=O)c2ccccc2Sc2ccc(C(=O)NCC(OC)OC)cc21 nan
16011056 25974 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 6 4.1 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Br)c4)ncn32)s1 nan
CHEMBL1354311 25974 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 6 4.1 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Br)c4)ncn32)s1 nan
16025634 25983 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 4.1 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)cc1F nan
CHEMBL1354359 25983 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 1 6 4.1 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)cc1F nan
16009946 26017 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 1.6 CCc1cccc(CC)c1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1354862 26017 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 7 1.6 CCc1cccc(CC)c1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
16018892 26041 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 7 5.9 CCc1nnc(SCc2nc(-c3ccccc3F)oc2C)c2cc3sccc3n12 nan
CHEMBL1355121 26041 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 7 5.9 CCc1nnc(SCc2nc(-c3ccccc3F)oc2C)c2cc3sccc3n12 nan
4363763 26112 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 5 0 8 4.0 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1ccc(C(C)(C)C)cc1 nan
CHEMBL1356044 26112 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 5 0 8 4.0 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1ccc(C(C)(C)C)cc1 nan
16024946 26128 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 4 4.1 O=C(NCc1ccccc1Cl)c1ccc2c(c1)nnn2C1CCCC1 nan
CHEMBL1356218 26128 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 4 4.1 O=C(NCc1ccccc1Cl)c1ccc2c(c1)nnn2C1CCCC1 nan
15990261 26131 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 7 4.1 Cc1nnc2c(N3CCN(c4ccccc4)CC3)nc3ccc(C(=O)c4ccccc4)cc3n12 nan
CHEMBL1356236 26131 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 4 0 7 4.1 Cc1nnc2c(N3CCN(c4ccccc4)CC3)nc3ccc(C(=O)c4ccccc4)cc3n12 nan
16031511 26135 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(F)cc3)s2)cc1 nan
CHEMBL1356303 26135 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 6 4.1 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(F)cc3)s2)cc1 nan
16030397 26151 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 5 3.4 COCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
CHEMBL1356573 26151 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 1 5 3.4 COCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(C)cc1 nan
16009450 26168 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 3.5 O=C(COc1ccc(F)cc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1356791 26168 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 7 1 7 3.5 O=C(COc1ccc(F)cc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
756766 26180 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 1 4 3.8 Cn1c(SCc2cccc(F)c2)nc2c([nH]c3ccccc32)c1=O nan
CHEMBL1356946 26180 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 1 4 3.8 Cn1c(SCc2cccc(F)c2)nc2c([nH]c3ccccc32)c1=O nan
2141078 26192 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 6 4.7 COc1ccc(CNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1 nan
CHEMBL1357087 26192 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 6 4.7 COc1ccc(CNc2nc3c(-c4cccc(F)c4)nnn3c3ccccc23)cc1 nan
15988374 26223 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 6 0 6 5.7 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)c1ccc(Br)cc1 nan
CHEMBL1357521 26223 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 569 6 0 6 5.7 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)c1ccc(Br)cc1 nan
16020301 26237 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(F)cc3)c2=O)cc1 nan
CHEMBL1357758 26237 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3ccc(F)cc3)c2=O)cc1 nan
16024673 26247 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 3.9 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)c1 nan
CHEMBL1357949 26247 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 3.9 COc1cccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)c1 nan
16016274 26265 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 0 6 4.2 Cc1cccc(-c2noc(-c3ccc(N4CCCC4)c([N+](=O)[O-])c3)n2)c1 nan
CHEMBL1358183 26265 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 0 6 4.2 Cc1cccc(-c2noc(-c3ccc(N4CCCC4)c([N+](=O)[O-])c3)n2)c1 nan
20880782 26277 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 7 3.0 CC1CCCCN1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
CHEMBL1358259 26277 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 8 1 7 3.0 CC1CCCCN1CCNC(=O)CCc1nnc2n(Cc3ccccc3)c(=O)c3ccccc3n12 nan
15988865 26293 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 1 5 3.6 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1 nan
CHEMBL1358506 26293 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 1 5 3.6 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1 nan
16009824 26310 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 2 7 4.0 NS(=O)(=O)c1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccc(Cl)cc23)cc1 nan
CHEMBL1358725 26310 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 2 7 4.0 NS(=O)(=O)c1ccc(CCNc2nc3c(-c4cccc(F)c4)nnn3c3ccc(Cl)cc23)cc1 nan
1231059 26313 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.7 CC(=O)Nc1cccc(-c2nnc(-c3ccc(C)cc3)o2)c1 nan
CHEMBL1358793 26313 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.7 CC(=O)Nc1cccc(-c2nnc(-c3ccc(C)cc3)o2)c1 nan
1317893 26357 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.2 Cc1cc(OCC(=O)Nc2cc(-c3nc4ncccc4o3)ccc2C)ccc1Cl nan
CHEMBL1359048 26357 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.2 Cc1cc(OCC(=O)Nc2cc(-c3nc4ncccc4o3)ccc2C)ccc1Cl nan
3410425 26471 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 0 7 3.7 CCOCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OCC)ccc21 nan
CHEMBL1360046 26471 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 0 7 3.7 CCOCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OCC)ccc21 nan
2335932 26553 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(C)c1NC(=O)COC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1360771 26553 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(C)c1NC(=O)COC(=O)c1ccc2c(c1)OCO2 nan
16009752 26616 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 5 4.5 CCCCNc1nc2c(-c3cccc(C)c3)nnn2c2ccccc12 nan
CHEMBL1361402 26616 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 5 4.5 CCCCNc1nc2c(-c3cccc(C)c3)nnn2c2ccccc12 nan
16022921 26629 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
CHEMBL1361507 26629 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
2345644 26701 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.5 COc1cccc(C(=O)Nc2nnc(-c3ccc(OC)cc3OC)s2)c1 nan
CHEMBL1362103 26701 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.5 COc1cccc(C(=O)Nc2nnc(-c3ccc(OC)cc3OC)s2)c1 nan
16022913 26744 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 4.3 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1362452 26744 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 6 4.3 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
1313404 26758 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 7 4.0 CCOc1cc(C2C(C(=O)OC)=CN(C3CCCC3)C=C2C(=O)OC)cc(Br)c1O nan
CHEMBL1362550 26758 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 7 4.0 CCOc1cc(C2C(C(=O)OC)=CN(C3CCCC3)C=C2C(=O)OC)cc(Br)c1O nan
3448294 26779 24 None -19 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 0 3 5.0 O=Cc1cc2ccccc2nc1SCc1ccc(Cl)cc1 nan
CHEMBL1362687 26779 24 None -19 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 0 3 5.0 O=Cc1cc2ccccc2nc1SCc1ccc(Cl)cc1 nan
16026537 26904 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 6 4.2 CC(=O)c1cccc(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
CHEMBL1363862 26904 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 6 4.2 CC(=O)c1cccc(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
16009886 26914 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 7 4.3 COc1cccc(-n2c(=O)c3sc4ccccc4c3n(CC(=O)Nc3ccccc3C)c2=O)c1 nan
CHEMBL1363941 26914 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 5 1 7 4.3 COc1cccc(-n2c(=O)c3sc4ccccc4c3n(CC(=O)Nc3ccccc3C)c2=O)c1 nan
3359750 26982 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.2 O=C(CSc1nc(-c2ccccc2)c2ccccc2n1)Nc1ccc(F)cc1 nan
CHEMBL1364552 26982 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.2 O=C(CSc1nc(-c2ccccc2)c2ccccc2n1)Nc1ccc(F)cc1 nan
16019445 27037 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 8 5.7 Cc1ccc(C)c(Nc2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)c1 nan
CHEMBL1365021 27037 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 8 5.7 Cc1ccc(C)c(Nc2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)c1 nan
1152421 27236 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 6 5.4 CCOc1ccccc1NC(=O)CSc1nc(-c2cccs2)cc(C(F)(F)F)n1 nan
CHEMBL1366693 27236 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 6 5.4 CCOc1ccccc1NC(=O)CSc1nc(-c2cccs2)cc(C(F)(F)F)n1 nan
1080694 27264 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 5 3.2 CC1(C)CC(=O)c2sc(NS(=O)(=O)c3ccc(F)cc3)nc2C1 nan
CHEMBL1366962 27264 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 5 3.2 CC1(C)CC(=O)c2sc(NS(=O)(=O)c3ccc(F)cc3)nc2C1 nan
16022984 27338 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1367585 27338 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 COc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
16015654 27491 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 6 1 5 4.7 CC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
CHEMBL1368731 27491 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 6 1 5 4.7 CC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
2918354 27786 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 5 3.7 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1cccc(Br)c1 nan
CHEMBL1370753 27786 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 5 3.7 COCCCN1C(=O)C(O)=C(C(=O)c2ccco2)C1c1cccc(Br)c1 nan
1005238 27822 19 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 3.5 Cc1cc(NC(=O)CSc2nc3c(c(-c4cccnc4)c2C#N)CCC3)no1 nan
CHEMBL1371055 27822 19 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 7 3.5 Cc1cc(NC(=O)CSc2nc3c(c(-c4cccnc4)c2C#N)CCC3)no1 nan
1442423 28120 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 4.0 Cc1cc(NC(=O)CSc2nc(C(C)(C)C)nc3ccccc23)no1 nan
CHEMBL1373175 28120 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 6 4.0 Cc1cc(NC(=O)CSc2nc(C(C)(C)C)nc3ccccc23)no1 nan
6615570 28177 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 4 1 7 3.7 COc1ccc(C)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
CHEMBL1373530 28177 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 4 1 7 3.7 COc1ccc(C)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
2410746 28197 41 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 5 3.0 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
CHEMBL1373647 28197 41 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 5 3.0 CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3nc2Cl)cc1 nan
16009969 28324 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 7 1.3 CN(CC(=O)Nc1ccc(Cl)cc1F)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1374581 28324 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 7 1.3 CN(CC(=O)Nc1ccc(Cl)cc1F)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
9547710 28326 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 9 0.3 Cn1c(N)c(C(=O)COC(=O)c2ccnc3ccccc23)c(=O)n(C)c1=O nan
CHEMBL1374591 28326 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 9 0.3 Cn1c(N)c(C(=O)COC(=O)c2ccnc3ccccc23)c(=O)n(C)c1=O nan
4414022 28356 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 6 4.0 CCOC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc(C(C)=O)c1C nan
CHEMBL1374782 28356 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 6 4.0 CCOC(=O)c1c(NC(=O)C(C)Oc2ccccc2F)sc(C(C)=O)c1C nan
679950 28419 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.9 CCN(CC)c1ccc(-c2c(C#N)c(N)nc(OC)c2C#N)cc1 nan
CHEMBL1375207 28419 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 1 6 2.9 CCN(CC)c1ccc(-c2c(C#N)c(N)nc(OC)c2C#N)cc1 nan
5297522 28430 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 2 7 4.0 CCOC(=O)c1ccc(NC(=O)c2sc3nc4c(cc3c2N)N2CCC4CC2)cc1 nan
CHEMBL1375280 28430 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 4 2 7 4.0 CCOC(=O)c1ccc(NC(=O)c2sc3nc4c(cc3c2N)N2CCC4CC2)cc1 nan
16022988 28477 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 7 2.8 CCNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(OC)cc4)nc23)CC1 nan
CHEMBL1375625 28477 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 7 2.8 CCNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(OC)cc4)nc23)CC1 nan
1224964 28481 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 2 3 4.2 O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1cncc(Br)c1 nan
CHEMBL1375663 28481 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 2 3 4.2 O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1cncc(Br)c1 nan
16009514 28564 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1 nan
CHEMBL1376473 28564 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1 nan
16010769 28637 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 3.6 Cc1ccc(Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cccnc32)cc1 nan
CHEMBL1377217 28637 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 5 3.6 Cc1ccc(Cn2c(=O)n(Cc3ccccc3Cl)c(=O)c3cccnc32)cc1 nan
16024487 28691 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.2 Cc1cc(C)cc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)c1 nan
CHEMBL1377738 28691 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 1 5 4.2 Cc1cc(C)cc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)c1 nan
20887350 28984 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 7 1.3 Cc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2cc3ccccc3n12 nan
CHEMBL1380351 28984 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 7 1.3 Cc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2cc3ccccc3n12 nan
1943710 29143 8 None -6 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 5.1 CCCCc1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
CHEMBL1381564 29143 8 None -6 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 5.1 CCCCc1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
2220993 29180 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 4.5 Cc1cc(NC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)no1 nan
CHEMBL1381905 29180 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 1 5 4.5 Cc1cc(NC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)no1 nan
2551678 29188 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.3 Cc1[nH]c2ccccc2c1C(=O)CSc1nc2ccccc2c(=O)n1-c1ccccc1F nan
CHEMBL1381998 29188 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 5 1 5 5.3 Cc1[nH]c2ccccc2c1C(=O)CSc1nc2ccccc2c(=O)n1-c1ccccc1F nan
15997541 29458 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 2 7 3.4 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cccc(Cl)c3)c3ccccc3c2=O)cc1OC nan
CHEMBL1384419 29458 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 2 7 3.4 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cccc(Cl)c3)c3ccccc3c2=O)cc1OC nan
2412434 29531 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 nan
CHEMBL1385049 29531 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 2 6 2.0 NS(=O)(=O)c1ccc(NC(=O)CSc2ncnc3ccccc23)cc1 nan
1490540 29538 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 4 3.9 COc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
CHEMBL1385084 29538 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 4 3.9 COc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
1442725 29581 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 4 3.9 CC(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1385478 29581 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 4 3.9 CC(C)c1nc(SCC(=O)NC2CCCC2)c2ccccc2n1 nan
660521 29660 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCCCC2 nan
CHEMBL1386214 29660 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 6 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCCCC2 nan
658023 29986 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 2 7 2.7 CCOc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)c(OCC)c1 nan
CHEMBL1388744 29986 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 2 7 2.7 CCOc1ccc(C2C(C#N)=C(N)SC(N)=C2C#N)c(OCC)c1 nan
5913531 30039 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 8 1 8 3.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
CHEMBL1389094 30039 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 8 1 8 3.3 COc1cccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2CCCn2ccnc2)c1 nan
135749817 30184 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 2 4 4.9 N#C/C(=C(\O)c1cc(Cl)sc1Cl)c1nc2ccccc2[nH]1 nan
CHEMBL1390333 30184 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 2 4 4.9 N#C/C(=C(\O)c1cc(Cl)sc1Cl)c1nc2ccccc2[nH]1 nan
135468428 30362 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 5 2 7 5.1 Cc1cc(-n2c(SCC(=O)Nc3ccc(Br)cc3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1391897 30362 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 5 2 7 5.1 Cc1cc(-n2c(SCC(=O)Nc3ccc(Br)cc3)nc3nnc(C)c-3c2N)ccc1Cl nan
5393174 30388 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 4 3.2 COc1ccc(-c2cc3ccc(O)cc3oc2=O)cc1 nan
CHEMBL1392132 30388 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 1 4 3.2 COc1ccc(-c2cc3ccc(O)cc3oc2=O)cc1 nan
738837 30414 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 1 2 3.9 Cc1occc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
CHEMBL1392331 30414 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 2 1 2 3.9 Cc1occc1C(=O)Nc1cccc(C(F)(F)F)c1 nan
16194581 30482 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 9 0.9 CC(Sc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C)C(=O)O nan
CHEMBL1392938 30482 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 9 0.9 CC(Sc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C)C(=O)O nan
16029022 30707 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 2.5 COC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCC(C)CC3)cn2C)cc1 nan
CHEMBL1395073 30707 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 2.5 COC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCC(C)CC3)cn2C)cc1 nan
16024525 30755 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1395642 30755 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 5 4.2 Cc1ccc(C(=O)c2cn(CC(=O)NCc3ccccc3Cl)c3nc(C)ccc3c2=O)cc1 nan
16009355 30761 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 0 5 5.1 CC(C)c1ccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)cc1 nan
CHEMBL1395773 30761 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 0 5 5.1 CC(C)c1ccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)cc1 nan
16012262 30814 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1C nan
CHEMBL1396597 30814 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1C nan
16425494 30833 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
5522461 30833 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
CHEMBL1396834 30833 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.9 CN1CCN(Cc2c(O)ccc3cc(-c4ccccc4)c(=O)oc23)CC1 nan
15988387 30837 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 2 4 2.2 COc1cccc(C(=O)NC2=NC(c3ccccc3F)CC(=O)N2)c1 nan
CHEMBL1396902 30837 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 2 4 2.2 COc1cccc(C(=O)NC2=NC(c3ccccc3F)CC(=O)N2)c1 nan
16030463 30857 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 CC1CCN(C(=O)CSc2nc3ccccc3nc2Cc2ccccc2)CC1 nan
CHEMBL1397149 30857 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 CC1CCN(C(=O)CSc2nc3ccccc3nc2Cc2ccccc2)CC1 nan
16011758 30867 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.8 COc1ccc(OC)c(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1397253 30867 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 8 1 7 2.8 COc1ccc(OC)c(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
15988254 30925 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 0 7 3.1 COc1cc(OC)cc(-n2c(=O)c3ccccc3n(Cc3ccccc3C#N)c2=O)c1 nan
CHEMBL1398033 30925 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 0 7 3.1 COc1cc(OC)cc(-n2c(=O)c3ccccc3n(Cc3ccccc3C#N)c2=O)c1 nan
5089883 30934 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 6 5.9 O=C(CSc1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccccc1)c1ccc(Cl)cc1 nan
CHEMBL1398184 30934 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 6 5.9 O=C(CSc1oc(-c2ccc(F)cc2)nc1S(=O)(=O)c1ccccc1)c1ccc(Cl)cc1 nan
16020303 30939 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3cccc(F)c3)c2=O)cc1 nan
CHEMBL1398259 30939 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 2 7 4.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(CC(=O)Nc3cccc(F)c3)c2=O)cc1 nan
16025636 30945 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 4 1 6 3.9 CN1c2cc(Cl)ccc2-c2nc(SCC(=O)Nc3ccc(F)cc3F)ncc2S1(=O)=O nan
CHEMBL1398402 30945 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 4 1 6 3.9 CN1c2cc(Cl)ccc2-c2nc(SCC(=O)Nc3ccc(F)cc3F)ncc2S1(=O)=O nan
16030333 30954 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 6 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2OC)cc1 nan
CHEMBL1398464 30954 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 6 4.6 COc1ccc(CNC(=O)CSc2nc3ccccc3nc2Cc2ccccc2OC)cc1 nan
16022444 30980 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 7 4.8 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3nc2s1 nan
CHEMBL1398653 30980 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 7 4.8 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3nc2s1 nan
4135187 31033 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 6 4.4 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2F)cc1 nan
CHEMBL1399236 31033 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 6 4.4 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2Cc2ccccc2F)cc1 nan
2135591 31037 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.7 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(Cl)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1399275 31037 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 7 1 7 4.7 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(Cl)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
135546815 31044 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 5 4.0 Cc1ccc(NC(=O)C(C)Sc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c(C)c1 nan
CHEMBL1399310 31044 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 2 5 4.0 Cc1ccc(NC(=O)C(C)Sc2nc(-c3ccccc3)c(C#N)c(=O)[nH]2)c(C)c1 nan
135513990 31091 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 5 4.4 Cc1c(Br)ccc(NC(=O)CSc2nc(O)c3ccccc3n2)c1C nan
CHEMBL1399762 31091 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 5 4.4 Cc1c(Br)ccc(NC(=O)CSc2nc(O)c3ccccc3n2)c1C nan
6484563 31166 36 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 0 2 2 3.4 SC1=NC2(CCCCC2)Nc2ccccc21 nan
CHEMBL1400466 31166 36 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 232 0 2 2 3.4 SC1=NC2(CCCCC2)Nc2ccccc21 nan
16011170 31188 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.6 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(Cl)cc1F nan
CHEMBL1400646 31188 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.6 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(Cl)cc1F nan
2404851 31214 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 1 7 1.0 O=S(=O)(c1cccc(-c2nnc(S)o2)c1)N1CCOCC1 nan
CHEMBL1400922 31214 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 3 1 7 1.0 O=S(=O)(c1cccc(-c2nnc(S)o2)c1)N1CCOCC1 nan
659778 31239 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1F nan
CHEMBL1401137 31239 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1F nan
4852309 31254 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 3 4.5 COc1cc(C(=O)NC(c2ccccc2)c2ccccc2)cc(OC)c1C nan
CHEMBL1401266 31254 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 3 4.5 COc1cc(C(=O)NC(c2ccccc2)c2ccccc2)cc(OC)c1C nan
1994854 31257 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 8 3.6 CCn1c(SCC(=O)Nc2ccc(C(C)=O)cc2)nc2nc3c(cc2c1=O)COC(C)(C)C3 nan
CHEMBL1401292 31257 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 8 3.6 CCn1c(SCC(=O)Nc2ccc(C(C)=O)cc2)nc2nc3c(cc2c1=O)COC(C)(C)C3 nan
16011439 31557 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 6 6.3 COc1ccc(Cn2c(SCc3ccc(C(=O)NC(C)c4ccccc4)cc3)nc3cccnc32)cc1 nan
CHEMBL1404015 31557 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 6 6.3 COc1ccc(Cn2c(SCc3ccc(C(=O)NC(C)c4ccccc4)cc3)nc3cccnc32)cc1 nan
2456084 31562 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 2 8 4.0 COc1cc(NC(=O)c2ccco2)c(C(=O)OCC(=O)Nc2ncc(Cl)cc2Cl)cc1OC nan
CHEMBL1404053 31562 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 2 8 4.0 COc1cc(NC(=O)c2ccco2)c(C(=O)OCC(=O)Nc2ncc(Cl)cc2Cl)cc1OC nan
2826390 31654 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 5 2.9 COC(=O)c1sccc1NC(=O)C1CC(C)=C(C)CC1C(=O)O nan
CHEMBL1404933 31654 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 2 5 2.9 COC(=O)c1sccc1NC(=O)C1CC(C)=C(C)CC1C(=O)O nan
16007508 31666 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 3 5.7 CCc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1405105 31666 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 3 5.7 CCc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
1930124 31757 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccccc2)c(S(=O)(=O)c2ccc(C)cc2)c2nc3ccccc3nc21 nan
CHEMBL1405964 31757 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccccc2)c(S(=O)(=O)c2ccc(C)cc2)c2nc3ccccc3nc21 nan
135464462 31912 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 6 3.1 CN(C)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
CHEMBL1407344 31912 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 3 1 6 3.1 CN(C)Cc1c(O)ccc2cc(-c3nc4ccccc4n3C)c(=O)oc12 nan
3221573 31943 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 8 3 5 3.0 COCCCN=C(S)NCCNc1nc2c(C)c(C)ccc2cc1C#N nan
CHEMBL1407546 31943 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 8 3 5 3.0 COCCCN=C(S)NCCNc1nc2c(C)c(C)ccc2cc1C#N nan
266900 31957 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 3 4.3 COC(=O)c1cc(C)nc2c(C)cc3[nH]c4ccccc4c3c12 nan
CHEMBL1407610 31957 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 3 4.3 COC(=O)c1cc(C)nc2c(C)cc3[nH]c4ccccc4c3c12 nan
16018228 32020 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 5 1.1 CN(C)CCNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
CHEMBL1408060 32020 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 5 1.1 CN(C)CCNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 nan
800213 32052 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 4.8 CC(C)(C)c1ccc(-c2nnc(NC(=O)c3ccccc3)s2)cc1 nan
CHEMBL1408281 32052 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 4 4.8 CC(C)(C)c1ccc(-c2nnc(NC(=O)c3ccccc3)s2)cc1 nan
4837904 32116 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.1 COc1ccc(CCNC(=O)Cc2c(C)c3cc4c(C)coc4cc3oc2=O)cc1OC nan
CHEMBL1408806 32116 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 6 4.1 COc1ccc(CCNC(=O)Cc2c(C)c3cc4c(C)coc4cc3oc2=O)cc1OC nan
915456 32119 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 4 4.6 Oc1ccccc1-c1nc(NCc2ccccc2)c2ccccc2n1 nan
CHEMBL1408828 32119 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 4 4.6 Oc1ccccc1-c1nc(NCc2ccccc2)c2ccccc2n1 nan
15988127 32249 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 6 3 6 7.6 COc1ccccc1NC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(C)cc3C)c(-c3ccccc3Cl)c2c1N nan
CHEMBL1409862 32249 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 6 3 6 7.6 COc1ccccc1NC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(C)cc3C)c(-c3ccccc3Cl)c2c1N nan
649505 32252 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 2.3 O=C(Nc1ccc2c(c1)OCO2)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1 nan
CHEMBL1409886 32252 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 2.3 O=C(Nc1ccc2c(c1)OCO2)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2)CC1 nan
688670 32270 29 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 4 3.5 COc1ccc(-c2cc(=O)c3cc(OC)ccc3o2)cc1 nan
CHEMBL1410006 32270 29 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 3 0 4 3.5 COc1ccc(-c2cc(=O)c3cc(OC)ccc3o2)cc1 nan
4137223 32378 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 5 5.2 Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C)c(F)c3)sc2n1 nan
CHEMBL1410912 32378 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 5 5.2 Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C)c(F)c3)sc2n1 nan
1088392 32569 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 7 3.0 COC(=O)c1sc(NC(=O)c2c(OC)cccc2OC)c(C#N)c1C nan
CHEMBL1412474 32569 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 7 3.0 COC(=O)c1sc(NC(=O)c2c(OC)cccc2OC)c(C#N)c1C nan
790792 32730 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 3 3.4 CCc1c(C)nc2ccc(OC)cc2c1S nan
CHEMBL1413735 32730 42 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 233 2 1 3 3.4 CCc1c(C)nc2ccc(OC)cc2c1S nan
16015840 32763 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 4 5.0 Cc1cccc(-c2nc3cc(NC(=O)COc4ccccc4F)ccc3o2)c1 nan
CHEMBL1413987 32763 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 4 5.0 Cc1cccc(-c2nc3cc(NC(=O)COc4ccccc4F)ccc3o2)c1 nan
655034 32859 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 2 7 2.4 COc1cc(CC(NC(C)=O)C(=O)NC2CCN(c3nc(C)cc(C)c3C#N)CC2)cc(OC)c1 nan
CHEMBL1414774 32859 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 2 7 2.4 COc1cc(CC(NC(C)=O)C(=O)NC2CCN(c3nc(C)cc(C)c3C#N)CC2)cc(OC)c1 nan
16016268 32861 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 0 8 5.0 COc1ccccc1N1CCN(c2ccc(-c3nc(-c4ccccc4C)no3)cc2[N+](=O)[O-])CC1 nan
CHEMBL1414801 32861 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 0 8 5.0 COc1ccccc1N1CCN(c2ccc(-c3nc(-c4ccccc4C)no3)cc2[N+](=O)[O-])CC1 nan
2156145 32958 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 9 4.3 COc1ccc(-n2c(SCC(=O)Nc3cc(C)on3)nc3c4ccccc4nc-3c2O)cc1 nan
CHEMBL1415709 32958 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 9 4.3 COc1ccc(-n2c(SCC(=O)Nc3cc(C)on3)nc3c4ccccc4nc-3c2O)cc1 nan
7190669 33019 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1 nan
CHEMBL1416264 33019 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 7 3.1 O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)Nc1ccc(F)cc1 nan
16012962 33034 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 0 6 3.9 Fc1cccc(-n2ncc3c2ncn2nc(-c4ccccc4Cl)nc32)c1 nan
CHEMBL1416375 33034 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 0 6 3.9 Fc1cccc(-n2ncc3c2ncn2nc(-c4ccccc4Cl)nc32)c1 nan
4808145 33191 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 7 1.3 Cn1c(=O)c2c(ncn2CCOc2ccc(Br)cc2)n(C)c1=O nan
CHEMBL1417778 33191 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 0 7 1.3 Cn1c(=O)c2c(ncn2CCOc2ccc(Br)cc2)n(C)c1=O nan
16009664 33270 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
CHEMBL1418446 33270 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 4.6 COc1ccc(CNc2nc3c(-c4ccccc4)nnn3c3ccccc23)cc1 nan
4625060 33341 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 4 2.2 O=C(CC1N=C2c3ccccc3NC(=S)N2C1=O)NC1CCCCC1 nan
CHEMBL1419028 33341 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 4 2.2 O=C(CC1N=C2c3ccccc3NC(=S)N2C1=O)NC1CCCCC1 nan
665236 33387 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 4.4 CCc1nc(SCC(=O)Nc2ccc3c(c2)OCCO3)c2oc3ccccc3c2n1 nan
CHEMBL1419387 33387 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 7 4.4 CCc1nc(SCC(=O)Nc2ccc3c(c2)OCCO3)c2oc3ccccc3c2n1 nan
20927027 33404 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 2.0 O=S(=O)(c1ccc(-c2ccc(O)nn2)o1)N1CCN(c2ccccc2)CC1 nan
CHEMBL1419593 33404 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 2.0 O=S(=O)(c1ccc(-c2ccc(O)nn2)o1)N1CCN(c2ccccc2)CC1 nan
16024782 33563 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4F)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1420848 33563 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 4 0 5 3.9 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4F)CC3)ccc2c1)N1CCCCC1 nan
3185701 33587 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 541 10 3 8 3.0 CCOc1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2F)cc1 nan
CHEMBL1421091 33587 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 541 10 3 8 3.0 CCOc1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2F)cc1 nan
1078539 33840 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 7 2.5 Cc1cccc(-n2ncc3c(N4CCC5(CC4)OCCO5)ncnc32)c1 nan
CHEMBL1423202 33840 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 7 2.5 Cc1cccc(-n2ncc3c(N4CCC5(CC4)OCCO5)ncnc32)c1 nan
993322 33879 15 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 4.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)Nc3cc(C)on3)n2)cc1 nan
CHEMBL1423477 33879 15 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 7 4.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)Nc3cc(C)on3)n2)cc1 nan
16194711 34089 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 9 1.5 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(CCNC(=O)c4ccccc4)n3n2)CC1 nan
CHEMBL1425185 34089 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 9 1.5 CCOC(=O)N1CCN(C(=O)CSc2ccc3nnc(CCNC(=O)c4ccccc4)n3n2)CC1 nan
661193 34273 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 5 1 7 1.9 Cc1cccc(-n2ncc3c(NCCN4CCOCC4)ncnc32)c1 nan
CHEMBL1426726 34273 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 5 1 7 1.9 Cc1cccc(-n2ncc3c(NCCN4CCOCC4)ncnc32)c1 nan
2999700 34418 3 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 5 4.6 Cn1c(/C(C#N)=C(\O)COc2ccc3ccccc3c2)nc2ccccc21 nan
CHEMBL1428087 34418 3 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 1 5 4.6 Cn1c(/C(C#N)=C(\O)COc2ccc3ccccc3c2)nc2ccccc21 nan
1371384 34541 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 1 4 2.7 Cc1ccc(/C=C2/SC(=O)NC2=S)o1 nan
CHEMBL1429158 34541 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 225 1 1 4 2.7 Cc1ccc(/C=C2/SC(=O)NC2=S)o1 nan
2815019 34838 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 8 0.7 Cn1c(=O)c2c(nc(Sc3ccccc3N)n2C)n(C)c1=O nan
CHEMBL1431497 34838 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 8 0.7 Cn1c(=O)c2c(nc(Sc3ccccc3N)n2C)n(C)c1=O nan
2114663 34881 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 5 5.3 Cc1onc(-c2ccccc2)c1C(=O)Nc1nc(-c2cc(F)ccc2F)cs1 nan
CHEMBL1431887 34881 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 5 5.3 Cc1onc(-c2ccccc2)c1C(=O)Nc1nc(-c2cc(F)ccc2F)cs1 nan
650995 34984 14 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 6 4.2 Cc1nonc1NC(=O)CSc1nc2cc(Cl)ccc2c2c1CCCC2 nan
CHEMBL1432773 34984 14 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 6 4.2 Cc1nonc1NC(=O)CSc1nc2cc(Cl)ccc2c2c1CCCC2 nan
15989049 35074 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 529 8 1 8 3.9 O=C(CCCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1433448 35074 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 529 8 1 8 3.9 O=C(CCCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
16009658 35088 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1cccc(F)c1 nan
CHEMBL1433649 35088 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.6 O=C(Nc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)cc1)c1cccc(F)c1 nan
16030989 35094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 4.3 COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1433722 35094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 4.3 COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
15990910 35107 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 4 5.8 CSc1cccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
CHEMBL1433922 35107 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 4 5.8 CSc1cccc(Nc2cc(C(=O)NC3CCCCC3)c3ccccc3n2)c1 nan
16008787 35148 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.3 COc1ccccc1CNC(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1 nan
CHEMBL1434647 35148 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.3 COc1ccccc1CNC(=O)c1cc2c(=O)oc3ccc(C)cc3c2s1 nan
16022785 35149 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)c(C)c1 nan
CHEMBL1434648 35149 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)c(C)c1 nan
24819144 35154 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 6 6.0 COC(=O)c1ccc(/C=C/c2c(-c3ccsc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
CHEMBL1434681 35154 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 6 6.0 COC(=O)c1ccc(/C=C/c2c(-c3ccsc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
135546816 35160 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 2 6 3.8 CCOc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1 nan
CHEMBL1434743 35160 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 2 6 3.8 CCOc1ccccc1NC(=O)C(C)Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1 nan
16024519 35178 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 7 3.7 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1435013 35178 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 7 3.7 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3nc(C)ccc3c2=O)cc1 nan
16018510 35182 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 5.3 COc1cccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)c1 nan
CHEMBL1435044 35182 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 5.3 COc1cccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)c1 nan
15988487 35192 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 4 4.3 CC1(C)CC(=O)c2cc(-c3nc(-c4ccccc4)cs3)c(=O)[nH]c2C1 nan
CHEMBL1435109 35192 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 4 4.3 CC1(C)CC(=O)c2cc(-c3nc(-c4ccccc4)cs3)c(=O)[nH]c2C1 nan
6225711 35257 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 4 3.6 Cc1cc(O)c2c(C)c(CC(=O)NCc3ccccc3Cl)c(=O)oc2c1 nan
CHEMBL1435970 35257 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 2 4 3.6 Cc1cc(O)c2c(C)c(CC(=O)NCc3ccccc3Cl)c(=O)oc2c1 nan
15987771 35261 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 0 5 3.5 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)c21 nan
CHEMBL1436008 35261 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 5 0 5 3.5 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)c21 nan
5059361 35280 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 6 4.7 Cc1cccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)c1 nan
CHEMBL1436184 35280 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 0 6 4.7 Cc1cccc(-c2nc3ccccc3n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c23)c1 nan
4230972 35352 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 9 2 7 4.8 CC(C)c1ccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccco4)C(=O)N23)cc1 nan
CHEMBL1437178 35352 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 9 2 7 4.8 CC(C)c1ccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccco4)C(=O)N23)cc1 nan
16007712 35353 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.5 CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCN(c3cc(Cl)ccc3C)CC1)cn2C nan
CHEMBL1437207 35353 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 0 6 3.5 CCN(CC)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)N1CCN(c3cc(Cl)ccc3C)CC1)cn2C nan
15988469 35434 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 4.8 COc1ccc(NC(=O)C2CCN(c3ccc(Sc4ccc(C)cc4)nn3)CC2)cc1 nan
CHEMBL1438027 35434 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 6 1 6 4.8 COc1ccc(NC(=O)C2CCN(c3ccc(Sc4ccc(C)cc4)nn3)CC2)cc1 nan
3230795 35448 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 0 6 4.6 CN(C(=O)CSC1=NC2C(N=N1)c1cc(Br)ccc1N2C)C1CCCCC1 nan
CHEMBL1438136 35448 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 3 0 6 4.6 CN(C(=O)CSC1=NC2C(N=N1)c1cc(Br)ccc1N2C)C1CCCCC1 nan
16017737 35659 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 1.9 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccc(F)cc1 nan
CHEMBL1440044 35659 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 1.9 O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)Nc1ccc(F)cc1 nan
16024943 35704 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 4.0 CC(=O)c1ccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)cc1 nan
CHEMBL1440442 35704 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 4.0 CC(=O)c1ccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)cc1 nan
16195917 35777 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 8 0.2 Cn1c(N)c(C(=O)COC(=O)CC2CC3CCC2C3)c(=O)n(C)c1=O nan
CHEMBL1441131 35777 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 8 0.2 Cn1c(N)c(C(=O)COC(=O)CC2CC3CCC2C3)c(=O)n(C)c1=O nan
16009208 35873 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 3.2 CCOc1ccc(CNC(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c32)cc1 nan
CHEMBL1441997 35873 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 3.2 CCOc1ccc(CNC(=O)Cn2ncc3c(=O)oc4ccc(C)cc4c32)cc1 nan
2980137 36085 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 7 2.7 COc1ccc(-n2c(SC(C)C(=O)N3CCOCC3)nc3ccccc3c2=O)cc1 nan
CHEMBL1443960 36085 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 7 2.7 COc1ccc(-n2c(SC(C)C(=O)N3CCOCC3)nc3ccccc3c2=O)cc1 nan
2421482 36152 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 9 3.0 CCOC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
CHEMBL1444560 36152 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 9 3.0 CCOC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 nan
2136705 36197 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 7 3.8 COc1cc2c(=O)c(S(=O)(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2cc1OC nan
CHEMBL1444994 36197 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 7 3.8 COc1cc2c(=O)c(S(=O)(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2cc1OC nan
4154281 36219 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 5 5.3 O=C(CSc1ncnc2c1sc1ccccc12)Nc1ccc(Br)cc1 nan
CHEMBL1445182 36219 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 5 5.3 O=C(CSc1ncnc2c1sc1ccccc12)Nc1ccc(Br)cc1 nan
738863 36246 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 3.6 O=C(Nc1nc(=O)c2ccccc2s1)c1ccc(Cl)cc1 nan
CHEMBL1445436 36246 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 3.6 O=C(Nc1nc(=O)c2ccccc2s1)c1ccc(Cl)cc1 nan
3151463 36607 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 7 1.8 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1448581 36607 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 7 1.8 COCCCn1c(=N)c(C(=O)NC2CCCC2)cc2c(=O)n3ccccc3nc21 nan
20903711 36679 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 7 1.1 COCCNC(=O)CCc1nnc2ccc(N3CCC(C)CC3)nn12 nan
CHEMBL1449064 36679 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 7 1 7 1.1 COCCNC(=O)CCc1nnc2ccc(N3CCC(C)CC3)nn12 nan
9550466 36691 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.5 Cc1ccc(-n2nc(C)c3c(C)c(CCC(=O)NC(C)c4ccccc4)c(C)nc32)cc1 nan
CHEMBL1449158 36691 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.5 Cc1ccc(-n2nc(C)c3c(C)c(CCC(=O)NC(C)c4ccccc4)c(C)nc32)cc1 nan
1440341 36697 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 3 4.8 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1ccccc1)CCC3 nan
CHEMBL1449215 36697 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 3 4.8 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1ccccc1)CCC3 nan
1034641 36815 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 5 3.8 Cc1ccc(-n2c(N)c(C#N)c(-c3ccc(Cl)cc3)c(C#N)c2=O)cc1 nan
CHEMBL1450150 36815 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 1 5 3.8 Cc1ccc(-n2c(N)c(C#N)c(-c3ccc(Cl)cc3)c(C#N)c2=O)cc1 nan
16009195 36835 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 3.5 CCN(Cc1ccccc1)C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c21 nan
CHEMBL1450283 36835 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 3.5 CCN(Cc1ccccc1)C(=O)Cn1ncc2c(=O)oc3ccc(C)cc3c21 nan
1341628 36897 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 4 5.8 CC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccc(Br)cc2)cc1 nan
CHEMBL1450882 36897 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 4 5.8 CC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccc(Br)cc2)cc1 nan
16019140 37310 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 8 3.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(Cc3ccc4c(c3)OCO4)c(=O)c3oc4ccccc4c32)c1 nan
CHEMBL1454100 37310 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 8 3.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(Cc3ccc4c(c3)OCO4)c(=O)c3oc4ccccc4c32)c1 nan
16009221 37354 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 4.6 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1454484 37354 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 4.6 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
16026522 37382 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 5 4.3 CCOC(=O)c1sc2cccc(F)c2c1S(=O)(=O)NCc1ccccc1Cl nan
CHEMBL1454707 37382 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 5 4.3 CCOC(=O)c1sc2cccc(F)c2c1S(=O)(=O)NCc1ccccc1Cl nan
6011252 37425 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 12 1 8 4.5 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCN2CCOCC2)cc1OC nan
CHEMBL1455062 37425 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 12 1 8 4.5 CCCCOc1ccc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2CCCN2CCOCC2)cc1OC nan
16026066 37441 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.7 CCc1ccccc1NC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
CHEMBL1455235 37441 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.7 CCc1ccccc1NC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
24819160 37550 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 6 5.9 COC(=O)c1ccc(/C=C/c2c(-c3ccc(OC)cc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
CHEMBL1456226 37550 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 0 6 5.9 COC(=O)c1ccc(/C=C/c2c(-c3ccc(OC)cc3)oc3ccc(N4CCOCC4)cc23)cc1 nan
135520065 37745 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 2.5 COC(=O)C(CC(C)C)NC(=O)CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
CHEMBL1457936 37745 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 2.5 COC(=O)C(CC(C)C)NC(=O)CSc1nc(O)c(C#N)c(-c2ccccc2)n1 nan
2125831 37792 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 2 2 3.9 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)cc2F)c1C nan
CHEMBL1458351 37792 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 2 2 3.9 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)cc2F)c1C nan
1110886 38062 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 3 5 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccc(NC(C)=O)cc3)nc(-c3ccc(NC(C)=O)cc3)n2)cc1 nan
CHEMBL1460618 38062 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 3 5 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccc(NC(C)=O)cc3)nc(-c3ccc(NC(C)=O)cc3)n2)cc1 nan
17255621 38118 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 6 3.7 CCOc1ccc(NC(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
CHEMBL1461095 38118 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 2 6 3.7 CCOc1ccc(NC(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
4437250 38121 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 2 2 4.2 CCN=C(S)N(CCc1c(C)[nH]c2ccccc12)Cc1cccnc1 nan
CHEMBL1461107 38121 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 2 2 4.2 CCN=C(S)N(CCc1c(C)[nH]c2ccccc12)Cc1cccnc1 nan
2784799 38247 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 1 1 4 2.5 O=C1C([N+](=O)[O-])=C(O)c2cccc3cccc1c23 nan
CHEMBL1462267 38247 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 1 1 4 2.5 O=C1C([N+](=O)[O-])=C(O)c2cccc3cccc1c23 nan
1442463 38414 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 5 4.0 CC(C)(C)c1nc(SCC(=O)N2CC(=O)Nc3ccccc32)c2ccccc2n1 nan
CHEMBL1463696 38414 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 5 4.0 CC(C)(C)c1nc(SCC(=O)N2CC(=O)Nc3ccccc32)c2ccccc2n1 nan
664194 38442 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 0 7 2.7 c1ccc(-n2ncc3c2ncn2nc(-c4ccco4)nc32)cc1 nan
CHEMBL1463869 38442 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 2 0 7 2.7 c1ccc(-n2ncc3c2ncn2nc(-c4ccco4)nc32)cc1 nan
2370579 38507 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 8 -0.4 Cn1c(N)c(C(=O)COC(=O)C2CCCC2)c(=O)n(C)c1=O nan
CHEMBL1464368 38507 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 8 -0.4 Cn1c(N)c(C(=O)COC(=O)C2CCCC2)c(=O)n(C)c1=O nan
4230513 38549 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 9 0.6 CC(C)Cn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1464655 38549 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 9 0.6 CC(C)Cn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
1214727 38685 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 5 4.2 Cc1c(-c2ccc(Cl)cc2)oc(=O)c2c(N)n(-c3ccccc3)nc12 nan
CHEMBL1465659 38685 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 5 4.2 Cc1c(-c2ccc(Cl)cc2)oc(=O)c2c(N)n(-c3ccccc3)nc12 nan
4225516 38790 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 O=C(O)c1cccnc1SCc1cn2cc(Br)ccc2n1 nan
CHEMBL1466534 38790 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 5 3.5 O=C(O)c1cccnc1SCc1cn2cc(Br)ccc2n1 nan
16020097 38901 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 9 1 7 3.3 CCCCN(C)CCNC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1467366 38901 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 9 1 7 3.3 CCCCN(C)CCNC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c1c1ccccc1n2C nan
3137696 38917 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 0 7 -0.2 COCCn1c(Br)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1467508 38917 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 0 7 -0.2 COCCn1c(Br)nc2c1c(=O)n(C)c(=O)n2C nan
2396532 39016 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 2 9 -0.1 CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
CHEMBL1468416 39016 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 2 9 -0.1 CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1C nan
4994172 39142 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 2 5 4.0 Nc1cc(C(=O)Nc2ccc(Cl)cc2)ccc1N1CC2CC(C1)c1cccc(=O)n1C2 nan
CHEMBL1469442 39142 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 2 5 4.0 Nc1cc(C(=O)Nc2ccc(Cl)cc2)ccc1N1CC2CC(C1)c1cccc(=O)n1C2 nan
2517516 39294 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 2.7 CC(C)COc1ccc(C(=O)N2C(=O)c3ccc(N)cc3C2=O)cc1 nan
CHEMBL1470757 39294 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 2.7 CC(C)COc1ccc(C(=O)N2C(=O)c3ccc(N)cc3C2=O)cc1 nan
4968659 39423 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 9 2 6 6.1 CCc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
CHEMBL1471857 39423 6 None -5 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 9 2 6 6.1 CCc1ccc(-c2nc(NC(=O)c3ccc(OCC(=O)Nc4ccc(F)cc4)c(OC)c3)sc2C)cc1 nan
16032187 39533 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 8 2.7 Cc1cc(NC(=O)CSc2ncc(C(=O)Nc3ccc(Cl)cc3)c(=O)n2C)no1 nan
CHEMBL1472946 39533 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 8 2.7 Cc1cc(NC(=O)CSc2ncc(C(=O)Nc3ccc(Cl)cc3)c(=O)n2C)no1 nan
16416626 39576 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
7205030 39576 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
CHEMBL1473511 39576 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 2 6 2.3 O=c1oc2c(CN3CCN(CCO)CC3)c(O)ccc2cc1-c1ccccc1 nan
16022561 39578 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
CHEMBL1473551 39578 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
16025981 39614 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 5 4.3 O=c1cc2nc(-c3ccccc3F)nc(SCc3ccc(Br)cc3)n2[nH]1 nan
CHEMBL1474099 39614 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 5 4.3 O=c1cc2nc(-c3ccccc3F)nc(SCc3ccc(Br)cc3)n2[nH]1 nan
5302625 39645 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 2 5 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
CHEMBL1474507 39645 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 2 5 6.0 CCc1ccc(NC(=O)c2sc3nc(C)cc(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
20893081 39683 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 8 2.1 COc1ccc(NC(=O)C2CCCN2c2nn3c(=O)cc(C)nc3s2)cc1 nan
CHEMBL1475089 39683 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 8 2.1 COc1ccc(NC(=O)C2CCCN2c2nn3c(=O)cc(C)nc3s2)cc1 nan
15988958 39701 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(CNC(=O)CCCCCn2c(=O)c3sccc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
CHEMBL1475354 39701 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(CNC(=O)CCCCCn2c(=O)c3sccc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
16020297 39722 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 557 7 1 6 5.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3ccc(F)cc3Cl)c2=O)cc1 nan
CHEMBL1475582 39722 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 557 7 1 6 5.2 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3ccc(F)cc3Cl)c2=O)cc1 nan
16015655 39775 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.6 COc1ccccc1C(=O)Nc1ccc2nc(SCC(=O)N3CCCc4ccccc43)sc2c1 nan
CHEMBL1476387 39775 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 6 5.6 COc1ccccc1C(=O)Nc1ccc2nc(SCC(=O)N3CCCc4ccccc43)sc2c1 nan
15988828 39808 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 4.0 O=C(Nc1cccc(Cl)c1)c1cc(-c2ccc3c(c2)OCO3)on1 nan
CHEMBL1476787 39808 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 4.0 O=C(Nc1cccc(Cl)c1)c1cc(-c2ccc3c(c2)OCO3)on1 nan
15988909 39849 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 0 7 3.4 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)c1 nan
CHEMBL1477251 39849 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 0 7 3.4 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)c1 nan
16027484 39865 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1cccc(F)c1 nan
CHEMBL1477385 39865 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1)c1cccc(F)c1 nan
16009837 39873 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 7 4.7 COc1cccc(NC(=O)Cn2c(=O)n(-c3ccc(Cl)cc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1477435 39873 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 1 7 4.7 COc1cccc(NC(=O)Cn2c(=O)n(-c3ccc(Cl)cc3)c(=O)c3sc4ccccc4c32)c1 nan
663717 39928 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 7 4.0 CCOCCCn1cnc2c(c1=O)c1nc3ccccc3nc1n2-c1ccc(C)cc1 nan
CHEMBL1477914 39928 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 7 4.0 CCOCCCn1cnc2c(c1=O)c1nc3ccccc3nc1n2-c1ccc(C)cc1 nan
16018985 39943 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1478117 39943 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 5 4.3 O=C(NCCc1ccc(Cl)cc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
15988423 40023 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 4 2.8 COc1ccccc1NC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O nan
CHEMBL1478841 40023 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 2 4 2.8 COc1ccccc1NC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O nan
24819115 40074 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 5 6 2.9 Nc1c(Cl)cc(-c2nc3cc(C(=O)NCCO)ccc3c(O)c2O)cc1Cl nan
CHEMBL1479302 40074 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 5 6 2.9 Nc1c(Cl)cc(-c2nc3cc(C(=O)NCCO)ccc3c(O)c2O)cc1Cl nan
2511800 40098 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 2 5 4.0 CCOc1ncccc1C(=O)Nc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 nan
CHEMBL1479469 40098 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 2 5 4.0 CCOc1ncccc1C(=O)Nc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 nan
3352626 40241 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 11 1 6 5.3 CCCC[S+]([O-])CC(O)CSc1nc(-c2ccc(OC)cc2)cc(-c2ccccc2)c1C#N nan
CHEMBL1480619 40241 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 11 1 6 5.3 CCCC[S+]([O-])CC(O)CSc1nc(-c2ccc(OC)cc2)cc(-c2ccccc2)c1C#N nan
20957489 40387 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)n2n1 nan
CHEMBL1481894 40387 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 9 1 8 2.0 O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccc(F)cc4)CC3)n2n1 nan
16033868 40392 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 2 9 4.0 COc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
CHEMBL1481939 40392 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 2 9 4.0 COc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
5297519 40442 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(C(F)(F)F)cc1)C1CCN2CC1 nan
CHEMBL1482409 40442 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(C(F)(F)F)cc1)C1CCN2CC1 nan
16030774 40504 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 1.2 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1482929 40504 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 6 1 9 1.2 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3ccccc3F)nc2n(C)c1=O nan
16017755 40583 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 5 2.0 O=C(Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O)NCCc1ccccc1 nan
CHEMBL1483603 40583 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 5 2.0 O=C(Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O)NCCc1ccccc1 nan
16015423 40597 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 nan
CHEMBL1483703 40597 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccccc3F)cc2s1 nan
1477383 40877 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 3 3 2.7 O=C(NC(=S)Nc1cccc2[nH]ncc12)c1ccccc1 nan
CHEMBL1486203 40877 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 3 3 2.7 O=C(NC(=S)Nc1cccc2[nH]ncc12)c1ccccc1 nan
16009820 40910 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 4.5 CC(C)Nc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1486479 40910 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 4.5 CC(C)Nc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
646986 40995 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 5 3.5 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccnc1)c1ccco1 nan
CHEMBL1487207 40995 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 1 5 3.5 O=C(C1=C(O)C(=O)N(CCc2ccccc2)C1c1cccnc1)c1ccco1 nan
15996976 41094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 2 4 3.0 CC1CCN(S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccc(F)cc4)c(=O)c3c2)CC1 nan
CHEMBL1487954 41094 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 5 2 4 3.0 CC1CCN(S(=O)(=O)c2ccc3[nH]cc(C(=O)NCc4ccc(F)cc4)c(=O)c3c2)CC1 nan
24260 41253 89 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 3 3 2.4 Nc1ccc(-c2nc3cc(N)ccc3[nH]2)cc1 nan
CHEMBL1489074 41253 89 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 3 3 2.4 Nc1ccc(-c2nc3cc(N)ccc3[nH]2)cc1 nan
3144653 41260 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 5 3.8 CCCNC(=O)CSc1nc(-c2ccc(OC)cc2)cc(C(F)(F)F)n1 nan
CHEMBL1489101 41260 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 5 3.8 CCCNC(=O)CSc1nc(-c2ccc(OC)cc2)cc(C(F)(F)F)n1 nan
5079958 41261 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 3 4.6 CCc1ccc(Sc2cc(C(=O)O)c3ccccc3n2)cc1 nan
CHEMBL1489124 41261 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 3 4.6 CCc1ccc(Sc2cc(C(=O)O)c3ccccc3n2)cc1 nan
16001343 41303 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 1 7 3.3 COc1cc(NC(=O)CSc2cc(=O)n(C)c3ccccc23)cc(OC)c1OC nan
CHEMBL1489463 41303 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 7 1 7 3.3 COc1cc(NC(=O)CSc2cc(=O)n(C)c3ccccc23)cc(OC)c1OC nan
1327191 41330 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 2 6 4.8 COc1ccc(OC)c(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
CHEMBL1489694 41330 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 2 6 4.8 COc1ccc(OC)c(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
3151460 41351 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.2 COCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1489888 41351 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 6 2 7 2.2 COCCCn1c(=N)c(C(=O)NC2CCCCC2)cc2c(=O)n3ccccc3nc21 nan
4282213 41415 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
CHEMBL1490341 41415 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 1 0 5 2.8 CC1CCCN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)C1 nan
28358990 41622 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
5451590 41622 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
CHEMBL1491733 41622 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 5 1 6 5.1 CCN1CCN(Cc2c(O)ccc3c(=O)c(Oc4ccccc4Cl)c(C(F)(F)F)oc23)CC1 nan
16025965 41702 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 10 1.4 CCOC(=O)c1cccc(NC(=O)c2cnc3sc(N4CCOCC4)nn3c2=O)c1 nan
CHEMBL1492345 41702 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 10 1.4 CCOC(=O)c1cccc(NC(=O)c2cnc3sc(N4CCOCC4)nn3c2=O)c1 nan
6157069 41769 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1OC nan
CHEMBL1492815 41769 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 3.5 COc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccco2)cc1OC nan
12005902 41806 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 10 4.1 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4nc5ccccc5s4)nn23)cc1OC nan
CHEMBL1493244 41806 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 7 1 10 4.1 COc1ccc(-c2nnc3ccc(SCC(=O)Nc4nc5ccccc5s4)nn23)cc1OC nan
16022789 41817 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)cc1C nan
CHEMBL1493335 41817 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 6 1 8 3.5 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3nc(-c4ccccc4)no3)c(=O)c3ccccc32)cc1C nan
2096572 41882 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.0 COc1ccc2c(C)cc(SCC(=O)Nc3ncc(Cl)cc3Cl)nc2c1 nan
CHEMBL1493965 41882 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 5 5.0 COc1ccc2c(C)cc(SCC(=O)Nc3ncc(Cl)cc3Cl)nc2c1 nan
16026311 42030 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(F)cc4C)c32)cc1 nan
CHEMBL1495516 42030 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(F)cc4C)c32)cc1 nan
4258482 42154 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 0 5 5.6 Cc1cccc(Cc2c(C)nc3nc(SCc4ccccc4Cl)nn3c2C)c1 nan
CHEMBL1496672 42154 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 0 5 5.6 Cc1cccc(Cc2c(C)nc3nc(SCc4ccccc4Cl)nn3c2C)c1 nan
17583888 42190 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 1 5 3.5 CCCc1cc(=O)oc2c(C)c(OCC(=O)Nc3ccccn3)ccc12 nan
CHEMBL1496919 42190 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 6 1 5 3.5 CCCc1cc(=O)oc2c(C)c(OCC(=O)Nc3ccccn3)ccc12 nan
3260315 42260 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 9 0.6 Cc1ccc(Cl)cc1NC(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1497548 42260 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 9 0.6 Cc1ccc(Cl)cc1NC(=O)COC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C nan
1488204 42550 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 4 0 5 5.3 O=S(=O)(c1ccccc1)c1cnc(-c2cccnc2)nc1-c1ccc(Cl)c(Cl)c1 nan
CHEMBL1500120 42550 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 4 0 5 5.3 O=S(=O)(c1ccccc1)c1cnc(-c2cccnc2)nc1-c1ccc(Cl)c(Cl)c1 nan
5309910 43081 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 2 7 2.2 CCOc1ccc(Cn2nnc(C(=O)NCc3ccc(OC)cc3)c2N)cc1 nan
CHEMBL1504868 43081 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 8 2 7 2.2 CCOc1ccc(Cn2nnc(C(=O)NCc3ccc(OC)cc3)c2N)cc1 nan
135422740 43129 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 5 1 7 4.8 Nc1c2cnnc-2nc(SCC(=O)c2ccc(Br)cc2)n1-c1ccc(Br)cc1 nan
CHEMBL1505277 43129 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 517 5 1 7 4.8 Nc1c2cnnc-2nc(SCC(=O)c2ccc(Br)cc2)n1-c1ccc(Br)cc1 nan
4975174 43680 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 1.2 COCCCn1c(C(=O)N2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
CHEMBL1510079 43680 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 1.2 COCCCn1c(C(=O)N2CCOCC2)cc2c(=O)n3ccccc3nc21 nan
6236457 43704 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 10 4.0 COc1cc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)cc(OC)c1OC nan
CHEMBL1510318 43704 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 523 7 1 10 4.0 COc1cc(C2C(C(=O)c3ccc4c(c3)CC(C)O4)=C(O)C(=O)N2c2nnc(C)s2)cc(OC)c1OC nan
135399378 43732 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 7 2.5 CCOc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
CHEMBL1510511 43732 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 7 2.5 CCOc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
16026527 43913 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.7 COc1ccc(CNC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)cc1 nan
CHEMBL1512255 43913 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.7 COc1ccc(CNC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)cc1 nan
16012611 43932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 4.8 Cc1nc2c(c(C)nn2C(C)(C)C)c(C)c1CCC(=O)Nc1ccc(F)cc1 nan
CHEMBL1512506 43932 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 4.8 Cc1nc2c(c(C)nn2C(C)(C)C)c(C)c1CCC(=O)Nc1ccc(F)cc1 nan
4405319 43963 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccc5ccccc45)nc3c2)cc1 nan
CHEMBL1512869 43963 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 4 6.3 CCOc1ccc(C(=O)Nc2ccc3oc(-c4cccc5ccccc45)nc3c2)cc1 nan
16024551 43990 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 7 4.4 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1513333 43990 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 7 1 7 4.4 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)cc1 nan
135416471 43997 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 Cc1ccc(-c2nc3c4ccccc4[nH]c(=O)n3n2)cc1 nan
CHEMBL1513443 43997 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 1 1 4 2.5 Cc1ccc(-c2nc3c4ccccc4[nH]c(=O)n3n2)cc1 nan
1306158 44019 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 5 5.2 COc1cc(OC)cc(C(=O)Nc2ccccc2-c2nc3ccccc3s2)c1 nan
CHEMBL1513732 44019 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 5 5.2 COc1cc(OC)cc(C(=O)Nc2ccccc2-c2nc3ccccc3s2)c1 nan
1887235 44055 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 5 4.8 COc1ccc(NC(=O)CCn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)cc1 nan
CHEMBL1514436 44055 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 5 4.8 COc1ccc(NC(=O)CCn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)cc1 nan
2158481 44067 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 2 1 5 4.1 Cc1cccc(NC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)c1C nan
CHEMBL1514582 44067 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 2 1 5 4.1 Cc1cccc(NC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)c1C nan
2134751 44068 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 10 1 8 4.5 O=C(CCCCCn1c(=O)c2sccc2n(Cc2ccccc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1514595 44068 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 10 1 8 4.5 O=C(CCCCCn1c(=O)c2sccc2n(Cc2ccccc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
7990486 44071 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 6 2.5 COc1cccc(CNC(=O)COC(=O)/C(C#N)=C/c2ccc(N(C)C)cc2)c1 nan
CHEMBL1514625 44071 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 8 1 6 2.5 COc1cccc(CNC(=O)COC(=O)/C(C#N)=C/c2ccc(N(C)C)cc2)c1 nan
16016989 44084 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.1 Cc1ccc(CNC(=O)C(C)n2nc(C)c3sc4ccccc4c3c2=O)cc1 nan
CHEMBL1514781 44084 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.1 Cc1ccc(CNC(=O)C(C)n2nc(C)c3sc4ccccc4c3c2=O)cc1 nan
4246910 44091 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 0 10 0.0 CCOCCn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1514858 44091 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 7 0 10 0.0 CCOCCn1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
16030776 44095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 10 1.9 Cc1cc(NC(=O)CSc2nc(-c3ccccc3F)nc3c2c(=O)n(C)c(=O)n3C)no1 nan
CHEMBL1514941 44095 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 10 1.9 Cc1cc(NC(=O)CSc2nc(-c3ccccc3F)nc3c2c(=O)n(C)c(=O)n3C)no1 nan
16022121 44118 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 4 0 7 2.9 COc1ccc2c(c1)c1c(c(=O)n(-c3cccc(Cl)c3)c(=O)n1CC(=O)N1CCCC1)n2C nan
CHEMBL1515298 44118 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 4 0 7 2.9 COc1ccc2c(c1)c1c(c(=O)n(-c3cccc(Cl)c3)c(=O)n1CC(=O)N1CCCC1)n2C nan
6418314 44124 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.4 CCC(Sc1nnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1)C(=O)NC1CCCC1 nan
CHEMBL1515335 44124 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 5 5.4 CCC(Sc1nnc(-c2ccc(F)cc2)c(-c2ccc(F)cc2)n1)C(=O)NC1CCCC1 nan
16031608 44134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)CC2)c(OC)c1 nan
CHEMBL1515521 44134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)CC2)c(OC)c1 nan
16014254 44141 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 2 6 3.2 NS(=O)(=O)c1ccc(CCNC(=O)c2nc(SCc3ccccc3F)ncc2Cl)cc1 nan
CHEMBL1515689 44141 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 8 2 6 3.2 NS(=O)(=O)c1ccc(CCNC(=O)c2nc(SCc3ccccc3F)ncc2Cl)cc1 nan
16009753 44152 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 1 0 5 3.8 Cn1c(=O)n(-c2ccc(Br)cc2F)c(=O)c2sc3ccccc3c21 nan
CHEMBL1515791 44152 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 1 0 5 3.8 Cn1c(=O)n(-c2ccc(Br)cc2F)c(=O)c2sc3ccccc3c21 nan
16029066 44164 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.0 CC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCCC3)cn2C)cc1 nan
CHEMBL1515983 44164 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.0 CC(=O)c1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCCCC3)cn2C)cc1 nan
16027656 44171 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 9 4.0 CC(C)Cc1nn2c(=O)cc(COC(=O)c3cccc(NC(=O)c4cccs4)c3)nc2s1 nan
CHEMBL1516060 44171 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 9 4.0 CC(C)Cc1nn2c(=O)cc(COC(=O)c3cccc(NC(=O)c4cccs4)c3)nc2s1 nan
16030468 44186 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3ccccc3n2)cc1C nan
CHEMBL1516233 44186 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3ccccc3n2)cc1C nan
15990035 44187 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 2 7 3.2 CC(C)CCNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1516237 44187 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 2 7 3.2 CC(C)CCNC(=O)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
6220215 44234 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C/c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
CHEMBL1516846 44234 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C/c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
3238933 44283 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 O=C(Nc1c(C(=O)Nc2cccc(F)c2)oc2ccccc12)c1ccc2c(c1)OCO2 nan
CHEMBL1517304 44283 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 2 5 4.8 O=C(Nc1c(C(=O)Nc2cccc(F)c2)oc2ccccc12)c1ccc2c(c1)OCO2 nan
24687299 44345 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.9 CC(=O)c1sc(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)nc1-c1ccccc1 nan
CHEMBL1517943 44345 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 3.9 CC(=O)c1sc(NC(=O)c2cccc(N3C(=O)CCC3=O)c2)nc1-c1ccccc1 nan
16009652 44361 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 2 4 5.8 O=C(Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12)c1cc2ccccc2o1 nan
CHEMBL1518097 44361 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 2 4 5.8 O=C(Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12)c1cc2ccccc2o1 nan
3298558 44401 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 7 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccccc2)CC1 nan
CHEMBL1518549 44401 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 7 3.7 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccccc2)CC1 nan
5286935 44416 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 2 4 2.4 Cc1ccc(NC(=O)/C(C#N)=C(\N)C(Cl)(Cl)Cl)nc1 nan
CHEMBL1518626 44416 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 2 4 2.4 Cc1ccc(NC(=O)/C(C#N)=C(\N)C(Cl)(Cl)Cl)nc1 nan
16031509 44464 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)s2)cc1 nan
CHEMBL1519036 44464 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 6 4.6 COc1ccc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)s2)cc1 nan
938163 44504 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 5 3.2 CC(=O)Nc1cccc(-c2nnc3c4ccccc4c(C)nn23)c1 nan
CHEMBL1519354 44504 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 2 1 5 3.2 CC(=O)Nc1cccc(-c2nnc3c4ccccc4c(C)nn23)c1 nan
2473851 44505 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 6 2.5 COc1cc(C(=O)NCCNC(=O)c2cc(OC)c(C)c(OC)c2)cc(OC)c1C nan
CHEMBL1519363 44505 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 6 2.5 COc1cc(C(=O)NCCNC(=O)c2cc(OC)c(C)c(OC)c2)cc(OC)c1C nan
24687548 44597 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 7 1 10 2.1 COc1ccc(OC)c(-c2csc(NC(=O)CSc3nnnn3C)n2)c1 nan
CHEMBL1520201 44597 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 7 1 10 2.1 COc1ccc(OC)c(-c2csc(NC(=O)CSc3nnnn3C)n2)c1 nan
1142116 44601 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 4 4.7 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccccc1 nan
CHEMBL1520265 44601 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 4 4.7 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccccc1 nan
2577415 44863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 0 8 2.4 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)c2csc(N3CCCCC3)n2)cc1 nan
CHEMBL1522536 44863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 0 8 2.4 CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)c2csc(N3CCCCC3)n2)cc1 nan
16027586 45028 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 3.6 CCc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1524058 45028 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 3.6 CCc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
22581682 45053 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 6 3.9 COc1ccc(-c2cn3nc(SCC(=O)NC4CCCCC4)ccc3n2)cc1 nan
CHEMBL1524339 45053 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 6 1 6 3.9 COc1ccc(-c2cn3nc(SCC(=O)NC4CCCCC4)ccc3n2)cc1 nan
2814763 45065 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 1 4.2 O=C(Nc1ccc(F)cc1)c1cc2cc(Cl)ccc2[nH]1 nan
CHEMBL1524425 45065 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 2 2 1 4.2 O=C(Nc1ccc(F)cc1)c1cc2cc(Cl)ccc2[nH]1 nan
16012570 45133 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccccc3Cl)c(C)nc21 nan
CHEMBL1525143 45133 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccccc3Cl)c(C)nc21 nan
3119681 45438 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 3 6.1 O=C(Cc1ccccc1)Nc1sc2c(c1C(=O)Nc1cccc(Cl)c1)CCCCC2 nan
CHEMBL1527765 45438 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 3 6.1 O=C(Cc1ccccc1)Nc1sc2c(c1C(=O)Nc1cccc(Cl)c1)CCCCC2 nan
3370309 45619 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 2 7 3.5 CCN(CCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)c1cccc(C)c1 nan
CHEMBL1529348 45619 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 9 2 7 3.5 CCN(CCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)c1cccc(C)c1 nan
3178487 45674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.8 CCn1c(SCC(=O)N2CCC(C)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1529806 45674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 8 0.8 CCn1c(SCC(=O)N2CCC(C)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
3161332 45927 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 5.4 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1ccccc1F nan
CHEMBL1532063 45927 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 5.4 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1ccccc1F nan
3787408 46030 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccc(C)cc2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
CHEMBL1532953 46030 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 7 5.3 CCCCn1c(NS(=O)(=O)c2ccc(C)cc2)c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc21 nan
2105095 46031 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 7 3.7 Cc1cc(NC(=O)CSc2nc3cc(Cl)ccc3c(=O)n2CC(C)C)no1 nan
CHEMBL1532957 46031 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 1 7 3.7 Cc1cc(NC(=O)CSc2nc3cc(Cl)ccc3c(=O)n2CC(C)C)no1 nan
2965497 46034 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 4 0 5 4.2 O=C(c1cc(-c2ccccn2)nc2ccc(Br)cc12)N1CCN(S(=O)(=O)c2ccccc2)CC1 nan
CHEMBL1532981 46034 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 4 0 5 4.2 O=C(c1cc(-c2ccccn2)nc2ccc(Br)cc12)N1CCN(S(=O)(=O)c2ccccc2)CC1 nan
16019855 46088 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 3.8 Cc1ccccc1-c1noc(-c2cc3ccccc3oc2=O)n1 nan
CHEMBL1533477 46088 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 2 0 5 3.8 Cc1ccccc1-c1noc(-c2cc3ccccc3oc2=O)n1 nan
17374586 46551 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 0 4 3.5 CCC(Oc1cc(Cl)ccc1Cl)C(=O)N1CCC2(CC1)OCCO2 nan
CHEMBL1537906 46551 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 0 4 3.5 CCC(Oc1cc(Cl)ccc1Cl)C(=O)N1CCC2(CC1)OCCO2 nan
1078178 46857 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 2 6 3.2 COc1cc(OC)cc(C(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)c1 nan
CHEMBL1540495 46857 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 2 6 3.2 COc1cc(OC)cc(C(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)c1 nan
721260 46891 38 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 2 1 5 1.7 CCOC(=O)c1cc(C#N)c(S)nc1C nan
CHEMBL1540818 46891 38 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 222 2 1 5 1.7 CCOC(=O)c1cc(C#N)c(S)nc1C nan
657993 46903 14 None -31 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 1 4 3.4 COc1ccc(-c2c(C#N)c(S)nc3c2CCC3)cc1 nan
CHEMBL1540912 46903 14 None -31 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 282 2 1 4 3.4 COc1ccc(-c2c(C#N)c(S)nc3c2CCC3)cc1 nan
1356173 47351 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 2 4 4.8 CCOC(=O)c1c(N=C(S)Nc2ccc(C)cc2)sc2c1CCC2 nan
CHEMBL1544543 47351 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 2 4 4.8 CCOC(=O)c1c(N=C(S)Nc2ccc(C)cc2)sc2c1CCC2 nan
16195345 47481 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 2 8 0.4 Cn1c(=O)c2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)NCC3CCCO3)ccc2n(C)c1=O nan
CHEMBL1545503 47481 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 2 8 0.4 Cn1c(=O)c2cc(S(=O)(=O)NC(Cc3ccccc3)C(=O)NCC3CCCO3)ccc2n(C)c1=O nan
2868878 47496 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 4.1 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1cccc(F)c1 nan
CHEMBL1545607 47496 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 4.1 CC(=O)C1=C(O)C(=O)N(c2ccc(Br)cc2)C1c1cccc(F)c1 nan
3186499 47516 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 8 3.5 CCc1nnc(NC(=O)CSc2nc3cc4c(cc3cc2C)OCCO4)s1 nan
CHEMBL1545790 47516 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 1 8 3.5 CCc1nnc(NC(=O)CSc2nc3cc4c(cc3cc2C)OCCO4)s1 nan
1485832 47584 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 1 4 4.6 O=C(Nc1ccccc1)c1cc2c(=O)c3ccccc3oc2nc1C(F)(F)F nan
CHEMBL1546403 47584 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 2 1 4 4.6 O=C(Nc1ccccc1)c1cc2c(=O)c3ccccc3oc2nc1C(F)(F)F nan
24892595 47763 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 7 3.8 COCCn1c(SCC(=O)Nc2cccc(F)c2)nc2c3ccccc3nc-2c1O nan
CHEMBL1548166 47763 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 2 7 3.8 COCCn1c(SCC(=O)Nc2cccc(F)c2)nc2c3ccccc3nc-2c1O nan
4223534 47783 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 2 4.5 CC1(C)C(CSc2nc3ccccc3[nH]2)C1(Cl)Cl nan
CHEMBL1548301 47783 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 2 4.5 CC1(C)C(CSc2nc3ccccc3[nH]2)C1(Cl)Cl nan
818439 47859 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 1 2 7 1.1 COC(=O)c1sc2nc(N)c(C#N)cc2c1N nan
CHEMBL1548988 47859 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 1 2 7 1.1 COC(=O)c1sc2nc(N)c(C#N)cc2c1N nan
1417035 47930 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 8 1.0 Cn1c(=O)c2c(nc(SCc3ccc(C(=O)O)cc3)n2C)n(C)c1=O nan
CHEMBL1549569 47930 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 4 1 8 1.0 Cn1c(=O)c2c(nc(SCc3ccc(C(=O)O)cc3)n2C)n(C)c1=O nan
1838684 47962 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 4.3 O=C(COc1ccc(Cl)cc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
CHEMBL1549821 47962 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 6 4.3 O=C(COc1ccc(Cl)cc1)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 nan
1777240 48115 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 5 2.3 Cc1cc(OCC(=O)N2CCC(C(=O)O)CC2)c2c3c(c(=O)oc2c1)CCC3 nan
CHEMBL1551078 48115 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 5 2.3 Cc1cc(OCC(=O)N2CCC(C(=O)O)CC2)c2c3c(c(=O)oc2c1)CCC3 nan
16009855 48159 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 5 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)Nc1ccc(F)cc1F nan
CHEMBL1551826 48159 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 5 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)Nc1ccc(F)cc1F nan
16030710 48165 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 5 1 9 3.3 COC(=O)c1ccc(NC(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccc(C)cc5)sc4n3)CC2)cc1 nan
CHEMBL1551878 48165 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 5 1 9 3.3 COC(=O)c1ccc(NC(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccc(C)cc5)sc4n3)CC2)cc1 nan
1004076 48168 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4C)sc3n2)cc1 nan
CHEMBL1551914 48168 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 2 5 5.3 COc1ccc(-c2ccc3c(N)c(C(=O)Nc4cc(F)ccc4C)sc3n2)cc1 nan
7222625 48229 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 6 4.4 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(C)c(F)c3)nn2)s1 nan
CHEMBL1552706 48229 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 6 4.4 Cc1nc(C)c(-c2ccc(SCC(=O)Nc3ccc(C)c(F)c3)nn2)s1 nan
16010352 48265 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 4 4.6 CCOC(=O)c1c(C)c(-c2ccccc2)n(CC(=O)NCCc2cccc(C)c2)c1C nan
CHEMBL1553141 48265 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 4 4.6 CCOC(=O)c1c(C)c(-c2ccccc2)n(CC(=O)NCCc2cccc(C)c2)c1C nan
16030832 48319 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 1 4 4.2 O=C(Nc1ccccc1C(=O)N1CCCCC1)c1nsc2ccccc12 nan
CHEMBL1553983 48319 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 1 4 4.2 O=C(Nc1ccccc1C(=O)N1CCCCC1)c1nsc2ccccc12 nan
16012075 48325 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 4.2 CC(=O)c1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)cc1 nan
CHEMBL1554061 48325 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 6 4.2 CC(=O)c1ccc(NC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)cc1 nan
16008778 48327 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 9 1.9 CCOC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)ccc21 nan
CHEMBL1554084 48327 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 7 0 9 1.9 CCOC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N3CCN(c4ccc(C(C)=O)cc4)CC3)ccc21 nan
3147967 48331 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.6 Cc1cccc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)c1 nan
CHEMBL1554132 48331 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.6 Cc1cccc(NC(=O)CSc2nnc3c4ccccc4n(C)c3n2)c1 nan
1222858 48338 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 8 3.3 COC(=O)c1sc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c(C(=O)OC)c1C nan
CHEMBL1554200 48338 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 8 3.3 COC(=O)c1sc(NC(=O)/C=C/c2ccc(OC)c(OC)c2)c(C(=O)OC)c1C nan
16027476 48339 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 nan
CHEMBL1554206 48339 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 nan
15989095 48340 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 7 2.2 NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1554211 48340 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 7 2.2 NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
15991109 48345 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1ccc(F)cc1F nan
CHEMBL1554314 48345 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 3 5.2 Cc1ccc2c(c1)c(=O)c1ccccc1n2CCCC(=O)Nc1ccc(F)cc1F nan
3503858 48353 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 6 5.3 CCC(C)NC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1Cc1ccccc1Cl nan
CHEMBL1554470 48353 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 1 6 5.3 CCC(C)NC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1Cc1ccccc1Cl nan
16024920 48388 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 5 5.0 CCCOc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1555031 48388 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 1 5 5.0 CCCOc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16009072 48396 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 2.8 CCOc1ccc(S(=O)(=O)c2c[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1555115 48396 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 2.8 CCOc1ccc(S(=O)(=O)c2c[nH]c3ccccc3c2=O)cc1 nan
16015125 48399 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1C nan
CHEMBL1555140 48399 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 1 5 4.6 Cc1ccc(OCC(=O)Nc2nc(-c3ccc(Br)cc3)ns2)cc1C nan
9550626 48442 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 7 3.9 CCOC(=O)c1c(NC(=O)c2cc(CC(C)C)on2)sc(C(C)=O)c1C nan
CHEMBL1555685 48442 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 7 3.9 CCOC(=O)c1c(NC(=O)c2cc(CC(C)C)on2)sc(C(C)=O)c1C nan
2176795 48483 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 5 3.8 Cc1onc(-c2ccccc2Cl)c1C(=O)NC(=S)NCC(=O)c1ccccc1 nan
CHEMBL1556085 48483 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 2 5 3.8 Cc1onc(-c2ccccc2Cl)c1C(=O)NC(=S)NCC(=O)c1ccccc1 nan
16022893 48618 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.8 Cc1ccc(-n2nc3c(N4CCC(C(=O)NC(C)c5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1557305 48618 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 1 6 4.8 Cc1ccc(-n2nc3c(N4CCC(C(=O)NC(C)c5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
16011715 48686 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 6 2.9 Cc1cc(F)ccc1Nc1nc2ccccc2n2nnnc12 nan
CHEMBL1557862 48686 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 2 1 6 2.9 Cc1cc(F)ccc1Nc1nc2ccccc2n2nnnc12 nan
15989730 48691 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 3.6 Cc1cc(C)cc(Nc2nc3ccccc3n3cnnc23)c1 nan
CHEMBL1557912 48691 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 3.6 Cc1cc(C)cc(Nc2nc3ccccc3n3cnnc23)c1 nan
16011441 48776 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.9 COc1ccc(Cn2c(SCc3ccc(C(=O)NCc4ccccc4F)cc3)nc3cccnc32)cc1 nan
CHEMBL1558654 48776 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.9 COc1ccc(Cn2c(SCc3ccc(C(=O)NCc4ccccc4F)cc3)nc3cccnc32)cc1 nan
16030801 48815 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.4 COc1ccc(-c2cc3ccc(O)c(CN4CCCC(C)C4)c3oc2=O)cc1 nan
CHEMBL1558940 48815 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 4.4 COc1ccc(-c2cc3ccc(O)c(CN4CCCC(C)C4)c3oc2=O)cc1 nan
1970873 48818 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(F)cc5)s4)c3nc12 nan
CHEMBL1558965 48818 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccc(F)cc5)s4)c3nc12 nan
16024619 48833 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 4.3 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1559093 48833 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 4.3 CCOC(=O)c1ccc(NC(=O)Cn2cc(C(=O)c3ccc(CC)cc3)c(=O)c3ccc(C)nc32)cc1 nan
135448823 48936 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 2.7 Cc1cc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)no1 nan
CHEMBL1560048 48936 12 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 8 2.7 Cc1cc(NC(=O)CSc2nc(O)c(C#N)c(-c3ccccc3)n2)no1 nan
20944767 49039 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 3.3 O=C(CN1c2ccccc2S(=O)(=O)c2ccccc21)NCc1ccccc1 nan
CHEMBL1561113 49039 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 4 3.3 O=C(CN1c2ccccc2S(=O)(=O)c2ccccc21)NCc1ccccc1 nan
938228 49066 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1cccc(-c2cc(-c3cccnc3)nc(N)c2C#N)c1 nan
CHEMBL1561334 49066 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 1 5 3.3 COc1cccc(-c2cc(-c3cccnc3)nc(N)c2C#N)c1 nan
2136514 49295 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1563400 49295 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
16195481 49338 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 3 8 2.2 COc1cc2nc(S)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2cc1OC nan
CHEMBL1563755 49338 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 3 8 2.2 COc1cc2nc(S)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2cc1OC nan
16010206 49483 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
CHEMBL1565063 49483 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
16017589 49705 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 7 1.5 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Cl nan
CHEMBL1566733 49705 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 4 1 7 1.5 O=C(Nc1nnc(S(=O)(=O)N2CCOCC2)s1)c1ccccc1Cl nan
2764046 49709 52 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 3 4.8 O=C(O)Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1 nan
CHEMBL1566761 49709 52 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 3 4.8 O=C(O)Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1 nan
1419199 49728 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1419200 49728 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
CHEMBL1566925 49728 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 516 6 1 5 4.6 O=C(O)CCCC(=O)N1CCN(c2nc(-c3ccccc3Cl)c3cc(Br)ccc3n2)CC1 nan
1101443 49816 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1ccc2oc(-c3cccc(F)c3)nc2c1)c1ccccc1F nan
CHEMBL1567607 49816 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1ccc2oc(-c3cccc(F)c3)nc2c1)c1ccccc1F nan
663542 49929 15 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(F)c1 nan
CHEMBL1568508 49929 15 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 1 5 4.2 O=C(CSc1ncnc2c1oc1ccccc12)Nc1cccc(F)c1 nan
2837061 49934 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 3 4.9 O=C(Nc1cccc(NC(=O)c2ccc(Cl)cc2)n1)c1ccc(Cl)cc1 nan
CHEMBL1568556 49934 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 2 3 4.9 O=C(Nc1cccc(NC(=O)c2ccc(Cl)cc2)n1)c1ccc(Cl)cc1 nan
6618042 49945 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 6 3.5 CCCCn1c(=O)nc2n(-c3ccc(OC)cc3)c3ccccc3cc-2c1=O nan
CHEMBL1568603 49945 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 6 3.5 CCCCn1c(=O)nc2n(-c3ccc(OC)cc3)c3ccccc3cc-2c1=O nan
648080 50008 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 3.6 COc1ccc2cc(C)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
CHEMBL1569235 50008 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 3.6 COc1ccc2cc(C)c(SCC(=O)Nc3cc(C)on3)nc2c1 nan
2726812 50053 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 0 4 3.4 COC(=O)c1cc2cc(Cl)ccc2nc1SC nan
CHEMBL1569571 50053 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 0 4 3.4 COC(=O)c1cc2cc(Cl)ccc2nc1SC nan
802608 50197 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 2 4.3 COc1ccc(Br)cc1C(=O)Nc1cccc(C)c1C nan
CHEMBL1570796 50197 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 2 4.3 COc1ccc(Br)cc1C(=O)Nc1cccc(C)c1C nan
1247683 50218 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.2 Cc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c(C)o1 nan
CHEMBL1570956 50218 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.2 Cc1cc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c(C)o1 nan
2874268 50270 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 5 3.0 Cc1cc(NCCCN(C)C)n2c(nc3ccccc32)c1C#N nan
CHEMBL1571576 50270 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 5 3.0 Cc1cc(NCCCN(C)C)n2c(nc3ccccc32)c1C#N nan
15988316 50284 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 2.7 CCOC(=O)c1ccc(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1571739 50284 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 2.7 CCOC(=O)c1ccc(NC(=O)COC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1 nan
6037218 50355 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
CHEMBL1572317 50355 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.6 COc1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2Cc2cccnc2)cc1 nan
995077 50440 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 4 4.3 Cn1cc(CNC(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cn1 nan
CHEMBL1573031 50440 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 1 4 4.3 Cn1cc(CNC(=O)c2cc(-c3ccccc3)nc3ccc(Br)cc23)cn1 nan
1927600 50540 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 8 2 5 7.1 CCc1ccccc1NC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1574096 50540 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 8 2 5 7.1 CCc1ccccc1NC(=O)CSc1nc(C)c(C(=O)Nc2ccccc2)c(-c2ccc(Cl)cc2)c1C#N nan
857532 50549 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.3 CCc1cc2cccc(C)c2nc1SCC(=O)NC1CCCC1 nan
CHEMBL1574178 50549 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.3 CCc1cc2cccc(C)c2nc1SCC(=O)NC1CCCC1 nan
7206308 50572 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 3.1 O=C(CSc1ccc(-c2ccc3c(c2)OCO3)nn1)Nc1nccs1 nan
CHEMBL1574382 50572 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 8 3.1 O=C(CSc1ccc(-c2ccc3c(c2)OCO3)nn1)Nc1nccs1 nan
2906920 50743 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 4.3 O=C(Nc1ccc(N2C(=O)C3CCCCC3C2=O)cc1Cl)c1cccs1 nan
CHEMBL1576225 50743 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 4.3 O=C(Nc1ccc(N2C(=O)C3CCCCC3C2=O)cc1Cl)c1cccs1 nan
135444827 50752 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 3.0 COc1cccc(N2CC(=O)C(c3nc4ccccc4s3)=C2N)c1 nan
CHEMBL1576321 50752 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 3.0 COc1cccc(N2CC(=O)C(c3nc4ccccc4s3)=C2N)c1 nan
4099135 50820 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1cccc(Cl)c1 nan
CHEMBL1576790 50820 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 9 2 6 4.4 O=C(CCCCCn1c(=S)[nH]c2ccc(N3CCOCC3)cc2c1=O)NCc1cccc(Cl)c1 nan
652081 51025 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4cccnc4)c3nc12 nan
CHEMBL1578543 51025 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 2 8 1.8 Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)c(=N)n(Cc4cccnc4)c3nc12 nan
2040375 51049 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 0 6 4.7 COc1cc2oc(=O)c3c(c2cc1OCC(=O)c1c(C)n(C)c2ccccc12)CCCC3 nan
CHEMBL1578721 51049 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 0 6 4.7 COc1cc2oc(=O)c3c(c2cc1OCC(=O)c1c(C)n(C)c2ccccc12)CCCC3 nan
5100816 51204 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 10 2 6 3.0 O=C(COC(=O)c1cccnc1SCC(=O)NCc1ccccc1)NCc1ccccc1 nan
CHEMBL1580143 51204 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 10 2 6 3.0 O=C(COC(=O)c1cccnc1SCC(=O)NCc1ccccc1)NCc1ccccc1 nan
2823757 51743 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 2 4.4 CC(C)(C)c1ccc(C(=O)Nc2ccc(F)cc2)s1 nan
CHEMBL1584690 51743 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 1 2 4.4 CC(C)(C)c1ccc(C(=O)Nc2ccc(F)cc2)s1 nan
1447358 51956 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 6 1.7 CC(C)C(=O)NNC(=O)CN1CCN(c2nc(-c3ccccc3)cs2)CC1 nan
CHEMBL1586366 51956 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 5 2 6 1.7 CC(C)C(=O)NNC(=O)CN1CCN(c2nc(-c3ccccc3)cs2)CC1 nan
2123807 52131 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 7 0.9 COc1ccc(C(=O)Nc2cccc3c2C(=O)NC3=O)cc1S(=O)(=O)N1CCOCC1 nan
CHEMBL1587750 52131 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 7 0.9 COc1ccc(C(=O)Nc2cccc3c2C(=O)NC3=O)cc1S(=O)(=O)N1CCOCC1 nan
2639566 52340 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.1 COc1ccc(C(=O)COc2ccc3ccc(=O)oc3c2)c(OC)c1 nan
CHEMBL1589654 52340 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 0 6 3.1 COc1ccc(C(=O)COc2ccc3ccc(=O)oc3c2)c(OC)c1 nan
16027668 52369 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 8 3.4 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1589886 52369 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 6 1 8 3.4 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
16027394 52378 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 1 8 3.4 Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
CHEMBL1589930 52378 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 1 8 3.4 Cc1nn2c(=O)cc(COC(=O)c3ccc(NC(=O)CCc4ccccc4)cc3)nc2s1 nan
16007616 52394 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 5 3.6 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(F)cc1)cn2C nan
CHEMBL1590166 52394 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 5 3.6 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCc1ccc(F)cc1)cn2C nan
16018888 52411 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 0 5 5.2 Cc1nnc(SCc2ccccc2Cl)c2cc3sccc3n12 nan
CHEMBL1590393 52411 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 0 5 5.2 Cc1nnc(SCc2ccccc2Cl)c2cc3sccc3n12 nan
2058614 52414 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1cc(C)cc(C)c1 nan
CHEMBL1590410 52414 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(Cc2ccco2)/c1=N\C(=O)c1cc(C)cc(C)c1 nan
16025295 52425 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.8 CCc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
CHEMBL1590637 52425 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 7 1 6 5.8 CCc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)c1 nan
16017896 52465 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 0 7 2.7 COc1ccc(N2CCN(C(=O)c3sc4nc5n(c(=O)c4c3C)CCC5)CC2)cc1 nan
CHEMBL1591031 52465 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 0 7 2.7 COc1ccc(N2CCN(C(=O)c3sc4nc5n(c(=O)c4c3C)CCC5)CC2)cc1 nan
16024829 52503 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 1 4 4.6 O=C(Nc1ccc(F)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1591484 52503 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 3 1 4 4.6 O=C(Nc1ccc(F)cc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
16027514 52514 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)c1 nan
CHEMBL1591656 52514 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)c2)c1 nan
16012296 52521 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1cccc(NC(=O)c2ccc(-c3ccccc3)s2)c1 nan
CHEMBL1591740 52521 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1cccc(NC(=O)c2ccc(-c3ccccc3)s2)c1 nan
16019608 52571 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 8 3.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2sccc23)cc1 nan
CHEMBL1592430 52571 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 8 3.3 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)C)c2sccc23)cc1 nan
135546866 52627 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 4 3.7 Cc1ccc(NC(=O)C(C)Sc2nc3c(c(=O)[nH]2)CCCC3)cc1Cl nan
CHEMBL1593216 52627 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 4 3.7 Cc1ccc(NC(=O)C(C)Sc2nc3c(c(=O)[nH]2)CCCC3)cc1Cl nan
3955100 52633 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 7 4.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)ccc3OC)o2)cc1 nan
CHEMBL1593290 52633 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 7 4.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)ccc3OC)o2)cc1 nan
16019825 52650 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 2 4 3.2 Cc1ccc(C)c(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)c1 nan
CHEMBL1593576 52650 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 2 4 3.2 Cc1ccc(C)c(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)c1 nan
7598919 52844 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 5 3.5 CCOC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3F)c2=O)cc1 nan
CHEMBL1595394 52844 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 5 3.5 CCOC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3F)c2=O)cc1 nan
2135415 52879 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 6 2.0 Cc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)cc1 nan
CHEMBL1595713 52879 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 6 2.0 Cc1ccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)cc1 nan
15988650 52926 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 5 5.6 Cc1cc(NC(=O)c2cc(-c3ccc(Br)cc3)on2)nn1Cc1ccc(Cl)cc1 nan
CHEMBL1596161 52926 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 5 5.6 Cc1cc(NC(=O)c2cc(-c3ccc(Br)cc3)on2)nn1Cc1ccc(Cl)cc1 nan
16009387 52945 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 1 7 3.9 O=C(Cn1cc(S(=O)(=O)c2ccc(Cl)cc2)c(=O)c2ccccc21)Nc1ccc2c(c1)OCO2 nan
CHEMBL1596294 52945 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 5 1 7 3.9 O=C(Cn1cc(S(=O)(=O)c2ccc(Cl)cc2)c(=O)c2ccccc21)Nc1ccc2c(c1)OCO2 nan
16028259 52969 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 6 3.0 CCOc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccc(F)cc4)ccn3n2)cc1 nan
CHEMBL1596560 52969 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 6 3.0 CCOc1ccc(-c2cc3c(=O)n(CC(=O)NCc4ccc(F)cc4)ccn3n2)cc1 nan
1450700 52983 2 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCCO3 nan
CHEMBL1596663 52983 2 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCCO3 nan
859504 53001 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 0 6 3.3 Cc1cc2cc3c(cc2nc1SCC(=O)OC(C)C)OCO3 nan
CHEMBL1596835 53001 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 0 6 3.3 Cc1cc2cc3c(cc2nc1SCC(=O)OC(C)C)OCO3 nan
20903879 53013 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)c1 nan
CHEMBL1596921 53013 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 8 1.7 CC(=O)c1cccc(NC(=O)CCc2nnc3ccc(N4CCN(C)CC4)nn23)c1 nan
5922522 53075 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 9 1 6 4.7 CCCCOc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccncc2)c(C)c1 nan
CHEMBL1597564 53075 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 9 1 6 4.7 CCCCOc1ccc(C(=O)C2=C(O)C(=O)N(Cc3cccnc3)C2c2ccncc2)c(C)c1 nan
16031965 53080 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 2 6 4.1 COc1ccc(-c2nc(C)c(CCNC(=O)C(=O)Nc3c(C)cccc3C)s2)cc1OC nan
CHEMBL1597608 53080 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 2 6 4.1 COc1ccc(-c2nc(C)c(CCNC(=O)C(=O)Nc3c(C)cccc3C)s2)cc1OC nan
4656755 53100 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.9 COc1ccc(C(=O)Nc2cc(C)c3c(=O)oc4ccccc4c3n2)cc1 nan
CHEMBL1597754 53100 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.9 COc1ccc(C(=O)Nc2cc(C)c3c(=O)oc4ccccc4c3n2)cc1 nan
16030399 53120 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 4 4.9 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCC(C)CC2)cc1 nan
CHEMBL1597953 53120 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 0 4 4.9 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCC(C)CC2)cc1 nan
23603072 53264 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 0 7 0.7 CC1CCCN(C(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)C1 nan
CHEMBL1599245 53264 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 0 7 0.7 CC1CCCN(C(=O)CCS(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)C1 nan
16009708 53415 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 5 5.0 COc1ccc(CC(=O)Nc2c(C(=O)Nc3ccc(F)cc3)oc3ccccc23)cc1OC nan
CHEMBL1600646 53415 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 5 5.0 COc1ccc(CC(=O)Nc2c(C(=O)Nc3ccc(F)cc3)oc3ccccc23)cc1OC nan
1093818 53488 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1)c1cc(-c2ccc(Cl)cc2Cl)on1 nan
CHEMBL1601278 53488 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 3 1 4 4.3 O=C(Nc1cccnc1)c1cc(-c2ccc(Cl)cc2Cl)on1 nan
4327872 53572 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 0 6 1.4 CC1CN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC(C)O1 nan
CHEMBL1602225 53572 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 1 0 6 1.4 CC1CN(C(=O)c2cc3c(=O)n4ccccc4nc3n2C)CC(C)O1 nan
7199971 53726 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 8 3.5 Cc1ccc(-n2ncc3c(SCC(=O)Nc4cc(C)on4)ncnc32)c(C)c1 nan
CHEMBL1603605 53726 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 8 3.5 Cc1ccc(-n2ncc3c(SCC(=O)Nc4cc(C)on4)ncnc32)c(C)c1 nan
22522531 53734 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 1 4 3.5 CCc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
CHEMBL1603663 53734 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 1 4 3.5 CCc1cccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
7763635 53824 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 0 7 1.7 COc1ccc(C(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)c(OC)c1 nan
CHEMBL1604328 53824 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 0 7 1.7 COc1ccc(C(=O)COC(=O)CN2C(=O)c3ccccc3C2=O)c(OC)c1 nan
1072346 53937 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.5 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1nccs1 nan
CHEMBL1605363 53937 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 6 4.5 O=C(CSc1nc(-c2ccccc2)nc2ccccc12)Nc1nccs1 nan
1005145 53974 14 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.6 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCC2 nan
CHEMBL1605614 53974 14 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 1 6 3.6 N#Cc1cc2c(nc1SCC(=O)Nc1sc3c(c1C#N)CCC3)CCC2 nan
15991041 54028 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 3 5.7 CCCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)c(Br)c2)cc1 nan
CHEMBL1606046 54028 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 2 3 5.7 CCCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)c(Br)c2)cc1 nan
2934348 54188 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 2 6 3.4 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccc(O)c1)c1ccco1 nan
CHEMBL1607257 54188 21 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 2 6 3.4 O=C(C1=C(O)C(=O)N(Cc2ccco2)C1c1cccc(O)c1)c1ccco1 nan
16027345 54254 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 4.4 CCCNC(=O)Cn1nc(-c2ccc(C)c(C)c2)c2cnc3ccc(OC)cc3c21 nan
CHEMBL1607743 54254 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 4.4 CCCNC(=O)Cn1nc(-c2ccc(C)c(C)c2)c2cnc3ccc(OC)cc3c21 nan
753354 54264 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 0 6 2.6 O=C1c2ccccc2C(=O)N1c1nc2nccc(-c3ccccc3)n2n1 nan
CHEMBL1607842 54264 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 2 0 6 2.6 O=C1c2ccccc2C(=O)N1c1nc2nccc(-c3ccccc3)n2n1 nan
3512516 54397 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 7 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
CHEMBL1609027 54397 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 2 7 4.2 CCOc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)cc1 nan
16011054 54411 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 6 4.0 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Cl)c4)ncn32)s1 nan
CHEMBL1609118 54411 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 6 4.0 CCc1cc2c(cc3c(=O)n(CCCC(=O)NCc4cccc(Cl)c4)ncn32)s1 nan
2422324 54516 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 3 8 -0.1 COCCn1c(N)c(C(=S)NC(=O)c2cccs2)c(=O)[nH]c1=O nan
CHEMBL1609964 54516 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 5 3 8 -0.1 COCCn1c(N)c(C(=S)NC(=O)c2cccs2)c(=O)[nH]c1=O nan
16007504 54574 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.2 COc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1610456 54574 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 6 1 4 5.2 COc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
2134793 54583 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 0 6 5.6 COCCCn1c(SCc2cccc(Cl)c2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1610529 54583 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 0 6 5.6 COCCCn1c(SCc2cccc(Cl)c2)nc2c(sc3ccccc32)c1=O nan
3374134 54610 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 4 2.4 O=C(Cn1c(=S)[nH]c2ccccc2c1=O)NCCc1ccccc1 nan
CHEMBL1610861 54610 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 4 2.4 O=C(Cn1c(=S)[nH]c2ccccc2c1=O)NCCc1ccccc1 nan
3185781 54698 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 10 3 8 2.2 COCCN(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCCC1)c1ccc(N(C)C)cc1 nan
CHEMBL1611537 54698 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 10 3 8 2.2 COCCN(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCCC1)c1ccc(N(C)C)cc1 nan
3353363 54711 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 6 4.1 COc1ccc(C2CC(=O)c3cnc(N4CCc5ccccc54)nc3C2)cc1OC nan
CHEMBL1611722 54711 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 6 4.1 COc1ccc(C2CC(=O)c3cnc(N4CCc5ccccc54)nc3C2)cc1OC nan
2201483 55662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
5739455 55662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
9587736 55662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
CHEMBL1442349 55662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
CHEMBL1621693 55662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 4 7 2.8 Cc1cc(C)nc(NC(=N)Nc2ccc(S(=O)(=O)Nc3nc(C)cc(C)n3)cc2)n1 nan
354678 55847 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL1518154 55847 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
CHEMBL1623188 55847 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 1.6 CCC1(OC(=O)CN)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 nan
24792219 55979 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
CHEMBL1551405 55979 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
CHEMBL1624286 55979 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 7 1 4 6.5 Fc1ccc(-[n+]2nc(Nc3ccccc3)sc2-c2ccc(OCc3ccccc3)cc2)cc1 nan
3490356 72458 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 5 2.2 C#CCn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
CHEMBL1988684 72458 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 3 0 5 2.2 C#CCn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
1522244 85493 79 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 164 0 1 3 1.9 Cn1c(S)nc2ccccc21 nan
CHEMBL227086 85493 79 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 164 0 1 3 1.9 Cn1c(S)nc2ccccc21 nan
25252625 107615 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 6 1 5 1.8 COc1ccc(CC(=O)N/N=C/c2cccnc2)cc1OC nan
CHEMBL3189886 107615 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 6 1 5 1.8 COc1ccc(CC(=O)N/N=C/c2cccnc2)cc1OC nan
9701594 107771 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 6 2.1 O=C(N/N=C1\C/C(=N\NC(=O)c2ccncc2)c2ccccc21)c1ccncc1 nan
CHEMBL3191689 107771 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 6 2.1 O=C(N/N=C1\C/C(=N\NC(=O)c2ccncc2)c2ccccc21)c1ccncc1 nan
4141152 108866 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 5 2.6 CCOC(=O)c1s/c(=N\C(=O)c2cccc(C)c2)n(C)c1C nan
CHEMBL3210377 108866 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 0 5 2.6 CCOC(=O)c1s/c(=N\C(=O)c2cccc(C)c2)n(C)c1C nan
2150923 109069 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 3.1 CCn1/c(=N/C(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3212992 109069 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 0 7 3.1 CCn1/c(=N/C(=O)c2cccc(N3C(=O)CCC3=O)c2)sc2c(OC)ccc(OC)c21 nan
1477780 199079 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 1 6 3.0 COc1cc(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)cc(OC)c1OC nan
CHEMBL587856 199079 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 1 6 3.0 COc1cc(-c2nc3ccc(N4CCN(C)CC4)cc3[nH]2)cc(OC)c1OC nan
7190643 21056 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1311897 21056 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 7 3.2 Cc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
1739479 21401 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 6.0 Cc1cc(Br)cc2c(C(=O)OCC(=O)c3ccccc3)cc(-c3ccccc3)nc12 nan
CHEMBL1314681 21401 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 0 4 6.0 Cc1cc(Br)cc2c(C(=O)OCC(=O)c3ccccc3)cc(-c3ccccc3)nc12 nan
15988299 21798 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
CHEMBL1319322 21798 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 7 2.9 Cn1c(=O)c2sccc2n2c(CCCC(=O)Nc3ccc(F)cc3F)nnc12 nan
4146227 26900 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1363837 26900 11 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 7 5.6 CCOC(=O)c1ccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)cc1 nan
15988966 30860 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 10 1 4 6.5 CC(C)CN(CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12)CC(C)C nan
CHEMBL1397188 30860 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 10 1 4 6.5 CC(C)CN(CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12)CC(C)C nan
1398096 31200 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 7 2 5 2.8 CC(C)c1nnc(NC(=O)CCC(=O)NCc2ccc(F)cc2)s1 nan
CHEMBL1400798 31200 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 7 2 5 2.8 CC(C)c1nnc(NC(=O)CCC(=O)NCc2ccc(F)cc2)s1 nan
24792315 31536 2 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 9 1.9 CCc1nnc(NC(=O)CSc2nnc3nc(C)cc(C)n23)s1 nan
CHEMBL1403815 31536 2 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 9 1.9 CCc1nnc(NC(=O)CSc2nnc3nc(C)cc(C)n23)s1 nan
15991483 39579 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 0 6 6.1 CCOc1ccc(-c2nnc(SCC(=O)c3ccc(Br)cc3)n2-c2ccccc2)cc1 nan
CHEMBL1473564 39579 7 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 8 0 6 6.1 CCOc1ccc(-c2nnc(SCC(=O)c3ccc(Br)cc3)n2-c2ccccc2)cc1 nan
4299978 43856 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 9 1.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nnc2ccccn12 nan
CHEMBL1511455 43856 6 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 9 1.5 COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CSc1nnc2ccccn12 nan
16019368 52677 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 10 4.5 COc1cc(Nc2nc3c(S(=O)(=O)c4ccc(C)c(C)c4)nnn3c3ccsc23)cc(OC)c1 nan
CHEMBL1593977 52677 9 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 10 4.5 COc1cc(Nc2nc3c(S(=O)(=O)c4ccc(C)c(C)c4)nnn3c3ccsc23)cc(OC)c1 nan
814542 53106 25 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 0 2 3 2.7 Cc1ccc2[nH]c3c(S)ncnc3c2c1 nan
CHEMBL1597829 53106 25 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 215 0 2 3 2.7 Cc1ccc2[nH]c3c(S)ncnc3c2c1 nan
9619102 72442 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 11 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1OC nan
CHEMBL1988156 72442 8 None - 1 Human 5.5 pPotency = 5.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 11 -0.4 COc1ccc(/C=N/NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(OC)c1OC nan
16010435 6198 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 8 5.0 COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(C)c(C)c3)nnn2c2ccc(Cl)cc12 nan
CHEMBL1081265 6198 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 8 5.0 COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(C)c(C)c3)nnn2c2ccc(Cl)cc12 nan
1375940 7556 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 5 1.0 COc1ccccc1NC=C1C(=O)N(C)C(=O)N(C)C1=O nan
CHEMBL1087646 7556 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 5 1.0 COc1ccccc1NC=C1C(=O)N(C)C(=O)N(C)C1=O nan
16019310 10759 11 None -47 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 8 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1 nan
CHEMBL1171436 10759 11 None -47 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 8 4.2 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccc(F)cc2)c2sccc23)cc1 nan
16019394 10865 8 None -37 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 8 4.6 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
CHEMBL1172405 10865 8 None -37 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 1 8 4.6 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 nan
16019397 10959 11 None -54 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 9 4.5 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1173286 10959 11 None -54 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 9 4.5 O=S(=O)(c1ccc(Cl)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
684664 15440 27 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 2.7 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccccc1 nan
CHEMBL1215029 15440 27 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 2 1 5 2.7 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccccc1 nan
34768 16401 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
CHEMBL1230732 16401 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
CHEMBL3392220 16401 59 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 5 10 -1.9 Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O nan
3733180 19679 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.7 O=C(Nc1nnc(-c2ccccc2F)s1)c1ccccc1F nan
CHEMBL1300733 19679 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.7 O=C(Nc1nnc(-c2ccccc2F)s1)c1ccccc1F nan
3815083 19718 30 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 1 5 2.5 N#Cc1cnn2c(N)c(-c3ccc(Cl)cc3)cnc12 nan
CHEMBL1301028 19718 30 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 1 5 2.5 N#Cc1cnn2c(N)c(-c3ccc(Cl)cc3)cnc12 nan
2219338 19871 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 2 3 5.0 O=C(Nc1cccc(C(F)(F)F)c1)c1cccnc1NCCc1ccccc1 nan
CHEMBL1302293 19871 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 6 2 3 5.0 O=C(Nc1cccc(C(F)(F)F)c1)c1cccnc1NCCc1ccccc1 nan
1217579 19877 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 6 4.5 N#Cc1ccc(-c2nc3cc(C#N)c(C#N)cc3nc2-c2ccccc2)cc1C#N nan
CHEMBL1302356 19877 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 0 6 4.5 N#Cc1ccc(-c2nc3cc(C#N)c(C#N)cc3nc2-c2ccccc2)cc1C#N nan
1244329 19951 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 3.6 COC(=O)c1c(-c2cccnc2)csc1NC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1302889 19951 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 3.6 COC(=O)c1c(-c2cccnc2)csc1NC(=O)c1ccc2c(c1)OCO2 nan
2740109 20088 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.5 N#Cc1c(N2CCOCC2)nsc1-c1ccc(C(F)(F)F)cc1 nan
CHEMBL1303994 20088 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.5 N#Cc1c(N2CCOCC2)nsc1-c1ccc(C(F)(F)F)cc1 nan
1462693 20358 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 8 2 7 2.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)C3CC3)s2)cc1 nan
CHEMBL1306151 20358 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 8 2 7 2.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)C3CC3)s2)cc1 nan
2158311 20360 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 5 5.1 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1C(F)(F)F nan
CHEMBL1306166 20360 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 5 5.1 O=C(CSc1ncnc2c1oc1ccccc12)Nc1ccccc1C(F)(F)F nan
940263 20395 40 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 1 2 2.8 Cc1cc(S)c2ccccc2n1 nan
CHEMBL1306515 20395 40 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 175 0 1 2 2.8 Cc1cc(S)c2ccccc2n1 nan
3678328 20692 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 4.0 O=C(COC(=O)c1cccc(Br)c1)Nc1cccc2c1C(=O)c1ccccc1C2=O nan
CHEMBL1308878 20692 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 4.0 O=C(COC(=O)c1cccc(Br)c1)Nc1cccc2c1C(=O)c1ccccc1C2=O nan
3942275 20829 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 7 4.6 CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 nan
CHEMBL1310132 20829 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 5 1 7 4.6 CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 nan
2744150 21284 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 7 4.3 Cc1nc(-c2nnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)n2C)cs1 nan
CHEMBL1313563 21284 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 7 4.3 Cc1nc(-c2nnc(SCC(=O)Nc3cc(Cl)cc(Cl)c3)n2C)cs1 nan
2997549 21355 8 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 8 2.9 Cc1ccc(S(=O)(=O)c2c(N)n(CCN3CCOCC3)c3nc4ccccc4nc23)cc1C nan
CHEMBL1314156 21355 8 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 5 1 8 2.9 Cc1ccc(S(=O)(=O)c2c(N)n(CCN3CCOCC3)c3nc4ccccc4nc23)cc1C nan
16009918 21366 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 7 1.5 Cc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1314250 21366 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 7 1.5 Cc1ccc(Cl)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
135458483 21380 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 1.7 Cc1ccn2c(=O)c(C(=O)NCCc3ccccc3)c(O)nc2c1 nan
CHEMBL1314355 21380 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 2 5 1.7 Cc1ccn2c(=O)c(C(=O)NCCc3ccccc3)c(O)nc2c1 nan
16024181 21402 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 4 3.9 Cc1cccc(N2C(=O)CS(=O)(=O)C23C(=O)N(Cc2c(F)cccc2Cl)c2ccccc23)c1 nan
CHEMBL1314689 21402 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 3 0 4 3.9 Cc1cccc(N2C(=O)CS(=O)(=O)C23C(=O)N(Cc2c(F)cccc2Cl)c2ccccc23)c1 nan
4913767 21413 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 0 7 3.2 COC(=O)Cc1c(C)c2ccc3c(c2oc1=O)CN(Cc1ccccc1OC)CO3 nan
CHEMBL1314916 21413 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 0 7 3.2 COC(=O)Cc1c(C)c2ccc3c(c2oc1=O)CN(Cc1ccccc1OC)CO3 nan
16027662 21424 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.5 O=C(Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1)c1ccc(F)cc1 nan
CHEMBL1315065 21424 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 7 3.5 O=C(Nc1cccc(C(=O)OCc2cc(=O)n3ccsc3n2)c1)c1ccc(F)cc1 nan
16021060 21457 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)cc1OC nan
CHEMBL1315440 21457 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)cc1OC nan
4524401 21469 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 1 8 4.0 COC(=O)c1ccccc1NC(=O)CSc1nc2ccsc2c(=O)n1CCC(C)C nan
CHEMBL1315570 21469 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 1 8 4.0 COC(=O)c1ccccc1NC(=O)CSc1nc2ccsc2c(=O)n1CCC(C)C nan
16020822 21471 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1315619 21471 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
16016226 21487 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 5.0 CC(=O)c1cccc(NC(=O)c2nc(-c3ccccc3)n(-c3cccc(Cl)c3)n2)c1 nan
CHEMBL1315816 21487 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 5.0 CC(=O)c1cccc(NC(=O)c2nc(-c3ccccc3)n(-c3cccc(Cl)c3)n2)c1 nan
16009840 21490 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 5.2 COc1ccccc1NC(=O)c1oc2ccccc2c1NC(=O)C1CCCCC1 nan
CHEMBL1315829 21490 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 2 4 5.2 COc1ccccc1NC(=O)c1oc2ccccc2c1NC(=O)C1CCCCC1 nan
16025104 21508 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 5 4.4 CC(=O)c1cccc(NC(=O)c2cnn(-c3cccc(C)c3)c2-n2cccc2)c1 nan
CHEMBL1316030 21508 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 1 5 4.4 CC(=O)c1cccc(NC(=O)c2cnn(-c3cccc(C)c3)c2-n2cccc2)c1 nan
1083262 21516 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 0 5 4.4 CCOC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1316119 21516 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 0 5 4.4 CCOC(=O)CSc1nc(-c2ccc(F)cc2)cc(C(F)(F)F)c1C#N nan
20940443 21535 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.5 CCCNC(=O)c1cc(-c2ccccc2)c(N2CCCCC2)s1 nan
CHEMBL1316420 21535 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 5 1 3 4.5 CCCNC(=O)c1cc(-c2ccccc2)c(N2CCCCC2)s1 nan
16022216 21580 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 4 4.7 CC(=O)c1ccc(NC(=O)CC(c2cccs2)N2Cc3ccccc3C2=O)cc1 nan
CHEMBL1317049 21580 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 4 4.7 CC(=O)c1ccc(NC(=O)CC(c2cccs2)N2Cc3ccccc3C2=O)cc1 nan
16027421 21587 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
CHEMBL1317129 21587 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1cccc(C(=O)Nc2cccc(C(=O)OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
2159322 21601 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 0 6 3.6 CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2c(C)ccc(OC)c21 nan
CHEMBL1317343 21601 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 0 6 3.6 CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2c(C)ccc(OC)c21 nan
16028188 21618 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 3 3.8 Cc1cccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)c1 nan
CHEMBL1317555 21618 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 3 2 3 3.8 Cc1cccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)c1 nan
16023037 21633 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 6 3.6 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(Cl)cc3)s2)cc1 nan
CHEMBL1317727 21633 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 6 3.6 Cc1ccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccc(Cl)cc3)s2)cc1 nan
2227086 21640 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 3 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cccc(Cl)c1 nan
CHEMBL1317881 21640 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 2 3 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cccc(Cl)c1 nan
16024891 21676 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 5 4.9 CSc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1318327 21676 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 5 1 5 4.9 CSc1ccc(CNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16025877 21703 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 8 2.9 CC(C)Oc1ccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)cc1 nan
CHEMBL1318545 21703 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 1 8 2.9 CC(C)Oc1ccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)cc1 nan
16445400 21726 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 2 1 5 2.8 Cc1nonc1NC(=O)c1oc2ccc(F)cc2c1C nan
CHEMBL1318745 21726 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 2 1 5 2.8 Cc1nonc1NC(=O)c1oc2ccc(F)cc2c1C nan
16022946 21821 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1319510 21821 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
16022818 21887 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(Cl)cc1NC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)CC1 nan
CHEMBL1320089 21887 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(Cl)cc1NC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccccc4)nc23)CC1 nan
4183241 21892 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccc(F)cc3)n2)cc1 nan
CHEMBL1320138 21892 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccc(F)cc3)n2)cc1 nan
3167480 21902 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 5.1 Cc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
CHEMBL1320193 21902 6 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 5.1 Cc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
16023651 21905 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 3 5 3.6 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(C)c2)N3)cc1 nan
CHEMBL1320214 21905 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 7 3 5 3.6 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(C)c2)N3)cc1 nan
16009865 21934 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 1 6 3.6 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1320479 21934 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 1 6 3.6 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
3613580 22069 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 1 5 3.7 CNc1nc(-c2ccccc2)nc(-c2ccc(OC)cc2)c1C#N nan
CHEMBL1321693 22069 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 1 5 3.7 CNc1nc(-c2ccccc2)nc(-c2ccc(OC)cc2)c1C#N nan
16026062 22234 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.6 Cc1cccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1C nan
CHEMBL1323207 22234 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 1 7 2.6 Cc1cccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1C nan
720155 22264 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 2 2 4.8 Cc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(C)c3)c2)c1 nan
CHEMBL1323476 22264 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 2 2 4.8 Cc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(C)c3)c2)c1 nan
866639 22287 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 6 2.4 Cc1cccn2c(=O)c3cc(C(=O)N4COCC4(C)C)sc3nc12 nan
CHEMBL1323660 22287 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 1 0 6 2.4 Cc1cccn2c(=O)c3cc(C(=O)N4COCC4(C)C)sc3nc12 nan
7597258 22412 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 4 3.7 Cc1ccc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c(C)c1 nan
CHEMBL1324652 22412 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 4 3.7 Cc1ccc(-c2nnc(NC(=O)Cc3ccc(F)cc3)o2)c(C)c1 nan
20903561 22469 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 2 5 3.1 O=C(Nc1ccc(F)cc1)C1CCCN(S(=O)(=O)c2ccc3nc(O)ccc3c2)C1 nan
CHEMBL1325113 22469 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 2 5 3.1 O=C(Nc1ccc(F)cc1)C1CCCN(S(=O)(=O)c2ccc3nc(O)ccc3c2)C1 nan
1239703 22486 8 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.0 CCc1nnc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)s1 nan
CHEMBL1325279 22486 8 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 7 3.0 CCc1nnc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)s1 nan
4053254 22582 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 2 5 3.1 COc1ccc(NC(=O)CCn2c(=S)[nH]c3ccccc3c2=O)cc1 nan
CHEMBL1326345 22582 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 2 5 3.1 COc1ccc(NC(=O)CCn2c(=S)[nH]c3ccccc3c2=O)cc1 nan
2742890 22668 5 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 2 2 4.3 COc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
CHEMBL1327081 22668 5 None -7 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 3 2 2 4.3 COc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
16030465 22733 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)N1CCCCC1 nan
CHEMBL1327646 22733 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 0 4 4.3 O=C(CSc1nc2ccccc2nc1Cc1ccccc1)N1CCCCC1 nan
2330460 22792 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 7 5.0 Cc1nn(-c2ccccc2Cl)c2sc(C(=O)Nc3nnc(C4CC4)s3)cc12 nan
CHEMBL1328005 22792 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 7 5.0 Cc1nn(-c2ccccc2Cl)c2sc(C(=O)Nc3nnc(C4CC4)s3)cc12 nan
1048410 23235 8 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 4 5.6 COc1cc(NC(=O)c2ccc(-c3ccc(Br)cc3)o2)ccc1NC(=O)C(C)C nan
CHEMBL1331632 23235 8 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 2 4 5.6 COc1cc(NC(=O)c2ccc(-c3ccc(Br)cc3)o2)ccc1NC(=O)C(C)C nan
1088560 23244 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 1 3 4.1 CC(=O)c1cn(CC(=O)Nc2ccc(C)c(C)c2)c2ccccc12 nan
CHEMBL1331684 23244 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 1 3 4.1 CC(=O)c1cn(CC(=O)Nc2ccc(C)c(C)c2)c2ccccc12 nan
16022830 23346 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)c(Cl)c1 nan
CHEMBL1332482 23346 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 1 6 5.2 Cc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)c(Cl)c1 nan
4443607 23550 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 3.3 COc1cc2[nH]c(=S)n(Cc3ccc(F)cc3)c(=O)c2cc1OC nan
CHEMBL1334074 23550 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 1 5 3.3 COc1cc2[nH]c(=S)n(Cc3ccc(F)cc3)c(=O)c2cc1OC nan
3245441 23594 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 3.1 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc1c2c(nc3c1CCC3)CCC2 nan
CHEMBL1334367 23594 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 3.1 O=C(CCCN1C(=O)c2ccccc2C1=O)Nc1c2c(nc3c1CCC3)CCC2 nan
16009378 23671 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 5 3.8 Cc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c(C)c1 nan
CHEMBL1335076 23671 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 3 0 5 3.8 Cc1ccc(OCc2cc(=O)n3c4c(sc3n2)CCCC4)c(C)c1 nan
135454500 23918 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.6 Cc1cc(-n2c(SCC(=O)Nc3ccc(F)c(F)c3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1337074 23918 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.6 Cc1cc(-n2c(SCC(=O)Nc3ccc(F)c(F)c3)nc3nnc(C)c-3c2N)ccc1Cl nan
16023881 24004 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 2 4.2 O=C(Nc1ccc(F)cc1F)c1cc2ccc3cccnc3c2[nH]1 nan
CHEMBL1337846 24004 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 2 4.2 O=C(Nc1ccc(F)cc1F)c1cc2ccc3cccnc3c2[nH]1 nan
3458131 24170 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
CHEMBL1339257 24170 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
3677224 24198 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 6 3.3 O=C(NCCc1ccccc1)c1cc(-c2ccncc2)nc2ccc(S(=O)(=O)N3CCOCC3)cc12 nan
CHEMBL1339543 24198 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 6 3.3 O=C(NCCc1ccccc1)c1cc(-c2ccncc2)nc2ccc(S(=O)(=O)N3CCOCC3)cc12 nan
4625935 24257 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccc(F)cc2)nc1-c1ccccc1 nan
CHEMBL1340080 24257 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccc(F)cc2)nc1-c1ccccc1 nan
1873236 24532 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 7 2.6 COC(=O)c1ccc2c(=O)n(Cc3ccc4c(c3)OCO4)c(=S)[nH]c2c1 nan
CHEMBL1342433 24532 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 7 2.6 COC(=O)c1ccc2c(=O)n(Cc3ccc4c(c3)OCO4)c(=S)[nH]c2c1 nan
1302080 24592 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 2 4 2.8 O=C(CCc1ccccc1)NC(=S)Nc1ccc2c(c1)C(=O)OC2 nan
CHEMBL1342849 24592 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 2 4 2.8 O=C(CCc1ccccc1)NC(=S)Nc1ccc2c(c1)C(=O)OC2 nan
3185654 24637 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 3.3 COc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCC1)c1ccc(N(C)C)cc1 nan
CHEMBL1343261 24637 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 3.3 COc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCC1)c1ccc(N(C)C)cc1 nan
1164441 24688 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 7 4.8 COc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
CHEMBL1343720 24688 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 1 7 4.8 COc1ccc2nc(SCC(=O)Nc3ccc4sc(C)nc4c3)c(C#N)cc2c1 nan
653965 24713 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 4 3.8 Cc1cc(C)c2nc(SCC(=O)N3CCCCC3)c(C#N)cc2c1 nan
CHEMBL1343941 24713 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 3 0 4 3.8 Cc1cc(C)c2nc(SCC(=O)N3CCCCC3)c(C#N)cc2c1 nan
5068572 25179 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 6 3.1 COc1ccc(Cn2c(=S)[nH]c3cc(OC)c(OC)cc3c2=O)cc1 nan
CHEMBL1347842 25179 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 6 3.1 COc1ccc(Cn2c(=S)[nH]c3cc(OC)c(OC)cc3c2=O)cc1 nan
2992621 25224 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 4 3.0 COc1cccc2cc(C(=O)NCc3ccc(C)cc3)c(=O)oc12 nan
CHEMBL1348238 25224 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 4 3.0 COc1cccc2cc(C(=O)NCc3ccc(C)cc3)c(=O)oc12 nan
2785932 25300 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 0 0 5 1.4 Cn1c(=O)c2cc3ccc(Cl)cc3nc2n(C)c1=O nan
CHEMBL1348983 25300 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 275 0 0 5 1.4 Cn1c(=O)c2cc3ccc(Cl)cc3nc2n(C)c1=O nan
20929691 25325 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 3.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccco3)c2n1 nan
CHEMBL1349170 25325 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 6 3.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccco3)c2n1 nan
1261778 25557 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 1 3 5.6 Cc1cccc2c(C(=O)Nc3ccc(Br)cc3)cc(-c3ccccn3)nc12 nan
CHEMBL1351124 25557 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 1 3 5.6 Cc1cccc2c(C(=O)Nc3ccc(Br)cc3)cc(-c3ccccn3)nc12 nan
2309203 25560 7 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 4 4.3 O=C(NCCCCNC(=O)c1ccc(Br)s1)c1ccc(Br)s1 nan
CHEMBL1351160 25560 7 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 4 4.3 O=C(NCCCCNC(=O)c1ccc(Br)s1)c1ccc(Br)s1 nan
1945599 25693 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 6 3.7 COc1cc(C(=O)NC(=S)Nc2cccc3nc(C)ccc23)cc(OC)c1OC nan
CHEMBL1352289 25693 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 2 6 3.7 COc1cc(C(=O)NC(=S)Nc2cccc3nc(C)ccc23)cc(OC)c1OC nan
2345662 25802 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 6 2.8 COc1ccc(-c2nnc(NC(=O)C(C)C)s2)c(OC)c1 nan
CHEMBL1353144 25802 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 5 1 6 2.8 COc1ccc(-c2nnc(NC(=O)C(C)C)s2)c(OC)c1 nan
2588947 25838 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.2 COc1ccc2c(-c3ccccc3)cc(SCC(=O)NC(N)=O)nc2c1 nan
CHEMBL1353338 25838 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 2 5 3.2 COc1ccc2c(-c3ccccc3)cc(SCC(=O)NC(N)=O)nc2c1 nan
16024589 25972 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3Cl)c2n1 nan
CHEMBL1354308 25972 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 6 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3Cl)c2n1 nan
24981187 25980 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 0 7 2.0 CCOC(=O)C1CCN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)CC1 nan
CHEMBL1354340 25980 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 0 7 2.0 CCOC(=O)C1CCN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3ccc(C)c(C)c3)CC2)CC1 nan
16015624 26010 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 6 5.8 Cc1ccccc1OCC(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
CHEMBL1354759 26010 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 6 5.8 Cc1ccccc1OCC(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
16022729 26068 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 2.5 Cc1noc(Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)ccc3C)c2=O)n1 nan
CHEMBL1355436 26068 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 1 8 2.5 Cc1noc(Cn2c(=O)c3ccccc3n(CC(=O)Nc3cc(Cl)ccc3C)c2=O)n1 nan
15989639 26071 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.4 COc1ccc(CCn2c(=O)c3ccccc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
CHEMBL1355514 26071 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 8 1 7 3.4 COc1ccc(CCn2c(=O)c3ccccc3n(CC(=O)Nc3cccc(C)c3)c2=O)cc1OC nan
16023098 26076 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 5 4.1 Cc1nnc2c3ccccc3nc(Nc3ccc(F)cc3Cl)n12 nan
CHEMBL1355617 26076 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 1 5 4.1 Cc1nnc2c3ccccc3nc(Nc3ccc(F)cc3Cl)n12 nan
2150160 26077 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 6 4.2 COCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
CHEMBL1355622 26077 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 6 4.2 COCCCNc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 nan
135546934 26082 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 3 3 7 4.3 Cc1cccc(NC(=O)c2sc3nc(-c4cc5ccc(O)cc5oc4=O)[nH]c(=O)c3c2C)c1 nan
CHEMBL1355684 26082 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 3 3 7 4.3 Cc1cccc(NC(=O)c2sc3nc(-c4cc5ccc(O)cc5oc4=O)[nH]c(=O)c3c2C)c1 nan
135419178 26103 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 5 4.8 CC(=O)Nc1ccc(/C=C/c2nc(-c3ccccc3O)n(-c3ccccc3)n2)cc1 nan
CHEMBL1355898 26103 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 5 4.8 CC(=O)Nc1ccc(/C=C/c2nc(-c3ccccc3O)n(-c3ccccc3)n2)cc1 nan
16017045 26148 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 0 6 4.8 CCC(C(=O)N1CCN(c2cccc(C)c2C)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1356499 26148 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 4 0 6 4.8 CCC(C(=O)N1CCN(c2cccc(C)c2C)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
15990110 26150 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 5 5.3 Cc1ccc(C)c(N2CCN(C(c3ccccc3)c3nnc(-c4ccccc4)o3)CC2)c1 nan
CHEMBL1356570 26150 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 0 5 5.3 Cc1ccc(C)c(N2CCN(C(c3ccccc3)c3nnc(-c4ccccc4)o3)CC2)c1 nan
5886984 26155 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 6.8 COc1c(Cl)cc(Cl)cc1/C=C(\C#N)c1nc(-c2ccc(Cl)cc2)cs1 nan
CHEMBL1356614 26155 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 4 0 4 6.8 COc1c(Cl)cc(Cl)cc1/C=C(\C#N)c1nc(-c2ccc(Cl)cc2)cs1 nan
16018240 26177 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 5.2 Cc1c(C(=O)NCc2ccc(N(C)C)cc2)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
CHEMBL1356884 26177 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 5.2 Cc1c(C(=O)NCc2ccc(N(C)C)cc2)oc2c1-c1nn(Cc3cccc(Cl)c3)cc1CC2 nan
2219490 26187 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 4 5.1 O=C(Cn1cc(C(=O)c2ccco2)c2ccccc21)Nc1ccccc1C(F)(F)F nan
CHEMBL1357026 26187 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 4 5.1 O=C(Cn1cc(C(=O)c2ccco2)c2ccccc21)Nc1ccccc1C(F)(F)F nan
16007510 26212 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 1 4 5.6 CCOc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
CHEMBL1357328 26212 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 7 1 4 5.6 CCOc1ccc(CNC(=O)CSc2c3c(nc4ccc(Cl)cc24)CCCC3)cc1 nan
16010573 26213 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 8 1 7 2.6 CCOc1ccccc1NC(=O)Cn1c(=O)n(CCC(C)C)c(=O)c2cccnc21 nan
CHEMBL1357333 26213 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 8 1 7 2.6 CCOc1ccccc1NC(=O)Cn1c(=O)n(CCC(C)C)c(=O)c2cccnc21 nan
7533493 26219 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 6 4.1 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(F)ccc3F)o2)cc1 nan
CHEMBL1357469 26219 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 6 4.1 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(F)ccc3F)o2)cc1 nan
16030313 26243 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
CHEMBL1357868 26243 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
7244606 26246 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 0 7 2.9 C#CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OC)c(OC)cc21 nan
CHEMBL1357945 26246 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 0 7 2.9 C#CCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(OC)c(OC)cc21 nan
16018859 26250 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.1 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1C(F)(F)F nan
CHEMBL1357984 26250 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.1 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1C(F)(F)F nan
16009434 26254 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 7 3.4 O=C(COc1ccccc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1358022 26254 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 7 3.4 O=C(COc1ccccc1)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
15987969 26330 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 4 4.1 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3cccc(CC)c3)c21 nan
CHEMBL1358851 26330 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 7 1 4 4.1 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3cccc(CC)c3)c21 nan
3799752 26331 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 2.4 COc1ccc(OC)c(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)c1 nan
CHEMBL1358861 26331 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 2 6 2.4 COc1ccc(OC)c(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)c1 nan
7210861 26408 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 5 3.6 CCn1c(SCC(=O)Nc2ccccc2)nc2c([nH]c3ccccc32)c1=O nan
CHEMBL1359450 26408 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 5 3.6 CCn1c(SCC(=O)Nc2ccccc2)nc2c([nH]c3ccccc32)c1=O nan
1818953 26567 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 6 5.7 C=C(C)Cn1c(SCC(=O)c2ccc(Br)cc2)nc2sc3c(c2c1=O)CCCC3 nan
CHEMBL1360901 26567 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 0 6 5.7 C=C(C)Cn1c(SCC(=O)c2ccc(Br)cc2)nc2sc3c(c2c1=O)CCCC3 nan
16022921 26629 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
CHEMBL1361507 26629 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 4.7 CCOc1ccccc1CNC(=O)C1CCN(c2nnc(C)c3c(C)n(-c4ccc(C)cc4)nc23)CC1 nan
4329717 26642 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 2 3 4.2 CC(NC(=O)c1cc(O)nc2ccc(Br)cc12)c1ccccc1 nan
CHEMBL1361599 26642 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 2 3 4.2 CC(NC(=O)c1cc(O)nc2ccc(Br)cc12)c1ccccc1 nan
3475073 26680 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 2 5.4 Cc1cc2ccccc2n1CCNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
CHEMBL1361903 26680 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 2 5.4 Cc1cc2ccccc2n1CCNC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 nan
16022126 26709 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 4.5 COc1cc(OC)c(NC(=O)c2c(N3CCCC3=O)c3cc(C)ccc3n2C)cc1Cl nan
CHEMBL1362140 26709 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 1 5 4.5 COc1cc(OC)c(NC(=O)c2c(N3CCCC3=O)c3cc(C)ccc3n2C)cc1Cl nan
1984900 26734 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 8 1 7 5.0 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3cccs3)cc2)cc1 nan
CHEMBL1362375 26734 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 8 1 7 5.0 CCOc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3cccs3)cc2)cc1 nan
6471827 26765 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 9 2.4 Cc1nnc(NC(=O)C(C)Sc2nnc(-c3ccco3)n2C)s1 nan
CHEMBL1362583 26765 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 5 1 9 2.4 Cc1nnc(NC(=O)C(C)Sc2nnc(-c3ccco3)n2C)s1 nan
7693885 26778 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 4 1 4 3.9 COc1ccc(C(=O)Nc2cc(-c3ccc(C)cc3)no2)cc1 nan
CHEMBL1362677 26778 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 4 1 4 3.9 COc1ccc(C(=O)Nc2cc(-c3ccc(C)cc3)no2)cc1 nan
16019393 26789 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 4.0 CCCCNc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12 nan
CHEMBL1362800 26789 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 4.0 CCCCNc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12 nan
22334175 26807 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 10 2 10 2.8 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cc(OC)c(OC)c(OC)c3)c3ccccc3c2=O)cc1OC nan
CHEMBL1362992 26807 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 548 10 2 10 2.8 COc1ccc(-n2nc(C(=O)NCC(=O)Nc3cc(OC)c(OC)c(OC)c3)c3ccccc3c2=O)cc1OC nan
645413 26819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 3.4 Cc1cc(C(F)F)n2nc(C(=O)Nc3ccccc3Br)nc2n1 nan
CHEMBL1363101 26819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 3 1 5 3.4 Cc1cc(C(F)F)n2nc(C(=O)Nc3ccccc3Br)nc2n1 nan
16024545 26829 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)c1 nan
CHEMBL1363144 26829 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccc(Cl)cc3)c(=O)c3ccc(C)nc32)c1 nan
4447999 26865 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 2 6 4.6 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCC(=O)NC2CCCCC2)cc1C nan
CHEMBL1363483 26865 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 492 8 2 6 4.6 Cc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2CCC(=O)NC2CCCCC2)cc1C nan
16030946 26915 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 4.1 COc1ccc(NC(=O)CSc2ccc3nc(-c4ccccc4)cn3n2)cc1OC nan
CHEMBL1363950 26915 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 7 1 7 4.1 COc1ccc(NC(=O)CSc2ccc3nc(-c4ccccc4)cn3n2)cc1OC nan
1960168 26973 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 2 0 5 4.4 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccc(F)cc2)cc1 nan
CHEMBL1364491 26973 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 2 0 5 4.4 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccc(F)cc2)cc1 nan
1258567 27166 17 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.5 COc1ccc(-c2cc(-c3ccccc3)nc(SCC(=O)Nc3nccs3)c2C#N)cc1 nan
CHEMBL1366086 27166 17 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 1 7 5.5 COc1ccc(-c2cc(-c3ccccc3)nc(SCC(=O)Nc3nccs3)c2C#N)cc1 nan
5726342 27200 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 3.8 CN1C(=O)C(O)=C(C(=O)c2ccc(Br)cc2)C1c1ccc(F)cc1 nan
CHEMBL1366379 27200 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 3 1 3 3.8 CN1C(=O)C(O)=C(C(=O)c2ccc(Br)cc2)C1c1ccc(F)cc1 nan
16015810 27214 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cccc(-c3nc4ccccc4s3)c2C)cc1 nan
CHEMBL1366460 27214 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 5 5.3 COc1ccc(OCC(=O)Nc2cccc(-c3nc4ccccc4s3)c2C)cc1 nan
5204153 27235 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 1.3 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3ccc4c(c3)C(=O)NC4=O)cc2)CC1 nan
CHEMBL1366674 27235 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 1.3 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3ccc4c(c3)C(=O)NC4=O)cc2)CC1 nan
16015685 27273 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 5.5 Cc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc54)sc3c2)cc1 nan
CHEMBL1367053 27273 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 5.5 Cc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCc5ccccc54)sc3c2)cc1 nan
561651 27386 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 0 3 4.6 c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1 nan
CHEMBL1367925 27386 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 0 3 4.6 c1ccc(C2=NN(c3ccccc3)C(c3ccco3)C2)cc1 nan
16022119 27615 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.9 COc1ccc2c(c1)c1c(c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)n1Cc1ccc(F)cc1)n2C nan
CHEMBL1369667 27615 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.9 COc1ccc2c(c1)c1c(c(=O)n(-c3ccc(OC)c(OC)c3)c(=O)n1Cc1ccc(F)cc1)n2C nan
16024643 27645 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 5 3.9 CCc1ccc(C(=O)c2cn(CC(=O)NCCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1369852 27645 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 5 3.9 CCc1ccc(C(=O)c2cn(CC(=O)NCCc3ccccc3)c3nc(C)ccc3c2=O)cc1 nan
16018703 27690 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 0 6 3.4 Cc1ccc(Cl)cc1N1CCN(C(=O)CCn2c(=O)c3cccn3c3cccnc32)CC1 nan
CHEMBL1370112 27690 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 4 0 6 3.4 Cc1ccc(Cl)cc1N1CCN(C(=O)CCn2c(=O)c3cccn3c3cccnc32)CC1 nan
16017844 27767 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 6 1.6 COc1cccc(-n2ccn(CC(=O)NCc3ccc(C)cc3)c(=O)c2=O)c1 nan
CHEMBL1370655 27767 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 6 1 6 1.6 COc1cccc(-n2ccn(CC(=O)NCc3ccc(C)cc3)c(=O)c2=O)c1 nan
2053979 27782 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 4.0 CCN(C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)C1CCCCC1 nan
CHEMBL1370734 27782 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 4.0 CCN(C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1)C1CCCCC1 nan
2999996 27809 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 3 0 9 2.9 O=C(OCc1cc(=O)n2c(n1)sc1ccccc12)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
CHEMBL1370976 27809 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 3 0 9 2.9 O=C(OCc1cc(=O)n2c(n1)sc1ccccc12)c1ccc2c(=O)n3c(nc2c1)CCC3 nan
2212806 27863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 4 5.1 Cc1cccc(NC(=O)c2cc(NC(=O)c3ccco3)ccc2N2CCCCC2)c1 nan
CHEMBL1371405 27863 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 2 4 5.1 Cc1cccc(NC(=O)c2cc(NC(=O)c3ccco3)ccc2N2CCCCC2)c1 nan
4069120 27881 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.7 COc1ccc(OC)c(NC(=O)c2oc(=O)c3ccccc3c2-c2ccccc2)c1 nan
CHEMBL1371548 27881 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.7 COc1ccc(OC)c(NC(=O)c2oc(=O)c3ccccc3c2-c2ccccc2)c1 nan
862401 27894 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 3.7 COc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
CHEMBL1371650 27894 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 3.7 COc1ccc2nc(SCC(=O)NC3CCCC3)c(C)cc2c1 nan
941550 27898 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 6 3.4 COc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
CHEMBL1371690 27898 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 6 3.4 COc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
648869 28019 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 5 3.9 CCOc1ccc2cc(C#N)c(SCC(=O)N3CCC(C)CC3)nc2c1 nan
CHEMBL1372547 28019 5 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 5 3.9 CCOc1ccc2cc(C#N)c(SCC(=O)N3CCC(C)CC3)nc2c1 nan
664361 28066 12 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1nc(SCC(=O)Nc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1372818 28066 12 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1nc(SCC(=O)Nc2ccccc2)c2oc3ccccc3c2n1 nan
2404728 28196 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.4 O=C(COC(=O)c1ccc(Cl)cc1O)NC(=O)C1CCCCC1 nan
CHEMBL1373640 28196 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 2 5 2.4 O=C(COC(=O)c1ccc(Cl)cc1O)NC(=O)C1CCCCC1 nan
711468 28233 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 1 1 3 3.3 Cc1cc(-c2cccc(Br)c2)c(C#N)c(N)n1 nan
CHEMBL1373906 28233 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 1 1 3 3.3 Cc1cc(-c2cccc(Br)c2)c(C#N)c(N)n1 nan
660358 28275 21 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 8 4.8 CCOC(=O)c1sc(NC(=O)CSc2nc3c(cc2C#N)CCCCCC3)c(C#N)c1C nan
CHEMBL1374224 28275 21 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 6 1 8 4.8 CCOC(=O)c1sc(NC(=O)CSc2nc3c(cc2C#N)CCCCCC3)c(C#N)c1C nan
848636 28320 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 6 5.1 Cc1sc2ncnc(Sc3nc4ccccc4s3)c2c1C nan
CHEMBL1374559 28320 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 6 5.1 Cc1sc2ncnc(Sc3nc4ccccc4s3)c2c1C nan
22330687 28343 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 8 4.3 COc1ccc(C)cc1NC(=O)c1sc2ncnc(N3CCN(c4ccccn4)CC3)c2c1C nan
CHEMBL1374703 28343 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 8 4.3 COc1ccc(C)cc1NC(=O)c1sc2ncnc(N3CCN(c4ccccn4)CC3)c2c1C nan
16421351 28370 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
5513687 28370 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
CHEMBL1374848 28370 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 6 3.8 COc1ccc(-c2cc3ccc(O)c(CN4CCCC4)c3oc2=O)cc1OC nan
2113664 28497 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 0 8 4.2 CCc1cc2c(SCC(=O)C(C#N)=C3N(C)c4ccccc4N3C)ncnc2s1 nan
CHEMBL1375768 28497 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 0 8 4.2 CCc1cc2c(SCC(=O)C(C#N)=C3N(C)c4ccccc4N3C)ncnc2s1 nan
1049792 28548 24 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 0 5 5.0 COc1ccc(-c2cc(-c3ccc(OC)cc3)c(C#N)c(SC)n2)cc1 nan
CHEMBL1376368 28548 24 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 0 5 5.0 COc1ccc(-c2cc(-c3ccc(OC)cc3)c(C#N)c(SC)n2)cc1 nan
3141909 28553 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 2 0 4 3.0 Cc1cccc2cc(C#N)c(SCC#N)nc12 nan
CHEMBL1376381 28553 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 239 2 0 4 3.0 Cc1cccc2cc(C#N)c(SCC#N)nc12 nan
1086373 28606 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 1 6 3.6 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCc3ccco3)n2)c1 nan
CHEMBL1376846 28606 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 7 1 6 3.6 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCc3ccco3)n2)c1 nan
16024493 28695 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 5 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1377756 28695 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 5 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
16018882 28701 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 1 5 4.2 CCOc1ccc(N(CC)S(=O)(=O)N2CCCC(C(=O)Nc3ccc(OC)c(Cl)c3)C2)cc1 nan
CHEMBL1377806 28701 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 1 5 4.2 CCOc1ccc(N(CC)S(=O)(=O)N2CCCC(C(=O)Nc3ccc(OC)c(Cl)c3)C2)cc1 nan
2426511 28769 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 0 0 4 2.7 Cc1cc(=O)n2c(sc3ccccc32)c1C#N nan
CHEMBL1378393 28769 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 0 0 4 2.7 Cc1cc(=O)n2c(sc3ccccc32)c1C#N nan
2060585 28784 68 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 1 2 1.4 O=C(c1ccccc1Cl)N1CCNCC1 nan
CHEMBL1378602 28784 68 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 224 1 1 2 1.4 O=C(c1ccccc1Cl)N1CCNCC1 nan
54680441 28858 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 3 4 2.6 O=C(NCc1ccccc1)c1c(O)nc2ccccc2c1O nan
CHEMBL1379243 28858 20 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 3 3 4 2.6 O=C(NCc1ccccc1)c1c(O)nc2ccccc2c1O nan
7502810 28916 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 3.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc(Br)cc3)nn2)no1 nan
CHEMBL1379696 28916 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 3.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc(Br)cc3)nn2)no1 nan
663350 28976 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 9 2.9 COc1cc(OC)c(-c2nn3c(-c4cccnc4)nnc3s2)cc1OC nan
CHEMBL1380292 28976 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 0 9 2.9 COc1cc(OC)c(-c2nn3c(-c4cccnc4)nnc3s2)cc1OC nan
551775 29070 13 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 0 5 4.0 CCN(CC)C(=O)CSc1nc(C)cc(-c2cccs2)c1C#N nan
CHEMBL1380940 29070 13 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 6 0 5 4.0 CCN(CC)C(=O)CSc1nc(C)cc(-c2cccs2)c1C#N nan
6470016 29206 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 2 2 3.4 CC1=C(C)CC(C(=O)NCc2cccc(Cl)c2)C(C(=O)O)C1 nan
CHEMBL1382205 29206 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 2 2 3.4 CC1=C(C)CC(C(=O)NCc2cccc(Cl)c2)C(C(=O)O)C1 nan
4908628 29215 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 4 3.4 Cc1ccc(S(=O)(=O)N(C)Cc2cc3cc(C)ccc3nc2O)cc1 nan
CHEMBL1382276 29215 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 4 3.4 Cc1ccc(S(=O)(=O)N(C)Cc2cc3cc(C)ccc3nc2O)cc1 nan
1450725 29218 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 0 7 1.8 N#Cc1cc2cc3c(cc2nc1SCC(=O)N1CCOCC1)OCO3 nan
CHEMBL1382288 29218 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 0 7 1.8 N#Cc1cc2cc3c(cc2nc1SCC(=O)N1CCOCC1)OCO3 nan
5155717 29375 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 5 2.1 NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 nan
CHEMBL1383680 29375 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 2 5 2.1 NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 nan
1271521 29569 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 O=C(Nc1ccc(-c2noc(-c3ccccc3F)n2)cc1)c1cccs1 nan
CHEMBL1385411 29569 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 5 4.9 O=C(Nc1ccc(-c2noc(-c3ccccc3F)n2)cc1)c1cccs1 nan
1604314 29707 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 6 3.6 CCOC(=O)C1=C(c2ccccc2)O/C(=C(/C(=O)OC)C(F)(F)F)S1 nan
CHEMBL1386476 29707 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 6 3.6 CCOC(=O)C1=C(c2ccccc2)O/C(=C(/C(=O)OC)C(F)(F)F)S1 nan
2815677 29723 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 0 6 1.5 CCOC(=O)c1cn2nc(N3CCCC3)ccc2n1 nan
CHEMBL1386622 29723 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 3 0 6 1.5 CCOC(=O)c1cn2nc(N3CCCC3)ccc2n1 nan
979520 29846 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 4 4.5 COc1cc(CNCc2ccccc2Cl)ccc1OCC(=O)NC1CCCCC1 nan
CHEMBL1387627 29846 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 9 2 4 4.5 COc1cc(CNCc2ccccc2Cl)ccc1OCC(=O)NC1CCCCC1 nan
855469 29882 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 3.4 Cc1cc(NC(=O)CSc2nc3c(C)cccc3cc2C#N)no1 nan
CHEMBL1387916 29882 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 6 3.4 Cc1cc(NC(=O)CSc2nc3c(C)cccc3cc2C#N)no1 nan
1026561 29893 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 2 3 4.5 CCOc1ccc(Br)cc1C(=O)Nc1ccc(C(=O)NCC(C)C)cc1 nan
CHEMBL1388002 29893 11 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 2 3 4.5 CCOc1ccc(Br)cc1C(=O)Nc1ccc(C(=O)NCC(C)C)cc1 nan
2372910 29938 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 0 5 3.3 c1ccc(-c2cc(-c3nnco3)c3ccccc3n2)nc1 nan
CHEMBL1388328 29938 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 2 0 5 3.3 c1ccc(-c2cc(-c3nnco3)c3ccccc3n2)nc1 nan
4909035 30178 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 5 4.0 Cc1cccc(-c2nc3c(c(SCC(=O)N4CCCC4)n2)COC(C)(C)C3)c1 nan
CHEMBL1390262 30178 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 5 4.0 Cc1cccc(-c2nc3c(c(SCC(=O)N4CCCC4)n2)COC(C)(C)C3)c1 nan
20969169 30205 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 4.1 COc1ccc(Cl)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
CHEMBL1390480 30205 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 4 1 7 4.1 COc1ccc(Cl)cc1NC(=O)c1sc2nc(C)nc(N3CCOCC3)c2c1C nan
4688970 30212 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 1 6 4.2 Cc1nc(N2CCOCC2)c2c(C)c(C(=O)Nc3ccc(F)cc3Cl)sc2n1 nan
CHEMBL1390558 30212 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 3 1 6 4.2 Cc1nc(N2CCOCC2)c2c(C)c(C(=O)Nc3ccc(F)cc3Cl)sc2n1 nan
6621188 30216 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 2 4 2.3 CCc1ccc(NC(=O)CNC(=O)Cn2ccc3ccccc3c2=O)cc1 nan
CHEMBL1390571 30216 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 6 2 4 2.3 CCc1ccc(NC(=O)CNC(=O)Cn2ccc3ccccc3c2=O)cc1 nan
24687564 30353 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 7 4.0 CCOC(=O)c1c(NC(=O)COc2ccccc2C#N)sc2c1CC(C)(C)NC2(C)C nan
CHEMBL1391818 30353 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 7 4.0 CCOC(=O)c1c(NC(=O)COc2ccccc2C#N)sc2c1CC(C)(C)NC2(C)C nan
8030390 30450 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 3.1 Cc1c(C)c2ccc(OCC(=O)Nc3ccccn3)c(C)c2oc1=O nan
CHEMBL1392611 30450 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 1 5 3.1 Cc1c(C)c2ccc(OCC(=O)Nc3ccccn3)c(C)c2oc1=O nan
649622 30521 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
CHEMBL1393221 30521 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.5 CCOC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
16024685 30619 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 5 5.2 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)Nc3ccccc3C(F)(F)F)c2n1 nan
CHEMBL1394039 30619 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 5 1 5 5.2 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)Nc3ccccc3C(F)(F)F)c2n1 nan
3844740 30621 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 3 7 3.8 COc1ccc(C2C=C(c3ccc(Cl)cc3)Nc3nc(NC(=O)CCC(=O)O)nn32)cc1 nan
CHEMBL1394052 30621 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 3 7 3.8 COc1ccc(C2C=C(c3ccc(Cl)cc3)Nc3nc(NC(=O)CCC(=O)O)nn32)cc1 nan
16024945 30633 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)nnn2C1CCCC1 nan
CHEMBL1394171 30633 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2c(c1)nnn2C1CCCC1 nan
2136700 30640 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 3.8 Cc1ccccc1NC(=O)Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21 nan
CHEMBL1394236 30640 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 3.8 Cc1ccccc1NC(=O)Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2ccccc21 nan
16017140 30678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 5 5.0 Cc1ccc(C)c(NC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
CHEMBL1394852 30678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 5 5.0 Cc1ccc(C)c(NC(=O)CCCn2nc(C)c3sc4ccccc4c3c2=O)c1 nan
16022416 30679 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 7 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
CHEMBL1394859 30679 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 7 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCCc4ccccc4)cc3nc2s1 nan
16030605 30686 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCCc2ccccc21 nan
CHEMBL1394911 30686 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCCc2ccccc21 nan
16034772 30722 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 6 4.6 Cc1nn(CCCC(=O)Nc2cccc(C(F)(F)F)c2)c(=O)c2nn(-c3ccccc3)c(C)c12 nan
CHEMBL1395185 30722 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 6 4.6 Cc1nn(CCCC(=O)Nc2cccc(C(F)(F)F)c2)c(=O)c2nn(-c3ccccc3)c(C)c12 nan
2007143 30726 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 1.9 CCOC(=O)CNC(=O)c1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 nan
CHEMBL1395237 30726 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 1.9 CCOC(=O)CNC(=O)c1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 nan
16019606 30727 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccccc2Cl)c2sccc23)cc1 nan
CHEMBL1395245 30727 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2ccccc2Cl)c2sccc23)cc1 nan
16018799 30729 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 5 3.2 CCc1cccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1395272 30729 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 1 5 3.2 CCc1cccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)c1 nan
15987986 30748 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 1 4 4.0 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3ccc(C)c(F)c3)c21 nan
CHEMBL1395557 30748 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 6 1 4 4.0 CCC(=O)N1CCc2cc(Br)cc(S(=O)(=O)CCC(=O)Nc3ccc(C)c(F)c3)c21 nan
16009626 30762 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 3 5.7 Cc1cc(C)cc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)c1 nan
CHEMBL1395778 30762 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 3 5.7 Cc1cc(C)cc(C(=O)Nc2c(C(=O)Nc3ccccc3F)oc3ccccc23)c1 nan
16017553 30785 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 2.7 O=C(Nc1nnc(S(=O)(=O)N2CCCCC2)s1)c1ccccc1Br nan
CHEMBL1396131 30785 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 2.7 O=C(Nc1nnc(S(=O)(=O)N2CCCCC2)s1)c1ccccc1Br nan
16033012 30810 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 4 0 7 3.3 O=C(Cn1c(=O)n2nc(-c3cccc(F)c3)nc2c2ccccc21)N1CCN(c2ccccc2F)CC1 nan
CHEMBL1396543 30810 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 4 0 7 3.3 O=C(Cn1c(=O)n2nc(-c3cccc(F)c3)nc2c2ccccc21)N1CCN(c2ccccc2F)CC1 nan
15989006 30817 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 8 3.5 O=C(CCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1396634 30817 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 8 3.5 O=C(CCn1c(=O)c2sccc2n(Cc2ccc(F)cc2Cl)c1=O)NCc1ccc2c(c1)OCO2 nan
16009460 30840 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 3.6 COc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1OC nan
CHEMBL1396932 30840 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 8 3.6 COc1ccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)cc1OC nan
3408184 30851 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 5 5.8 CCOc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
CHEMBL1397049 30851 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 7 1 5 5.8 CCOc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3)n2)cc1 nan
4345038 30856 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 3 5.2 CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)c(C(=O)Nc2cccc(Cl)c2Cl)c1 nan
CHEMBL1397130 30856 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 6 1 3 5.2 CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)c(C(=O)Nc2cccc(Cl)c2Cl)c1 nan
16017005 30858 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.9 CCOc1ccc(NC(=O)C(=O)c2cc(C)n(-c3cc(C)cc(C)c3)c2C)cc1 nan
CHEMBL1397170 30858 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.9 CCOc1ccc(NC(=O)C(=O)c2cc(C)n(-c3cc(C)cc(C)c3)c2C)cc1 nan
16009843 30920 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 1 6 3.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1398005 30920 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 4 1 6 3.4 O=C(Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
15988021 30936 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 12 2 10 1.0 COCCNC(=O)CCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)Nc2ccccc2OC)c1=O nan
CHEMBL1398191 30936 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 514 12 2 10 1.0 COCCNC(=O)CCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)Nc2ccccc2OC)c1=O nan
2288826 31119 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 3 4 0.6 O=C1NC(=O)C(=CNc2cc(F)cc(F)c2)C(=O)N1 nan
CHEMBL1400030 31119 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 3 4 0.6 O=C1NC(=O)C(=CNc2cc(F)cc(F)c2)C(=O)N1 nan
16009302 31202 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.7 Cn1c2ccccc2c2cnn(CC(=O)Nc3ccccc3F)c(=O)c21 nan
CHEMBL1400803 31202 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 5 2.7 Cn1c2ccccc2c2cnn(CC(=O)Nc3ccccc3F)c(=O)c21 nan
16010052 31216 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 5 4.9 COc1ccc(CCNC(=O)Cn2c(-c3cccs3)cc3cc(F)ccc32)cc1OC nan
CHEMBL1400938 31216 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 8 1 5 4.9 COc1ccc(CCNC(=O)Cn2c(-c3cccs3)cc3cc(F)ccc32)cc1OC nan
16022925 31357 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 0 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)N(C)Cc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1402121 31357 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 5 0 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)N(C)Cc5ccccc5)CC4)nnc(C)c3c2C)cc1 nan
3238641 31405 37 None -354 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 5 1 3 3.0 COc1ccc(OCc2cccc(C(=O)O)c2)cc1 nan
CHEMBL1402510 31405 37 None -354 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 5 1 3 3.0 COc1ccc(OCc2cccc(C(=O)O)c2)cc1 nan
24792811 31416 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 5 4.4 Cc1cccc(N2CCN(c3ccc4cc(S(=O)(=O)N5CCCCC5)ccc4n3)CC2C)c1 nan
CHEMBL1402620 31416 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 5 4.4 Cc1cccc(N2CCN(c3ccc4cc(S(=O)(=O)N5CCCCC5)ccc4n3)CC2C)c1 nan
13020032 31452 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 5 2.9 COc1ccc(C[C@H]2c3cc(O)c(OC)cc3CC[N+]2(C)[O-])cc1O nan
CHEMBL1402907 31452 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 5 2.9 COc1ccc(C[C@H]2c3cc(O)c(OC)cc3CC[N+]2(C)[O-])cc1O nan
3456065 31456 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 4 4.8 Oc1nnc(Cc2ccc(-c3ccc(Cl)cc3)o2)c2ccccc12 nan
CHEMBL1402979 31456 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 4 4.8 Oc1nnc(Cc2ccc(-c3ccc(Cl)cc3)o2)c2ccccc12 nan
807671 31493 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 2 4 2.7 Cc1nc(NC(=O)c2ccccc2O)sc1C nan
CHEMBL1403354 31493 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 2 4 2.7 Cc1nc(NC(=O)c2ccccc2O)sc1C nan
24979173 31533 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 3.2 COc1ccccc1NC(=O)COC(=O)c1ccccc1SCC(=O)N1CCCC1 nan
CHEMBL1403792 31533 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 3.2 COc1ccccc1NC(=O)COC(=O)c1ccccc1SCC(=O)N1CCCC1 nan
1300573 31543 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 4.7 Cc1cccc(NC(=O)Cn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)c1 nan
CHEMBL1403862 31543 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 4.7 Cc1cccc(NC(=O)Cn2nc(-c3ccc(Cl)cc3)c3ccccc3c2=O)c1 nan
3176404 31593 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 5 2 3 3.9 Cc1cccc(CCNCc2cc3cccc(C)c3nc2O)c1 nan
CHEMBL1404217 31593 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 5 2 3 3.9 Cc1cccc(CCNCc2cc3cccc(C)c3nc2O)c1 nan
2941406 31650 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 1 2 5 4.2 Cc1c(C#N)c(N)nc2c3c(sc12)NC(=O)CC3c1ccc(Cl)cc1 nan
CHEMBL1404915 31650 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 1 2 5 4.2 Cc1c(C#N)c(N)nc2c3c(sc12)NC(=O)CC3c1ccc(Cl)cc1 nan
663707 31735 15 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 4 4.8 Fc1ccc(CSc2ncnc3c2oc2ccccc23)cc1 nan
CHEMBL1405769 31735 15 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 0 4 4.8 Fc1ccc(CSc2ncnc3c2oc2ccccc23)cc1 nan
3207570 31744 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.1 CCc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1405871 31744 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.1 CCc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
2102520 31899 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 1 7 5.0 COc1cc(C(=O)Nc2nc3ccc(C)cc3s2)ccc1OCc1c(C)noc1C nan
CHEMBL1407262 31899 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 1 7 5.0 COc1cc(C(=O)Nc2nc3ccc(C)cc3s2)ccc1OCc1c(C)noc1C nan
672442 31984 15 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 5 3.3 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccc(Cl)cc1 nan
CHEMBL1407760 31984 15 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 1 5 3.3 N#Cc1c(N)nc(N2CCCC2)c(C#N)c1-c1ccc(Cl)cc1 nan
15989447 31995 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 1 5 4.1 O=C(CCCn1c(=O)c2ccccc2n(Cc2cccc(F)c2)c1=O)NCc1ccccc1Cl nan
CHEMBL1407901 31995 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 8 1 5 4.1 O=C(CCCn1c(=O)c2ccccc2n(Cc2cccc(F)c2)c1=O)NCc1ccccc1Cl nan
5524322 32031 18 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 4.5 CSc1nsc(/C=C/Nc2cccc(Cl)c2)c1C#N nan
CHEMBL1408147 32031 18 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 5 4.5 CSc1nsc(/C=C/Nc2cccc(Cl)c2)c1C#N nan
135454349 32115 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 2 6 2.6 CCc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
CHEMBL1408793 32115 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 2 6 2.6 CCc1ccc(N2CC(=O)C(c3nc(O)c4ccccc4n3)=C2N)cc1 nan
16012616 32165 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccccc5F)s4)c3nc12 nan
CHEMBL1409190 32165 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 4 0 10 3.5 Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nnc(SCc5ccccc5F)s4)c3nc12 nan
16026074 32222 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.1 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccccc2C)CC1 nan
CHEMBL1409660 32222 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 4 1 4 4.1 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccccc2C)CC1 nan
5294544 32231 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 1 1 4 2.4 CCn1c(=S)[nH]c2nc3c(cc2c1=O)CCCC3 nan
CHEMBL1409738 32231 16 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 261 1 1 4 2.4 CCn1c(=S)[nH]c2nc3c(cc2c1=O)CCCC3 nan
3208202 32273 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 3 7 3.3 CCc1cc2c(C)ccc(C)c2nc1SCC(=O)Nc1cnc(O)nc1O nan
CHEMBL1410014 32273 8 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 5 3 7 3.3 CCc1cc2c(C)ccc(C)c2nc1SCC(=O)Nc1cnc(O)nc1O nan
2136000 32282 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
CHEMBL1410088 32282 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3cc4c(cc32)OCCO4)cc1 nan
2056596 32396 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 2 5 2.6 CCn1ncc(Br)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2 nan
CHEMBL1411085 32396 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 2 5 2.6 CCn1ncc(Br)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2 nan
15988949 32410 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(NC(=O)Cn2c(=O)n(CCCCCC(=O)NCc3ccc(F)cc3)c(=O)c3sccc32)cc1C nan
CHEMBL1411183 32410 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 11 2 7 4.5 Cc1ccc(NC(=O)Cn2c(=O)n(CCCCCC(=O)NCc3ccc(F)cc3)c(=O)c3sccc32)cc1C nan
4390376 32439 4 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1 nan
CHEMBL1411409 32439 4 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1 nan
627327 32499 34 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 0 3 3.6 O=c1oc(-c2ccc(Br)cc2)nc2ccccc12 nan
CHEMBL1411919 32499 34 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 0 3 3.6 O=c1oc(-c2ccc(Br)cc2)nc2ccccc12 nan
16017002 32537 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.8 CCOc1ccc(CNC(=O)C(C)n2ncn3cccc3c2=O)cc1 nan
CHEMBL1412238 32537 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 6 1 6 1.8 CCOc1ccc(CNC(=O)C(C)n2ncn3cccc3c2=O)cc1 nan
16026072 32586 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 5 4.2 CCOc1ccccc1CNC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
CHEMBL1412601 32586 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 5 4.2 CCOc1ccccc1CNC(=O)C1CCN(C2=NS(=O)(=O)C(c3ccc(C)c(C)c3)=C2C)CC1 nan
646655 32597 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1412670 32597 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 2.8 Cc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
1246434 32601 14 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 5 4.7 O=C(Nc1nnc(C2CCCCC2)s1)c1ccc(Br)s1 nan
CHEMBL1412704 32601 14 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 5 4.7 O=C(Nc1nnc(C2CCCCC2)s1)c1ccc(Br)s1 nan
1952877 32621 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 2 5 2.0 Cc1cc(C)c2oc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc(=O)c2c1 nan
CHEMBL1412873 32621 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 2 5 2.0 Cc1cc(C)c2oc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc(=O)c2c1 nan
16017227 32646 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 6 2.2 Cc1nn(CC(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c(=O)c2cccn12 nan
CHEMBL1413003 32646 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 6 2.2 Cc1nn(CC(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c(=O)c2cccn12 nan
15996885 32654 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1cccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)c1 nan
CHEMBL1413061 32654 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1cccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)c1 nan
2314879 32703 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 6 3.3 CCCCn1c2nc3ccccc3nc2c2c(=N)oc(C)nc21 nan
CHEMBL1413521 32703 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 6 3.3 CCCCn1c2nc3ccccc3nc2c2c(=N)oc(C)nc21 nan
694926 32718 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 1 5 3.3 Cc1cccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1 nan
CHEMBL1413648 32718 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 3 1 5 3.3 Cc1cccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)c1 nan
16025383 32828 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 6 4.4 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)NCCc1ccccc1 nan
CHEMBL1414539 32828 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 8 1 6 4.4 O=C(CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(F)cc1)S2(=O)=O)NCCc1ccccc1 nan
16010143 32893 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 3 5.6 Cc1ccc(Cn2c(C(=O)NCc3ccccc3Cl)cc3sccc32)cc1 nan
CHEMBL1415124 32893 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 3 5.6 Cc1ccc(Cn2c(C(=O)NCc3ccccc3Cl)cc3sccc32)cc1 nan
663372 32895 14 None -14 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 4 4.2 Cc1ccc(C2CC(=O)c3cnc(N4CC(C)CC(C)C4)nc3C2)cc1 nan
CHEMBL1415139 32895 14 None -14 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 4 4.2 Cc1ccc(C2CC(=O)c3cnc(N4CC(C)CC(C)C4)nc3C2)cc1 nan
16029519 32906 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 5 0 6 2.9 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3cccc(Cl)c3)CC1)CCS2 nan
CHEMBL1415234 32906 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 5 0 6 2.9 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3cccc(Cl)c3)CC1)CCS2 nan
1088534 32940 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 1 4 3.9 CCOc1ccc(NC(=O)Cn2cc(C(C)=O)c3ccccc32)cc1 nan
CHEMBL1415529 32940 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 1 4 3.9 CCOc1ccc(NC(=O)Cn2cc(C(C)=O)c3ccccc32)cc1 nan
2701522 32963 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 6 1 6 2.8 CCSc1nnc(NC(=O)Cc2ccccc2OC)s1 nan
CHEMBL1415759 32963 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 6 1 6 2.8 CCSc1nnc(NC(=O)Cc2ccccc2OC)s1 nan
20880977 33067 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 8 2.5 O=C(CCc1nnc2n(Cc3ccc(Cl)cc3)c(=O)c3ccccc3n12)NCCCN1CCOCC1 nan
CHEMBL1416665 33067 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 9 1 8 2.5 O=C(CCc1nnc2n(Cc3ccc(Cl)cc3)c(=O)c3ccccc3n12)NCCCN1CCOCC1 nan
16025415 33084 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 1 6 5.5 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)c1 nan
CHEMBL1416823 33084 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 6 1 6 5.5 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2ccccc2C)S3(=O)=O)c1 nan
24792644 33220 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.8 CN(C)c1ccc(-c2ccc3c(=O)c4ccccc4n(C)c3c2)cn1 nan
CHEMBL1417964 33220 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.8 CN(C)c1ccc(-c2ccc3c(=O)c4ccccc4n(C)c3c2)cn1 nan
16030529 33235 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 0 4 5.8 CCN(C(=O)CSc1nc2ccccc2nc1Cc1ccc(F)cc1)c1cccc(C)c1 nan
CHEMBL1418101 33235 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 7 0 4 5.8 CCN(C(=O)CSc1nc2ccccc2nc1Cc1ccc(F)cc1)c1cccc(C)c1 nan
1936615 33298 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 7 4.5 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccccc5)ncnc4c3cc2CO1 nan
CHEMBL1418632 33298 11 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 7 4.5 CC1(C)Cc2nc3sc4c(SCC(=O)NCc5ccccc5)ncnc4c3cc2CO1 nan
3574260 33371 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
CHEMBL1419267 33371 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccccc1Cl nan
5069803 33839 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 4 2.2 CC(C)C(=O)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1 nan
CHEMBL1423181 33839 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 0 4 2.2 CC(C)C(=O)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1 nan
4298772 33899 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 3 1 4 2.8 Cc1ccc(NC(=O)c2ccc(-n3cccn3)nc2)cc1 nan
CHEMBL1423637 33899 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 3 1 4 2.8 Cc1ccc(NC(=O)c2ccc(-n3cccn3)nc2)cc1 nan
135521903 33962 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1ccc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)cc1Cl nan
CHEMBL1424164 33962 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1ccc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)cc1Cl nan
5009230 34240 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 1 3 4.6 O=c1c2ccc(Cl)cc2[nH]c(=S)n1CCC1=CCCCC1 nan
CHEMBL1426475 34240 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 1 3 4.6 O=c1c2ccc(Cl)cc2[nH]c(=S)n1CCC1=CCCCC1 nan
1004501 34257 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 8 1 6 5.8 COc1ccc(-c2cc(-c3cccs3)c(C#N)c(SCC(=O)NCc3ccccc3)n2)cc1 nan
CHEMBL1426581 34257 13 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 8 1 6 5.8 COc1ccc(-c2cc(-c3cccs3)c(C#N)c(SCC(=O)NCc3ccccc3)n2)cc1 nan
1398121 34280 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 4 5.1 Cc1nc(Nc2ccccc2)c2oc3ccc(Cl)cc3c2n1 nan
CHEMBL1426816 34280 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 2 1 4 5.1 Cc1nc(Nc2ccccc2)c2oc3ccc(Cl)cc3c2n1 nan
2916457 34339 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 0 4 2.1 O=C1c2nc3ccccn3c2C(=O)N1Cc1ccccc1 nan
CHEMBL1427322 34339 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 277 2 0 4 2.1 O=C1c2nc3ccccn3c2C(=O)N1Cc1ccccc1 nan
2785858 34579 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 0 5 0.8 Cn1c(=O)c2cc3ccccc3nc2n(C)c1=O nan
CHEMBL1429441 34579 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 0 5 0.8 Cn1c(=O)c2cc3ccccc3nc2n(C)c1=O nan
1474449 34828 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 5 3.8 Nc1c(-c2cccs2)cnc2c(-c3ccc(F)cc3)cnn12 nan
CHEMBL1431364 34828 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 2 1 5 3.8 Nc1c(-c2cccs2)cnc2c(-c3ccc(F)cc3)cnn12 nan
22548378 34833 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 6 2.0 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3cc4c(cc3C)NC(=O)CO4)CC2)cc1 nan
CHEMBL1431452 34833 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 4 1 6 2.0 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3cc4c(cc3C)NC(=O)CO4)CC2)cc1 nan
3239990 34889 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 3 0 7 3.1 CCOC(=O)N1CCN(C(=O)c2nn(-c3ccc(C)cc3)c(=O)c3c2c2ccccc2n3C)CC1 nan
CHEMBL1431956 34889 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 3 0 7 3.1 CCOC(=O)N1CCN(C(=O)c2nn(-c3ccc(C)cc3)c(=O)c3c2c2ccccc2n3C)CC1 nan
1480466 34908 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2cccnc2)nc(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1432166 34908 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2cccnc2)nc(-c2ccc(Cl)cc2)c1C#N nan
24792375 34929 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 2.5 COc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
CHEMBL1432321 34929 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 2.5 COc1ccc2nc(SCC(=O)NCC3CCCO3)c(C#N)cc2c1 nan
1049756 35060 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 5 4.3 COc1ccccc1NC(=O)c1c(NC(=O)c2ccco2)sc2c1CCC2 nan
CHEMBL1433354 35060 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 5 2 5 4.3 COc1ccccc1NC(=O)c1c(NC(=O)c2ccco2)sc2c1CCC2 nan
2227785 35073 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 7 5.3 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1 nan
CHEMBL1433437 35073 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 7 1 7 5.3 COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1 nan
16027247 35085 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 4.9 COc1ccc2ncc3c(-c4ccc(C)c(C)c4)nn(CC(=O)NC4CCCC4)c3c2c1 nan
CHEMBL1433603 35085 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 4.9 COc1ccc2ncc3c(-c4ccc(C)c(C)c4)nn(CC(=O)NC4CCCC4)c3c2c1 nan
16024617 35106 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 7 1 6 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)c(Cl)c3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1433920 35106 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 7 1 6 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)c(Cl)c3)c3nc(C)ccc3c2=O)cc1 nan
16019055 35125 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccccc1CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1434234 35125 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccccc1CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
2135389 35128 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 6 4.0 COc1cccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc(OC)ccc32)c1 nan
CHEMBL1434264 35128 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 7 1 6 4.0 COc1cccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc(OC)ccc32)c1 nan
16026966 35134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1434365 35134 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
16021030 35145 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 3 5.9 CC(CNC(=O)Cn1c(-c2cccs2)cc2cc(Cl)ccc21)c1ccccc1 nan
CHEMBL1434633 35145 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 3 5.9 CC(CNC(=O)Cn1c(-c2cccs2)cc2cc(Cl)ccc21)c1ccccc1 nan
2134800 35179 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 9 1 7 4.1 COCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1435016 35179 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 9 1 7 4.1 COCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
16022354 35206 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 6 4.9 Cc1ccc(Cn2c(SCC(=O)NCc3ccc(Cl)cc3)nc3ccsc3c2=O)cc1 nan
CHEMBL1435272 35206 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 1 6 4.9 Cc1ccc(Cn2c(SCC(=O)NCc3ccc(Cl)cc3)nc3ccsc3c2=O)cc1 nan
16022956 35246 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.7 Cc1nnc(N2CCC(C(=O)NCCc3ccccc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
CHEMBL1435842 35246 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 6 4.7 Cc1nnc(N2CCC(C(=O)NCCc3ccccc3)CC2)c2nn(-c3ccc(Cl)cc3)c(C)c12 nan
16015098 35247 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.5 Cc1nc(SCC(=O)Nc2ccccc2C)cc(-c2ccccc2)n1 nan
CHEMBL1435853 35247 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.5 Cc1nc(SCC(=O)Nc2ccccc2C)cc(-c2ccccc2)n1 nan
16024515 35251 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 4.5 COc1ccc(Cl)cc1NC(=O)Cn1cc(C(=O)c2ccc(C)cc2)c(=O)c2ccc(C)nc21 nan
CHEMBL1435881 35251 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 1 6 4.5 COc1ccc(Cl)cc1NC(=O)Cn1cc(C(=O)c2ccc(C)cc2)c(=O)c2ccc(C)nc21 nan
16025955 35260 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccccc1Cl)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1436007 35260 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccccc1Cl)c1cnc2sc(N3CCOCC3)nn2c1=O nan
15988055 35282 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 2 1 8 3.4 Cc1cccc(C)c1Nc1nn2c(=O)c3cc4c(cc3nc2s1)OCO4 nan
CHEMBL1436214 35282 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 2 1 8 3.4 Cc1cccc(C)c1Nc1nn2c(=O)c3cc4c(cc3nc2s1)OCO4 nan
1166237 35293 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 7 5.4 CCOc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)cc1 nan
CHEMBL1436413 35293 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 8 1 7 5.4 CCOc1ccc(NC(=O)CCSc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2)cc1 nan
4076476 35311 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1cccc(C(=O)Nc2c(C(=O)c3ccc(F)cc3)oc3ccccc23)c1 nan
CHEMBL1436707 35311 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1cccc(C(=O)Nc2c(C(=O)c3ccc(F)cc3)oc3ccccc23)c1 nan
16012965 35318 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 3 5.3 CCCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
CHEMBL1436801 35318 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 3 5.3 CCCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
16031323 35323 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 8 1 8 3.7 COc1cc(-c2cc3n(C)c(C)c(CCC(=O)Nc4ccc(F)cc4)c(=O)n3n2)cc(OC)c1OC nan
CHEMBL1436894 35323 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 8 1 8 3.7 COc1cc(-c2cc3n(C)c(C)c(CCC(=O)Nc4ccc(F)cc4)c(=O)n3n2)cc(OC)c1OC nan
3533132 35402 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 3.3 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cncc(Br)c1 nan
CHEMBL1437784 35402 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 3.3 COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)c1cncc(Br)c1 nan
4650106 35444 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 2 5 4.2 O=C(NCc1cccnc1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
CHEMBL1438098 35444 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 2 5 4.2 O=C(NCc1cccnc1)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
959085 35530 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 4 3.5 CC(=O)c1sc(NC(=O)c2ccc(C)c(C)c2)nc1C nan
CHEMBL1438925 35530 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 1 4 3.5 CC(=O)c1sc(NC(=O)c2ccc(C)c(C)c2)nc1C nan
16026319 35551 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(C)c(F)c4)c32)cc1 nan
CHEMBL1439096 35551 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 5 4.5 CCc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4ccc(C)c(F)c4)c32)cc1 nan
16015553 35553 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 2 6 5.2 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccco4)cc3s2)cc1 nan
CHEMBL1439122 35553 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 6 2 6 5.2 Cc1ccc(NC(=O)CSc2nc3ccc(NC(=O)c4ccco4)cc3s2)cc1 nan
15988982 35674 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 524 8 2 7 3.8 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(CCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
CHEMBL1440158 35674 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 524 8 2 7 3.8 Cc1cccc(C)c1NC(=O)Cn1c(=O)n(CCC(=O)NCc2ccccc2Cl)c(=O)c2sccc21 nan
2137007 35914 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.8 COCCNc1nc2c(S(=O)(=O)c3cc(C)ccc3C)nnn2c2ccccc12 nan
CHEMBL1442335 35914 9 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 8 2.8 COCCNc1nc2c(S(=O)(=O)c3cc(C)ccc3C)nnn2c2ccccc12 nan
3156591 35932 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 3.0 CCCNS(=O)(=O)c1cc(-c2nnc3c4ccccc4c(C)nn23)ccc1OC nan
CHEMBL1442508 35932 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 1 7 3.0 CCCNS(=O)(=O)c1cc(-c2nnc3c4ccccc4c(C)nn23)ccc1OC nan
16009539 35972 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4F)cc3)cc(=O)n12 nan
CHEMBL1442799 35972 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 3.8 Cc1csc2nc(COc3ccc(NC(=O)COc4ccccc4F)cc3)cc(=O)n12 nan
1119348 35990 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 0 6 4.2 COc1cccc2cc(-c3nnc(-c4ccc(Cl)cc4)o3)c(=O)oc12 nan
CHEMBL1443005 35990 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 0 6 4.2 COc1cccc2cc(-c3nnc(-c4ccc(Cl)cc4)o3)c(=O)oc12 nan
3456574 36170 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 2 5 1.8 COCCn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
CHEMBL1444789 36170 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 5 2 5 1.8 COCCn1c(=S)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O nan
15987577 36186 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.3 Cc1cc(Cl)ccc1OCC(=O)Nc1c(Cl)ccc2nsnc12 nan
CHEMBL1444928 36186 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.3 Cc1cc(Cl)ccc1OCC(=O)Nc1c(Cl)ccc2nsnc12 nan
1529015 36188 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 5.3 CCOC(=O)c1c(-c2ccc(C)s2)csc1NC(=O)c1cccs1 nan
CHEMBL1444931 36188 15 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 6 5.3 CCOC(=O)c1c(-c2ccc(C)s2)csc1NC(=O)c1cccs1 nan
3238506 36221 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 7 3.0 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nc4ccccc4s3)cc2)CC1 nan
CHEMBL1445199 36221 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 1 7 3.0 CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)Nc3nc4ccccc4s3)cc2)CC1 nan
629629 36238 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 3 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 nan
CHEMBL1445350 36238 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 3 5.4 CC(=O)Nc1ccc(-c2cc(-c3ccccc3)nc(-c3ccccc3)n2)cc1 nan
16008367 36265 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 1 6 4.6 COc1cc(OC)c(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1Cl nan
CHEMBL1445604 36265 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 1 6 4.6 COc1cc(OC)c(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1Cl nan
16031877 36292 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 4.0 CCOC(=O)C1CCCN(Cc2cn3c(-c4ccc(Br)cc4)nnc3s2)C1 nan
CHEMBL1445888 36292 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 0 7 4.0 CCOC(=O)C1CCCN(Cc2cn3c(-c4ccc(Br)cc4)nnc3s2)C1 nan
3116123 36312 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
CHEMBL1446094 36312 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
3462774 36348 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 2 5 3.6 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
CHEMBL1446438 36348 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 8 2 5 3.6 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
1478332 36578 23 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.1 CCOC(=O)c1cc2c(=O)c3cc(C)ccc3oc2nc1C nan
CHEMBL1448380 36578 23 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.1 CCOC(=O)c1cc2c(=O)c3cc(C)ccc3oc2nc1C nan
15990626 36605 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 6.1 CCOc1ccc2ncc3c(-c4ccc(C)cc4)nn(-c4cccc(F)c4)c3c2c1 nan
CHEMBL1448570 36605 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 6.1 CCOc1ccc2ncc3c(-c4ccc(C)cc4)nn(-c4cccc(F)c4)c3c2c1 nan
16007612 36641 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 1 5 3.8 Cc1ccc(CCNC(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)cc1 nan
CHEMBL1448823 36641 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 1 5 3.8 Cc1ccc(CCNC(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)cc1 nan
2201274 36683 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 6 3.5 COc1cccc(-c2nnc(NC(=O)Cc3cccs3)s2)c1 nan
CHEMBL1449110 36683 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 5 1 6 3.5 COc1cccc(-c2nnc(NC(=O)Cc3cccs3)s2)c1 nan
16017301 36857 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 7 3.2 CC(C)CN(c1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2ccco2)s1 nan
CHEMBL1450497 36857 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 7 1 7 3.2 CC(C)CN(c1ccccc1)S(=O)(=O)c1nnc(NC(=O)c2ccco2)s1 nan
3646626 36874 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 5.3 CC(C)OCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1450646 36874 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 5.3 CC(C)OCCCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
1389502 36924 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 1 3 4.0 O=C(Nc1cc(Cl)cc(Cl)c1)c1coc(=O)c(Br)c1 nan
CHEMBL1451156 36924 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 2 1 3 4.0 O=C(Nc1cc(Cl)cc(Cl)c1)c1coc(=O)c(Br)c1 nan
653554 36982 11 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(-c3ccccc3)c(=O)c2c1C nan
CHEMBL1451583 36982 11 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.1 Cc1sc2nc(SCC(=O)NCc3ccco3)n(-c3ccccc3)c(=O)c2c1C nan
135476823 36986 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 2.7 Cc1cccc(-n2c(SCC(=O)N3CCCC3)nc3nnc(C)c-3c2N)c1 nan
CHEMBL1451599 36986 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 7 2.7 Cc1cccc(-n2c(SCC(=O)N3CCCC3)nc3nnc(C)c-3c2N)c1 nan
2029273 37073 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 6 5.2 COc1cccc(-c2ccc(-c3noc(-c4ccccc4Br)n3)c(OC)n2)c1 nan
CHEMBL1452203 37073 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 6 5.2 COc1cccc(-c2ccc(-c3noc(-c4ccccc4Br)n3)c(OC)n2)c1 nan
5058847 37084 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
CHEMBL1452293 37084 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
16027444 37114 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
CHEMBL1452550 37114 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 460 6 1 8 3.9 Cc1cccc(C(=O)Nc2ccc(C(=O)OCc3cc(=O)n4nc(C5CC5)sc4n3)cc2)c1 nan
4256434 37277 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 5.1 Cc1ccc(-c2nc(NC(=O)CSc3cc(C)c4ccccc4n3)ns2)cc1 nan
CHEMBL1453902 37277 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 1 6 5.1 Cc1ccc(-c2nc(NC(=O)CSc3cc(C)c4ccccc4n3)ns2)cc1 nan
16008459 37283 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 0 4 4.8 CCOc1ccc2c(c1)c(=O)c(C(=O)c1ccccc1)cn2Cc1ccccc1F nan
CHEMBL1453936 37283 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 0 4 4.8 CCOc1ccc2c(c1)c(=O)c(C(=O)c1ccccc1)cn2Cc1ccccc1F nan
991456 37309 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 4 4.1 COc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NCc2ccco2)cc1 nan
CHEMBL1454096 37309 3 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 2 4 4.1 COc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NCc2ccco2)cc1 nan
808336 37377 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 0 6 1.8 Cc1ccc(-c2nn3c(=O)c(C)nnc3s2)cc1 nan
CHEMBL1454681 37377 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 1 0 6 1.8 Cc1ccc(-c2nn3c(=O)c(C)nnc3s2)cc1 nan
16017701 37380 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 3.9 CCC(Sc1nc2nccnc2c(=O)n1Cc1ccc(C)cc1)C(=O)NC1CCCCC1 nan
CHEMBL1454690 37380 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 3.9 CCC(Sc1nc2nccnc2c(=O)n1Cc1ccc(C)cc1)C(=O)NC1CCCCC1 nan
15988663 37400 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 5 3.9 COc1ccc(OC)c(-c2cc(C(=O)NCc3ccc(Cl)cc3)no2)c1 nan
CHEMBL1454826 37400 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 6 1 5 3.9 COc1ccc(OC)c(-c2cc(C(=O)NCc3ccc(Cl)cc3)no2)c1 nan
599450 37497 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 1 3 3.6 O=C(Nc1ccc2c(c1)C(=O)OC2)c1ccc(C(F)(F)F)cc1 nan
CHEMBL1455771 37497 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 1 3 3.6 O=C(Nc1ccc2c(c1)C(=O)OC2)c1ccc(C(F)(F)F)cc1 nan
3981165 37529 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 5 2.5 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 nan
CHEMBL1456046 37529 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 5 2.5 CCOc1ncccc1C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 nan
15989547 37544 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 8 1 5 3.6 O=C(CCn1c(=O)c2ccccc2n(Cc2cccc(Cl)c2)c1=O)NCCc1ccccc1 nan
CHEMBL1456174 37544 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 8 1 5 3.6 O=C(CCn1c(=O)c2ccccc2n(Cc2cccc(Cl)c2)c1=O)NCCc1ccccc1 nan
16027694 37579 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2ccsc2n1 nan
CHEMBL1456495 37579 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2ccsc2n1 nan
3242698 37609 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 2 7 4.2 Cc1ccccc1NC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1456820 37609 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 2 7 4.2 Cc1ccccc1NC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
16024703 37662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1457278 37662 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NC3CCCCC3)c2n1 nan
7066852 37672 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 2 3 5.8 Cc1ccc2nc(-c3c[nH]c4ccccc34)c(Nc3ccccc3C)n2c1 nan
CHEMBL1457410 37672 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 2 3 5.8 Cc1ccc2nc(-c3c[nH]c4ccccc34)c(Nc3ccccc3C)n2c1 nan
16030759 37688 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 0 6 4.4 O=C(c1ccc2c(c1)OCCO2)N(Cc1cccnc1)c1nc2ccc(F)cc2s1 nan
CHEMBL1457518 37688 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 0 6 4.4 O=C(c1ccc2c(c1)OCCO2)N(Cc1cccnc1)c1nc2ccc(F)cc2s1 nan
3347951 37694 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.5 CNC(=O)C(Sc1nc(C)nc2c1oc1ccccc12)C(C)=O nan
CHEMBL1457585 37694 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 6 2.5 CNC(=O)C(Sc1nc(C)nc2c1oc1ccccc12)C(C)=O nan
654954 37811 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 3.4 Cc1ccc2nc(SCC(=O)NCc3ccco3)c(C#N)cc2c1 nan
CHEMBL1458514 37811 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 5 3.4 Cc1ccc2nc(SCC(=O)NCc3ccco3)c(C#N)cc2c1 nan
861942 37868 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 0 6 3.7 COc1ccc(OC)c(-c2csc(N(C)C(=O)c3ccco3)n2)c1 nan
CHEMBL1458992 37868 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 0 6 3.7 COc1ccc(OC)c(-c2csc(N(C)C(=O)c3ccco3)n2)c1 nan
2570053 38149 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 0 7 1.8 Cc1ccnc2nc(C(=O)OCCOc3ccc(F)cc3)nn12 nan
CHEMBL1461384 38149 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 5 0 7 1.8 Cc1ccnc2nc(C(=O)OCCOc3ccc(F)cc3)nn12 nan
2109478 38175 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 4 1 5 3.9 Cc1cc(NC(=O)COc2ccc3oc4ccccc4c3c2)no1 nan
CHEMBL1461645 38175 2 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 4 1 5 3.9 Cc1cc(NC(=O)COc2ccc3oc4ccccc4c3c2)no1 nan
3243431 38183 7 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 4 5.6 CCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccco3)c(Cl)c2)cc1Br nan
CHEMBL1461732 38183 7 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 4 5.6 CCOc1ccc(C(=O)Nc2ccc(NC(=O)c3ccco3)c(Cl)c2)cc1Br nan
24789924 38274 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1ccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)cc1 nan
CHEMBL1462423 38274 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 8 1 8 3.7 COc1ccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)cc1 nan
651585 38302 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 7 2.1 COC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
CHEMBL1462713 38302 5 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 7 2.1 COC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 nan
2134888 38307 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 9 2.4 COc1ccc(C=O)cc1Cn1c(=O)n(CCC(=O)NCc2ccco2)c(=O)c2sccc21 nan
CHEMBL1462748 38307 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 9 1 9 2.4 COc1ccc(C=O)cc1Cn1c(=O)n(CCC(=O)NCc2ccco2)c(=O)c2sccc21 nan
658551 38603 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 7 2.0 CCCOC(=O)CSc1nc(N)c(C#N)c(CC)c1C#N nan
CHEMBL1465062 38603 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 6 1 7 2.0 CCCOC(=O)CSc1nc(N)c(C#N)c(CC)c1C#N nan
2571531 38628 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 0 10 3.3 CCCCn1c(SCc2cc(=O)n3ccsc3n2)nc2cc(C(=O)OC)ccc2c1=O nan
CHEMBL1465204 38628 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 0 10 3.3 CCCCn1c(SCc2cc(=O)n3ccsc3n2)nc2cc(C(=O)OC)ccc2c1=O nan
2207742 38630 8 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 6 3.8 CCc1c(C)sc(N=C(S)Nc2nc(C)cc(C)n2)c1C(=O)OC nan
CHEMBL1465216 38630 8 None -11 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 2 6 3.8 CCc1c(C)sc(N=C(S)Nc2nc(C)cc(C)n2)c1C(=O)OC nan
1299194 38812 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 8 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nnc(-c3cccs3)n2CC)cc1 nan
CHEMBL1466656 38812 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 8 1 8 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nnc(-c3cccs3)n2CC)cc1 nan
7502637 38866 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 3.3 COc1ccc(-c2ccc(SCC(=O)Nc3nccs3)nn2)cc1OC nan
CHEMBL1467089 38866 10 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 8 3.3 COc1ccc(-c2ccc(SCC(=O)Nc3nccs3)nn2)cc1OC nan
1086372 38882 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 5 4.7 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3cccc(Cl)c3)n2)c1 nan
CHEMBL1467241 38882 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 5 4.7 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3cccc(Cl)c3)n2)c1 nan
865458 38893 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 2 0 4 2.8 COc1ccc2nc(SC)c(C#N)cc2c1 nan
CHEMBL1467309 38893 6 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 230 2 0 4 2.8 COc1ccc2nc(SC)c(C#N)cc2c1 nan
20886167 39188 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.6 COc1cccc(CNC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
CHEMBL1469817 39188 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 1 5 2.6 COc1cccc(CNC(=O)Cn2c(=O)c3cccn3c3ccccc32)c1 nan
2045894 39198 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 0 5 4.9 Cc1ccc(-c2nc(=S)c3c(n2Cc2cccnc2)CC(C)(C)OC3)cc1 nan
CHEMBL1469903 39198 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 0 5 4.9 Cc1ccc(-c2nc(=S)c3c(n2Cc2cccnc2)CC(C)(C)OC3)cc1 nan
1035368 39319 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 4.2 COc1ccc2nc(NC(=O)CSc3nc4ccccc4o3)sc2c1 nan
CHEMBL1470920 39319 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 5 1 7 4.2 COc1ccc2nc(NC(=O)CSc3nc4ccccc4o3)sc2c1 nan
16009198 39497 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1472528 39497 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(OC)cc3)c3cc4c(cc3c2=O)OCO4)cc1 nan
15988292 39509 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 586 8 3 6 6.3 COCCCNC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(Cl)cc3)c(-c3ccc(Br)cc3)c2c1N nan
CHEMBL1472621 39509 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 586 8 3 6 6.3 COCCCNC(=O)c1sc2nc(C)c(C(=O)Nc3ccc(Cl)cc3)c(-c3ccc(Br)cc3)c2c1N nan
16027199 39530 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 3.7 CC(C)NC(=O)C1CCC(Cn2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)CC1 nan
CHEMBL1472919 39530 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 6 3.7 CC(C)NC(=O)C1CCC(Cn2c(=O)c3sccc3n(Cc3ccc(F)cc3)c2=O)CC1 nan
15988974 39534 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 12 2 7 4.6 CCc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc(C)cc2)c(=O)c2sccc21 nan
CHEMBL1472973 39534 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 12 2 7 4.6 CCc1ccccc1NC(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc(C)cc2)c(=O)c2sccc21 nan
9505887 39548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 0 6 2.3 N#Cc1ccc(OC(=O)C2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)cc1 nan
CHEMBL1473154 39548 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 2 0 6 2.3 N#Cc1ccc(OC(=O)C2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)cc1 nan
16021070 39552 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(OC)c(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1473236 39552 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 1 6 3.7 COc1ccc(OC)c(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
7786274 39560 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 5 3.0 O=C(COC(=O)c1cc(Br)ccc1O)Nc1cccnc1Cl nan
CHEMBL1473370 39560 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 4 2 5 3.0 O=C(COC(=O)c1cc(Br)ccc1O)Nc1cccnc1Cl nan
16017273 39575 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 1.7 Cc1nn(CC(=O)Nc2cc(F)ccc2F)c(=O)c2cccn12 nan
CHEMBL1473495 39575 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 3 1 5 1.7 Cc1nn(CC(=O)Nc2cc(F)ccc2F)c(=O)c2cccn12 nan
15990603 39611 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 5 6.2 CCOC(=O)c1ccc2ncc3c(-c4ccccc4)nn(-c4ccc(F)c(Cl)c4)c3c2c1 nan
CHEMBL1474033 39611 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 0 5 6.2 CCOC(=O)c1ccc2ncc3c(-c4ccccc4)nn(-c4ccc(F)c(Cl)c4)c3c2c1 nan
16015614 39631 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CC(C)C(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
CHEMBL1474414 39631 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CC(C)C(=O)Nc1ccc2nc(SCCOc3ccccc3)sc2c1 nan
16012115 39639 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 3.7 COc1cccc(CNC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)c1 nan
CHEMBL1474469 39639 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 3.7 COc1cccc(CNC(=O)Cn2ncc3c4ccccc4n(Cc4ccccc4)c3c2=O)c1 nan
15987618 39658 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 0 4 5.7 CCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(C(F)(F)F)c1 nan
CHEMBL1474699 39658 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 3 0 4 5.7 CCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(C(F)(F)F)c1 nan
16016392 39659 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 4.9 CC(C)NC(=O)N1[C@H](c2cccs2)[C@@H](C)C(=O)[C@@H](C)[C@@H]1c1cccs1 nan
CHEMBL1474706 39659 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 4.9 CC(C)NC(=O)N1[C@H](c2cccs2)[C@@H](C)C(=O)[C@@H](C)[C@@H]1c1cccs1 nan
15989047 39691 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 1 9 3.0 N#Cc1ccccc1Cn1c(=O)n(CCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
CHEMBL1475184 39691 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 1 9 3.0 N#Cc1ccccc1Cn1c(=O)n(CCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
1300955 39717 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1ccc(CNc2ncnc3c2cnn3-c2ccc(Cl)cc2)cc1 nan
CHEMBL1475511 39717 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1ccc(CNc2ncnc3c2cnn3-c2ccc(Cl)cc2)cc1 nan
16021946 39749 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 4 0 6 4.8 Cc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1CC(=O)c1ccc(Cl)cc1)n2C nan
CHEMBL1475915 39749 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 4 0 6 4.8 Cc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1CC(=O)c1ccc(Cl)cc1)n2C nan
16009716 39785 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 6 4.1 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
CHEMBL1476522 39785 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 4 1 6 4.1 O=C(Cn1c(=O)n(-c2ccccc2Cl)c(=O)c2sc3ccccc3c21)NC1CCCC1 nan
2387574 39875 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.0 CCS(=O)(=O)c1ccc2oc(Nc3cc(Cl)ccc3OC)nc2c1 nan
CHEMBL1477466 39875 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 5 1 6 4.0 CCS(=O)(=O)c1ccc2oc(Nc3cc(Cl)ccc3OC)nc2c1 nan
651813 39876 7 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 6 4.1 CCc1nc(SCC(=O)NCc2ccco2)c2c3c(sc2n1)CCCC3 nan
CHEMBL1477471 39876 7 None -7 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 1 6 4.1 CCc1nc(SCC(=O)NCc2ccco2)c2c3c(sc2n1)CCCC3 nan
135542325 39913 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.0 Cc1nnc2nc(SCC(=O)NC3CCCCC3)n(-c3ccc(Br)cc3)c(N)c1-2 nan
CHEMBL1477773 39913 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 5 2 7 4.0 Cc1nnc2nc(SCC(=O)NC3CCCCC3)n(-c3ccc(Br)cc3)c(N)c1-2 nan
4154279 39930 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 5 5.5 Cc1c(Cl)cccc1NC(=O)CSc1ncnc2c1sc1ccccc12 nan
CHEMBL1477945 39930 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 1 5 5.5 Cc1c(Cl)cccc1NC(=O)CSc1ncnc2c1sc1ccccc12 nan
647217 39978 1 None 1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 8 3.5 CCS(=O)(=O)Nc1ccc(-c2nnc(SCC(=O)c3cccc(OC)c3)o2)cc1 nan
CHEMBL1478450 39978 1 None 1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 9 1 8 3.5 CCS(=O)(=O)Nc1ccc(-c2nnc(SCC(=O)c3cccc(OC)c3)o2)cc1 nan
356316 40087 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 4 2.9 Cc1ccc(S(=O)(=O)c2cc3ccccc3oc2=O)cc1 nan
CHEMBL1479392 40087 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 0 4 2.9 Cc1ccc(S(=O)(=O)c2cc3ccccc3oc2=O)cc1 nan
16009796 40225 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 6 4.4 COc1ccc(-n2c(=O)c3sc4ccccc4c3n(Cc3ccccc3)c2=O)cc1 nan
CHEMBL1480505 40225 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 4 0 6 4.4 COc1ccc(-n2c(=O)c3sc4ccccc4c3n(Cc3ccccc3)c2=O)cc1 nan
16024583 40253 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
CHEMBL1480766 40253 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 5 1 7 3.5 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
3273049 40346 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 533 7 1 7 4.4 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C(C)C)C2 nan
CHEMBL1481475 40346 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 533 7 1 7 4.4 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C(C)C)C2 nan
3662250 40373 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 2.9 COc1ccc(-c2cc(C(=O)Nc3cc(C)on3)no2)cc1OC nan
CHEMBL1481783 40373 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 1 7 2.9 COc1ccc(-c2cc(C(=O)Nc3cc(C)on3)no2)cc1OC nan
5763301 40450 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 0 3 3.8 Cn1c(/C=C/c2ccc(Cl)cc2)nc2ccccc2c1=O nan
CHEMBL1482443 40450 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 0 3 3.8 Cn1c(/C=C/c2ccc(Cl)cc2)nc2ccccc2c1=O nan
16030274 40518 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 2 3 4.4 Cc1cccc2c(=O)cc(CSCC(=O)Nc3ccc(Cl)cc3)[nH]c12 nan
CHEMBL1483081 40518 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 2 3 4.4 Cc1cccc2c(=O)cc(CSCC(=O)Nc3ccc(Cl)cc3)[nH]c12 nan
135419126 40562 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 2 1 3 6.5 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2cccc(Br)c2)C1 nan
CHEMBL1483478 40562 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 2 1 3 6.5 Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(c2cccc(Br)c2)C1 nan
16010346 40577 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 0 7 5.0 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N(C)Cc2ccccc2)c2cc(Cl)ccc23)cc1C nan
CHEMBL1483574 40577 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 5 0 7 5.0 Cc1ccc(S(=O)(=O)c2nnn3c2nc(N(C)Cc2ccccc2)c2cc(Cl)ccc23)cc1C nan
1482113 40770 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.7 COCc1cc(O)nc2cc(NC(=O)c3cccc(OC)c3)c(C)cc12 nan
CHEMBL1485213 40770 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.7 COCc1cc(O)nc2cc(NC(=O)c3cccc(OC)c3)c(C)cc12 nan
848452 40806 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 4 2.9 COC(=O)c1ccc2ccn(CC(=O)NC3CCCCC3)c2c1 nan
CHEMBL1485568 40806 11 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 4 2.9 COC(=O)c1ccc2ccn(CC(=O)NC3CCCCC3)c2c1 nan
6491858 40927 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 7 3.4 COc1cccc(NC(=O)CSc2nc(O)c3c(C)csc3n2)c1 nan
CHEMBL1486601 40927 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 7 3.4 COc1cccc(NC(=O)CSc2nc(O)c3c(C)csc3n2)c1 nan
12005495 40962 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 2 4 4.0 Cc1cccc(C)c1NC(=O)C(NS(=O)(=O)c1cccs1)c1ccccc1 nan
CHEMBL1486971 40962 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 2 4 4.0 Cc1cccc(C)c1NC(=O)C(NS(=O)(=O)c1cccs1)c1ccccc1 nan
2007999 41033 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 6 3.4 CC(C)c1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
CHEMBL1487512 41033 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 6 3.4 CC(C)c1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
1604294 41060 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 4 5.9 Cc1ccc(OCCCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
CHEMBL1487726 41060 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 0 4 5.9 Cc1ccc(OCCCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
3847044 41226 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 4.1 COC(=O)CSc1nc2sc3c(c2c(=O)n1-c1ccc(C)cc1)CC(C(C)C)OC3 nan
CHEMBL1488882 41226 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 8 4.1 COC(=O)CSc1nc2sc3c(c2c(=O)n1-c1ccc(C)cc1)CC(C(C)C)OC3 nan
3531068 41295 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 5 1 8 4.5 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc3nc(-c4ccc(C)cc4)cc(C(F)(F)F)n3n2)c1 nan
CHEMBL1489426 41295 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 5 1 8 4.5 COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc3nc(-c4ccc(C)cc4)cc(C(F)(F)F)n3n2)c1 nan
3149408 41381 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 6 8 -1.2 Cc1ccc(C2=NNC(C(O)C(O)C(O)C(O)CO)S2)cc1 nan
CHEMBL1490120 41381 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 6 8 -1.2 Cc1ccc(C2=NNC(C(O)C(O)C(O)C(O)CO)S2)cc1 nan
15996835 41449 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 6 3.9 COc1cc2nc(S)nc(NCCc3ccc(C)cc3)c2cc1OC nan
CHEMBL1490579 41449 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 2 6 3.9 COc1cc2nc(S)nc(NCCc3ccc(C)cc3)c2cc1OC nan
5216415 41487 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 5.2 COc1cccc2cc(-c3nc(-c4ccc(Cl)cc4)cs3)c(=O)oc12 nan
CHEMBL1490839 41487 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 0 5 5.2 COc1cccc2cc(-c3nc(-c4ccc(Cl)cc4)cs3)c(=O)oc12 nan
16022523 41546 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 7 2.3 Cn1cnc2c(=O)oc3ccc(S(=O)(=O)N4CCN(c5ccccc5F)CC4)cc3c21 nan
CHEMBL1491216 41546 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 3 0 7 2.3 Cn1cnc2c(=O)oc3ccc(S(=O)(=O)N4CCN(c5ccccc5F)CC4)cc3c21 nan
16034710 41774 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1492881 41774 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 6 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3cccc(Cl)c3)cn(CC(=O)NCc3ccccc3)c2n1 nan
1319924 41803 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 0 6 4.8 CCCS(=O)(=O)c1c(S(=O)(=O)CCC)c2cc(CC)ccn2c1C(=O)c1ccc(Cl)cc1 nan
CHEMBL1493213 41803 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 9 0 6 4.8 CCCS(=O)(=O)c1c(S(=O)(=O)CCC)c2cc(CC)ccn2c1C(=O)c1ccc(Cl)cc1 nan
16423380 41819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
7205024 41819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
CHEMBL1493339 41819 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 7 2.9 COc1ccc(-c2cc3ccc(O)c(CN4CCN(C)CC4)c3oc2=O)cc1OC nan
6823777 41845 6 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 8 3 6 3.3 Cc1ccc(-n2c([S-])c(C(=O)Nc3ccc(OC(F)F)cc3)[n+]3ccc(C(=O)NCCO)cc23)cc1C nan
CHEMBL1493546 41845 6 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 526 8 3 6 3.3 Cc1ccc(-n2c([S-])c(C(=O)Nc3ccc(OC(F)F)cc3)[n+]3ccc(C(=O)NCCO)cc23)cc1C nan
1091748 41849 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.5 O=C(Nc1ccccc1C(=O)Nc1ccc2c(c1)OCO2)c1ccco1 nan
CHEMBL1493592 41849 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.5 O=C(Nc1ccccc1C(=O)Nc1ccc2c(c1)OCO2)c1ccco1 nan
4885142 42238 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.4 CC(=O)c1ccc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)cc1 nan
CHEMBL1497325 42238 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.4 CC(=O)c1ccc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)cc1 nan
665746 42293 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 0 5 3.5 O=C1c2oc3ccccc3c(=O)c2C(c2cccnc2)N1Cc1ccco1 nan
CHEMBL1497863 42293 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 0 5 3.5 O=C1c2oc3ccccc3c(=O)c2C(c2cccnc2)N1Cc1ccco1 nan
1478337 42322 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 2 1 4 5.2 Cc1ccc2oc3nc(C)c(C(=O)Nc4cccc(C(F)(F)F)c4)cc3c(=O)c2c1 nan
CHEMBL1498149 42322 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 2 1 4 5.2 Cc1ccc2oc3nc(C)c(C(=O)Nc4cccc(C(F)(F)F)c4)cc3c(=O)c2c1 nan
1877175 42411 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOc1ccc(C(=O)Nc2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1498972 42411 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOc1ccc(C(=O)Nc2nc(C)c(C(=O)OC)s2)cc1 nan
663555 42658 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1cccc(C(=O)OCc2cc3ccccc3nc2O)c1 nan
CHEMBL1501108 42658 10 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1cccc(C(=O)OCc2cc3ccccc3nc2O)c1 nan
1482342 42839 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 2 1 7 2.2 CSc1nc2ncc(-c3ccsc3)c(N)n2n1 nan
CHEMBL1502638 42839 24 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 2 1 7 2.2 CSc1nc2ncc(-c3ccsc3)c(N)n2n1 nan
6624089 43114 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 4 3.3 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccc(Cl)cc1 nan
CHEMBL1505154 43114 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 5 1 4 3.3 O=C(Cn1c(=O)c2cccn2c2ccccc21)NCCc1ccc(Cl)cc1 nan
1488509 43142 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 3 1 4 1.9 O=C(Nc1ccnc(-c2ccncc2)n1)C1CC1 nan
CHEMBL1505422 43142 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 240 3 1 4 1.9 O=C(Nc1ccnc(-c2ccncc2)n1)C1CC1 nan
8484069 43322 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 8 3.3 CC(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)c3ccco3)s2)cc1 nan
CHEMBL1506911 43322 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 7 2 8 3.3 CC(=O)c1ccc(NC(=O)CSc2nnc(NC(=O)c3ccco3)s2)cc1 nan
2880344 43367 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 6 4.7 COc1ccc(CC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)cc1OC nan
CHEMBL1507312 43367 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 6 4.7 COc1ccc(CC(=O)Nc2ccc(-c3nc4cc(C)ccc4o3)c(O)c2)cc1OC nan
1440345 43456 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 3.2 Cc1cc2cc3c(cc2nc1SCC(=O)O)CCC3 nan
CHEMBL1508003 43456 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 3.2 Cc1cc2cc3c(cc2nc1SCC(=O)O)CCC3 nan
4435004 43645 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 4 1 3 3.8 CCCn1c(NC(=O)c2ccc(F)cc2)nc2ccccc21 nan
CHEMBL1509719 43645 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 4 1 3 3.8 CCCn1c(NC(=O)c2ccc(F)cc2)nc2ccccc21 nan
2676980 43667 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 2.6 O=C(Cn1cnc2ccccc2c1=O)Nc1nc2ccccc2s1 nan
CHEMBL1509918 43667 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 6 2.6 O=C(Cn1cnc2ccccc2c1=O)Nc1nc2ccccc2s1 nan
2402709 43717 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 2 7 3.0 NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)cc1 nan
CHEMBL1510422 43717 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 2 7 3.0 NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)cc1 nan
16024491 43926 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 7 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
CHEMBL1512438 43926 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 7 3.3 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc4c(c3)OCCO4)c2n1 nan
7184798 43934 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 7 3.5 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
CHEMBL1512523 43934 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 7 3.5 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
16025847 43952 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.4 Cc1cccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)c1 nan
CHEMBL1512717 43952 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 2.4 Cc1cccc(CNC(=O)c2cnc3sc(N4CCCCC4)nn3c2=O)c1 nan
16026525 43953 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.6 CCc1ccccc1NC(=O)C(C)n1c(=O)cc(C)c2c(C)nn(-c3ccccc3)c21 nan
CHEMBL1512723 43953 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 4.6 CCc1ccccc1NC(=O)C(C)n1c(=O)cc(C)c2c(C)nn(-c3ccccc3)c21 nan
16026338 43955 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 5 4.7 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4cc(Cl)ccc4C)c32)cc1 nan
CHEMBL1512750 43955 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 5 4.7 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)Nc4cc(Cl)ccc4C)c32)cc1 nan
7066893 43975 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 2 6 4.8 COc1cc(-c2nc3sccn3c2Nc2cccc(C)c2)ccc1O nan
CHEMBL1513064 43975 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 4 2 6 4.8 COc1cc(-c2nc3sccn3c2Nc2cccc(C)c2)ccc1O nan
16025357 43985 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 6 1 6 5.8 Cc1ccc(CN2c3ccccc3-c3nc(SCC(=O)Nc4c(C)cc(C)cc4C)ncc3S2(=O)=O)cc1 nan
CHEMBL1513190 43985 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 544 6 1 6 5.8 Cc1ccc(CN2c3ccccc3-c3nc(SCC(=O)Nc4c(C)cc(C)cc4C)ncc3S2(=O)=O)cc1 nan
16010879 44013 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1cc2nc(NCCc3cccc(C)c3)n3nc(-c4ccccc4)nc3c2cc1OC nan
CHEMBL1513631 44013 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1cc2nc(NCCc3cccc(C)c3)n3nc(-c4ccccc4)nc3c2cc1OC nan
2947326 44040 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 6 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nc3c(C)c(Br)cnc3[nH]2)cc1 nan
CHEMBL1514184 44040 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 2 6 3.9 CCOC(=O)c1ccc(NC(=O)CSc2nc3c(C)c(Br)cnc3[nH]2)cc1 nan
15988389 44077 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 3 5.3 O=C(NCCc1ccccc1)c1cc(-c2ccccc2)nc2n[nH]c(-c3ccccc3)c12 nan
CHEMBL1514741 44077 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 3 5.3 O=C(NCCc1ccccc1)c1cc(-c2ccccc2)nc2n[nH]c(-c3ccccc3)c12 nan
16027439 44111 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n12 nan
CHEMBL1515224 44111 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n12 nan
3324743 44115 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 4 5.2 CCc1ccc(OCC(=O)Nc2c(C(=O)c3ccccc3)oc3ccccc23)cc1 nan
CHEMBL1515282 44115 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 7 1 4 5.2 CCc1ccc(OCC(=O)Nc2c(C(=O)c3ccccc3)oc3ccccc23)cc1 nan
1035668 44161 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 5 5.7 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1 nan
CHEMBL1515955 44161 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 1 5 5.7 Cc1cccc(NC(=O)CSc2nc(-c3cccs3)cc(C(F)(F)F)c2C#N)c1 nan
16009680 44179 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 4 4.6 Cc1ccc(S(=O)(=O)c2cn(Cc3ccc(F)cc3)c3cc(F)c(F)cc3c2=O)cc1 nan
CHEMBL1516142 44179 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 4 0 4 4.6 Cc1ccc(S(=O)(=O)c2cn(Cc3ccc(F)cc3)c3cc(F)c(F)cc3c2=O)cc1 nan
1516716 44202 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 3 5 3.7 Nc1c(C(=O)Nc2ccc(C(=O)O)cc2)sc2nc3c(cc12)CCCC3 nan
CHEMBL1516550 44202 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 3 3 5 3.7 Nc1c(C(=O)Nc2ccc(C(=O)O)cc2)sc2nc3c(cc12)CCCC3 nan
15989644 44204 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)N3CCC(C)CC3)c3ccccc3c2=O)c(Br)c1 nan
CHEMBL1516553 44204 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 531 5 1 5 4.1 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)N3CCC(C)CC3)c3ccccc3c2=O)c(Br)c1 nan
16027696 44241 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
CHEMBL1516896 44241 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1cccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)c1 nan
16009847 44299 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 4 0 6 5.1 O=c1c2sc3ccccc3c2n(Cc2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccco1 nan
CHEMBL1517455 44299 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 4 0 6 5.1 O=c1c2sc3ccccc3c2n(Cc2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccco1 nan
16010572 44301 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 4.0 COc1ccc(OC)c(CCNc2nc3ccccc3c3nc(-c4cccnc4)nn23)c1 nan
CHEMBL1517540 44301 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 7 1 8 4.0 COc1ccc(OC)c(CCNc2nc3ccccc3c3nc(-c4cccnc4)nn23)c1 nan
1073734 44309 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1C nan
CHEMBL1517640 44309 19 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 3 1 5 3.6 Cc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1C nan
15990463 44380 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 8 2 6 4.6 Cc1cccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccc(F)cc4)C(=O)N23)c1 nan
CHEMBL1518319 44380 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 543 8 2 6 4.6 Cc1cccc(NC(=O)CSC2=Nc3ccccc3C3=NC(CCC(=O)NCc4ccc(F)cc4)C(=O)N23)c1 nan
890719 44432 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 0.9 CCN1C(=O)/C(=C\NCc2ccccc2)C(=O)NC1=S nan
CHEMBL1518771 44432 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 0.9 CCN1C(=O)/C(=C\NCc2ccccc2)C(=O)NC1=S nan
4457184 44453 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 2 7 2.2 N#Cc1c(N2CCCCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
CHEMBL1518944 44453 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 2 7 2.2 N#Cc1c(N2CCCCC2)nc(N)c2c(N)nc3c(c12)CC(CCl)O3 nan
16013971 44483 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 0 7 3.7 Cc1nnc(N2CCN(c3ccc(Cl)cc3)CC2)c2c1nnn2Cc1ccc(F)cc1 nan
CHEMBL1519203 44483 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 4 0 7 3.7 Cc1nnc(N2CCN(c3ccc(Cl)cc3)CC2)c2c1nnn2Cc1ccc(F)cc1 nan
1557528 44503 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 8 0 5 5.1 Cc1ccc(OCCOCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
CHEMBL1519353 44503 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 8 0 5 5.1 Cc1ccc(OCCOCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)cc1 nan
2158290 44537 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 9 0 9 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CCCOC)/c1=N/C(=O)C(C)(C)Oc1ccc(Cl)cc1 nan
CHEMBL1519687 44537 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 9 0 9 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CCCOC)/c1=N/C(=O)C(C)(C)Oc1ccc(Cl)cc1 nan
4379652 44678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 10 1.1 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3cccs3)nc2n(C)c1=O nan
CHEMBL1520875 44678 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 10 1.1 Cn1c(=O)c2c(SCC(=O)NCC3CCCO3)nc(-c3cccs3)nc2n(C)c1=O nan
5925852 44724 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 10 3.2 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
CHEMBL1521267 44724 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 10 3.2 COC(=O)c1ccc(C2C(C(=O)c3ccc4c(c3)OCCO4)=C(O)C(=O)N2c2nnc(C)s2)cc1 nan
16018871 44760 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.8 COc1ccc(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1521570 44760 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.8 COc1ccc(CNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1 nan
17252948 44862 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 5 3.9 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1C nan
CHEMBL1522534 44862 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 3 1 5 3.9 Cc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1C nan
16009486 44899 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 9 3.9 COc1cc(C(=O)Nc2ccccc2OCc2cc(=O)n3c(C)csc3n2)cc(OC)c1OC nan
CHEMBL1522858 44899 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 8 1 9 3.9 COc1cc(C(=O)Nc2ccccc2OCc2cc(=O)n3c(C)csc3n2)cc(OC)c1OC nan
932437 44929 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.9 Cc1ccc(-c2nnc3c4ccccc4c(-c4ccccc4)nn23)cc1 nan
CHEMBL1523117 44929 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.9 Cc1ccc(-c2nnc3c4ccccc4c(-c4ccccc4)nn23)cc1 nan
2084813 44977 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(F)ccc2C)c1C nan
CHEMBL1523555 44977 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(F)ccc2C)c1C nan
663733 45020 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 8 3.1 Cc1nc2c(sc3nc4c(cc32)COC(C)(C)C4)c(=O)n1CC(=O)NCc1ccco1 nan
CHEMBL1523984 45020 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 4 1 8 3.1 Cc1nc2c(sc3nc4c(cc32)COC(C)(C)C4)c(=O)n1CC(=O)NCc1ccco1 nan
16027443 45125 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3ccccc3NC(=O)c3ccccc3Cl)cc(=O)n12 nan
CHEMBL1525043 45125 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 7 4.3 Cc1csc2nc(COC(=O)c3ccccc3NC(=O)c3ccccc3Cl)cc(=O)n12 nan
1299413 45216 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 5 3.1 C=CCn1c(SCC(=O)NC2CCCCC2)nc2ccccc2c1=O nan
CHEMBL1525864 45216 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 5 3.1 C=CCn1c(SCC(=O)NC2CCCCC2)nc2ccccc2c1=O nan
4174172 45376 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 7 0 6 4.9 COc1cc2c(cc1OC)C(COc1ccc3c(C)cc(=O)oc3c1)N(C(=O)Cc1ccccc1)CC2 nan
CHEMBL1527205 45376 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 7 0 6 4.9 COc1cc2c(cc1OC)C(COc1ccc3c(C)cc(=O)oc3c1)N(C(=O)Cc1ccccc1)CC2 nan
757005 45655 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 8 2 5 2.7 CCCc1cc(C(=O)OC)c(NC(=O)CCCC(=O)O)s1 nan
CHEMBL1529664 45655 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 8 2 5 2.7 CCCc1cc(C(=O)OC)c(NC(=O)CCCC(=O)O)s1 nan
4067774 45759 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 1 4 6.0 CCCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(C)cc3)oc3ccccc23)cc1 nan
CHEMBL1530590 45759 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 7 1 4 6.0 CCCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(C)cc3)oc3ccccc23)cc1 nan
3420293 45898 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 7 2.9 Cc1ccc(NC(=O)c2sc3ncn(CC(=O)N4CCOCC4)c(=O)c3c2C)c(Br)c1 nan
CHEMBL1531811 45898 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 4 1 7 2.9 Cc1ccc(NC(=O)c2sc3ncn(CC(=O)N4CCOCC4)c(=O)c3c2C)c(Br)c1 nan
821799 45924 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.1 CSc1nc2ccc(Br)cn2c(=O)c1C#N nan
CHEMBL1532047 45924 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.1 CSc1nc2ccc(Br)cn2c(=O)c1C#N nan
1475615 45953 18 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 6 5.0 O=C(Nc1cc2c(=O)n(-c3ccc(Oc4ccccc4)cc3)ccc2oc1=O)c1ccccc1 nan
CHEMBL1532311 45953 18 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 6 5.0 O=C(Nc1cc2c(=O)n(-c3ccc(Oc4ccccc4)cc3)ccc2oc1=O)c1ccccc1 nan
15989915 45997 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 5 4.6 COc1ccc(C2CC(=O)c3c([nH]c(C(=O)OCc4ccccc4)c3C)C2)cc1OC nan
CHEMBL1532686 45997 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 1 5 4.6 COc1ccc(C2CC(=O)c3c([nH]c(C(=O)OCc4ccccc4)c3C)C2)cc1OC nan
656128 46026 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 0 6 2.8 CCOc1ccc2cc(C#N)c(SCC(=O)OC)nc2c1 nan
CHEMBL1532931 46026 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 5 0 6 2.8 CCOc1ccc2cc(C#N)c(SCC(=O)OC)nc2c1 nan
3137936 46155 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 5 3.4 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2C)c1C nan
CHEMBL1534032 46155 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 5 3.4 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2C)c1C nan
16011802 46205 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 3.4 COc1ccc(C(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1OC nan
CHEMBL1534572 46205 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 3.4 COc1ccc(C(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1OC nan
3410008 46225 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 2.8 CCOc1ccc(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)cc1 nan
CHEMBL1534800 46225 9 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 2 5 2.8 CCOc1ccc(N/C=C2/C(=O)NC(=S)N(Cc3ccccc3)C2=O)cc1 nan
5949916 46267 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.0 Cc1[nH]c2nc(SCC(=O)c3ccccc3)nc-2cc1Br nan
CHEMBL1535293 46267 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 1 4 4.0 Cc1[nH]c2nc(SCC(=O)c3ccccc3)nc-2cc1Br nan
2820834 46278 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 5.6 CSc1sc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2C)c2c1C=CCC2 nan
CHEMBL1535400 46278 5 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 7 5.6 CSc1sc(-c2nnc(SCC(=O)Nc3ccc(Cl)cc3)n2C)c2c1C=CCC2 nan
16019886 46345 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 3.2 Cc1cccc(NC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1C nan
CHEMBL1536151 46345 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 3.2 Cc1cccc(NC(=O)CN2C(=O)CSc3ccc(S(=O)(=O)N4CCCC4)cc32)c1C nan
891752 46405 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.6 COc1cc(Cl)c(C)cc1NC(=O)c1ccc2c(c1)OCO2 nan
CHEMBL1536712 46405 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 1 4 3.6 COc1cc(Cl)c(C)cc1NC(=O)c1ccc2c(c1)OCO2 nan
664078 46699 2 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 1 4 3.3 COc1cccc(OCc2nc3cc(Br)c[nH]c-3n2)c1 nan
CHEMBL1539150 46699 2 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 1 4 3.3 COc1cccc(OCc2nc3cc(Br)c[nH]c-3n2)c1 nan
841141 47050 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 5 2.2 COC(=O)c1c(NC(=O)c2ccccc2)sc(C(N)=O)c1C nan
CHEMBL1542119 47050 10 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 4 2 5 2.2 COC(=O)c1c(NC(=O)c2ccccc2)sc(C(N)=O)c1C nan
664933 47212 11 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
CHEMBL1543543 47212 11 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2ccc(F)cc2)c2oc3ccccc3c2n1 nan
3240821 47284 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 8 2.9 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(C(=O)c2ccco2)CC1 nan
CHEMBL1544051 47284 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 8 2.9 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(C(=O)c2ccco2)CC1 nan
1861702 47341 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 8 2.7 CC(C)OC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
CHEMBL1544436 47341 8 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 8 2.7 CC(C)OC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
3164596 47470 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 2.7 COc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 nan
CHEMBL1545409 47470 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 4 1 4 2.7 COc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 nan
4340721 47524 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 4.0 COc1ccc2cc(C#N)c(Nc3cccc(F)c3)nc2c1 nan
CHEMBL1545865 47524 8 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 4.0 COc1ccc2cc(C#N)c(Nc3cccc(F)c3)nc2c1 nan
2106365 47527 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 5 4.1 Oc1nc(-c2cccnc2)nc2sc(-c3ccccc3)cc12 nan
CHEMBL1545901 47527 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 5 4.1 Oc1nc(-c2cccnc2)nc2sc(-c3ccccc3)cc12 nan
902245 47674 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 1 3 4.9 CCc1cc2cc(C(=O)Nc3ccc(F)cc3)sc2s1 nan
CHEMBL1547204 47674 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 1 3 4.9 CCc1cc2cc(C(=O)Nc3ccc(F)cc3)sc2s1 nan
1088622 47704 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 9 1.2 CCOc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1OC nan
CHEMBL1547487 47704 14 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 1 9 1.2 CCOc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1OC nan
2801256 47843 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 1 5 2.4 Cc1nc(-c2cc(C#N)c(O)nc2C)cs1 nan
CHEMBL1548830 47843 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 231 1 1 5 2.4 Cc1nc(-c2cc(C#N)c(O)nc2C)cs1 nan
4601866 47954 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 10 3 6 3.4 NS(=O)(=O)c1ccc(CCNC(=O)CCCCCn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
CHEMBL1549770 47954 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 552 10 3 6 3.4 NS(=O)(=O)c1ccc(CCNC(=O)CCCCCn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 nan
2731089 48002 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 2 7 2.6 COc1ccc(CCNC(=S)NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC nan
CHEMBL1550121 48002 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 2 7 2.6 COc1ccc(CCNC(=S)NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC nan
5122884 48034 5 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 2.8 COc1ccc2cc(CCN3C(=O)c4ccccc4C3=O)c(O)nc2c1 nan
CHEMBL1550382 48034 5 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 5 2.8 COc1ccc2cc(CCN3C(=O)c4ccccc4C3=O)c(O)nc2c1 nan
1490541 48040 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 3 4.2 Cc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
CHEMBL1550435 48040 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 1 3 4.2 Cc1ccccc1CNc1ncnc2cc(Cl)ccc12 nan
15944825 48102 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 5 4.2 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1550942 48102 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 5 1 5 4.2 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
15988480 48120 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 6 2.4 COC(=O)c1cc(Cl)ccc1NC(=O)Cn1c(C)cc(C)c(C#N)c1=O nan
CHEMBL1551156 48120 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 6 2.4 COC(=O)c1cc(Cl)ccc1NC(=O)Cn1c(C)cc(C)c(C#N)c1=O nan
16025269 48123 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 2 5 4.7 COC(=O)c1c(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c2ccc(Cl)cc2c1=O nan
CHEMBL1551199 48123 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 2 5 4.7 COC(=O)c1c(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]c2ccc(Cl)cc2c1=O nan
16009432 48138 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 6 3.9 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)c1 nan
CHEMBL1551357 48138 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 6 3.9 Cc1cccc(C(=O)Nc2ccc(OCc3cc(=O)n4ccsc4n3)cc2)c1 nan
3151519 48141 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 8 3 8 1.4 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccccc4)c(=N)n(CCOCCO)c3nc12 nan
CHEMBL1551451 48141 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 8 3 8 1.4 Cc1cccn2c(=O)c3cc(C(=O)NCc4ccccc4)c(=N)n(CCOCCO)c3nc12 nan
16007408 48147 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 2 3 3.7 Cc1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1F nan
CHEMBL1551538 48147 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 2 3 3.7 Cc1ccc(NC(=O)c2cc3c(=O)[nH]c4ccccc4c3n2C)cc1F nan
16021062 48157 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 6 3.5 COC(=O)c1ccccc1NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
CHEMBL1551793 48157 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 3 1 6 3.5 COC(=O)c1ccccc1NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 nan
1189625 48164 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)cc1 nan
CHEMBL1551857 48164 17 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1ccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)cc1 nan
16008906 48171 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1cccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1551951 48171 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1cccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
16011042 48181 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 2 3 4.8 O=C(Nc1ccc(F)cc1)c1ccc2c(c1)NC(=O)c1ccccc1S2 nan
CHEMBL1552027 48181 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 2 3 4.8 O=C(Nc1ccc(F)cc1)c1ccc2c(c1)NC(=O)c1ccccc1S2 nan
4412264 48182 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 0 8 4.5 CCOC(=O)CSc1nc2c(sc3cccc(F)c32)c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1552040 48182 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 7 0 8 4.5 CCOC(=O)CSc1nc2c(sc3cccc(F)c32)c(=O)n1Cc1ccc(OC)cc1 nan
1187153 48184 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 3.5 CCOC(=O)c1cnc2c(Cl)c(Cl)ccc2c1NCCN1CCOCC1 nan
CHEMBL1552062 48184 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 6 3.5 CCOC(=O)c1cnc2c(Cl)c(Cl)ccc2c1NCCN1CCOCC1 nan
16027700 48206 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1C nan
CHEMBL1552279 48206 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 7 1 8 3.7 Cc1ccc(OCC(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1C nan
16032167 48224 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 8 3.5 Cn1c(SCC(=O)Nc2nc3ccccc3s2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
CHEMBL1552642 48224 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 2 8 3.5 Cn1c(SCC(=O)Nc2nc3ccccc3s2)ncc(C(=O)Nc2ccc(F)cc2)c1=O nan
16024489 48242 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 5 4.5 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc(C)c(Cl)c3)c2n1 nan
CHEMBL1552935 48242 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 5 4.5 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccc(C)c(Cl)c3)c2n1 nan
16030793 48243 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 5.2 COc1ccccc1-c1cc(NC(=O)COc2ccccc2Cl)n(-c2ccccc2)n1 nan
CHEMBL1552946 48243 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 7 1 5 5.2 COc1ccccc1-c1cc(NC(=O)COc2ccccc2Cl)n(-c2ccccc2)n1 nan
16020265 48250 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 6 2.5 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(CC(N)=O)c2=O)cc1 nan
CHEMBL1552986 48250 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 2 6 2.5 Cc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3n(CC(N)=O)c2=O)cc1 nan
16024860 48271 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 4 3.9 O=S(=O)(c1ccc2nc(Nc3ccc(F)cc3)ccc2c1)N1CCCC1 nan
CHEMBL1553226 48271 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 4 1 4 3.9 O=S(=O)(c1ccc2nc(Nc3ccc(F)cc3)ccc2c1)N1CCCC1 nan
16014611 48280 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 5 3.1 CSc1ccc(NC(=O)C2CCN(c3ncccn3)CC2)cc1 nan
CHEMBL1553334 48280 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 5 3.1 CSc1ccc(NC(=O)C2CCN(c3ncccn3)CC2)cc1 nan
16018242 48296 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1OC nan
CHEMBL1553551 48296 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 6 1 6 5.5 COc1ccc(NC(=O)c2oc3c(c2C)-c2nn(Cc4ccccc4Cl)cc2CC3)cc1OC nan
16020219 48299 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 4 4.2 Cn1c(=O)c2cc(C(=O)NC3CCCCCC3)sc2c2ccccc21 nan
CHEMBL1553584 48299 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 4 4.2 Cn1c(=O)c2cc(C(=O)NC3CCCCCC3)sc2c2ccccc21 nan
3158758 48301 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 4.2 COc1cc(OC)c(C2Nc3c(C)cccc3-c3cc(C)nn32)cc1OC nan
CHEMBL1553632 48301 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 4 1 6 4.2 COc1cc(OC)c(C2Nc3c(C)cccc3-c3cc(C)nn32)cc1OC nan
15989000 48304 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2ccccc2F)c1=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1553743 48304 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 1 8 2.8 O=C(CCn1c(=O)c2sccc2n(Cc2ccccc2F)c1=O)NCc1ccc2c(c1)OCO2 nan
2580267 48311 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 2.9 Cc1cc(C)cc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 nan
CHEMBL1553826 48311 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 2.9 Cc1cc(C)cc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 nan
16033854 48315 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 8 3.1 COC(=O)c1ccc2c(=O)n3nc(Nc4ccc(F)cc4F)sc3nc2c1 nan
CHEMBL1553893 48315 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 8 3.1 COC(=O)c1ccc2c(=O)n3nc(Nc4ccc(F)cc4F)sc3nc2c1 nan
16030113 48330 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1cccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)c1 nan
CHEMBL1554129 48330 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 6 3.5 Cc1cccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)c1 nan
4361698 48349 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1cccc(C(F)(F)F)c1 nan
CHEMBL1554379 48349 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 540 5 0 8 3.8 CCOC(=O)c1cc2c(=O)n3ccccc3nc2n(CC2CCCO2)/c1=N\C(=O)c1cccc(C(F)(F)F)c1 nan
16282512 48351 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 5 3.2 Cc1ccc(NC(=O)CN(C)C(=O)COc2ncnc3ccc(Br)cc23)cc1 nan
CHEMBL1554437 48351 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 6 1 5 3.2 Cc1ccc(NC(=O)CN(C)C(=O)COc2ncnc3ccc(Br)cc23)cc1 nan
16009851 48354 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.2 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3sc4ccccc4c32)c1 nan
CHEMBL1554474 48354 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 7 4.2 COc1cccc(NC(=O)Cn2c(=O)n(Cc3ccc(F)cc3)c(=O)c3sc4ccccc4c32)c1 nan
16011879 48355 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 2 4.1 Cc1ccc(CNC(=O)Cc2csc3ccccc23)cc1 nan
CHEMBL1554476 48355 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 4 1 2 4.1 Cc1ccc(CNC(=O)Cc2csc3ccccc23)cc1 nan
15988910 48358 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 0 10 2.6 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3cc(=O)n4c(C)cccc4n3)c2=O)c1 nan
CHEMBL1554524 48358 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 0 10 2.6 COc1cc(OC)cc(-n2c(=O)c3sccc3n(Cc3cc(=O)n4c(C)cccc4n3)c2=O)c1 nan
16009798 48359 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 4.8 Fc1cccc(-c2nnn3c2nc(NC2CCCCC2)c2ccccc23)c1 nan
CHEMBL1554525 48359 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 3 1 5 4.8 Fc1cccc(-c2nnn3c2nc(NC2CCCCC2)c2ccccc23)c1 nan
16019045 48360 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 4.0 CCOc1cc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)ccc1OC nan
CHEMBL1554576 48360 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 8 1 7 4.0 CCOc1cc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)ccc1OC nan
16010240 48374 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 3 5.3 CC(C)c1ccc(NC(=O)c2cc3sc(Cl)cc3n2C)cc1 nan
CHEMBL1554758 48374 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 3 5.3 CC(C)c1ccc(NC(=O)c2cc3sc(Cl)cc3n2C)cc1 nan
16016717 48405 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 3 6.0 CCc1ccccc1NC(=O)Nc1ccc2c(c1)N(CC)C(=O)c1ccccc1S2 nan
CHEMBL1555228 48405 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 4 2 3 6.0 CCc1ccccc1NC(=O)Nc1ccc2c(c1)N(CC)C(=O)c1ccccc1S2 nan
15999699 48407 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.7 CCCCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1555241 48407 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.7 CCCCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
16024527 48487 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.2 COc1ccc(C(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1556147 48487 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 6 4.2 COc1ccc(C(=O)c2cn(CC(=O)Nc3cc(C)ccc3C)c3nc(C)ccc3c2=O)cc1 nan
884827 48488 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 1 5 3.8 CCOc1ccc(Nc2nc3ccccc3c(=O)s2)cc1 nan
CHEMBL1556149 48488 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 4 1 5 3.8 CCOc1ccc(Nc2nc3ccccc3c(=O)s2)cc1 nan
1299811 48509 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 0 8 3.4 COC(=O)CSc1ncnc2c1sc1nc3c(cc12)COC(C)(C)C3 nan
CHEMBL1556306 48509 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 0 8 3.4 COC(=O)CSc1ncnc2c1sc1nc3c(cc12)COC(C)(C)C3 nan
1297627 48539 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 3 4.1 CC(=O)c1ccc(NC(=S)N2CCN(c3cccc(Cl)c3)CC2)cc1 nan
CHEMBL1556657 48539 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 3 1 3 4.1 CC(=O)c1ccc(NC(=S)N2CCN(c3cccc(Cl)c3)CC2)cc1 nan
1262055 48541 7 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 5.3 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1-c1cc2cc(Br)ccc2o1 nan
CHEMBL1556666 48541 7 None -2 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 6 5.3 CCn1c(SCC(=O)Nc2cccc(F)c2)nnc1-c1cc2cc(Br)ccc2o1 nan
2769090 48701 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 0 5 2.8 CC(=O)c1cc(C#N)c(N2CCN(c3ccccc3)CC2)nc1C nan
CHEMBL1558006 48701 25 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 0 5 2.8 CC(=O)c1cc(C#N)c(N2CCN(c3ccccc3)CC2)nc1C nan
16015862 48872 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 5.7 Cc1ccc(SCC(=O)Nc2ccc3oc(-c4ccc(F)cc4)nc3c2)cc1 nan
CHEMBL1559463 48872 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 4 5.7 Cc1ccc(SCC(=O)Nc2ccc3oc(-c4ccc(F)cc4)nc3c2)cc1 nan
3208119 48898 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2ccc(C)c(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1559714 48898 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 4.4 CCc1cc2ccc(C)c(C)c2nc1SCC(=O)Nc1cc(C)on1 nan
16286863 49072 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 2 6 2.7 CC(OC(=O)c1cc(Br)ccc1O)C(=O)NCc1ccc2c(c1)OCO2 nan
CHEMBL1561413 49072 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 2 6 2.7 CC(OC(=O)c1cc(Br)ccc1O)C(=O)NCc1ccc2c(c1)OCO2 nan
24686491 49230 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccc(C)cn1 nan
CHEMBL1562813 49230 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 5 1 5 3.2 COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)Nc1ccc(C)cn1 nan
135884418 49246 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 7 3.9 COc1cc2ccccc2cc1C(=O)OCc1nc(O)c2sccc2n1 nan
CHEMBL1562918 49246 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 7 3.9 COc1cc2ccccc2cc1C(=O)OCc1nc(O)c2sccc2n1 nan
664089 49296 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2cccc(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1563407 49296 8 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 4 1 5 4.6 Cc1nc(SCC(=O)Nc2cccc(F)c2)c2oc3ccccc3c2n1 nan
16008603 49297 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 1.5 COc1ccc(CNC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1563417 49297 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 7 1.5 COc1ccc(CNC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
16025580 49345 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 4 1 6 4.6 Cc1cc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)c(C)c1 nan
CHEMBL1563792 49345 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 4 1 6 4.6 Cc1cc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)c(C)c1 nan
654285 49462 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 6 1.7 N#Cc1cc2cc3c(cc2nc1N1CCOCC1)OCO3 nan
CHEMBL1564877 49462 1 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 1 0 6 1.7 N#Cc1cc2cc3c(cc2nc1N1CCOCC1)OCO3 nan
4282255 49564 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 1 6 2.6 COc1cc([N+](=O)[O-])cc2sc(NC(=O)C3CC3)nc12 nan
CHEMBL1565614 49564 12 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 4 1 6 2.6 COc1cc([N+](=O)[O-])cc2sc(NC(=O)C3CC3)nc12 nan
151922 49838 64 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 12 1 1 5.2 O=C(O)CCCCCCCCCCCc1ccccc1 nan
CHEMBL1567811 49838 64 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 276 12 1 1 5.2 O=C(O)CCCCCCCCCCCc1ccccc1 nan
4289114 49961 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 6.0 Cc1ccc(C(=O)c2oc3ccccc3c2NC(=O)C(C)Oc2ccccc2Cl)cc1 nan
CHEMBL1568822 49961 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 4 6.0 Cc1ccc(C(=O)c2oc3ccccc3c2NC(=O)C(C)Oc2ccccc2Cl)cc1 nan
650090 49992 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 9 2.7 Cn1c(=O)c2c(nc(SCC(=O)c3cccs3)n2Cc2ccc(F)cc2)n(C)c1=O nan
CHEMBL1569069 49992 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 0 9 2.7 Cn1c(=O)c2c(nc(SCC(=O)c3cccs3)n2Cc2ccc(F)cc2)n(C)c1=O nan
1336265 50130 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 2 6 2.5 COC(=O)c1sc(NC(=S)NC(=O)c2ccccc2F)nc1C nan
CHEMBL1570262 50130 7 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 3 2 6 2.5 COC(=O)c1sc(NC(=S)NC(=O)c2ccccc2F)nc1C nan
1834757 50171 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 5 6.7 CCN(CC)c1ccc2cc(-c3nc(-c4ccc(Cl)cc4Cl)cs3)c(=O)oc2c1 nan
CHEMBL1570631 50171 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 5 0 5 6.7 CCN(CC)c1ccc2cc(-c3nc(-c4ccc(Cl)cc4Cl)cs3)c(=O)oc2c1 nan
661116 50249 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 3.2 COc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
CHEMBL1571331 50249 8 None -1 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 8 3.2 COc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
3228933 50309 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 3.5 CCc1nc(SCC(=O)Nc2c(C)nn(C)c2C)c2cnn(-c3ccccc3)c2n1 nan
CHEMBL1571990 50309 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 8 3.5 CCc1nc(SCC(=O)Nc2c(C)nn(C)c2C)c2cnn(-c3ccccc3)c2n1 nan
998563 50319 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 3 5.8 Cc1ccc(NC(=O)c2cc(-c3cccs3)nc3ccccc23)c(C)c1 nan
CHEMBL1572046 50319 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 1 3 5.8 Cc1ccc(NC(=O)c2cc(-c3cccs3)nc3ccccc23)c(C)c1 nan
5038692 50357 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 1.9 O=C(O)C1Cc2ccccc2CN1C(=O)CSc1nnc2ccccn12 nan
CHEMBL1572334 50357 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 1.9 O=C(O)C1Cc2ccccc2CN1C(=O)CSc1nnc2ccccn12 nan
16020271 50631 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 7 1 6 5.1 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3cccc(Cl)c3)c2=O)cc1 nan
CHEMBL1575057 50631 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 539 7 1 6 5.1 COc1ccc(-n2c(=O)c3ccc(C(=O)NCc4ccc(C)cc4)cc3n(Cc3cccc(Cl)c3)c2=O)cc1 nan
1637692 50643 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 4.1 CC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2)nc1C nan
CHEMBL1575283 50643 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 4.1 CC(=O)c1sc(NC(=O)CCCOc2ccc(Cl)cc2)nc1C nan
2446441 50913 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 2 2 4.2 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Br)c1C nan
CHEMBL1577640 50913 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 2 2 4.2 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Br)c1C nan
2868371 50938 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 6 2 7 2.5 CCOc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
CHEMBL1577894 50938 12 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 6 2 7 2.5 CCOc1ccccc1NC(=O)CSc1nc(N)c(C#N)cc1C#N nan
7207360 50942 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 7 3.4 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3ccncc3)nn2)cc1 nan
CHEMBL1577921 50942 9 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 7 3.4 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3ccncc3)nn2)cc1 nan
24891931 51022 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 2 7 0.7 NS(=O)(=O)c1ccc(CCNC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
CHEMBL1578510 51022 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 2 7 0.7 NS(=O)(=O)c1ccc(CCNC(=O)C(=O)c2cn(CC(=O)N3CCOCC3)c3ccccc23)cc1 nan
712274 51060 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 3 5 2.2 NC(=O)c1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 nan
CHEMBL1578798 51060 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 3 5 2.2 NC(=O)c1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 nan
7416477 51211 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 4 3.5 Cc1cccc(C(=O)OCC(=O)c2cccc(Br)c2)c1O nan
CHEMBL1580196 51211 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 4 1 4 3.5 Cc1cccc(C(=O)OCC(=O)c2cccc(Br)c2)c1O nan
16193583 51240 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 10 1 8 3.3 CCCCNC(=O)CSc1nc2ccc(N3CCOCC3)cc2c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1580449 51240 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 10 1 8 3.3 CCCCNC(=O)CSc1nc2ccc(N3CCOCC3)cc2c(=O)n1Cc1ccc(OC)cc1 nan
135421577 51285 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 2 3 2.0 C=CCN1C(=O)/C(=C/c2cc3ccccc3[nH]2)C(=O)NC1=S nan
CHEMBL1580833 51285 3 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 3 2 3 2.0 C=CCN1C(=O)/C(=C/c2cc3ccccc3[nH]2)C(=O)NC1=S nan
652265 51340 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 4.1 O=C(Nc1ccc(Oc2ccccc2)cc1)C1CCN(c2ncccn2)CC1 nan
CHEMBL1581276 51340 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 5 1 5 4.1 O=C(Nc1ccc(Oc2ccccc2)cc1)C1CCN(c2ncccn2)CC1 nan
4455225 51429 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 9 2 5 3.5 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCCc3ccccc3)ccc2c1=O nan
CHEMBL1582016 51429 2 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 9 2 5 3.5 CCOCCCn1c(=S)[nH]c2cc(C(=O)NCCc3ccccc3)ccc2c1=O nan
135693216 51681 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 5 2.9 Cc1cccc(CCNC(=O)Cn2ncc3c4ccccc4nc-3c2O)c1 nan
CHEMBL1584056 51681 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 5 2 5 2.9 Cc1cccc(CCNC(=O)Cn2ncc3c4ccccc4nc-3c2O)c1 nan
3662539 51704 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 1 4 7 3.1 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1c(F)cccc1Cl nan
CHEMBL1584309 51704 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 1 4 7 3.1 N#Cc1c(N)nc2c3c(sc(=N)c2c1N)NC(=O)CC3c1c(F)cccc1Cl nan
24819718 51836 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 2 4.0 O=C(c1cc2ccccc2cc1O)N1CCCC(C(F)(F)F)C1 nan
CHEMBL1585344 51836 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 1 1 2 4.0 O=C(c1cc2ccccc2cc1O)N1CCCC(C(F)(F)F)C1 nan
2112635 51989 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 6 2.9 Cc1nc(NCc2ccc(S(N)(=O)=O)cc2)c2c(C)c(C)sc2n1 nan
CHEMBL1586644 51989 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 2 6 2.9 Cc1nc(NCc2ccc(S(N)(=O)=O)cc2)c2c(C)c(C)sc2n1 nan
135441025 52003 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 2 4 3.7 CCCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
CHEMBL1586724 52003 13 None -3 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 3 2 4 3.7 CCCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
2158327 52045 11 None -17 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccc(F)cc1 nan
CHEMBL1587044 52045 11 None -17 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccc(F)cc1 nan
20876043 52217 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 0.5 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1 nan
CHEMBL1588535 52217 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 8 0.5 COc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)c1 nan
16016041 52368 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 4 4.5 COc1ccc(CC(=O)Nc2nc3c(s2)CC(C(C)(C)C)CC3)cc1 nan
CHEMBL1589883 52368 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 4 4.5 COc1ccc(CC(=O)Nc2nc3c(s2)CC(C(C)(C)C)CC3)cc1 nan
4671465 52393 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 4 3.3 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccc(F)cc3)o2)cc1 nan
CHEMBL1590137 52393 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 6 2 4 3.3 NC(=O)c1ccc(NC(=O)c2ccc(COc3ccc(F)cc3)o2)cc1 nan
16009149 52423 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 3 5.5 Cc1ccc(CNC(=O)CSc2c3c(nc4cc(Cl)ccc24)CCCC3)cc1 nan
CHEMBL1590589 52423 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 1 3 5.5 Cc1ccc(CNC(=O)CSc2c3c(nc4cc(Cl)ccc24)CCCC3)cc1 nan
16026741 52431 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 0 8 2.8 O=C(COc1ccc(Cl)cc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 nan
CHEMBL1590675 52431 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 0 8 2.8 O=C(COc1ccc(Cl)cc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 nan
16025957 52437 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1590760 52437 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 8 1.6 O=C(NCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
16033877 52438 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 8 4.0 O=C(NCc1cccs1)c1ccc2c(=O)n3nc(Nc4ccccc4)sc3nc2c1 nan
CHEMBL1590761 52438 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 5 2 8 4.0 O=C(NCc1cccs1)c1ccc2c(=O)n3nc(Nc4ccccc4)sc3nc2c1 nan
18567961 52455 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 9 2 6 3.3 COc1ccc(C(=O)Nc2nc(CC(=O)NCCc3ccccc3OC)cs2)cc1 nan
CHEMBL1590928 52455 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 9 2 6 3.3 COc1ccc(C(=O)Nc2nc(CC(=O)NCCc3ccccc3OC)cs2)cc1 nan
16021437 52482 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 4 6.6 Cc1cc(Nc2cccc(Cl)c2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 nan
CHEMBL1591314 52482 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 2 4 6.6 Cc1cc(Nc2cccc(Cl)c2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 nan
16030267 52495 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCCC2)cc1 nan
CHEMBL1591398 52495 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 0 4 4.6 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCCC2)cc1 nan
15988978 52496 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 7 3.9 COc1ccc(NC(=O)Cn2c(=O)n(-c3cccc(C(F)(F)F)c3)c(=O)c3sccc32)cc1 nan
CHEMBL1591409 52496 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 1 7 3.9 COc1ccc(NC(=O)Cn2c(=O)n(-c3cccc(C(F)(F)F)c3)c(=O)c3sccc32)cc1 nan
4905426 52499 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.4 COc1ccc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2c1 nan
CHEMBL1591442 52499 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 1 2 3.4 COc1ccc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2c1 nan
15989516 52540 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 9 2 6 4.0 O=C(Cn1c(=O)n(CC2CCC(C(=O)NCCc3ccccc3)CC2)c(=O)c2ccccc21)Nc1ccccc1 nan
CHEMBL1592027 52540 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 9 2 6 4.0 O=C(Cn1c(=O)n(CC2CCC(C(=O)NCCc3ccccc3)CC2)c(=O)c2ccccc21)Nc1ccccc1 nan
15991260 52560 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 7 1.4 CCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
CHEMBL1592271 52560 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 7 1.4 CCn1c(=N)c(C(=O)NCC2CCCO2)cc2c(=O)n3cc(C)ccc3nc21 nan
16027708 52583 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 7 4.7 CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1592618 52583 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 5 1 7 4.7 CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
16027669 52584 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 7 4.9 O=C(Nc1ccccc1C(=O)OCc1cc(=O)n2c3c(sc2n1)CCCC3)c1cccc(Cl)c1 nan
CHEMBL1592645 52584 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 5 1 7 4.9 O=C(Nc1ccccc1C(=O)OCc1cc(=O)n2c3c(sc2n1)CCCC3)c1cccc(Cl)c1 nan
16024581 52595 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 5 3.7 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1 nan
CHEMBL1592799 52595 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 5 3.7 Cc1ccc(CNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1 nan
16020979 52626 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 4.5 COc1cc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc(OC)c1 nan
CHEMBL1593212 52626 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 8 1 7 4.5 COc1cc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc(OC)c1 nan
16012982 52640 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 3 5.7 Cc1cccc(N(Cc2cc3ccccc3nc2O)C(=O)c2cccc(Cl)c2)c1 nan
CHEMBL1593385 52640 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 3 5.7 Cc1cccc(N(Cc2cc3ccccc3nc2O)C(=O)c2cccc(Cl)c2)c1 nan
5143379 52641 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 3 5.0 CC(=O)Nc1cc(C(=O)NCc2ccc(F)cc2)ccc1Sc1ccc(F)cc1 nan
CHEMBL1593424 52641 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 6 2 3 5.0 CC(=O)Nc1cc(C(=O)NCc2ccc(F)cc2)ccc1Sc1ccc(F)cc1 nan
16322180 52657 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 5 3.7 Cc1nc(SC(C)C(=O)NC2(C#N)CCCCC2)c(C#N)c(C)c1C nan
CHEMBL1593705 52657 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 1 5 3.7 Cc1nc(SC(C)C(=O)NC2(C#N)CCCCC2)c(C#N)c(C)c1C nan
16024549 52663 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 4.6 CCOc1ccccc1NC(=O)Cn1cc(C(=O)c2ccc(Cl)cc2)c(=O)c2ccc(C)nc21 nan
CHEMBL1593798 52663 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 6 4.6 CCOc1ccccc1NC(=O)Cn1cc(C(=O)c2ccc(Cl)cc2)c(=O)c2ccc(C)nc21 nan
16019841 52667 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 7 4.1 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3Cl)nnc12 nan
CHEMBL1593835 52667 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 1 7 4.1 CC(C)Cn1c(=O)c2sccc2n2c(CCCC(=O)NCc3ccccc3Cl)nnc12 nan
16026849 52674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.8 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(F)cc4)cc3c2=O)cc1 nan
CHEMBL1593965 52674 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 6 1 5 3.8 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(F)cc4)cc3c2=O)cc1 nan
16024916 52680 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.9 CSc1ccc(CCNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
CHEMBL1594028 52680 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.9 CSc1ccc(CCNC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)cc1 nan
16024610 52690 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3cccc(C)c3C)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1594130 52690 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 6 1 5 4.8 CCc1ccc(C(=O)c2cn(CC(=O)Nc3cccc(C)c3C)c3nc(C)ccc3c2=O)cc1 nan
2140504 52836 20 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 6 3.4 N#Cc1cc2c(nc1SCC(=O)Nc1nccs1)CCCCC2 nan
CHEMBL1595336 52836 20 None -3 3 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 6 3.4 N#Cc1cc2c(nc1SCC(=O)Nc1nccs1)CCCCC2 nan
16024587 52919 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
CHEMBL1596100 52919 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCc3ccccc3)c2n1 nan
865538 52957 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 4.0 Cc1ccc2nc(NCc3ccccc3)c(C#N)cc2c1 nan
CHEMBL1596421 52957 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 273 3 1 3 4.0 Cc1ccc2nc(NCc3ccccc3)c(C#N)cc2c1 nan
16008803 52968 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 5.8 CCOc1ccccc1NC(=O)c1cc2c(Cl)nc3ccccc3c2s1 nan
CHEMBL1596557 52968 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 1 4 5.8 CCOc1ccccc1NC(=O)c1cc2c(Cl)nc3ccccc3c2s1 nan
1191858 52976 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 6 3.8 COc1ccc(-c2cc(=O)c3cc(OCC(=O)OC(C)C)ccc3o2)cc1 nan
CHEMBL1596612 52976 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 6 3.8 COc1ccc(-c2cc(=O)c3cc(OCC(=O)OC(C)C)ccc3o2)cc1 nan
16011437 52980 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NCCc4ccccc4)cc3)nc3cccnc32)cc1 nan
CHEMBL1596645 52980 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 10 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NCCc4ccccc4)cc3)nc3cccnc32)cc1 nan
2110721 52999 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(F)c(F)c2F)c1C nan
CHEMBL1596828 52999 8 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 3 2 2 3.5 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(F)c(F)c2F)c1C nan
15991384 53035 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 4 6.2 COc1c(C)cccc1C(=O)Nc1ccc(-c2nc3ccccc3s2)c(Cl)c1 nan
CHEMBL1597164 53035 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 4 6.2 COc1c(C)cccc1C(=O)Nc1ccc(-c2nc3ccccc3s2)c(Cl)c1 nan
9397360 53213 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 8 3.6 CCc1nnc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)s1 nan
CHEMBL1598832 53213 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 1 8 3.6 CCc1nnc(NC(=O)C2CCN(c3ncnc4sc(C)c(C)c34)CC2)s1 nan
1873710 53235 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 5.3 CCOc1nc(-c2ccc(C)cc2)ccc1-c1noc(-c2ccccc2F)n1 nan
CHEMBL1599008 53235 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 0 5 5.3 CCOc1nc(-c2ccc(C)cc2)ccc1-c1noc(-c2ccccc2F)n1 nan
16016553 53255 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.1 Cc1cc(C)cc(OCC(=O)Nc2nonc2-c2ccc(Br)cc2)c1 nan
CHEMBL1599164 53255 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 1 5 4.1 Cc1cc(C)cc(OCC(=O)Nc2nonc2-c2ccc(Br)cc2)c1 nan
16027417 53275 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 8 4.1 Cc1csc2nc(COC(=O)c3cccc(NC(=O)COc4ccccc4Cl)c3)cc(=O)n12 nan
CHEMBL1599306 53275 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 8 4.1 Cc1csc2nc(COC(=O)c3cccc(NC(=O)COc4ccccc4Cl)c3)cc(=O)n12 nan
5059359 53343 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 2 0 6 4.4 Cn1c(=O)c2c(-c3ccccc3)n3c4ccccc4nc(-c4ccccc4)c3c2n(C)c1=O nan
CHEMBL1599921 53343 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 2 0 6 4.4 Cn1c(=O)c2c(-c3ccccc3)n3c4ccccc4nc(-c4ccccc4)c3c2n(C)c1=O nan
16019821 53424 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1600701 53424 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
16021830 53553 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.4 CSc1ncc(C(=O)Nc2ccc(F)cc2F)c(-c2ccccc2)n1 nan
CHEMBL1602038 53553 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 4 4.4 CSc1ncc(C(=O)Nc2ccc(F)cc2F)c(-c2ccccc2)n1 nan
4197620 53574 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 6 2.7 COc1ccc(Cl)cc1NC(=O)c1cnc2sccn2c1=O nan
CHEMBL1602236 53574 15 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 1 6 2.7 COc1ccc(Cl)cc1NC(=O)c1cnc2sccn2c1=O nan
16026568 53608 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 4.8 Cc1cc(C)c(NC(=O)C(C)n2c(=O)cc(-c3ccccc3)c3c(C)nn(C)c32)c(C)c1 nan
CHEMBL1602546 53608 0 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 4.8 Cc1cc(C)c(NC(=O)C(C)n2c(=O)cc(-c3ccccc3)c3c(C)nn(C)c32)c(C)c1 nan
1482197 53639 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 5 0 4 4.0 COc1ccc(C(=O)c2ccc(-c3ccc(OC)cc3)nc2)cc1 nan
CHEMBL1602835 53639 22 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 5 0 4 4.0 COc1ccc(C(=O)c2ccc(-c3ccc(OC)cc3)nc2)cc1 nan
16023008 53653 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 7 4.1 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5cccc(F)c5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1602958 53653 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 6 1 7 4.1 COc1ccc(-n2nc3c(N4CCC(C(=O)NCc5cccc(F)c5)CC4)nnc(C)c3c2C)cc1 nan
4077604 53719 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.1 O=C(NCC1CCCO1)c1ccc2c(=O)n(-c3ccc(F)cc3)c(=S)[nH]c2c1 nan
CHEMBL1603522 53719 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 3.1 O=C(NCC1CCCO1)c1ccc2c(=O)n(-c3ccc(F)cc3)c(=S)[nH]c2c1 nan
16008430 53796 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 6 0 6 5.0 COc1ccc(N2CCN(C(=O)CCc3c(C)nc4cc(-c5ccc(Cl)cc5)nn4c3C)CC2)cc1 nan
CHEMBL1604039 53796 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 6 0 6 5.0 COc1ccc(N2CCN(C(=O)CCc3c(C)nc4cc(-c5ccc(Cl)cc5)nn4c3C)CC2)cc1 nan
2319103 53806 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 7 2 6 4.7 CC(=O)Nc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 nan
CHEMBL1604161 53806 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 556 7 2 6 4.7 CC(=O)Nc1ccc(S(=O)(=O)[N-]c2nc3ccccc3nc2-[n+]2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 nan
1105833 53865 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 0 2 5.2 N#Cc1c(-c2cccc(F)c2)cc(-c2ccccc2)nc1Br nan
CHEMBL1604724 53865 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 2 0 2 5.2 N#Cc1c(-c2cccc(F)c2)cc(-c2ccccc2)nc1Br nan
13283806 53979 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 3 4.2 O=S1(=O)c2ccccc2N(Cc2ccccc2)c2ccccc21 nan
CHEMBL1605626 53979 1 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 2 0 3 4.2 O=S1(=O)c2ccccc2N(Cc2ccccc2)c2ccccc21 nan
606829 54061 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 1 2 5.1 Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
CHEMBL1606319 54061 16 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 1 2 5.1 Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)cc1 nan
2877673 54101 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 0 4 4.3 CCCC(=O)N1CCN(c2ccc(C(=O)c3ccc(OC)c(Br)c3)cc2F)CC1 nan
CHEMBL1606636 54101 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 0 4 4.3 CCCC(=O)N1CCN(c2ccc(C(=O)c3ccc(OC)c(Br)c3)cc2F)CC1 nan
16025505 54165 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.1 CC(C)c1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1607091 54165 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.1 CC(C)c1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
16019209 54179 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
CHEMBL1607174 54179 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 7 4.2 COc1ccc(Cn2c(=O)c3oc4ccccc4c3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1 nan
1166591 54278 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 5.4 COc1ccc(-c2cc(C(F)(F)F)nc(SCCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1608012 54278 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 5.4 COc1ccc(-c2cc(C(F)(F)F)nc(SCCC(=O)Nc3ccccc3F)n2)cc1 nan
939124 54500 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 6 3.6 CC(=O)c1c(C)nc(Nc2nc3ccccc3s2)nc1C nan
CHEMBL1609840 54500 14 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 298 3 1 6 3.6 CC(=O)c1c(C)nc(Nc2nc3ccccc3s2)nc1C nan
15989162 54530 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 10 2 7 3.8 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(CC(=O)Nc2c(C)cc(C)cc2C)c1=O nan
CHEMBL1610075 54530 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 10 2 7 3.8 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(CC(=O)Nc2c(C)cc(C)cc2C)c1=O nan
2542807 54567 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 4 4.2 Cc1cc(C)c(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C)c1 nan
CHEMBL1610420 54567 13 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 1 4 4.2 Cc1cc(C)c(NC(=O)CSc2nc(C)cc(C)c2C#N)c(C)c1 nan
1192919 54696 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2ccc(F)cc2)cc1 nan
CHEMBL1611527 54696 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 4 5.1 COc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2ccc(F)cc2)cc1 nan
16024853 54817 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 4 4.2 O=C(NCCc1ccccc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1612612 54817 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 4 4.2 O=C(NCCc1ccccc1)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
24789826 55065 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1307717 55065 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
CHEMBL1616626 55065 0 None -56 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 1 4 5.8 CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 nan
135448704 55259 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
CHEMBL1319156 55259 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
CHEMBL1618027 55259 34 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 1 4 4 1.4 N=C(N)Nc1nc(O)c2cc(Br)ccc2n1 nan
3773369 55717 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
CHEMBL1483432 55717 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
CHEMBL1622111 55717 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 4 1 5 2.9 COc1ccc(CCn2c(S)nc3ccccc3c2=O)cc1 nan
6886091 107860 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 1 6 3.2 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3cc4cc(Br)ccc4o3)ccc21 nan
CHEMBL3192586 107860 7 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 3 1 6 3.2 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3cc4cc(Br)ccc4o3)ccc21 nan
3221539 107919 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 8 0 6 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\CCOC)S3 nan
CHEMBL3193316 107919 4 None -2 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 8 0 6 3.2 CCOc1ccc2nc3c(cc2c1)CN(CCOC)/C(=N\CCOC)S3 nan
9615796 108248 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.3 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3ccc(Cl)cc3)ccc21 nan
CHEMBL3197069 108248 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 1 5 2.3 Cn1c(=O)n(C)c2cc(/C=N/NC(=O)c3ccc(Cl)cc3)ccc21 nan
24892226 108338 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 0 9 2.2 COC(=O)Cn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
CHEMBL3197975 108338 9 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 8 0 9 2.2 COC(=O)Cn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2c(OC)ccc(OC)c21 nan
6341421 108390 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 3 3.6 CCCn1c(C)cs/c1=N\C(=S)Nc1ccccc1 nan
CHEMBL3198424 108390 6 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 3 3.6 CCCn1c(C)cs/c1=N\C(=S)Nc1ccccc1 nan
6065517 108803 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 5 2 4 1.1 CC(C)NC(=O)CC(=O)N/N=C/c1cccs1 nan
CHEMBL3209441 108803 4 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 253 5 2 4 1.1 CC(C)NC(=O)CC(=O)N/N=C/c1cccs1 nan
135485035 108953 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.9 COc1ccc(Cl)cc1/N=C/c1c(O)oc2ccccc2c1=O nan
CHEMBL3211560 108953 10 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 5 3.9 COc1ccc(Cl)cc1/N=C/c1c(O)oc2ccccc2c1=O nan
17584634 109156 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 0 5 2.7 COc1ccc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2Cc2ccc(F)cc2)cc1 nan
CHEMBL3214247 109156 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 0 5 2.7 COc1ccc(C(=O)/N=C2\SC3CS(=O)(=O)CC3N2Cc2ccc(F)cc2)cc1 nan
6869045 112598 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
CHEMBL3194304 112598 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
CHEMBL3301898 112598 4 None -1 2 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 7 2 5 1.8 NCCCCCC(=O)N/N=C/c1coc2ccccc2c1=O nan
658981 117064 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 1 5 2.7 CCOC(=O)c1c(N)sc(=S)c2c1CCC2 nan
CHEMBL3392035 117064 12 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 2 1 5 2.7 CCOC(=O)c1c(N)sc(=S)c2c1CCC2 nan
2241546 120411 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.8 Cc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1 nan
CHEMBL353651 120411 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.8 Cc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1 nan
878295 173213 33 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 1 1 1 3.8 O=c1cc(-c2ccccc2)c2cc(Cl)ccc2[nH]1 nan
CHEMBL452292 173213 33 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 255 1 1 1 3.8 O=c1cc(-c2ccccc2)c2cc(Cl)ccc2[nH]1 nan
16010872 199071 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 7 4.4 COc1cc2nc(NCCC(C)C)n3nc(-c4ccccc4)nc3c2cc1OC nan
CHEMBL587492 199071 7 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 7 4.4 COc1cc2nc(NCCC(C)C)n3nc(-c4ccccc4)nc3c2cc1OC nan
16017892 199130 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 6 3.4 CCOc1ccc(NC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)cc1 nan
CHEMBL589232 199130 5 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 6 3.4 CCOc1ccc(NC(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)cc1 nan
1370186 199680 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 4 4.8 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 nan
CHEMBL593119 199680 11 None - 1 Human 4.5 pPotency = 4.5 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 5 1 4 4.8 Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 nan
372 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
8974 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
CHEMBL285819 58 103 None -107 5 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 4 9 -1.3 OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(Cl)nc2N nan
16019683 24079 1 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.6 Cc1ccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1338399 24079 1 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 1 7 2.6 Cc1ccc(CNC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
3486944 25001 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 0 4 2.5 Cc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
CHEMBL1346519 25001 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 0 4 2.5 Cc1cc(C=C2C(=O)N(C)C(=O)N(C)C2=O)c(C)n1-c1ccccc1 nan
665622 30153 7 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 11 2.8 CC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
CHEMBL1390005 30153 7 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 11 2.8 CC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
16019552 35191 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 8 4.1 Cc1ccc(CNc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)cc1 nan
CHEMBL1435107 35191 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 8 4.1 Cc1ccc(CNc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)cc1 nan
665286 35580 9 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 3.2 CCC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
CHEMBL1439367 35580 9 None 3 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 6 1 11 3.2 CCC1(C)Cc2c(sc3c2c2ncnn2c2nnc(SCC(=O)NCc4ccco4)n32)CO1 nan
2054021 35804 15 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 7 3.6 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nccs1 nan
CHEMBL1441380 35804 15 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 7 3.6 O=C(CSc1ncnc2c1oc1ccccc12)Nc1nccs1 nan
1395606 35842 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 1 5 4.7 CCOc1ccc(-n2nc3ccc(NC(=O)c4ccc(C)cc4C)cc3n2)cc1 nan
CHEMBL1441729 35842 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 5 1 5 4.7 CCOc1ccc(-n2nc3ccc(NC(=O)c4ccc(C)cc4C)cc3n2)cc1 nan
997264 38868 5 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
CHEMBL1467097 38868 5 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
1552186 39529 17 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 5 1 4 6.8 Cc1ccc2nc(-c3ccc(NC(=O)COc4ccc(Br)cc4Br)cc3)sc2c1 nan
CHEMBL1472916 39529 17 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 5 1 4 6.8 Cc1ccc2nc(-c3ccc(NC(=O)COc4ccc(Br)cc4Br)cc3)sc2c1 nan
16009715 41950 11 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
CHEMBL1494680 41950 11 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 5 4.7 Fc1ccc(-c2nnn3c2nc(NCc2ccccc2)c2ccccc23)cc1 nan
16018178 48251 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.5 Cc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
CHEMBL1552994 48251 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 4 5.5 Cc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
15991072 52421 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 4 6.3 O=C(Nc1ccc2oc(-c3ccc(Br)cc3)nc2c1)c1cc2ccccc2o1 nan
CHEMBL1590554 52421 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 3 1 4 6.3 O=C(Nc1ccc2oc(-c3ccc(Br)cc3)nc2c1)c1cc2ccccc2o1 nan
2988582 52610 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 5.1 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)c1ccc(Cl)cc1 nan
CHEMBL1592961 52610 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 5.1 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)c1ccc(Cl)cc1 nan
15988483 52673 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 2 4 3.7 CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)cc1 nan
CHEMBL1593961 52673 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 2 4 3.7 CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CC(c2ccccc2)CC3=O)cc1 nan
1367050 53984 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 6 3.8 CCOc1ccc(-n2nc3ccc(NC(=O)COc4ccccc4)cc3n2)cc1 nan
CHEMBL1605697 53984 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 7 1 6 3.8 CCOc1ccc(-n2nc3ccc(NC(=O)COc4ccccc4)cc3n2)cc1 nan
4429605 71694 12 None -1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 0 7 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(S(=O)(=O)N(C)c3ccccc3)cc2)n(C)c1C nan
CHEMBL1964939 71694 12 None -1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 0 7 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccc(S(=O)(=O)N(C)c3ccccc3)cc2)n(C)c1C nan
16010338 5877 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 2 8 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCNC(C)=O)c2cc(Cl)ccc23)cc1 nan
CHEMBL1079456 5877 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 7 2 8 2.9 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCNC(C)=O)c2cc(Cl)ccc23)cc1 nan
135446757 8053 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.9 O=c1[nH]c(/C=C/c2ccc(Br)cc2)nc2ccccc12 nan
CHEMBL1091028 8053 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.9 O=c1[nH]c(/C=C/c2ccc(Br)cc2)nc2ccccc12 nan
250997 10490 3 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 10 3.5 COc1cc(SSc2cc(OC)cc([N+](=O)[O-])c2N)c(N)c([N+](=O)[O-])c1 nan
CHEMBL116548 10490 3 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 10 3.5 COc1cc(SSc2cc(OC)cc([N+](=O)[O-])c2N)c(N)c([N+](=O)[O-])c1 nan
16019609 10612 10 None -223 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)c2ccccc2)c2sccc23)cc1 nan
CHEMBL1170098 10612 10 None -223 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 4.7 Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC(C)c2ccccc2)c2sccc23)cc1 nan
16019288 10691 7 None -234 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 8 4.2 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCC1)c1sccc12 nan
CHEMBL1170696 10691 7 None -234 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 4 1 8 4.2 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCC1)c1sccc12 nan
16019546 10710 6 None -676 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 8 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 nan
CHEMBL1170891 10710 6 None -676 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 8 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 nan
16019576 10897 6 None -1995 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 9 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1172726 10897 6 None -1995 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 9 3.8 O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
7246142 10922 8 None -85 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 8 3.6 CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
CHEMBL1172934 10922 8 None -85 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 4 1 8 3.6 CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 nan
747391 15665 17 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.8 CCOC(=O)c1sc(NC(=O)c2ccco2)nc1-c1ccccc1 nan
CHEMBL1222145 15665 17 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 5 1 6 3.8 CCOC(=O)c1sc(NC(=O)c2ccco2)nc1-c1ccccc1 nan
5309696 19558 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 2.8 CCn1c(=O)cc(OCC(=O)Nc2nc(C)cs2)c2ccccc21 nan
CHEMBL1299766 19558 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 1 6 2.8 CCn1c(=O)cc(OCC(=O)Nc2nc(C)cs2)c2ccccc21 nan
1716419 19633 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 5 4.7 CCCCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
CHEMBL1300444 19633 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 5 4.7 CCCCNC(=O)c1nn2c(C(F)(F)F)cc(-c3ccc(OC)cc3)nc2c1Br nan
135468422 19659 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 2 9 4.4 COc1ccc(NC(=O)CSc2nc3nnc(C)c-3c(N)n2-c2ccc(Cl)c(C)c2)cc1OC nan
CHEMBL1300619 19659 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 2 9 4.4 COc1ccc(NC(=O)CSc2nc3nnc(C)c-3c(N)n2-c2ccc(Cl)c(C)c2)cc1OC nan
5112617 19811 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 3 4 2.2 CC(C)CC(=O)NC(=S)Nc1sc2c(c1C(N)=O)CCC2 nan
CHEMBL1301780 19811 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 3 4 2.2 CC(C)CC(=O)NC(=S)Nc1sc2c(c1C(N)=O)CCC2 nan
1440349 19846 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.4 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1c(C)cccc1C)CCC3 nan
CHEMBL1302141 19846 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.4 Cc1cc2cc3c(cc2nc1SCC(=O)Nc1c(C)cccc1C)CCC3 nan
648939 19848 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
CHEMBL1302172 19848 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 5 1 5 3.1 Cc1cc(C)c2cc(C#N)c(SCC(=O)NCC3CCCO3)nc2c1 nan
3221134 19890 5 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 4.0 COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1ccccc1C nan
CHEMBL1302436 19890 5 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 6 4.0 COCCN(Cc1cc2cc(C)ccc2n2nnnc12)C(S)=Nc1ccccc1C nan
1864418 19892 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 6 3.5 CC(C)Cc1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
CHEMBL1302453 19892 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 6 3.5 CC(C)Cc1nc2sc3c(SCC(N)=O)ncnc3c2c2c1CCC2 nan
22334119 19909 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 8 2 7 2.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCc3ccc(F)cc3)c3ccccc3c2=O)cc1OC nan
CHEMBL1302552 19909 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 8 2 7 2.6 COc1ccc(-n2nc(C(=O)NCC(=O)NCc3ccc(F)cc3)c3ccccc3c2=O)cc1OC nan
1173246 20073 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 2 6 4.2 Cc1ccc(C)c2c1cc(C)c1nnc(SCC(=O)Nc3cccc(C(=O)O)c3)n12 nan
CHEMBL1303849 20073 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 5 2 6 4.2 Cc1ccc(C)c2c1cc(C)c1nnc(SCC(=O)Nc3cccc(C(=O)O)c3)n12 nan
135455179 20192 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
135480855 20192 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
135554164 20192 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
CHEMBL1304888 20192 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 3 1 4 3.0 Cc1cccc(NC2=NC(=O)C(Cc3ccccc3)S2)n1 nan
16188302 20273 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 5.4 CCN(C(=O)c1cc2c(O)nc3ccc(C)cc3c2s1)c1cccc(C)c1 nan
CHEMBL1305636 20273 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 1 4 5.4 CCN(C(=O)c1cc2c(O)nc3ccc(C)cc3c2s1)c1cccc(C)c1 nan
3612019 20331 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 4 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(Cl)s1 nan
CHEMBL1305985 20331 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 4 2.5 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(Cl)s1 nan
4243407 20493 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 4.8 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NC(c5ccccc5)c5ccccc5)cnc4c3cc2CO1 nan
CHEMBL1307313 20493 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 5 1 7 4.8 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NC(c5ccccc5)c5ccccc5)cnc4c3cc2CO1 nan
664182 20538 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 7 4.9 CC(C)c1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
CHEMBL1307669 20538 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 7 4.9 CC(C)c1nc2sc3c(SCC(=O)NCc4ccco4)ncnc3c2c2c1CCC2 nan
2823681 20649 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 1 4.9 Cc1cc(C)c2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
CHEMBL1308537 20649 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 2 2 1 4.9 Cc1cc(C)c2[nH]c(C(=O)Nc3ccc(F)cc3Br)cc2c1 nan
135443911 20663 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.5 COc1ccc(N2CC(=O)C(c3nc(-c4ccccc4)cs3)=C2N)cc1 nan
CHEMBL1308652 20663 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 4 1 6 3.5 COc1ccc(N2CC(=O)C(c3nc(-c4ccccc4)cs3)=C2N)cc1 nan
7206305 20736 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 8 2.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc4c(c3)OCO4)nn2)no1 nan
CHEMBL1309267 20736 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 8 2.9 Cc1cc(NC(=O)CSc2ccc(-c3ccc4c(c3)OCO4)nn2)no1 nan
546665 20862 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 5 3.0 CC(C)(C)S(=O)(=O)c1cnc(-c2ccc(Cl)cc2)nc1N nan
CHEMBL1310343 20862 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 1 5 3.0 CC(C)(C)S(=O)(=O)c1cnc(-c2ccc(Cl)cc2)nc1N nan
54693834 20947 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 5 2.9 CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4ccco4)c(=O)n1c23 nan
CHEMBL1311072 20947 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 3 2 5 2.9 CC1CCc2cc(F)cc3c(O)c(C(=O)NCc4ccco4)c(=O)n1c23 nan
16746300 20970 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 618 8 0 8 6.1 COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CC(=O)N1CCN(c2ccccc2)CC1)c1ccc2c(c1)OCO2 nan
CHEMBL1311273 20970 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 618 8 0 8 6.1 COc1cc(OC)c2c(-c3ccccc3)cc(=O)oc2c1C(CC(=O)N1CCN(c2ccccc2)CC1)c1ccc2c(c1)OCO2 nan
3413238 20972 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 7 2.8 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4ncsc4c3)sc2c1 nan
CHEMBL1311288 20972 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 7 2.8 NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc4ncsc4c3)sc2c1 nan
245201 20986 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 214 3 1 7 0.9 CNc1nc(SC)n(C)c(=O)c1N=O nan
CHEMBL1311401 20986 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 214 3 1 7 0.9 CNc1nc(SC)n(C)c(=O)c1N=O nan
16194626 21035 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 6 2.6 COc1ccc(N2CCN(C(c3cccs3)C(C)NS(C)(=O)=O)CC2)cc1 nan
CHEMBL1311746 21035 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 6 2.6 COc1ccc(N2CCN(C(c3cccs3)C(C)NS(C)(=O)=O)CC2)cc1 nan
3586870 21146 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 3 0 4 3.4 COc1ccc(Oc2cnc3ccccc3n2)cc1 nan
CHEMBL1312526 21146 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 252 3 0 4 3.4 COc1ccc(Oc2cnc3ccccc3n2)cc1 nan
645988 21175 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.3 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccco1 nan
CHEMBL1312719 21175 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.3 O=C(CSc1nc2c(c(C(F)(F)F)n1)CCc1ccccc1-2)NCc1ccco1 nan
660699 21249 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 2 7 3.6 N#Cc1c(N)nc(SCC(=O)NCCc2ccccc2)c(C#N)c1-c1cccs1 nan
CHEMBL1313254 21249 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 7 2 7 3.6 N#Cc1c(N)nc(SCC(=O)NCCc2ccccc2)c(C#N)c1-c1cccs1 nan
6619041 21251 8 None -6 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 9 2 8 3.2 CCOc1ccc(NC(=O)CNC(=O)c2nn(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc23)cc1 nan
CHEMBL1313270 21251 8 None -6 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 9 2 8 3.2 CCOc1ccc(NC(=O)CNC(=O)c2nn(-c3ccc(OC)c(OC)c3)c(=O)c3ccccc23)cc1 nan
2731590 21291 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1-c1ccc2c(c1)OCCO2 nan
CHEMBL1313595 21291 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 1 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1-c1ccc2c(c1)OCCO2 nan
11957277 21308 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 0 8 3.9 O=[N+]([O-])C(/C=C(\Cl)[N+](=O)[O-])=C1N(Cc2ccc(Cl)nc2)CCN1Cc1ccc(Cl)nc1 nan
CHEMBL1313693 21308 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 0 8 3.9 O=[N+]([O-])C(/C=C(\Cl)[N+](=O)[O-])=C1N(Cc2ccc(Cl)nc2)CCN1Cc1ccc(Cl)nc1 nan
16012576 21368 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 7 4.1 COc1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(OC)c1 nan
CHEMBL1314269 21368 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 1 7 4.1 COc1cc(NC(=O)CCc2c(C)nc3c4c(C)cc(C)nc4nn3c2C)cc(OC)c1 nan
16020367 21374 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 8 4.4 COC(=O)c1ccccc1NC(=O)c1cc2c(-c3ccc(OC)c(OC)c3)nn(C)c2s1 nan
CHEMBL1314309 21374 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 8 4.4 COC(=O)c1ccccc1NC(=O)c1cc2c(-c3ccc(OC)c(OC)c3)nn(C)c2s1 nan
16009631 21377 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 7 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1 nan
CHEMBL1314331 21377 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 7 4.5 COc1ccc(C(=O)Nc2cccc(OCc3cc(=O)n4c5c(sc4n3)CCCC5)c2)cc1 nan
16008545 21378 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 6 4.3 COc1ccc(C(=O)c2cn(Cc3cccc(C)c3)c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1314337 21378 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 0 6 4.3 COc1ccc(C(=O)c2cn(Cc3cccc(C)c3)c3cc4c(cc3c2=O)OCO4)cc1 nan
16018962 21383 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.6 O=C(NCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1314402 21383 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 5 3.6 O=C(NCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16026094 21394 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 3.1 CC(C)c1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
CHEMBL1314533 21394 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 4 1 7 3.1 CC(C)c1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
2152595 21408 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 0 7 2.9 COC(=O)c1ccc2c(c1)s/c(=N/C(=O)c1ccc(S(=O)(=O)N3CCCCC3)cc1)n2C nan
CHEMBL1314815 21408 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 0 7 2.9 COC(=O)c1ccc2c(c1)s/c(=N/C(=O)c1ccc(S(=O)(=O)N3CCCCC3)cc1)n2C nan
135437061 21409 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1Cl nan
CHEMBL1314816 21409 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 3 6 3.9 Cc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1Cl nan
16019424 21414 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 0 8 4.5 CC1CCCN(c2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)C1 nan
CHEMBL1314919 21414 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 0 8 4.5 CC1CCCN(c2nc3c(S(=O)(=O)c4ccc(C(C)C)cc4)nnn3c3ccsc23)C1 nan
16010115 21418 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 2.8 Cc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
CHEMBL1314966 21418 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 2.8 Cc1ccc(CNC(=O)C2CCN(c3nc4ccccc4n(C)c3=O)CC2)cc1 nan
16020210 21423 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 8 2 8 4.0 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
CHEMBL1315042 21423 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 576 8 2 8 4.0 CCc1ccc(NC(=O)Cn2c(=O)n(-c3ccccc3)c(=O)c3ccc(C(=O)NCc4ccc5c(c4)OCO5)cc32)cc1 nan
16021834 21435 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2c(C)cccc2C)c(-c2ccccc2)n1 nan
CHEMBL1315205 21435 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2c(C)cccc2C)c(-c2ccccc2)n1 nan
3516704 21438 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 7 4.4 CCOCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1315294 21438 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 10 1 7 4.4 CCOCCCn1c(SCC(=O)NCc2ccccc2)nc2c(sc3ccccc32)c1=O nan
16009766 21454 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 2 5 6.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)cc1 nan
CHEMBL1315409 21454 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 6 2 5 6.1 CCOc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)c2cc3ccccc3o2)cc1 nan
16018863 21461 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 5 3.8 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1Br nan
CHEMBL1315473 21461 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 5 3.8 O=C(CCCn1c(=O)c2cccn2c2cccnc21)Nc1ccccc1Br nan
16026940 21479 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1cccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)c1 nan
CHEMBL1315714 21479 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1cccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)c1 nan
2808363 21501 25 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 5 2.7 COC(=O)c1sccc1NC(=O)c1ccc(C#N)cc1 nan
CHEMBL1315955 21501 25 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 3 1 5 2.7 COC(=O)c1sccc1NC(=O)c1ccc(C#N)cc1 nan
16019191 21515 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 2 5.2 O=C(CCc1cn(Cc2ccc(F)cc2)c2ccccc12)NC1CCCCC1 nan
CHEMBL1316117 21515 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 6 1 2 5.2 O=C(CCc1cn(Cc2ccc(F)cc2)c2ccccc12)NC1CCCCC1 nan
16031991 21520 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 4.1 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3sc(C)nc3C)nn2)cc1 nan
CHEMBL1316148 21520 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 8 4.1 CCOC(=O)c1ccc(NC(=O)CSc2ccc(-c3sc(C)nc3C)nn2)cc1 nan
2135282 21521 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1316149 21521 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 8 4.0 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(OC)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
16008335 21526 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 2 6 4.4 O=C(Nc1ccc(C(F)(F)F)cc1)C1CCC(CNS(=O)(=O)c2cccc3nsnc23)CC1 nan
CHEMBL1316232 21526 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 2 6 4.4 O=C(Nc1ccc(C(F)(F)F)cc1)C1CCC(CNS(=O)(=O)c2cccc3nsnc23)CC1 nan
16034305 21538 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 5 4.5 CC(C)CCNC(=O)c1cc(-c2cccnc2)nc2ccc(S(=O)(=O)N3CCC(C)CC3)cc12 nan
CHEMBL1316467 21538 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 7 1 5 4.5 CC(C)CCNC(=O)c1cc(-c2cccnc2)nc2ccc(S(=O)(=O)N3CCC(C)CC3)cc12 nan
3162808 21542 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 6 4.8 COc1ccc(C2CC(=O)c3cnc4c(-c5ccc(F)cc5)c(C)nn4c3C2)cc1OC nan
CHEMBL1316500 21542 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 4 0 6 4.8 COc1ccc(C2CC(=O)c3cnc4c(-c5ccc(F)cc5)c(C)nn4c3C2)cc1OC nan
3674872 21543 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 3.0 CCn1c(SCC(=O)Nc2ccccc2C(=O)OC)nc2ccsc2c1=O nan
CHEMBL1316511 21543 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 6 1 8 3.0 CCn1c(SCC(=O)Nc2ccccc2C(=O)OC)nc2ccsc2c1=O nan
7223037 21590 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 2 4 4.3 CCc1ccccc1NC(=O)C(=O)NCCc1sc(-c2cccc(C)c2)nc1C nan
CHEMBL1317197 21590 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 2 4 4.3 CCc1ccccc1NC(=O)C(=O)NCCc1sc(-c2cccc(C)c2)nc1C nan
16026110 21600 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 5 4.2 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
CHEMBL1317332 21600 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 5 4.2 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
7205418 21614 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1ccc(-n2ncc3c(NCc4ccccc4)ncnc32)cc1Cl nan
CHEMBL1317524 21614 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1ccc(-n2ncc3c(NCc4ccccc4)ncnc32)cc1Cl nan
16008313 21627 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 2 6 4.4 Cc1ccc(NC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)c(Cl)c1 nan
CHEMBL1317641 21627 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 6 2 6 4.4 Cc1ccc(NC(=O)C2CCC(CNS(=O)(=O)c3cccc4nsnc34)CC2)c(Cl)c1 nan
16026429 21631 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 1 7 1.2 Cc1cc2c(cc1NS(=O)(=O)c1cccc(C#N)c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1317692 21631 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 3 1 7 1.2 Cc1cc2c(cc1NS(=O)(=O)c1cccc(C#N)c1)n(C)c(=O)c(=O)n2C nan
15989759 21643 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 5 3.3 Cc1ccc2nc(NCc3ccc(F)cc3)c3nncn3c2c1 nan
CHEMBL1317896 21643 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 5 3.3 Cc1ccc2nc(NCc3ccc(F)cc3)c3nncn3c2c1 nan
16016705 21660 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 2.6 O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccs1 nan
CHEMBL1318069 21660 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 5 1 4 2.6 O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccs1 nan
15988587 21667 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NCc1ccccc1Cl nan
CHEMBL1318209 21667 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 507 6 1 6 4.5 O=C(Cn1c(=O)n(Cc2ccc(F)cc2)c(=O)c2sc3ccccc3c21)NCc1ccccc1Cl nan
7245933 21671 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 3.4 CCOc1ccc(S(=O)(=O)c2cc3cccc(OCC)c3oc2=O)cc1 nan
CHEMBL1318269 21671 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 6 0 6 3.4 CCOc1ccc(S(=O)(=O)c2cc3cccc(OCC)c3oc2=O)cc1 nan
1164100 21709 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 0 6 3.4 COc1cccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)c1 nan
CHEMBL1318572 21709 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 0 6 3.4 COc1cccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)c1 nan
4077176 21719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 3 5.6 CCC(C)NC(=O)c1cc(Sc2cccc(Cl)c2)nc2ccccc12 nan
CHEMBL1318673 21719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 3 5.6 CCC(C)NC(=O)c1cc(Sc2cccc(Cl)c2)nc2ccccc12 nan
4055959 21744 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 3.6 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C)c(C)c1 nan
CHEMBL1318877 21744 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 5 3.6 Cc1ccc(NC(=O)c2oc3ccc(S(=O)(=O)N4CCOCC4)cc3c2C)c(C)c1 nan
16022946 21821 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1319510 21821 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.6 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5ccccc5C)CC4)nnc(C)c3c2C)cc1 nan
2967498 21883 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 1 5 3.6 O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1 nan
CHEMBL1320036 21883 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 5 1 5 3.6 O=C(Nc1nccs1)c1ccc(COc2ccccc2)o1 nan
5139336 21897 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 4.4 Cc1cccc2sc(NC(=O)c3ccc(OCC4CCCO4)cc3)nc12 nan
CHEMBL1320175 21897 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 4.4 Cc1cccc2sc(NC(=O)c3ccc(OCC4CCCO4)cc3)nc12 nan
16030546 21904 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 3.5 COc1ccccc1C(=O)Nc1cccc(OCc2cc(=O)n3ccccc3n2)c1 nan
CHEMBL1320207 21904 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 6 3.5 COc1ccccc1C(=O)Nc1cccc(OCc2cc(=O)n3ccccc3n2)c1 nan
16030772 21949 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.8 Cn1c(=O)c2c(SCC(=O)NCc3ccco3)nc(-c3ccccc3F)nc2n(C)c1=O nan
CHEMBL1320595 21949 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 1.8 Cn1c(=O)c2c(SCC(=O)NCc3ccco3)nc(-c3ccccc3F)nc2n(C)c1=O nan
16016685 21959 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 2 3 4.3 CCCCNC(=O)Nc1ccc2c(c1)N(C)C(=O)c1ccccc1S2 nan
CHEMBL1320647 21959 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 4 2 3 4.3 CCCCNC(=O)Nc1ccc2c(c1)N(C)C(=O)c1ccccc1S2 nan
16033946 21965 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 7 4.4 CCOC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(Cl)c2)cc1 nan
CHEMBL1320676 21965 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 7 4.4 CCOC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(Cl)c2)cc1 nan
944701 21971 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 6 2.9 COc1ccc2nc(O)c(COC(=O)c3ccco3)cc2c1 nan
CHEMBL1320788 21971 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 4 1 6 2.9 COc1ccc2nc(O)c(COC(=O)c3ccco3)cc2c1 nan
5135847 22003 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 2 4 3.8 CCOC(=O)c1cc2c(nc1N=C(S)NCc1ccccc1)CCCC2 nan
CHEMBL1321064 22003 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 2 4 3.8 CCOC(=O)c1cc2c(nc1N=C(S)NCc1ccccc1)CCCC2 nan
3634798 22006 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 7 4.5 CCOC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1CCc1ccccc1 nan
CHEMBL1321100 22006 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 7 4.5 CCOC(=O)CSc1nc2c(sc3ccccc32)c(=O)n1CCc1ccccc1 nan
6473515 22022 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 2 5 3.1 COc1ccc(S(=O)(=O)Nc2ccccn2)cc1C(=O)Nc1ccccc1 nan
CHEMBL1321208 22022 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 2 5 3.1 COc1ccc(S(=O)(=O)Nc2ccccn2)cc1C(=O)Nc1ccccc1 nan
16026080 22057 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1321609 22057 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
661514 22062 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 8 2.7 COc1ccc(-c2nnc3sc(CN4C(=O)c5ccccc5C4=O)nn23)cc1 nan
CHEMBL1321633 22062 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 0 8 2.7 COc1ccc(-c2nnc3sc(CN4C(=O)c5ccccc5C4=O)nn23)cc1 nan
963196 22100 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 5 1 3 4.5 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)c(C)c1 nan
CHEMBL1321920 22100 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 5 1 3 4.5 Cc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)c(C)c1 nan
1034156 22103 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 2 4 2.9 Cc1cc2oc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c(C)c2cc1C nan
CHEMBL1321976 22103 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 2 4 2.9 Cc1cc2oc(C(=O)NCc3ccc(S(N)(=O)=O)cc3)c(C)c2cc1C nan
16026098 22104 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 5 3.7 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
CHEMBL1321983 22104 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 4 1 5 3.7 CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccc(C)o2)CC1 nan
1480476 22157 24 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccc(Cl)cc2)c1C#N nan
CHEMBL1322430 22157 24 None -12 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.6 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccc(Cl)cc2)c1C#N nan
16021832 22275 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2cccc(C)c2C)c(-c2ccccc2)n1 nan
CHEMBL1323559 22275 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 4 4.7 CSc1ncc(C(=O)Nc2cccc(C)c2C)c(-c2ccccc2)n1 nan
4868391 22322 34 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1Cc1ccccc1 nan
CHEMBL1323909 22322 34 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 3 4.5 Sc1ncc(-c2ccc(Cl)cc2)n1Cc1ccccc1 nan
7284118 22326 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 5 3.2 CCOc1ccc(CCNC(=O)Cn2ccc3ccccc3c2=O)cc1OCC nan
CHEMBL1323924 22326 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 9 1 5 3.2 CCOc1ccc(CCNC(=O)Cn2ccc3ccccc3c2=O)cc1OCC nan
2135896 22344 6 None -158 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 2 7 2.4 COc1ccc(OC)c(NC(=O)c2nnn(CCc3ccccc3)c2N)c1 nan
CHEMBL1324085 22344 6 None -158 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 2 7 2.4 COc1ccc(OC)c(NC(=O)c2nnn(CCc3ccccc3)c2N)c1 nan
3422137 22349 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 0 9 2.0 COCCn1c(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
CHEMBL1324117 22349 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 8 0 9 2.0 COCCn1c(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)nc2c1c(=O)n(C)c(=O)n2C nan
16015664 22399 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 6 6.6 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(Cl)cc3)on2)cc1 nan
CHEMBL1324545 22399 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 7 1 6 6.6 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(Cl)cc3)on2)cc1 nan
5299986 22442 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 5 5.1 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C1CCN2CC1 nan
CHEMBL1324899 22442 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 4 1 5 5.1 N#Cc1cc2c(nc1SCC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C1CCN2CC1 nan
2967360 22463 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 4 5.3 Cc1ccc(N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)c2ccccc2)c(C)c1 nan
CHEMBL1325059 22463 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 1 4 5.3 Cc1ccc(N(Cc2cc3ccc(C)cc3nc2O)S(=O)(=O)c2ccccc2)c(C)c1 nan
4013085 22481 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.7 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 nan
CHEMBL1325232 22481 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 7 2.7 CCOC(=O)c1ccc(NC2Nc3cc(C)nn3S2)cc1 nan
4877095 22499 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.1 CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C nan
CHEMBL1325413 22499 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 4 1 6 4.1 CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C nan
16012280 22509 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(C)c1NC(=O)CCS(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
CHEMBL1325535 22509 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 7 1.7 Cc1cccc(C)c1NC(=O)CCS(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C nan
16011188 22522 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.4 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(C)cc1C nan
CHEMBL1325716 22522 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 5 4.4 COC(=O)c1cc2oc3ccccc3c2n1CC(=O)Nc1ccc(C)cc1C nan
709602 22530 5 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 2 5 3.6 Cc1c(NC(=O)c2nc[nH]n2)cccc1-c1nc2ccccc2s1 nan
CHEMBL1325780 22530 5 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 2 5 3.6 Cc1c(NC(=O)c2nc[nH]n2)cccc1-c1nc2ccccc2s1 nan
3619431 22593 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 0 4 5.7 O=C(c1cccs1)c1cn(CCOc2ccc(Cl)cc2)c2ccccc12 nan
CHEMBL1326440 22593 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 0 4 5.7 O=C(c1cccs1)c1cn(CCOc2ccc(Cl)cc2)c2ccccc12 nan
663870 22600 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1ccc(C(=O)OCc2cc3ccccc3nc2O)cc1 nan
CHEMBL1326511 22600 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 4 3.6 Cc1ccc(C(=O)OCc2cc3ccccc3nc2O)cc1 nan
16018929 22610 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 11 1 7 3.6 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1OCC nan
CHEMBL1326604 22610 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 11 1 7 3.6 CCOc1ccc(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)cc1OCC nan
17583882 22619 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 3.5 CCCCc1cc(=O)oc2cc(OCC(=O)Nc3ccccn3)ccc12 nan
CHEMBL1326654 22619 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 1 5 3.5 CCCCc1cc(=O)oc2cc(OCC(=O)Nc3ccccn3)ccc12 nan
1477181 22663 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 3.7 CC(=O)c1cc(C#N)c(NCc2cc(-c3ccccc3)no2)nc1C nan
CHEMBL1327040 22663 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 3.7 CC(=O)c1cc(C#N)c(NCc2cc(-c3ccccc3)no2)nc1C nan
16034758 22671 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.6 COc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1OC nan
CHEMBL1327116 22671 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 6 2.6 COc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1OC nan
16008896 22679 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)cc1 nan
CHEMBL1327173 22679 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 4 1 5 3.0 COc1ccc(CNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)cc1 nan
4227789 22710 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 0 5 5.5 CCN(CC)C(=O)C1CCCN(c2ncnc3c2c(-c2ccccc2)cn3-c2cccc(C)c2)C1 nan
CHEMBL1327499 22710 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 6 0 5 5.5 CCN(CC)C(=O)C1CCCN(c2ncnc3c2c(-c2ccccc2)cn3-c2cccc(C)c2)C1 nan
16032611 22815 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 3 2.9 O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)C(=O)c1c[nH]c2ccccc12 nan
CHEMBL1328167 22815 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 4 2 3 2.9 O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)C(=O)c1c[nH]c2ccccc12 nan
1426216 22885 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.1 Cc1cc(=O)n2c(C(=O)Nc3ccc(C(=O)OC(C)C)cc3)c(C(=O)Nc3ccccc3)sc2n1 nan
CHEMBL1328860 22885 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 2 8 4.1 Cc1cc(=O)n2c(C(=O)Nc3ccc(C(=O)OC(C)C)cc3)c(C(=O)Nc3ccccc3)sc2n1 nan
857007 22886 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 4 4.2 Cc1cc2cc(C)c(SCC(=O)NCc3ccco3)nc2cc1C nan
CHEMBL1328861 22886 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 5 1 4 4.2 Cc1cc2cc(C)c(SCC(=O)NCc3ccco3)nc2cc1C nan
16015065 22899 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 6 5.3 CC(=O)c1cccc(NC(=O)c2sc(-n3nc(C)c(CCC(C)C)c3C)nc2C)c1 nan
CHEMBL1328989 22899 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 1 6 5.3 CC(=O)c1cccc(NC(=O)c2sc(-n3nc(C)c(CCC(C)C)c3C)nc2C)c1 nan
7294635 22926 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 4 4.7 Nc1c(C(=O)Nc2ccccc2Cl)c2ccccn2c1C(=O)c1ccccc1 nan
CHEMBL1329216 22926 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 2 4 4.7 Nc1c(C(=O)Nc2ccccc2Cl)c2ccccn2c1C(=O)c1ccccc1 nan
2986428 22957 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.0 CC(C)CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 nan
CHEMBL1329460 22957 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 8 4.0 CC(C)CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 nan
7422802 22961 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1ccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)cc1 nan
CHEMBL1329510 22961 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1ccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)cc1 nan
7889414 23007 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 10 1.5 CCCn1c(N)c(C(=O)CSc2ncnc3sccc23)c(=O)n(C)c1=O nan
CHEMBL1329885 23007 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 1 10 1.5 CCCn1c(N)c(C(=O)CSc2ncnc3sccc23)c(=O)n(C)c1=O nan
1038210 23017 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 0 8 2.7 CCOC(=O)CCSc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)OC2 nan
CHEMBL1329993 23017 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 6 0 8 2.7 CCOC(=O)CCSc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)OC2 nan
16009180 23064 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCO4)c3ccc(OC)cc3c2=O)cc1 nan
CHEMBL1330381 23064 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.2 CCc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCO4)c3ccc(OC)cc3c2=O)cc1 nan
1510063 23078 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 3.4 CCC(=O)c1cc2c(cc1NC(=O)c1ccccc1F)OCCO2 nan
CHEMBL1330472 23078 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 4 3.4 CCC(=O)c1cc2c(cc1NC(=O)c1ccccc1F)OCCO2 nan
16019798 23113 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)cc1OC nan
CHEMBL1330797 23113 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 6 2 6 2.6 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4[nH]c(=O)ccc4c3)C2)cc1OC nan
1078194 23162 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 2 5 3.5 Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)cc1C nan
CHEMBL1331082 23162 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 2 5 3.5 Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)Nc3ccccn3)cc2)cc1C nan
1367422 23164 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 6 3.6 O=C(NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1)c1ccco1 nan
CHEMBL1331090 23164 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 6 3.6 O=C(NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1)c1ccco1 nan
15990786 23187 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 13 2 5 6.4 CCCCN(CCCNC(=O)c1cc(Nc2ccc(OC)cc2)nc2ccccc12)Cc1ccccc1 nan
CHEMBL1331246 23187 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 13 2 5 6.4 CCCCN(CCCNC(=O)c1cc(Nc2ccc(OC)cc2)nc2ccccc12)Cc1ccccc1 nan
1426224 23195 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 2 6 4.1 CCc1ccc(NC(=O)c2c(C(=O)Nc3ccccc3)sc3nc(C)cc(=O)n23)cc1 nan
CHEMBL1331302 23195 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 5 2 6 4.1 CCc1ccc(NC(=O)c2c(C(=O)Nc3ccccc3)sc3nc(C)cc(=O)n23)cc1 nan
16009858 23224 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 2 6 5.7 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3OC)oc3ccccc23)cc1OCC nan
CHEMBL1331538 23224 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 2 6 5.7 CCOc1ccc(C(=O)Nc2c(C(=O)Nc3ccccc3OC)oc3ccccc23)cc1OCC nan
965763 23257 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 3.8 Cc1cc(OCC(=O)Nc2ccc3oc(=O)ccc3c2)ccc1Cl nan
CHEMBL1331830 23257 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 4 3.8 Cc1cc(OCC(=O)Nc2ccc3oc(=O)ccc3c2)ccc1Cl nan
4216258 23293 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 3 6 6.0 CCOc1ccccc1Nc1sc(C(=O)c2ccccc2)c(N)c1C(=O)Nc1ccccc1 nan
CHEMBL1332095 23293 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 8 3 6 6.0 CCOc1ccccc1Nc1sc(C(=O)c2ccccc2)c(N)c1C(=O)Nc1ccccc1 nan
2670204 23304 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 0 9 1.7 COc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)c(OC)c1 nan
CHEMBL1332216 23304 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 7 0 9 1.7 COc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)c(OC)c1 nan
2151601 23323 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
CHEMBL1332323 23323 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 5.5 Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 nan
16012517 23327 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 5 6.3 CCOc1ccc(-c2cc(NC(=O)Nc3ccccc3C(F)(F)F)c(C(=O)OC)s2)cc1 nan
CHEMBL1332340 23327 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 2 5 6.3 CCOc1ccc(-c2cc(NC(=O)Nc3ccccc3C(F)(F)F)c(C(=O)OC)s2)cc1 nan
2243529 23328 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 0 3 3.7 O=C(c1cccs1)N1C(=O)c2cccc3cccc1c23 nan
CHEMBL1332342 23328 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 279 1 0 3 3.7 O=C(c1cccs1)N1C(=O)c2cccc3cccc1c23 nan
867009 23445 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 3 3.7 COc1ccc(Cl)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C nan
CHEMBL1333261 23445 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 2 3 3.7 COc1ccc(Cl)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C nan
677173 23472 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 2 4 3.5 CCCc1nnc(N=C(S)Nc2ccccc2)s1 nan
CHEMBL1333504 23472 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 278 4 2 4 3.5 CCCc1nnc(N=C(S)Nc2ccccc2)s1 nan
3623159 23506 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 1 4 5.3 CCOc1ccc(Sc2cc(C(=O)NC(C)CC)c3ccccc3n2)cc1 nan
CHEMBL1333744 23506 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 1 4 5.3 CCOc1ccc(Sc2cc(C(=O)NC(C)CC)c3ccccc3n2)cc1 nan
16008956 23544 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 4.2 CCn1c(=O)c2cc(C(=O)NCCc3ccc(OC)c(OC)c3)sc2c2ccccc21 nan
CHEMBL1334014 23544 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 7 1 6 4.2 CCn1c(=O)c2cc(C(=O)NCCc3ccc(OC)c(OC)c3)sc2c2ccccc21 nan
2196864 23589 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 4.2 CCn1c(Cc2ccccc2)nnc1SCC(=O)Nc1nc2ccccc2s1 nan
CHEMBL1334332 23589 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 7 1 7 4.2 CCn1c(Cc2ccccc2)nnc1SCC(=O)Nc1nc2ccccc2s1 nan
3622707 23663 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2cccc(F)c2)c2oc3ccccc3c2n1 nan
CHEMBL1335007 23663 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 3 0 4 5.1 Cc1nc(SCc2cccc(F)c2)c2oc3ccccc3c2n1 nan
16008370 23689 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 4 3.7 Cn1c(=O)cc(SCC(=O)NCc2ccc(F)cc2)c2cc(Cl)ccc21 nan
CHEMBL1335160 23689 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 1 4 3.7 Cn1c(=O)cc(SCC(=O)NCc2ccc(F)cc2)c2cc(Cl)ccc21 nan
16020489 23728 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 5 3.7 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1cccc(C)c1)cn2C nan
CHEMBL1335441 23728 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 5 3.7 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1cccc(C)c1)cn2C nan
16012518 23732 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 5 5.3 CCOc1ccccc1NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccccc2)c1C nan
CHEMBL1335479 23732 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 5 5.3 CCOc1ccccc1NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccccc2)c1C nan
16018933 23739 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 7 2.8 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
CHEMBL1335514 23739 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 9 1 7 2.8 COc1ccc(OC)c(CCNC(=O)CCCn2c(=O)c3cccn3c3cccnc32)c1 nan
16022436 23750 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.2 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3nc2s1 nan
CHEMBL1335596 23750 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 2 7 5.2 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4Cl)cc3nc2s1 nan
3221114 23790 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 6 1 6 3.3 COCCN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)C1CCCC1 nan
CHEMBL1335947 23790 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 6 1 6 3.3 COCCN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)C1CCCC1 nan
16015039 23807 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccccc1NC(=O)c1sc(-n2nc(C)c(Cc3ccc4c(c3)OCO4)c2C)nc1C nan
CHEMBL1336092 23807 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 5.4 CCc1ccccc1NC(=O)c1sc(-n2nc(C)c(Cc3ccc4c(c3)OCO4)c2C)nc1C nan
2138945 23831 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 3.5 O=C(Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1)c1ccc(F)cc1 nan
CHEMBL1336262 23831 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 4 1 5 3.5 O=C(Nc1nc2ccc(S(=O)(=O)N3CCCC3)cc2s1)c1ccc(F)cc1 nan
6220215 23888 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C\c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
CHEMBL1336784 23888 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 1 2 3 3.2 CC1=CC2=NC(=O)/C(=C\c3c(C)[nH]c4ccc(C)cc34)C(=N)N2O1 nan
16026936 23925 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 9 3.0 O=C(COc1ccccc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1337126 23925 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 0 9 3.0 O=C(COc1ccccc1)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
1486592 23977 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 1 7 1.7 COc1ccc(Nc2nc(N(C)C)oc(=O)c2C#N)cc1 nan
CHEMBL1337568 23977 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 4 1 7 1.7 COc1ccc(Nc2nc(N(C)C)oc(=O)c2C#N)cc1 nan
1485789 23998 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 2 4.3 O=C(c1ccc(F)cc1)c1ccc(-c2ccc(F)cc2)nc1 nan
CHEMBL1337770 23998 23 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 0 2 4.3 O=C(c1ccc(F)cc1)c1ccc(-c2ccc(F)cc2)nc1 nan
16033861 24032 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 8 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
CHEMBL1338096 24032 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 2 8 4.6 CCc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4cccs4)cc3nc2s1 nan
1265732 24084 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 4 5.4 O=C(Cn1c(S)nc(-c2ccccc2)c1-c1ccccc1)c1ccccc1 nan
CHEMBL1338427 24084 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 1 4 5.4 O=C(Cn1c(S)nc(-c2ccccc2)c1-c1ccccc1)c1ccccc1 nan
16026086 24141 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 7 2.3 Cc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1339014 24141 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 7 2.3 Cc1ccccc1NC(=O)c1cnc2sc(N3CCCC3)nn2c1=O nan
15944700 24350 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 2 5 4.4 O=C(Nc1cc(Cl)cc(Cl)c1)c1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1 nan
CHEMBL1340950 24350 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 4 2 5 4.4 O=C(Nc1cc(Cl)cc(Cl)c1)c1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1 nan
5069163 24365 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 7 2.9 COc1ccc(CNC(=O)CCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)cc1 nan
CHEMBL1341068 24365 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 2 7 2.9 COc1ccc(CNC(=O)CCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)cc1 nan
855559 24488 2 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 3.5 CCN(C(=O)c1ccco1)c1nnc(-c2ccc(OC)cc2)s1 nan
CHEMBL1342076 24488 2 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 5 0 6 3.5 CCN(C(=O)c1ccco1)c1nnc(-c2ccc(OC)cc2)s1 nan
3149126 24502 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 10 2 7 3.5 CCOCCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2ccccc2c1=O nan
CHEMBL1342207 24502 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 10 2 7 3.5 CCOCCCn1c(SCC(=O)Nc2ccc(NC(C)=O)cc2)nc2ccccc2c1=O nan
1086862 24521 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 7 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccc(OC)c(OC)c3)s2)cc1 nan
CHEMBL1342348 24521 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 7 1 7 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccc(OC)c(OC)c3)s2)cc1 nan
5443591 24560 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 8 1 6 3.8 CCOC(=O)/C(C#N)=C\c1ccc(OCC(=O)Nc2ccc(C)cc2C)c(OC)c1 nan
CHEMBL1342661 24560 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 8 1 6 3.8 CCOC(=O)/C(C#N)=C\c1ccc(OCC(=O)Nc2ccc(C)cc2C)c(OC)c1 nan
665611 24597 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 6 3.9 Cc1cc(-c2nnc3sc(-c4ccc(Cl)cc4Cl)nn23)[nH]n1 nan
CHEMBL1342889 24597 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 1 6 3.9 Cc1cc(-c2nnc3sc(-c4ccc(Cl)cc4Cl)nn23)[nH]n1 nan
5063932 24655 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 5 3.6 O=C(NCc1ccco1)c1ccc2c(=O)n(-c3ccccc3)c(=S)[nH]c2c1 nan
CHEMBL1343363 24655 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 2 5 3.6 O=C(NCc1ccco1)c1ccc2c(=O)n(-c3ccccc3)c(=S)[nH]c2c1 nan
2452051 24804 4 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 4.6 N#Cc1ccc(CSc2nnc(NC(=O)c3ccc4ncsc4c3)s2)cc1 nan
CHEMBL1344739 24804 4 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 8 4.6 N#Cc1ccc(CSc2nnc(NC(=O)c3ccc4ncsc4c3)s2)cc1 nan
2335388 24892 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 2 1 5 3.0 Cc1ccnc(NC(=O)c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)c1 nan
CHEMBL1345474 24892 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 2 1 5 3.0 Cc1ccnc(NC(=O)c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)c1 nan
666154 24893 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 6 4.2 Cc1ccc(-n2nc(C)c3c(-c4cccs4)c(C#N)c(N)nc32)cc1 nan
CHEMBL1345487 24893 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 2 1 6 4.2 Cc1ccc(-n2nc(C)c3c(-c4cccs4)c(C#N)c(N)nc32)cc1 nan
2040126 24898 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 2 6 2.6 Cc1ccc(/C=C2\SC(=S)N(CCC(=O)NNS(=O)(=O)c3ccccc3)C2=O)cc1 nan
CHEMBL1345551 24898 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 7 2 6 2.6 Cc1ccc(/C=C2\SC(=S)N(CCC(=O)NNS(=O)(=O)c3ccccc3)C2=O)cc1 nan
3185713 24971 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 10 3 8 3.1 CCc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NCC1CCCO1)c1ccc(N(C)C)cc1 nan
CHEMBL1346198 24971 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 10 3 8 3.1 CCc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NCC1CCCO1)c1ccc(N(C)C)cc1 nan
1409877 25033 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(NC(=O)COC(=O)c2ccc3c(c2)OCO3)c1C nan
CHEMBL1346710 25033 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 2.8 Cc1cccc(NC(=O)COC(=O)c2ccc3c(c2)OCO3)c1C nan
3846689 25051 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 6 2.4 COCc1nc2oc3ccc(F)cc3c(=O)c2cc1C(=O)OC nan
CHEMBL1346831 25051 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 6 2.4 COCc1nc2oc3ccc(F)cc3c(=O)c2cc1C(=O)OC nan
2813569 25100 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 6 3.3 O=C(COc1ncnc2cc(Cl)ccc12)c1ccc2c(c1)OCCO2 nan
CHEMBL1347186 25100 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 356 4 0 6 3.3 O=C(COc1ncnc2cc(Cl)ccc12)c1ccc2c(c1)OCCO2 nan
2426514 25161 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 1 0 5 2.6 Cc1cc(=O)n2nc(-c3ccccc3)sc2c1C#N nan
CHEMBL1347674 25161 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 1 0 5 2.6 Cc1cc(=O)n2nc(-c3ccccc3)sc2c1C#N nan
2950848 25234 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.2 COCc1cc(C)nc(SCC(=O)NC2CCCCC2C)c1C#N nan
CHEMBL1348333 25234 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 6 1 5 3.2 COCc1cc(C)nc(SCC(=O)NC2CCCCC2C)c1C#N nan
664720 25279 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 7 5.4 CC(C)c1nc2sc3c(NCc4ccco4)ncnc3c2c2c1COC(C)(C)C2 nan
CHEMBL1348840 25279 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 4 1 7 5.4 CC(C)c1nc2sc3c(NCc4ccco4)ncnc3c2c2c1COC(C)(C)C2 nan
780682 25384 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 3 3.8 C=CCn1c(NC(=O)c2ccc(C)cc2)nc2ccccc21 nan
CHEMBL1349635 25384 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 4 1 3 3.8 C=CCn1c(NC(=O)c2ccc(C)cc2)nc2ccccc21 nan
7157934 25495 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 1.6 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 nan
CHEMBL1350603 25495 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 4 2 5 1.6 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc(S(=O)(=O)N2CCCC2)cc1 nan
16194401 25596 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 2 6 2.8 CCOC(=O)N1CCC(NC(=O)c2cc3c(O)nc4ccccc4c3n2C)CC1 nan
CHEMBL1351462 25596 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 3 2 6 2.8 CCOC(=O)N1CCC(NC(=O)c2cc3c(O)nc4ccccc4c3n2C)CC1 nan
1433829 25728 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 5 1 5 2.5 COc1ccc2nc(SCC(=O)NC3CC3)c(C#N)cc2c1 nan
CHEMBL1352517 25728 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 5 1 5 2.5 COc1ccc2nc(SCC(=O)NC3CC3)c(C#N)cc2c1 nan
5112429 25761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 2 7 1.9 N#CCC(=O)NNc1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] nan
CHEMBL1352781 25761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 2 7 1.9 N#CCC(=O)NNc1c([N+](=O)[O-])cc(C(F)(F)F)cc1[N+](=O)[O-] nan
4850085 25792 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 2 8 2.8 CCOC(=O)c1sc2nc(C)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
CHEMBL1353043 25792 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 7 2 8 2.8 CCOC(=O)c1sc2nc(C)nc(NCCc3ccc(S(N)(=O)=O)cc3)c2c1C nan
3350830 25935 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 2 4 4.7 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(Cl)c1 nan
CHEMBL1354025 25935 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 2 4 4.7 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(Cl)c1 nan
16017542 25978 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 7 3.6 CCN(c1ccc(C)cc1C)S(=O)(=O)c1nnc(NC(=O)c2ccccc2OC)s1 nan
CHEMBL1354338 25978 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 7 1 7 3.6 CCN(c1ccc(C)cc1C)S(=O)(=O)c1nnc(NC(=O)c2ccccc2OC)s1 nan
3415736 25992 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 2 6 2.3 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(S(=O)(=O)N4CCCC4)cc23)c(OC)c1 nan
CHEMBL1354486 25992 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 7 2 6 2.3 COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(S(=O)(=O)N4CCCC4)cc23)c(OC)c1 nan
16008465 25999 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 4 4.5 Cc1nc2cc(-c3cccc(F)c3)nn2c(C)c1CCC(=O)NC1CCCCC1 nan
CHEMBL1354574 25999 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 1 4 4.5 Cc1nc2cc(-c3cccc(F)c3)nn2c(C)c1CCC(=O)NC1CCCCC1 nan
16008364 26000 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 1 4 5.0 Cc1ccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c(Br)c1 nan
CHEMBL1354597 26000 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 1 4 5.0 Cc1ccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c(Br)c1 nan
16034362 26002 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 9 1 9 2.1 CSCCC(NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
CHEMBL1354617 26002 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 9 1 9 2.1 CSCCC(NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)C(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 nan
16029590 26007 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 1 3 5.8 O=C(Nc1ccc(Br)cc1F)c1ccc2nc(CCc3ccccc3)oc2c1 nan
CHEMBL1354702 26007 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 1 3 5.8 O=C(Nc1ccc(Br)cc1F)c1ccc2nc(CCc3ccccc3)oc2c1 nan
16024765 26012 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 1 4 3.8 O=C(Cn1c(=O)c(C(F)(F)F)nc2ccccc21)Nc1cccc(Br)c1 nan
CHEMBL1354803 26012 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 3 1 4 3.8 O=C(Cn1c(=O)c(C(F)(F)F)nc2ccccc21)Nc1cccc(Br)c1 nan
16026345 26018 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 2.6 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)NC(C)C)c32)cc1 nan
CHEMBL1354863 26018 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 1 5 2.6 Cc1ccc(-n2nc(C)c3c(C)cc(=O)n(CC(=O)NC(C)C)c32)cc1 nan
7872437 26020 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 3 6 3.8 CC(=O)Nc1ccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCCC4)cc1 nan
CHEMBL1354869 26020 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 5 3 6 3.8 CC(=O)Nc1ccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCCC4)cc1 nan
2135022 26030 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.3 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(C)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1354981 26030 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 7 4.3 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(C)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
135416424 26033 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 3 2 6 4.8 Cc1ccc2oc(-c3cc(NC(=O)c4ccc5c(c4)OCCO5)cc(C)c3O)nc2c1 nan
CHEMBL1355004 26033 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 3 2 6 4.8 Cc1ccc2oc(-c3cc(NC(=O)c4ccc5c(c4)OCCO5)cc(C)c3O)nc2c1 nan
16019041 26052 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 6 3.2 CC(C)OCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1355237 26052 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 8 1 6 3.2 CC(C)OCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
135437043 26062 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 3 7 3.3 CCOc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1 nan
CHEMBL1355309 26062 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 3 7 3.3 CCOc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3[nH]nc(C)c3c2=N)cc1 nan
16011751 26067 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 7 3.3 CCOC(=O)c1ccc(NC(=O)CC(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1 nan
CHEMBL1355424 26067 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 2 7 3.3 CCOC(=O)c1ccc(NC(=O)CC(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)cc1 nan
16027630 26070 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1355500 26070 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 8 3.4 Cc1ccccc1OCC(=O)Nc1ccc(C(=O)OCc2cc(=O)n3ccsc3n2)cc1 nan
16025481 26075 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 3.4 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1355611 26075 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 6 1 7 3.4 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(C)S3(=O)=O)cc1 nan
16020103 26083 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 4.2 CCOc1ccc(CNC(=O)c2nn(-c3ccc(OC)cc3)c(=O)c3c2c2ccccc2n3C)cc1 nan
CHEMBL1355692 26083 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 7 4.2 CCOc1ccc(CNC(=O)c2nn(-c3ccc(OC)cc3)c(=O)c3c2c2ccccc2n3C)cc1 nan
16026942 26089 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1ccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)cc1 nan
CHEMBL1355764 26089 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 0 9 3.3 Cc1ccc(OCC(=O)OCc2cc(=O)n3nc(-c4cccs4)sc3n2)cc1 nan
16011703 26093 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 3.6 COc1ccc(CCNc2nc3ccc(Cl)cc3n3cnnc23)cc1OC nan
CHEMBL1355798 26093 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 7 3.6 COc1ccc(CCNc2nc3ccc(Cl)cc3n3cnnc23)cc1OC nan
16026082 26094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
CHEMBL1355799 26094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 4 1 7 2.6 CCc1ccc(NC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)cc1 nan
16027128 26121 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 3 0 4 4.6 Cc1cc(=O)n(Cc2cccc(Br)c2)c2c1c(C)nn2-c1ccccc1 nan
CHEMBL1356158 26121 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 3 0 4 4.6 Cc1cc(=O)n(Cc2cccc(Br)c2)c2c1c(C)nn2-c1ccccc1 nan
16020942 26129 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 3 5.4 CC(NC(=O)Cn1c(-c2cccs2)cc2cc(F)ccc21)c1ccccc1 nan
CHEMBL1356228 26129 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 3 5.4 CC(NC(=O)Cn1c(-c2cccs2)cc2cc(F)ccc21)c1ccccc1 nan
2869380 26146 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 2 3 5.9 O=C(Nc1sc2c(c1C(=O)Nc1ccccc1Cl)CCCC2)c1ccccc1F nan
CHEMBL1356452 26146 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 2 3 5.9 O=C(Nc1sc2c(c1C(=O)Nc1ccccc1Cl)CCCC2)c1ccccc1F nan
4802695 26152 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 3 5 2.2 O=C(COC(=O)c1cc(Cl)ccc1O)NC(=O)NCc1ccccc1 nan
CHEMBL1356574 26152 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 3 5 2.2 O=C(COC(=O)c1cc(Cl)ccc1O)NC(=O)NCc1ccccc1 nan
16015066 26159 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1nc(SCC(=O)Nc2ccccc2Cl)cc(-c2ccccc2)n1 nan
CHEMBL1356682 26159 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 5 1 4 4.8 Cc1nc(SCC(=O)Nc2ccccc2Cl)cc(-c2ccccc2)n1 nan
16018801 26173 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 2 7 1.0 NS(=O)(=O)c1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1356848 26173 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 2 7 1.0 NS(=O)(=O)c1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1 nan
24687225 26178 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 8 0 8 3.1 COc1cccc(COC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2N2CCOCC2)c1OC nan
CHEMBL1356898 26178 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 504 8 0 8 3.1 COc1cccc(COC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2N2CCOCC2)c1OC nan
16015534 26183 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 4.3 CCOC(=O)CSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
CHEMBL1357001 26183 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 6 4.3 CCOC(=O)CSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
15989556 26184 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 1 9 2.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1357013 26184 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 8 1 9 2.5 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3cc(OC)c(OC)cc32)cc1 nan
16025511 26198 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.0 CCN1c2ccccc2-c2nc(SCC(=O)Nc3cccc(C)c3C)ncc2S1(=O)=O nan
CHEMBL1357149 26198 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 454 5 1 6 4.0 CCN1c2ccccc2-c2nc(SCC(=O)Nc3cccc(C)c3C)ncc2S1(=O)=O nan
20903553 26216 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 6 3.0 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1357354 26216 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 6 3.0 COc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
16031127 26227 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.2 CSc1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
CHEMBL1357550 26227 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.2 CSc1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
1146087 26231 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 4.7 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(F)cc3)n2)cc1 nan
CHEMBL1357694 26231 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 5 4.7 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(F)cc3)n2)cc1 nan
16027571 26252 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 9 2.9 CS(=O)(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1358013 26252 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 6 1 9 2.9 CS(=O)(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16027432 26262 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 1 9 3.1 Cc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
CHEMBL1358125 26262 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 5 1 9 3.1 Cc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
16012175 26266 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 4.7 Cc1ccccc1Cn1c2ccccc2c2cnn(CC(=O)NCCc3ccc(Cl)cc3)c(=O)c21 nan
CHEMBL1358188 26266 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 1 5 4.7 Cc1ccccc1Cn1c2ccccc2c2cnn(CC(=O)NCCc3ccc(Cl)cc3)c(=O)c21 nan
16011822 26271 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.2 CCOc1ccc(NC(=O)C2CCN(c3nnc(-n4c(C)ccc4C)s3)CC2)cc1 nan
CHEMBL1358209 26271 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 7 4.2 CCOc1ccc(NC(=O)C2CCN(c3nnc(-n4c(C)ccc4C)s3)CC2)cc1 nan
16015787 26272 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 6 6.0 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(C)c(F)c4)oc4ccccc34)no2)cc1 nan
CHEMBL1358232 26272 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 6 6.0 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(C)c(F)c4)oc4ccccc34)no2)cc1 nan
16009454 26307 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 CC(Oc1ccccc1)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1358685 26307 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 7 1 7 3.7 CC(Oc1ccccc1)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
16022826 26329 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.7 CCOc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)cc1 nan
CHEMBL1358850 26329 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 1 7 4.7 CCOc1ccc(NC(=O)C2CCN(c3nnc(C)c4c(C)n(-c5ccccc5)nc34)CC2)cc1 nan
654435 26351 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 6 4.2 O=C(CSc1nc2ccccc2o1)Nc1nc2ccccc2s1 nan
CHEMBL1359027 26351 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 6 4.2 O=C(CSc1nc2ccccc2o1)Nc1nc2ccccc2s1 nan
16009817 26358 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 1 7 5.0 Brc1cccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)c1 nan
CHEMBL1359062 26358 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 4 1 7 5.0 Brc1cccc(-c2nnn3c2nc(NCc2ccc4c(c2)OCO4)c2ccccc23)c1 nan
16009648 26430 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 5 4.3 COc1ccc(Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1359678 26430 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 0 5 4.3 COc1ccc(Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16020569 26466 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 5 4.3 CCCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
CHEMBL1360010 26466 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 5 4.3 CCCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
135546909 26478 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 6 3.7 COc1ccc(CN2CCc3nc(SCC(=O)Nc4cc(C)cc(C)c4)[nH]c(=O)c3C2)cc1 nan
CHEMBL1360113 26478 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 7 2 6 3.7 COc1ccc(CN2CCc3nc(SCC(=O)Nc4cc(C)cc(C)c4)[nH]c(=O)c3C2)cc1 nan
3185716 26502 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 10 3 8 3.7 CC(C)c1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)cc1 nan
CHEMBL1360292 26502 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 564 10 3 8 3.7 CC(C)c1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)cc1 nan
2819025 26521 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 1 1 5 1.9 N#Cc1cnc2cc(-c3ccccc3)nn2c1N nan
CHEMBL1360465 26521 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 235 1 1 5 1.9 N#Cc1cnc2cc(-c3ccccc3)nn2c1N nan
2141195 26542 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.7 CCc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccccc1)cn2CC(=O)Nc1cc(C)ccc1C nan
CHEMBL1360707 26542 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 5 4.7 CCc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccccc1)cn2CC(=O)Nc1cc(C)ccc1C nan
135436940 26544 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 7 5.0 Oc1cc(-c2ccc(F)cc2)nc(SCc2nc(-c3cccc(Cl)c3)no2)n1 nan
CHEMBL1360713 26544 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 7 5.0 Oc1cc(-c2ccc(F)cc2)nc(SCc2nc(-c3cccc(Cl)c3)no2)n1 nan
16009483 26563 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 9 1 7 1.4 CCCCN(C)CCNC(=O)C1CCCN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)C1 nan
CHEMBL1360843 26563 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 9 1 7 1.4 CCCCN(C)CCNC(=O)C1CCCN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)C1 nan
2135565 26614 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3ccc(F)cc3c2=O)cc1 nan
CHEMBL1361368 26614 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc4c(c3)OCCO4)c3ccc(F)cc3c2=O)cc1 nan
7598414 26676 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1cccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)c1 nan
CHEMBL1361891 26676 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 4 1 5 2.8 Cc1cccc(Cn2cccc(C(=O)Nc3cc(C)on3)c2=O)c1 nan
1071174 26678 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 8 1 7 3.8 CCOc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3ccccc3c2=O)cc1 nan
CHEMBL1361894 26678 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 8 1 7 3.8 CCOc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3ccccc3c2=O)cc1 nan
857565 26743 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 4.2 Cc1cc(NC(=O)CSc2nc3c(C)c(C)ccc3cc2C)no1 nan
CHEMBL1362451 26743 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 4.2 Cc1cc(NC(=O)CSc2nc3c(C)c(C)ccc3cc2C)no1 nan
790083 26842 58 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 0 4 4.2 COc1ccccc1-c1nc(-c2ccc(Br)cc2)no1 nan
CHEMBL1363291 26842 58 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 0 4 4.2 COc1ccccc1-c1nc(-c2ccc(Br)cc2)no1 nan
2137970 26901 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3ccccc3)c3ccc(Cl)cc3c2=O)cc1 nan
CHEMBL1363852 26901 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 6 4.1 COc1ccc(S(=O)(=O)c2cn(CC(=O)Nc3ccccc3)c3ccc(Cl)cc3c2=O)cc1 nan
22522543 26950 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 1 4 3.2 Cc1ccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)cc1 nan
CHEMBL1364334 26950 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 331 3 1 4 3.2 Cc1ccc(NC(=O)Cn2c(=O)c3cccn3c3ccccc32)cc1 nan
1581690 26991 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 10 2 6 4.6 CCCCCOc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cc(C)on3)cc2)cc1 nan
CHEMBL1364631 26991 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 10 2 6 4.6 CCCCCOc1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cc(C)on3)cc2)cc1 nan
1759638 27019 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 5 1 5 5.3 Cc1c(CCC(=O)N2CCC(C(=O)O)(c3ccccc3)CC2)c(=O)oc2cc3oc4c(c3cc12)CCCC4 nan
CHEMBL1364853 27019 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 513 5 1 5 5.3 Cc1c(CCC(=O)N2CCC(C(=O)O)(c3ccccc3)CC2)c(=O)oc2cc3oc4c(c3cc12)CCCC4 nan
2137118 27121 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 1 6 4.2 COc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccc(F)cc1)cn2CC(=O)Nc1ccc(C)cc1C nan
CHEMBL1365673 27121 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 1 6 4.2 COc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccc(F)cc1)cn2CC(=O)Nc1ccc(C)cc1C nan
16008395 27147 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 6 3.7 CCn1c(=O)cc(OCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2ccccc21 nan
CHEMBL1365942 27147 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 6 3.7 CCn1c(=O)cc(OCC(=O)Nc2cc(Cl)c(OC)cc2OC)c2ccccc21 nan
2155747 27156 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 7 1 8 3.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)cc1 nan
CHEMBL1366006 27156 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 7 1 8 3.2 CCOc1ccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)cc1 nan
16012964 27158 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 3 5.0 CCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
CHEMBL1366015 27158 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 3 5.0 CCCN(Cc1cc2cc(C)ccc2nc1O)C(=O)c1cccc(Cl)c1 nan
2474394 27210 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 3.5 CCCn1c(=O)[nH]c(=O)c2c(C(F)(F)F)cc(-c3ccc(C)cc3)nc21 nan
CHEMBL1366444 27210 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 3 1 4 3.5 CCCn1c(=O)[nH]c(=O)c2c(C(F)(F)F)cc(-c3ccc(C)cc3)nc21 nan
17757029 27242 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 0 8 4.6 CCOC(=O)COc1ccc([N+](=O)[O-])cc1-c1ccnc2cc(-c3ccc(Cl)cc3)nn12 nan
CHEMBL1366773 27242 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 0 8 4.6 CCOC(=O)COc1ccc([N+](=O)[O-])cc1-c1ccnc2cc(-c3ccc(Cl)cc3)nn12 nan
5087310 27394 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 7 2.8 COc1cc2c(cc1OC)n(CC(=O)NC1CCCCCC1)n1c(C)cc(=O)nc21 nan
CHEMBL1367963 27394 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 412 5 1 7 2.8 COc1cc2c(cc1OC)n(CC(=O)NC1CCCCCC1)n1c(C)cc(=O)nc21 nan
4825943 27403 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 2.8 CC(Sc1nc2ccccc2c(=O)n1C)C(=O)Nc1ccc2c(c1)OCCO2 nan
CHEMBL1368013 27403 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 7 2.8 CC(Sc1nc2ccccc2c(=O)n1C)C(=O)Nc1ccc2c(c1)OCCO2 nan
16022825 27423 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 10 1.9 Cc1ccc(C)c(NC(=O)Cn2c(=O)n(Cc3nc(C)no3)c(=O)c3cc4c(cc32)OCO4)c1 nan
CHEMBL1368194 27423 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 5 1 10 1.9 Cc1ccc(C)c(NC(=O)Cn2c(=O)n(Cc3nc(C)no3)c(=O)c3cc4c(cc32)OCO4)c1 nan
709853 27466 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.7 COc1ccc(CNC(=O)c2cc3cccc(OC)c3oc2=O)cc1 nan
CHEMBL1368522 27466 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.7 COc1ccc(CNC(=O)c2cc3cccc(OC)c3oc2=O)cc1 nan
16019023 27486 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 8 1 6 2.9 CCOCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1368698 27486 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 8 1 6 2.9 CCOCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
1898787 27501 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 1.9 COC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
CHEMBL1368847 27501 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 8 1.9 COC(=O)CSc1nc(N)c(C#N)c(-c2ccco2)c1C#N nan
16746213 27515 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 11 3 5 4.4 NC(=O)CC(NC(=O)Cc1ccc(Br)cc1)c1ccc(NCCc2ccccc2F)c([N+](=O)[O-])c1 nan
CHEMBL1368944 27515 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 542 11 3 5 4.4 NC(=O)CC(NC(=O)Cc1ccc(Br)cc1)c1ccc(NCCc2ccccc2F)c([N+](=O)[O-])c1 nan
15989069 27517 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 12 1 9 2.7 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
CHEMBL1368950 27517 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 528 12 1 9 2.7 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccc3c(c2)OCO3)c(=O)c2sccc21 nan
3417357 27557 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 0 6 4.9 Cc1cc(C)c(Cn2c(=O)n(-c3ccccc3Cl)c(=O)c3c(C)c(C(=O)N(C)C)sc32)c(C)c1 nan
CHEMBL1369202 27557 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 0 6 4.9 Cc1cc(C)c(Cn2c(=O)n(-c3ccccc3Cl)c(=O)c3c(C)c(C(=O)N(C)C)sc32)c(C)c1 nan
4454678 27585 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 4.4 Cc1cc(OCC(=O)Nc2cc(-c3nn4c(C)nnc4s3)ccc2C)ccc1Cl nan
CHEMBL1369422 27585 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 4.4 Cc1cc(OCC(=O)Nc2cc(-c3nn4c(C)nnc4s3)ccc2C)ccc1Cl nan
16034378 27663 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 7 1 4 3.5 COc1ccc(C(=O)CCC(=O)Nc2cccc(C(C)=O)c2)cc1 nan
CHEMBL1369934 27663 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 7 1 4 3.5 COc1ccc(C(=O)CCC(=O)Nc2cccc(C(C)=O)c2)cc1 nan
16746462 27685 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 8 1 6 3.3 COc1cc(O)c(C(CCN2CCOCC2)c2ccc(N(C)C)cc2)c(OC)c1 nan
CHEMBL1370067 27685 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 8 1 6 3.3 COc1cc(O)c(C(CCN2CCOCC2)c2ccc(N(C)C)cc2)c(OC)c1 nan
3236293 27687 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 8 3.3 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccsc2c1=O nan
CHEMBL1370078 27687 9 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 7 1 8 3.3 CCCCn1c(SCC(=O)Nc2cc(C)on2)nc2ccsc2c1=O nan
5310561 27739 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.8 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccc(F)cc3)c2n1 nan
CHEMBL1370473 27739 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 2 7 2.8 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccc(F)cc3)c2n1 nan
667326 27752 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 5 3.5 CCOCCCNc1ncc2c(n1)CC(c1ccc(C)cc1)CC2=O nan
CHEMBL1370544 27752 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 7 1 5 3.5 CCOCCCNc1ncc2c(n1)CC(c1ccc(C)cc1)CC2=O nan
135546918 27765 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 3.6 CCCN1CCc2nc(SCC(=O)Nc3ccc(C)c(Cl)c3)nc(O)c2C1 nan
CHEMBL1370635 27765 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 3.6 CCCN1CCc2nc(SCC(=O)Nc3ccc(C)c(Cl)c3)nc(O)c2C1 nan
3628612 27796 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.4 CCc1nc(SCC(=O)NCCc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1370855 27796 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 7 1 5 4.4 CCc1nc(SCC(=O)NCCc2ccccc2)c2oc3ccccc3c2n1 nan
1348188 27942 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1cccc(-c2nc3cc(NC(=O)Cc4ccc(Cl)cc4)ccc3o2)c1 nan
CHEMBL1372034 27942 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1cccc(-c2nc3cc(NC(=O)Cc4ccc(Cl)cc4)ccc3o2)c1 nan
1854798 27967 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 1 0 5 3.6 Cn1c(=O)nc2n(-c3ccc(Br)cc3)c3cccc(Cl)c3cc-2c1=O nan
CHEMBL1372184 27967 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 1 0 5 3.6 Cn1c(=O)nc2n(-c3ccc(Br)cc3)c3cccc(Cl)c3cc-2c1=O nan
16019423 28038 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 9 5.0 CC(C)c1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1372659 28038 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 6 1 9 5.0 CC(C)c1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
16031591 28099 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 6 3.4 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc(-c4coc(C)n4)cc3)CC2)cc1 nan
CHEMBL1373010 28099 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 6 3.4 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc(-c4coc(C)n4)cc3)CC2)cc1 nan
2684697 28174 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 COc1ccc(C)cc1NC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3 nan
CHEMBL1373515 28174 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 3 1 5 3.7 COc1ccc(C)cc1NC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3 nan
652717 28190 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 5 5.1 CCN1CCCC1CN(Cc1cc2cc(C)cc(C)c2nc1O)C(=O)Nc1ccccc1OC nan
CHEMBL1373605 28190 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 7 2 5 5.1 CCN1CCCC1CN(Cc1cc2cc(C)cc(C)c2nc1O)C(=O)Nc1ccccc1OC nan
16015413 28201 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
CHEMBL1373657 28201 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 1 6 6.2 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(F)cc3)cc2s1 nan
16033161 28237 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 2 5 4.6 O=C(Nc1ccc(N2CCN(CCOc3ccc(Cl)cc3)CC2)c(C(=O)O)c1)c1ccc(F)cc1 nan
CHEMBL1373926 28237 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 2 5 4.6 O=C(Nc1ccc(N2CCN(CCOc3ccc(Cl)cc3)CC2)c(C(=O)O)c1)c1ccc(F)cc1 nan
16030696 28243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 2.9 CC(=O)c1ccc(NC(=O)CSc2nc(-c3ccccc3C)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1374004 28243 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 1 9 2.9 CC(=O)c1ccc(NC(=O)CSc2nc(-c3ccccc3C)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
15997814 28288 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 6 4.2 COc1cc2nc(S)nc(NCc3cccc(Cl)c3)c2cc1OC nan
CHEMBL1374312 28288 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 6 4.2 COc1cc2nc(S)nc(NCc3cccc(Cl)c3)c2cc1OC nan
4521283 28296 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 4 1 5 4.7 O=C(CN1C(=O)c2ccccc2Sc2ccc(C(=O)N3CCOCC3)cc21)Nc1ccc(Cl)cc1F nan
CHEMBL1374381 28296 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 525 4 1 5 4.7 O=C(CN1C(=O)c2ccccc2Sc2ccc(C(=O)N3CCOCC3)cc21)Nc1ccc(Cl)cc1F nan
3734127 28334 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 4 4.0 CCc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1 nan
CHEMBL1374637 28334 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 4 4.0 CCc1ccc(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)cc1 nan
669593 28349 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 1 5 2.1 O=C(Nc1nccs1)c1ccc2c(c1)OCO2 nan
CHEMBL1374723 28349 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 248 2 1 5 2.1 O=C(Nc1nccs1)c1ccc2c(c1)OCO2 nan
656234 28390 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 3.3 O=c1c2ccccc2nc(CSc2[nH]cnc3ncnc2-3)n1-c1ccccc1 nan
CHEMBL1375001 28390 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 1 7 3.3 O=c1c2ccccc2nc(CSc2[nH]cnc3ncnc2-3)n1-c1ccccc1 nan
4074625 28404 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 3 6 0.3 COC(=O)c1ccccc1NC=C1C(=O)NC(=S)NC1=O nan
CHEMBL1375120 28404 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 3 3 6 0.3 COC(=O)c1ccccc1NC=C1C(=O)NC(=S)NC1=O nan
828451 28504 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 1 4 4.6 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 nan
CHEMBL1375831 28504 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 4 1 4 4.6 CCOc1ccc(Nc2nc3c(C)cccc3cc2C#N)cc1 nan
7246250 28509 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 3 0 5 3.4 COc1cc(Br)cc2cc(S(=O)(=O)c3ccccc3)c(=O)oc12 nan
CHEMBL1375897 28509 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 3 0 5 3.4 COc1cc(Br)cc2cc(S(=O)(=O)c3ccccc3)c(=O)oc12 nan
16029523 28531 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 0 6 2.3 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3ccc(F)cc3)CC1)CCS2 nan
CHEMBL1376205 28531 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 5 0 6 2.3 CN(C)S(=O)(=O)c1ccc2c(c1)N(CC(=O)N1CCN(c3ccc(F)cc3)CC1)CCS2 nan
4048244 28559 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 13 1 8 4.1 CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1 nan
CHEMBL1376427 28559 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 546 13 1 8 4.1 CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1 nan
1629947 28598 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 4 1.6 O=C1NC(=S)NC(=O)C1=Cc1ccc2c(c1)CCN2CCCCl nan
CHEMBL1376754 28598 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 2 4 1.6 O=C1NC(=S)NC(=O)C1=Cc1ccc2c(c1)CCN2CCCCl nan
1281315 28614 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 2 6 6.1 COc1ccc(-c2c3c(nc4sc(C(=O)Nc5ccccc5F)c(N)c24)CC(C)(C)CC3=O)cc1 nan
CHEMBL1376941 28614 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 2 6 6.1 COc1ccc(-c2c3c(nc4sc(C(=O)Nc5ccccc5F)c(N)c24)CC(C)(C)CC3=O)cc1 nan
3640458 28638 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 1 7 3.6 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C)C2 nan
CHEMBL1377235 28638 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 1 7 3.6 CCOC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCC(C)CC3)cc2)sc2c1CCN(C)C2 nan
4307577 28674 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 10 2 4 6.4 CC(C)c1ccc(Nc2cc(C(=O)NCCCN(C)Cc3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1377592 28674 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 10 2 4 6.4 CC(C)c1ccc(Nc2cc(C(=O)NCCCN(C)Cc3ccccc3)c3ccccc3n2)cc1 nan
16193746 28755 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 1 6 2.3 Cc1ccc(N2C(=O)C3C4C=CC(CN=C(S)N5CCN(c6ccccn6)CC5)(O4)C3C2=O)cc1 nan
CHEMBL1378295 28755 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 4 1 6 2.3 Cc1ccc(N2C(=O)C3C4C=CC(CN=C(S)N5CCN(c6ccccn6)CC5)(O4)C3C2=O)cc1 nan
2220966 28797 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 3 3.4 Cc1c(Cl)ccc2c(C(N)=O)cc(-c3ccccn3)nc12 nan
CHEMBL1378741 28797 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 1 3 3.4 Cc1c(Cl)ccc2c(C(N)=O)cc(-c3ccccn3)nc12 nan
7422753 28812 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 4 2.2 NC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3)c2=O)cc1 nan
CHEMBL1378862 28812 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 5 2 4 2.2 NC(=O)c1ccc(NC(=O)c2cccn(Cc3ccccc3)c2=O)cc1 nan
2815317 28820 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.8 Cc1cc(C)c2c(n1)sc1c(=O)n(Cc3ccc(F)cc3)cnc12 nan
CHEMBL1378935 28820 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 2 0 5 3.8 Cc1cc(C)c2c(n1)sc1c(=O)n(Cc3ccc(F)cc3)cnc12 nan
16193948 28836 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 3.5 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(c2ccccn2)CC1 nan
CHEMBL1379050 28836 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 3.5 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(c2ccccn2)CC1 nan
24746968 28957 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.1 Cc1nc(Nc2ccccc2F)c2nnn(Cc3ccccc3Cl)c2n1 nan
CHEMBL1380147 28957 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 1 6 4.1 Cc1nc(Nc2ccccc2F)c2nnn(Cc3ccccc3Cl)c2n1 nan
725312 28980 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 3.0 CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O nan
CHEMBL1380313 28980 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 1 6 3.0 CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O nan
24792708 29013 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 7 3.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)c3ccccc3F)s2)cc1 nan
CHEMBL1380537 29013 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 2 7 3.3 COc1ccc(CNC(=O)CSc2nnc(NC(=O)c3ccccc3F)s2)cc1 nan
3604840 29043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
CHEMBL1380782 29043 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 4 1 5 3.7 COc1cccc(-c2cc(C(=O)Nc3cccnc3Cl)no2)c1 nan
1980822 29196 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 4 3.9 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C)n2)cc1 nan
CHEMBL1382084 29196 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 5 2 4 3.9 COc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C)n2)cc1 nan
555289 29256 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 4 3.6 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C)n1 nan
CHEMBL1382619 29256 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 4 1 4 3.6 Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C)n1 nan
9550495 29452 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccc(-c2nc3ncccc3o2)cc1NC(=O)COc1ccccc1 nan
CHEMBL1384380 29452 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 5 4.2 Cc1ccc(-c2nc3ncccc3o2)cc1NC(=O)COc1ccccc1 nan
7161160 29469 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 7 0.3 CCOc1ccccc1NS(=O)(=O)c1cn(C)c(=O)n(C)c1=O nan
CHEMBL1384530 29469 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 7 0.3 CCOc1ccccc1NS(=O)(=O)c1cn(C)c(=O)n(C)c1=O nan
4271811 29524 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 0 5 3.2 CCCc1nc2ccccc2c(=O)n1CC(=O)c1ccc(OC)cc1 nan
CHEMBL1384958 29524 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 6 0 5 3.2 CCCc1nc2ccccc2c(=O)n1CC(=O)c1ccc(OC)cc1 nan
2123263 29533 7 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 9 3.5 CCCn1c(N)c(-c2nc(C3CCCC3)c(C(=O)c3ccc(NC(C)=O)cc3)s2)c(=O)n(C)c1=O nan
CHEMBL1385062 29533 7 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 7 2 9 3.5 CCCn1c(N)c(-c2nc(C3CCCC3)c(C(=O)c3ccc(NC(C)=O)cc3)s2)c(=O)n(C)c1=O nan
3243476 29579 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 3.4 CC(=O)Nc1nc2c(c3c1c(=O)oc1ccccc13)CC(C)CC2 nan
CHEMBL1385469 29579 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 322 1 1 4 3.4 CC(=O)Nc1nc2c(c3c1c(=O)oc1ccccc13)CC(C)CC2 nan
645034 29631 4 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.9 N#Cc1cc2cc3c(cc2nc1N1CCCCC1)OCCO3 nan
CHEMBL1385946 29631 4 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 1 0 5 2.9 N#Cc1cc2cc3c(cc2nc1N1CCCCC1)OCCO3 nan
1233014 29652 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.4 Cc1ccc(C#N)c(SCC(=O)Nc2nccs2)n1 nan
CHEMBL1386142 29652 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 4 1 6 2.4 Cc1ccc(C#N)c(SCC(=O)Nc2nccs2)n1 nan
818106 29680 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 4 4.0 COc1ccc(-c2nc3c4ccccc4ccn3c2C=O)cc1 nan
CHEMBL1386316 29680 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 3 0 4 4.0 COc1ccc(-c2nc3c4ccccc4ccn3c2C=O)cc1 nan
2803005 29683 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.8 NC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
CHEMBL1386328 29683 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 2 3.8 NC(=O)c1cc(-c2ccccc2)nc2ccc(Br)cc12 nan
743778 29717 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 3 3.2 Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1 nan
CHEMBL1386595 29717 13 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 243 1 1 3 3.2 Cc1cc(-c2ccc(Cl)cc2)c(C#N)c(N)n1 nan
1078300 29721 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3cccc(C)c3)c(=O)c2c1C nan
CHEMBL1386617 29721 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3cccc(C)c3)c(=O)c2c1C nan
2197659 29774 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.6 COc1ccc2c(c1)c(=O)oc1cc(OCC(=O)NC3CC3)ccc12 nan
CHEMBL1387003 29774 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 1 5 2.6 COc1ccc2c(c1)c(=O)oc1cc(OCC(=O)NC3CC3)ccc12 nan
2368754 29796 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 0 4 2.1 CCN1C(=O)C(=C2C=C(C)OC(C)=C2)C(=O)N(CC)C1=S nan
CHEMBL1387204 29796 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 0 4 2.1 CCN1C(=O)C(=C2C=C(C)OC(C)=C2)C(=O)N(CC)C1=S nan
1590813 29841 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 1 5.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc(-c2ccccc2)cc1 nan
CHEMBL1387594 29841 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 1 5.9 O=C(Nc1ccc(Cl)cc1Cl)c1ccc(-c2ccccc2)cc1 nan
16194196 29854 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 8 2.6 CCOC(=O)N1CCN(C(=O)CCCCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)CC1 nan
CHEMBL1387679 29854 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 8 2.6 CCOC(=O)N1CCN(C(=O)CCCCCn2c(=S)[nH]c3cc4c(cc3c2=O)OCO4)CC1 nan
3961803 29876 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 8 -0.6 Cn1nc(C(=O)OCC(=O)NC2CCS(=O)(=O)C2)c2ccccc2c1=O nan
CHEMBL1387823 29876 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 8 -0.6 Cn1nc(C(=O)OCC(=O)NC2CCS(=O)(=O)C2)c2ccccc2c1=O nan
649021 29925 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.8 Cc1cccc2cc(C(c3nnnn3Cc3ccc4c(c3)OCO4)N3CCC(C)CC3)c(O)nc12 nan
CHEMBL1388237 29925 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.8 Cc1cccc2cc(C(c3nnnn3Cc3ccc4c(c3)OCO4)N3CCC(C)CC3)c(O)nc12 nan
2565451 29942 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 2.1 CCOC(=O)c1sc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)nc1C nan
CHEMBL1388388 29942 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 7 2.1 CCOC(=O)c1sc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)nc1C nan
20874214 29969 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 3.7 CC(C)c1nn2c(=O)cc(COc3cccc(NC(=O)c4ccco4)c3)nc2s1 nan
CHEMBL1388517 29969 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 6 1 8 3.7 CC(C)c1nn2c(=O)cc(COc3cccc(NC(=O)c4ccco4)c3)nc2s1 nan
736044 30028 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 2 5 1.3 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 nan
CHEMBL1389015 30028 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 3 2 5 1.3 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 nan
3581200 30097 4 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 5 4.9 O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(OCC2CCCO2)cc1 nan
CHEMBL1389543 30097 4 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 1 5 4.9 O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(OCC2CCCO2)cc1 nan
2815149 30213 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 1 0 4 3.3 Cn1c2ccccc2n2c(=O)cc(-c3ccccc3)c(C#N)c12 nan
CHEMBL1390567 30213 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 1 0 4 3.3 Cn1c2ccccc2n2c(=O)cc(-c3ccccc3)c(C#N)c12 nan
1480454 30359 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 5 3.1 CN(C)c1nc(-c2cccnc2)nc(-c2ccccc2)c1C#N nan
CHEMBL1391874 30359 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 0 5 3.1 CN(C)c1nc(-c2cccnc2)nc(-c2ccccc2)c1C#N nan
3151961 30369 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 6 2.6 CC(C)c1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 nan
CHEMBL1391972 30369 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 291 3 1 6 2.6 CC(C)c1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 nan
2818919 30510 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 5 5.2 FC(F)(F)c1cc(-c2cccs2)nc2cc(-c3cccs3)nn12 nan
CHEMBL1393159 30510 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 0 5 5.2 FC(F)(F)c1cc(-c2cccs2)nc2cc(-c3cccs3)nn12 nan
3597887 30517 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 4.2 Cc1ccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(SCC(=O)NCC3CCCO3)o2)cc1 nan
CHEMBL1393192 30517 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 7 4.2 Cc1ccc(-c2nc(S(=O)(=O)c3ccc(C)cc3)c(SCC(=O)NCC3CCCO3)o2)cc1 nan
6498520 30567 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 6 2.9 CN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)CC(C)(C)CN(C)C nan
CHEMBL1393589 30567 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 6 1 6 2.9 CN=C(S)N(Cc1cc2cc(C)ccc2n2nnnc12)CC(C)(C)CN(C)C nan
938851 30600 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 1 5 3.7 Cc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
CHEMBL1393863 30600 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 1 5 3.7 Cc1ccc2nc(O)c(COC(=O)c3cccs3)cc2c1 nan
2810066 30610 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 2.9 COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC nan
CHEMBL1393944 30610 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 2.9 COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC nan
16010814 30622 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 3 0 7 4.3 Clc1cccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)c1 nan
CHEMBL1394069 30622 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 3 0 7 4.3 Clc1cccc(N2CCN(c3nc4ccccc4c4nc(-c5cccnc5)nn34)CC2)c1 nan
16018745 30636 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 3 5.9 Cc1ccc(Cn2c(C(=O)O)c(CNCc3ccccc3Cl)c3ccc(C)cc32)cc1 nan
CHEMBL1394183 30636 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 2 3 5.9 Cc1ccc(Cn2c(C(=O)O)c(CNCc3ccccc3Cl)c3ccc(C)cc32)cc1 nan
16030321 30637 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 3.8 COc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
CHEMBL1394221 30637 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 6 3.8 COc1ccccc1C(=O)Nc1ccc(OCc2cc(=O)n3cccc(C)c3n2)cc1 nan
16019476 30639 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 4.4 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
CHEMBL1394231 30639 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 9 4.4 CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCc2cccs2)c2sccc23)cc1 nan
16012300 30644 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1ccc(NC(=O)c2ccc(-c3ccccc3)s2)cc1 nan
CHEMBL1394287 30644 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 293 3 1 2 5.0 Cc1ccc(NC(=O)c2ccc(-c3ccccc3)s2)cc1 nan
16015419 30675 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 8 1 6 6.3 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(C)cc3)cc2s1 nan
CHEMBL1394800 30675 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 8 1 6 6.3 COc1cc(C)ccc1OCCSc1nc2ccc(NC(=O)c3ccc(C)cc3)cc2s1 nan
5297365 30684 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1cccc(C(F)(F)F)c1)C1CCN2CC1 nan
CHEMBL1394905 30684 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 5 4.4 N#Cc1cc2c(nc1SCC(=O)Nc1cccc(C(F)(F)F)c1)C1CCN2CC1 nan
1308289 30685 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 0 6 4.2 CCS(=O)(=O)c1c(S(=O)(=O)CC)c2cc(C(C)(C)C)ccn2c1C(=O)c1ccc(F)cc1 nan
CHEMBL1394907 30685 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 0 6 4.2 CCS(=O)(=O)c1c(S(=O)(=O)CC)c2cc(C(C)(C)C)ccn2c1C(=O)c1ccc(F)cc1 nan
7338094 30700 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1ccn2c(Nc3ccccc3C)c(-c3ccc(N4CCOCC4)cc3)nc2c1 nan
CHEMBL1395018 30700 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 5 5.2 Cc1ccn2c(Nc3ccccc3C)c(-c3ccc(N4CCOCC4)cc3)nc2c1 nan
1598875 30702 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 7 3.4 COC(=O)c1ccccc1NC(=O)CSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 nan
CHEMBL1395042 30702 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 2 7 3.4 COC(=O)c1ccccc1NC(=O)CSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 nan
705204 30712 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 1 1 5 3.7 N#Cc1c(N)n(-c2cccc(Cl)c2)c2nc3ccccc3nc12 nan
CHEMBL1395126 30712 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 1 1 5 3.7 N#Cc1c(N)n(-c2cccc(Cl)c2)c2nc3ccccc3nc12 nan
16011870 30718 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 6 6.9 Cc1oc(-c2ccccc2F)nc1Cn1c(SCc2cccc(C(F)(F)F)c2)nc2ccncc21 nan
CHEMBL1395173 30718 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 6 0 6 6.9 Cc1oc(-c2ccccc2F)nc1Cn1c(SCc2cccc(C(F)(F)F)c2)nc2ccncc21 nan
16011750 30719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 4.2 CCC(C(=O)NCc1cc(OC)ccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1395174 30719 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 7 1 7 4.2 CCC(C(=O)NCc1cc(OC)ccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
7150993 30721 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 Cc1ccc2nc(NC(=O)CSc3nccn3Cc3ccccc3)sc2c1 nan
CHEMBL1395184 30721 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 4.6 Cc1ccc2nc(NC(=O)CSc3nccn3Cc3ccccc3)sc2c1 nan
16022376 30747 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 4.7 O=C(CSc1nc2ccsc2c(=O)n1Cc1ccc(F)cc1)NCc1ccc(Cl)cc1 nan
CHEMBL1395536 30747 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 7 1 6 4.7 O=C(CSc1nc2ccsc2c(=O)n1Cc1ccc(F)cc1)NCc1ccc(Cl)cc1 nan
16008365 30774 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.9 COc1cccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c1 nan
CHEMBL1395994 30774 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 5 3.9 COc1cccc(NC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)c1 nan
16016520 30782 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 2 2 3.4 Cc1cccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)c1 nan
CHEMBL1396103 30782 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 2 2 3.4 Cc1cccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)c1 nan
16012961 30804 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 3.2 COc1ccc(Cc2nc3c4cnn(-c5cccc(F)c5)c4ncn3n2)cc1 nan
CHEMBL1396439 30804 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 0 7 3.2 COc1ccc(Cc2nc3c4cnn(-c5cccc(F)c5)c4ncn3n2)cc1 nan
16011203 30824 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 3.8 CCc1nn(CC(=O)Nc2c(C)cc(C)cc2C)c(=O)c2cc3sccc3n12 nan
CHEMBL1396725 30824 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 4 1 6 3.8 CCc1nn(CC(=O)Nc2c(C)cc(C)cc2C)c(=O)c2cc3sccc3n12 nan
5300039 30848 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 2 5 4.7 Nc1c(C(=O)Nc2ccc(Br)cc2F)sc2nc3c(cc12)N1CCC3CC1 nan
CHEMBL1397016 30848 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 2 2 5 4.7 Nc1c(C(=O)Nc2ccc(Br)cc2F)sc2nc3c(cc12)N1CCC3CC1 nan
16029565 30862 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 4.0 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(F)ccc32)c1 nan
CHEMBL1397193 30862 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 4.0 Cc1ccc(C)c(NC(=O)Cn2cc(C(=O)c3ccncc3)c(=O)c3cc(F)ccc32)c1 nan
9114471 30875 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 7 1.5 N#Cc1cc(C#N)c(SCC(=O)N2CC(=O)Nc3ccccc32)nc1N nan
CHEMBL1397378 30875 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 3 2 7 1.5 N#Cc1cc(C#N)c(SCC(=O)N2CC(=O)Nc3ccccc32)nc1N nan
16029539 30879 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 5 4.7 Cc1ccc2c(c1)c(=O)c(C(=O)c1ccncc1)cn2CC(=O)Nc1ccc(C(C)C)cc1 nan
CHEMBL1397433 30879 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 5 4.7 Cc1ccc2c(c1)c(=O)c(C(=O)c1ccncc1)cn2CC(=O)Nc1ccc(C(C)C)cc1 nan
16021836 30882 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.1 CSc1ncc(C(=O)NCc2ccc(C)cc2)c(-c2ccccc2)n1 nan
CHEMBL1397498 30882 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 4.1 CSc1ncc(C(=O)NCc2ccc(C)cc2)c(-c2ccccc2)n1 nan
16024513 30884 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C)cc3Cl)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1397525 30884 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 5 1 5 4.8 Cc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(C)cc3Cl)c3nc(C)ccc3c2=O)cc1 nan
4069971 30910 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 4 5.3 CCCCNC(=O)c1cc(Sc2ccc(OCC)cc2)nc2ccccc12 nan
CHEMBL1397896 30910 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 4 5.3 CCCCNC(=O)c1cc(Sc2ccc(OCC)cc2)nc2ccccc12 nan
402652 30928 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 6 3.7 O=c1c2ccccc2nc2sc(Nc3cccc(Cl)c3)nn12 nan
CHEMBL1398128 30928 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 2 1 6 3.7 O=c1c2ccccc2nc2sc(Nc3cccc(Cl)c3)nn12 nan
15988651 30929 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 4 3.8 O=C(Nc1cccc(C(F)(F)F)c1)C1CCN(S(=O)(=O)c2cccs2)CC1 nan
CHEMBL1398130 30929 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 1 4 3.8 O=C(Nc1cccc(C(F)(F)F)c1)C1CCN(S(=O)(=O)c2cccs2)CC1 nan
135455820 30940 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 5 4.6 Oc1ncnc2c1sc1nc(C(F)F)cc(-c3ccccc3)c12 nan
CHEMBL1398293 30940 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 1 5 4.6 Oc1ncnc2c1sc1nc(C(F)F)cc(-c3ccccc3)c12 nan
16019015 30951 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 6 1 5 3.5 CC(C)CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1398441 30951 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 6 1 5 3.5 CC(C)CCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16032326 30968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 6 5.9 CN1CCc2c(sc(NC(=O)CSc3ccc(F)cc3)c2-c2nc3ccccc3s2)C1 nan
CHEMBL1398567 30968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 5 1 6 5.9 CN1CCc2c(sc(NC(=O)CSc3ccc(F)cc3)c2-c2nc3ccccc3s2)C1 nan
2105201 30996 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 8 1 9 4.9 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C(C)=O)c1C nan
CHEMBL1398840 30996 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 521 8 1 9 4.9 CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C(C)=O)c1C nan
16021149 31041 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 5 5.8 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccccc3)nc3cccnc32)cc1 nan
CHEMBL1399300 31041 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 1 5 5.8 O=C(NC1CCCCC1)c1ccc(Cn2c(SCc3ccccc3)nc3cccnc32)cc1 nan
8351751 31069 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 0 8 2.1 CCOc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
CHEMBL1399515 31069 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 7 0 8 2.1 CCOc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
1386490 31083 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 0 5 4.8 COc1cccc(OCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)c1 nan
CHEMBL1399670 31083 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 0 5 4.8 COc1cccc(OCCn2c(-c3ccc(Cl)cc3)nc3ccccc3c2=O)c1 nan
16007871 31094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 1 4 5.2 O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1[S+]2[O-] nan
CHEMBL1399777 31094 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 1 4 5.2 O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1[S+]2[O-] nan
16011403 31096 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 5 6.0 O=C(NCc1ccc(F)cc1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
CHEMBL1399789 31096 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 500 8 1 5 6.0 O=C(NCc1ccc(F)cc1)c1ccc(Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1 nan
7293305 31099 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 5 3.6 COCCn1ccc2c(OCC(=O)Nc3c(C)cc(C)cc3C)cccc2c1=O nan
CHEMBL1399845 31099 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 7 1 5 3.6 COCCn1ccc2c(OCC(=O)Nc3c(C)cc(C)cc3C)cccc2c1=O nan
16030115 31235 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.4 CCc1cccc(C)c1NC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
CHEMBL1401110 31235 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 6 4.4 CCc1cccc(C)c1NC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
1163266 31249 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 1 1 5 2.2 Cc1ccc(-c2cc3ncc(C#N)c(N)n3n2)cc1 nan
CHEMBL1401234 31249 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 249 1 1 5 2.2 Cc1ccc(-c2cc3ncc(C#N)c(N)n3n2)cc1 nan
16024855 31271 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 3 1 4 5.1 Cc1cc(C)cc(NC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
CHEMBL1401368 31271 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 3 1 4 5.1 Cc1cc(C)cc(NC(=O)C2CCN(c3nc4ccccc4nc3C(F)(F)F)CC2)c1 nan
16011339 31377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 2 5 5.2 CCOC(=O)c1ccccc1NC(=O)NC(C)c1c(-n2cccc2)sc(C)c1C nan
CHEMBL1402306 31377 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 6 2 5 5.2 CCOC(=O)c1ccccc1NC(=O)NC(C)c1c(-n2cccc2)sc(C)c1C nan
16019019 31387 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 3.7 O=C(NCCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1402402 31387 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 6 1 5 3.7 O=C(NCCc1ccccc1)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16011789 31461 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 5 3.6 Cc1ccc(-n2ncc3c(=O)n(Cc4ccccc4C)cnc32)cc1C nan
CHEMBL1403021 31461 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 3 0 5 3.6 Cc1ccc(-n2ncc3c(=O)n(Cc4ccccc4C)cnc32)cc1C nan
7096324 31478 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 2 3 2.5 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)CCCC3)cc1 nan
CHEMBL1403204 31478 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 3 2 3 2.5 NS(=O)(=O)c1ccc(NC(=O)c2ccc3c(c2)CCCC3)cc1 nan
135437062 31503 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 6 3.5 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1ccc(C)c(Cl)c1 nan
CHEMBL1403479 31503 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 3 6 3.5 CCC(C)NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1ccc(C)c(Cl)c1 nan
16026084 31564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 1 7 2.1 O=C(Nc1cccc(F)c1)c1cnc2sc(N3CCCC3)nn2c1=O nan
CHEMBL1404065 31564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 3 1 7 2.1 O=C(Nc1cccc(F)c1)c1cnc2sc(N3CCCC3)nn2c1=O nan
15999042 31600 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 2.8 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sccc21)NC1CCCCC1 nan
CHEMBL1404291 31600 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 1 6 2.8 O=C(Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2sccc21)NC1CCCCC1 nan
1617675 31642 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 3 0 5 6.2 Cc1cccc(-c2nc3c4c(-c5ccccc5)c(-c5ccccc5)oc4ncn3n2)c1 nan
CHEMBL1404812 31642 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 3 0 5 6.2 Cc1cccc(-c2nc3c4c(-c5ccccc5)c(-c5ccccc5)oc4ncn3n2)c1 nan
2390567 31676 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 6 2.9 N#Cc1ccsc1NC(=O)COC(=O)c1cc(Br)ccc1O nan
CHEMBL1405202 31676 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 4 2 6 2.9 N#Cc1ccsc1NC(=O)COC(=O)c1cc(Br)ccc1O nan
15988048 31736 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 10 2 9 2.1 COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3c(C)cccc3C)c2cc1OC nan
CHEMBL1405772 31736 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 10 2 9 2.1 COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3c(C)cccc3C)c2cc1OC nan
16024912 31740 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.5 Cc1ccccc1CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1405829 31740 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 5 1 4 4.5 Cc1ccccc1CCNC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
2991576 31942 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 6 2.6 CCCCc1nc2sc3c(=O)n(N)cnc3c2c2c1CCC2 nan
CHEMBL1407541 31942 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 1 6 2.6 CCCCc1nc2sc3c(=O)n(N)cnc3c2c2c1CCC2 nan
3583749 31979 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 7 3.0 COC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)sc2c1CCN(C)C2 nan
CHEMBL1407736 31979 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 5 1 7 3.0 COC(=O)c1c(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)sc2c1CCN(C)C2 nan
3245299 31989 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 2 7 2.7 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccccc3)c2n1 nan
CHEMBL1407835 31989 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 2 7 2.7 CCOc1ccccc1-c1nc(C(N)=O)c2nc(O)n(-c3ccccc3)c2n1 nan
6485917 32038 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 9 1 8 2.6 COc1ccc(CNCCSc2nnnn2-c2ccccc2)c(OC)c1 nan
CHEMBL1408179 32038 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 9 1 8 2.6 COc1ccc(CNCCSc2nnnn2-c2ccccc2)c(OC)c1 nan
2265197 32047 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 2 2 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1)c1ccccc1F nan
CHEMBL1408256 32047 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 4 2 2 4.3 O=C(Nc1ccccc1C(=O)Nc1ccccc1)c1ccccc1F nan
15989388 32132 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 7 1 6 3.3 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(=O)N3CCc4ccccc4C3)c(=O)c3ccccc32)cc1 nan
CHEMBL1408914 32132 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 510 7 1 6 3.3 CCc1ccc(NC(=O)Cn2c(=O)n(CCC(=O)N3CCc4ccccc4C3)c(=O)c3ccccc32)cc1 nan
1082765 32221 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 8 1 6 2.9 COc1ccc(CCNC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1OC nan
CHEMBL1409638 32221 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 8 1 6 2.9 COc1ccc(CCNC(=O)COc2ccc3c(C)cc(=O)oc3c2)cc1OC nan
1913870 32248 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 2 6 3.1 O=C(/C=C\Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1 nan
CHEMBL1409860 32248 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 7 2 6 3.1 O=C(/C=C\Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1)c1ccccc1 nan
2527257 32301 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 7 2 7 1.7 COc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1OC nan
CHEMBL1410234 32301 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 7 2 7 1.7 COc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1OC nan
2201015 32311 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 3.3 Cc1ccc(-n2c3c(cc(C(=O)NCC(=O)c4ccccc4)c2=O)C(=O)CCC3)cc1 nan
CHEMBL1410319 32311 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 5 3.3 Cc1ccc(-n2c3c(cc(C(=O)NCC(=O)c4ccccc4)c2=O)C(=O)CCC3)cc1 nan
2135385 32343 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 7 4.1 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
CHEMBL1410565 32343 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 7 4.1 CCOc1ccc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3cc4c(cc32)OCO4)cc1 nan
1160042 32363 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 0 5 3.9 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 nan
CHEMBL1410783 32363 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 0 5 3.9 Cc1cc(C)c(C#N)c(SCCS(=O)(=O)Cc2ccc(Cl)cc2)n1 nan
16232595 32375 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.1 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)n1 nan
CHEMBL1410891 32375 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 1 6 3.1 Cc1cc(C)c(C#N)c(SCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)n1 nan
1963060 32389 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 0 6 2.6 COCCn1c(-c2ccccc2)nc2c(c(=O)c3ccccc3n2C)c1=O nan
CHEMBL1411041 32389 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 4 0 6 2.6 COCCn1c(-c2ccccc2)nc2c(c(=O)c3ccccc3n2C)c1=O nan
1301263 32431 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 6 4.6 COc1ccc(CC(=O)Nc2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1OC nan
CHEMBL1411349 32431 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 6 4.6 COc1ccc(CC(=O)Nc2ccc(-c3nnc(-c4ccccc4)o3)cc2)cc1OC nan
2353143 32608 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 4.4 COc1cc(SC)ccc1C(=O)Nc1ncc(Cl)cc1Cl nan
CHEMBL1412778 32608 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 4 4.4 COc1cc(SC)ccc1C(=O)Nc1ncc(Cl)cc1Cl nan
135402203 32688 14 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 1 6 3.5 COc1ccc(OCCSc2nc(O)c3ccccc3n2)cc1 nan
CHEMBL1413382 32688 14 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 6 1 6 3.5 COc1ccc(OCCSc2nc(O)c3ccccc3n2)cc1 nan
8722509 32706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 7 3.6 CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccncc3)n2C2CC2)cc1 nan
CHEMBL1413558 32706 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 7 1 7 3.6 CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccncc3)n2C2CC2)cc1 nan
3240816 32709 3 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 0 6 2.0 COC(=O)c1cn(C)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)cc2c1=O nan
CHEMBL1413578 32709 3 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 3 0 6 2.0 COC(=O)c1cn(C)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)cc2c1=O nan
3546772 32743 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 8 1 4 5.1 CC(C)OCCCNC(=O)c1cc(Sc2ccc(F)cc2)nc2ccccc12 nan
CHEMBL1413820 32743 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 8 1 4 5.1 CC(C)OCCCNC(=O)c1cc(Sc2ccc(F)cc2)nc2ccccc12 nan
2216801 32766 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.2 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCCC3)no1 nan
CHEMBL1414005 32766 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 4 1 6 3.2 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCCC3)no1 nan
16011480 32813 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1cccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3ccncc32)c1 nan
CHEMBL1414437 32813 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 1 5 6.1 Cc1cccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3ccncc32)c1 nan
3185714 32846 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 2.9 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1 nan
CHEMBL1414702 32846 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 536 9 3 8 2.9 Cc1cccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCC2CCCO2)c2ccc(N(C)C)cc2)c1 nan
16024849 32919 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 4.7 CC(NC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1)c1ccccc1 nan
CHEMBL1415340 32919 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 1 4 4.7 CC(NC(=O)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1)c1ccccc1 nan
1997619 32946 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 1 0 6 3.4 O=c1nc2sc3ccccc3n2c(=O)n1-c1ccc(Cl)c(Cl)c1 nan
CHEMBL1415577 32946 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 1 0 6 3.4 O=c1nc2sc3ccccc3n2c(=O)n1-c1ccc(Cl)c(Cl)c1 nan
601275 32973 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 7 2.7 CCc1nnc(NC(=O)CSc2nc(C)cc(C)c2C#N)s1 nan
CHEMBL1415875 32973 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 5 1 7 2.7 CCc1nnc(NC(=O)CSc2nc(C)cc(C)c2C#N)s1 nan
15988188 32998 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 2 4 2.9 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
CHEMBL1416073 32998 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 7 2 4 2.9 CCCCCn1c(=O)[nH]c2cc(C(=O)NCc3ccc(F)cc3)ccc2c1=O nan
2135587 33052 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(F)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
CHEMBL1416515 33052 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 502 7 1 7 4.2 CCOc1ccc(C(=O)c2cn(CC(=O)Nc3ccc(F)cc3)c3cc4c(cc3c2=O)OCCO4)cc1 nan
1829959 33058 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 6 4.6 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1cccs1 nan
CHEMBL1416570 33058 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 6 1 6 4.6 O=C(Nc1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccccc2)cc1)c1cccs1 nan
4044817 33075 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 4 1 6 4.1 CC(OC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3)C(=O)Nc1ccc(F)cc1Cl nan
CHEMBL1416742 33075 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 4 1 6 4.1 CC(OC(=O)c1ccc2c(=O)n3c(nc2c1)CCCCC3)C(=O)Nc1ccc(F)cc1Cl nan
16012432 33076 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 5 3.0 O=C(NCc1cccc(Cl)c1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
CHEMBL1416749 33076 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 5 3.0 O=C(NCc1cccc(Cl)c1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
16033988 33092 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 2 0 5 2.8 Cc1ccc(-n2ncc3c(N(C)C)ncnc32)cc1Cl nan
CHEMBL1416927 33092 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 287 2 0 5 2.8 Cc1ccc(-n2ncc3c(N(C)C)ncnc32)cc1Cl nan
16031129 33157 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 6 4.5 COc1ccc(OC)c(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)c1 nan
CHEMBL1417406 33157 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 2 6 4.5 COc1ccc(OC)c(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)c1 nan
16018805 33172 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 6 3.3 COc1ccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1Cl nan
CHEMBL1417571 33172 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 1 6 3.3 COc1ccc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)cc1Cl nan
1490637 33215 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 2 5 4.5 COc1ccc(NC(=O)c2ccccc2Sc2ccc(NC(C)=O)nc2)cc1 nan
CHEMBL1417935 33215 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 2 5 4.5 COc1ccc(NC(=O)c2ccccc2Sc2ccc(NC(C)=O)nc2)cc1 nan
5768421 33238 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 9 1 6 3.8 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)c(C)c2)C1c1ccncc1 nan
CHEMBL1418118 33238 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 9 1 6 3.8 COCCCN1C(=O)C(O)=C(C(=O)c2ccc(OC(C)C)c(C)c2)C1c1ccncc1 nan
16025701 33287 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 9 3.7 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4cccc(C)c4)n3)c2C)cc1OC nan
CHEMBL1418579 33287 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 9 3.7 COc1ccc(-n2nnc(-c3nsc(NC(=O)c4cccc(C)c4)n3)c2C)cc1OC nan
1248279 33310 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 7 3.9 COc1ccccc1Nc1nc(N)nc(-c2oc3ccccc3c2C)n1 nan
CHEMBL1418732 33310 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 7 3.9 COc1ccccc1Nc1nc(N)nc(-c2oc3ccccc3c2C)n1 nan
2082778 33345 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 2 3 3.6 COc1ccc(Br)c(C(=O)Nc2nc3ccccc3[nH]2)c1 nan
CHEMBL1419051 33345 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 3 2 3 3.6 COc1ccc(Br)c(C(=O)Nc2nc3ccccc3[nH]2)c1 nan
7708945 33363 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 1 4 4.3 Nc1c(-c2ccc(Cl)cc2)cnc2c(-c3ccccc3)cnn12 nan
CHEMBL1419219 33363 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 2 1 4 4.3 Nc1c(-c2ccc(Cl)cc2)cnc2c(-c3ccccc3)cnn12 nan
656027 33456 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 7 4.2 COc1ccc(CCN2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccs2)cc1OC nan
CHEMBL1420005 33456 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 7 4.2 COc1ccc(CCN2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccs2)cc1OC nan
16457257 33472 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 1 1 5 3.5 Cc1ccccc1-c1nc2c3ccccc3nc(S)n2n1 nan
CHEMBL1420123 33472 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 1 1 5 3.5 Cc1ccccc1-c1nc2c3ccccc3nc(S)n2n1 nan
5049250 33486 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 2.6 O=C(COc1cccc2cccnc12)NNC(=S)Nc1ccccc1 nan
CHEMBL1420194 33486 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 3 4 2.6 O=C(COc1cccc2cccnc12)NNC(=S)Nc1ccccc1 nan
2518728 33540 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.3 Cc1nn(Cc2ccc(F)cc2)c2sc(C(=O)Nc3nccs3)cc12 nan
CHEMBL1420654 33540 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 6 4.3 Cc1nn(Cc2ccc(F)cc2)c2sc(C(=O)Nc3nccs3)cc12 nan
1975568 33728 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 6 4.4 COc1ccc2c(c1)c1nc3ccccc3nc1n2CCCN1C(=O)c2ccccc2C1=O nan
CHEMBL1422285 33728 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 0 6 4.4 COc1ccc2c(c1)c1nc3ccccc3nc1n2CCCN1C(=O)c2ccccc2C1=O nan
2952481 33848 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 2 5 3.6 CCCC(=O)Nc1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2OC)cc1 nan
CHEMBL1423274 33848 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 7 2 5 3.6 CCCC(=O)Nc1ccc(C(=O)Nc2ccc([N+](=O)[O-])cc2OC)cc1 nan
4204373 33930 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 2 6 3.5 COc1cc2nc(S)nc(NCc3ccccc3)c2cc1OC nan
CHEMBL1423864 33930 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 5 2 6 3.5 COc1cc2nc(S)nc(NCc3ccccc3)c2cc1OC nan
3208003 33956 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cc(C)ccc2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1424112 33956 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 1 5 4.1 CCc1cc2cc(C)ccc2nc1SCC(=O)Nc1cc(C)on1 nan
4329755 34079 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 3 6.3 O=C(Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1)Nc1ccccc1 nan
CHEMBL1425135 34079 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 3 6.3 O=C(Cc1sc(-c2ccccc2Cl)nc1-c1ccccc1)Nc1ccccc1 nan
2293921 34129 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 3 5 1.5 NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 nan
CHEMBL1425666 34129 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 3 5 1.5 NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 nan
2009311 34148 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 4.6 O=C(O)CSc1ncnc2c1sc1nc(-c3ccccc3)c3c(c12)CCC3 nan
CHEMBL1425879 34148 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 6 4.6 O=C(O)CSc1ncnc2c1sc1nc(-c3ccccc3)c3c(c12)CCC3 nan
3434681 34262 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 3 5 3.9 COc1ccccc1NS(=O)(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
CHEMBL1426649 34262 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 3 5 3.9 COc1ccccc1NS(=O)(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 nan
3430748 34265 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 3 5 2.1 COc1ccc2c3c([nH]c2c1)C1CC2C(CC(O)C(OC)C2CO)CN1CC3 nan
CHEMBL1426665 34265 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 3 3 5 2.1 COc1ccc2c3c([nH]c2c1)C1CC2C(CC(O)C(OC)C2CO)CN1CC3 nan
16195448 34326 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 3 4.7 Cc1cccc(NC(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)n1 nan
CHEMBL1427245 34326 1 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 2 1 3 4.7 Cc1cccc(NC(=O)c2ccc3c(Cl)c4c(nc3c2)CCCC4)n1 nan
1206713 34456 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1cccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc12 nan
CHEMBL1428460 34456 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 5 2 5 2.9 Cc1cccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc12 nan
2085163 34487 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 3.7 CCOc1ncccc1C(=O)Nc1ccc2nc(C)sc2c1 nan
CHEMBL1428703 34487 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 3.7 CCOc1ncccc1C(=O)Nc1ccc2nc(C)sc2c1 nan
3138587 34519 3 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 5 10 -2.3 CN(C)c1ccc2nc3c(=O)[nH]c(=O)nc-3n(CC(O)C(O)C(O)CO)c2c1 nan
CHEMBL1428985 34519 3 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 6 5 10 -2.3 CN(C)c1ccc2nc3c(=O)[nH]c(=O)nc-3n(CC(O)C(O)C(O)CO)c2c1 nan
1454920 34610 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1ccccc1C)C1CC1)c1nnnn12 nan
CHEMBL1429692 34610 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1ccccc1C)C1CC1)c1nnnn12 nan
748627 34637 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 4.7 Cc1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 nan
CHEMBL1429854 34637 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 4 4.7 Cc1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 nan
1478328 34702 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.0 CCc1nc2oc3ccc(C)cc3c(=O)c2cc1C(=O)OC nan
CHEMBL1430305 34702 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 297 2 0 5 3.0 CCc1nc2oc3ccc(C)cc3c(=O)c2cc1C(=O)OC nan
2950980 34756 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 4 6 3.8 O=C(O)c1cc(S(=O)(=O)O)cc(Nc2c3ccccc3nc3ccccc23)c1O nan
CHEMBL1430778 34756 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 410 4 4 6 3.8 O=C(O)c1cc(S(=O)(=O)O)cc(Nc2c3ccccc3nc3ccccc23)c1O nan
3452486 34844 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1431571 34844 16 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 4 1 5 4.4 Cc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
2031268 34877 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1cccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)c1 nan
CHEMBL1431855 34877 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1cccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)c1 nan
16030582 35076 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 2 7 4.1 Cc1ccc2[nH]c(CSc3nnc(NC(=O)COc4ccccc4F)s3)cc(=O)c2c1 nan
CHEMBL1433463 35076 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 7 2 7 4.1 Cc1ccc2[nH]c(CSc3nnc(NC(=O)COc4ccccc4F)s3)cc(=O)c2c1 nan
16014372 35090 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccc(CSc2ncc(Cl)c(C(=O)NCc3ccccc3)n2)cc1 nan
CHEMBL1433681 35090 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccc(CSc2ncc(Cl)c(C(=O)NCc3ccccc3)n2)cc1 nan
24980276 35120 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 8 2.9 CCOC(=O)c1c(NC(=O)COC(=O)CCOc2ccccc2C)sc(C(=O)NC)c1C nan
CHEMBL1434167 35120 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 10 2 8 2.9 CCOC(=O)c1c(NC(=O)COC(=O)CCOc2ccccc2C)sc(C(=O)NC)c1C nan
17757032 35123 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 0 4 4.6 Clc1ccc2c(c1)-c1c(cnc3cc(-c4ccccc4)nn13)CO2 nan
CHEMBL1434219 35123 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 1 0 4 4.6 Clc1ccc2c(c1)-c1c(cnc3cc(-c4ccccc4)nn13)CO2 nan
16018775 35124 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 5 3.7 Cc1cc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)ccc1Br nan
CHEMBL1434221 35124 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 4 1 5 3.7 Cc1cc(NC(=O)CCn2c(=O)c3cccn3c3cccnc32)ccc1Br nan
16018825 35135 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 8 2.4 COc1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)c(OC)c1OC nan
CHEMBL1434453 35135 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 1 8 2.4 COc1ccc(CCNC(=O)CCn2c(=O)c3cccn3c3cccnc32)c(OC)c1OC nan
15989503 35142 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 3.2 Cc1cccc(NC(=O)Cn2c(=O)n(CCCS(=O)(=O)C3CCCCC3)c(=O)c3ccccc32)c1 nan
CHEMBL1434580 35142 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 8 1 7 3.2 Cc1cccc(NC(=O)Cn2c(=O)n(CCCS(=O)(=O)C3CCCCC3)c(=O)c3ccccc32)c1 nan
16034196 35143 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 5.2 CCOC(=O)c1ccc(N2CCN(c3cccc(OC)c3)CC2)c(NC(=O)Nc2ccc(OCC)cc2)c1 nan
CHEMBL1434618 35143 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 9 2 7 5.2 CCOC(=O)c1ccc(N2CCN(c3cccc(OC)c3)CC2)c(NC(=O)Nc2ccc(OCC)cc2)c1 nan
16030773 35152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 5.0 Cc1cccc(OCC(=O)Nc2cc(-c3ccccc3F)nn2-c2ccccc2)c1 nan
CHEMBL1434674 35152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 5.0 Cc1cccc(OCC(=O)Nc2cc(-c3ccccc3F)nn2-c2ccccc2)c1 nan
4153411 35180 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.6 Cc1cc(C)cc(OCC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)c1 nan
CHEMBL1435020 35180 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.6 Cc1cc(C)cc(OCC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)c1 nan
9516939 35181 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 3 1 6 3.2 COc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 nan
CHEMBL1435035 35181 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 3 1 6 3.2 COc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 nan
16016693 35196 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 5.5 CC(C)Oc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1 nan
CHEMBL1435186 35196 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 5.5 CC(C)Oc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1 nan
16026116 35213 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 9 1.7 COc1cccc(CNC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1OC nan
CHEMBL1435357 35213 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 9 1.7 COc1cccc(CNC(=O)c2cnc3sc(N4CCCC4)nn3c2=O)c1OC nan
1821611 35223 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 5 5.9 COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc3c2CCCCC3)cc1 nan
CHEMBL1435471 35223 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 7 2 5 5.9 COc1ccc(NC(=O)c2c(NC(=O)COc3ccc(Cl)cc3)sc3c2CCCCC3)cc1 nan
1251337 35231 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.2 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)cc1 nan
CHEMBL1435587 35231 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 6 3.2 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3s2)cc1 nan
16010614 35256 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(CNc2nc3ccccc3c3nc(-c4cccc(C)c4)nn23)cc1 nan
CHEMBL1435932 35256 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(CNc2nc3ccccc3c3nc(-c4cccc(C)c4)nn23)cc1 nan
16025971 35259 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 4.1 Cc1ccc(NC(=O)CSc2nc(-c3ccccc3Cl)nc3cc(=O)[nH]n23)c(C)c1 nan
CHEMBL1436000 35259 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 5 2 6 4.1 Cc1ccc(NC(=O)CSc2nc(-c3ccccc3Cl)nc3cc(=O)[nH]n23)c(C)c1 nan
16023620 35268 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 3 5 3.4 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(F)c2)N3)cc1 nan
CHEMBL1436076 35268 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 481 7 3 5 3.4 Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(CS(=O)(=O)Cc2cccc(F)c2)N3)cc1 nan
16001329 35289 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 0 7 4.9 COc1ccc(-c2nn(C)c3sc(C(=O)N4CCN(c5cccc(C)c5C)CC4)cc23)cc1OC nan
CHEMBL1436335 35289 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 5 0 7 4.9 COc1ccc(-c2nn(C)c3sc(C(=O)N4CCN(c5cccc(C)c5C)CC4)cc23)cc1OC nan
16015802 35295 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 4 6.5 Cc1ccc(SCC(=O)Nc2cccc(-c3nc4cc(Cl)ccc4o3)c2C)cc1 nan
CHEMBL1436447 35295 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 5 1 4 6.5 Cc1ccc(SCC(=O)Nc2cccc(-c3nc4cc(Cl)ccc4o3)c2C)cc1 nan
16008886 35300 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.3 COc1ccc(CNC(=O)c2cc3c(=O)oc4ccc(C)cc4c3s2)c(OC)c1 nan
CHEMBL1436510 35300 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 5 1 6 4.3 COc1ccc(CNC(=O)c2cc3c(=O)oc4ccc(C)cc4c3s2)c(OC)c1 nan
16024495 35340 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 3.3 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)cc1OC nan
CHEMBL1437062 35340 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 9 1 7 3.3 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccccc3)c(=O)c3ccc(C)nc32)cc1OC nan
16019037 35349 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 0 6 4.6 CCOC(=O)c1cnc2cc(-c3ccc(OCC)cc3)nn2c1-c1ccccc1 nan
CHEMBL1437136 35349 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 0 6 4.6 CCOC(=O)c1cnc2cc(-c3ccc(OCC)cc3)nn2c1-c1ccccc1 nan
16030417 35373 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1cccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3cc(C)ccc3n2)c1 nan
CHEMBL1437458 35373 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1cccc(OCC(=O)Nc2ccccc2OCc2cc(=O)n3cc(C)ccc3n2)c1 nan
15987619 35376 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 5.7 CCCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(Cl)c1 nan
CHEMBL1437513 35376 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 0 4 5.7 CCCN(C(=O)c1cc2c(=O)oc3ccccc3c2s1)c1cccc(Cl)c1 nan
16027516 35384 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
CHEMBL1437665 35384 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 7 1 9 3.6 COc1ccccc1C(=O)Nc1cccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)c1 nan
2986974 35388 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.5 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)COc1ccccc1C nan
CHEMBL1437693 35388 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.5 Cc1cc(-c2nc3ncccc3o2)ccc1NC(=O)COc1ccccc1C nan
16025598 35446 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 1 7 4.1 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)cc1 nan
CHEMBL1438111 35446 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 490 6 1 7 4.1 CCOc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(C)S3(=O)=O)cc1 nan
16012435 35459 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 0 4 3.7 CCc1nn(Cc2cccc(F)c2)c(=O)c2cc3cc(C)ccc3n12 nan
CHEMBL1438209 35459 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 3 0 4 3.7 CCc1nn(Cc2cccc(F)c2)c(=O)c2cc3cc(C)ccc3n12 nan
16014909 35549 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc2c(c1)cc(C(=O)NCc1ccccc1C)n2C nan
CHEMBL1439084 35549 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 2 3.7 Cc1ccc2c(c1)cc(C(=O)NCc1ccccc1C)n2C nan
992393 35571 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 5.0 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCCc1ccc(OC)c(OC)c1 nan
CHEMBL1439287 35571 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 8 1 6 5.0 CCOC(=O)c1cnc2c(C)cc(Cl)cc2c1NCCc1ccc(OC)c(OC)c1 nan
2767956 35598 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 3 4.9 CSc1cc(-c2ccc(Cl)cc2)c(C(=O)NC(C)C)s1 nan
CHEMBL1439494 35598 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 4 1 3 4.9 CSc1cc(-c2ccc(Cl)cc2)c(C(=O)NC(C)C)s1 nan
3116122 35627 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 nan
CHEMBL1439707 35627 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 5 2 7 2.1 COc1ccc(NC(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 nan
16016094 35672 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 7 5.1 COc1ccc(-c2noc(-c3ccc(NC4CCCCC4)c([N+](=O)[O-])c3)n2)cc1 nan
CHEMBL1440140 35672 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 7 5.1 COc1ccc(-c2noc(-c3ccc(NC4CCCCC4)c([N+](=O)[O-])c3)n2)cc1 nan
1630787 35718 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 3.3 CC(C)(C)NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
CHEMBL1440595 35718 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 5 2 7 3.3 CC(C)(C)NS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
16014413 35728 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccccc1CSc1ncc(Cl)c(C(=O)NCc2ccccc2)n1 nan
CHEMBL1440676 35728 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 6 1 4 4.7 Cc1ccccc1CSc1ncc(Cl)c(C(=O)NCc2ccccc2)n1 nan
15989176 35823 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 9 1 5 3.2 CCCCNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O nan
CHEMBL1441599 35823 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 9 1 5 3.2 CCCCNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O nan
16008898 35845 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 6 3.5 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1441757 35845 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 6 3.5 CCOC(=O)c1cccc(NC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
1374312 35855 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 2.6 COc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
CHEMBL1441823 35855 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 6 2 6 2.6 COc1ccc2cc(C#N)c(SCC(=O)NNC(=O)Cc3ccccc3)nc2c1 nan
979004 35859 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 0 10 2.6 CC(C)(C)c1nnc2sc(SCC(=O)c3ccc4c(c3)OCCO4)nn2c1=O nan
CHEMBL1441873 35859 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 4 0 10 2.6 CC(C)(C)c1nnc2sc(SCC(=O)c3ccc4c(c3)OCCO4)nn2c1=O nan
1860569 35883 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)cc1 nan
CHEMBL1442098 35883 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 2 0 5 4.2 Cc1ccc(-c2nc3c(c(=O)c4ccccc4n3C)c(=O)n2-c2ccccc2)cc1 nan
5302651 36073 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 5 3.7 CCc1ccc(NC(=O)CSc2nc(C)cc(COC)c2C#N)cc1 nan
CHEMBL1443840 36073 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 7 1 5 3.7 CCc1ccc(NC(=O)CSc2nc(C)cc(COC)c2C#N)cc1 nan
12006099 36111 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 13 1 7 4.1 CCCN(CCC)C(=O)Cn1c(=O)n(CCCCCC(=O)Nc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1444172 36111 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 13 1 7 4.1 CCCN(CCC)C(=O)Cn1c(=O)n(CCCCCC(=O)Nc2ccccc2)c(=O)c2sccc21 nan
16019024 36145 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.5 COCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
CHEMBL1444500 36145 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 7 1 6 2.5 COCCCNC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)cc1 nan
16034708 36148 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 3.6 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3)c2n1 nan
CHEMBL1444524 36148 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 1 5 3.6 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3)c2n1 nan
16016687 36168 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 2 5 4.8 COc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1OC nan
CHEMBL1444758 36168 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 2 5 4.8 COc1ccc(CNC(=O)Nc2ccc3c(c2)N(C)C(=O)c2ccccc2S3)cc1OC nan
3238164 36193 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 3 3.1 O=C(CCN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(F)cc1 nan
CHEMBL1444967 36193 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 3 3.1 O=C(CCN1CCN(c2ccc(F)cc2)CC1)Nc1ccc(F)cc1 nan
2296239 36194 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 8 1 6 2.7 CCn1c(SCC(=O)NCCOc2ccccc2)nc2ccccc2c1=O nan
CHEMBL1444971 36194 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 8 1 6 2.7 CCn1c(SCC(=O)NCCOc2ccccc2)nc2ccccc2c1=O nan
657584 36205 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 5 3.9 CC(C)Cc1nc(N2CCN(C(=O)Cc3ccccc3)CC2)c(C#N)c2c1COC(C)(C)C2 nan
CHEMBL1445051 36205 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 5 3.9 CC(C)Cc1nc(N2CCN(C(=O)Cc3ccccc3)CC2)c(C#N)c2c1COC(C)(C)C2 nan
15988979 36258 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 7 3.2 O=C(CCn1c(=O)c2sccc2n(CC(=O)Nc2ccccc2)c1=O)NCc1ccccc1Cl nan
CHEMBL1445545 36258 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 8 2 7 3.2 O=C(CCn1c(=O)c2sccc2n(CC(=O)Nc2ccccc2)c1=O)NCc1ccccc1Cl nan
16023569 36283 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.1 CC(=O)c1ccc(N2CCN(C(=O)CCn3cnc4onc(-c5ccc(F)cc5)c4c3=O)CC2)cc1 nan
CHEMBL1445781 36283 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 489 6 0 8 3.1 CC(=O)c1ccc(N2CCN(C(=O)CCn3cnc4onc(-c5ccc(F)cc5)c4c3=O)CC2)cc1 nan
7157939 36308 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 2 3 3.1 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cc(Cl)ccc1Cl nan
CHEMBL1446030 36308 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 2 2 3 3.1 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1cc(Cl)ccc1Cl nan
1480468 36370 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 5 3.9 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccccc2)c1C#N nan
CHEMBL1446611 36370 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 4 1 5 3.9 CC(C)Nc1nc(-c2ccncc2)nc(-c2ccccc2)c1C#N nan
2195706 36397 7 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 8 2.8 CCOC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1446861 36397 7 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 1 8 2.8 CCOC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
16010637 36435 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 4.7 CCN(Cc1ccccc1)C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 nan
CHEMBL1447092 36435 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 4.7 CCN(Cc1ccccc1)C(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 nan
2130696 36533 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.9 N#C/C(C(=O)NCc1ccco1)=C1/SC=C(c2ccccc2)N1c1ccccc1 nan
CHEMBL1447960 36533 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.9 N#C/C(C(=O)NCc1ccco1)=C1/SC=C(c2ccccc2)N1c1ccccc1 nan
4583349 36580 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 5 2.2 Cc1ccc(NC(=O)CCn2c(=O)[nH]c3ccsc3c2=O)cc1F nan
CHEMBL1448388 36580 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 2 5 2.2 Cc1ccc(NC(=O)CCn2c(=O)[nH]c3ccsc3c2=O)cc1F nan
5396132 36662 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 0 5 3.7 COc1cc(/C=C2/C(=O)ON=C2C)ccc1OCc1ccccc1F nan
CHEMBL1448972 36662 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 5 0 5 3.7 COc1cc(/C=C2/C(=O)ON=C2C)ccc1OCc1ccccc1F nan
1201887 36688 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 0 3 4.0 Cc1cccc(CSc2nc3c(cc2C#N)CCC3)c1 nan
CHEMBL1449126 36688 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 280 3 0 3 4.0 Cc1cccc(CSc2nc3c(cc2C#N)CCC3)c1 nan
649163 36692 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 5 3.0 CCN(CC)S(=O)(=O)c1ccc(Cl)c(C(=O)Oc2cccnc2)c1 nan
CHEMBL1449162 36692 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 0 5 3.0 CCN(CC)S(=O)(=O)c1ccc(Cl)c(C(=O)Oc2cccnc2)c1 nan
16019152 36749 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 7 4.0 Cc1ccccc1Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
CHEMBL1449607 36749 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 0 7 4.0 Cc1ccccc1Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2oc3ccccc3c21 nan
16017274 36768 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.6 CCN(CC)c1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
CHEMBL1449789 36768 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 6 1 6 2.6 CCN(CC)c1ccc(NC(=O)Cn2nc(C)n3cccc3c2=O)c(C)c1 nan
15996185 36776 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 2 4 4.7 CCC(C)NC(=O)CCC(=O)Nc1ccc2nc(N3CC(C)CC(C)C3)cc(C)c2c1 nan
CHEMBL1449862 36776 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 2 4 4.7 CCC(C)NC(=O)CCC(=O)Nc1ccc2nc(N3CC(C)CC(C)C3)cc(C)c2c1 nan
15989912 36780 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 7 5.4 Cc1cc(C)n(-c2nc3ccccc3nc2Nc2ccc(Cl)c(C(=O)OC(C)C)c2)n1 nan
CHEMBL1449881 36780 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 5 1 7 5.4 Cc1cc(C)n(-c2nc3ccccc3nc2Nc2ccc(Cl)c(C(=O)OC(C)C)c2)n1 nan
16020571 36941 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 4.2 CCn1cc(S(=O)(=O)c2cc(C)cc(C)c2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
CHEMBL1451264 36941 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 4 0 5 4.2 CCn1cc(S(=O)(=O)c2cc(C)cc(C)c2)c(=O)c2cc(F)c(N3CCCC3)cc21 nan
5058847 37084 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
CHEMBL1452293 37084 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 1 6 3.0 COc1cc(NC(=O)Cn2c(C)cc3ccccc3c2=O)cc(OC)c1OC nan
15988482 37214 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.4 Cc1ccc(C(=O)c2cn(Cc3ccc(F)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1453340 37214 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 4 0 4 4.4 Cc1ccc(C(=O)c2cn(Cc3ccc(F)cc3)c3nc(C)ccc3c2=O)cc1 nan
16019909 37222 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 0 8 3.8 COc1cc(-c2noc(-c3cc4cccc(C)c4oc3=O)n2)cc(OC)c1OC nan
CHEMBL1453424 37222 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 5 0 8 3.8 COc1cc(-c2noc(-c3cc4cccc(C)c4oc3=O)n2)cc(OC)c1OC nan
16024781 37263 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 4 1.9 O=C1C(=O)N(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)CCN1Cc1ccccc1 nan
CHEMBL1453815 37263 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 0 4 1.9 O=C1C(=O)N(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)CCN1Cc1ccccc1 nan
16024608 37273 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 1 7 3.5 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1OC nan
CHEMBL1453881 37273 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 503 9 1 7 3.5 COc1ccc(CCNC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc1OC nan
3940076 37286 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 1 5 3.3 Cc1ccc(CNc2nc3nc(C)c(Cl)c(C)n3n2)cc1 nan
CHEMBL1453947 37286 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 3 1 5 3.3 Cc1ccc(CNc2nc3nc(C)c(Cl)c(C)n3n2)cc1 nan
1604929 37291 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 5 4.6 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)c1 nan
CHEMBL1453974 37291 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 0 5 4.6 CCCCn1cc[n+](-c2nc3ccccc3nc2[N-]S(=O)(=O)c2ccc(Cl)cc2)c1 nan
707946 37317 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 3.0 O=C(Nc1nc2nccc(-c3ccccc3)n2n1)c1ccccc1 nan
CHEMBL1454141 37317 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 5 3.0 O=C(Nc1nc2nccc(-c3ccccc3)n2n1)c1ccccc1 nan
16010581 37333 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c1 nan
CHEMBL1454246 37333 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1cc(C)cc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c1 nan
15988208 37401 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 9 1.7 COC(=O)c1cccnc1-n1c(=O)c2cccnc2n(CC(=O)Nc2cccc(C)c2)c1=O nan
CHEMBL1454833 37401 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 1 9 1.7 COC(=O)c1cccnc1-n1c(=O)c2cccnc2n(CC(=O)Nc2cccc(C)c2)c1=O nan
5123668 37458 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 10 1 7 5.2 CCc1ccc(NC(=O)CSc2nc3c(sc4ccccc43)c(=O)n2CCN(CC)CC)cc1 nan
CHEMBL1455415 37458 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 10 1 7 5.2 CCc1ccc(NC(=O)CSc2nc3c(sc4ccccc43)c(=O)n2CCN(CC)CC)cc1 nan
135421575 37513 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 2 4 3.3 CCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
CHEMBL1455904 37513 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 2 4 3.3 CCn1c(=O)c(-c2nc3ccccc3[nH]2)c(O)c2ccccc21 nan
914701 37540 8 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 4 4.3 CCc1nc2sc3c(Cl)ncnc3c2c2c1CCCC2 nan
CHEMBL1456130 37540 8 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 4 4.3 CCc1nc2sc3c(Cl)ncnc3c2c2c1CCCC2 nan
2023595 37664 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
CHEMBL1457309 37664 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 5 1 6 4.1 COc1cccc(NC(=O)CSc2ncnc3c2oc2ccccc23)c1 nan
16024557 37700 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(Cl)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
CHEMBL1457615 37700 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 5 1 5 4.0 Cc1ccc2c(=O)c(C(=O)c3ccc(Cl)cc3)cn(CC(=O)NC3CCCCC3)c2n1 nan
20920344 37723 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 4.4 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5cccs5)CC4)nnc(C)c3c2C)cc1 nan
CHEMBL1457782 37723 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 1 7 4.4 Cc1ccc(-n2nc3c(N4CCC(C(=O)NCCc5cccs5)CC4)nnc(C)c3c2C)cc1 nan
3245484 37853 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 2 7 1.9 COc1cc2[nH]c(=O)n(CCC(=O)NC3CCN(Cc4ccccc4)CC3)c(=O)c2cc1OC nan
CHEMBL1458892 37853 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 8 2 7 1.9 COc1cc2[nH]c(=O)n(CCC(=O)NC3CCN(Cc4ccccc4)CC3)c(=O)c2cc1OC nan
2467173 37875 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 9 1 11 1.4 C=CCn1c(SCC(=O)c2c(N)n(CCC)c(=O)n(C)c2=O)nnc1-c1ccncc1 nan
CHEMBL1459057 37875 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 9 1 11 1.4 C=CCn1c(SCC(=O)c2c(N)n(CCC)c(=O)n(C)c2=O)nnc1-c1ccncc1 nan
3185309 37902 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 10 3 9 3.7 COc1ccc(OC)c(C(C(=O)NC2CCCCC2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2OC)c1 nan
CHEMBL1459257 37902 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 567 10 3 9 3.7 COc1ccc(OC)c(C(C(=O)NC2CCCCC2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2OC)c1 nan
2910207 37919 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 7 1 6 3.9 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccco1 nan
CHEMBL1459409 37919 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 7 1 6 3.9 O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1cccc(Br)c1)c1ccco1 nan
2138506 38052 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 2 6 3.0 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(C(=O)OCC)CC1 nan
CHEMBL1460540 38052 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 5 2 6 3.0 CCOC(=O)c1[nH]c2ccc(OC)cc2c1N=C(S)N1CCN(C(=O)OCC)CC1 nan
1995746 38065 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 3 8 0.9 NC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccccn3)n2N)cc1 nan
CHEMBL1460633 38065 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 6 3 8 0.9 NC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccccn3)n2N)cc1 nan
1511731 38093 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 2.9 COc1ccc(C(=O)Nc2nc(C)c3cc4c(cc3n2)OCO4)cc1 nan
CHEMBL1460863 38093 18 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 3 1 6 2.9 COc1ccc(C(=O)Nc2nc(C)c3cc4c(cc3n2)OCO4)cc1 nan
4340474 38144 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 6 2 6 2.1 CCCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3 nan
CHEMBL1461327 38144 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 6 2 6 2.1 CCCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3 nan
2331607 38174 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 1 5 2.7 O=C(Nc1ccccn1)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O nan
CHEMBL1461642 38174 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 2 1 5 2.7 O=C(Nc1ccccn1)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O nan
4594455 38234 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 7 3.9 CSc1nc(N2CCN(c3ccccc3)CC2)cc(N2CCN(c3ccccc3)CC2)n1 nan
CHEMBL1462148 38234 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 5 0 7 3.9 CSc1nc(N2CCN(c3ccccc3)CC2)cc(N2CCN(c3ccccc3)CC2)n1 nan
661296 38265 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 2 1 3.2 CCc1c(C(=O)O)[nH]c2ccc(Br)cc12 nan
CHEMBL1462380 38265 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 267 2 2 1 3.2 CCc1c(C(=O)O)[nH]c2ccc(Br)cc12 nan
3183779 38296 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.7 Oc1nc2cc3c(cc2cc1C(c1nnnn1Cc1ccccc1)N1CCCCCC1)OCCO3 nan
CHEMBL1462671 38296 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 5 1 9 3.7 Oc1nc2cc3c(cc2cc1C(c1nnnn1Cc1ccccc1)N1CCCCCC1)OCCO3 nan
5418960 38315 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 4 3.3 O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCCC3 nan
CHEMBL1462820 38315 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 309 1 1 4 3.3 O=c1c2cc3c(nc2[nH]c(=S)n1-c1ccccc1)CCCC3 nan
2766000 38347 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 1 8 3.9 COCCCn1c(SCc2ccc(OC)cc2)nc2cc(OC)c(OC)cc2c1=N nan
CHEMBL1463048 38347 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 10 1 8 3.9 COCCCn1c(SCc2ccc(OC)cc2)nc2cc(OC)c(OC)cc2c1=N nan
16188024 38370 2 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1ccc2nc(O)c3cc(C(=O)N(C)c4ccccc4C)sc3c2c1 nan
CHEMBL1463271 38370 2 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1ccc2nc(O)c3cc(C(=O)N(C)c4ccccc4C)sc3c2c1 nan
4429285 38384 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 7 3.7 COC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(C)c2)cc1 nan
CHEMBL1463413 38384 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 7 3.7 COC(=O)c1ccc(Nc2ncnc3c2cnn3-c2cccc(C)c2)cc1 nan
1738267 38389 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 8 1 4 5.2 O=C(CCC(=O)OCC(=O)c1ccc(-c2ccccc2)cc1)Nc1cccc(Cl)c1 nan
CHEMBL1463488 38389 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 8 1 4 5.2 O=C(CCC(=O)OCC(=O)c1ccc(-c2ccccc2)cc1)Nc1cccc(Cl)c1 nan
3761375 38513 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 0 4 4.3 CSc1nc(C)c2c(n1)N(c1ccc(C(C)C)cc1)CC2 nan
CHEMBL1464437 38513 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 0 4 4.3 CSc1nc(C)c2c(n1)N(c1ccc(C(C)C)cc1)CC2 nan
2044631 38568 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 2 4 4.3 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(C)c1 nan
CHEMBL1464810 38568 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 2 4 4.3 Cc1cc(C)c(NC(=O)CSc2nc3cc(Br)c[nH]c-3n2)c(C)c1 nan
2372173 38614 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccccc2F)nc1-c1ccccc1 nan
CHEMBL1465138 38614 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 4 4.4 CC(=O)c1sc(NC(=O)c2ccccc2F)nc1-c1ccccc1 nan
2988623 38836 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 0 6 3.2 CCOc1ccc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)cc1 nan
CHEMBL1466802 38836 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 0 6 3.2 CCOc1ccc(C(=O)N2CCN(c3cnn(-c4ccccc4)c(=O)c3Cl)CC2)cc1 nan
2428874 38856 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 1.9 O=C(Nc1cccc2c1C(=O)NC2=O)c1cccnc1Cl nan
CHEMBL1466996 38856 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 1.9 O=C(Nc1cccc2c1C(=O)NC2=O)c1cccnc1Cl nan
3574259 38876 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
CHEMBL1467198 38876 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1cccc(Cl)c1 nan
16007702 38908 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 5 2.6 CCn1cc(C(=O)NCCc2ccc(C)cc2)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21 nan
CHEMBL1467433 38908 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 7 1 5 2.6 CCn1cc(C(=O)NCCc2ccc(C)cc2)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21 nan
663318 38921 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 0 6 4.3 CC1CCN(c2nc3ccccc3nc2C(C#N)C(=O)OC2CCCCC2)CC1 nan
CHEMBL1467520 38921 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 4 0 6 4.3 CC1CCN(c2nc3ccccc3nc2C(C#N)C(=O)OC2CCCCC2)CC1 nan
2820576 39020 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.4 Cc1csc2sc(-c3ccnc(SCC(=O)NCc4ccccc4)n3)c(C)c12 nan
CHEMBL1468435 39020 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 6 1 6 5.4 Cc1csc2sc(-c3ccnc(SCC(=O)NCc4ccccc4)n3)c(C)c12 nan
970728 39038 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 2 2 5.0 Cc1cc(C)nc(NC(S)=Nc2cccc(Cl)c2Cl)c1 nan
CHEMBL1468575 39038 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 325 2 2 2 5.0 Cc1cc(C)nc(NC(S)=Nc2cccc(Cl)c2Cl)c1 nan
4294342 39041 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 2 2 3.6 Cc1cc2cc(CNC(=O)NC3CCCCC3)ccc2n1C nan
CHEMBL1468608 39041 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 3 2 2 3.6 Cc1cc2cc(CNC(=O)NC3CCCCC3)ccc2n1C nan
648454 39048 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 4 3.4 Cc1cc(C)nc(N2CCC(C(=O)Nc3ccc4c(c3)CCC4)CC2)n1 nan
CHEMBL1468653 39048 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 4 3.4 Cc1cc(C)nc(N2CCC(C(=O)Nc3ccc4c(c3)CCC4)CC2)n1 nan
7202588 39132 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 7 2.9 COC(=O)c1ccc2nc(NC(=O)CCS(=O)(=O)c3ccccc3)sc2c1 nan
CHEMBL1469363 39132 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 6 1 7 2.9 COC(=O)c1ccc2nc(NC(=O)CCS(=O)(=O)c3ccccc3)sc2c1 nan
1073207 39272 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 0 9 2.4 COc1ccc(-n2nnnc2SCC(=O)c2ccc3c(c2)OCCO3)cc1 nan
CHEMBL1470594 39272 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 6 0 9 2.4 COc1ccc(-n2nnnc2SCC(=O)c2ccc3c(c2)OCCO3)cc1 nan
3615142 39273 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.0 Cc1c(C(=O)Nc2cccnc2Cl)oc2ccccc12 nan
CHEMBL1470599 39273 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 286 2 1 3 4.0 Cc1c(C(=O)Nc2cccnc2Cl)oc2ccccc12 nan
16009952 39510 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 7 0.9 Cc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1F nan
CHEMBL1472658 39510 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 5 1 7 0.9 Cc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1F nan
1892783 39518 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 3 1 5 4.8 Cc1ccc(-c2nnc3c4ccccc4c(C)nn23)cc1NC(=O)c1ccccc1 nan
CHEMBL1472759 39518 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 3 1 5 4.8 Cc1ccc(-c2nnc3c4ccccc4c(C)nn23)cc1NC(=O)c1ccccc1 nan
16008277 39522 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 1 5 5.8 Cc1cc(N2CCC(C(=O)Nc3ccc(F)cc3F)CC2)n2nc(C)c(-c3ccc(Cl)cc3)c2n1 nan
CHEMBL1472790 39522 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 4 1 5 5.8 Cc1cc(N2CCC(C(=O)Nc3ccc(F)cc3F)CC2)n2nc(C)c(-c3ccc(Cl)cc3)c2n1 nan
16015830 39525 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 4 5.1 O=C(COc1ccccc1F)Nc1ccc(-c2nc3ccccc3s2)cc1 nan
CHEMBL1472798 39525 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 1 4 5.1 O=C(COc1ccccc1F)Nc1ccc(-c2nc3ccccc3s2)cc1 nan
16030736 39535 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 3 5.3 CC(C)(C)C(=O)Nc1cc(-c2cccc(Br)c2)nn1-c1ccccc1 nan
CHEMBL1472994 39535 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 3 1 3 5.3 CC(C)(C)C(=O)Nc1cc(-c2cccc(Br)c2)nn1-c1ccccc1 nan
16015144 39538 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 1 5 4.6 O=C(/C=C/c1ccc(Cl)cc1)Nc1nc(-c2cccs2)ns1 nan
CHEMBL1472998 39538 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 4 1 5 4.6 O=C(/C=C/c1ccc(Cl)cc1)Nc1nc(-c2cccs2)ns1 nan
16010790 39566 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 7 2.7 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
CHEMBL1473410 39566 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 6 1 7 2.7 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3ccc(C)c(F)c3)c2=O)cc1 nan
16009809 39568 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 2 5 5.9 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1 nan
CHEMBL1473436 39568 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 6 2 5 5.9 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C23CC4CC(CC(C4)C2)C3)c(OC)c1 nan
16009067 39573 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 1 3 5.5 Cc1ccc2nc(Cl)c3cc(C(=O)NC4CCCCC4)sc3c2c1 nan
CHEMBL1473455 39573 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 2 1 3 5.5 Cc1ccc2nc(Cl)c3cc(C(=O)NC4CCCCC4)sc3c2c1 nan
864758 39580 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 6 2.1 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
CHEMBL1473580 39580 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 4 1 6 2.1 CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 nan
16010866 39581 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 7 2.9 COc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1Cl nan
CHEMBL1473610 39581 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 1 7 2.9 COc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1Cl nan
16008902 39583 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 4 3.3 Cc1cccc(CCNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
CHEMBL1473624 39583 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 4 1 4 3.3 Cc1cccc(CCNC(=O)c2cc3c(=O)n(C)c4ccccc4c3n2C)c1 nan
4425770 39589 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 4.4 Cc1cccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)o2)c1 nan
CHEMBL1473697 39589 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 4.4 Cc1cccc(-c2nnc(SCC(=O)Nc3ccc(C)c(C)c3)o2)c1 nan
16025407 39594 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 6 1 6 5.2 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2cccc(F)c2)S3(=O)=O)cc1F nan
CHEMBL1473728 39594 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 538 6 1 6 5.2 Cc1ccc(NC(=O)CSc2ncc3c(n2)-c2ccccc2N(Cc2cccc(F)c2)S3(=O)=O)cc1F nan
15989780 39640 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.9 Clc1ccc(CCNc2nc3cc(Cl)c(Cl)cc3n3cnnc23)cc1 nan
CHEMBL1474477 39640 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 4 1 5 4.9 Clc1ccc(CCNc2nc3cc(Cl)c(Cl)cc3n3cnnc23)cc1 nan
16034729 39652 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 7 5.0 COc1ccc(-c2cn3nc(N4CCC(C(=O)Nc5cccc(Cl)c5)CC4)sc3n2)cc1 nan
CHEMBL1474594 39652 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 5 1 7 5.0 COc1ccc(-c2cn3nc(N4CCC(C(=O)Nc5cccc(Cl)c5)CC4)sc3n2)cc1 nan
16012452 39664 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 5 2.4 O=C(NCc1ccccc1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
CHEMBL1474806 39664 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 3 2 5 2.4 O=C(NCc1ccccc1)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 nan
16020997 39666 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.9 Cc1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1F nan
CHEMBL1474813 39666 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 6 1 5 4.9 Cc1ccc(NC(=O)Cn2c(SCc3ccc(F)cc3)nc3cccnc32)cc1F nan
16012520 39694 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 5 4.9 CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccccc3)c2C)cc1 nan
CHEMBL1475217 39694 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 2 5 4.9 CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccccc3)c2C)cc1 nan
16008390 39699 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 4 4.2 CCc1ccc(CNC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1 nan
CHEMBL1475336 39699 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 6 1 4 4.2 CCc1ccc(CNC(=O)CSc2cc(=O)n(C)c3ccc(Cl)cc23)cc1 nan
3225367 39703 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 3 5.8 Cc1cccc(C)c1NC(=O)c1cc2sccc2n1Cc1ccc(F)cc1 nan
CHEMBL1475367 39703 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 3 5.8 Cc1cccc(C)c1NC(=O)c1cc2sccc2n1Cc1ccc(F)cc1 nan
1983981 39711 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 5.2 Cc1ccc(-c2nn3c(-c4ccc(C)cc4)nnc3c3ccccc23)cc1 nan
CHEMBL1475431 39711 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 2 0 4 5.2 Cc1ccc(-c2nn3c(-c4ccc(C)cc4)nnc3c3ccccc23)cc1 nan
16030137 39725 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 7 1 7 3.6 CCOc1ccccc1CNC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
CHEMBL1475622 39725 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 465 7 1 7 3.6 CCOc1ccccc1CNC(=O)Cn1nc(C)c2nn(-c3ccc(Cl)cc3)c(C)c2c1=O nan
16016540 39727 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 2 3.7 Cc1cc(=O)c2cc(C(=O)Nc3cccc(C)c3C)ccc2[nH]1 nan
CHEMBL1475643 39727 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 306 2 2 2 3.7 Cc1cc(=O)c2cc(C(=O)Nc3cccc(C)c3C)ccc2[nH]1 nan
16026533 39735 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 7 4.0 COc1ccc(OC)c(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
CHEMBL1475722 39735 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 446 6 1 7 4.0 COc1ccc(OC)c(NC(=O)C(C)n2c(=O)cc(C)c3c(C)nn(-c4ccccc4)c32)c1 nan
16030897 39739 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 1 6 4.8 COc1ccc(-c2cn3nc(SCC(=O)Nc4cccc(C)c4C)ccc3n2)cc1 nan
CHEMBL1475786 39739 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 1 6 4.8 COc1ccc(-c2cn3nc(SCC(=O)Nc4cccc(C)c4C)ccc3n2)cc1 nan
16012637 39760 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 0 10 3.3 Cc1ccc2nc3c(cc(C#N)c(=O)n3-c3nnc(SCc4ccccc4)s3)c(=O)n2c1 nan
CHEMBL1476168 39760 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 4 0 10 3.3 Cc1ccc2nc3c(cc(C#N)c(=O)n3-c3nnc(SCc4ccccc4)s3)c(=O)n2c1 nan
16009819 39770 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 8 4.3 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1Cl nan
CHEMBL1476323 39770 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 495 6 1 8 4.3 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)cc1Cl nan
16009801 39776 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)c(OC)c1 nan
CHEMBL1476410 39776 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 491 7 1 9 3.7 COc1ccc(NC(=O)Cn2c(=O)n(Cc3ccco3)c(=O)c3sc4ccccc4c32)c(OC)c1 nan
15987507 39781 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 6.1 Cc1cc(C)c2oc(-c3ccc(Cl)c(NC(=O)c4cccs4)c3)nc2c1 nan
CHEMBL1476493 39781 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 6.1 Cc1cc(C)c2oc(-c3ccc(Cl)c(NC(=O)c4cccs4)c3)nc2c1 nan
16030393 39789 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 4 5.2 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCc3ccccc32)cc1 nan
CHEMBL1476572 39789 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 425 5 0 4 5.2 Cc1ccc(Cc2nc3ccccc3nc2SCC(=O)N2CCc3ccccc32)cc1 nan
16010862 39797 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1C nan
CHEMBL1476637 39797 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 1 6 2.9 Cc1ccc(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)cc1C nan
4154280 39810 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 5.9 CCc1ccccc1NC(=O)C(CC)Sc1ncnc2c1sc1ccccc12 nan
CHEMBL1476806 39810 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 6 1 5 5.9 CCc1ccccc1NC(=O)C(CC)Sc1ncnc2c1sc1ccccc12 nan
7184887 39824 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 8 3.4 CC1CCN(c2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)CC1 nan
CHEMBL1476979 39824 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 8 3.4 CC1CCN(c2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)CC1 nan
666072 39926 8 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 6 4.6 CSc1ccc(-c2c(C#N)c(N)nc3c2c(C)nn3-c2ccccc2)cc1 nan
CHEMBL1477886 39926 8 None -5 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 3 1 6 4.6 CSc1ccc(-c2c(C#N)c(N)nc3c2c(C)nn3-c2ccccc2)cc1 nan
2810062 39941 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 1 6 2.9 Cc1csc2c(=O)sc(NC(=O)c3ccco3)nc12 nan
CHEMBL1478110 39941 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 2 1 6 2.9 Cc1csc2c(=O)sc(NC(=O)c3ccco3)nc12 nan
16014364 39973 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 4.8 Cc1ccc(CNC(=O)c2nc(SCc3ccc(F)cc3)ncc2Cl)cc1 nan
CHEMBL1478416 39973 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 6 1 4 4.8 Cc1ccc(CNC(=O)c2nc(SCc3ccc(F)cc3)ncc2Cl)cc1 nan
947086 39996 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 0 4 4.1 COc1ccc(-c2c(C#N)c(C)nc3c2C(=O)c2ccccc2-3)cc1 nan
CHEMBL1478573 39996 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 0 4 4.1 COc1ccc(-c2c(C#N)c(C)nc3c2C(=O)c2ccccc2-3)cc1 nan
15990421 40007 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 1 4 5.9 Cc1cc(Br)ccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1478684 40007 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 3 1 4 5.9 Cc1cc(Br)ccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
2150494 40019 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 7 3.8 COCCn1c(SCC(=O)Nc2ccc(C)cc2)nc2c(oc3ccccc32)c1=O nan
CHEMBL1478802 40019 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 7 1 7 3.8 COCCn1c(SCC(=O)Nc2ccc(C)cc2)nc2c(oc3ccccc32)c1=O nan
9267240 40027 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 O=C(Nc1ccc(Cl)cc1F)c1ccc(-n2cncn2)cc1 nan
CHEMBL1478883 40027 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 3.3 O=C(Nc1ccc(Cl)cc1F)c1ccc(-n2cncn2)cc1 nan
16015604 40067 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 6.3 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(C)cc3)on2)cc1 nan
CHEMBL1479260 40067 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 466 7 1 6 6.3 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccc(C)cc3)on2)cc1 nan
4050786 40139 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 2.8 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(NC(C)=O)ccc21 nan
CHEMBL1479784 40139 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 7 2.8 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(NC(C)=O)ccc21 nan
16009694 40141 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 8 4.6 COc1ccc(-c2nnn3c2nc(NCCc2ccc(OC)c(OC)c2)c2ccccc23)cc1 nan
CHEMBL1479788 40141 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 8 1 8 4.6 COc1ccc(-c2nnn3c2nc(NCCc2ccc(OC)c(OC)c2)c2ccccc23)cc1 nan
2140519 40302 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 3 6 1.2 COC(=O)CCC(=O)NC(=S)Nc1sc(C)c(C)c1C(N)=O nan
CHEMBL1481122 40302 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 3 6 1.2 COC(=O)CCC(=O)NC(=S)Nc1sc(C)c(C)c1C(N)=O nan
16189596 40315 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 4 4.5 CCN1CCCc2cc(CN(CCN3CCOCC3)C(S)=Nc3ccccc3C)ccc21 nan
CHEMBL1481195 40315 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 4 4.5 CCN1CCCc2cc(CN(CCN3CCOCC3)C(S)=Nc3ccccc3C)ccc21 nan
6324455 40399 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 4 3.1 CCN(CC)S(=O)(=O)c1ccc2nc(O)c3ccccc3c2c1 nan
CHEMBL1482015 40399 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 4 1 4 3.1 CCN(CC)S(=O)(=O)c1ccc2nc(O)c3ccccc3c2c1 nan
4898982 40424 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 5 2.9 COc1ccc2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)[nH]c2c1 nan
CHEMBL1482223 40424 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 4 1 5 2.9 COc1ccc2cc(C(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)[nH]c2c1 nan
16194617 40434 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 6 4.4 CCOc1ncccc1C(=O)Nc1cccc(-c2nc3cccnc3s2)c1 nan
CHEMBL1482332 40434 9 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 1 6 4.4 CCOc1ncccc1C(=O)Nc1cccc(-c2nc3cccnc3s2)c1 nan
7598416 40538 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 2.6 Cc1cccc(Cn2cccc(C(=O)Nc3nnc(C)s3)c2=O)c1 nan
CHEMBL1483270 40538 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 340 4 1 6 2.6 Cc1cccc(Cn2cccc(C(=O)Nc3nnc(C)s3)c2=O)c1 nan
16033878 40550 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 6 4.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccccc3nc2s1 nan
CHEMBL1483384 40550 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 2 1 6 4.0 Cc1c(Cl)cccc1Nc1nn2c(=O)c3ccccc3nc2s1 nan
5033969 40594 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 4 3.0 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)c(S(=O)(=O)N(C)C)c2)c1C nan
CHEMBL1483695 40594 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 5 2 4 3.0 CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(Cl)c(S(=O)(=O)N(C)C)c2)c1C nan
2346667 40604 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 6 0 5 2.8 COc1ccc(C(=O)COC(=O)c2ccc(N(C)C)cc2)cc1 nan
CHEMBL1483762 40604 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 6 0 5 2.8 COc1ccc(C(=O)COC(=O)c2ccc(N(C)C)cc2)cc1 nan
4199549 40625 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 9 0 6 4.9 CCOc1ccccc1C(=O)N1CCc2cc(OC)c(OC)cc2C1COc1ccc(OC)cc1 nan
CHEMBL1483991 40625 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 9 0 6 4.9 CCOc1ccccc1C(=O)N1CCc2cc(OC)c(OC)cc2C1COc1ccc(OC)cc1 nan
135399202 40690 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 5 3.1 NC1=C(c2nc3ccccc3s2)C(=O)CN1C1CCCCC1 nan
CHEMBL1484439 40690 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 5 3.1 NC1=C(c2nc3ccccc3s2)C(=O)CN1C1CCCCC1 nan
2377756 40726 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 6 3.4 O=C(O)c1cccnc1Sc1ncnc2sc3c(c12)CCC3 nan
CHEMBL1484807 40726 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 3 1 6 3.4 O=C(O)c1cccnc1Sc1ncnc2sc3c(c12)CCC3 nan
135410529 40765 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 4.7 CCS(=O)(=O)c1cccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c1 nan
CHEMBL1485170 40765 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 5 2 6 4.7 CCS(=O)(=O)c1cccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)c(O)c2)c1 nan
135521955 40804 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1cc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)ccc1Cl nan
CHEMBL1485562 40804 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 7 2 7 4.7 Cc1cc(-n2c(SCC(=O)NCCC3=CCCCC3)nc3nnc(C)c-3c2N)ccc1Cl nan
15989053 40816 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 1 8 4.0 Cc1cc(C)c(Cn2c(=O)n(CCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1485622 40816 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 8 1 8 4.0 Cc1cc(C)c(Cn2c(=O)n(CCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
4277738 40828 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 3 4.8 Sc1nc(-c2ccc(Br)cc2)cn1CCc1ccccc1 nan
CHEMBL1485734 40828 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 4 1 3 4.8 Sc1nc(-c2ccc(Br)cc2)cn1CCc1ccccc1 nan
16012072 40864 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 11 1 6 3.8 CCCCN(C)CCCNC(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O nan
CHEMBL1486036 40864 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 477 11 1 6 3.8 CCCCN(C)CCCNC(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O nan
1273744 40894 11 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 7 3.8 Cc1cc(C)c(C#N)c(SCC(=O)Nc2nnc(-c3ccccc3)s2)n1 nan
CHEMBL1486391 40894 11 None -6 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 5 1 7 3.8 Cc1cc(C)c(C#N)c(SCC(=O)Nc2nnc(-c3ccccc3)s2)n1 nan
16021806 40917 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 4 5.1 CSc1ncc(C(=O)Nc2ccccc2C(F)(F)F)c(-c2ccccc2)n1 nan
CHEMBL1486543 40917 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 4 1 4 5.1 CSc1ncc(C(=O)Nc2ccccc2C(F)(F)F)c(-c2ccccc2)n1 nan
5339079 40946 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 4 4.4 Cc1nc(-c2ccccc2)nc2nc(-c3ccccc3)cc(O)c12 nan
CHEMBL1486764 40946 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 2 1 4 4.4 Cc1nc(-c2ccccc2)nc2nc(-c3ccccc3)cc(O)c12 nan
702036 41023 13 None -19 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 1 0 5 4.2 N#Cc1c2c(c(-n3cnc4ccccc43)n3c1nc1ccccc13)CCC2 nan
CHEMBL1487421 41023 13 None -19 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 1 0 5 4.2 N#Cc1c2c(c(-n3cnc4ccccc43)n3c1nc1ccccc13)CCC2 nan
15989752 41043 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.9 Cc1ccc2nc(NCCc3ccc(Cl)cc3)c3nncn3c2c1 nan
CHEMBL1487625 41043 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 4 1 5 3.9 Cc1ccc2nc(NCCc3ccc(Cl)cc3)c3nncn3c2c1 nan
16008663 41056 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 8 1.6 COC(=O)c1ccc(NC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1487699 41056 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 5 1 8 1.6 COC(=O)c1ccc(NC(=O)CCc2c(C)nc3c(c2C)c(=O)n(C)c(=O)n3C)cc1 nan
16025367 41152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 7 1 7 5.4 COc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)cc1 nan
CHEMBL1488348 41152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 570 7 1 7 5.4 COc1ccc(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)cc1 nan
4611609 41158 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 3 6.2 CCc1ccc(OCC(=O)Nc2ccc3c(c2)c2ccccc2n3CC)c(Br)c1 nan
CHEMBL1488388 41158 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 6 1 3 6.2 CCc1ccc(OCC(=O)Nc2ccc3c(c2)c2ccccc2n3CC)c(Br)c1 nan
1726407 41179 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 4 6.4 CCOc1cccc(C(=O)Nc2ccc3oc(-c4ccc(C(C)(C)C)cc4)nc3c2)c1 nan
CHEMBL1488581 41179 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 1 4 6.4 CCOc1cccc(C(=O)Nc2ccc3oc(-c4ccc(C(C)(C)C)cc4)nc3c2)c1 nan
16030737 41215 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 10 2.0 Cc1ccc(-c2nc(SCC(=O)Nc3cc(C)on3)c3c(=O)n(C)c(=O)n(C)c3n2)cc1 nan
CHEMBL1488787 41215 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 10 2.0 Cc1ccc(-c2nc(SCC(=O)Nc3cc(C)on3)c3c(=O)n(C)c(=O)n(C)c3n2)cc1 nan
824820 41264 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 5 3.1 Cc1ccc(-n2c(N)c(C#N)c(-c3ccccc3)c(C#N)c2=O)cc1 nan
CHEMBL1489157 41264 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 2 1 5 3.1 Cc1ccc(-n2c(N)c(C#N)c(-c3ccccc3)c(C#N)c2=O)cc1 nan
2036296 41305 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 6 4.0 CCCCn1c(-c2cccs2)nc2oc3ccccc3c(=O)c2c1=O nan
CHEMBL1489469 41305 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 6 4.0 CCCCn1c(-c2cccs2)nc2oc3ccccc3c(=O)c2c1=O nan
3448820 41361 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 0 4 4.8 COc1cc2c(cc1OC)C(COc1ccc(F)cc1)N(C(=O)c1ccccc1F)CC2 nan
CHEMBL1489934 41361 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 0 4 4.8 COc1cc2c(cc1OC)C(COc1ccc(F)cc1)N(C(=O)c1ccccc1F)CC2 nan
655760 41436 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 4 3.0 Cc1ccc(C)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c1 nan
CHEMBL1490512 41436 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 4 3.0 Cc1ccc(C)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c1 nan
16007588 41468 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 5 4.1 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCCc1ccc(Cl)cc1)cn2C nan
CHEMBL1490705 41468 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 515 7 1 5 4.1 CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)c(=O)c(C(=O)NCCc1ccc(Cl)cc1)cn2C nan
1483825 41475 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.3 FC(F)(F)c1cnc(-c2cnc(-c3cccnc3)nc2)c(Cl)c1 nan
CHEMBL1490743 41475 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 2 0 4 4.3 FC(F)(F)c1cnc(-c2cnc(-c3cccnc3)nc2)c(Cl)c1 nan
16194118 41501 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 2.0 CCOC(=O)c1ccc(NC(=S)N2CCN(c3ccc(N4CCOCC4)nn3)CC2)cc1 nan
CHEMBL1490926 41501 8 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 2.0 CCOC(=O)c1ccc(NC(=S)N2CCN(c3ccc(N4CCOCC4)nn3)CC2)cc1 nan
4578555 41522 17 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCCC1 nan
CHEMBL1491054 41522 17 None -7 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 4 1 5 3.9 O=C(CSc1ncnc2c1oc1ccccc12)NC1CCCCC1 nan
1147591 41583 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
CHEMBL1491533 41583 19 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 4 1 6 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1 nan
761949 41716 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.7 CC(=O)c1cnc2cc(-c3cccc(Br)c3)nn2c1C nan
CHEMBL1492474 41716 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 329 2 0 4 3.7 CC(=O)c1cnc2cc(-c3cccc(Br)c3)nn2c1C nan
16031672 41765 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 2 4 2.8 O=C(Nc1ccc(F)cc1F)C1CCN(S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)CC1 nan
CHEMBL1492791 41765 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 4 2 4 2.8 O=C(Nc1ccc(F)cc1F)C1CCN(S(=O)(=O)c2ccc3[nH]c(=O)ccc3c2)CC1 nan
3496289 41798 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 11 2 7 3.7 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCCOC)cc3)c(=O)c2cc1OCC nan
CHEMBL1493174 41798 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 11 2 7 3.7 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCCOC)cc3)c(=O)c2cc1OCC nan
16033055 41811 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 10 0 11 3.4 CCOc1ccc(C(=O)Cn2c(=O)n3nc(CCn4nc(C)cc4C)nc3c3cc(OC)c(OC)cc32)cc1 nan
CHEMBL1493282 41811 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 10 0 11 3.4 CCOc1ccc(C(=O)Cn2c(=O)n3nc(CCn4nc(C)cc4C)nc3c3cc(OC)c(OC)cc32)cc1 nan
6324582 41865 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 3.7 Cc1ccc2cc(CCNC(=O)CC(C)(C)C)c(O)nc2c1C nan
CHEMBL1493825 41865 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 3.7 Cc1ccc2cc(CCNC(=O)CC(C)(C)C)c(O)nc2c1C nan
2337492 41935 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 5 5.2 CCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(C)cc1)c1ccccc12 nan
CHEMBL1494522 41935 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 1 5 5.2 CCOC(=O)c1c(C)oc2c1cc(NS(=O)(=O)c1ccc(C)cc1)c1ccccc12 nan
16030367 42004 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 5.5 CCc1ccccc1NC(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1 nan
CHEMBL1495193 42004 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 8 1 5 5.5 CCc1ccccc1NC(=O)CSc1nc2ccccc2nc1Cc1cccc(OC)c1 nan
659270 42010 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 1 8 2.7 CCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OC)cc2)c1C#N nan
CHEMBL1495223 42010 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 1 8 2.7 CCOC(=O)CSc1nc(N)c(C#N)c(-c2ccc(OC)cc2)c1C#N nan
1473491 42011 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 0 4 4.3 O=C1c2ccccc2C(=O)N1CCc1csc(-c2cccc(Cl)c2)n1 nan
CHEMBL1495238 42011 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 4 0 4 4.3 O=C1c2ccccc2C(=O)N1CCc1csc(-c2cccc(Cl)c2)n1 nan
803577 42034 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.6 CC(=O)c1sc(NC(=O)c2ccc3c(c2)OCO3)nc1C nan
CHEMBL1495561 42034 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.6 CC(=O)c1sc(NC(=O)c2ccc3c(c2)OCO3)nc1C nan
16015766 42041 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 2 4.9 CC(C)CC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)c1 nan
CHEMBL1495596 42041 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 2 2 4.9 CC(C)CC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3[nH]2)c1 nan
1394903 42051 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 6 0 5 4.9 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Br)cc1 nan
CHEMBL1495702 42051 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 519 6 0 5 4.9 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Br)cc1 nan
9550975 42134 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 6 4.1 COc1ccccc1CNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1496499 42134 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 6 4.1 COc1ccccc1CNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C nan
7190533 42171 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 6 3.8 Cc1ccccc1CSc1ccc2nnc(-c3ccccn3)n2n1 nan
CHEMBL1496795 42171 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 0 6 3.8 Cc1ccccc1CSc1ccc2nnc(-c3ccccn3)n2n1 nan
22548523 42184 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.8 CN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(O)ccc2c1 nan
CHEMBL1496881 42184 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 4 2.8 CN(Cc1ccccc1)S(=O)(=O)c1ccc2nc(O)ccc2c1 nan
16030464 42199 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 4 5.1 COc1ccccc1C(=O)Nc1ccccc1SCc1cc(=O)c2ccccc2[nH]1 nan
CHEMBL1497018 42199 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 6 2 4 5.1 COc1ccccc1C(=O)Nc1ccccc1SCc1cc(=O)c2ccccc2[nH]1 nan
3282397 42229 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 3.8 CCOc1ccc(-n2nc(C(=O)NC3CCCCC3)c3ccccc3c2=O)cc1 nan
CHEMBL1497244 42229 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 391 5 1 5 3.8 CCOc1ccc(-n2nc(C(=O)NC3CCCCC3)c3ccccc3c2=O)cc1 nan
2190255 42235 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 3 6 -0.1 CCN1C(=O)/C(=C/Nc2ccc(S(N)(=O)=O)cc2)C(=O)NC1=S nan
CHEMBL1497307 42235 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 3 6 -0.1 CCN1C(=O)/C(=C/Nc2ccc(S(N)(=O)=O)cc2)C(=O)NC1=S nan
860457 42306 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 6 2.6 CSc1nnc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)o1 nan
CHEMBL1497958 42306 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 4 0 6 2.6 CSc1nnc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)o1 nan
2815318 42385 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 7 2.2 CCOC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O nan
CHEMBL1498797 42385 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 0 7 2.2 CCOC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O nan
2126242 42389 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.3 COc1ccc2c(C)cc(SCC(=O)Nc3cccnc3Cl)nc2c1 nan
CHEMBL1498813 42389 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 5 4.3 COc1ccc2c(C)cc(SCC(=O)Nc3cccnc3Cl)nc2c1 nan
1105537 42478 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 6 3.2 CCOC(=O)/C(C#N)=C/c1ccc(OCC(=O)Nc2ccccc2)c(OC)c1 nan
CHEMBL1499500 42478 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 8 1 6 3.2 CCOC(=O)/C(C#N)=C/c1ccc(OCC(=O)Nc2ccccc2)c(OC)c1 nan
649649 42491 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 6 2.0 Cc1ccnc(N2CCC(C(=O)NCc3ccc4c(c3)OCO4)CC2)n1 nan
CHEMBL1499616 42491 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 4 1 6 2.0 Cc1ccnc(N2CCC(C(=O)NCc3ccc4c(c3)OCO4)CC2)n1 nan
866361 42492 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1Cc1ccc2c(c1)OCO2 nan
CHEMBL1499629 42492 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 5 2.8 O=c1c2ccccc2[nH]c(=S)n1Cc1ccc2c(c1)OCO2 nan
2764824 42518 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 2 2.8 CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1 nan
CHEMBL1499851 42518 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 3 2 2 2.8 CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1 nan
852955 42553 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 4 5.0 Cc1sc2nc(Cc3ccccc3)nc(O)c2c1-c1ccccc1 nan
CHEMBL1500159 42553 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 3 1 4 5.0 Cc1sc2nc(Cc3ccccc3)nc(O)c2c1-c1ccccc1 nan
135415434 42709 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 7 2.3 Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nc(O)c4ccccc4n3)CC2)cc1 nan
CHEMBL1501602 42709 7 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 5 1 7 2.3 Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nc(O)c4ccccc4n3)CC2)cc1 nan
54676936 42730 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 2 4 3.0 O=C(Nc1cccc(F)c1)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
CHEMBL1501763 42730 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 2 2 4 3.0 O=C(Nc1cccc(F)c1)c1c(O)c2cccc3c2n(c1=O)CCC3 nan
1176241 42787 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 6 4.5 CCOc1ccc2nc(SCC(=O)Nc3ccc(S(=O)(=O)N4CCCC4)cc3)c(C)cc2c1 nan
CHEMBL1502202 42787 5 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 8 1 6 4.5 CCOc1ccc2nc(SCC(=O)Nc3ccc(S(=O)(=O)N4CCCC4)cc3)c(C)cc2c1 nan
734457 42886 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 257 3 1 5 2.6 COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 nan
CHEMBL1503104 42886 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 257 3 1 5 2.6 COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 nan
2515869 42910 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 2.9 CCC(=O)c1ccc(OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 nan
CHEMBL1503299 42910 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 2.9 CCC(=O)c1ccc(OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 nan
5310469 42940 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 0 8 3.3 COc1ccc(-c2nnc3ccc(SCC(=O)N4CCCCCC4)nn23)cc1OC nan
CHEMBL1503498 42940 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 0 8 3.3 COc1ccc(-c2nnc3ccc(SCC(=O)N4CCCCCC4)nn23)cc1OC nan
3574258 42948 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccc(Cl)cc1 nan
CHEMBL1503560 42948 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 5 2 6 3.1 O=C(CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)NCc1ccc(Cl)cc1 nan
1859366 42953 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 4 5.0 Cc1ccc(S(=O)(=O)N(Cc2cc3ccc(C)cc3nc2O)c2ccccc2)cc1 nan
CHEMBL1503583 42953 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 5 1 4 5.0 Cc1ccc(S(=O)(=O)N(Cc2cc3ccc(C)cc3nc2O)c2ccccc2)cc1 nan
664334 43058 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 0 4 4.2 O=C1CC(c2ccc(F)cc2)Cc2nc(N3CCc4ccccc43)ncc21 nan
CHEMBL1504653 43058 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 0 4 4.2 O=C1CC(c2ccc(F)cc2)Cc2nc(N3CCc4ccccc43)ncc21 nan
2980439 43117 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 7 2 4 3.2 CCc1ccc(N2CCN(CCNC(=O)Nc3ccc(OC)cc3)CC2)cc1 nan
CHEMBL1505203 43117 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 7 2 4 3.2 CCc1ccc(N2CCN(CCNC(=O)Nc3ccc(OC)cc3)CC2)cc1 nan
661657 43127 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 0 7 3.3 O=C1c2ccccc2C(=O)N1Cc1nn2c(-c3ccc(Cl)cc3)nnc2s1 nan
CHEMBL1505268 43127 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 0 7 3.3 O=C1c2ccccc2C(=O)N1Cc1nn2c(-c3ccc(Cl)cc3)nnc2s1 nan
12006071 43145 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 0 6 4.5 O=C(CSc1ccc2nnc(-c3ccc(Cl)cc3)n2n1)N1CCCc2ccccc21 nan
CHEMBL1505466 43145 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 0 6 4.5 O=C(CSc1ccc2nnc(-c3ccc(Cl)cc3)n2n1)N1CCCc2ccccc21 nan
834457 43209 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 2.7 NS(=O)(=O)c1ccc(NCc2c(F)cccc2Cl)cc1 nan
CHEMBL1505860 43209 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 2 3 2.7 NS(=O)(=O)c1ccc(NCc2c(F)cccc2Cl)cc1 nan
1804684 43215 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.8 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N nan
CHEMBL1505914 43215 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 5 3.8 COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2C)c1C#N nan
3882765 43244 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 2 1 3.9 Cc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c1 nan
CHEMBL1506222 43244 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 268 2 2 1 3.9 Cc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c1 nan
3795359 43283 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.8 CCC(C)c1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1 nan
CHEMBL1506487 43283 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 6 3.8 CCC(C)c1ccc(-n2c(=O)c3ccccc3n3c(S)nnc23)cc1 nan
4118928 43288 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 7 2 5 2.1 CCCCOCCCN1C(C)=CC(=C2C(=O)NC(=S)NC2=O)C=C1C nan
CHEMBL1506535 43288 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 7 2 5 2.1 CCCCOCCCN1C(C)=CC(=C2C(=O)NC(=S)NC2=O)C=C1C nan
1078308 43344 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3ccccc3C)c(=O)c2c1C nan
CHEMBL1507058 43344 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 6 4.4 COc1ccccc1NC(=O)c1sc2ncn(Cc3ccccc3C)c(=O)c2c1C nan
1390207 43352 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 0 5 4.8 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Cl)cc1 nan
CHEMBL1507117 43352 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 6 0 5 4.8 O=S(=O)([N-]c1nc2ccccc2nc1-[n+]1ccn(Cc2ccccc2)c1)c1ccc(Cl)cc1 nan
9550860 43370 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 3 2.0 Cc1ccc(OC(=O)c2ccccc2P(=O)(O)O)cc1 nan
CHEMBL1507343 43370 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 2 3 2.0 Cc1ccc(OC(=O)c2ccccc2P(=O)(O)O)cc1 nan
2810073 43382 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.3 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 nan
CHEMBL1507430 43382 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 2 1 6 3.3 Cc1csc2c(=O)sc(NC(=O)c3cccs3)nc12 nan
20874463 43447 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 4.1 Cc1ccc(-c2nnn3c2nc(NC(C)C)c2ccccc23)cc1 nan
CHEMBL1507945 43447 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 5 4.1 Cc1ccc(-c2nnn3c2nc(NC(C)C)c2ccccc23)cc1 nan
5875901 43466 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 3.8 CCOC(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)Oc2ccccc21 nan
CHEMBL1508095 43466 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 3.8 CCOC(=O)CN1C(=O)/C(=C/c2cccc(Br)c2)Oc2ccccc21 nan
649082 43497 2 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 2 7 2.6 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccco2)n1)NC1CCCCC1 nan
CHEMBL1508376 43497 2 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 6 2 7 2.6 O=C(Cn1nnc(-c2ccccc2NC(=O)c2ccco2)n1)NC1CCCCC1 nan
1735895 43800 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 7 3.2 CCc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
CHEMBL1511120 43800 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 7 2 7 3.2 CCc1ccc(OCC(=O)NNC(=O)CSc2ncnc3sc(C)c(C)c23)cc1 nan
1186303 43825 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 2 6 3.3 CN(C)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3nccs3)cc2)cc1 nan
CHEMBL1511271 43825 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 2 6 3.3 CN(C)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3nccs3)cc2)cc1 nan
2815635 43861 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 2 4 5.7 O=C(Nc1ccccc1)Nc1sccc1-c1nc2ccccc2s1 nan
CHEMBL1511507 43861 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 3 2 4 5.7 O=C(Nc1ccccc1)Nc1sccc1-c1nc2ccccc2s1 nan
661880 43863 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 0 6 2.3 N#CCc1nc2c3c4c(sc3ncn2n1)CCCC4 nan
CHEMBL1511519 43863 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 269 1 0 6 2.3 N#CCc1nc2c3c4c(sc3ncn2n1)CCCC4 nan
4604131 43906 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 7 3.9 COc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3ccsc3c2=O)cc1 nan
CHEMBL1512120 43906 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 1 7 3.9 COc1ccc(-n2c(SCC(=O)NCc3ccccc3)nc3ccsc3c2=O)cc1 nan
16027453 43938 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1ccccc1C(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1512551 43938 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 6 1 8 3.7 COc1ccccc1C(=O)Nc1ccccc1C(=O)OCc1cc(=O)n2c(C)csc2n1 nan
16018474 43940 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 5.8 CCc1ccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)cc1 nan
CHEMBL1512597 43940 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 4 1 4 5.8 CCc1ccc(-c2cn3c(n2)sc2cc(C(=O)NC4CCCCC4)ccc23)cc1 nan
16030606 43942 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4cccc(C)c4n3)c2)c1 nan
CHEMBL1512611 43942 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 1 5 4.1 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4cccc(C)c4n3)c2)c1 nan
16030447 43943 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4ccccc4Cl)c3)cc(=O)n2c1 nan
CHEMBL1512613 43943 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4ccccc4Cl)c3)cc(=O)n2c1 nan
7245878 43950 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 6 2.6 COc1ccc(S(=O)(=O)c2cc3cc(OC)ccc3oc2=O)cc1 nan
CHEMBL1512705 43950 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 0 6 2.6 COc1ccc(S(=O)(=O)c2cc3cc(OC)ccc3oc2=O)cc1 nan
16020157 43970 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 9 3.6 CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c2nc(-c3ccccc3)nn12 nan
CHEMBL1512982 43970 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 7 0 9 3.6 CCOC(=O)CSc1nc2cc(OC)c(OC)cc2c2nc(-c3ccccc3)nn12 nan
16023839 43971 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 3 0 6 4.0 CN1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2C2CCN(C(=O)OC(C)(C)C)CC2)CC1 nan
CHEMBL1513006 43971 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 487 3 0 6 4.0 CN1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2C2CCN(C(=O)OC(C)(C)C)CC2)CC1 nan
3402023 43973 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 8 2 5 5.4 COc1ccc(CNC(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(C)=O)c2)c(OC)c1 nan
CHEMBL1513023 43973 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 8 2 5 5.4 COc1ccc(CNC(=O)c2ccc(Sc3ccc(Cl)cc3)c(NC(C)=O)c2)c(OC)c1 nan
16014785 43974 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 2 6 4.5 COC(=O)c1ccc(NC(=O)CSc2nc(C)cc(C)c2C(=O)Nc2ccccc2)cc1 nan
CHEMBL1513057 43974 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 2 6 4.5 COC(=O)c1ccc(NC(=O)CSc2nc(C)cc(C)c2C(=O)Nc2ccccc2)cc1 nan
16021019 43976 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(CSc2nc3cccnc3n2Cc2ccc(F)cc2)cc1 nan
CHEMBL1513070 43976 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 7 1 5 6.0 O=C(NC1CCCCC1)c1ccc(CSc2nc3cccnc3n2Cc2ccc(F)cc2)cc1 nan
16008530 43982 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 5 6.0 CSc1ccc(CCNC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccc(C)c(C)c3)c2C)cc1 nan
CHEMBL1513168 43982 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 5 6.0 CSc1ccc(CCNC(=O)CCc2c(C)nc3c(c(C)nn3-c3ccc(C)c(C)c3)c2C)cc1 nan
16018739 43993 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.0 O=C(CCn1c(=O)c2cccn2c2cccnc21)NCc1ccc(Cl)cc1 nan
CHEMBL1513371 43993 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 5 1 5 3.0 O=C(CCn1c(=O)c2cccn2c2cccnc21)NCc1ccc(Cl)cc1 nan
16030719 43996 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 9 2.0 Cc1cccc(-c2nc(SCC(=O)NCc3ccco3)c3c(=O)n(C)c(=O)n(C)c3n2)c1 nan
CHEMBL1513435 43996 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 9 2.0 Cc1cccc(-c2nc(SCC(=O)NCc3ccco3)c3c(=O)n(C)c(=O)n(C)c3n2)c1 nan
16025371 43998 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 568 6 1 6 6.0 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)c1 nan
CHEMBL1513466 43998 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 568 6 1 6 6.0 Cc1ccc(C)c(NC(=O)CSc2ncc3c(n2)-c2cc(Cl)ccc2N(Cc2ccccc2F)S3(=O)=O)c1 nan
16026779 44002 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 8 2.8 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1513507 44002 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 444 6 1 8 2.8 O=C(CNC(=O)c1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16024940 44004 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 4.9 O=C(NCCc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
CHEMBL1513535 44004 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 4 4.9 O=C(NCCc1ccccc1Cl)C1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 nan
1316309 44016 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1ccc2oc(-c3ccc(Cl)c(NC(=O)Cc4ccccc4)c3)nc2c1 nan
CHEMBL1513652 44016 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 1 3 5.6 Cc1ccc2oc(-c3ccc(Cl)c(NC(=O)Cc4ccccc4)c3)nc2c1 nan
16025593 44031 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 3 0 8 3.9 Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccc(Br)cc1F nan
CHEMBL1514000 44031 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 3 0 8 3.9 Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccc(Br)cc1F nan
15989077 44046 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 10 1 8 4.8 Cc1cc(C)c(Cn2c(=O)n(CCCCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
CHEMBL1514246 44046 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 547 10 1 8 4.8 Cc1cc(C)c(Cn2c(=O)n(CCCCCC(=O)NCc3ccc4c(c3)OCO4)c(=O)c3sccc32)c(C)c1 nan
2689697 44051 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 3.2 COc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1OC nan
CHEMBL1514340 44051 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 339 6 1 5 3.2 COc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1OC nan
24982480 44064 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 5 2.3 CCN(Cc1ccccc1)C(=O)Cc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 nan
CHEMBL1514540 44064 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 0 5 2.3 CCN(Cc1ccccc1)C(=O)Cc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 nan
16015735 44089 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 3 3 9 2.5 COC(=O)c1c(C)sc(-c2c(-c3ccc4c(c3)OCCO4)[nH]c3c2c(=O)[nH]c(=O)n3C)c1O nan
CHEMBL1514818 44089 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 3 3 9 2.5 COC(=O)c1c(C)sc(-c2c(-c3ccc4c(c3)OCCO4)[nH]c3c2c(=O)[nH]c(=O)n3C)c1O nan
16022151 44093 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 6 2.5 COc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1C)n2C nan
CHEMBL1514879 44093 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 0 6 2.5 COc1ccc2c(c1)c1c(c(=O)n(-c3ccccc3C)c(=O)n1C)n2C nan
16009667 44101 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 5 4.5 O=c1c2sc3ccccc3c2n(Cc2ccccc2)c(=O)n1Cc1ccccc1 nan
CHEMBL1515036 44101 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 0 5 4.5 O=c1c2sc3ccccc3c2n(Cc2ccccc2)c(=O)n1Cc1ccccc1 nan
5167801 44104 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 O=C(NC1CCCCC1)c1cc(Nc2ccccc2)nc2ccccc12 nan
CHEMBL1515050 44104 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 O=C(NC1CCCCC1)c1cc(Nc2ccccc2)nc2ccccc12 nan
16030854 44106 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 2 4 5.0 CC(NC(=O)c1ccc(NC(=O)c2nsc3ccccc23)cc1)c1ccccc1 nan
CHEMBL1515130 44106 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 2 4 5.0 CC(NC(=O)c1ccc(NC(=O)c2nsc3ccccc23)cc1)c1ccccc1 nan
135416423 44127 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 4 4.7 CCc1ccc2oc(-c3cc(NC(=O)C(C)C)cc(C)c3O)nc2c1 nan
CHEMBL1515394 44127 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 338 4 2 4 4.7 CCc1ccc2oc(-c3cc(NC(=O)C(C)C)cc(C)c3O)nc2c1 nan
8057488 44149 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 5.4 Cc1cc2nc(-c3ccc(OCc4ccccc4F)cc3)cc(C(F)(F)F)n2n1 nan
CHEMBL1515771 44149 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 4 0 4 5.4 Cc1cc2nc(-c3ccc(OCc4ccccc4F)cc3)cc(C(F)(F)F)n2n1 nan
4154278 44151 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1C nan
CHEMBL1515779 44151 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 5.2 Cc1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1C nan
16017003 44177 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 4 4.5 CCOc1ccccc1NC(=O)C(=O)c1cc(C)n(-c2ccc(F)cc2)c1C nan
CHEMBL1516117 44177 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 380 6 1 4 4.5 CCOc1ccccc1NC(=O)C(=O)c1cc(C)n(-c2ccc(F)cc2)c1C nan
7343169 44188 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 5 4.9 CCOC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 nan
CHEMBL1516275 44188 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 4 0 5 4.9 CCOC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 nan
3586950 44196 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 6 4.6 O=C(CSc1nc2ccsc2c(=O)n1-c1ccc(Br)cc1)NCc1ccccc1 nan
CHEMBL1516478 44196 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 6 4.6 O=C(CSc1nc2ccsc2c(=O)n1-c1ccc(Br)cc1)NCc1ccccc1 nan
3206747 44337 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 COc1cccc(CC(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)c1 nan
CHEMBL1517888 44337 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 4 1 5 3.5 COc1cccc(CC(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)c1 nan
985821 44341 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1cc(F)cc(F)c1)c1sc(Cl)nc1-c1ccccc1 nan
CHEMBL1517907 44341 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 1 3 5.0 O=C(Nc1cc(F)cc(F)c1)c1sc(Cl)nc1-c1ccccc1 nan
1093907 44342 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 7 1.5 CNS(=O)(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 nan
CHEMBL1517917 44342 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 5 2 7 1.5 CNS(=O)(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 nan
15991337 44365 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 0 7 4.8 CCc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1518140 44365 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 4 0 7 4.8 CCc1ccc(C2c3c(oc4ccc(F)cc4c3=O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
16011836 44407 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 5.0 COc1ccc(CSc2nc3ccncc3n2CC(=O)Nc2cc(C)cc(C)c2)cc1 nan
CHEMBL1518592 44407 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 6 5.0 COc1ccc(CSc2nc3ccncc3n2CC(=O)Nc2cc(C)cc(C)c2)cc1 nan
1086869 44456 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 6 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)c(OC)c1 nan
CHEMBL1518977 44456 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 6 1 6 3.4 COc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)c(OC)c1 nan
730225 44469 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 2 6 2.2 N#CCc1c(C#N)c(N)nc(Nc2ccccc2)c1C#N nan
CHEMBL1519080 44469 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 274 3 2 6 2.2 N#CCc1c(C#N)c(N)nc(Nc2ccccc2)c1C#N nan
1008965 44481 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 4 6.1 CC(=O)c1cccc(NC(=O)c2cc(-c3ccc(Cl)s3)nc3ccccc23)c1 nan
CHEMBL1519196 44481 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 4 1 4 6.1 CC(=O)c1cccc(NC(=O)c2cc(-c3ccc(Cl)s3)nc3ccccc23)c1 nan
16025959 44564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 8 1.6 O=C(NCCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1519916 44564 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 8 1.6 O=C(NCCc1ccc(Cl)cc1)c1cnc2sc(N3CCOCC3)nn2c1=O nan
2740242 44571 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 2 2 4 3.1 Cc1noc(C(F)(F)F)c1C(=O)NNC(=O)c1cccc(C(F)(F)F)c1 nan
CHEMBL1519973 44571 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 2 2 4 3.1 Cc1noc(C(F)(F)F)c1C(=O)NNC(=O)c1cccc(C(F)(F)F)c1 nan
16020184 44664 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 8 0 9 5.3 COc1cc2nc(SCc3cccc(Cl)c3)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
CHEMBL1520786 44664 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 508 8 0 9 5.3 COc1cc2nc(SCc3cccc(Cl)c3)n3nc(CCn4nc(C)cc4C)nc3c2cc1OC nan
15989989 44667 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 8 2 9 3.4 COc1ccc(CCNC(=O)c2ccc(Nc3nc4ccccc4n4nnnc34)cc2)cc1OC nan
CHEMBL1520796 44667 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 8 2 9 3.4 COc1ccc(CCNC(=O)c2ccc(Nc3nc4ccccc4n4nnnc34)cc2)cc1OC nan
742057 44708 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 6 3.1 O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1ccco1 nan
CHEMBL1521136 44708 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 6 3.1 O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1ccco1 nan
16026879 44736 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 6 4.4 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(SC)cc4)cc3c2=O)cc1 nan
CHEMBL1521365 44736 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 7 1 6 4.4 COc1ccc(Cn2ccc3nc(C)c(C(=O)NCc4ccc(SC)cc4)cc3c2=O)cc1 nan
1164118 44749 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 0 7 3.4 COc1ccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)cc1OC nan
CHEMBL1521488 44749 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 0 7 3.4 COc1ccc(-c2nnc(SCC(=O)N3CCc4ccccc43)o2)cc1OC nan
3146504 44804 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
CHEMBL1521972 44804 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 5 1 6 2.9 CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
16021952 44836 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 7 1 7 3.9 CCc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3c2c2cc(OC)ccc2n3C)c1 nan
CHEMBL1522220 44836 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 496 7 1 7 3.9 CCc1cccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3c2c2cc(OC)ccc2n3C)c1 nan
4090626 44888 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 4 5.8 CCOc1ccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc3c2CCCCC3)cc1 nan
CHEMBL1522769 44888 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 7 2 4 5.8 CCOc1ccc(NC(=O)c2c(NC(=O)Cc3ccccc3)sc3c2CCCCC3)cc1 nan
3148294 44894 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 6 4.1 CC(C)CNC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
CHEMBL1522819 44894 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 7 1 6 4.1 CC(C)CNC(=O)CCSc1nc(-c2ccc3c(c2)OCO3)cc(C(F)(F)F)n1 nan
16030650 44918 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 5 0 8 3.0 O=c1cc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)nc2sc(-c3ccccc3Cl)nn12 nan
CHEMBL1522977 44918 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 5 0 8 3.0 O=c1cc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)nc2sc(-c3ccccc3Cl)nn12 nan
16026964 44960 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccccc1F)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
CHEMBL1523393 44960 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 9 3.1 O=C(COc1ccccc1F)OCc1cc(=O)n2nc(-c3cccs3)sc2n1 nan
16027395 44984 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 10 3.4 CCOCCc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
CHEMBL1523585 44984 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 10 3.4 CCOCCc1nn2c(=O)cc(COC(=O)c3ccccc3NC(=O)c3cccs3)nc2s1 nan
2465708 44993 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 6 1 9 4.8 COc1ccccc1-n1c(=O)c(C#N)c(-c2ccc([N+](=O)[O-])cc2)c2cc(C(=O)c3ccccc3O)cnc21 nan
CHEMBL1523696 44993 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 518 6 1 9 4.8 COc1ccccc1-n1c(=O)c(C#N)c(-c2ccc([N+](=O)[O-])cc2)c2cc(C(=O)c3ccccc3O)cnc21 nan
1465904 45010 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 1 7 4.8 CCc1nnc(NC(=O)CSc2nc(C3CCCCC3)nc3ccccc23)s1 nan
CHEMBL1523892 45010 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 1 7 4.8 CCc1nnc(NC(=O)CSc2nc(C3CCCCC3)nc3ccccc23)s1 nan
7422674 45011 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 3 4.2 O=C(Nc1ccccc1C(F)(F)F)c1cccn(Cc2ccccc2)c1=O nan
CHEMBL1523907 45011 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 4 1 3 4.2 O=C(Nc1ccccc1C(F)(F)F)c1cccn(Cc2ccccc2)c1=O nan
15989150 45055 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 6 3.6 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccc(C)cc2)c1=O nan
CHEMBL1524350 45055 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 471 9 1 6 3.6 COc1ccccc1CNC(=O)CCCn1c(=O)c2ccccc2n(Cc2ccc(C)cc2)c1=O nan
2548636 45139 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 3 7 2.5 Cc1nc(SCC(=O)Nc2cc(C(N)=O)cc(C(N)=O)c2)c2c(C)c(C)sc2n1 nan
CHEMBL1525189 45139 5 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 6 3 7 2.5 Cc1nc(SCC(=O)Nc2cc(C(N)=O)cc(C(N)=O)c2)c2c(C)c(C)sc2n1 nan
15989883 45143 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 3 5.4 Cc1c(C(=O)OC2CCCCC2)[nH]c2c1C(=O)CC(c1ccccc1Cl)C2 nan
CHEMBL1525262 45143 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 3 1 3 5.4 Cc1c(C(=O)OC2CCCCC2)[nH]c2c1C(=O)CC(c1ccccc1Cl)C2 nan
1186420 45186 10 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 7 3.8 Clc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
CHEMBL1525610 45186 10 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 7 3.8 Clc1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 nan
4154665 45190 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 2 7 3.3 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCOC)cc3)c(=O)c2cc1OCC nan
CHEMBL1525634 45190 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 10 2 7 3.3 CCOc1cc2[nH]c(=S)n(Cc3ccc(C(=O)NCCOC)cc3)c(=O)c2cc1OCC nan
135460528 45245 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 2 5 3.5 Cc1ccc(N2C(=O)NC(=O)/C(=C/Nc3ncc(Br)cc3Br)C2=O)cc1 nan
CHEMBL1526117 45245 7 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 478 3 2 5 3.5 Cc1ccc(N2C(=O)NC(=O)/C(=C/Nc3ncc(Br)cc3Br)C2=O)cc1 nan
579848 45303 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 1 3 4.7 O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1F nan
CHEMBL1526496 45303 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 336 4 1 3 4.7 O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1F nan
16018883 45364 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 4 4.6 Cc1ccc(C)c(NC(=O)CCCN2C(=O)C(c3ccccc3)Oc3cccnc32)c1 nan
CHEMBL1527105 45364 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 6 1 4 4.6 Cc1ccc(C)c(NC(=O)CCCN2C(=O)C(c3ccccc3)Oc3cccnc32)c1 nan
2765322 45410 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 7 1.1 N#Cc1cc(C#N)c(N2CCN(c3ccccn3)CC2)nc1N nan
CHEMBL1527484 45410 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 305 2 1 7 1.1 N#Cc1cc(C#N)c(N2CCN(c3ccccn3)CC2)nc1N nan
16009430 45443 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.7 CCC(CC)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
CHEMBL1527797 45443 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 3.7 CCC(CC)C(=O)Nc1ccc(OCc2cc(=O)n3ccsc3n2)cc1 nan
16015678 45444 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CCC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
CHEMBL1527810 45444 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 7 1 5 5.1 CCC(=O)Nc1ccc2nc(SCCOc3ccc(C)cc3)sc2c1 nan
16009490 45492 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
CHEMBL1528261 45492 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 5 1 6 4.2 Cc1cccc(C(=O)Nc2cccc(OCc3cc(=O)n4c(C)csc4n3)c2)c1 nan
16016701 45495 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 2.6 COC(=O)c1ccccc1NC(=O)CCC(=O)N1CCOc2ccccc21 nan
CHEMBL1528274 45495 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 5 1 5 2.6 COC(=O)c1ccccc1NC(=O)CCC(=O)N1CCOc2ccccc21 nan
16391033 45511 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 3 3.8 COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cn1 nan
CHEMBL1528436 45511 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 3 1 3 3.8 COc1cc2ccccc2cc1C(=O)Nc1ccc(C)cn1 nan
7185472 45533 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 2 6 2.6 CCOC(=O)c1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 nan
CHEMBL1528587 45533 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 6 2 6 2.6 CCOC(=O)c1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 nan
5310045 45587 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 5 4.2 Cc1c(C(=O)Nc2ccncc2)sc2nc(-c3ccc(F)cc3)cn12 nan
CHEMBL1529086 45587 11 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 3 1 5 4.2 Cc1c(C(=O)Nc2ccncc2)sc2nc(-c3ccc(F)cc3)cn12 nan
5146627 45625 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 0 6 5.1 COCCN(CCOC)c1ncnc2c1c(-c1ccccc1)cn2-c1ccc(C)c(Cl)c1 nan
CHEMBL1529403 45625 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 9 0 6 5.1 COCCN(CCOC)c1ncnc2c1c(-c1ccccc1)cn2-c1ccc(C)c(Cl)c1 nan
5181996 45639 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 4 0 6 1.0 CCOC(=O)Cc1nc2ccccc2n(CC#N)c1=O nan
CHEMBL1529516 45639 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 271 4 0 6 1.0 CCOC(=O)Cc1nc2ccccc2n(CC#N)c1=O nan
2099952 45666 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 4.9 Oc1nc(Cc2ccc(F)cc2)nc2scc(-c3ccc(F)cc3)c12 nan
CHEMBL1529751 45666 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 4.9 Oc1nc(Cc2ccc(F)cc2)nc2scc(-c3ccc(F)cc3)c12 nan
4373285 45694 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1Br nan
CHEMBL1529998 45694 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 4 1 4 6.7 COc1ccc(C(=O)Nc2ccc3oc(-c4ccc5ccccc5c4)nc3c2)cc1Br nan
16024591 45739 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCCc3ccccc3)c2n1 nan
CHEMBL1530480 45739 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 7 1 5 3.4 Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(=O)NCCc3ccccc3)c2n1 nan
4994836 45890 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 Cc1ccccc1Nc1cc(C(=O)NC2CCCC2)c2ccccc2n1 nan
CHEMBL1531717 45890 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 4 2 3 5.0 Cc1ccccc1Nc1cc(C(=O)NC2CCCC2)c2ccccc2n1 nan
982830 45935 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.7 Cc1cc2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)n2c2ccccc12 nan
CHEMBL1532117 45935 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 4 1 5 4.7 Cc1cc2nnc(SCC(=O)Nc3ccc(F)c(Cl)c3)n2c2ccccc12 nan
895668 45951 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 4 3.2 CC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
CHEMBL1532290 45951 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 307 3 1 4 3.2 CC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
2078424 46017 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 2 4 2.9 COc1cccc(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 nan
CHEMBL1532835 46017 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 5 2 4 2.9 COc1cccc(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 nan
718477 46020 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 1 0 6 2.1 COc1nc(C)nc2c1sc(=S)n2C nan
CHEMBL1532843 46020 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 227 1 0 6 2.1 COc1nc(C)nc2c1sc(=S)n2C nan
3239288 46060 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 2.9 CCC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
CHEMBL1533246 46060 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 5 1 6 2.9 CCC(Sc1ccc2nnc(-c3ccc(F)cc3)n2n1)C(=O)O nan
16025355 46099 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 7 1 6 5.5 CCc1ccccc1NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(C)cc1)S2(=O)=O nan
CHEMBL1533601 46099 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 530 7 1 6 5.5 CCc1ccccc1NC(=O)CSc1ncc2c(n1)-c1ccccc1N(Cc1ccc(C)cc1)S2(=O)=O nan
3214708 46119 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 2 8 2.5 CC(=O)Nc1ccc(S(=O)(=O)N2CCN(Cc3nc(O)c4c(C)c(C)sc4n3)CC2)cc1 nan
CHEMBL1533736 46119 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 5 2 8 2.5 CC(=O)Nc1ccc(S(=O)(=O)N2CCN(Cc3nc(O)c4c(C)c(C)sc4n3)CC2)cc1 nan
16028279 46135 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 3.2 CCOc1ccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)cc1 nan
CHEMBL1533861 46135 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 448 8 1 8 3.2 CCOc1ccc(NC(=O)Cn2ccn3nc(-c4ccc(OC)c(OC)c4)cc3c2=O)cc1 nan
4046943 46152 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.5 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCC3)no1 nan
CHEMBL1534012 46152 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 4 1 6 2.5 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCC3)no1 nan
3932775 46168 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 3.8 CCc1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
CHEMBL1534252 46168 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 4 1 5 3.8 CCc1ccc2nc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)sc2c1 nan
4658600 46204 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 7 1 6 6.0 CCN(CC)C(=O)c1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
CHEMBL1534562 46204 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 506 7 1 6 6.0 CCN(CC)C(=O)c1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
16025630 46250 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 1 7 3.7 COc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
CHEMBL1535077 46250 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 5 1 7 3.7 COc1cccc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(C)S3(=O)=O)c1 nan
3185711 46263 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 9 3 8 2.6 CN(C)c1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2)cc1 nan
CHEMBL1535224 46263 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 522 9 3 8 2.6 CN(C)c1ccc(C(C(=O)NCC2CCCO2)N(C(=O)c2snc(C(N)=O)c2N)c2ccccc2)cc1 nan
54677757 46300 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 4 3.4 Cn1c(=O)c(Sc2ccccc2)c(O)c2ccccc21 nan
CHEMBL1535623 46300 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 1 4 3.4 Cn1c(=O)c(Sc2ccccc2)c(O)c2ccccc21 nan
4792884 46333 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 6 2.9 COc1ccc(Br)cc1-c1nc2c(c(=O)[nH]c(=O)n2Cc2ccccc2)n1C nan
CHEMBL1535940 46333 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 440 4 1 6 2.9 COc1ccc(Br)cc1-c1nc2c(c(=O)[nH]c(=O)n2Cc2ccccc2)n1C nan
135516269 46365 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 3.1 CCOc1ccc(-n2c(SCC(=O)NC(C)CC)nc3nnc(C)c-3c2N)cc1 nan
CHEMBL1536353 46365 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 8 2 8 3.1 CCOc1ccc(-n2c(SCC(=O)NC(C)CC)nc3nnc(C)c-3c2N)cc1 nan
3208311 46385 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 3 9 2.5 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cnc(O)nc1O)OCO3 nan
CHEMBL1536575 46385 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 3 9 2.5 CCc1cc2cc3c(cc2nc1SCC(=O)Nc1cnc(O)nc1O)OCO3 nan
1965061 46440 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 0 6 4.0 CCCCCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1Cc1ccc(OC)cc1 nan
CHEMBL1536987 46440 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 7 0 6 4.0 CCCCCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1Cc1ccc(OC)cc1 nan
2296181 46483 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 3 2.4 O=C(CNC(=S)NC(=O)C1CCCCC1)c1ccccc1 nan
CHEMBL1537419 46483 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 2 3 2.4 O=C(CNC(=S)NC(=O)C1CCCCC1)c1ccccc1 nan
4358102 46515 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.8 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1537648 46515 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 3.8 O=C(CCCCCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3)N1CCN(c2ccc(F)cc2)CC1 nan
16194098 46534 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 6 3.6 CSc1ccc(CNc2nc3ccccc3n3cnnc23)cc1 nan
CHEMBL1537791 46534 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 4 1 6 3.6 CSc1ccc(CNc2nc3ccccc3n3cnnc23)cc1 nan
1272394 46635 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 7 3.5 COc1ccc(C(=O)Nc2nnc(Cc3cccs3)s2)cc1OC nan
CHEMBL1538560 46635 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 361 6 1 7 3.5 COc1ccc(C(=O)Nc2nnc(Cc3cccs3)s2)cc1OC nan
921484 46731 13 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 4 4.1 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1 nan
CHEMBL1539494 46731 13 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 3 1 4 4.1 O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1 nan
664170 46802 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 0 8 3.5 CCOC(=O)N1CCN(c2nc(SC)nc3sc4c(c23)CC(C)(C)OC4)CC1 nan
CHEMBL1540011 46802 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 3 0 8 3.5 CCOC(=O)N1CCN(c2nc(SC)nc3sc4c(c23)CC(C)(C)OC4)CC1 nan
6621296 46885 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 6 3.3 O=C(NCc1ccccc1)C1CCCN(c2nc3ccsc3c(=O)s2)C1 nan
CHEMBL1540762 46885 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 385 4 1 6 3.3 O=C(NCc1ccccc1)C1CCCN(c2nc3ccsc3c(=O)s2)C1 nan
2855521 46951 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 2 4 3.2 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 nan
CHEMBL1541261 46951 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 2 4 3.2 COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 nan
687554 46979 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.1 CC(=O)Oc1ccc2oc(-c3ccccc3)c(C(N)=O)c2c1 nan
CHEMBL1541470 46979 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 295 3 1 4 3.1 CC(=O)Oc1ccc2oc(-c3ccccc3)c(C(N)=O)c2c1 nan
16746196 47159 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 10 3 5 3.2 CCCCNc1ccc(C(CC(N)=O)NC(=O)c2ccccc2)cc1[N+](=O)[O-] nan
CHEMBL1543039 47159 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 384 10 3 5 3.2 CCCCNc1ccc(C(CC(N)=O)NC(=O)c2ccccc2)cc1[N+](=O)[O-] nan
654907 47173 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 6 4.5 COc1ccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)cc1OC nan
CHEMBL1543164 47173 15 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 5 1 6 4.5 COc1ccc(C(=O)Nc2cccc(-c3nc4ncccc4o3)c2C)cc1OC nan
899145 47201 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 0 5 4.1 Cc1cnn(C(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)c1 nan
CHEMBL1543380 47201 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 0 5 4.1 Cc1cnn(C(=O)c2cc(-c3ccccn3)nc3ccc(Cl)cc23)c1 nan
1337412 47205 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
146674638 47205 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
CHEMBL1543421 47205 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 5 1 6 4.2 CCOc1ccc(-c2nn(-c3ccccc3)cc2/C=C2\SC(N)=NC2=O)cc1C nan
1773311 47250 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.1 CCN(CC)C(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
CHEMBL1543838 47250 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 7 3.1 CCN(CC)C(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N nan
22553577 47321 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 5 3.5 O=C(CCCn1c(=O)c2cccn2c2cccnc21)NCc1cccc(Br)c1 nan
CHEMBL1544274 47321 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 5 3.5 O=C(CCCn1c(=O)c2cccn2c2cccnc21)NCc1cccc(Br)c1 nan
2150501 47501 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 8 3.5 COCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2c(oc3ccccc32)c1=O nan
CHEMBL1545636 47501 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 8 1 8 3.5 COCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2c(oc3ccccc32)c1=O nan
1131000 47509 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.2 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2F)c1C nan
CHEMBL1545709 47509 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 4 2 5 3.2 COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2ccccc2F)c1C nan
4975679 47605 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 1 1 1 4.0 O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCc2ccccc2C1 nan
CHEMBL1546589 47605 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 1 1 1 4.0 O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCc2ccccc2C1 nan
4099286 47652 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 8 1 4 3.8 CCOc1ccc(CNC(=O)CCc2cn(C)c3ccccc23)cc1OC nan
CHEMBL1547036 47652 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 8 1 4 3.8 CCOc1ccc(CNC(=O)CCc2cn(C)c3ccccc23)cc1OC nan
246421 47661 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 3 6 3.0 CSc1nc(O)c(Nc2cccc(Cl)c2)c(O)n1 nan
CHEMBL1547116 47661 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 3 3 6 3.0 CSc1nc(O)c(Nc2cccc(Cl)c2)c(O)n1 nan
3179963 47771 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 3 7 2.3 CCC(C(=O)NC1CCCC1)N(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)cc1 nan
CHEMBL1548213 47771 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 8 3 7 2.3 CCC(C(=O)NC1CCCC1)N(C(=O)c1snc(C(N)=O)c1N)c1ccc(OC)cc1 nan
16608827 47790 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 5 3.8 COc1ccc(S(=O)(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1NC(C)=O nan
CHEMBL1548379 47790 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 7 1 5 3.8 COc1ccc(S(=O)(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1NC(C)=O nan
1711150 47898 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 8 1 6 3.6 COc1cc(/C=C/C(=O)OCC(=O)Nc2ccccc2Cl)cc(OC)c1OC nan
CHEMBL1549297 47898 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 8 1 6 3.6 COc1cc(/C=C/C(=O)OCC(=O)Nc2ccccc2Cl)cc(OC)c1OC nan
4371420 47903 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 0 4 2.9 O=C(COC(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1 nan
CHEMBL1549350 47903 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 5 0 4 2.9 O=C(COC(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1 nan
650104 48031 2 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 3.8 CCc1cc2ccc(OC)cc2nc1SCC(=O)Nc1cc(C)on1 nan
CHEMBL1550363 48031 2 None -3 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 3.8 CCc1cc2ccc(OC)cc2nc1SCC(=O)Nc1cc(C)on1 nan
891743 48076 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.5 Cc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)cs1 nan
CHEMBL1550704 48076 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 3 1 3 4.5 Cc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)cs1 nan
135437051 48121 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 3 6 4.1 CCc1ccccc1NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1cccc(C)c1 nan
CHEMBL1551159 48121 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 3 6 4.1 CCc1ccccc1NC(=O)CSc1nc2[nH]nc(C)c2c(=N)n1-c1cccc(C)c1 nan
16030615 48125 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 0 9 3.1 COc1ccc(C(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccccc5C)sc4n3)CC2)cc1OC nan
CHEMBL1551229 48125 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 6 0 9 3.1 COc1ccc(C(=O)N2CCN(Cc3cc(=O)n4nc(-c5ccccc5C)sc4n3)CC2)cc1OC nan
16018080 48128 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 6 3.5 COc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1OC nan
CHEMBL1551250 48128 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 1 6 3.5 COc1cccc(CNC(=O)CCCn2c(=O)c3cccn3c3ccc(F)cc32)c1OC nan
16012980 48137 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 3 5.3 Cc1ccc2nc(O)c(CN(C(=O)c3cccc(Cl)c3)C(C)(C)C)cc2c1 nan
CHEMBL1551350 48137 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 3 5.3 Cc1ccc2nc(O)c(CN(C(=O)c3cccc(Cl)c3)C(C)(C)C)cc2c1 nan
3534311 48144 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 6 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)COc3ccccc3)sc2c1 nan
CHEMBL1551511 48144 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 2 6 2.0 NS(=O)(=O)c1ccc2nc(NC(=O)COc3ccccc3)sc2c1 nan
16030318 48146 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.5 CCOc1ccc(C(=O)Nc2nnc(SCc3cc(=O)n4ccccc4n3)s2)cc1 nan
CHEMBL1551529 48146 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 9 3.5 CCOc1ccc(C(=O)Nc2nnc(SCc3cc(=O)n4ccccc4n3)s2)cc1 nan
16031341 48152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 2 1 5 1.9 Cc1ccccc1C(=O)Nc1nnc2n1CCS2 nan
CHEMBL1551637 48152 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 260 2 1 5 1.9 Cc1ccccc1C(=O)Nc1nnc2n1CCS2 nan
16012572 48156 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccc(Cl)cc3)c(C)nc21 nan
CHEMBL1551773 48156 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 5 1 5 4.4 Cc1cc(C)c2c(n1)nn1c(C)c(CCC(=O)NCc3ccc(Cl)cc3)c(C)nc21 nan
4112916 48170 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 0 5 5.2 CCOc1nc(-c2ccccc2)ccc1-c1noc(-c2ccc(C)cc2)n1 nan
CHEMBL1551932 48170 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 5 0 5 5.2 CCOc1nc(-c2ccccc2)ccc1-c1noc(-c2ccc(C)cc2)n1 nan
16030647 48172 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 6 0 8 3.6 CC(Oc1ccccc1)C(=O)N1CCN(Cc2cc(=O)n3nc(-c4ccccc4Cl)sc3n2)CC1 nan
CHEMBL1551961 48172 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 509 6 0 8 3.6 CC(Oc1ccccc1)C(=O)N1CCN(Cc2cc(=O)n3nc(-c4ccccc4Cl)sc3n2)CC1 nan
4069977 48180 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.3 CCOc1ccc(Sc2cc(C(=O)NC(C)c3ccccc3)c3ccccc3n2)cc1 nan
CHEMBL1552026 48180 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.3 CCOc1ccc(Sc2cc(C(=O)NC(C)c3ccccc3)c3ccccc3n2)cc1 nan
16027075 48188 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 0 8 4.8 COc1ccc(-c2nc(Cn3c(=O)cc(C)c4c(C)nn(-c5ccccc5)c43)c(C)o2)cc1OC nan
CHEMBL1552119 48188 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 6 0 8 4.8 COc1ccc(-c2nc(Cn3c(=O)cc(C)c4c(C)nn(-c5ccccc5)c43)c(C)o2)cc1OC nan
24792649 48192 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 0 0 3 3.5 Cn1c2ccccc2c(=O)c2ccc(C#Cc3ccccn3)cc21 nan
CHEMBL1552163 48192 0 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 0 0 3 3.5 Cn1c2ccccc2c(=O)c2ccc(C#Cc3ccccn3)cc21 nan
16020555 48214 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 0 5 4.8 O=c1c(S(=O)(=O)c2ccccc2)cn(Cc2cccc(F)c2)c2cc(N3CCCC3)c(F)cc12 nan
CHEMBL1552450 48214 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 480 5 0 5 4.8 O=c1c(S(=O)(=O)c2ccccc2)cn(Cc2cccc(F)c2)c2cc(N3CCCC3)c(F)cc12 nan
7217107 48217 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 2.4 Cc1ccc(NC(=O)c2cnc(SCC(=O)Nc3cc(C)on3)n(C)c2=O)cc1 nan
CHEMBL1552487 48217 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 6 2 8 2.4 Cc1ccc(NC(=O)c2cnc(SCC(=O)Nc3cc(C)on3)n(C)c2=O)cc1 nan
3666941 48218 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 6 1 6 4.9 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2-c2ccc(Br)cc2)cc1 nan
CHEMBL1552556 48218 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 499 6 1 6 4.9 Cc1ccc(CNC(=O)CSc2nc3ccsc3c(=O)n2-c2ccc(Br)cc2)cc1 nan
16010970 48231 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 0 7 3.6 CCc1cc2c(cc3c(=O)n(CC(=O)N4CCN(c5cc(Cl)ccc5C)CC4)ncn32)s1 nan
CHEMBL1552740 48231 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 4 0 7 3.6 CCc1cc2c(cc3c(=O)n(CC(=O)N4CCN(c5cc(Cl)ccc5C)CC4)ncn32)s1 nan
16021520 48234 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 4 4.6 CSc1ncc(C(=O)NCc2cccc(Br)c2)c(-c2ccccc2)n1 nan
CHEMBL1552765 48234 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 4 4.6 CSc1ncc(C(=O)NCc2cccc(Br)c2)c(-c2ccccc2)n1 nan
16024485 48253 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2n1 nan
CHEMBL1553018 48253 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 5 1 5 3.9 Cc1ccc2c(=O)c(C(=O)c3ccccc3)cn(CC(=O)Nc3ccccc3C)c2n1 nan
3160964 48257 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.6 Cc1cccc(OCC(=O)Nc2c(C)ccc3nsnc23)c1C nan
CHEMBL1553050 48257 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 4 1 5 3.6 Cc1cccc(OCC(=O)Nc2c(C)ccc3nsnc23)c1C nan
16012361 48305 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 5 4.2 CCc1ccccc1NC(=O)Cn1ncc2c(C)n(Cc3ccccc3F)c(C)c2c1=O nan
CHEMBL1553757 48305 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 6 1 5 4.2 CCc1ccccc1NC(=O)Cn1ncc2c(C)n(Cc3ccccc3F)c(C)c2c1=O nan
16027446 48321 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(OCc1cc(=O)n2nc(C3CC3)sc2n1)c1ccc(NC(=O)c2ccccc2F)cc1 nan
CHEMBL1553997 48321 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 8 3.8 O=C(OCc1cc(=O)n2nc(C3CC3)sc2n1)c1ccc(NC(=O)c2ccccc2F)cc1 nan
16030862 48348 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 3 3.1 CC(=O)N1CCc2cc(CNS(=O)(=O)c3ccccc3C(F)(F)F)ccc21 nan
CHEMBL1554375 48348 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 4 1 3 3.1 CC(=O)N1CCc2cc(CNS(=O)(=O)c3ccccc3C(F)(F)F)ccc21 nan
16030106 48357 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1ccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)cc1 nan
CHEMBL1554505 48357 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 6 1 7 3.2 COc1ccc(CNC(=O)Cn2nc(C)c3nn(-c4ccc(Cl)cc4)c(C)c3c2=O)cc1 nan
4074992 48363 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.9 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(F)cc3)c3ccccc3n2)cc1 nan
CHEMBL1554644 48363 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 1 4 5.9 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(F)cc3)c3ccccc3n2)cc1 nan
5058559 48375 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 2.9 CC(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)OC(C)C3)cc2)c1 nan
CHEMBL1554762 48375 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 2.9 CC(=O)c1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)OC(C)C3)cc2)c1 nan
16026882 48376 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 8 3.5 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1554822 48376 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 417 6 0 8 3.5 O=C(COc1ccc(F)cc1)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
4289361 48390 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1cccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)c1 nan
CHEMBL1555049 48390 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 7 1 5 5.3 CCOc1cccc(C(=O)Nc2c(C(=O)c3ccc(OC)cc3)oc3ccccc23)c1 nan
3282564 48397 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.6 Cc1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)s2)cc1 nan
CHEMBL1555127 48397 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 347 3 1 4 4.6 Cc1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)s2)cc1 nan
16009325 48408 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 7 3.2 O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
CHEMBL1555288 48408 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 5 1 7 3.2 O=C(Cn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc3c(cc21)OCO3)Nc1ccccc1 nan
135416425 48411 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 2 4 5.1 Cc1ccccc1C(=O)Nc1cc(C)c(O)c(-c2nc3ccccc3o2)c1 nan
CHEMBL1555312 48411 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 358 3 2 4 5.1 Cc1ccccc1C(=O)Nc1cc(C)c(O)c(-c2nc3ccccc3o2)c1 nan
16023840 48461 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 6 4.3 CCOC(=O)c1c(C)oc2nc(C)nc(NCc3ccccc3Cl)c12 nan
CHEMBL1555863 48461 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 5 1 6 4.3 CCOC(=O)c1c(C)oc2nc(C)nc(NCc3ccccc3Cl)c12 nan
4432211 48470 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 6 2.5 CC(=O)N1CCc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C#N)C1 nan
CHEMBL1555967 48470 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 383 2 1 6 2.5 CC(=O)N1CCc2c(sc(NC(=O)c3ccc4c(c3)OCCO4)c2C#N)C1 nan
929959 48505 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 8 0.8 COc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
CHEMBL1556274 48505 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 2 1 8 0.8 COc1ccc(-c2c(C#N)c(N)nc3c2c(=O)n(C)c(=O)n3C)cc1 nan
1718133 48533 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 5 4.3 CCCCCC(=O)NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1 nan
CHEMBL1556586 48533 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 6 2 5 4.3 CCCCCC(=O)NC(=S)Nc1cccc(-c2nc3ncccc3o2)c1 nan
1475314 48544 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 251 2 1 4 3.2 Cc1nc(N)ncc1Sc1ccc(Cl)cc1 nan
CHEMBL1556672 48544 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 251 2 1 4 3.2 Cc1nc(N)ncc1Sc1ccc(Cl)cc1 nan
1829088 48596 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 5 2.5 COCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O nan
CHEMBL1557090 48596 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 6 1 5 2.5 COCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O nan
16008924 48606 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 3 1 4 3.6 Cn1c(C(=O)NCc2ccc(Cl)cc2)cc2c(=O)n(C)c3ccccc3c21 nan
CHEMBL1557189 48606 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 379 3 1 4 3.6 Cn1c(C(=O)NCc2ccc(Cl)cc2)cc2c(=O)n(C)c3ccccc3c21 nan
20868637 48649 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 3.8 CCOc1ccc2ncc(S(=O)(=O)c3ccc(C)c(C)c3)c(O)c2c1 nan
CHEMBL1557551 48649 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 4 1 5 3.8 CCOc1ccc2ncc(S(=O)(=O)c3ccc(C)c(C)c3)c(O)c2c1 nan
16030924 48665 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 6 5.1 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccc(C)c(Cl)c4)ccc3n2)cc1 nan
CHEMBL1557656 48665 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 438 6 1 6 5.1 COc1ccc(-c2cn3nc(SCC(=O)Nc4ccc(C)c(Cl)c4)ccc3n2)cc1 nan
899391 48670 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 2.8 O=C(Cc1ccccc1)Nc1nc(=O)c2ccccc2s1 nan
CHEMBL1557721 48670 12 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 1 4 2.8 O=C(Cc1ccccc1)Nc1nc(=O)c2ccccc2s1 nan
3846782 48672 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 4 1 7 4.1 Cc1ccc(Cn2c(=N)c(S(=O)(=O)c3ccc(Br)cc3)cc3c(=O)n4ccccc4nc32)cc1 nan
CHEMBL1557740 48672 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 4 1 7 4.1 Cc1ccc(Cn2c(=N)c(S(=O)(=O)c3ccc(Br)cc3)cc3c(=O)n4ccccc4nc32)cc1 nan
1485561 48694 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 3 0 5 4.4 O=S(=O)(c1ccccc1)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 nan
CHEMBL1557929 48694 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 3 0 5 4.4 O=S(=O)(c1ccccc1)c1cnn2c(C(F)(F)F)cc(-c3ccc(F)cc3)nc12 nan
54706216 48750 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 3 4 3.5 O=C(NC1CCCCCCC1)c1c(O)nc2ccccc2c1O nan
CHEMBL1558469 48750 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 314 2 3 4 3.5 O=C(NC1CCCCCCC1)c1c(O)nc2ccccc2c1O nan
5185520 48761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 2 4 2.5 Nc1cc(Cl)ccc1C(=O)OCC(=O)NC1CCCCC1 nan
CHEMBL1558534 48761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 310 4 2 4 2.5 Nc1cc(Cl)ccc1C(=O)OCC(=O)NC1CCCCC1 nan
666603 48795 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 6 4.1 Cc1nn(-c2ccc(F)cc2)c2nc(N)c(C#N)c(-c3cccs3)c12 nan
CHEMBL1558784 48795 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 2 1 6 4.1 Cc1nn(-c2ccc(F)cc2)c2nc(N)c(C#N)c(-c3cccs3)c12 nan
15991438 48803 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 6 3.8 Cc1cccc(NC(=O)CSc2nc3ccccc3nc2N2CCOCC2)c1C nan
CHEMBL1558859 48803 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 5 1 6 3.8 Cc1cccc(NC(=O)CSc2nc3ccccc3nc2N2CCOCC2)c1C nan
950988 48819 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 2 5 4.8 COc1cccc(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
CHEMBL1558977 48819 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 2 5 4.8 COc1cccc(Nc2nc(-c3ccccc3O)nc3ccccc23)c1 nan
4345257 48830 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 2 6 3.2 Cc1cc(C)cc(NC(=O)CSc2nnc(NC(=O)C3CC3)s2)c1 nan
CHEMBL1559060 48830 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 2 6 3.2 Cc1cc(C)cc(NC(=O)CSc2nnc(NC(=O)C3CC3)s2)c1 nan
900716 48842 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 5 3.6 COC(=O)c1ccc(NC(=O)c2ccc3nc(C)sc3c2)cc1 nan
CHEMBL1559158 48842 19 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 3 1 5 3.6 COC(=O)c1ccc(NC(=O)c2ccc3nc(C)sc3c2)cc1 nan
2156049 48912 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 4 5.5 Cc1ccc(-n2c(SCc3ccccc3)nc3c([nH]c4ccccc43)c2=O)cc1 nan
CHEMBL1559857 48912 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 4 1 4 5.5 Cc1ccc(-n2c(SCc3ccccc3)nc3c([nH]c4ccccc43)c2=O)cc1 nan
3138574 48915 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 3 4 3.6 O=C(NNc1c2ccccc2nc2ccccc12)C(O)c1ccccc1 nan
CHEMBL1559872 48915 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 3 4 3.6 O=C(NNc1c2ccccc2nc2ccccc12)C(O)c1ccccc1 nan
16017814 48934 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 6 2.9 COc1ccc(Cl)cc1NC(=O)Cn1ccn(-c2cc(C)cc(C)c2)c(=O)c1=O nan
CHEMBL1560031 48934 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 5 1 6 2.9 COc1ccc(Cl)cc1NC(=O)Cn1ccn(-c2cc(C)cc(C)c2)c(=O)c1=O nan
2028031 49008 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 1 0 5 3.5 Cc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1C1CCCCCC1 nan
CHEMBL1560823 49008 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 1 0 5 3.5 Cc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1C1CCCCCC1 nan
4690835 49011 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 COc1ccc2oc(-c3cccc(NC(=O)c4ccc(C#N)cc4F)c3)nc2c1 nan
CHEMBL1560860 49011 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 387 4 1 5 4.8 COc1ccc2oc(-c3cccc(NC(=O)c4ccc(C#N)cc4F)c3)nc2c1 nan
15990056 49183 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 5 4.4 CCc1nnc2c3ccccc3nc(Nc3ccc(F)c(Cl)c3)n12 nan
CHEMBL1562390 49183 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 1 5 4.4 CCc1nnc2c3ccccc3nc(Nc3ccc(F)c(Cl)c3)n12 nan
5299641 49187 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 4.6 Cc1ccc(Cl)cc1NC(=O)CSc1nc(C)c(C)c(C)c1C#N nan
CHEMBL1562426 49187 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 4 1 4 4.6 Cc1ccc(Cl)cc1NC(=O)CSc1nc(C)c(C)c(C)c1C#N nan
135496880 49190 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 9 3.5 Oc1nc(SCc2nc(O)c3cnn(-c4ccccc4)c3n2)nc2ccccc12 nan
CHEMBL1562459 49190 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 4 2 9 3.5 Oc1nc(SCc2nc(O)c3cnn(-c4ccccc4)c3n2)nc2ccccc12 nan
1176245 49236 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 4.0 CCOc1ccc2nc(SCC(=O)Nc3cc(C)on3)c(C)cc2c1 nan
CHEMBL1562840 49236 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 6 1 6 4.0 CCOc1ccc2nc(SCC(=O)Nc3cc(C)on3)c(C)cc2c1 nan
16030293 49239 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 5 6.0 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)Nc1ccccc1C(F)(F)F nan
CHEMBL1562857 49239 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 7 1 5 6.0 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)Nc1ccccc1C(F)(F)F nan
16008836 49318 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.2 O=C(NCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2c(Cl)nc3ccccc3c2s1 nan
CHEMBL1563658 49318 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 6 1 5 5.2 O=C(NCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2c(Cl)nc3ccccc3c2s1 nan
258436 49388 46 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 1 0 2 2.5 CN1C=CC(=CC=C2C=CC(=O)C=C2)C=C1 nan
CHEMBL1564141 49388 46 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 1 0 2 2.5 CN1C=CC(=CC=C2C=CC(=O)C=C2)C=C1 nan
16030542 49407 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2cccc(OCc3cc(=O)n4ccccc4n3)c2)cc1C nan
CHEMBL1564400 49407 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 7 1 6 3.9 Cc1ccc(OCC(=O)Nc2cccc(OCc3cc(=O)n4ccccc4n3)c2)cc1C nan
2819137 49467 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 1 6 2.3 COc1cccc(-c2nc(N)nc(SC)c2C#N)c1 nan
CHEMBL1564918 49467 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 272 3 1 6 2.3 COc1cccc(-c2nc(N)nc(SC)c2C#N)c1 nan
3244591 49471 1 None -100 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 6 4.3 CC(C)CCn1c(SCC#N)nc2c(sc3ccccc32)c1=O nan
CHEMBL1564940 49471 1 None -100 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 5 0 6 4.3 CC(C)CCn1c(SCC#N)nc2c(sc3ccccc32)c1=O nan
16010206 49483 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
CHEMBL1565063 49483 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 470 5 1 7 1.6 CCc1ccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc3c(c2)n(C)c(=O)c(=O)n3C)cc1 nan
1147655 49486 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 7 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1OC nan
CHEMBL1565079 49486 20 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 392 5 1 7 3.0 COc1ccc(C(=O)Nc2nc3ccc(S(C)(=O)=O)cc3s2)cc1OC nan
694360 49535 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 5 3.1 N#Cc1c(-c2cccs2)cc(C2CC2)nc1SCC(N)=O nan
CHEMBL1565417 49535 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 315 5 1 5 3.1 N#Cc1c(-c2cccs2)cc(C2CC2)nc1SCC(N)=O nan
16021091 49579 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3cccnc32)cc1 nan
CHEMBL1565772 49579 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 486 8 1 6 5.8 COc1ccc(Cn2c(SCc3ccc(C(=O)NC4CCCCC4)cc3)nc3cccnc32)cc1 nan
16019049 49665 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 7 3.6 COc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c(OC)c1 nan
CHEMBL1566421 49665 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 7 1 7 3.6 COc1ccc(CNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)c(OC)c1 nan
2810064 49673 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 7 2.5 COc1cc2nc(NC(=O)c3ccco3)sc(=O)c2cc1OC nan
CHEMBL1566488 49673 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 4 1 7 2.5 COc1cc2nc(NC(=O)c3ccco3)sc(=O)c2cc1OC nan
15988926 49827 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 12 1 7 3.0 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
CHEMBL1567696 49827 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 12 1 7 3.0 CCN(CC)C(=O)Cn1c(=O)n(CCCCCC(=O)NCc2ccccc2)c(=O)c2sccc21 nan
16017081 49917 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 4.5 CCC(C(=O)Nc1ccccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1568421 49917 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 5 1 6 4.5 CCC(C(=O)Nc1ccccc1OC)n1nc(C)c2sc3ccccc3c2c1=O nan
16030322 49968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 8 2.9 CCCC(=O)Nc1nnc(SCc2cc(=O)n3cccc(C)c3n2)s1 nan
CHEMBL1568901 49968 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 6 1 8 2.9 CCCC(=O)Nc1nnc(SCc2cc(=O)n3cccc(C)c3n2)s1 nan
713644 49984 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 5 1.4 Cc1cn(C(=O)CN2C(=O)c3ccccc3C2=O)c(C)n1 nan
CHEMBL1569010 49984 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 5 1.4 Cc1cn(C(=O)CN2C(=O)c3ccccc3C2=O)c(C)n1 nan
16024577 50023 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 3.7 COc1cc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc(OC)c1 nan
CHEMBL1569365 50023 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 7 3.7 COc1cc(NC(=O)Cn2cc(C(=O)c3ccc(F)cc3)c(=O)c3ccc(C)nc32)cc(OC)c1 nan
1146106 50047 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 5 5.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(Cl)cc3)n2)cc1 nan
CHEMBL1569521 50047 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 467 7 1 5 5.2 COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)NCc3ccc(Cl)cc3)n2)cc1 nan
1433832 50069 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 4 1 4 2.5 N#Cc1cc2ccccc2nc1SCC(=O)NC1CC1 nan
CHEMBL1569775 50069 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 4 1 4 2.5 N#Cc1cc2ccccc2nc1SCC(=O)NC1CC1 nan
660750 50073 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.9 Cn1nnnc1-c1cc(Br)ccc1NC(=O)c1ccccc1 nan
CHEMBL1569814 50073 8 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 357 3 1 5 2.9 Cn1nnnc1-c1cc(Br)ccc1NC(=O)c1ccccc1 nan
16020020 50132 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 5 0 5 4.2 CCOC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)cc2)c1C nan
CHEMBL1570342 50132 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 351 5 0 5 4.2 CCOC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)cc2)c1C nan
893344 50133 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 3.3 Cn1nnc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 nan
CHEMBL1570344 50133 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 2 2 4 3.3 Cn1nnc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 nan
7692920 50200 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 3.0 O=C(Nc1nnc(S(=O)(=O)Cc2ccc(F)cc2)s1)c1ccccc1F nan
CHEMBL1570825 50200 13 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 1 6 3.0 O=C(Nc1nnc(S(=O)(=O)Cc2ccc(F)cc2)s1)c1ccccc1F nan
16015598 50264 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 6.0 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccccc3)on2)cc1 nan
CHEMBL1571539 50264 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 7 1 6 6.0 CCOc1ccc(C(=O)c2oc3ccccc3c2NC(=O)c2cc(-c3ccccc3)on2)cc1 nan
16015076 50328 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 6 4.0 COC(=O)c1ccccc1NC(=O)CSc1cc(-c2ccccc2)nc(C)n1 nan
CHEMBL1572102 50328 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 6 1 6 4.0 COC(=O)c1ccccc1NC(=O)CSc1cc(-c2ccccc2)nc(C)n1 nan
663126 50390 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 6 5.1 Clc1ccc(OCc2nn3c(C4CCCCC4)nnc3s2)c(Cl)c1 nan
CHEMBL1572687 50390 9 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 4 0 6 5.1 Clc1ccc(OCc2nn3c(C4CCCCC4)nnc3s2)c(Cl)c1 nan
2318048 50414 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 7 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1OC nan
CHEMBL1572874 50414 14 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 7 3.7 COc1ccc(-c2csc(NC(=O)c3ccc(N4C(=O)CCC4=O)cc3)n2)cc1OC nan
135492018 50436 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135635832 50436 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135914561 50436 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
CHEMBL1573000 50436 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 3 1 4 3.4 O=C1N=C(Nc2ccccn2)SC1Cc1ccccc1Cl nan
135870946 50460 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 8 1.6 COc1ccc(C(=O)COC(=O)CCNC2=NS(=O)(=O)c3ccccc32)c(OC)c1 nan
CHEMBL1573236 50460 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 8 1 8 1.6 COc1ccc(C(=O)COC(=O)CCNC2=NS(=O)(=O)c3ccccc32)c(OC)c1 nan
16011872 50464 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 0 6 7.1 Cc1cccc(-c2nc(Cn3c(SCc4cccc(C(F)(F)F)c4)nc4ccncc43)c(C)o2)c1 nan
CHEMBL1573276 50464 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 6 0 6 7.1 Cc1cccc(-c2nc(Cn3c(SCc4cccc(C(F)(F)F)c4)nc4ccncc43)c(C)o2)c1 nan
16019020 50477 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
CHEMBL1573442 50477 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 6 1 5 4.0 Cc1ccc(CCNC(=O)c2ccc(Cn3c(=O)c4cccn4c4cccnc43)cc2)cc1 nan
4599423 50523 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 3 1 5.2 S=C(NCc1ccc2[nH]c3c(c2c1)CCCC3)Nc1ccccc1Cl nan
CHEMBL1573942 50523 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 3 3 1 5.2 S=C(NCc1ccc2[nH]c3c(c2c1)CCCC3)Nc1ccccc1Cl nan
16014814 50566 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.2 Cc1cccc(NC(=O)c2c(C)cc(C)nc2SCC(=O)c2ccccc2)c1 nan
CHEMBL1574276 50566 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 5.2 Cc1cccc(NC(=O)c2c(C)cc(C)nc2SCC(=O)c2ccccc2)c1 nan
921918 50684 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 0 5 4.8 Fc1ccc(-n2c(-c3cccs3)nc3nc4ccccc4nc32)cc1 nan
CHEMBL1575663 50684 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 2 0 5 4.8 Fc1ccc(-n2c(-c3cccs3)nc3nc4ccccc4nc32)cc1 nan
1960193 50739 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 4 3.9 Cn1c(NC(=O)c2ccccc2)c(-c2ccccn2)c(=O)c2ccccc21 nan
CHEMBL1576207 50739 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 4 3.9 Cn1c(NC(=O)c2ccccc2)c(-c2ccccn2)c(=O)c2ccccc21 nan
5846704 50748 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 9 1 5 3.9 CCN(CC)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
CHEMBL1576280 50748 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 9 1 5 3.9 CCN(CC)CCCNc1oc(/C=C/c2ccccc2)nc1C#N nan
935443 50758 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 2 5.1 Cc1ccc(NC(S)=Nc2cc(-c3ccccc3)[nH]n2)cc1Cl nan
CHEMBL1576343 50758 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 342 3 3 2 5.1 Cc1ccc(NC(S)=Nc2cc(-c3ccccc3)[nH]n2)cc1Cl nan
3228917 50827 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 5 4.7 CCc1cccc(C)c1NC(=O)CSc1[nH]c(-c2ccccc2F)nc2ncnc1-2 nan
CHEMBL1576889 50827 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 2 5 4.7 CCc1cccc(C)c1NC(=O)CSc1[nH]c(-c2ccccc2F)nc2ncnc1-2 nan
709545 50863 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 2.9 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)no1 nan
CHEMBL1577228 50863 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 1 6 2.9 Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCC3)no1 nan
3917007 50971 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 2.9 O=C1COc2ccc(C(=O)COC(=O)CCSc3ccccc3)cc2N1 nan
CHEMBL1578153 50971 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 371 7 1 6 2.9 O=C1COc2ccc(C(=O)COC(=O)CCSc3ccccc3)cc2N1 nan
20884721 51158 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.7 COc1cccc2c1cc1c(=O)n(CC(=O)NCc3ccccn3)nc(C)n12 nan
CHEMBL1579740 51158 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 5 1 7 1.7 COc1cccc2c1cc1c(=O)n(CC(=O)NCc3ccccn3)nc(C)n12 nan
1292507 51203 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 7 4.4 Cc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3sc(C)c(C)c3c2=O)cc1 nan
CHEMBL1580140 51203 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 6 1 7 4.4 Cc1ccc(-n2c(SCC(=O)NCc3ccco3)nc3sc(C)c(C)c3c2=O)cc1 nan
2347564 51424 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 9 1.6 Cc1nn(-c2ccccc2)c2sc(C(=O)c3c(N)n(C)c(=O)n(C)c3=O)cc12 nan
CHEMBL1581991 51424 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 3 1 9 1.6 Cc1nn(-c2ccccc2)c2sc(C(=O)c3c(N)n(C)c(=O)n(C)c3=O)cc12 nan
1454917 51454 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1cccc(C)c1)C1CC1)c1nnnn12 nan
CHEMBL1582197 51454 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 5 1 5 4.7 CCc1ccc2c(c1)cc(CN(C(S)=Nc1cccc(C)c1)C1CC1)c1nnnn12 nan
7080789 51520 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 3 4 3.3 Cc1ccc2cc(CCNC(=O)C(=O)c3c[nH]c4ccccc34)c(O)nc2c1 nan
CHEMBL1582792 51520 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 3 4 3.3 Cc1ccc2cc(CCNC(=O)C(=O)c3c[nH]c4ccccc34)c(O)nc2c1 nan
1420394 51539 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 4 5.2 Cc1ccc2cc(CN(C(=O)c3cccs3)c3ccccc3)c(O)nc2c1 nan
CHEMBL1583002 51539 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 4 1 4 5.2 Cc1ccc2cc(CN(C(=O)c3cccs3)c3ccccc3)c(O)nc2c1 nan
2012958 51586 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 4.1 Cc1nc(SCC(=O)NCc2ccccc2)c2oc3ccccc3c2n1 nan
CHEMBL1583344 51586 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 363 5 1 5 4.1 Cc1nc(SCC(=O)NCc2ccccc2)c2oc3ccccc3c2n1 nan
2810452 51612 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 0 6 3.5 Cc1cc(C)c(-n2nnnc2SC2Cc3ccccc3C2=O)c(C)c1 nan
CHEMBL1583573 51612 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 350 3 0 6 3.5 Cc1cc(C)c(-n2nnnc2SC2Cc3ccccc3C2=O)c(C)c1 nan
4102688 51699 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 5 2.6 Cc1cccc(NC(=O)c2cnc3sccn3c2=O)c1C nan
CHEMBL1584232 51699 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 299 2 1 5 2.6 Cc1cccc(NC(=O)c2cnc3sccn3c2=O)c1C nan
15944711 51702 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 5 3.9 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccccc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1584268 51702 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 5 1 5 3.9 Cc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccccc3)c(=O)c3cc(F)ccc32)cc1 nan
2981373 51952 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 4 4.3 Cc1nc(Nc2cccc(C(F)(F)F)c2)nc2c1C(=O)CC(C)C2 nan
CHEMBL1586327 51952 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 2 1 4 4.3 Cc1nc(Nc2cccc(C(F)(F)F)c2)nc2c1C(=O)CC(C)C2 nan
6404569 52093 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 0 3 5.4 c1ccc(Cc2nnc(Sc3ccccc3)c3ccccc23)cc1 nan
CHEMBL1587518 52093 15 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 328 4 0 3 5.4 c1ccc(Cc2nnc(Sc3ccccc3)c3ccccc23)cc1 nan
16189382 52245 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1cccc(N(C)C(=O)c2cc3c(O)nc4ccc(C)cc4c3s2)c1 nan
CHEMBL1588813 52245 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 4 5.0 Cc1cccc(N(C)C(=O)c2cc3c(O)nc4ccc(C)cc4c3s2)c1 nan
5770860 52287 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 2 6 2.4 CCOC(=O)CNC(=O)c1sc(NC(=O)/C=C/c2ccccc2)nc1C nan
CHEMBL1589172 52287 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 7 2 6 2.4 CCOC(=O)CNC(=O)c1sc(NC(=O)/C=C/c2ccccc2)nc1C nan
2428876 52290 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 4 2.7 O=C(COc1ccc2ccccc2c1)Nc1cccc2c1C(=O)NC2=O nan
CHEMBL1589183 52290 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 346 4 2 4 2.7 O=C(COc1ccc2ccccc2c1)Nc1cccc2c1C(=O)NC2=O nan
16007870 52373 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 8 1 4 4.9 Cc1ccc(CCNC(=O)CSCc2nc(-c3ccc(C)cc3)oc2C)cc1 nan
CHEMBL1589908 52373 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 394 8 1 4 4.9 Cc1ccc(CCNC(=O)CSCc2nc(-c3ccc(C)cc3)oc2C)cc1 nan
6418319 52390 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 5.7 O=C(CSc1nnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1)NC1CCCC1 nan
CHEMBL1590097 52390 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 5 5.7 O=C(CSc1nnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1)NC1CCCC1 nan
16025990 52401 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 2.2 Cc1c(Cl)cccc1NC(=O)c1cnc2sc(N3CCOCC3)nn2c1=O nan
CHEMBL1590252 52401 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 405 3 1 8 2.2 Cc1c(Cl)cccc1NC(=O)c1cnc2sc(N3CCOCC3)nn2c1=O nan
16030611 52418 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCc3ccccc32)c1 nan
CHEMBL1590504 52418 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 0 5 5.3 COc1cccc(Cc2nc3ccccc3nc2SCC(=O)N2CCCc3ccccc32)c1 nan
16009482 52419 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 7 3.9 COc1ccccc1C(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
CHEMBL1590536 52419 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 6 1 7 3.9 COc1ccccc1C(=O)Nc1ccccc1OCc1cc(=O)n2c(C)csc2n1 nan
16015095 52420 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 6 5.5 CCOc1ccccc1NC(=O)c1sc(-n2nc(C)c(CCC(C)C)c2C)nc1C nan
CHEMBL1590548 52420 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 8 1 6 5.5 CCOc1ccccc1NC(=O)c1sc(-n2nc(C)c(CCC(C)C)c2C)nc1C nan
16019575 52428 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 5 1 9 4.6 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
CHEMBL1590659 52428 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 505 5 1 9 4.6 O=S(=O)(c1ccc(Br)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 nan
4249793 52435 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 2 4 1.8 COc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)NC2=O nan
CHEMBL1590747 52435 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 3 2 4 1.8 COc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)NC2=O nan
16016850 52443 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 2 3 5.9 COc1ccc2c(Sc3ccccc3)c(C(=O)NCC(C)c3ccccc3)[nH]c2c1 nan
CHEMBL1590842 52443 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 2 3 5.9 COc1ccc2c(Sc3ccccc3)c(C(=O)NCC(C)c3ccccc3)[nH]c2c1 nan
16025801 52477 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 1 7 2.9 COc1cccc(CNc2nccn(-c3ccc(OC)c(OC)c3)c2=O)c1 nan
CHEMBL1591265 52477 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 7 1 7 2.9 COc1cccc(CNc2nccn(-c3ccc(OC)c(OC)c3)c2=O)c1 nan
7533419 52517 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 8 1 6 3.5 CCOc1ccc(-c2nnc(SCC(=O)NCc3ccccc3)o2)cc1 nan
CHEMBL1591699 52517 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 369 8 1 6 3.5 CCOc1ccc(-c2nnc(SCC(=O)NCc3ccccc3)o2)cc1 nan
16030248 52538 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 5 3.7 O=C(CSc1nnc(-c2ccccc2Cl)[nH]1)N1CCN(c2ccc(F)cc2)CC1 nan
CHEMBL1591982 52538 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 5 3.7 O=C(CSc1nnc(-c2ccccc2Cl)[nH]1)N1CCN(c2ccc(F)cc2)CC1 nan
16021788 52548 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 3.3 O=C(NCc1ccccc1)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
CHEMBL1592133 52548 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 5 2 7 3.3 O=C(NCc1ccccc1)c1cccc(Nc2nc3ccccc3n3nnnc23)c1 nan
16008534 52587 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.2 CCOC(=O)C(Cc1ccccc1)NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)c(C)c2)c1C nan
CHEMBL1592680 52587 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 512 9 1 6 5.2 CCOC(=O)C(Cc1ccccc1)NC(=O)CCc1c(C)nc2c(c(C)nn2-c2ccc(C)c(C)c2)c1C nan
16012042 52589 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 5 4.6 O=C(Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O)NCCc1ccc(Cl)cc1 nan
CHEMBL1592702 52589 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 7 1 5 4.6 O=C(Cn1ncc2c3ccccc3n(Cc3ccccc3F)c2c1=O)NCCc1ccc(Cl)cc1 nan
15991036 52602 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 6.7 COc1ccc(Cl)cc1C(=O)Nc1ccc2oc(-c3ccc(C(C)(C)C)cc3)nc2c1 nan
CHEMBL1592855 52602 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 4 6.7 COc1ccc(Cl)cc1C(=O)Nc1ccc2oc(-c3ccc(C(C)(C)C)cc3)nc2c1 nan
16026106 52617 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 5 3.9 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccco2)CC1 nan
CHEMBL1593080 52617 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 5 3.9 CC1=C(c2ccc(C(C)C)cc2)S(=O)(=O)N=C1N1CCC(C(=O)NCc2ccco2)CC1 nan
16009361 52620 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 1 6 4.3 CCOc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
CHEMBL1593099 52620 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 494 7 1 6 4.3 CCOc1ccc(NC(=O)Cn2cc(S(=O)(=O)c3ccc(C)cc3)c(=O)c3cc(F)ccc32)cc1 nan
16030919 52625 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.7 CCc1ccc(NC(=O)CSc2ccc3nc(-c4ccc(OC)cc4)cn3n2)cc1 nan
CHEMBL1593184 52625 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 7 1 6 4.7 CCc1ccc(NC(=O)CSc2ccc3nc(-c4ccc(OC)cc4)cn3n2)cc1 nan
16033356 52630 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.5 COc1ccc(CC(=O)Nc2ccc(-c3nc4ccccc4s3)c(C)c2)cc1 nan
CHEMBL1593249 52630 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 4 5.5 COc1ccc(CC(=O)Nc2ccc(-c3nc4ccccc4s3)c(C)c2)cc1 nan
16015767 52659 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 0 5 3.9 Cc1ccc(CN(C(=O)COc2ccccc2[N+](=O)[O-])c2ccccn2)cc1 nan
CHEMBL1593732 52659 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 7 0 5 3.9 Cc1ccc(CN(C(=O)COc2ccccc2[N+](=O)[O-])c2ccccn2)cc1 nan
15990880 52664 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 3 5.6 Cc1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)c(C)c1 nan
CHEMBL1593807 52664 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 395 6 2 3 5.6 Cc1ccc(Nc2cc(C(=O)NCCc3ccccc3)c3ccccc3n2)c(C)c1 nan
3623411 52676 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.0 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(C)cc3)c3ccccc3n2)cc1 nan
CHEMBL1593971 52676 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 7 1 4 6.0 CCOc1ccc(Sc2cc(C(=O)NCc3ccc(C)cc3)c3ccccc3n2)cc1 nan
16030473 52747 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n2c1 nan
CHEMBL1594609 52747 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 5 1 5 4.5 Cc1ccc2nc(COc3cccc(NC(=O)c4cccc(Cl)c4)c3)cc(=O)n2c1 nan
2328630 52761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 6 1 6 2.9 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nccc(C)n2)c1C nan
CHEMBL1594696 52761 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 6 1 6 2.9 CCOC(=O)c1c(C)[nH]c(C(=O)CSc2nccc(C)n2)c1C nan
16027342 52815 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.1 Cc1cc(=O)n(Cc2cccc(F)c2)c2c1c(C)nn2-c1cccc(F)c1 nan
CHEMBL1595156 52815 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 365 3 0 4 4.1 Cc1cc(=O)n(Cc2cccc(F)c2)c2c1c(C)nn2-c1cccc(F)c1 nan
16021494 52822 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 4 3.9 CSc1ncc(C(=O)NCc2ccc(F)cc2)c(-c2ccccc2)n1 nan
CHEMBL1595189 52822 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 4 3.9 CSc1ncc(C(=O)NCc2ccc(F)cc2)c(-c2ccccc2)n1 nan
4584398 52924 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 1 2 4.7 Cn1c(C(=O)Nc2ccc(Cl)cc2)cc2cc(Cl)ccc21 nan
CHEMBL1596148 52924 8 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 318 2 1 2 4.7 Cn1c(C(=O)Nc2ccc(Cl)cc2)cc2cc(Cl)ccc21 nan
16016964 52956 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.7 Cc1cc(C)c2c(-n3cccc3)c(C(=O)NCCc3ccccc3)sc2n1 nan
CHEMBL1596415 52956 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 5 1 4 4.7 Cc1cc(C)c2c(-n3cccc3)c(C(=O)NCCc3ccccc3)sc2n1 nan
891582 52981 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 0 5 3.8 Cc1cccc(-n2ncc3c(N4CCc5ccccc54)ncnc32)c1 nan
CHEMBL1596656 52981 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 327 2 0 5 3.8 Cc1cccc(-n2ncc3c(N4CCc5ccccc54)ncnc32)c1 nan
2138637 52984 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 2 6 3.5 CC(=O)NCCNc1nc2c(-c3cccc(C(F)(F)F)c3)nnn2c2ccccc12 nan
CHEMBL1596664 52984 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 414 5 2 6 3.5 CC(=O)NCCNc1nc2c(-c3cccc(C(F)(F)F)c3)nnn2c2ccccc12 nan
4062063 53050 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 3 8 -0.4 CN(CCO)S(=O)(=O)c1ccc2c(c1)C(=NN)c1cc(S(=O)(=O)N(C)CCO)ccc1-2 nan
CHEMBL1597275 53050 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 8 3 8 -0.4 CN(CCO)S(=O)(=O)c1ccc2c(c1)C(=NN)c1cc(S(=O)(=O)N(C)CCO)ccc1-2 nan
1611638 53143 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 2 10 3.2 CCOC(=O)Cc1csc(NC(=O)CSc2nc(N)c3c(C)c(C)sc3n2)n1 nan
CHEMBL1598169 53143 17 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 7 2 10 3.2 CCOC(=O)Cc1csc(NC(=O)CSc2nc(N)c3c(C)c(C)sc3n2)n1 nan
16010773 53146 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.2 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cc(C)cc3C)c2=O)cc1 nan
CHEMBL1598197 53146 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 458 6 1 7 3.2 COc1ccc(Cn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cc(C)cc3C)c2=O)cc1 nan
2958808 53148 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 2 4 3.7 Cc1nc(NC(=S)NC(=O)COc2ccccc2Cl)ccc1Br nan
CHEMBL1598226 53148 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 4 2 4 3.7 Cc1nc(NC(=S)NC(=O)COc2ccccc2Cl)ccc1Br nan
921716 53206 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 4.9 Cc1ccc(O)c(C2=Nc3ccccc3N=C(c3ccco3)C2)c1 nan
CHEMBL1598745 53206 10 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 1 4 4.9 Cc1ccc(O)c(C2=Nc3ccccc3N=C(c3ccco3)C2)c1 nan
3284133 53214 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 10 2 6 4.2 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCN(C(C)C)C3)cc1 nan
CHEMBL1598836 53214 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 534 10 2 6 4.2 CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCN(C(C)C)C3)cc1 nan
7326265 53265 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 2 5 3.5 CC(=O)Nc1ccc(C(=O)Nc2nnc(CCc3ccccc3)s2)cc1 nan
CHEMBL1599247 53265 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 6 2 5 3.5 CC(=O)Nc1ccc(C(=O)Nc2nnc(CCc3ccccc3)s2)cc1 nan
16009345 53280 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 0 6 4.0 COc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
CHEMBL1599358 53280 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 364 5 0 6 4.0 COc1cccc(OCc2cc(=O)n3c(-c4ccccc4)csc3n2)c1 nan
16024944 53319 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 4.8 Cc1cccc(N2CCN(c3ccc(C(=O)O)cc3NC(=O)c3ccccc3F)CC2C)c1 nan
CHEMBL1599731 53319 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 5 2 4 4.8 Cc1cccc(N2CCN(c3ccc(C(=O)O)cc3NC(=O)c3ccccc3F)CC2C)c1 nan
6536107 53364 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 5.2 Cc1ccc(-c2csc(/C=C3\SC(C)C(=O)N3CC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1600183 53364 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 5.2 Cc1ccc(-c2csc(/C=C3\SC(C)C(=O)N3CC(=O)Nc3ccccc3F)n2)cc1 nan
733979 53374 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 1 4 2.5 CC(=O)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 nan
CHEMBL1600285 53374 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 2 1 4 2.5 CC(=O)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 nan
2999237 53379 3 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 2.8 CCCCn1c(-c2ccsc2)nc2c1c(=O)[nH]c(=O)n2CCC nan
CHEMBL1600302 53379 3 None -1 3 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 2.8 CCCCn1c(-c2ccsc2)nc2c1c(=O)[nH]c(=O)n2CCC nan
3946061 53421 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 3.2 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NCc5ccccc5)cnc4c3cc2CO1 nan
CHEMBL1600688 53421 12 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 4 1 7 3.2 CC1(C)Cc2nc3sc4c(=O)n(CC(=O)NCc5ccccc5)cnc4c3cc2CO1 nan
16019821 53424 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
CHEMBL1600701 53424 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 2 6 3.4 CCOc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3ccc4nc(O)ccc4c3)C2)cc1 nan
648853 53432 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.2 Cc1ccc(C(=O)Nc2nc3ccccc3c(=O)s2)cc1 nan
CHEMBL1600749 53432 16 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 296 2 1 4 3.2 Cc1ccc(C(=O)Nc2nc3ccccc3c(=O)s2)cc1 nan
1326969 53492 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 4 5.1 Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c(C)c1 nan
CHEMBL1601297 53492 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 372 5 1 4 5.1 Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c(C)c1 nan
20949434 53495 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 2 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CC(=O)N4)CC2)cc1 nan
CHEMBL1601336 53495 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 4 2 6 1.7 CC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CC(=O)N4)CC2)cc1 nan
16015783 53506 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 6 1 6 6.2 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(Cl)cc4)oc4ccccc34)no2)cc1 nan
CHEMBL1601476 53506 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 472 6 1 6 6.2 COc1ccc(-c2cc(C(=O)Nc3c(C(=O)c4ccc(Cl)cc4)oc4ccccc34)no2)cc1 nan
3579351 53546 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 0 7 4.2 COc1ccc(-n2c(SCC(=O)C(C)(C)C)nc3ccsc3c2=O)cc1 nan
CHEMBL1601921 53546 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 0 7 4.2 COc1ccc(-n2c(SCC(=O)C(C)(C)C)nc3ccsc3c2=O)cc1 nan
16034721 53612 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 7 4.3 Cc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4)cc3nc2s1 nan
CHEMBL1602585 53612 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 5 2 7 4.3 Cc1ccccc1Nc1nn2c(=O)c3ccc(C(=O)NCc4ccccc4)cc3nc2s1 nan
3938730 53652 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 2 4 6.4 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)NCc3ccc(Cl)cc3)sc2n1 nan
CHEMBL1602945 53652 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 483 5 2 4 6.4 Cc1cc(C)c2c(NC(=O)c3ccccc3Cl)c(C(=O)NCc3ccc(Cl)cc3)sc2n1 nan
3343394 53732 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 2 1 6 5.1 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccc(Br)cc2)CO1 nan
CHEMBL1603651 53732 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 2 1 6 5.1 CC1(C)Cc2c(sc3c2c(N)nc(=S)n3Cc2ccc(Br)cc2)CO1 nan
5223767 53733 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 4 3.3 Cc1cc2cc(CNC(=O)Cc3ccc([N+](=O)[O-])cc3)ccc2n1C nan
CHEMBL1603656 53733 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 337 5 1 4 3.3 Cc1cc2cc(CNC(=O)Cc3ccc([N+](=O)[O-])cc3)ccc2n1C nan
16030948 53750 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.1 O=C(CSc1ccc2nc(-c3ccccc3)cn2n1)Nc1ccccc1C(F)(F)F nan
CHEMBL1603757 53750 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 1 5 5.1 O=C(CSc1ccc2nc(-c3ccccc3)cn2n1)Nc1ccccc1C(F)(F)F nan
2791873 53782 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.0 CCOC(=O)c1cnc2ccc(Br)cc2c1NCC(C)O nan
CHEMBL1603951 53782 13 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 5 2 5 3.0 CCOC(=O)c1cnc2ccc(Br)cc2c1NCC(C)O nan
16014801 53895 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 4.1 Cc1cccc(CSc2nc(=O)c3c(n2C)NC(=O)CC3c2cc(F)cc(F)c2)c1 nan
CHEMBL1605009 53895 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 4 1 5 4.1 Cc1cccc(CSc2nc(=O)c3c(n2C)NC(=O)CC3c2cc(F)cc(F)c2)c1 nan
135435545 53910 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 2 4 2.3 NC1=C(c2nc3ccccc3[nH]2)C(=O)CN1c1ccccc1 nan
CHEMBL1605162 53910 21 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 290 2 2 4 2.3 NC1=C(c2nc3ccccc3[nH]2)C(=O)CN1c1ccccc1 nan
1511904 53925 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 4 3.8 O=C(O)c1cn(-c2ccc(N3CCCC3)c(F)c2)c2c(F)c(F)c(F)cc2c1=O nan
CHEMBL1605292 53925 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 3 1 4 3.8 O=C(O)c1cn(-c2ccc(N3CCCC3)c(F)c2)c2c(F)c(F)c(F)cc2c1=O nan
1961588 54004 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 3 0 6 4.9 Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(-c3ccc(Cl)cc3Cl)nc21 nan
CHEMBL1605870 54004 9 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 451 3 0 6 4.9 Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(-c3ccc(Cl)cc3Cl)nc21 nan
16001902 54019 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 3.3 Cc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3cccc4nsnc34)C2)cc1C nan
CHEMBL1605982 54019 3 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 4 1 6 3.3 Cc1ccc(NC(=O)C2CCCN(S(=O)(=O)c3cccc4nsnc34)C2)cc1C nan
16031132 54107 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 5 4.5 CN(C)c1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
CHEMBL1606681 54107 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 430 6 2 5 4.5 CN(C)c1ccc(CNC(=O)c2ccccc2NC(=O)c2nsc3ccccc23)cc1 nan
2931173 54113 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 2 3 4.9 CCCCn1c(N=C(S)Nc2ccccc2)nc2ccccc21 nan
CHEMBL1606716 54113 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 324 5 2 3 4.9 CCCCn1c(N=C(S)Nc2ccccc2)nc2ccccc21 nan
1481761 54229 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 4.1 COc1ccc(-c2c(C)nc3c(-c4ccc(F)cc4)cnn3c2N)cc1 nan
CHEMBL1607515 54229 24 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 3 1 5 4.1 COc1ccc(-c2c(C)nc3c(-c4ccc(F)cc4)cnn3c2N)cc1 nan
16030158 54265 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 7 3.2 Cc1nn(CC(=O)NCc2ccc(N(C)C)cc2)c(=O)c2c(C)n(-c3ccc(Cl)cc3)nc12 nan
CHEMBL1607845 54265 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 6 1 7 3.2 Cc1nn(CC(=O)NCc2ccc(N(C)C)cc2)c(=O)c2c(C)n(-c3ccc(Cl)cc3)nc12 nan
786570 54279 39 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 1 1 3 3.8 O=c1c2cc(Br)ccc2[nH]c(=S)n1-c1ccccc1 nan
CHEMBL1608028 54279 39 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 1 1 3 3.8 O=c1c2cc(Br)ccc2[nH]c(=S)n1-c1ccccc1 nan
744022 54376 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 4 1 4 3.8 COCc1cc(C)nc(Nc2ccc(C)c(C)c2)c1C#N nan
CHEMBL1608862 54376 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 281 4 1 4 3.8 COCc1cc(C)nc(Nc2ccc(C)c(C)c2)c1C#N nan
20868577 54393 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nc5ccccc5c4o3)CC2)cc1 nan
CHEMBL1609003 54393 4 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 413 3 0 5 4.5 CC(=O)c1ccc(N2CCN(C(=O)c3cc4c(C)nc5ccccc5c4o3)CC2)cc1 nan
16015522 54399 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 3.5 COc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)cc1 nan
CHEMBL1609032 54399 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 443 6 1 7 3.5 COc1ccc(C(=O)Nc2ccc3nc(SCC(=O)N4CCOCC4)sc3c2)cc1 nan
3128209 54487 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 8 1.5 NS(=O)(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 nan
CHEMBL1609744 54487 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 335 4 2 8 1.5 NS(=O)(=O)c1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1 nan
16026888 54557 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 0 8 3.6 COc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
CHEMBL1610338 54557 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 5 0 8 3.6 COc1ccccc1C(=O)OCc1cc(=O)n2nc(C3CCCCC3)sc2n1 nan
16015736 54581 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 4 3.3 Cc1ccc(C(C)C)c(OCC(=O)N2CCN(CCc3ccncc3)CC2)c1 nan
CHEMBL1610516 54581 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 7 0 4 3.3 Cc1ccc(C(C)C)c(OCC(=O)N2CCN(CCc3ccncc3)CC2)c1 nan
2220915 54655 11 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 5 4.9 COc1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)cc1OC nan
CHEMBL1611237 54655 11 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 7 1 5 4.9 COc1ccc(CCNC(=O)c2cc(-c3ccccn3)nc3c(Cl)cccc23)cc1OC nan
16030297 54683 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 5 4.9 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCc2ccccc21 nan
CHEMBL1611407 54683 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 441 6 0 5 4.9 COc1ccccc1Cc1nc2ccccc2nc1SCC(=O)N1CCc2ccccc21 nan
903550 54727 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 4 1 5 2.5 CCOC(=O)c1sc(NC(=O)CC)c(C#N)c1C nan
CHEMBL1611829 54727 18 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 4 1 5 2.5 CCOC(=O)c1sc(NC(=O)CC)c(C#N)c1C nan
2804057 54755 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 206 0 2 2 3.1 Cc1c(C)c(C)c2[nH]c(S)nc2c1C nan
CHEMBL1612138 54755 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 206 0 2 2 3.1 Cc1c(C)c(C)c2[nH]c(S)nc2c1C nan
16019436 54822 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(C)c(CSc2ccc3nnc(CCNS(=O)(=O)c4ccccc4)n3n2)c1 nan
CHEMBL1612674 54822 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 8 1 7 3.6 Cc1ccc(C)c(CSc2ccc3nnc(CCNS(=O)(=O)c4ccccc4)n3n2)c1 nan
4152434 54836 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 5 5.7 CC(C)c1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
CHEMBL1612783 54836 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 393 5 1 5 5.7 CC(C)c1ccc(NC(=O)CSc2ncnc3c2sc2ccccc23)cc1 nan
16034221 54872 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 1.1 CCOC(=O)N1CCN(S(=O)(=O)N2CCCC(C(=O)NCc3cc(OC)ccc3OC)C2)CC1 nan
CHEMBL1613162 54872 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 8 1 7 1.1 CCOC(=O)N1CCN(S(=O)(=O)N2CCCC(C(=O)NCc3cc(OC)ccc3OC)C2)CC1 nan
3238969 54876 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 1 4 5.6 O=C(Nc1ccc2oc(-c3ccccc3Cl)nc2c1)c1cncc(Br)c1 nan
CHEMBL1613230 54876 4 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 3 1 4 5.6 O=C(Nc1ccc2oc(-c3ccccc3Cl)nc2c1)c1cncc(Br)c1 nan
16033448 54887 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 Cc1cc(C)c(NC(=O)c2nc3ccccc3nc2N2CCCCC2)c(C)c1 nan
CHEMBL1613324 54887 6 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 374 3 1 4 4.8 Cc1cc(C)c(NC(=O)c2nc3ccccc3nc2N2CCCCC2)c(C)c1 nan
2138172 54892 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 3.1 C=CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
CHEMBL1613374 54892 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 6 1 6 3.1 C=CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)nc1C nan
17585635 55172 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
73401607 55172 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
CHEMBL1311226 55172 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
CHEMBL1617414 55172 5 None -11 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 283 2 0 1 3.8 Cn1cc(/C=C/c2cc[n+](C)cc2)c2cc(Cl)ccc21 nan
424003 55309 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
CHEMBL1359356 55309 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
CHEMBL1618556 55309 30 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 202 1 1 2 1.8 NCc1cc2c3c(c1)CCCN3CCC2 nan
719481 55319 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
CHEMBL1379055 55319 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
CHEMBL1618658 55319 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 3 1 4 4.5 COc1ccc(-n2cc(-c3ccc(Cl)cc3)nc2S)cc1 nan
1453026 55668 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
CHEMBL1442637 55668 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
CHEMBL1621750 55668 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 8 2 7 3.6 COc1ccc(C(=O)Nc2ccc(NC(=O)c3cc(OC)c(OC)c(OC)c3)cn2)cc1 nan
5044272 55917 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1524152 55917 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
CHEMBL1623691 55917 6 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 484 9 1 7 4.8 CCN(CC)CCn1c(SCC(=O)Nc2ccc(F)cc2)nc2c(sc3ccccc32)c1=O nan
3149296 55949 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
5768586 55949 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
CHEMBL1508982 55949 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
CHEMBL1623968 55949 6 None -2 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 389 2 0 3 6.1 CCN1/C(=C/c2ccc3cc(C)ccc3[n+]2C)Sc2ccc3sccc3c21 nan
1956404 55975 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
CHEMBL1556245 55975 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
CHEMBL1624228 55975 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 5 1 7 3.5 COCCN1CCn2c(nc3cc(Nc4nnc(C)c5ccccc45)ccc32)C1 nan
3602384 56110 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
CHEMBL1602214 56110 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
CHEMBL1625426 56110 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 5 1 3 4.5 Cc1ccc(CNC(=O)c2cc3c(s2)CN(Cc2ccccc2)C3)cc1 nan
2151347 71981 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 0 4 3.3 C#CCn1/c(=N/C(=O)c2ccco2)sc2cccc(Cl)c21 nan
CHEMBL1973713 71981 10 None -3 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 2 0 4 3.3 C#CCn1/c(=N/C(=O)c2ccco2)sc2cccc(Cl)c21 nan
741794 72287 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 4 3.1 Cc1c(C(C)(C)C)s/c(=N/C(=O)c2ccccc2O)n1C nan
CHEMBL1983034 72287 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 1 1 4 3.1 Cc1c(C(C)(C)C)s/c(=N/C(=O)c2ccccc2O)n1C nan
9583974 72549 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 2 7 5.1 COc1cccc(/C=N/NC(=O)c2oc3nc(-c4ccccc4)cc(-c4ccco4)c3c2N)c1 nan
CHEMBL1991618 72549 2 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 6 2 7 5.1 COc1cccc(/C=N/NC(=O)c2oc3nc(-c4ccccc4)cc(-c4ccco4)c3c2N)c1 nan
135498048 72632 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 3 2 6 0.8 Cc1nonc1C(=O)N/N=C/c1ccc(O)cc1 nan
CHEMBL1994596 72632 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 246 3 2 6 0.8 Cc1nonc1C(=O)N/N=C/c1ccc(O)cc1 nan
1362920 95770 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 nan
CHEMBL258549 95770 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 5 5.1 COc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 nan
2150885 107617 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 5 3.3 COc1ccc(OC)c2c1s/c(=N\C(=O)C1CCCCC1)n2C nan
CHEMBL3189890 107617 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 334 3 0 5 3.3 COc1ccc(OC)c2c1s/c(=N\C(=O)C1CCCCC1)n2C nan
3604296 107779 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 2.1 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
CHEMBL3191753 107779 14 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 5 0 7 2.1 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(F)ccc21 nan
1389664 107975 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 0 8 3.2 COc1cc(/C=c2\sc3nc(=O)c(-c4ccccc4)nn3c2=O)ccc1OCCC(C)C nan
CHEMBL3193918 107975 9 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 0 8 3.2 COc1cc(/C=c2\sc3nc(=O)c(-c4ccccc4)nn3c2=O)ccc1OCCC(C)C nan
2321009 108049 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 0 4 3.4 Cc1ccc2c(c1)s/c(=N/C(=O)c1cccs1)n2C nan
CHEMBL3194826 108049 7 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 288 1 0 4 3.4 Cc1ccc2c(c1)s/c(=N/C(=O)c1cccs1)n2C nan
3245289 108054 11 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 0 8 2.0 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(OC)ccc21 nan
CHEMBL3194890 108054 11 None -31 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 6 0 8 2.0 CCOC(=O)Cn1/c(=N/C(=O)CSC(C)=O)sc2cc(OC)ccc21 nan
4668650 108326 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 1.5 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(N)(=O)=O)ccc21 nan
CHEMBL3197833 108326 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 5 1 8 1.5 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(S(N)(=O)=O)ccc21 nan
2150918 108381 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 6 3.0 COc1ccc(C)c2s/c(=N\C(=O)c3cccc(N4C(=O)CCC4=O)c3)n(C)c12 nan
CHEMBL3198311 108381 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 409 3 0 6 3.0 COc1ccc(C)c2s/c(=N\C(=O)c3cccc(N4C(=O)CCC4=O)c3)n(C)c12 nan
135460447 108394 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 3 3 6 1.9 Nc1c(Cl)ncnc1N/N=C/c1ccc(O)cc1 nan
CHEMBL3198494 108394 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 3 3 6 1.9 Nc1c(Cl)ncnc1N/N=C/c1ccc(O)cc1 nan
6184027 108673 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 12 1 9 0.8 COCCCn1c(=O)/c(=C\c2ccc(OC(F)F)c(OC)c2)s/c1=C(/C#N)C(=O)NCCOC nan
CHEMBL3207685 108673 1 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 497 12 1 9 0.8 COCCCn1c(=O)/c(=C\c2ccc(OC(F)F)c(OC)c2)s/c1=C(/C#N)C(=O)NCCOC nan
2150849 108705 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 7 3.3 COc1cc(C(=O)/N=c2\sc3c(C)ccc(OC)c3n2C)cc(OC)c1OC nan
CHEMBL3208227 108705 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 5 0 7 3.3 COc1cc(C(=O)/N=c2\sc3c(C)ccc(OC)c3n2C)cc(OC)c1OC nan
5122885 108834 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccccc2Br)n(C)c1C nan
CHEMBL3209816 108834 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 0 5 3.1 CCOC(=O)c1s/c(=N\C(=O)c2ccccc2Br)n(C)c1C nan
9631393 108927 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 3.2 O=C(N/N=C/c1ccc2nccnc2c1)c1ccc(Br)cc1 nan
CHEMBL3211205 108927 6 None -1 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 3 1 4 3.2 O=C(N/N=C/c1ccc2nccnc2c1)c1ccc(Br)cc1 nan
4128025 108941 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 0 6 2.4 COc1cccc(C(=O)/N=c2\sc3cc(S(C)(=O)=O)ccc3n2C)c1 nan
CHEMBL3211378 108941 15 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 0 6 2.4 COc1cccc(C(=O)/N=c2\sc3cc(S(C)(=O)=O)ccc3n2C)c1 nan
7161820 108961 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 5 2.7 CCOC(=O)Cn1/c(=N/C(=O)CC)sc2c(C)cc(C)cc21 nan
CHEMBL3211674 108961 10 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 320 4 0 5 2.7 CCOC(=O)Cn1/c(=N/C(=O)CC)sc2c(C)cc(C)cc21 nan
2150987 109171 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 0 5 2.5 CCCC(=O)/N=c1\sc2c(OC)ccc(OC)c2n1C nan
CHEMBL3214516 109171 14 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 294 4 0 5 2.5 CCCC(=O)/N=c1\sc2c(OC)ccc(OC)c2n1C nan
3213263 112611 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
CHEMBL3197118 112611 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
CHEMBL3302243 112611 5 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 401 5 0 7 3.1 COCC/N=C1\Sc2nc3cc4c(cc3cc2CN1CC1CCCO1)OCO4 nan
6540428 184864 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
CHEMBL3989558 184864 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
CHEMBL485253 184864 1 None -37 2 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 4 2 4 1.9 CCC(CO)NC(=O)[C@@H]1C=C2c3cccc4c3c(cn4C)C[C@H]2N(C)C1 nan
846186 193372 26 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 3 3 3.0 Cc1nc2ccc(-c3nc4cc(N)ccc4[nH]3)cc2[nH]1 nan
CHEMBL525103 193372 26 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 263 1 3 3 3.0 Cc1nc2ccc(-c3nc4cc(N)ccc4[nH]3)cc2[nH]1 nan
2850154 197896 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 2 1 2.1 CC1=CC(c2ccccc2)NC(=S)N1 nan
CHEMBL572806 197896 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 204 1 2 1 2.1 CC1=CC(c2ccccc2)NC(=S)N1 nan
138884 200002 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 4 4.2 COc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(OC)c3)c2)c1 nan
CHEMBL595273 200002 16 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 6 2 4 4.2 COc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(OC)c3)c2)c1 nan
16020583 202378 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 0 5 4.2 Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c(=O)c2cc(F)c(N3CCCCC3)cc21 nan
CHEMBL610622 202378 12 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 434 3 0 5 4.2 Cn1cc(S(=O)(=O)c2cccc(Cl)c2)c(=O)c2cc(F)c(N3CCCCC3)cc21 nan
1361408 21397 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 6.1 O=C(Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1)c1cc2ccccc2o1 nan
CHEMBL1314585 21397 9 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 3 1 4 6.1 O=C(Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1)c1cc2ccccc2o1 nan
1369231 21522 8 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 2 5 5.5 O=C(COc1ccc(Cl)cc1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)c(O)c1 nan
CHEMBL1316173 21522 8 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 2 5 5.5 O=C(COc1ccc(Cl)cc1)Nc1ccc(-c2nc3cc(Cl)ccc3o2)c(O)c1 nan
16033420 21917 3 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1ccc(NC(=O)c2nc3ccccc3n(C)c2=O)cc1 nan
CHEMBL1320318 21917 3 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 321 3 1 5 2.4 CC(=O)c1ccc(NC(=O)c2nc3ccccc3n(C)c2=O)cc1 nan
16019599 22408 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 8 4.5 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)c(C)c1 nan
CHEMBL1324615 22408 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 4 1 8 4.5 Cc1ccc(Nc2nc3c(S(=O)(=O)c4ccccc4)nnn3c3ccsc23)c(C)c1 nan
16033879 22477 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 8 3.2 CCOC(=O)c1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 nan
CHEMBL1325210 22477 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 366 4 1 8 3.2 CCOC(=O)c1ccc(Nc2nn3c(=O)c4ccccc4nc3s2)cc1 nan
1115824 23205 15 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
CHEMBL1331382 23205 15 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 5 1 5 6.1 N#Cc1c(C(F)(F)F)cc(-c2cccs2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
460749 23549 8 None -11 6 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 7 0.7 Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 nan
CHEMBL1334062 23549 8 None -11 6 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 303 1 0 7 0.7 Cn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 nan
16746586 24533 0 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 3 8 0.2 CCCN=C1C(=O)C2=C(C(O)=C1C)N1CC3NC3[C@@]1(OC)C2COC(N)=O nan
CHEMBL1342436 24533 0 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 5 3 8 0.2 CCCN=C1C(=O)C2=C(C(O)=C1C)N1CC3NC3[C@@]1(OC)C2COC(N)=O nan
2128809 27045 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 5 1 6 3.2 Cc1cc(C)c(C(=O)CSc2nnc(O)n2C2CC2)cc1C nan
CHEMBL1365084 27045 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 317 5 1 6 3.2 Cc1cc(C)c(C(=O)CSc2nnc(O)n2C2CC2)cc1C nan
15988395 27173 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 2 3 3.4 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Cl)cc3)c(=O)[nH]c2C1 nan
CHEMBL1366158 27173 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 344 2 2 3 3.4 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Cl)cc3)c(=O)[nH]c2C1 nan
2168191 28079 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.8 Cc1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
CHEMBL1372901 28079 14 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 421 4 1 5 5.8 Cc1sc(NC(=O)C2c3ccccc3Oc3ccccc32)c(C(=O)OC(C)C)c1C nan
4578108 29095 7 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 5 2.4 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc2ncsc2c1 nan
CHEMBL1381180 29095 7 None 1 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 323 2 2 5 2.4 O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccc2ncsc2c1 nan
15988012 30003 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1388847 30003 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 397 6 1 8 2.6 COc1ccccc1NC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
16024702 32300 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 9 1 7 4.3 COCCn1c(SCC(=O)c2ccc(C)cc2C)nc2cc(C(=O)NC3CCCC3)ccc2c1=O nan
CHEMBL1410231 32300 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 9 1 7 4.3 COCCn1c(SCC(=O)c2ccc(C)cc2C)nc2cc(C(=O)NC3CCCC3)ccc2c1=O nan
16025307 33194 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccccc1CNC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
CHEMBL1417794 33194 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccccc1CNC(=O)CSc1ncc2c(n1)-c1ccc(Cl)cc1N(Cc1ccccc1)S2(=O)=O nan
4658659 35378 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 5 4.9 CCOC(=O)CSc1nc(-c2ccc(Cl)cc2)cc(C(F)(F)F)c1C#N nan
CHEMBL1437587 35378 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 0 5 4.9 CCOC(=O)CSc1nc(-c2ccc(Cl)cc2)cc(C(F)(F)F)c1C#N nan
16018194 40620 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 4 4.1 O=C(CCCn1c(=O)c2cccn2c2ccccc21)NCc1ccccc1Br nan
CHEMBL1483956 40620 7 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 437 6 1 4 4.1 O=C(CCCn1c(=O)c2cccn2c2ccccc21)NCc1ccccc1Br nan
1046621 40694 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 3 1 6 5.4 Cc1c(Cl)cccc1NC(=O)c1cc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2n1 nan
CHEMBL1484483 40694 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 3 1 6 5.4 Cc1c(Cl)cccc1NC(=O)c1cc2nc(-c3ccc4c(c3)OCO4)cc(C(F)(F)F)n2n1 nan
16025305 44121 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
CHEMBL1515325 44121 6 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 566 8 1 7 4.9 COc1ccc(CNC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc1 nan
2119988 44606 15 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 6 4.7 CCOC(=O)c1sc2nc(Cc3ccc(Cl)cc3)nc(S)c2c1C nan
CHEMBL1520325 44606 15 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 4 1 6 4.7 CCOC(=O)c1sc2nc(Cc3ccc(Cl)cc3)nc(S)c2c1C nan
3368526 47198 16 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 6 3.9 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Br)cc2)o1 nan
CHEMBL1543365 47198 16 None 2 2 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 4 1 6 3.9 Cc1ccc(C(=O)C2=C(O)C(=O)N(c3ncccn3)C2c2ccc(Br)cc2)o1 nan
16020714 52374 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 6 3.8 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1ccc(OC)cc1)cn2CC nan
CHEMBL1589919 52374 11 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 432 7 0 6 3.8 CCN(CC)c1cc2c(cc1F)c(=O)c(S(=O)(=O)c1ccc(OC)cc1)cn2CC nan
1164393 52392 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 6 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
CHEMBL1590134 52392 10 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 398 7 2 6 2.9 CCOc1ccccc1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 nan
2254266 108074 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 0 6 4.7 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\Cc1ccccc1 nan
CHEMBL3195210 108074 12 None - 1 Human 5.4 pPotency = 5.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 423 5 0 6 4.7 C=CCN1C(=O)/C(=C2/Sc3ccc(OC)cc3N2C)S/C1=N\Cc1ccccc1 nan
7424526 40403 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 7 0.0 COCCNC(=O)C(=O)Nc1c2c(nn1-c1ccccc1)CS(=O)(=O)C2 nan
CHEMBL1482031 40403 11 None - 1 Human 4.4 pPotency = 4.4 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 378 5 2 7 0.0 COCCNC(=O)C(=O)Nc1c2c(nn1-c1ccccc1)CS(=O)(=O)C2 nan
4890321 19708 8 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 2 6 3.7 Cc1ccc(NC2=NC(c3ccc(F)cc3)n3c(nc(C)cc3=O)N2)c(C)c1 nan
CHEMBL1300954 19708 8 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 377 2 2 6 3.7 Cc1ccc(NC2=NC(c3ccc(F)cc3)n3c(nc(C)cc3=O)N2)c(C)c1 nan
7119211 21472 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.6 COc1ccc(-c2nc(CCNC(=O)c3c(F)cccc3Cl)cs2)cc1 nan
CHEMBL1315624 21472 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 6 1 4 4.6 COc1ccc(-c2nc(CCNC(=O)c3c(F)cccc3Cl)cs2)cc1 nan
16028928 21599 5 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 2 6 3.0 COC(=O)c1ccc(NC(=O)C(=O)NCCc2csc(-c3ccc(F)cc3)n2)cc1 nan
CHEMBL1317331 21599 5 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 6 2 6 3.0 COC(=O)c1ccc(NC(=O)C(=O)NCCc2csc(-c3ccc(F)cc3)n2)cc1 nan
16009640 22177 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 4.5 CCOc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1322592 22177 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 7 1 7 4.5 CCOc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
15988993 22411 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 4 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
CHEMBL1324637 22411 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 452 5 1 4 5.7 COc1ccc(CNC(=O)c2cc(-c3ccc(Br)s3)nc3ccccc23)cc1 nan
682221 25383 20 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 4 3 8 0.2 CC(C)OC(=O)CNc1nnc(S)nc1O nan
CHEMBL1349621 25383 20 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 244 4 3 8 0.2 CC(C)OC(=O)CNc1nnc(S)nc1O nan
16009655 26080 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 4.4 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
CHEMBL1355671 26080 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 5 1 6 4.4 Cc1ccc(NC(=O)Cn2c(=O)n(Cc3ccccc3)c(=O)c3sc4ccccc4c32)cc1 nan
16019300 27218 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 6 1 10 4.6 COc1cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc(OC)c1 nan
CHEMBL1366490 27218 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 501 6 1 10 4.6 COc1cc(Nc2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc(OC)c1 nan
16024750 29239 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1382499 29239 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
5302633 30960 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 6 2 5 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
CHEMBL1398493 30960 12 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 493 6 2 5 6.6 CCc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2NC(=O)c2ccccc2OC)cc1 nan
16009653 35628 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 4 5.2 Cc1ccccc1OCC(=O)Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12 nan
CHEMBL1439712 35628 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 418 6 2 4 5.2 Cc1ccccc1OCC(=O)Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12 nan
3522635 39018 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
CHEMBL1468421 39018 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 498 7 1 7 2.8 CCN(CC)S(=O)(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc(=O)c3ccccc3o2)c1 nan
16018176 40010 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.2 COc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
CHEMBL1478735 40010 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.2 COc1ccc(CNC(=O)c2oc3c(c2C)-c2nn(Cc4ccc(Cl)cc4)cc2CC3)cc1 nan
3432810 40167 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 4 5.7 O=C(Nc1ccc(-c2nc3ccccc3s2)c(O)c1)c1ccc(Br)cc1 nan
CHEMBL1479998 40167 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 424 3 2 4 5.7 O=C(Nc1ccc(-c2nc3ccccc3s2)c(O)c1)c1ccc(Br)cc1 nan
1234246 41347 10 None -1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 1 1 5 3.0 Cc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
CHEMBL1489869 41347 10 None -1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 270 1 1 5 3.0 Cc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
6800739 44553 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 4.6 CCc1ccc2n(-c3ccc(OC)cc3)c([S-])c(C(=O)Nc3cc(C)cc(C)c3)[n+]2c1 nan
CHEMBL1519802 44553 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 431 5 1 4 4.6 CCc1ccc2n(-c3ccc(OC)cc3)c([S-])c(C(=O)Nc3cc(C)cc(C)c3)[n+]2c1 nan
1744296 48391 24 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 4 6.7 N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
CHEMBL1555056 48391 24 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 455 6 1 4 6.7 N#Cc1c(-c2ccccc2)cc(-c2ccccc2)nc1SCC(=O)Nc1ccc(Cl)cc1 nan
15988419 52545 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 2 3 3.5 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Br)cc3)c(=O)[nH]c2C1 nan
CHEMBL1592108 52545 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 388 2 2 3 3.5 CC1(C)CC(=O)c2cc(C(=O)Nc3ccc(Br)cc3)c(=O)[nH]c2C1 nan
1863779 72234 15 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 8 2.4 CC1=CC=CN2C(=O)C(=C\c3sc(S)nc3O)/C(=N/CCCN3CCOCC3)N=C12 nan
CHEMBL1981539 72234 15 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 445 5 2 8 2.4 CC1=CC=CN2C(=O)C(=C\c3sc(S)nc3O)/C(=N/CCCN3CCOCC3)N=C12 nan
755656 172690 49 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2cccs2)nc2ccc(Br)cc12 nan
CHEMBL450135 172690 49 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 2 1 3 4.4 O=C(O)c1cc(-c2cccs2)nc2ccc(Br)cc12 nan
5808 176780 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
CHEMBL1257092 176780 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
CHEMBL460574 176780 23 None -1 2 Human 6.3 pPotency = 6.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 211 4 4 4 1.1 CC(C)NC[C@@H](O)c1ccc(O)c(O)c1 nan
4905097 26938 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 6 1 5 2.2 CCCC(=O)Nc1ccc2c(c1)nc1n2CCN(CCOC)C1 nan
CHEMBL1364140 26938 10 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 6 1 5 2.2 CCCC(=O)Nc1ccc2c(c1)nc1n2CCN(CCOC)C1 nan
995260 31068 13 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
CHEMBL1399507 31068 13 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
15990423 32256 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 5.3 CCOc1ccccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1409911 32256 7 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 1 5 5.3 CCOc1ccccc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
16024826 32931 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccc(F)cc5)CC4)ccc3c2)CC1 nan
CHEMBL1415463 32931 6 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 468 4 0 5 4.1 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccc(F)cc5)CC4)ccc3c2)CC1 nan
3242125 38934 4 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 1.7 COc1ccc(OC)c(CNC(=O)C2CCN(C(=O)N(C)C)CC2)c1 nan
CHEMBL1467628 38934 4 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 349 5 1 4 1.7 COc1ccc(OC)c(CNC(=O)C2CCN(C(=O)N(C)C)CC2)c1 nan
3501359 42760 17 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 8 2.6 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3n(CC3CCCO3)c2=N)cc1 nan
CHEMBL1501993 42760 17 None - 1 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 473 6 2 8 2.6 COc1ccc(CNC(=O)c2cc3c(=O)n4cccc(C)c4nc3n(CC3CCCO3)c2=N)cc1 nan
1234242 46570 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 6 3.1 CCOc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
CHEMBL1538068 46570 3 None 1 2 Human 5.3 pPotency = 5.3 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 300 3 1 6 3.1 CCOc1ccc(-n2nc3c(S)nnc(C)c3c2C)cc1 nan
20921619 23583 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 2.9 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccc(C)cc3)s2)cc1OC nan
CHEMBL1334300 23583 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 1 8 2.9 COc1ccc(CN(C)S(=O)(=O)c2nnc(NC(=O)c3ccc(C)cc3)s2)cc1OC nan
16024792 25087 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
CHEMBL1347118 25087 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
5762489 25415 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 1 3 4.6 N#C/C(=C/c1ccc(OCc2ccccc2)cc1)C(=O)NC1CCCCC1 nan
CHEMBL1349947 25415 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 360 6 1 3 4.6 N#C/C(=C/c1ccc(OCc2ccccc2)cc1)C(=O)NC1CCCCC1 nan
652632 26996 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 0 8 3.7 COc1cccc(C(=O)CSc2nnc(-c3cc(OC)cc(OC)c3)o2)c1 nan
CHEMBL1364667 26996 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 386 8 0 8 3.7 COc1cccc(C(=O)CSc2nnc(-c3cc(OC)cc(OC)c3)o2)c1 nan
4137748 27429 1 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 1 4 4.0 Cc1cc(NC(=O)c2ccccc2F)nc2c1c(=O)oc1ccccc12 nan
CHEMBL1368254 27429 1 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 2 1 4 4.0 Cc1cc(NC(=O)c2ccccc2F)nc2c1c(=O)oc1ccccc12 nan
701063 28249 18 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.7 COc1ccc(Cl)cc1-c1nnc(S)o1 nan
CHEMBL1374054 28249 18 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 242 2 1 5 2.7 COc1ccc(Cl)cc1-c1nnc(S)o1 nan
16024750 29239 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
CHEMBL1382499 29239 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 4 0 5 3.7 O=S(=O)(c1ccc2nc(N3CCN(c4ccccc4)CC3)ccc2c1)N1CCCCC1 nan
1051489 29364 14 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(NC(=O)CSc2nc(-c3ccc(C)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1383601 29364 14 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 457 6 1 5 5.7 COc1ccc(NC(=O)CSc2nc(-c3ccc(C)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
2185557 29706 9 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 0 6 3.7 COc1ccc(C(=O)/C=C2/Sc3cc4c(cc3N2C)OCO4)cc1 nan
CHEMBL1386474 29706 9 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 341 3 0 6 3.7 COc1ccc(C(=O)/C=C2/Sc3cc4c(cc3N2C)OCO4)cc1 nan
16017568 30664 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccccc3)s2)c1 nan
CHEMBL1394623 30664 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 402 6 1 6 2.9 Cc1cccc(C(=O)Nc2nnc(S(=O)(=O)N(C)Cc3ccccc3)s2)c1 nan
16025297 30699 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 582 8 1 8 5.3 COc1cc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc(OC)c1 nan
CHEMBL1395000 30699 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 582 8 1 8 5.3 COc1cc(NC(=O)CSc2ncc3c(n2)-c2ccc(Cl)cc2N(Cc2ccccc2)S3(=O)=O)cc(OC)c1 nan
2092877 31220 6 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 3.1 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4CCCC4=O)cc3)sc2c1 nan
CHEMBL1400998 31220 6 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 415 4 1 6 3.1 CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(N4CCCC4=O)cc3)sc2c1 nan
681250 33867 16 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 3 3.7 N#Cc1cc2c(nc1SCc1ccccc1)CCC2 nan
CHEMBL1423417 33867 16 None 3 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 266 3 0 3 3.7 N#Cc1cc2c(nc1SCc1ccccc1)CCC2 nan
2994363 37549 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 4 2.3 CN1C(=O)c2ccc(C(=O)Nc3ccc(Br)cn3)cc2C1=O nan
CHEMBL1456212 37549 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 359 2 1 4 2.3 CN1C(=O)c2ccc(C(=O)Nc3ccc(Br)cn3)cc2C1=O nan
54679694 38160 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 8 2 6 3.5 C=CCn1c(=O)c(C(=O)NCCc2ccc(Cl)cc2)c(O)c2cc(OC)c(OC)cc21 nan
CHEMBL1461466 38160 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 442 8 2 6 3.5 C=CCn1c(=O)c(C(=O)NCCc2ccc(Cl)cc2)c(O)c2cc(OC)c(OC)cc21 nan
16814136 38785 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 11 1.1 CCCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1466491 38785 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 435 7 1 11 1.1 CCCc1nc(SCC(=O)Nc2nnc(CC)s2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
16017049 39689 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 6 4.4 CCC(C(=O)N1CCN(c2ccccc2F)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
CHEMBL1475149 39689 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 464 4 0 6 4.4 CCC(C(=O)N1CCN(c2ccccc2F)CC1)n1nc(C)c2sc3ccccc3c2c1=O nan
655498 40616 4 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 7 1 5 3.5 CCOc1ccc2cc(C#N)c(SCC(=O)NC(C)CC)nc2c1 nan
CHEMBL1483885 40616 4 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 7 1 5 3.5 CCOc1ccc2cc(C#N)c(SCC(=O)NC(C)CC)nc2c1 nan
16019676 41058 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
CHEMBL1487718 41058 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 373 5 1 7 2.4 Cn1c(=O)c2sccc2n2c(CCCC(=O)NC3CCCCC3)nnc12 nan
1305684 41070 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
CHEMBL1487797 41070 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 6 1 5 5.5 COc1ccc(-c2cc(C(F)(F)F)c(C#N)c(SCC(=O)Nc3ccccc3F)n2)cc1 nan
4008999 41160 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 4 6.7 CCCCOc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)cc2C)cc1 nan
CHEMBL1488396 41160 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 416 7 1 4 6.7 CCCCOc1ccc(C(=O)Nc2ccc(-c3nc4ccccc4s3)cc2C)cc1 nan
976779 41541 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 4 1 4 2.5 COc1ccc(S(=O)(=O)Nc2ccccn2)c(C)c1C nan
CHEMBL1491184 41541 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 292 4 1 4 2.5 COc1ccc(S(=O)(=O)Nc2ccccn2)c(C)c1C nan
1457998 42485 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 6 2.3 Cc1cc(C)n2c(SCC(=O)NC3CCCCC3)nnc2n1 nan
CHEMBL1499565 42485 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 319 4 1 6 2.3 Cc1cc(C)n2c(SCC(=O)NC3CCCCC3)nnc2n1 nan
1555503 43714 20 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 6 3 8 0.6 CCCCOC(=O)CNc1nnc(S)nc1O nan
CHEMBL1510408 43714 20 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 258 6 3 8 0.6 CCCCOC(=O)CNc1nnc(S)nc1O nan
1484666 43837 15 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 0 6 4.2 COc1ccc(Oc2nc(SC)nc3ccsc23)cc1 nan
CHEMBL1511350 43837 15 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 4 0 6 4.2 COc1ccc(Oc2nc(SC)nc3ccsc23)cc1 nan
23760140 44371 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 9 5 5 -1.6 CC(=O)N[C@@H](CC(=O)N[C@H](CCC(=O)O)C(=O)O)C(=O)O nan
CHEMBL1518212 44371 1 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 9 5 5 -1.6 CC(=O)N[C@@H](CC(=O)N[C@H](CCC(=O)O)C(=O)O)C(=O)O nan
4385342 44680 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 7 1 6 3.2 CCOC(=O)c1sc(NC(=O)CCc2ccc(OC)cc2)nc1C nan
CHEMBL1520883 44680 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 7 1 6 3.2 CCOC(=O)c1sc(NC(=O)CCc2ccc(OC)cc2)nc1C nan
2552702 46598 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.2 O=C(OCc1cc([N+](=O)[O-])cc2c1OCOC2)c1ccccn1 nan
CHEMBL1538293 46598 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 316 4 0 7 2.2 O=C(OCc1cc([N+](=O)[O-])cc2c1OCOC2)c1ccccn1 nan
16021074 48290 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 1 4 4.3 Cc1cc(C)cc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1553439 48290 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 2 1 4 4.3 Cc1cc(C)cc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
16034749 48291 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 2 1 4 4.7 CC1Cn2cc(C(=O)Nc3ccccc3C(F)(F)F)c(=O)c3c(Cl)ccc(c32)O1 nan
CHEMBL1553466 48291 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 422 2 1 4 4.7 CC1Cn2cc(C(=O)Nc3ccccc3C(F)(F)F)c(=O)c3c(Cl)ccc(c32)O1 nan
16019427 48314 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 9 5.0 COc1ccccc1Nc1nc2c(S(=O)(=O)c3ccc(C(C)C)cc3)nnn2c2ccsc12 nan
CHEMBL1553892 48314 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 479 6 1 9 5.0 COc1ccccc1Nc1nc2c(S(=O)(=O)c3ccc(C(C)C)cc3)nnn2c2ccsc12 nan
16024639 49786 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 5 4.1 CCc1ccc(C(=O)c2cn(CC(=O)NCc3ccc(C)cc3)c3nc(C)ccc3c2=O)cc1 nan
CHEMBL1567298 49786 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 453 7 1 5 4.1 CCc1ccc(C(=O)c2cn(CC(=O)NCc3ccc(C)cc3)c3nc(C)ccc3c2=O)cc1 nan
16017791 50550 4 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 5 2.6 Cc1cc(C)cc(-n2ccn(CC(=O)c3ccc(F)cc3)c(=O)c2=O)c1 nan
CHEMBL1574186 50550 4 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 352 4 0 5 2.6 Cc1cc(C)cc(-n2ccn(CC(=O)c3ccc(F)cc3)c(=O)c2=O)c1 nan
935556 51279 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 6 1 5 3.7 O=C(O)c1cccc(CSc2nnc(Cc3ccccc3)o2)c1 nan
CHEMBL1580776 51279 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 326 6 1 5 3.7 O=C(O)c1cccc(CSc2nnc(Cc3ccccc3)o2)c1 nan
3441236 52622 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.2 O=c1c2ccccc2nc2sc(Nc3ccc(F)cc3)nn12 nan
CHEMBL1593132 52622 5 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 312 2 1 6 3.2 O=c1c2ccccc2nc2sc(Nc3ccc(F)cc3)nn12 nan
7199916 52808 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 8 3.5 Cc1cc(NC(=O)CSc2ncnc3c2cnn3-c2cccc(Cl)c2)no1 nan
CHEMBL1595048 52808 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 400 5 1 8 3.5 Cc1cc(NC(=O)CSc2ncnc3c2cnn3-c2cccc(Cl)c2)no1 nan
865684 54166 12 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 4 4.2 COc1ccccc1Nc1nc2cc(C)ccc2cc1C#N nan
CHEMBL1607092 54166 12 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 3 1 4 4.2 COc1ccccc1Nc1nc2cc(C)ccc2cc1C#N nan
135421676 109064 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
135599408 109064 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
137179849 109064 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
CHEMBL3212907 109064 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 313 4 1 5 2.8 Cc1ccccc1CC1SC(N/N=C/c2ccco2)=NC1=O nan
23874512 55396 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1397465 55396 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
CHEMBL1619312 55396 1 None - 1 Human 6.2 pPotency = 6.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 469 7 2 11 1.9 CCCC(=O)Nc1ncnc2c1ncn2[C@@H]1O[C@@H]2OP(=O)(O)OC[C@H]2[C@H]1OC(=O)CCC nan
16019610 10864 10 None -50 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 4 1 8 5.0 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
CHEMBL1172404 10864 10 None -50 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 461 4 1 8 5.0 O=S(=O)(c1cccc(Cl)c1)c1nnn2c1nc(NC1CCCCCC1)c1sccc12 nan
20923126 23117 2 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1C nan
CHEMBL1330832 23117 2 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.5 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCCC1C nan
1425004 23271 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 216 3 3 8 -0.5 COC(=O)CNc1nnc(S)nc1O nan
CHEMBL1331930 23271 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 216 3 3 8 -0.5 COC(=O)CNc1nnc(S)nc1O nan
16024792 25087 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
CHEMBL1347118 25087 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 450 4 0 5 4.0 CC1CCN(S(=O)(=O)c2ccc3nc(N4CCN(c5ccccc5)CC4)ccc3c2)CC1 nan
15989825 26088 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.9 Cc1ccc(CNc2nc3ccc(C)cc3n3nnnc23)cc1 nan
CHEMBL1355740 26088 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 304 3 1 6 2.9 Cc1ccc(CNc2nc3ccc(C)cc3n3nnnc23)cc1 nan
930238 26766 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 1 5 4.1 CC(C)c1nc2sc3c(S)ncnc3c2c2c1CCC2 nan
CHEMBL1362595 26766 10 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 301 1 1 5 4.1 CC(C)c1nc2sc3c(S)ncnc3c2c2c1CCC2 nan
15988284 27680 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccccc3)nnc12 nan
CHEMBL1370040 27680 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 7 1.9 Cn1c(=O)c2sccc2n2c(CCC(=O)NCc3ccccc3)nnc12 nan
7245805 30845 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 1.8 Cc1ccc(CNC(=O)Cn2ccn(-c3ccc(F)cc3)c(=O)c2=O)cc1 nan
CHEMBL1396990 30845 11 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 1.8 Cc1ccc(CNC(=O)Cn2ccn(-c3ccc(F)cc3)c(=O)c2=O)cc1 nan
16025341 30948 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 8 1 6 5.0 O=C(CSc1ncc2c(n1)-c1cc(Cl)ccc1N(Cc1ccccc1)S2(=O)=O)NCCc1ccccc1 nan
CHEMBL1398424 30948 6 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 550 8 1 6 5.0 O=C(CSc1ncc2c(n1)-c1cc(Cl)ccc1N(Cc1ccccc1)S2(=O)=O)NCCc1ccccc1 nan
995260 31068 13 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
CHEMBL1399507 31068 13 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 375 3 1 3 5.3 CCc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2C)s1 nan
3243282 34655 3 None 2 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 1 4 4.3 CCCCn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
CHEMBL1429998 34655 3 None 2 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 308 3 1 4 4.3 CCCCn1c(=S)[nH]c2c(oc3ccc(Cl)cc32)c1=O nan
1007107 35768 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 3 1 4 5.8 Cc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
CHEMBL1441054 35768 14 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 368 3 1 4 5.8 Cc1ccc(-c2nc3cc(NC(=O)c4cc5ccccc5o4)ccc3o2)cc1 nan
16800714 38967 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 9 0.4 CCCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
CHEMBL1468004 38967 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 407 7 1 9 0.4 CCCc1nc(SCC(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 nan
814519 39432 28 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 201 0 2 3 2.4 Sc1[nH]cnc2c3ccccc3nc1-2 nan
CHEMBL1471924 39432 28 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 201 0 2 3 2.4 Sc1[nH]cnc2c3ccccc3nc1-2 nan
44142305 39647 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 5 3.1 Cn1cncc1C#Cc1ccc2cc(C3(O)CCCCC3)oc(=O)c2c1 nan
CHEMBL1474528 39647 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 348 1 1 5 3.1 Cn1cncc1C#Cc1ccc2cc(C3(O)CCCCC3)oc(=O)c2c1 nan
2138538 48883 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1ccc(CCNc2nc3c(-c4cccc(C)c4)nnn3c3ccccc23)cc1OC nan
CHEMBL1559550 48883 12 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 439 7 1 7 4.9 COc1ccc(CCNc2nc3c(-c4cccc(C)c4)nnn3c3ccccc23)cc1OC nan
16028162 49416 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3ccc(F)cc3)cc21 nan
CHEMBL1564507 49416 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 3 2 3 3.7 O=C1CC(c2ccccc2)Cc2[nH]c(=O)c(C(=O)Nc3ccc(F)cc3)cc21 nan
7720817 51363 0 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 1 5 2.9 Sc1nncn2c1cc1oc3ccccc3c12 nan
CHEMBL1581464 51363 0 None 1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 241 0 1 5 2.9 Sc1nncn2c1cc1oc3ccccc3c12 nan
1909591 52099 10 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 3.4 Oc1c2nc3ccc(Br)cc3c-2ncn1Cc1ccncc1 nan
CHEMBL1587545 52099 10 None -1 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 354 2 1 5 3.4 Oc1c2nc3ccc(Br)cc3c-2ncn1Cc1ccncc1 nan
15988964 52513 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCCN(C)CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
CHEMBL1591653 52513 7 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 459 9 1 4 5.6 CCCCN(C)CCCNC(=O)c1cc(-c2ccc(Br)s2)nc2ccccc12 nan
44143234 52661 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 16 3 12 2.5 CCCC[N+](CCCC)(CCCC)CCCC.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H]1O nan
CHEMBL1593759 52661 0 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 588 16 3 12 2.5 CCCC[N+](CCCC)(CCCC)CCCC.Nc1ncnc2c1ncn2[C@@H]1O[C@H](COS(=O)(=O)[O-])[C@@H](O)[C@H]1O nan
660350 55444 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
CHEMBL1413816 55444 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
CHEMBL1619747 55444 6 None -70 2 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 265 2 0 3 2.6 O=C(OC1CN2CCC1CC2)c1cccc(Cl)c1 nan
24892704 71796 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 0 8 2.4 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1967784 71796 8 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 462 8 0 8 2.4 COCCn1/c(=N\C(=O)CCS(=O)(=O)c2ccccc2)sc2cc(C(=O)OC)ccc21 nan
2815701 105449 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 4 2.6 Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(N(C)C)cc2)cc1 nan
CHEMBL312032 105449 9 None - 1 Human 5.2 pPotency = 5.2 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 333 4 2 4 2.6 Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(N(C)C)cc2)cc1 nan
664514 46472 11 None 3 2 Human 6.1 pPotency = 6.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 0 7 3.0 CCOC(=O)CC(=O)CSc1ncnc2c1oc1ccccc12 nan
CHEMBL1537230 46472 11 None 3 2 Human 6.1 pPotency = 6.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 330 6 0 7 3.0 CCOC(=O)CC(=O)CSc1ncnc2c1oc1ccccc12 nan
4679126 22665 14 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 9 4.3 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
CHEMBL1327057 22665 14 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 482 7 1 9 4.3 CCOc1ccc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2c2nc(C)c(C(=O)OC)s2)cc1 nan
16030531 24116 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 4 4.9 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
CHEMBL1338691 24116 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 399 8 1 4 4.9 CCCCNC(=O)CSc1nc2ccccc2nc1Cc1ccc(Cl)cc1 nan
1371049 24395 11 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 3.6 COc1ccc(Cl)cc1C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 nan
CHEMBL1341278 24395 11 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 396 4 1 6 3.6 COc1ccc(Cl)cc1C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 nan
3236027 25112 10 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 7 3.9 COc1ccc(N2CCN(c3ccc(NC(=O)c4ccc5c(c4)OCO5)cc3C#N)CC2)cc1 nan
CHEMBL1347313 25112 10 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 7 3.9 COc1ccc(N2CCN(c3ccc(NC(=O)c4ccc5c(c4)OCO5)cc3C#N)CC2)cc1 nan
1208330 25323 16 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 0 5 4.6 CCN(CC)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
CHEMBL1349151 25323 16 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 6 0 5 4.6 CCN(CC)CCn1c2ccccc2c2nc3ccc([N+](=O)[O-])cc3cc21 nan
3414203 26207 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 5 2.9 Cn1/c(=N\C(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)sc2cc(F)ccc21 nan
CHEMBL1357194 26207 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 3 0 5 2.9 Cn1/c(=N\C(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)sc2cc(F)ccc21 nan
1920995 26870 8 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 3 4.1 Cc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
CHEMBL1363550 26870 8 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 4 2 3 4.1 Cc1ccc(OCC(=O)NC(=S)Nc2ccc3c4c(cccc24)CC3)cc1 nan
15988900 28222 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 7 5.1 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Br)cc3)on2)sc(C(C)=O)c1C nan
CHEMBL1373810 28222 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 476 6 1 7 5.1 CCOC(=O)c1c(NC(=O)c2cc(-c3ccc(Br)cc3)on2)sc(C(C)=O)c1C nan
1450216 30088 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 4.2 Cc1ccc(C)c2nc(SCC(=O)NCc3cccs3)c(C#N)cc12 nan
CHEMBL1389491 30088 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 367 5 1 5 4.2 Cc1ccc(C)c2nc(SCC(=O)NCc3cccs3)c(C#N)cc12 nan
3330912 30759 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 5 5.9 CCOc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
CHEMBL1395727 30759 13 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 475 7 1 5 5.9 CCOc1ccc(NC(=O)CSc2nc(-c3ccc(F)cc3)cc(C(F)(F)F)c2C#N)cc1 nan
16033852 31110 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 6 4.1 O=c1c2ccccc2nc2sc(Nc3cccc(C(F)(F)F)c3)nn12 nan
CHEMBL1399988 31110 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 362 2 1 6 4.1 O=c1c2ccccc2nc2sc(Nc3cccc(C(F)(F)F)c3)nn12 nan
20923127 31132 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCC(C)C1 nan
CHEMBL1400119 31132 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 429 5 0 6 2.3 COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)N1CCCC(C)C1 nan
692203 31613 16 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 5 4.5 O=C(Oc1ccccc1)Oc1ccc2c(c1)oc(=O)c1ccccc12 nan
CHEMBL1404472 31613 16 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 332 2 0 5 4.5 O=C(Oc1ccccc1)Oc1ccc2c(c1)oc(=O)c1ccccc12 nan
16745677 32044 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 9 0 9 6.0 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1Cc1ccc2c(c1)OCO2 nan
CHEMBL1408237 32044 0 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 581 9 0 9 6.0 CCCCC1=CC2=C(c3ccco3)C(=O)C(C)(OC(=O)c3ccc(OC)cc3)C(=O)C2=CN1Cc1ccc2c(c1)OCO2 nan
16010801 35108 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 3.1 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1OC nan
CHEMBL1433929 35108 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 488 8 1 8 3.1 COc1ccc(CCn2c(=O)c3cccnc3n(CC(=O)Nc3c(C)cccc3C)c2=O)cc1OC nan
4107570 39795 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 4 4.8 COc1ccc2c(c1)-c1nc(NC(=O)c3ccc(Cl)cc3)sc1CC2 nan
CHEMBL1476611 39795 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 370 3 1 4 4.8 COc1ccc2c(c1)-c1nc(NC(=O)c3ccc(Cl)cc3)sc1CC2 nan
16009524 39821 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 7 4.3 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1C nan
CHEMBL1476936 39821 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 449 7 1 7 4.3 Cc1ccc(OCC(=O)Nc2ccc(OCc3cc(=O)n4c(C)csc4n3)cc2)cc1C nan
7184626 40630 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 3.0 CCOc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
CHEMBL1484029 40630 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 411 7 1 8 3.0 CCOc1ccc(NC(=O)CCCc2nnc3n(C)c(=O)c4sccc4n23)cc1 nan
4423184 44173 11 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 8 2.6 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(C(=O)OC)ccc21 nan
CHEMBL1516075 44173 11 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 428 5 0 8 2.6 COCCn1/c(=N/C(=O)c2ccc3c(c2)OCCO3)sc2cc(C(=O)OC)ccc21 nan
2946893 44517 12 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 1 7 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
CHEMBL1519514 44517 12 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 474 9 1 7 3.2 CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
2808378 10387 28 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 2.9 CC(=O)c1sccc1NC(=O)c1ccccc1C(=O)O nan
CHEMBL1162443 10387 28 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 289 4 2 4 2.9 CC(=O)c1sccc1NC(=O)c1ccccc1C(=O)O nan
2085722 22450 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 7 1.6 CCCNC(=O)COC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
CHEMBL1324965 22450 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 345 5 1 7 1.6 CCCNC(=O)COC(=O)c1cc2c(=O)n3ccccc3nc2s1 nan
2918454 24055 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 4.1 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(F)cc2)nc1C nan
CHEMBL1338266 24055 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 456 5 1 8 4.1 COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(F)cc2)nc1C nan
4902571 24242 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 8 4.3 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(C)cc2)s1 nan
CHEMBL1339921 24242 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 427 5 1 8 4.3 CSc1nnc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2ccc(C)cc2)s1 nan
15990443 26165 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 5.8 COc1cc(Cl)c(C)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
CHEMBL1356755 26165 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 463 4 1 5 5.8 COc1cc(Cl)c(C)cc1NC(=O)c1cn(C2CCCC2)c(=O)c2c1c1ccccc1n2C nan
3442498 27181 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 1 8 1.9 Cc1nnc(NC(=O)CSc2ccc([N+](=O)[O-])cn2)s1 nan
CHEMBL1366225 27181 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 311 5 1 8 1.9 Cc1nnc(NC(=O)CSc2ccc([N+](=O)[O-])cn2)s1 nan
18561048 28436 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
CHEMBL1375333 28436 10 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4cccnc4)n3n2)cc1 nan
5098091 29728 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 4 5.6 COc1ccc(-c2sc(C(=O)c3ccc(Cl)cc3Cl)cc2CC(=O)O)cc1 nan
CHEMBL1386663 29728 3 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 420 6 1 4 5.6 COc1ccc(-c2sc(C(=O)c3ccc(Cl)cc3Cl)cc2CC(=O)O)cc1 nan
1112430 36439 20 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 6 3.3 CCOC(=O)c1cccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
CHEMBL1447146 36439 20 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 381 6 1 6 3.3 CCOC(=O)c1cccc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)c1 nan
734580 37042 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 3 1 4 2.2 CC(=O)c1sc(NC(=O)C(C)C)nc1C nan
CHEMBL1451957 37042 15 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 226 3 1 4 2.2 CC(=O)c1sc(NC(=O)C(C)C)nc1C nan
18561036 37825 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
CHEMBL1458644 37825 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 419 6 2 8 2.9 CC(=O)Nc1ccc(NC(=O)CSc2ccc3nnc(-c4ccccn4)n3n2)cc1 nan
16195440 38510 1 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.7 CCn1c(=O)c2cc(C(=O)Nc3cccc(C(C)=O)c3)sc2c2ccccc21 nan
CHEMBL1464378 38510 1 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 390 4 1 5 4.7 CCn1c(=O)c2cc(C(=O)Nc3cccc(C(C)=O)c3)sc2c2ccccc21 nan
16008699 39610 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 9 2.5 CCOc1ccc(-c2nc(C(N)=O)c3c(n2)n(-c2ccc4c(c2)OCO4)c(=O)n3CC)cc1 nan
CHEMBL1474027 39610 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 447 6 1 9 2.5 CCOc1ccc(-c2nc(C(N)=O)c3c(n2)n(-c2ccc4c(c2)OCO4)c(=O)n3CC)cc1 nan
2746740 41802 5 None 2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 2 6 5.5 O=C(Nc1ccc(Cl)cc1)Nc1ccccc1Sc1ncc([N+](=O)[O-])s1 nan
CHEMBL1493199 41802 5 None 2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 406 5 2 6 5.5 O=C(Nc1ccc(Cl)cc1)Nc1ccccc1Sc1ncc([N+](=O)[O-])s1 nan
17469833 42912 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 6 3.0 COc1ccccc1NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
CHEMBL1503328 42912 9 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 355 3 1 6 3.0 COc1ccccc1NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 nan
17581208 43090 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1ccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)cc1 nan
CHEMBL1505004 43090 8 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 436 5 1 8 3.1 COc1ccc(NC(=O)Cn2c3ccc(OC)cc3c3nc4n(c(=O)c32)CCS4)cc1 nan
3207506 43347 4 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1ccc2nc(SCC(=O)NCc3cccs3)c(C#N)cc2c1 nan
CHEMBL1507076 43347 4 None 1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 353 5 1 5 3.9 Cc1ccc2nc(SCC(=O)NCc3cccs3)c(C#N)cc2c1 nan
16018870 44603 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 4 0 7 6.2 Cc1oc(-c2ccc(Cl)cc2)nc1CSc1nnc(C)n2c1cc1sccc12 nan
CHEMBL1520274 44603 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 426 4 0 7 6.2 Cc1oc(-c2ccc(Cl)cc2)nc1CSc1nnc(C)n2c1cc1sccc12 nan
1130973 46889 6 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.1 Cc1ccccc1OCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N nan
CHEMBL1540811 46889 6 None -2 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 433 6 2 5 5.1 Cc1ccccc1OCC(=O)Nc1sc(C(=O)Nc2cccc(C)c2C)c(C)c1C#N nan
724891 47315 31 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 5 3.5 O=C(O)CSc1ncnc2scc(-c3ccccc3)c12 nan
CHEMBL1544233 47315 31 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 302 4 1 5 3.5 O=C(O)CSc1ncnc2scc(-c3ccccc3)c12 nan
1004390 47836 12 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 5 4.1 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3ccccc3)n2)c1 nan
CHEMBL1548754 47836 12 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 403 8 1 5 4.1 COc1cccc(-c2ccc(C#N)c(SCC(=O)NCCc3ccccc3)n2)c1 nan
1450522 48778 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 3.2 COc1ccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc2c1 nan
CHEMBL1558667 48778 5 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 404 4 1 6 3.2 COc1ccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc2c1 nan
16021094 49120 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 4.3 CCc1cccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
CHEMBL1561841 49120 5 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 382 3 1 4 4.3 CCc1cccc(NC(=O)c2cn3c4c(ccc(Cl)c4c2=O)OC(C)C3)c1 nan
4585955 50561 7 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 6 1 9 4.4 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)CC1 nan
CHEMBL1574238 50561 7 None -1 2 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 560 6 1 9 4.4 O=C(O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Br)ccc4n3)nc3ccsc3c2=O)CC1 nan
16025788 52382 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 4 5.7 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4c(C)cc5ccccc54)s3)CC2)cc1 nan
CHEMBL1590035 52382 6 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 485 6 1 4 5.7 CCc1ccc(CNC(=O)C2CCN(C(=O)c3ccc(-n4c(C)cc5ccccc54)s3)CC2)cc1 nan
7184644 52486 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 2 8 0.2 CC(=O)NCCNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
CHEMBL1591356 52486 7 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 376 7 2 8 0.2 CC(=O)NCCNC(=O)CCCc1nnc2n(C)c(=O)c3sccc3n12 nan
16010575 52556 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 3.2 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c(C)c1 nan
CHEMBL1592228 52556 4 None - 1 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 408 6 1 6 3.2 Cc1cc(C)c(NC(=O)Cn2c(=O)n(CCC(C)C)c(=O)c3cccnc32)c(C)c1 nan
101430 96433 19 None -1949 5 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 4 9 0.2 OC[C@H]1O[C@@H](n2cnc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O nan
CHEMBL262083 96433 19 None -1949 5 Human 5.1 pPotency = 5.1 Functional
PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory) PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Relaxin Receptor RXFP1. (Class of assay: confirmatory)
ChEMBL 343 4 4 9 0.2 OC[C@H]1O[C@@H](n2cnc3c(Nc4ccccc4)ncnc32)[C@H](O)[C@@H]1O nan
13273 549 0 None 31 3 Human 7.8 pEC50 = 7.8 Functional
Determined in a cAMP assayDetermined in a cAMP assay
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 549 0 None 31 3 Human 7.8 pEC50 = 7.8 Functional
Determined in a cAMP assayDetermined in a cAMP assay
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
12501 3455 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Determined in a cell-based cAMP assay.Determined in a cell-based cAMP assay.
Guide to Pharmacology None None None None 33555858
12501 3455 0 None - 1 Human 9.7 pEC50 = 9.7 Functional
Determined in a cell-based cAMP assay.Determined in a cell-based cAMP assay.
Guide to Pharmacology None None None None 36443381
1989 3305 0 None 17 3 Human 10.4 pEC50 = 10.4 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 18434306
13273 549 0 None -309 3 Rat 5.3 pEC50 = 5.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 549 0 None -309 3 Rat 5.3 pEC50 = 5.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
13273 549 0 None -31 3 Mouse 6.3 pEC50 = 6.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
163395232 549 0 None -31 3 Mouse 6.3 pEC50 = 6.3 Functional
UnclassifiedUnclassified
Guide to Pharmacology 544 9 3 5 4.7 COC1=CC(F)=C(O[C@H]2CC[C@](C(O)=O)(C)CC2)C=C1C(N[C@H]3[C@@H](C(NCC4(CCC4)C)=O)[C@@H]5CC[C@H]3C5)=O 38502782
56593349 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
56593349 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
56593349 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
8322 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
8322 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
8322 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
CHEMBL3716980 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23764525
CHEMBL3716980 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 23905199
CHEMBL3716980 2571 30 None - 1 Human 7.0 pEC50 = 7.0 Functional
UnclassifiedUnclassified
Guide to Pharmacology 506 7 2 5 5.3 CC(Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(c1)S(=O)(=O)C(F)(F)F)C 28592882
11898 1119 0 None - 1 Human 7.9 pEC50 = 7.9 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 33555858
8346 202 0 None 165 2 Human 8.2 pEC50 = 8.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21878627
11462 3748 0 None - 1 Human 9.1 pEC50 = 9.1 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 30594862
134813895 203 0 None - 1 Human 9.8 pEC50 = 9.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
8349 203 0 None - 1 Human 9.8 pEC50 = 9.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
1988 3306 0 None - 1 Human 8.8 pEC50 None 8.8 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 16411781
4371 715 0 None - 1 Human 6.2 pIC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20043231
4371 715 0 None - 1 Human 6.2 pIC50 = 6.2 Functional
UnclassifiedUnclassified
Guide to Pharmacology None None None None 24812057


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162654489 180635 0 None - 1 Rat 9.3 pEC50 = 9.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180635 0 None - 1 Rat 9.3 pEC50 = 9.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162672610 183016 0 None - 0 Rat 9.1 pEC50 = 9.1 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4793799 183016 0 None - 0 Rat 9.1 pEC50 = 9.1 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 4064 171 53 59 -9.7 CCCCCCCCCCCCCCCCC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)CNC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162664297 182081 0 None - 0 Rat 8.3 pEC50 = 8.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4781560 182081 0 None - 0 Rat 8.3 pEC50 = 8.3 Binding
Agonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assayAgonist activity at rat RXFP1 expressed in human HEK296 cells assessed as increase in IBMX-induced cAMP accumulation pretreated with IBMX for 40 mins followed by compound addition and measured after 30 mins by HTRF assay
ChEMBL 2767 100 45 38 -12.7 CCCC[C@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](C)CNC(=O)[C@@H](C)CNC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(C)=O)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)NC[C@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
162654489 180635 0 None - 1 Human 9.0 pKi = 9.0 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
CHEMBL4754949 180635 0 None - 1 Human 9.0 pKi = 9.0 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 5876 136 86 84 -20.9 CC[C@H](C)[C@@H]1NC(=O)[C@H](C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(=O)O)C(C)C)[C@@H](C)CC)CSSC[C@@H]2NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H](N)CC(C)C)CSCCSC[C@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc3cnc[nH]3)NC2=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccccc2)C(=O)NC(C(=O)O)CSSC[C@@H](C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O)NC1=O 10.1021/acs.jmedchem.0c01533
162662592 181969 0 None - 1 Human 5.5 pKi = 5.5 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
CHEMBL4780098 181969 0 None - 1 Human 5.5 pKi = 5.5 Binding
Displacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assayDisplacement of Eu3+-labelled H2 relaxin from human RXFP1 expressed in human HEK-293T cells in presence of 10 % FCS by competition binding assay
ChEMBL 2985 104 48 42 -13.7 CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(N)=O)[C@@H](C)O 10.1021/acs.jmedchem.0c01533
12502 2419 0 None 24 2 Human 10.1 pKd = 10.1 Binding
Binding affinity determined by SPR.Binding affinity determined by SPR.
Guide to Pharmacology None None None None 36780899
12502 2419 0 None -24 2 Mouse 8.7 pKd = 8.7 Binding
Binding affinity determined by SPR.Binding affinity determined by SPR.
Guide to Pharmacology None None None None 36780899
8346 202 0 None 9 2 Human 7.0 pKd = 7.0 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 21878627
3874 1603 0 None - 1 Human 9.0 pKd = 9 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 19343240
3874 1603 0 None - 1 Human 9.3 pKd = 9.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 22425984
1993 3304 0 None - 1 Human 7.3 pKd None 7.3 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1992 3303 0 None 15 2 Human 9.1 pKd None 9.1 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1994 3302 0 None 39 2 Human 9.4 pKd None 9.4 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
9321 564 0 None - 1 Human 5.5 pKi = 5.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 30155023
9321 564 0 None - 1 Human 5.5 pKi = 5.5 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 32295457
4371 715 0 None - 1 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 20043231
4371 715 0 None - 1 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 24812057
1995 2044 0 None -16982 2 Human 5.7 pKi = 5.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23303914
134813895 203 0 None - 1 Human 9.2 pKi = 9.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
8349 203 0 None - 1 Human 9.2 pKi = 9.2 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 23024363
1989 3305 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 12506116
1989 3305 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866
1989 3305 0 None -1 3 Human 9.7 pKi = 9.7 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 18434306
1990 3307 0 None -14 4 Human 7.8 pKi None 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 12506116
1990 3307 0 None -14 4 Human 7.8 pKi None 7.8 Binding
UnclassifiedUnclassified
Guide to Pharmacology None None None None 15649866